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Google Keyword Rankings for : sulindac colon cancer
1
Sulindac plus a phospholipid is effective for polyp reduction ...
https://bmccancer.biomedcentral.com/articles/10.1186/s12885-020-07311-4
Non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin and sulindac are effective for colorectal cancer prevention in humans and ...
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https://bmccancer.biomedcentral.com/articles/10.1186/s12885-020-07311-4
Non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin and sulindac are effective for colorectal cancer prevention in humans and ...
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2
The efficacy and safety of sulindac for colorectal polyps
https://journals.lww.com/md-journal/fulltext/2020/10090/the_efficacy_and_safety_of_sulindac_for_colorectal.22.aspx
Long-term maintenance therapy with sulindac can reduce the number of residual colorectal adenomas, the degree of heteromorphism and the ...
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https://journals.lww.com/md-journal/fulltext/2020/10090/the_efficacy_and_safety_of_sulindac_for_colorectal.22.aspx
Long-term maintenance therapy with sulindac can reduce the number of residual colorectal adenomas, the degree of heteromorphism and the ...
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3
Eflornithine and Sulindac in Preventing ... - Clinical Trials
https://clinicaltrials.gov/ct2/show/NCT00118365
Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps · History of >= 1 surgically resected adenomatous polyp of the colon ...
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https://clinicaltrials.gov/ct2/show/NCT00118365
Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps · History of >= 1 surgically resected adenomatous polyp of the colon ...
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4
Sulindac Enhances the Killing of Cancer Cells Exposed to ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005804
The anti-tumorigenic activity of sulindac against colon cancer may involve both COX inhibition [2] and activities that are independent of COX ...
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005804
The anti-tumorigenic activity of sulindac against colon cancer may involve both COX inhibition [2] and activities that are independent of COX ...
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5
Treatment of Colonic and Rectal Adenomas with Sulindac in ...
https://www.nejm.org/doi/full/10.1056/nejm199305063281805
Sulindac reduces the number and size of colorectal adenomas in patients with familial adenomatous polyposis, but its effect is incomplete, and ...
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https://www.nejm.org/doi/full/10.1056/nejm199305063281805
Sulindac reduces the number and size of colorectal adenomas in patients with familial adenomatous polyposis, but its effect is incomplete, and ...
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6
Sulindac Inhibits Growth of Rat Colon Carcinoma by Inducing ...
https://www.karger.com/Article/Fulltext/8780
Sulindac possesses an inhibitory effect on colorectal cancer development. Rat colon cancer cells, ACL-15, inoculated subcutaneously in F344 ...
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https://www.karger.com/Article/Fulltext/8780
Sulindac possesses an inhibitory effect on colorectal cancer development. Rat colon cancer cells, ACL-15, inoculated subcutaneously in F344 ...
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7
Drug Combo Decreases Colorectal Polyps in People with FAP
https://www.cancer.gov/news-events/cancer-currents-blog/2018/fap-erlotinib-sulindac-colorectal-polyps
In people with familial adenomatous polyposis, or FAP, a combination treatment of erlotinib (Tarceva) and sulindac (Aflodac) decreased the ...
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https://www.cancer.gov/news-events/cancer-currents-blog/2018/fap-erlotinib-sulindac-colorectal-polyps
In people with familial adenomatous polyposis, or FAP, a combination treatment of erlotinib (Tarceva) and sulindac (Aflodac) decreased the ...
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8
Sulindac Slows Growth of Colon Polyps, May Prevent Colon ...
https://www.cancernetwork.com/view/sulindac-slows-growth-colon-polyps-may-prevent-colon-cancer
Sulindac sulfone, a nonsteroidal anti-inflammatory drug (NSAID) recently tested in the laboratories of the Arizona Cancer Center, may prove ...
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https://www.cancernetwork.com/view/sulindac-slows-growth-colon-polyps-may-prevent-colon-cancer
Sulindac sulfone, a nonsteroidal anti-inflammatory drug (NSAID) recently tested in the laboratories of the Arizona Cancer Center, may prove ...
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9
Association of Sulindac and Erlotinib vs Placebo With ...
https://jamanetwork.com/journals/jamaoncology/fullarticle/2671609
Importance Patients with familial adenomatous polyposis (FAP) are at markedly increased risk for colorectal polyps and cancer.
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https://jamanetwork.com/journals/jamaoncology/fullarticle/2671609
Importance Patients with familial adenomatous polyposis (FAP) are at markedly increased risk for colorectal polyps and cancer.
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10
NSAIDs (including aspirin): Role in prevention of colorectal ...
https://www.uptodate.com/contents/nsaids-including-aspirin-role-in-prevention-of-colorectal-cancer
Colorectal cancer ranks among the most common malignancies in the United States and ... Difluoromethylornithine plus sulindac for the prevention of sporadic ...
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https://www.uptodate.com/contents/nsaids-including-aspirin-role-in-prevention-of-colorectal-cancer
Colorectal cancer ranks among the most common malignancies in the United States and ... Difluoromethylornithine plus sulindac for the prevention of sporadic ...
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11
Sulindac reversal of 15-PGDH-mediated resistance to colon ...
https://academic.oup.com/carcin/article/36/2/291/334295
Notably, colon tumor prevention activity by sulindac was accompanied by a marked induction of lymphoid aggregates and proximal colonic inflammatory mass lesions ...
