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1 Infections After Valve Replacements are Rare but Life ...
http://www.cardiosmart.org/news/2019/11/infections-after-valve-replacements-are-rare-but-life-threatening
The infection is a known complication of valve replacement and can occur within days, months or years after the procedure. It is a potentially ...
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2 Heart Valve Infections | Valvular Heart Disease - JAMA Network
https://jamanetwork.com/journals/jama/fullarticle/206282
Prosthetic (replaced) or repaired heart valves are prone to infection. Growths of infectious tissue on heart valves are called vegetations ...
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3 Surgery for Infective Endocarditis - Cleveland Clinic
https://my.clevelandclinic.org/health/treatments/17125-infective-endocarditis-surgery
Normal heart valves are very resistant to infection. However, bacteria can attach to defects on the surface of diseased valves. Replacement ...
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4 Infective Endocarditis After Surgical and Transcatheter Aortic ...
https://www.ahajournals.org/doi/10.1161/JAHA.120.017347
Surgical prosthetic valve endocarditis (PVE) is a well‐studied morbid condition that accounts for 10% to 30% of all cases of infective ...
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5 Heart Valves and Infective Endocarditis
https://www.heart.org/en/health-topics/heart-valve-problems-and-disease/heart-valve-problems-and-causes/heart-valves-and-infective-endocarditis
Infective endocarditis, also called bacterial endocarditis, is an infection caused by bacteria that enter the bloodstream and settle in the ...
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6 Endocarditis - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/endocarditis/symptoms-causes/syc-20352576
Endocarditis is usually caused by an infection. Bacteria, fungi or other germs get into the bloodstream and attach to damaged areas in the heart ...
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7 Endocarditis - NHS
https://www.nhs.uk/conditions/endocarditis/
Endocarditis is treated with a course of antibiotics given via a drip. You'll need to be admitted to hospital for this. Some people also need surgery to repair ...
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8 Bacterial Endocarditis | Cedars-Sinai
https://www.cedars-sinai.org/health-library/diseases-and-conditions/b/bacterial-endocarditis-adult.html
Bacterial endocarditis is a bacterial infection of the inner layer of the heart or the heart valves. The heart has 4 valves. These valves help the blood ...
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9 Antibiotics to prevent heart valve infections (Beyond the Basics)
https://www.uptodate.com/contents/antibiotics-to-prevent-heart-valve-infections-beyond-the-basics/print
... (PVE) refers to infection of one or more prosthetic heart valves. The timing of the infection after surgical valve replacement ref.
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10 Infective Endocarditis - Heart and Blood Vessel Disorders
https://www.merckmanuals.com/home/heart-and-blood-vessel-disorders/endocarditis/infective-endocarditis
Septic shock is life-threatening low blood pressure ... read more , a severe blood infection, introduces a large number of bacteria into the bloodstream. When ...
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11 Infection risk and heart valve surgery - Heart Matters magazine
https://www.bhf.org.uk/informationsupport/heart-matters-magazine/medical/ask-the-experts/infection-risk
Not too worried. The risk of developing the infection is extremely low - estimated at 1 in 5000 patients who had heart valve surgery and even lower for other ...
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12 Endocarditis - Symptoms and Causes - Penn Medicine
https://www.pennmedicine.org/for-patients-and-visitors/patient-information/conditions-treated-a-to-z/endocarditis
Endocarditis is inflammation of the inside lining of the heart chambers and heart valves (endocardium). It is caused by a bacterial or, rarely a fungal ...
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13 Transcatheter aortic valve replacement associated infective ...
https://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-021-02364-0
Transcatheter valve replacement (TAVR) is an important therapeutic intervention for patients with aortic valve stenosis. As TAVR has become ...
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14 Infective Endocarditis - Medscape Reference
https://emedicine.medscape.com/article/216650-overview
Infective endocarditis (IE) is an infection of the endocardial surfaces of the heart—usually of 1 or more cardiac valves; to a lesser degree ...
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15 Current AATS guidelines on surgical treatment of infective ...
https://www.annalscts.com/article/view/16669/html
Standard indications for surgery are severe heart failure, severe valve dysfunction, prosthetic valve infection, invasion beyond the valve ...
