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Google Keyword Rankings for : organic acidemia renal failure
1
Renal Involvement in Methylmalonic Aciduria - PMC - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733828/
In summary, the majority of patients with MMA develop renal impairment at a young age. Most patients are able to acidify the urine, have no overt proteinuria, ...
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733828/
In summary, the majority of patients with MMA develop renal impairment at a young age. Most patients are able to acidify the urine, have no overt proteinuria, ...
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2
Long-term renal outcome in methylmalonic acidemia in ...
https://ojrd.biomedcentral.com/articles/10.1186/s13023-021-01851-z
Chronic kidney disease (CKD) is one of the main long-term prognosis factors in methylmalonic acidemia (MMA), a rare disease of propionate ...
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https://ojrd.biomedcentral.com/articles/10.1186/s13023-021-01851-z
Chronic kidney disease (CKD) is one of the main long-term prognosis factors in methylmalonic acidemia (MMA), a rare disease of propionate ...
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3
Chronic kidney disease in propionic acidemia - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S1098360021012272
Propionic acidemia (PA) is a severe metabolic disorder characterized by multiorgan pathology, including renal disease. The prevalence of chronic kidney ...
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https://www.sciencedirect.com/science/article/pii/S1098360021012272
Propionic acidemia (PA) is a severe metabolic disorder characterized by multiorgan pathology, including renal disease. The prevalence of chronic kidney ...
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4
Mechanisms of Metabolic Acidosis–Induced Kidney Injury in ...
https://jasn.asnjournals.org/content/31/3/469
Chronic metabolic acidosis, defined as a serum bicarbonate level <22 mEq/L in a patient with normal pulmonary function, is common in CKD and reflects reduced ...
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https://jasn.asnjournals.org/content/31/3/469
Chronic metabolic acidosis, defined as a serum bicarbonate level <22 mEq/L in a patient with normal pulmonary function, is common in CKD and reflects reduced ...
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5
Chronic Metabolic Acidosis in Chronic Kidney Disease - FullText
https://www.karger.com/Article/FullText/510829
Background: Metabolic acidosis may be diagnosed as chronic (cMA) if it persists for at least 5 days, although an exact definition has not been ...
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https://www.karger.com/Article/FullText/510829
Background: Metabolic acidosis may be diagnosed as chronic (cMA) if it persists for at least 5 days, although an exact definition has not been ...
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6
Methylmalonic Acidemia with Renal Involvement
https://www.sjkdt.org/article.asp?issn=1319-2442;year=2001;volume=12;issue=1;spage=49;epage=53;aulast=Srinivas
A benign variant of MMA is a more frequent form of the disease. It occurs in older children who usually have low levels of methylmalanoic acid in blood and ...
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https://www.sjkdt.org/article.asp?issn=1319-2442;year=2001;volume=12;issue=1;spage=49;epage=53;aulast=Srinivas
A benign variant of MMA is a more frequent form of the disease. It occurs in older children who usually have low levels of methylmalanoic acid in blood and ...
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7
Renal growth in isolated methylmalonic acidemia - Nature
https://www.nature.com/articles/gim201342
In conclusion, mitochondrial dysfunction was found in all investigated tissues of six patients with organic acidemia presenting with severe complications.
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https://www.nature.com/articles/gim201342
In conclusion, mitochondrial dysfunction was found in all investigated tissues of six patients with organic acidemia presenting with severe complications.
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8
Isovaleric Acidemia - NORD (National Organization for Rare ...
https://rarediseases.org/rare-diseases/acidemia-isovaleric/
Organic acidemias are a group of disorders in which there is a genetic mutation in genes for enzyme(s) responsible for breaking down amino acids. There is an ...
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https://rarediseases.org/rare-diseases/acidemia-isovaleric/
Organic acidemias are a group of disorders in which there is a genetic mutation in genes for enzyme(s) responsible for breaking down amino acids. There is an ...
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9
Progressive renal insufficiency in methylmalonic acidemia
https://link.springer.com/article/10.1007/BF00867492
Methylmalonic acidemia is a heterogeneous inborn error of propionate metabolism. Therapy frequently includes a low-protein diet to minimize precursors of ...
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https://link.springer.com/article/10.1007/BF00867492
Methylmalonic acidemia is a heterogeneous inborn error of propionate metabolism. Therapy frequently includes a low-protein diet to minimize precursors of ...
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10
Severe renal failure and hyperammonemia in a newborn with ...
https://www.tandfonline.com/doi/full/10.3109/0886022X.2013.865484
Propionic acidemia (PA) is one of the intoxication type organic acidemias which often present with lethargy, poor feeding, and vomiting and can progress to coma ...
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https://www.tandfonline.com/doi/full/10.3109/0886022X.2013.865484
Propionic acidemia (PA) is one of the intoxication type organic acidemias which often present with lethargy, poor feeding, and vomiting and can progress to coma ...
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11
Metabolic Acidosis Treatment & Management
https://emedicine.medscape.com/article/242975-treatment
Hyperkalemia and acidosis worsen as kidney function declines further; eventually, the patient develops a high anion gap renal acidosis. Renal ...
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https://emedicine.medscape.com/article/242975-treatment
Hyperkalemia and acidosis worsen as kidney function declines further; eventually, the patient develops a high anion gap renal acidosis. Renal ...
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12
ORGANIC-ACIDURIA, DECREASED RENAL AMMONIA ...
https://jamanetwork.com/journals/jamapediatrics/fullarticle/495516
The following patients had abnormalities of renal function, bone disease, mental retardation, and congenital glaucoma. This combination appears to be unique ...
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https://jamanetwork.com/journals/jamapediatrics/fullarticle/495516
The following patients had abnormalities of renal function, bone disease, mental retardation, and congenital glaucoma. This combination appears to be unique ...
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13
Practical management of organic acidemias - IOS Press
https://content.iospress.com/articles/translational-science-of-rare-diseases/trd190039
Organic acidemias or acidurias (OAs) are a group of metabolic disorders which result in organic acids detected in the urine (or plasma).
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https://content.iospress.com/articles/translational-science-of-rare-diseases/trd190039
Organic acidemias or acidurias (OAs) are a group of metabolic disorders which result in organic acids detected in the urine (or plasma).