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https://academic.oup.com/carcin/article/36/2/291/334295
Notably, colon tumor prevention activity by sulindac was accompanied by a marked induction of lymphoid aggregates and proximal colonic inflammatory mass lesions ...
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12
Sulindac Sulfide, but Not Sulindac Sulfone, Inhibits Colorectal ...
https://www.sciencedirect.com/science/article/pii/S147655869980058X
Sulindac sulfide, a metabolite of the nonsteroidal antiinflammatory drug (NSAID) sulindac sulfoxide, is effective at reducing tumor burden in both familial ...
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https://www.sciencedirect.com/science/article/pii/S147655869980058X
Sulindac sulfide, a metabolite of the nonsteroidal antiinflammatory drug (NSAID) sulindac sulfoxide, is effective at reducing tumor burden in both familial ...
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13
Lovastatin augments sulindac-induced apoptosis in colon ...
https://www.gastrojournal.org/article/S0016-5085(99)70342-2/abstract
NSAIDs are associated with reduced colon cancer incidence, predominantly by increasing apoptosis. We showed previously that lovastatin induces apoptosis in ...
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https://www.gastrojournal.org/article/S0016-5085(99)70342-2/abstract
NSAIDs are associated with reduced colon cancer incidence, predominantly by increasing apoptosis. We showed previously that lovastatin induces apoptosis in ...
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14
Drug Combination Decreases Recurrence Rate of Colon Polyps
https://news.cancerconnect.com/rectal-cancer/drug-combination-decreases-recurrence-rate-of-colon-polyps
Treatment of Stage I - III Colon Cancer ... The researchers concluded that treatment with DFMO/sulindac appears to drastically reduce rates of adenoma recurrence ...
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https://news.cancerconnect.com/rectal-cancer/drug-combination-decreases-recurrence-rate-of-colon-polyps
Treatment of Stage I - III Colon Cancer ... The researchers concluded that treatment with DFMO/sulindac appears to drastically reduce rates of adenoma recurrence ...
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15
Sulindac in Managing Familial Adenomatous Polyposis - AAFP
https://www.aafp.org/pubs/afp/issues/2002/0715/p320.html
Sulindac, a nonsteroidal anti-inflammatory drug, has been found to reduce the size and quantity of rectal adenomatous polyps. Cruz-Correa and ...
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https://www.aafp.org/pubs/afp/issues/2002/0715/p320.html
Sulindac, a nonsteroidal anti-inflammatory drug, has been found to reduce the size and quantity of rectal adenomatous polyps. Cruz-Correa and ...
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16
Sulindac targets nuclear β-catenin accumulation and Wnt ...
https://www.nature.com/articles/6601505
Nonsteroidal anti-inflammatory drugs (NSAIDs) have chemopreventive potential against colorectal carcinomas (CRCs).
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https://www.nature.com/articles/6601505
Nonsteroidal anti-inflammatory drugs (NSAIDs) have chemopreventive potential against colorectal carcinomas (CRCs).
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17
Differential preventive activity of sulindac and atorvastatin in ...
https://gut.bmj.com/content/67/7/1290
Tissues were collected from mice treated for 14 weeks (histopathology) or 7 days (gene expression). Cell cycle analyses were performed on SW480 colon carcinoma ...
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https://gut.bmj.com/content/67/7/1290
Tissues were collected from mice treated for 14 weeks (histopathology) or 7 days (gene expression). Cell cycle analyses were performed on SW480 colon carcinoma ...
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18
Sulindac reversal of 15-PGDH-mediated resistance to ... - VIVO
https://vivo.weill.cornell.edu/display/pubid25503930
These findings suggest that sulindac may be the most effective agent for colon cancer prevention in humans with low 15-PGDH, but its use may ...
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https://vivo.weill.cornell.edu/display/pubid25503930
These findings suggest that sulindac may be the most effective agent for colon cancer prevention in humans with low 15-PGDH, but its use may ...
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19
Sulindac and its metabolites induce carcinogen metabolizing ...
https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.23218
Among the most effective types of preventive agents against colorectal cancer are the nonsteroidal antiinflammatory drugs (NSAIDs).2 In addition ...
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https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.23218
Among the most effective types of preventive agents against colorectal cancer are the nonsteroidal antiinflammatory drugs (NSAIDs).2 In addition ...
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20
Sulindac treatment in hereditary non-polyposis colorectal cancer
https://www.ejcancer.com/article/S0959-8049(07)00197-9/fulltext
Sulindac induces an increase in epithelial cell proliferation in the proximal colon of subjects with HNPCC. Since colorectal cancer predominantly arises in the ...
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https://www.ejcancer.com/article/S0959-8049(07)00197-9/fulltext
Sulindac induces an increase in epithelial cell proliferation in the proximal colon of subjects with HNPCC. Since colorectal cancer predominantly arises in the ...
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21
Selective anti-cancer activity of sulindac derivatives on KRAS ...
https://grantome.com/grant/NIH/R01-CA131378-08S1
We recently discovered that PDE10 is a critically important target of sulindac, which is elevated in colon tumors and essential for tumor cell growth.
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https://grantome.com/grant/NIH/R01-CA131378-08S1
We recently discovered that PDE10 is a critically important target of sulindac, which is elevated in colon tumors and essential for tumor cell growth.
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22
Chemoprevention Strategies Using NSAIDs and COX-2 ...
https://www.tandfonline.com/doi/pdf/10.4161/cbt.214
The effect of sulindac and celecoxib against colorectal adenomas is incomplete and data showing chemoprevention of colorectal carcinoma in FAP are not available ...