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16 Infective Endocarditis - NORD (National Organization for Rare ...
https://rarediseases.org/rare-diseases/endocarditis-infective/
For those with heart valve replacements, the risk of infection is highest within the first year after the procedure takes place.
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17 What is Endocarditis? - WebMD
https://www.webmd.com/heart-disease/what-is-endocarditis
In some cases, endocarditis requires surgery to completely clear it, or to replace a damaged heart valve. Whether or not you need surgery will ...
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18 Aortic valve infection
https://www.jtcvs.org/article/S0022-5223(19)34813-5/pdf
class, prosthetic valve endocarditis, infection status (lowerin patients with healed ... Ten years after aortic valve replacement, 79 % of valves were.
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19 Bacteremia among Aortic-Valve Surgery Patients -- Boston
https://www.cdc.gov/mmwr/preview/mmwrhtml/00000209.htm
Clinical onset of infection ranged from 4 days to 2 weeks after surgery; 2 patients had mediastinitis in addition to bacteremia. The infected patients ranged in ...
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20 Bicuspid Aortic Valve—A Silent Danger: Analysis of 50 Cases ...
https://academic.oup.com/cid/article/30/2/336/380582
The 4 patients who died after valve surgery had S. aureus endocarditis, 1 with a methicillin-resistant S. aureus (MRSA). Two of the 4 patients died after a ...
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21 Transcatheter Aortic Valve Replacement for Residual Lesion ...
https://www.sciencedirect.com/science/article/pii/S1936879820312322
Among 2,920 patients treated with TAVR, 54 (1.8%) presented with prior AV-IE with residual valvular lesion and healed infection. They had a ...
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22 Current Challenges in the Management of Infective Endocarditis
https://www.frontiersin.org/articles/10.3389/fmed.2021.641243/full
The infection affects the endocardial surface of the heart, most commonly the valves, but also may occur on mural endocardium, on cardiac septal ...
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23 Risk of infective endocarditis after surgical and transcatheter ...
https://heart.bmj.com/content/108/8/639
Prosthetic valve infective endocarditis (IE) is a potentially life-threatening complication of aortic valve replacement. The relative incidence of IE after SAVR ...
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24 Bacterial Endocarditis: What Should Heart Valve Patients Know?
https://www.heart-valve-surgery.com/learning/bacterial-endocarditis/
Heart valves are also susceptible to life-threatening infections. Bacterial Endocarditis, for example, is a common infection within the mitral ...
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25 Heart Valve Repair or Replacement Surgery
https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/heart-valve-repair-or-replacement-surgery
Valves can become narrow and stiff from infection (such as rheumatic fever or staph) and aging. If one or more valves become leaky, blood leaks backwards, which ...
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26 Infective endocarditis post-transcatheter aortic valve ... - PLOS
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0225077
The clinical picture of post-TAVI IE varies from nonspecific symptoms to acute infection or sepsis with fever, heart failure or embolic stroke.
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27 Risk Factors and Outcomes Associated With Sepsis After ...
https://journals.sagepub.com/doi/abs/10.1177/1089253218785362
Purpose. Sepsis causes significant morbidity and mortality after cardiac surgery and carries a significant burden on health care costs.
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28 Infective endocarditis - Heart and Stroke Foundation of Canada
https://www.heartandstroke.ca/heart-disease/conditions/infective-endocarditis
Infective endocarditis is an inflammation of the heart caused by a bacterial or fungal infection of the heart valves or the inner lining of the heart ( ...
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29 Endocarditis in Patients with Aortic Valve Prosthesis - MDPI
https://www.mdpi.com/2079-6382/10/1/50/htm
Prosthetic valve infective endocarditis (PVE) is the most worrisome complication after valve replacement, as it still carries high mortality and morbidity rate.
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30 Aortic and mitral valve surgery for infective endocarditis with ...
https://jtd.amegroups.com/article/view/37556/html
As expected, the Commando procedure was significantly associated with early morbidity and mortality. The major complications were reported as bleeding, sepsis, ...
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31 Endocarditis: Risk Factors, Symptoms, and Diagnosis
https://www.healthline.com/health/endocarditis
Infective endocarditis is an infection in the heart valves or endocardium. The endocardium is the lining of the interior surfaces of the chambers of the heart.