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14
Metabolic Acidosis of CKD: An Update
https://www.ajkd.org/article/S0272-6386(15)01211-1/abstract
Therefore, when kidney function is compromised, a primary reduction in serum bicarbonate concentration can develop. Previously termed uremic ...
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https://www.ajkd.org/article/S0272-6386(15)01211-1/abstract
Therefore, when kidney function is compromised, a primary reduction in serum bicarbonate concentration can develop. Previously termed uremic ...
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15
Metabolic acidosis - Wikipedia
https://en.wikipedia.org/wiki/Metabolic_acidosis
A state of chronic metabolic acidosis, lasting several weeks to years, can be the result of impaired kidney function (chronic kidney disease) and/or ...
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https://en.wikipedia.org/wiki/Metabolic_acidosis
A state of chronic metabolic acidosis, lasting several weeks to years, can be the result of impaired kidney function (chronic kidney disease) and/or ...
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16
Methylmalonic acidemia with emergency hypertension
https://www.revistanefrologia.com/en-methylmalonic-acidemia-with-emergency-hypertension-articulo-S201325141500111X
In the current study, the two mentioned patients had MMA that confirmed with assessment of urine organic acid and acylcarnitine profile. They had just renal ...
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https://www.revistanefrologia.com/en-methylmalonic-acidemia-with-emergency-hypertension-articulo-S201325141500111X
In the current study, the two mentioned patients had MMA that confirmed with assessment of urine organic acid and acylcarnitine profile. They had just renal ...
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17
Metabolic Acidosis - Endocrine and Metabolic Disorders
https://www.merckmanuals.com/professional/endocrine-and-metabolic-disorders/acid-base-regulation-and-disorders/metabolic-acidosis
This can happen in cases of chronic renal failure, in which organic acids such as uric acid or sulfur- containing amino acids can accumulate because they ...
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https://www.merckmanuals.com/professional/endocrine-and-metabolic-disorders/acid-base-regulation-and-disorders/metabolic-acidosis
This can happen in cases of chronic renal failure, in which organic acids such as uric acid or sulfur- containing amino acids can accumulate because they ...
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18
Diagnosing metabolic acidosis in chronic kidney disease
https://www.krcp-ksn.org/journal/view.php?doi=10.23876/j.krcp.21.200
Acidosis with high anion gap frequently develops in later stages of CKD. Therefore, the anion gap is a time-varying factor and renal function ( ...
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https://www.krcp-ksn.org/journal/view.php?doi=10.23876/j.krcp.21.200
Acidosis with high anion gap frequently develops in later stages of CKD. Therefore, the anion gap is a time-varying factor and renal function ( ...
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19
Methylmalonic Acidemia - Acute Illness Protocol
https://www.newenglandconsortium.org/methyl
Renal failure: patients with MMA are particularly susceptible to progressive renal failure from tubulointerstitial nephropathy and, thus, renal function should ...
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https://www.newenglandconsortium.org/methyl
Renal failure: patients with MMA are particularly susceptible to progressive renal failure from tubulointerstitial nephropathy and, thus, renal function should ...
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20
Noninvasive monitoring of chronic kidney disease using pH ...
https://www.science.org/doi/10.1126/sciadv.aaw8357
Organic acidemias represent a group of rare inborn errors of metabolism caused by disturbances primarily of amino acid metabolism that result in large abnormal ...
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https://www.science.org/doi/10.1126/sciadv.aaw8357
Organic acidemias represent a group of rare inborn errors of metabolism caused by disturbances primarily of amino acid metabolism that result in large abnormal ...
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21
Methylmalonic acidemia - UpToDate
https://www.uptodate.com/contents/methylmalonic-acidemia
The genetic causes of MMA are reviewed here. An overview of the presentation, initial evaluation, diagnosis, and management of organic acidemias ...
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https://www.uptodate.com/contents/methylmalonic-acidemia
The genetic causes of MMA are reviewed here. An overview of the presentation, initial evaluation, diagnosis, and management of organic acidemias ...
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22
Renal replacement therapy in the treatment of confirmed or ...
https://www.jpeds.com/article/S0022-3476(06)00005-9/abstract
Eighteen patients underwent 21 renal replacement therapy treatments for metabolic disturbances caused by urea cycle defects (n = 14), organic acidemias (n ...
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https://www.jpeds.com/article/S0022-3476(06)00005-9/abstract
Eighteen patients underwent 21 renal replacement therapy treatments for metabolic disturbances caused by urea cycle defects (n = 14), organic acidemias (n ...
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23
The Kidney Involvement In Inborn Errors Of Metabolism - Neliti
https://media.neliti.com/media/publications/262772-the-kidney-involvement-in-inborn-errors-ceee1501.pdf
lysosomal disorders, organic acidemias, mitochondrial disorders, purine and pyrimidine disorders) ... Kidney diseases (either congenital or acquired) can be.
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https://media.neliti.com/media/publications/262772-the-kidney-involvement-in-inborn-errors-ceee1501.pdf
lysosomal disorders, organic acidemias, mitochondrial disorders, purine and pyrimidine disorders) ... Kidney diseases (either congenital or acquired) can be.
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24
Liver and/or kidney transplantation in amino and organic acid ...
https://oslo-universitetssykehus.no/seksjon/nasjonal-kompetansetjeneste-for-medfodte-stoffskiftesykdommer/PublishingImages/fag-og-forskning/nasjonale-og-regionale-tjenester/nasjonal-kompetansetjeneste-for-medfodte-stoffskiftesykdommer/forskning-og-utvikling/forskning/jimd.12318%20(1).pdf
homocitrullinemia; IEM, inborn errors of metabolism; IVA, isovaleric acidemia; MELD, model for end-stage liver disease; MMA, methylmalonic.
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https://oslo-universitetssykehus.no/seksjon/nasjonal-kompetansetjeneste-for-medfodte-stoffskiftesykdommer/PublishingImages/fag-og-forskning/nasjonale-og-regionale-tjenester/nasjonal-kompetansetjeneste-for-medfodte-stoffskiftesykdommer/forskning-og-utvikling/forskning/jimd.12318%20(1).pdf
homocitrullinemia; IEM, inborn errors of metabolism; IVA, isovaleric acidemia; MELD, model for end-stage liver disease; MMA, methylmalonic.