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https://www.tandfonline.com/doi/pdf/10.4161/cbt.214
The effect of sulindac and celecoxib against colorectal adenomas is incomplete and data showing chemoprevention of colorectal carcinoma in FAP are not available ...
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23
PACES trial: Evaluating the effectiveness of eflornithine and ...
https://bulletin.facs.org/2015/08/paces-trial-evaluating-the-effectiveness-of-eflornithine-and-sulindac-in-preventing-colon-adenomas/
The S0820 Preventing Adenomas of the Colon with Eflornithine and Sulindac (PACES) study seeks to determine whether two drugs that have shown ...
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https://bulletin.facs.org/2015/08/paces-trial-evaluating-the-effectiveness-of-eflornithine-and-sulindac-in-preventing-colon-adenomas/
The S0820 Preventing Adenomas of the Colon with Eflornithine and Sulindac (PACES) study seeks to determine whether two drugs that have shown ...
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24
Eflornithine and/or Sulindac in Preventing Recurrence of High ...
https://www.georgiacancerinfo.org/clinical-trials/detail/3280
Eflornithine and/or Sulindac in Preventing Recurrence of High-Risk Adenomas and Second Primary Disease in Patients with Stage 0-III Colon or Rectal Cancer.
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https://www.georgiacancerinfo.org/clinical-trials/detail/3280
Eflornithine and/or Sulindac in Preventing Recurrence of High-Risk Adenomas and Second Primary Disease in Patients with Stage 0-III Colon or Rectal Cancer.
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25
Gastroenterology OXT-328.pdf - Stony Brook School of Medicine
https://renaissance.stonybrookmedicine.edu/sites/default/files/Gastroenterology%20OXT-328.pdf
Here, we report the enhanced potency of P-S over sulindac in inhibiting the growth of human colon cancer cell lines, its efficacy in animal tumor models, its ...
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https://renaissance.stonybrookmedicine.edu/sites/default/files/Gastroenterology%20OXT-328.pdf
Here, we report the enhanced potency of P-S over sulindac in inhibiting the growth of human colon cancer cell lines, its efficacy in animal tumor models, its ...
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26
The impact of anti-inflammatory drug sulindac on obesity ...
https://cdr.lib.unc.edu/concern/honors_theses/9s161b223
Our findings indicate that research regarding the effects of NSAID treatment on colon cancer risk and/or progression in obese patients is warranted, especially ...
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https://cdr.lib.unc.edu/concern/honors_theses/9s161b223
Our findings indicate that research regarding the effects of NSAID treatment on colon cancer risk and/or progression in obese patients is warranted, especially ...
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27
Phase 3 Study Tests Sulindac/Eflornithine Combination for ...
https://consultqd.clevelandclinic.org/phase-3-study-tests-sulindac-eflornithine-combination-for-familial-adenomatous-polyposis/
FAP is an inherited colorectal cancer (CRC) syndrome caused by a germline mutation in the adenomatous polyposis coli gene.
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https://consultqd.clevelandclinic.org/phase-3-study-tests-sulindac-eflornithine-combination-for-familial-adenomatous-polyposis/
FAP is an inherited colorectal cancer (CRC) syndrome caused by a germline mutation in the adenomatous polyposis coli gene.
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28
Carol A. Burke, MD, on Eflornithine+Sulindac for Treating ...
https://www.consultant360.com/podcast/consultant360/gastroenterology/carol-burke-md-eflornithinesulindac-treating-familial
Carol Burke: FAP is a systemic, serious hereditary colorectal cancer syndrome that results in hundreds to thousands of colon polyps, and in most cases, the ...
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https://www.consultant360.com/podcast/consultant360/gastroenterology/carol-burke-md-eflornithinesulindac-treating-familial
Carol Burke: FAP is a systemic, serious hereditary colorectal cancer syndrome that results in hundreds to thousands of colon polyps, and in most cases, the ...
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29
Docosahexaenoic acid sensitizes colon cancer cells to ...
https://www.spandidos-publications.com/10.3892/or.2012.1706
Sulindac analogs represent one of the most efficacious groups of NSAIDs reducing the risk of colon cancer. Recent studies have shown that ...
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https://www.spandidos-publications.com/10.3892/or.2012.1706
Sulindac analogs represent one of the most efficacious groups of NSAIDs reducing the risk of colon cancer. Recent studies have shown that ...
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30
Inhibition of rat colon tumors by sulindac and sulindac sulfone ...
https://journals.physiology.org/doi/full/10.1152/ajpgi.2000.278.2.G266
Chemoprevention of colorectal cancer by nonsteroidal anti-inflammatory drugs (NSAIDs) is arguably the most promising area for reducing the clinical problem. The ...
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https://journals.physiology.org/doi/full/10.1152/ajpgi.2000.278.2.G266
Chemoprevention of colorectal cancer by nonsteroidal anti-inflammatory drugs (NSAIDs) is arguably the most promising area for reducing the clinical problem. The ...
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31
Effects of α-lactalbumin and sulindac on primary ... - De Gruyter
https://www.degruyter.com/document/doi/10.1515/tjb-2017-0263/html
It was appeared that α-lactalbumin and sulindac may triggger mechanisms of apoptosis in both primary and metastatic colon carcinoma cell ...