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32 Infective Endocarditis After TAVR Often Deadly
https://www.medpagetoday.com/cardiology/pci/58493
Two-thirds died in the hospital after infection. ... does not bode well for patients after transcatheter aortic valve replacement (TAVR), ...
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33 Aortic root abscess – a deadly complication of UTI-induced ...
https://pulmonarychronicles.com/index.php/pulmonarychronicles/article/view/933/2029
Bacteremia and sepsis are relatively common in the hospital ward and can arise from a wide variety of infectious sites. A history of valve replacement places ...
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34 Endocarditis - UCSF Department of Surgery
https://surgery.ucsf.edu/conditions--procedures/endocarditis.aspx
In some cases, surgery is needed to repair or replace a damaged heart valve or to help clear up the infection. IE due to an infection with fungi often requires ...
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35 Surgery for Active Infective Endocarditis of the Aortic Valve ...
https://www.heartlungcirc.org/article/S1443-9506(18)31771-2/fulltext
Thirty-three (33) patients (19.6%) had major adverse events postoperatively. This included new stroke, cardiogenic shock and/or septic shock.
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36 Feature | Infective Endocarditis: Words of Caution For ...
https://www.acc.org/latest-in-cardiology/articles/2022/03/12/01/42/feature-infective-endocarditis-words-of-caution-for-management
Figures 1 and 2 Bicuspid Aortic Valve Endocarditis ... whether the infection is within one year of surgery (early or late PVE).
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37 Heart conditions - endocarditis - Better Health Channel
https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/heart-conditions-endocarditis
The infection causes inflammation and blood clots, while the body's natural healing process causes scarring. A scarred endocardium or heart valve is susceptible ...
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38 Lactococcus garvieae: An Uncommon Human Pathogen ...
https://www.hindawi.com/journals/cric/2021/5569533/
garvieae affecting a valve-in-valve transcatheter aortic valve replacement that was successfully treated. Specific guidelines for the management of these ...
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39 Streptococcus sanguinis Endocarditis of Bicuspid Aortic Valve ...
https://www.cureus.com/articles/62769-streptococcus-sanguinis-endocarditis-of-bicuspid-aortic-valve-presenting-as-septic-arthritis-of-lumbar-facet-joint
The aim of surgery is to both eradicate the infection and correct hemodynamic abnormalities. Valve replacement is usually essential but is ...
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40 Surgical treatment and long-term outcome of aortic valve ...
https://link.springer.com/article/10.1007/s12471-020-01409-x
Aortic valve endocarditis is occasionally complicated by periannular spreading of the infection and abscess formation, leading to a more ...
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41 Endocarditis: Symptoms, causes, and treatment
https://www.medicalnewstoday.com/articles/151016
Surgery may repair a heart defect or damaged heart valves, replace them with artificial ones, or drain the abscesses that have developed within the heart muscle ...
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42 Acute infective endocarditis masquerading as septic shock ...
https://onlinelibrary.wiley.com/doi/10.1002/ccr3.3261
The patient was placed on cefazolin treatment and underwent emergent MV replacement. Gross inspection of the valve during surgery confirmed ...
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43 Management of Bacterial Endocarditis - AAFP
https://www.aafp.org/pubs/afp/issues/2000/0315/p1725.html
Native valve infection by methicillin-susceptible staphylococci is ... cause of endocarditis involving native heart valves in patients with ...
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44 Transcatheter Aortic Valve Replacement–Associated Infective ...
https://www.structuralheartjournal.org/article/S2474-8706(22)01055-7/fulltext
Two patients underwent surgery, of whom one died on day 30 postoperatively from sepsis. Mortality due to IE occurred in 25% of cases in the ...
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45 Nocardial endocarditis after aortic valve replacement
https://www.tandfonline.com/doi/pdf/10.3109/14017438809106078
Nocardial sepsis occurred after aortic valve replacement in two patients. A septic suture aneurysm of the aortotomy was resected and the prosthesis ...
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46 Infective Endocarditis • LITFL • CCC Cardiology
https://litfl.com/infective-endocarditis/
... typically affecting the heart valves and usually caused by infection and can ... aortic and mitral valve; haemodialysis; high risk surgery (e.g. dental, ...
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47 Septic Embolism: A Potentially Devastating Complication of ...
https://www.intechopen.com/chapters/52116
Major risk factors for IE include underlying heart disease, cardiac surgery and interventional procedures, prosthetic valve, ...