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25
ORGANIC ACID DISORDERS - WV.gov
https://dhhr.wv.gov/ols/labs/Pages/ORGANICACIDDISORDERS.aspx
ISOVALERIC ACIDEMIA (IVA) ... IVA results from a defect in the metabolism of the amino acid, leucine. There are 2 types of this disorder. The acute neonatal form ...
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https://dhhr.wv.gov/ols/labs/Pages/ORGANICACIDDISORDERS.aspx
ISOVALERIC ACIDEMIA (IVA) ... IVA results from a defect in the metabolism of the amino acid, leucine. There are 2 types of this disorder. The acute neonatal form ...
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26
Renal Tubular Acidosis - VetFolio
https://www.vetfolio.com/learn/article/renal-tubular-acidosis
RTA typically causes metabolic acidosis with both a normal anion gap and normal glomerular filtration rate (GFR). In contrast, renal failure is often associated ...
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https://www.vetfolio.com/learn/article/renal-tubular-acidosis
RTA typically causes metabolic acidosis with both a normal anion gap and normal glomerular filtration rate (GFR). In contrast, renal failure is often associated ...
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27
Acid/Base Disorders: Metabolic Acidosis
https://www.renalandurologynews.com/home/decision-support-in-medicine/nephrology-hypertension/acid-base-disorders-metabolic-acidosis/
Chronic kidney disease with decreased renal function is a common cause of metabolic acidosis. In the early phases with moderate functional decline (stage 3 ...
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https://www.renalandurologynews.com/home/decision-support-in-medicine/nephrology-hypertension/acid-base-disorders-metabolic-acidosis/
Chronic kidney disease with decreased renal function is a common cause of metabolic acidosis. In the early phases with moderate functional decline (stage 3 ...
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28
Renal Tubular Acidosis
https://med.stanford.edu/content/dam/sm/pednephrology/documents/secure/RTA.pdf
family was on dialysis or had kidney diseases except for the ... the diagnosis of renal tubular acidosis. (RTA). ... A. Accumulation of organic acids.
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https://med.stanford.edu/content/dam/sm/pednephrology/documents/secure/RTA.pdf
family was on dialysis or had kidney diseases except for the ... the diagnosis of renal tubular acidosis. (RTA). ... A. Accumulation of organic acids.
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29
Clinical and Laboratory Study of Methylmalonic Acidemia
https://clinicaltrials.gov/ct2/show/NCT00078078
Increasingly, solid organ transplantation (liver, and/or kidney) has been used to treat patients. Disordered transport and intracellular metabolism of vitamin ...
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https://clinicaltrials.gov/ct2/show/NCT00078078
Increasingly, solid organ transplantation (liver, and/or kidney) has been used to treat patients. Disordered transport and intracellular metabolism of vitamin ...
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30
Management of adult-onset - methylmalonic acidemia
https://journals.lww.com/md-journal/Fulltext/2018/06220/Management_of_adult_onset_methylmalonic_acidemia.58.aspx
We report a 26-year-old male who presented with metabolic acidosis, acute renal failure required hemodialysis and acute respiratory failure required ...
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https://journals.lww.com/md-journal/Fulltext/2018/06220/Management_of_adult_onset_methylmalonic_acidemia.58.aspx
We report a 26-year-old male who presented with metabolic acidosis, acute renal failure required hemodialysis and acute respiratory failure required ...
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31
Scientific Updates on Organic Acidemias and Homocystinurias
https://www.youtube.com/watch?v=Ch6j0EAMbsM
National Human Genome Research Institute
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https://www.youtube.com/watch?v=Ch6j0EAMbsM
National Human Genome Research Institute
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32
Organic acid disorders - Annals of Translational Medicine
https://atm.amegroups.com/article/view/23100/html
OA disorders as inborn errors of metabolism (IEM) are included in differential diagnosis of metabolic acidosis, as the common mnemonic MUDPILES taught in ...
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https://atm.amegroups.com/article/view/23100/html
OA disorders as inborn errors of metabolism (IEM) are included in differential diagnosis of metabolic acidosis, as the common mnemonic MUDPILES taught in ...
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33
Drug-induced renal Fanconi syndrome | QJM - Oxford Academic
https://academic.oup.com/qjmed/article/107/4/261/1675347
Unfortunately, by the time patients develop symptoms, bone disease is often quite advanced. Metabolic acidosis in FS is typically mild, with ...
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https://academic.oup.com/qjmed/article/107/4/261/1675347
Unfortunately, by the time patients develop symptoms, bone disease is often quite advanced. Metabolic acidosis in FS is typically mild, with ...
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34
Fanconi syndrome - bionity.com
https://www.bionity.com/en/encyclopedia/Fanconi_syndrome.html
Fanconi Syndrome (also known as Fanconi's syndrome) is a disorder in which the proximal tubular function of the kidney is impaired, resulting in decreased ...
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https://www.bionity.com/en/encyclopedia/Fanconi_syndrome.html
Fanconi Syndrome (also known as Fanconi's syndrome) is a disorder in which the proximal tubular function of the kidney is impaired, resulting in decreased ...
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35
Methylmalonic acidemia - Genetics - MedlinePlus
https://medlineplus.gov/genetics/condition/methylmalonic-acidemia/
Methylmalonic acidemia is an inherited disorder in which the body is unable to process certain proteins and fats (lipids) properly.
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https://medlineplus.gov/genetics/condition/methylmalonic-acidemia/
Methylmalonic acidemia is an inherited disorder in which the body is unable to process certain proteins and fats (lipids) properly.
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36
Inborn Errors of Metabolism (Metabolic Disorders)
https://publications.aap.org/pediatricsinreview/article/37/1/3/34906/Inborn-Errors-of-Metabolism-Metabolic-Disorders
Unlike the organic acidemias, severe metabolic acidosis is not is a prominent finding; some ill patients have mild acidosis related to ...
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https://publications.aap.org/pediatricsinreview/article/37/1/3/34906/Inborn-Errors-of-Metabolism-Metabolic-Disorders
Unlike the organic acidemias, severe metabolic acidosis is not is a prominent finding; some ill patients have mild acidosis related to ...