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https://www.degruyter.com/document/doi/10.1515/tjb-2017-0263/html
It was appeared that α-lactalbumin and sulindac may triggger mechanisms of apoptosis in both primary and metastatic colon carcinoma cell ...
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32
NSAIDs and Colorectal Cancer Control: Promise ... - Springer
https://link.springer.com/article/10.1007/s40495-015-0042-x
They also observed that this effect of sulindac was similar in magnitude to that obtained after long-term administration of NSAIDs with polyp ...
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https://link.springer.com/article/10.1007/s40495-015-0042-x
They also observed that this effect of sulindac was similar in magnitude to that obtained after long-term administration of NSAIDs with polyp ...
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33
S0820, "A Double Blind Placebo-Controlled Trial of ...
https://cancer.uthscsa.edu/clinical-trials-and-research/clinical-trial/s0820-double-blind-placebo-controlled-trial
S0820, "A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers ...
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https://cancer.uthscsa.edu/clinical-trials-and-research/clinical-trial/s0820-double-blind-placebo-controlled-trial
S0820, "A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers ...
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34
A Double Blind Placebo-Controlled Trial of Eflornithine and ...
https://www.mdanderson.org/patients-family/diagnosis-treatment/clinical-trials/clinical-trials-index/clinical-trials-detail.IDSWOGS0820.html
A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in ...
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https://www.mdanderson.org/patients-family/diagnosis-treatment/clinical-trials/clinical-trials-index/clinical-trials-detail.IDSWOGS0820.html
A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in ...
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35
Sulindac activates NF-kappaB signaling in colon cancer cells
https://www.garvan.org.au/research/publications/11872
BACKGROUND: The non-steroidal anti-inflammatory drug (NSAID) sulindac has shown efficacy in preventing colorectal cancer.
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https://www.garvan.org.au/research/publications/11872
BACKGROUND: The non-steroidal anti-inflammatory drug (NSAID) sulindac has shown efficacy in preventing colorectal cancer.
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36
Sulindac plus erlotinib for familial adenomatous polyposis
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(16)30024-9/fulltext
The COX-2 inhibitor sulindac plus the EGFR inhibitor erlotinib might reduce the risk of duodenal polyps and subsequent cancer in patients ...
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https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(16)30024-9/fulltext
The COX-2 inhibitor sulindac plus the EGFR inhibitor erlotinib might reduce the risk of duodenal polyps and subsequent cancer in patients ...
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37
Oxazole and thiazole analogs of sulindac for cancer prevention
https://www.future-science.com/doi/10.4155/fmc-2017-0182
Sulindac, a widely used nonsteroidal anti-inflammatory drug, can prevent adenomatous colorectal polyps and colon cancer, especially in ...
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https://www.future-science.com/doi/10.4155/fmc-2017-0182
Sulindac, a widely used nonsteroidal anti-inflammatory drug, can prevent adenomatous colorectal polyps and colon cancer, especially in ...
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38
Clinical Trials Details - Stamford Health
https://www.stamfordhealth.org/care-treatment/cancer/clinical-trials/details/?id=13
Phase III, Double Blind Placebo-Controlled Trial of Eflornithine & Sulindac to Prevent Recurrence of High Risk Adenomas & Second Primary Colorectal Cancers in ...
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https://www.stamfordhealth.org/care-treatment/cancer/clinical-trials/details/?id=13
Phase III, Double Blind Placebo-Controlled Trial of Eflornithine & Sulindac to Prevent Recurrence of High Risk Adenomas & Second Primary Colorectal Cancers in ...
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39
Inhibitory Effects of 5-Fluorouracil and Oxaliplatin on Human ...
https://ar.iiarjournals.org/content/29/1/435
Conclusion: It was apparent that combination of 5-FU or oxaliplatin with sulindac sulfide results in a powerful inhibition of growth of colorectal carcinoma ...
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https://ar.iiarjournals.org/content/29/1/435
Conclusion: It was apparent that combination of 5-FU or oxaliplatin with sulindac sulfide results in a powerful inhibition of growth of colorectal carcinoma ...
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40
Sulindac Terminated Phase N/A Trials for Colorectal Cancer ...
https://go.drugbank.com/drugs/DB00605/clinical_trials?conditions=DBCOND0028391&purpose=prevention&status=terminated
NCT00003365, Sulindac and Plant Compounds in Preventing Colon Cancer. Quercetin (DB04216) · Sulindac (DB00605) ...
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https://go.drugbank.com/drugs/DB00605/clinical_trials?conditions=DBCOND0028391&purpose=prevention&status=terminated
NCT00003365, Sulindac and Plant Compounds in Preventing Colon Cancer. Quercetin (DB04216) · Sulindac (DB00605) ...
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41
Sulindac Treatment and Fas Deletion: Effects on a Colon ...
https://curate.nd.edu/show/qr46qz2370c
Gene expression analysis of the human colon cancer cell line, HT-29, demonstrated that MMP7 and HMGB1 were downregulated after sulindac ...
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https://curate.nd.edu/show/qr46qz2370c
Gene expression analysis of the human colon cancer cell line, HT-29, demonstrated that MMP7 and HMGB1 were downregulated after sulindac ...
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42
Colon tumor cell growth-inhibitory activity of sulindac sulfide ...
https://europepmc.org/article/pmc/pmc2955813
Here, we show that the NSAID sulindac sulfide (SS) inhibits cyclic guanosine 3',5'-monophosphate (cGMP) phosphodiesterase (PDE) activity in colon tumor cell ...