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48 How soon should patients with infective endocarditis be ...
https://www.ccjm.org/content/85/5/362
INDICATIONS FOR EARLY SURGERY · Left ventricular dysfunction and heart failure · Uncontrolled persistent infection · Right-sided infective ...
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49 Endocarditis - MyHealth Alberta
https://myhealth.alberta.ca/Health/Pages/conditions.aspx?hwid=hw164664
Endocarditis is an infection of the heart's valves and inner lining of the ... need surgery to repair or replace a heart valve or to prevent complications.
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50 FDG-PET/CT for the detection of infection following aortic root ...
https://jnm.snmjournals.org/content/61/supplement_1/1614
Background: Infection following an aortic root replacement procedure is associated with significant morbidity and mortality but diagnosis can be ...
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51 Infective endocarditis - Wikipedia
https://en.wikipedia.org/wiki/Infective_endocarditis
Infective endocarditis is an infection of the inner surface of the heart, usually the valves. Signs and symptoms may include fever, small areas of bleeding ...
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52 Elderly versus non-elderly patients undergoing surgery for left ...
https://www.nature.com/articles/s41598-020-59657-1
Infective endocarditis (IE) is a serious infection associated with significant ... If the vegetations were located in the aortic valve, ...
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53 Infective Endocarditis | IE - MedlinePlus
https://medlineplus.gov/endocarditis.html
Once they get inside your heart, the germs can attach to the lining or get trapped in the valves. They start to grow, causing an infection. If ...
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54 Aortic Valve Endocarditis Article - StatPearls
https://www.statpearls.com/ArticleLibrary/viewarticle/17751
The term native valve endocarditis denotes a cardiac infection that ... surgery or percutaneous transcatheter aortic valve replacement.[3] ...
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55 Endocarditis in Dogs - VCA Animal Hospitals
https://vcahospitals.com/know-your-pet/endocarditis-in-dogs
Endocarditis refers to an infection of a heart valve. While endocarditis can affect any of the heart valves, the most commonly affected valves are the ...
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56 Endocarditis - EMCrit Project
https://emcrit.org/ibcc/endo/
Valve regurgitation or fistula causing heart failure. ... prior to valve replacement surgery, to avoid infection of the fresh valve.
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57 Cardiac surgery in infective endocarditis and predictors of in ...
https://www.revportcardiol.org/en-cardiac-surgery-in-infective-endocarditis-articulo-S2174204920301537
The median age was 72 years. IE was acquired mainly in the community (69%), and involved the native aortic valve in 54% of patients, biological prosthetic ...
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58 Endocarditis - Columbia University Department of Surgery
https://columbiasurgery.org/conditions-and-treatments/endocarditis
The best outcome in endocarditis requires specialists in heart medicine, heart surgery and infectious disease. Once the cause of the infection has been ...
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59 Anesthesia Considerations in Infective Endocarditis
https://pubs.asahq.org/anesthesiology/article/136/4/633/118378/Anesthesia-Considerations-in-Infective
Indications for surgery comprise heart failure, uncontrolled infection, ... after transcatheter aortic valve replacement complicated by stroke.54.
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60 Infective endocarditis - Knowledge @ AMBOSS
https://www.amboss.com/us/knowledge/Infective_endocarditis/
Surgery · Prosthetic valve endocarditis · Valve dysfunction leading to heart failure · Uncontrolled infection: e.g., enlarging vegetation, ...
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61 Damage to the Aortic Valve as a Cause of Death in Bacterial ...
https://www.acpjournals.org/doi/10.7326/0003-4819-55-4-562
by L COHEN · 1961 · Cited by 62 —
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62 Recurrent pyarthrosis of the knee causing aortic valve ...
https://cardiovascmed.ch/article/doi/cvm.2016.00447
The initial finding was a perforation of the left aortic valve cusp ... septic arthritis, relapse endocarditis, aortic root replacement ...
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63 Five-Year Outcomes of Transcatheter or Surgical Aortic-Valve ...
https://www.nejm.org/doi/full/10.1056/NEJMoa1910555
At 5 years, more patients in the TAVR group than in the surgery group had at least mild paravalvular aortic regurgitation (33.3% vs. 6.3%).