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37
Chapter 19 - Organic Acidemias of the Newborn
https://www.cambridge.org/core/books/progressive-brain-disorders-in-childhood/organic-acidemias-of-the-newborn/1DE08D6EE92E783295EE7DCACC2DC996
Methylmalonic acidemia, Encephalopathy crises. Epilepsy Dyskinetic movement disorders. Basal ganglia injury (Figure 19.6) Renal failure. Pancreatitis ...
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https://www.cambridge.org/core/books/progressive-brain-disorders-in-childhood/organic-acidemias-of-the-newborn/1DE08D6EE92E783295EE7DCACC2DC996
Methylmalonic acidemia, Encephalopathy crises. Epilepsy Dyskinetic movement disorders. Basal ganglia injury (Figure 19.6) Renal failure. Pancreatitis ...
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38
Neuroimaging Findings of Organic Acidemias and ...
https://pubs.rsna.org/doi/full/10.1148/rg.2018170042
Organic acidemias and aminoacidopathies include a variety of inborn errors of metabolism that are caused by defects in the intermediary ...
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https://pubs.rsna.org/doi/full/10.1148/rg.2018170042
Organic acidemias and aminoacidopathies include a variety of inborn errors of metabolism that are caused by defects in the intermediary ...
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39
Neonatal Presentations of Metabolic Disorders
https://renaissance.stonybrookmedicine.edu/system/files/Neonatal%20Presentations%20of%20Metabolic%20Disorders.pdf
typical in neonates with organic acidemias such as meth- ... mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia.
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https://renaissance.stonybrookmedicine.edu/system/files/Neonatal%20Presentations%20of%20Metabolic%20Disorders.pdf
typical in neonates with organic acidemias such as meth- ... mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia.
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40
Scientific Updates on Organic Acidemias and Homocystinurias
https://www.genome.gov/event-calendar/Scientific-Updates-on-Organic-Acidemias-and-Homocystinurias
Scientific Session: Combined Methylmalonic Acidemia and Homocystinuria ... their functions in the context of kidney homeostasis and disease.
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https://www.genome.gov/event-calendar/Scientific-Updates-on-Organic-Acidemias-and-Homocystinurias
Scientific Session: Combined Methylmalonic Acidemia and Homocystinuria ... their functions in the context of kidney homeostasis and disease.
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41
19 Branched-Chain Organic Acidurias/Acidemias
http://eknygos.lsmuni.lt/springer/223/IV%20Part/245-262.pdf
19.1 · Maple Syrup Urine Disease, Isovaleric Aciduria, Propionic Aciduria, Methylmalonic ... lent, but end-stage renal failure may develop, and dialysis.
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http://eknygos.lsmuni.lt/springer/223/IV%20Part/245-262.pdf
19.1 · Maple Syrup Urine Disease, Isovaleric Aciduria, Propionic Aciduria, Methylmalonic ... lent, but end-stage renal failure may develop, and dialysis.
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42
Metabolic acidosis and progression of chronic kidney disease
https://scielo.isciii.es/pdf/nefrologia/v32n6/revision3.pdf
organic/inorganic acids and the development of tubuloin- ... tween worsening renal function and acidosis in the pre-. ESRD population. PATHOGENESIS.
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https://scielo.isciii.es/pdf/nefrologia/v32n6/revision3.pdf
organic/inorganic acids and the development of tubuloin- ... tween worsening renal function and acidosis in the pre-. ESRD population. PATHOGENESIS.
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43
Proposed guidelines for the diagnosis and management of ...
https://d-nb.info/1098899296/34
Patients with organic acidemias are at risk of osteopenia and osteoporosis [30,31] which is aggravated as a result of renal dysfunction in MMA. The metabolic ...
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https://d-nb.info/1098899296/34
Patients with organic acidemias are at risk of osteopenia and osteoporosis [30,31] which is aggravated as a result of renal dysfunction in MMA. The metabolic ...
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44
Cardiac Complications in Patients with Propionic Acidemia
https://www.rarediseasesjournal.com/articles/cardiac-complications-in-patients-with-propionic-acidemia.html
Propionic acidemia (PA; OMIM #606054) is an inherited autosomal recessive inborn error of the propionate metabolism resulting from propionyl-CoA ...
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https://www.rarediseasesjournal.com/articles/cardiac-complications-in-patients-with-propionic-acidemia.html
Propionic acidemia (PA; OMIM #606054) is an inherited autosomal recessive inborn error of the propionate metabolism resulting from propionyl-CoA ...
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45
Vitamin B12 unresponsive methylmalonic acidemia - Orphanet
https://www.orpha.net/consor/www/cgi-bin/OC_Exp.php?lng=EN&Expert=27
Patients may also show signs of anemia which is not megaloblastic. They may also have potentially life-threatening ketoacidosis and/or hyperammonemia, renal and ...
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https://www.orpha.net/consor/www/cgi-bin/OC_Exp.php?lng=EN&Expert=27
Patients may also show signs of anemia which is not megaloblastic. They may also have potentially life-threatening ketoacidosis and/or hyperammonemia, renal and ...
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46
Metabolic Seizures - Frontiers
https://www.frontiersin.org/articles/10.3389/fneur.2021.640371/full
Metabolic derangements can provide some clues for metabolic diseases including hypoglycemia in fatty acid oxidations defects, metabolic acidosis ...
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https://www.frontiersin.org/articles/10.3389/fneur.2021.640371/full
Metabolic derangements can provide some clues for metabolic diseases including hypoglycemia in fatty acid oxidations defects, metabolic acidosis ...
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47
Metabolic acidosis | Osmosis
https://www.osmosis.org/learn/Metabolic_acidosis
This can happen in cases of chronic renal failure, in which organic acids such as uric acid or sulfur- containing amino acids can accumulate ...
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https://www.osmosis.org/learn/Metabolic_acidosis
This can happen in cases of chronic renal failure, in which organic acids such as uric acid or sulfur- containing amino acids can accumulate ...