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https://europepmc.org/article/pmc/pmc2955813
Here, we show that the NSAID sulindac sulfide (SS) inhibits cyclic guanosine 3',5'-monophosphate (cGMP) phosphodiesterase (PDE) activity in colon tumor cell ...
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43
Sulindac | 49676 Citations | Top Authors | Related Topics
https://typeset.io/topics/sulindac-2y84128f
TL;DR: Sulindac reduces the number and size of colorectal adenomas in patients with familial adenomatous polyposis, but its effect is incomplete, and it is ...
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https://typeset.io/topics/sulindac-2y84128f
TL;DR: Sulindac reduces the number and size of colorectal adenomas in patients with familial adenomatous polyposis, but its effect is incomplete, and it is ...
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44
Sulindac activates NF-κB signaling in colon cancer cells
https://digital.library.adelaide.edu.au/dspace/handle/2440/111738
The non-steroidal anti-inflammatory drug (NSAID) sulindac has shown efficacy in preventing colorectal cancer. This potent anti-tumorigenic effect is mediated ...
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https://digital.library.adelaide.edu.au/dspace/handle/2440/111738
The non-steroidal anti-inflammatory drug (NSAID) sulindac has shown efficacy in preventing colorectal cancer. This potent anti-tumorigenic effect is mediated ...
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45
Eflornithine and/or Sulindac in Preventing Recurrence of High-Risk ...
https://www.gancorp.org/trials-providers/trials/colon-rectal-cancer/3280
Eflornithine and/or Sulindac in Preventing Recurrence of High-Risk Adenomas and Second Primary Disease in Patients with Stage 0-III Colon or Rectal Cancer.
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https://www.gancorp.org/trials-providers/trials/colon-rectal-cancer/3280
Eflornithine and/or Sulindac in Preventing Recurrence of High-Risk Adenomas and Second Primary Disease in Patients with Stage 0-III Colon or Rectal Cancer.
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46
Eflornithine and Sulindac in Preventing ... - HealthEngine
https://healthinfo.healthengine.com.au/eflornithine-and-sulindac-in-preventing-colorectal-cancer-in-patients-with-colon-polyps
Rationale: Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of eflornithine and ...
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https://healthinfo.healthengine.com.au/eflornithine-and-sulindac-in-preventing-colorectal-cancer-in-patients-with-colon-polyps
Rationale: Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of eflornithine and ...
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47
(PDF) Sulindac activates NF-κB signaling in colon cancer cells
https://www.researchgate.net/publication/257300015_Sulindac_activates_NF-kB_signaling_in_colon_cancer_cells
Background The non-steroidal anti-inflammatory drug (NSAID) sulindac has shown efficacy in preventing colorectal cancer.
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https://www.researchgate.net/publication/257300015_Sulindac_activates_NF-kB_signaling_in_colon_cancer_cells
Background The non-steroidal anti-inflammatory drug (NSAID) sulindac has shown efficacy in preventing colorectal cancer.
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48
A Double Blind Placebo-Controlled Trial of Eflornithine and ...
https://carle.org/For-Providers/Research/clinical-trials/15
("Second primary colorectal cancer" means a new colorectal cancer developing within the colorectum.) The study drugs eflornithine and sulindac are tablets which ...
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https://carle.org/For-Providers/Research/clinical-trials/15
("Second primary colorectal cancer" means a new colorectal cancer developing within the colorectum.) The study drugs eflornithine and sulindac are tablets which ...
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49
HIF1α deficiency reduces inflammation in a mouse model of ...
https://journals.biologists.com/Toolbox/DownloadCombinedArticleAndSupplmentPdf?resourceId=3759&multimediaId=1869301&pdfUrl=%2Fcob%2Fcontent_public%2Fjournal%2Fdmm%2F8%2F9%2F10.1242_dmm.019000%2F6%2Fdmm019000.pdf
We also analysed the effect of sulindac sulfide on the aryl hydrocarbon receptor (AHR) pathway in vitro in colon cancer cells. Most sulindac-treated mice ...
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https://journals.biologists.com/Toolbox/DownloadCombinedArticleAndSupplmentPdf?resourceId=3759&multimediaId=1869301&pdfUrl=%2Fcob%2Fcontent_public%2Fjournal%2Fdmm%2F8%2F9%2F10.1242_dmm.019000%2F6%2Fdmm019000.pdf
We also analysed the effect of sulindac sulfide on the aryl hydrocarbon receptor (AHR) pathway in vitro in colon cancer cells. Most sulindac-treated mice ...
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50
Sulindac | Sigma-Aldrich
https://www.sigmaaldrich.com/KZ/ru/search/sulindac?focus=papers&page=1&perpage=30&sort=relevance&term=sulindac&type=citation_search
Small chemical compound sulindac has been approved as a preventive approach against colon cancer for its effectiveness in treatment of ...
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https://www.sigmaaldrich.com/KZ/ru/search/sulindac?focus=papers&page=1&perpage=30&sort=relevance&term=sulindac&type=citation_search
Small chemical compound sulindac has been approved as a preventive approach against colon cancer for its effectiveness in treatment of ...
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51
Promising Drug Fails in Test Involving a Kind of Cancer
https://www.nytimes.com/2002/04/04/us/promising-drug-fails-in-test-involving-a-kind-of-cancer.html
In those patients, sulindac and anti-inflammatory drugs like it can hold off colon cancer for several years. In the normal course of familial ...