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64 Bentall Surgery for Infective Endocarditis: A Biointegral ...
https://www.ctsnet.org/article/bentall-surgery-infective-endocarditis-biointegral-bioconduit-subannular-implantation
Bentall surgery, often required in patients with an aortic valve prosthesis infection, represents a great surgical challenge.
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65 Bacterial Endocarditis in Children - Health Encyclopedia
https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid=P01768
Surgery. Some children may need heart valve surgery if there is severe heart valve damage due to the infection. This is done to fix or replace a damaged heart ...
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66 Latent Infective Endocarditis: Epidemiology and Clinical ...
https://www.annalsthoracicsurgery.org/article/S0003-4975(04)01194-4/abstract
Age range was 17 to 87 years (mean, 63 ± 14 years). A total of 970 valves were replaced; in 374 patients (43.1%) the aortic valve, in 371 (42.7%) the mitral ...
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67 Prevalence and predictors of aortic root abscess among ...
https://tehj.springeropen.com/articles/10.1186/s43044-020-00098-6
Periannular extension of the infection can occur, causing periannular abscesses. Aortic root abscess has been found in up to 46% of aortic valve ...
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68 Surgical treatment of aortic valve endocarditis: a 26-year ...
http://bjcvs.org/article/2213/en-US/surgical-treatment-of-aortic-valve-endocarditis--a-26-year-experience
RESULTS: Two hundred and eighty-two procedures were performed. The most frequently performed procedure was aortic valve replacement with mechanical prosthesis ( ...
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69 Endocarditis Guide: Causes, Symptoms and Treatment Options
https://www.drugs.com/health-guide/endocarditis.html
In the 10% to 20% of endocarditis patients who have artificial heart valves, infections that follow within 60 days of valve surgery often are ...
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70 Cardiogenic and septic shock associated with aortic and mitral ...
https://www.researchgate.net/publication/326386372_Cardiogenic_and_septic_shock_associated_with_aortic_and_mitral_valve_infective_endocarditis_caused_by_Abiotrophia_Defectiva_from_a_urinary_tract_infection
Surgical replacement of both the mitral and aortic valves. was required. ... Cardiovascular, Abiotrophia defectiva, infective endocarditis, septic shock.
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71 Bioprosthetic Transcatheter Aortic Valve Replacement ...
https://www.consultant360.com/article/consultant360/bioprosthetic-transcatheter-aortic-valve-replacement-leading-infective
The most common complications of IE include congestive heart failure (CHF), pericarditis, septic embolization and perivalvular abscess.
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72 Endocarditis - Cardiovascular - Medbullets Step 2/3
https://step2.medbullets.com/cardiovascular/120026/endocarditis
An acute cardiac condition charaterized by Inflammation of the heart valve, typically secondary to bacterial infection.
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73 “Cardiovascular Shower” Infective Endocarditis Causing ...
https://www.journalmc.org/index.php/JMC/article/view/3102/2435
Infective endocarditis (IE) is the infection of the endocardium or valves of the heart. Morbidity and mortality rates are high if not recognized early and ...
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74 Transcatheter aortic valve replacement (TAVR)
https://www.edwards.com/therapies/transcatheter-aortic-valve-replacement-tavr
PARTNER 3: transcatheter or surgical aortic valve replacement in low risk patients ... in patients at risk for prosthetic valve infection and endocarditis.
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75 Injecting Drugs Can Ruin a Heart. How Many Second ...
https://www.nytimes.com/2018/04/29/health/drugs-opioids-addiction-heart-endocarditis.html
A life-threatening heart infection afflicts a growing number of people who ... A little over a year ago, he replaced a heart valve in a ...
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76 Infective Endocarditis: A Serious Infection Of The Heart
https://www.excel-medical.com/infective-endocarditis-a-serious-infection-of-the-heart/
An infection of the heart valve is a serious condition known as endocarditis. The condition is life-threatening if not treated promptly. A ...
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77 Endocarditis - ID Care
https://idcare.com/documents/Endocarditis.pdf
require valve replacement surgery - this becomes necessary in ... Before infection settles on a heart valve, it usually arrives there by way of the ...
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78 Treatment for Endocarditis | Everyday Health
https://www.everydayhealth.com/endocarditis/guide/treatment/
Surgery may be required to repair the damage. Your doctors may also recommend surgery to clear up the infection or to replace heart valves that ...