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48
Hyperammonaemia with distal renal tubular acidosis
https://adc.bmj.com/content/77/5/441
Hyperammonaemia with metabolic acidosis is often observed in patients with inborn errors of metabolism, such as abnormalities of the urea cycle or organic ...
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https://adc.bmj.com/content/77/5/441
Hyperammonaemia with metabolic acidosis is often observed in patients with inborn errors of metabolism, such as abnormalities of the urea cycle or organic ...
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49
Methylmalonic acidemia: a megamitochondrial disorder ... - Gale
https://go.gale.com/ps/i.do?id=GALE%7CA386212329&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=0931041X&p=AONE&sw=w
Renal tubular dysfunction with progression into chronic tubulointerstitial nephritis and end stage renal disease is a cardinal manifestation of methylmalonic ...
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https://go.gale.com/ps/i.do?id=GALE%7CA386212329&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=0931041X&p=AONE&sw=w
Renal tubular dysfunction with progression into chronic tubulointerstitial nephritis and end stage renal disease is a cardinal manifestation of methylmalonic ...
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50
FGF21 underlies a hormetic response to metabolic stress in ...
https://insight.jci.org/articles/view/124351
Methylmalonic acidemia (MMA), an organic acidemia characterized by ... Organic acidemias, along with maple syrup urine disease and urea ...
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https://insight.jci.org/articles/view/124351
Methylmalonic acidemia (MMA), an organic acidemia characterized by ... Organic acidemias, along with maple syrup urine disease and urea ...
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51
ACVIM 2008 - VIN
https://www.vin.com/apputil/content/defaultadv1.aspx?pId=11262&catId=32593&id=3865688&ind=732&objTypeID=17
Acid-base status is usually well preserved in chronic renal failure until GFR falls to 10 to 20% of normal. Classically, metabolic acidosis in chronic renal ...
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https://www.vin.com/apputil/content/defaultadv1.aspx?pId=11262&catId=32593&id=3865688&ind=732&objTypeID=17
Acid-base status is usually well preserved in chronic renal failure until GFR falls to 10 to 20% of normal. Classically, metabolic acidosis in chronic renal ...
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52
The Case | A woman with severe metabolic acidosis
https://www.kidney-international.org/article/S0085-2538(15)54225-7/pdf
had history of chronic renal failure and perforated peptic ... metabolic acidosis refractory to intravenous sodium bicarbonate. ... Organic acids production.
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https://www.kidney-international.org/article/S0085-2538(15)54225-7/pdf
had history of chronic renal failure and perforated peptic ... metabolic acidosis refractory to intravenous sodium bicarbonate. ... Organic acids production.
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53
Investigations of Methylmalonic Acidemia and Related Disorders
https://grantome.com/grant/NIH/ZIA-HG200318-16
In the last year, our studies of the NIH PA cohort has allowed new insights into the natural history of kidney disease in propionic acidemia.
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https://grantome.com/grant/NIH/ZIA-HG200318-16
In the last year, our studies of the NIH PA cohort has allowed new insights into the natural history of kidney disease in propionic acidemia.
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54
Nutritional Management and Biochemical Outcomes during ...
https://www.mdpi.com/2072-6643/12/10/2976/htm
Methylmalonic acidemia (MMA) (OMIM: 251000) is an organic acidemia caused by pathogenic variants in the MMUT gene encoding the enzyme, methyl-malonyl-CoA mutase ...
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https://www.mdpi.com/2072-6643/12/10/2976/htm
Methylmalonic acidemia (MMA) (OMIM: 251000) is an organic acidemia caused by pathogenic variants in the MMUT gene encoding the enzyme, methyl-malonyl-CoA mutase ...
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55
High Anion Gap Metabolic Acidosis Article - StatPearls
https://www.statpearls.com/ArticleLibrary/viewarticle/22866
However, in patients with abnormal levels of albumin this must be corrected. ... Aspirin (salicylic acid); Renal Failure (uremic acidosis) ...
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https://www.statpearls.com/ArticleLibrary/viewarticle/22866
However, in patients with abnormal levels of albumin this must be corrected. ... Aspirin (salicylic acid); Renal Failure (uremic acidosis) ...
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56
Targeting proximal tubule mitochondrial dysfunction ... - jstor
https://www.jstor.org/stable/42712945
Isolated methylmalonic acidemia (MMA), caused by deficiency of ... cobalamin | chronic renal failure | megamitochondria | organic acidemia.
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https://www.jstor.org/stable/42712945
Isolated methylmalonic acidemia (MMA), caused by deficiency of ... cobalamin | chronic renal failure | megamitochondria | organic acidemia.
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57
Inborn Errors of Metabolism: From Preconception to Adulthood
https://www.aafp.org/content/dam/brand/aafp/pubs/afp/issues/2019/0101/p25.pdf
Liver and renal failure after start of milk feeds in first week of life ... Urea cycle disorders, organic acidemias. Arterial/venous gas.
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https://www.aafp.org/content/dam/brand/aafp/pubs/afp/issues/2019/0101/p25.pdf
Liver and renal failure after start of milk feeds in first week of life ... Urea cycle disorders, organic acidemias. Arterial/venous gas.
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58
Metabolic Acidosis | Choose the Right Test - ARUP Consult
https://arupconsult.com/content/metabolic-acidosis
Ethanol poisoning. High. Sulfuric, phosphoric, organic. Renal failure ; Ethylene glycol poisoning. High. Oxalic acid, glycine, oxalomalic acid, formic acid.
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https://arupconsult.com/content/metabolic-acidosis
Ethanol poisoning. High. Sulfuric, phosphoric, organic. Renal failure ; Ethylene glycol poisoning. High. Oxalic acid, glycine, oxalomalic acid, formic acid.
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59
Novel Insights into the Pathophysiology of Kidney Disease in ...
https://www.zora.uzh.ch/id/eprint/148531/1/Thesis_Anke_Schumann_Approved_Print_version.pdf
MMA clinically results in severe metabolic acidosis due to accumulation of organic acids (predominantly methylmalonic acid), hyper-ammonaemia and an acute, life ...
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https://www.zora.uzh.ch/id/eprint/148531/1/Thesis_Anke_Schumann_Approved_Print_version.pdf
MMA clinically results in severe metabolic acidosis due to accumulation of organic acids (predominantly methylmalonic acid), hyper-ammonaemia and an acute, life ...