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https://www.nytimes.com/2002/04/04/us/promising-drug-fails-in-test-involving-a-kind-of-cancer.html
In those patients, sulindac and anti-inflammatory drugs like it can hold off colon cancer for several years. In the normal course of familial ...
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52
Cyclooxygenase-independent Induction of Apoptosis by ...
https://www.jbc.org/article/S0021-9258(20)75804-7/fulltext
Cyclooxygenase-independent Induction of Apoptosis by Sulindac Sulfone Is Mediated by Polyamines in Colon Cancer* · EXPERIMENTAL PROCEDURES.
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https://www.jbc.org/article/S0021-9258(20)75804-7/fulltext
Cyclooxygenase-independent Induction of Apoptosis by Sulindac Sulfone Is Mediated by Polyamines in Colon Cancer* · EXPERIMENTAL PROCEDURES.
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53
Sulindac activates NF-κB signaling in colon cancer cells
https://cyberleninka.org/article/n/656458
Background: The non-steroidal anti-inflammatory drug (NSAID) sulindac has shown efficacy in preventing colorectal cancer. This potent anti-tumorigenic effect is ...
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https://cyberleninka.org/article/n/656458
Background: The non-steroidal anti-inflammatory drug (NSAID) sulindac has shown efficacy in preventing colorectal cancer. This potent anti-tumorigenic effect is ...
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54
The Chemopreventive Agent Sulindac Attenuates Expression ...
https://jpet.aspetjournals.org/content/308/2/434
To test this hypothesis, we exposed HT-29 colon carcinoma cells to sulindac. Sulindac induced a sustained decrease in mRNA and protein ...
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https://jpet.aspetjournals.org/content/308/2/434
To test this hypothesis, we exposed HT-29 colon carcinoma cells to sulindac. Sulindac induced a sustained decrease in mRNA and protein ...
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55
Randomized phase II trial of sulindac, atorvastatin, and ...
https://mayoclinic.pure.elsevier.com/en/publications/randomized-phase-ii-trial-of-sulindac-atorvastatin-and-prebiotic-
Sulindac, atorvastatin, or prebiotic dietary fiber may reduce colorectal cancer (CRC) risk. However, clinical trial data are currently limited.
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https://mayoclinic.pure.elsevier.com/en/publications/randomized-phase-ii-trial-of-sulindac-atorvastatin-and-prebiotic-
Sulindac, atorvastatin, or prebiotic dietary fiber may reduce colorectal cancer (CRC) risk. However, clinical trial data are currently limited.
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56
Sulindac Modulates the Response of Proficient MMR ...
https://www.medschool.lsuhsc.edu/deanseminar/2020/09/02/sulindac-modulates-the-response-of-proficient-mmr-colorectal-cancer-to-anti-pd-l1-immunotherapy/
Understand the clinical challenges of treating colorectal cancer (CRC) · Understand the immunomodulatory role of sulindac in CRC · Understand the ...
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https://www.medschool.lsuhsc.edu/deanseminar/2020/09/02/sulindac-modulates-the-response-of-proficient-mmr-colorectal-cancer-to-anti-pd-l1-immunotherapy/
Understand the clinical challenges of treating colorectal cancer (CRC) · Understand the immunomodulatory role of sulindac in CRC · Understand the ...
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57
The NSAID sulindac is chemopreventive in the mouse distal ...
https://researchdirect.westernsydney.edu.au/islandora/object/uws:10863
The non-steroidal anti-inflammatory drug sulindac is an effective chemopreventive agent in sporadic colorectal cancer but its potential benefit in mismatch ...
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https://researchdirect.westernsydney.edu.au/islandora/object/uws:10863
The non-steroidal anti-inflammatory drug sulindac is an effective chemopreventive agent in sporadic colorectal cancer but its potential benefit in mismatch ...
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58
Colon Cancer Clinical Trial: Eflornithine and Sulindac in ...
https://www.survivornet.com/clinical-trials/colon-cancer/eflornithine-and-sulindac-in-preventing-colorectal-cancer-in-patients-with-colon-polyps/
Colon Cancer - A Phase III Randomized, Double-Blind, Placebo-Controlled Clinical Trial of the Combination of DFMO and Sulindac to Decrease the.
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https://www.survivornet.com/clinical-trials/colon-cancer/eflornithine-and-sulindac-in-preventing-colorectal-cancer-in-patients-with-colon-polyps/
Colon Cancer - A Phase III Randomized, Double-Blind, Placebo-Controlled Clinical Trial of the Combination of DFMO and Sulindac to Decrease the.
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59
The effects of Sulindac on cell viability, cell cycle and ...
https://dergipark.org.tr/tr/pub/entupdates/issue/58977/750434
Sulindac was found to slightly increase vascular endothelial growth factor receptor 2 (VEGF-R2) and decrease ADAMTS1 levels in pharyngeal cancer cells.
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https://dergipark.org.tr/tr/pub/entupdates/issue/58977/750434
Sulindac was found to slightly increase vascular endothelial growth factor receptor 2 (VEGF-R2) and decrease ADAMTS1 levels in pharyngeal cancer cells.
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60
SMAC-dependent apoptosis - JSTOR
https://www.jstor.org/stable/25748798
review July 18, 2010). Nonsteroidal anti-Inflammatory drugs (NSAIDs) such as sulindac effectively prevent colon cancer in humans and rodent models.