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79 Infective and Bacterial Endocarditis Symptoms, & Treatment
https://www.medicinenet.com/endocarditis/article.htm
In severe cases that damage the heart valves, surgical replacement of the ... The infection may be introduced during brief periods of having bacteria in the ...
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80 Infective Endocarditis Symptoms and Treatment - UPMC
https://www.upmc.com/services/heart-vascular/conditions-treatments/infective-endocarditis
Endocarditis is a bacterial infection in the bloodstream. ... In some cases, you may need surgery to replace the infected heart valve if: The infection ...
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81 Surgery of the Left Heart Valve Infective Endocarditis
https://thoracickey.com/surgery-of-the-left-heart-valve-infective-endocarditis/
Infective endocarditis (IE) is the most severe and devastating complication of heart valve disease, whether it is native valve endocarditis ...
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82 Infective Endocarditis, Animation - YouTube
https://www.youtube.com/watch?v=SCwm5k8ULGk
Alila Medical Media
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83 Prosthetic Valve Endocarditis - Infectious Disease Advisor
https://www.infectiousdiseaseadvisor.com/home/decision-support-in-medicine/infectious-diseases/prosthetic-valve-endocarditis/
Patients with extra cardiac infection complicating convalescence after valve surgery and patients with skin or mucosal conditions associated ...
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84 Predictors of Mortality in Redo Aortic Valve Replacement for ...
https://ejhm.journals.ekb.eg/article_268095_91128f0992dd81e3539b954190a84515.pdf
infection of a surgically implanted prosthetic valve or repaired native valve with ... replacement for prosthetic aortic valve endocarditis.
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85 Bacterial Endocarditis | Boston Children's Hospital
https://www.childrenshospital.org/conditions/bacterial-endocarditis
Bacterial endocarditis is an infection of the lining of the heart. ... a leaky or narrow valve, abnormal connections inside the heart, or previous surgery.
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86 Patch repair in infective native mitral valve endocarditis
https://mmcts.org/tutorial/1692
Surgical valve repair is an attractive alternative: It provides good valve repair durability ... The aortic valve seemed free of infection.
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87 Rare bacterial endocarditis and sepsis almost kills teen girl
https://www.today.com/health/rare-bacterial-endocarditis-sepsis-almost-kills-teen-girl-t121446
After open-heart surgery to replace an infected valve, ... Bacterial endocarditis is an infection in a heart valve or blood vessel that ...
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88 Infective Endocarditis Associated with Transcatheter Aortic ...
https://e-jcvi.org/DOIx.php?id=10.4250/jcu.2014.22.3.134
Recently, transcatheter aortic valve replacement (TAVR) has emerged as an alternative for the treatment of severe symptomatic aortic stenosis ...
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89 Transcatheter aortic valve replacement and Candida ... - OAText
https://www.oatext.com/Transcatheter-aortic-valve-replacement-and-Candida-parapsilosis-endocarditis-a-deadly-combination.php
Candida parapsilosis is the second most common fungus and many internal and external factors are related to the infection as contaminated ...
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90 Aortic Valve Repair and Replacement
https://nwregionalheart.com/diagnostics-and-treatments/heart-surgery/aortic-valve-repair-and-replacement/
Surgical options for aortic valves ... The aortic valve doesn't heal itself. When you have aortic valve disease — most often from stenosis (hardening or narrowing) ...
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91 Acute bacterial endocarditis - VisualDx
https://www.visualdx.com/visualdx/diagnosis/acute+bacterial+endocarditis?diagnosisId=52908&moduleId=101
Infection, including Candida infection, can occur after open heart surgery or valve replacement via catheter (TAVR). Patients typically have ...
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92 Aortic Valve Disease | The Patient Guide to Heart, Lung, and ...
https://ctsurgerypatients.org/adult-heart-disease/aortic-valve-disease
Aortic valve disease occurs when the aortic valve doesn't work properly; it either fails to close tightly (aortic regurgitation or insufficiency) or gets too ...
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93 Prosthetic Heart Valves - Zero To Finals
https://zerotofinals.com/medicine/cardiology/prostheticvalves/
Thrombus formation (blood stagnates and clots) · Infective endocarditis (infection in prosthesis) · Haemolysis causing anaemia (blood gets churned up in the valve).
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