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60
Methylmalonic acidemia, cblB type - Myriad Genetics
https://myriad.com/womens-health/diseases/methylmalonic-acidemia-cblb-type/
Even with treatment, the cblB type can be associated with symptoms, like intellectual disability or kidney failure. Metabolic crisis can lead to coma, ...
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https://myriad.com/womens-health/diseases/methylmalonic-acidemia-cblb-type/
Even with treatment, the cblB type can be associated with symptoms, like intellectual disability or kidney failure. Metabolic crisis can lead to coma, ...
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61
Kidney transplantation in a girl with methylmalonic acidemia ...
http://www.nuovarmonia.it/wp-content/uploads/2014/01/4670848def.pdf
Abstract Methylmalonic acidemia (MMA) is an inborn error of organic acid metabolism that occurs in infancy with hypotonia, vomiting, dehydration, ...
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http://www.nuovarmonia.it/wp-content/uploads/2014/01/4670848def.pdf
Abstract Methylmalonic acidemia (MMA) is an inborn error of organic acid metabolism that occurs in infancy with hypotonia, vomiting, dehydration, ...
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62
Automobile Paint Reducer Induced Acute Kidney Injury
https://jrenhep.com/index.php/jrenhep/article/download/116/237/1499
Organic solvents can also result in liver injury and rhabdomyolysis. Some risk factors that suggest poor outcomes include altered mental status, renal failure ...
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https://jrenhep.com/index.php/jrenhep/article/download/116/237/1499
Organic solvents can also result in liver injury and rhabdomyolysis. Some risk factors that suggest poor outcomes include altered mental status, renal failure ...
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63
Organic Acidemias | Pediatrics Clerkship
https://pedclerk.bsd.uchicago.edu/page/organic-acidemias
Most organic acidemias are inherited in an autosomal recessive fashion, though some X-linked forms have been described. Afflicted children experience severe ...
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https://pedclerk.bsd.uchicago.edu/page/organic-acidemias
Most organic acidemias are inherited in an autosomal recessive fashion, though some X-linked forms have been described. Afflicted children experience severe ...
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64
Organic Acid Metabolic Disorders
https://med.unr.edu/nsphl/newborn-screening/disorders/organic-acid-metabolic-disorders
Problems with one or more of these enzymes can cause an organic acid disorder. People with organic acid disorders cannot break down protein properly. This ...
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https://med.unr.edu/nsphl/newborn-screening/disorders/organic-acid-metabolic-disorders
Problems with one or more of these enzymes can cause an organic acid disorder. People with organic acid disorders cannot break down protein properly. This ...
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65
Disorders of branched-chain amino acid metabolism
https://www.cancertherapyadvisor.com/home/decision-support-in-medicine/pediatrics/disorders-of-branched-chain-amino-acid-metabolism/
Other complications of metabolic decompensation in organic acidemias can include cardiomyopathy, pancreatitis, and renal failure. Although these complications ...
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https://www.cancertherapyadvisor.com/home/decision-support-in-medicine/pediatrics/disorders-of-branched-chain-amino-acid-metabolism/
Other complications of metabolic decompensation in organic acidemias can include cardiomyopathy, pancreatitis, and renal failure. Although these complications ...
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66
Organic Acidemia disease - MalaCards
http://www.malacards.org/card/organic_acidemia
Disease Ontology : An amino acid metabolic disorder that disrupts normal amino acid metabolism causing a building up of branched-chain amino ...
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http://www.malacards.org/card/organic_acidemia
Disease Ontology : An amino acid metabolic disorder that disrupts normal amino acid metabolism causing a building up of branched-chain amino ...
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67
Organic Acidemias - ResearchGate
https://www.researchgate.net/publication/361311581_Organic_Acidemias
Outcomes in PROP and MMA have been guarded with frequent neurological complications, renal dysfunction, cardiomyopathy and optic atrophy but are improving ...
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https://www.researchgate.net/publication/361311581_Organic_Acidemias
Outcomes in PROP and MMA have been guarded with frequent neurological complications, renal dysfunction, cardiomyopathy and optic atrophy but are improving ...
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68
Organic acidemias: An overview and specific defects - medilib
https://www.medilib.ir/uptodate/show/2927
INTRODUCTION — Organic acidemias, also known as organic acidurias, are a class of inborn errors of metabolism characterized by accumulation ...
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https://www.medilib.ir/uptodate/show/2927
INTRODUCTION — Organic acidemias, also known as organic acidurias, are a class of inborn errors of metabolism characterized by accumulation ...
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69
What Are Organic Acidemias?
https://oaanews.org/about/what-are-organic-acidemias/
What Are Organic Acidemias? Organic Acidaemias are a group of inheritable genetic metabolic disorders in which there is a defect in protein metabolism where ...
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https://oaanews.org/about/what-are-organic-acidemias/
What Are Organic Acidemias? Organic Acidaemias are a group of inheritable genetic metabolic disorders in which there is a defect in protein metabolism where ...
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70
Organic acidemia - MediGoo - Health Medical Tests and Free ...
https://www.medigoo.com/articles/organic-acidemia/
The term "organic acidemia" applies to a group of disorders characterized by the excretion of non-amino organic acids in urine. Most organic acidemias result ...
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https://www.medigoo.com/articles/organic-acidemia/
The term "organic acidemia" applies to a group of disorders characterized by the excretion of non-amino organic acids in urine. Most organic acidemias result ...
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71
95: The Organic Acidemias - Basicmedical Key
https://basicmedicalkey.com/95-the-organic-acidemias/
Disease summary: Organic acidemias are disorders of intermediary metabolism of one or more amino acid constituents of protein, due to a deficiency of an ...
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https://basicmedicalkey.com/95-the-organic-acidemias/
Disease summary: Organic acidemias are disorders of intermediary metabolism of one or more amino acid constituents of protein, due to a deficiency of an ...
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72
Organic Acidemias | Encyclopedia.com
https://www.encyclopedia.com/science/encyclopedias-almanacs-transcripts-and-maps/organic-acidemias
Organic acidemiasDefinitionOrganic acidemias are a collection of amino and fatty acid oxidation disorders that cause non-amino organic acids to accumulate ...