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https://www.jstor.org/stable/25748798
review July 18, 2010). Nonsteroidal anti-Inflammatory drugs (NSAIDs) such as sulindac effectively prevent colon cancer in humans and rodent models.
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61
A redox/polyamine dependent effect - DSpace Repository
https://ir.stonybrook.edu/xmlui/handle/11401/66397
Phospho-sulindac (OXT-922) inhibits the growth of human colon cancer cell lines: A redox/polyamine dependent effect ... Preservation Department, Stony Brook ...
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https://ir.stonybrook.edu/xmlui/handle/11401/66397
Phospho-sulindac (OXT-922) inhibits the growth of human colon cancer cell lines: A redox/polyamine dependent effect ... Preservation Department, Stony Brook ...
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62
Multistage vector delivery of Sulindac and Silymarin fo
https://www.scitechnol.com/proceedings/multistage-vector-delivery-of-sulindac-and-silymarin-for-prevention-of-colon-cancer-375.html
Preferential binding and internalization of these drugs into colon cancer cells was obtained using a targeting strategy against the protein meprin A, which is ...
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https://www.scitechnol.com/proceedings/multistage-vector-delivery-of-sulindac-and-silymarin-for-prevention-of-colon-cancer-375.html
Preferential binding and internalization of these drugs into colon cancer cells was obtained using a targeting strategy against the protein meprin A, which is ...
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63
Phospho-Sulindac (OXT-328), a Novel Sulindac Derivative, Is ...
https://dspace.sunyconnect.suny.edu/handle/1951/60519?show=full
Phospho-Sulindac (OXT-328), a Novel Sulindac Derivative, Is Safe and Effective in Colon Cancer Prevention in Mice ...
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https://dspace.sunyconnect.suny.edu/handle/1951/60519?show=full
Phospho-Sulindac (OXT-328), a Novel Sulindac Derivative, Is Safe and Effective in Colon Cancer Prevention in Mice ...
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64
Chemopreventive effects of NSAIDs against colorectal cancer
https://www.semanticscholar.org/paper/Chemopreventive-effects-of-NSAIDs-against-cancer%3A-Watson/8ede96c78e163b944d87ffc144646f49885badc3
Chemopreventive effects of NSAIDs against colorectal cancer: ... profile analysis of colon cancer cells in response to sulindac or aspirin.
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https://www.semanticscholar.org/paper/Chemopreventive-effects-of-NSAIDs-against-cancer%3A-Watson/8ede96c78e163b944d87ffc144646f49885badc3
Chemopreventive effects of NSAIDs against colorectal cancer: ... profile analysis of colon cancer cells in response to sulindac or aspirin.
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65
Sulindac (Oral Route) Precautions - Mayo Clinic
https://www.mayoclinic.org/drugs-supplements/sulindac-oral-route/precautions/drg-20069763
› drg-20069763
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https://www.mayoclinic.org/drugs-supplements/sulindac-oral-route/precautions/drg-20069763
› drg-20069763
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66
Drug Combo Targets Polyp Growth - Cancer Today
https://www.cancertodaymag.org/fall2018/drug-combo-targets-polyp-growth/
The findings from this study, published in the May 2018 JAMA Oncology, showed the drug combination also reduced the number of colorectal ...
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https://www.cancertodaymag.org/fall2018/drug-combo-targets-polyp-growth/
The findings from this study, published in the May 2018 JAMA Oncology, showed the drug combination also reduced the number of colorectal ...
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67
Conlon Cancer Prevention - Colorectal Cancer Prevention
https://www.youtube.com/watch?v=ptwJS1arZco
colorectal cancer is the fourth most common cancer in men and women. ... such as piroxicam, sulindac, and aspirin, may prevent adenoma ...
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https://www.youtube.com/watch?v=ptwJS1arZco
colorectal cancer is the fourth most common cancer in men and women. ... such as piroxicam, sulindac, and aspirin, may prevent adenoma ...
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68
mobile.Labmedica.com
https://mobile.labmedica.com/bioresearch/articles/294731515/a-novel-sulindac-derivative-safely-prevents-colon-cancer-in-mouse-model.html
› bioresearch › articles
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https://mobile.labmedica.com/bioresearch/articles/294731515/a-novel-sulindac-derivative-safely-prevents-colon-cancer-in-mouse-model.html
› bioresearch › articles
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69
Treatment trial testing for reduced recurrence of certain ...
https://www.mainlinehealth.org/research/clinical-trials/s0820
A double-blind, placebo-controlled trial of eflornithine and sulindac to prevent recurrence of high-risk adenomas and second primary colorectal cancers in ...
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https://www.mainlinehealth.org/research/clinical-trials/s0820
A double-blind, placebo-controlled trial of eflornithine and sulindac to prevent recurrence of high-risk adenomas and second primary colorectal cancers in ...
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70
Patients – Drugs & Side Effects
https://ruesch.georgetown.edu/reelspatients-drugs/
Capecitabine is used to treat colon or rectal cancer that has gotten worse or spread to other parts of the body. It is also used to prevent colon cancer from ...
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https://ruesch.georgetown.edu/reelspatients-drugs/
Capecitabine is used to treat colon or rectal cancer that has gotten worse or spread to other parts of the body. It is also used to prevent colon cancer from ...