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https://www.encyclopedia.com/science/encyclopedias-almanacs-transcripts-and-maps/organic-acidemias
Organic acidemiasDefinitionOrganic acidemias are a collection of amino and fatty acid oxidation disorders that cause non-amino organic acids to accumulate ...
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73
Renal Tubular Acidosis and Uraemic Acidosis - LITFL.com
https://litfl.com/renal-tubular-acidosis-and-uraemic-acidosis/
involves injury to glomeruli and tubules · decreased glomerular filtration rate (GFR) (e.g. <20 mL/min) · failure to excrete acid anions · accumulation of acidic ...
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https://litfl.com/renal-tubular-acidosis-and-uraemic-acidosis/
involves injury to glomeruli and tubules · decreased glomerular filtration rate (GFR) (e.g. <20 mL/min) · failure to excrete acid anions · accumulation of acidic ...
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74
Organic Acid Disorders - Newborn Screening Program - IDPH
http://www.idph.state.il.us/HealthWellness/fs/organic.htm
Each organic acid disorder is associated with a specific enzyme deficiency that causes the accumulation of organic acids in blood and urine. The accumulated ...
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http://www.idph.state.il.us/HealthWellness/fs/organic.htm
Each organic acid disorder is associated with a specific enzyme deficiency that causes the accumulation of organic acids in blood and urine. The accumulated ...
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75
Kirk's Current Veterinary Therapy XV - Page 7 - Google Books Result
https://books.google.com/books?id=KlJKAgAAQBAJ&pg=RA1-PA7&lpg=RA1-PA7&dq=organic+acidemia+renal+failure&source=bl&ots=XzHw96h4cd&sig=ACfU3U2TkrhmVp-v3mQRvHXaMIiiZgz1wA&hl=en&sa=X&ved=2ahUKEwj_v5XVn7_7AhXWEVkFHdW5Dt0Q6AF6BQivAhAD
... Total parenteral nutrition • Chloride retention • Renal failure • Hypoadrenocorticism Organic Acidosis (↑ Unmeasured Strong Anions) • Uremic acidosis ...
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https://books.google.com/books?id=KlJKAgAAQBAJ&pg=RA1-PA7&lpg=RA1-PA7&dq=organic+acidemia+renal+failure&source=bl&ots=XzHw96h4cd&sig=ACfU3U2TkrhmVp-v3mQRvHXaMIiiZgz1wA&hl=en&sa=X&ved=2ahUKEwj_v5XVn7_7AhXWEVkFHdW5Dt0Q6AF6BQivAhAD
... Total parenteral nutrition • Chloride retention • Renal failure • Hypoadrenocorticism Organic Acidosis (↑ Unmeasured Strong Anions) • Uremic acidosis ...
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76
ketoacidosis causes - World Finance Forum
https://worldfinanceforum.it/ketoacidosis-causes.html
Additional tests Aug 08, 2022 · Alcoholic ketoacidosis occurs in patients ... of distal renal tubular acidosis in DKA include interstitial renal disease, ...
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https://worldfinanceforum.it/ketoacidosis-causes.html
Additional tests Aug 08, 2022 · Alcoholic ketoacidosis occurs in patients ... of distal renal tubular acidosis in DKA include interstitial renal disease, ...
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77
Kidney Failure Taming the Rogue Kidneys Vital Information
https://yaronmargolin.com/?p=13099
This includes avoiding accelerated sports activity to prevent complications that include lactic acid build-up that causes blood acidosis, and ...
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https://yaronmargolin.com/?p=13099
This includes avoiding accelerated sports activity to prevent complications that include lactic acid build-up that causes blood acidosis, and ...
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78
Chronic Kidney Disease Progression | Metabolic Acidosis
https://www.metabolicacidosisinsights.com/ckd-progression
Metabolic acidosis was shown to be an independent predictor of adverse renal outcomes ... In a longitudinal analysis in over 51,000 patients with non-dialysis ...
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https://www.metabolicacidosisinsights.com/ckd-progression
Metabolic acidosis was shown to be an independent predictor of adverse renal outcomes ... In a longitudinal analysis in over 51,000 patients with non-dialysis ...
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79
Organic acidemia - wikidoc
https://www.wikidoc.org/index.php/Organic_acidemia
Organic acidemia, also called organic aciduria, is a term used to classify a group of metabolic disorders which disrupt normal amino acid ...
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https://www.wikidoc.org/index.php/Organic_acidemia
Organic acidemia, also called organic aciduria, is a term used to classify a group of metabolic disorders which disrupt normal amino acid ...
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80
organic acidemias - Humpath.com - Human pathology
https://www.humpath.com/spip.php?article5902
Definition: Organic acidemia, also called organic aciduria, is a term used to classify a group of metabolic disorders which disrupt normal ...
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https://www.humpath.com/spip.php?article5902
Definition: Organic acidemia, also called organic aciduria, is a term used to classify a group of metabolic disorders which disrupt normal ...
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81
Nutrition Management of Inherited Metabolic Diseases: ...
https://books.google.com/books?id=q1LMCQAAQBAJ&pg=PA198&lpg=PA198&dq=organic+acidemia+renal+failure&source=bl&ots=pjOHpAiGJT&sig=ACfU3U2CkRMnuEEmEDUC-RxaDFCzjxP9JA&hl=en&sa=X&ved=2ahUKEwj_v5XVn7_7AhXWEVkFHdW5Dt0Q6AF6BQi7AhAD
Neurodegeneration and chronic renal failure in methylmalonic aciduria–a pathophysiological approach. J Inherit Metab Dis. 2008;31(1): 35–43.
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https://books.google.com/books?id=q1LMCQAAQBAJ&pg=PA198&lpg=PA198&dq=organic+acidemia+renal+failure&source=bl&ots=pjOHpAiGJT&sig=ACfU3U2CkRMnuEEmEDUC-RxaDFCzjxP9JA&hl=en&sa=X&ved=2ahUKEwj_v5XVn7_7AhXWEVkFHdW5Dt0Q6AF6BQi7AhAD
Neurodegeneration and chronic renal failure in methylmalonic aciduria–a pathophysiological approach. J Inherit Metab Dis. 2008;31(1): 35–43.
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82
In a Page Pediatrics - Page 288 - Google Books Result
https://books.google.com/books?id=WPiubP3JgsUC&pg=PA288&lpg=PA288&dq=organic+acidemia+renal+failure&source=bl&ots=tgQC6fbhO_&sig=ACfU3U3aD7_Iw4Hgir-Lkud1I9ad4aSjNA&hl=en&sa=X&ved=2ahUKEwj_v5XVn7_7AhXWEVkFHdW5Dt0Q6AF6BQiwAhAD
... as differential diagnosis for chronic renal failure , 56 for nephrotic ... diagnosis for metabolic acidosis , 251 for organic acidemia , 200 Renal tumor ...
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https://books.google.com/books?id=WPiubP3JgsUC&pg=PA288&lpg=PA288&dq=organic+acidemia+renal+failure&source=bl&ots=tgQC6fbhO_&sig=ACfU3U3aD7_Iw4Hgir-Lkud1I9ad4aSjNA&hl=en&sa=X&ved=2ahUKEwj_v5XVn7_7AhXWEVkFHdW5Dt0Q6AF6BQiwAhAD
... as differential diagnosis for chronic renal failure , 56 for nephrotic ... diagnosis for metabolic acidosis , 251 for organic acidemia , 200 Renal tumor ...
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83
Kirk's Current Veterinary Therapy XIV - E-Book
https://books.google.com/books?id=NaamlrzbTwoC&pg=PA60&lpg=PA60&dq=organic+acidemia+renal+failure&source=bl&ots=JOmYpRsA51&sig=ACfU3U3O_CgEPoRymkkzEdIXc2Xm0cuYXQ&hl=en&sa=X&ved=2ahUKEwj_v5XVn7_7AhXWEVkFHdW5Dt0Q6AF6BQitAhAD
SID Acidosis Three general mechanisms can cause SID to decrease, resulting in ... Chloride retention • Renal failure • Hypoadrenocorticism Organic Acidosis ...
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https://books.google.com/books?id=NaamlrzbTwoC&pg=PA60&lpg=PA60&dq=organic+acidemia+renal+failure&source=bl&ots=JOmYpRsA51&sig=ACfU3U3O_CgEPoRymkkzEdIXc2Xm0cuYXQ&hl=en&sa=X&ved=2ahUKEwj_v5XVn7_7AhXWEVkFHdW5Dt0Q6AF6BQitAhAD
SID Acidosis Three general mechanisms can cause SID to decrease, resulting in ... Chloride retention • Renal failure • Hypoadrenocorticism Organic Acidosis ...
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84
About propionic acidemia (PA) and methylmalonic ... - Carbaglu
https://www.carbaglu.com/hcp/about-propionic-acidemia-and-methylmalonic-acidemia/
Acute hyperammonemia can occur during metabolic decompensation in some PA and MMA patients as a result of a secondary deficiency of the urea cycle enzyme N- ...
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https://www.carbaglu.com/hcp/about-propionic-acidemia-and-methylmalonic-acidemia/
Acute hyperammonemia can occur during metabolic decompensation in some PA and MMA patients as a result of a secondary deficiency of the urea cycle enzyme N- ...
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85
Practical Algorithms in Pediatric Nephrology
https://books.google.com/books?id=xuJPCpr2e-MC&pg=PA83&lpg=PA83&dq=organic+acidemia+renal+failure&source=bl&ots=pzBDMq3vUF&sig=ACfU3U1gEqQNiqnI3YSCE4Y_tkdkj5U58Q&hl=en&sa=X&ved=2ahUKEwj_v5XVn7_7AhXWEVkFHdW5Dt0Q6AF6BQisAhAD
In organic acidemia (lactic acidosis, ketoacidosis, hereditary organic ... Hyperkalemia develops in oliguric acute renal failure even in the absence of ...
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https://books.google.com/books?id=xuJPCpr2e-MC&pg=PA83&lpg=PA83&dq=organic+acidemia+renal+failure&source=bl&ots=pzBDMq3vUF&sig=ACfU3U1gEqQNiqnI3YSCE4Y_tkdkj5U58Q&hl=en&sa=X&ved=2ahUKEwj_v5XVn7_7AhXWEVkFHdW5Dt0Q6AF6BQisAhAD
In organic acidemia (lactic acidosis, ketoacidosis, hereditary organic ... Hyperkalemia develops in oliguric acute renal failure even in the absence of ...
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86
Clinical Manifestations of Organic Acidemia - SBMU Journals
https://journals.sbmu.ac.ir/ijcn/article/view/2897
DescriptionThe term “organic acidemia” or “organic aciduria” (OA) applies to a diverse group of metabolic disorders characterized by the ...
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https://journals.sbmu.ac.ir/ijcn/article/view/2897
DescriptionThe term “organic acidemia” or “organic aciduria” (OA) applies to a diverse group of metabolic disorders characterized by the ...
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87
Denver Medical Times: Utah Medical Journal. Nevada Medicine
https://books.google.com/books?id=39xXAAAAMAAJ&pg=PA497&lpg=PA497&dq=organic+acidemia+renal+failure&source=bl&ots=07cK08Wc14&sig=ACfU3U3k5khCx-g9wxOjNCZnhm4gCG6zww&hl=en&sa=X&ved=2ahUKEwj_v5XVn7_7AhXWEVkFHdW5Dt0Q6AF6BQiuAhAD
The great arthritic group including goutor uric acidemia , obesity and ... Functional and organic renal diseases play a large part , both as cause and as ...
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https://books.google.com/books?id=39xXAAAAMAAJ&pg=PA497&lpg=PA497&dq=organic+acidemia+renal+failure&source=bl&ots=07cK08Wc14&sig=ACfU3U3k5khCx-g9wxOjNCZnhm4gCG6zww&hl=en&sa=X&ved=2ahUKEwj_v5XVn7_7AhXWEVkFHdW5Dt0Q6AF6BQiuAhAD
The great arthritic group including goutor uric acidemia , obesity and ... Functional and organic renal diseases play a large part , both as cause and as ...
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