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71
The Platelet-to-Lymphocyte Ratio Predicts Diabetic ...
https://www.dovepress.com/the-platelet-to-lymphocyte-ratio-predicts-diabetic-retinopathy-in-type-peer-reviewed-fulltext-article-DMSO
1Geriatric Diseases Institute of Chengdu/Cancer Prevention and Treatment ... severity in patients with inflammatory bowel disease (IBD), ...
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https://www.dovepress.com/the-platelet-to-lymphocyte-ratio-predicts-diabetic-retinopathy-in-type-peer-reviewed-fulltext-article-DMSO
1Geriatric Diseases Institute of Chengdu/Cancer Prevention and Treatment ... severity in patients with inflammatory bowel disease (IBD), ...
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72
Oral Chemotherapy for Previously-Treated Metastatic Colon ...
https://www.lonsurf.com/considering-lonsurf/oral-chemotherapy-for-colon-rectal-stomach-cancer
LONSURF is a prescription medicine used to treat people with colon, rectal, or stomach cancer that has spread to other parts of the body and who have been ...
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https://www.lonsurf.com/considering-lonsurf/oral-chemotherapy-for-colon-rectal-stomach-cancer
LONSURF is a prescription medicine used to treat people with colon, rectal, or stomach cancer that has spread to other parts of the body and who have been ...
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73
Eliquis and claritin - 1a-badsanierung.de
https://1a-badsanierung.de/eliquis-and-claritin.html
Cancer patients on certain oral chemotherapy drugs should be cautious about ... the laxatives taken before the procedure to clean the colon of fecal debris.
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https://1a-badsanierung.de/eliquis-and-claritin.html
Cancer patients on certain oral chemotherapy drugs should be cautious about ... the laxatives taken before the procedure to clean the colon of fecal debris.
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74
'Drug factory' implants eliminate ovarian, colorectal cancer in ...
https://news.rice.edu/news/2022/drug-factory-implants-eliminate-ovarian-colorectal-cancer-mice
HOUSTON – (March 2, 2022) – Rice University bioengineers have shown they can eradicate advanced-stage ovarian and colorectal cancer in mice ...
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https://news.rice.edu/news/2022/drug-factory-implants-eliminate-ovarian-colorectal-cancer-mice
HOUSTON – (March 2, 2022) – Rice University bioengineers have shown they can eradicate advanced-stage ovarian and colorectal cancer in mice ...
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75
LEAD FROM BEHIND Launch Reaches Millions
https://www.ccalliance.org/blog/prevention/lead-from-behind-launch-reaches-millions
... postoperative delirium, and a life-saving message — marked the launch of the LEAD FROM BEHIND colon cancer awareness initiative.
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https://www.ccalliance.org/blog/prevention/lead-from-behind-launch-reaches-millions
... postoperative delirium, and a life-saving message — marked the launch of the LEAD FROM BEHIND colon cancer awareness initiative.
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76
Why Not Use Oral S-1 in Colon Cancer? - Medscape
https://www.medscape.com/viewarticle/834019
Dr David Kerr reports that S-1, an oral fluoropyrimidine used as adjuvant therapy in stage III colon cancer, is noninferior to a 3-drug ...
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https://www.medscape.com/viewarticle/834019
Dr David Kerr reports that S-1, an oral fluoropyrimidine used as adjuvant therapy in stage III colon cancer, is noninferior to a 3-drug ...
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77
Rectal Cancer: Surgical Management, Basic and Clinical Research
https://books.google.com/books?id=fMTsCAAAQBAJ&pg=PA204&lpg=PA204&dq=sulindac+colon+cancer&source=bl&ots=8LlzFvM525&sig=ACfU3U1lxNJN4pAqfZhO0ZjGdCWECViTKA&hl=en&sa=X&ved=2ahUKEwjQhazCksL7AhUkEFkFHXzyAW8Q6AF6BQiiAhAD
This well-designed study is impressive evidence for the protective effects of aspirin against colorectal cancer. Sulindac on the other hand, unlike aspirin, ...
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https://books.google.com/books?id=fMTsCAAAQBAJ&pg=PA204&lpg=PA204&dq=sulindac+colon+cancer&source=bl&ots=8LlzFvM525&sig=ACfU3U1lxNJN4pAqfZhO0ZjGdCWECViTKA&hl=en&sa=X&ved=2ahUKEwjQhazCksL7AhUkEFkFHXzyAW8Q6AF6BQiiAhAD
This well-designed study is impressive evidence for the protective effects of aspirin against colorectal cancer. Sulindac on the other hand, unlike aspirin, ...
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78
Journal of the National Cancer Institute: JNCI
https://books.google.com/books?id=JTiookNSqXAC&pg=PA1610&lpg=PA1610&dq=sulindac+colon+cancer&source=bl&ots=PB48iI6lok&sig=ACfU3U1mgY7wz7CUqCkU9wvLKpVgfDbkVA&hl=en&sa=X&ved=2ahUKEwjQhazCksL7AhUkEFkFHXzyAW8Q6AF6BQijAhAD
Autochthonous colon tumors effectively suppressed by nonsteroidal anti ... Indomethacin Indomethacin or meclofenamate Sulindac Aspirin Piroxicam and DFMO ...
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https://books.google.com/books?id=JTiookNSqXAC&pg=PA1610&lpg=PA1610&dq=sulindac+colon+cancer&source=bl&ots=PB48iI6lok&sig=ACfU3U1mgY7wz7CUqCkU9wvLKpVgfDbkVA&hl=en&sa=X&ved=2ahUKEwjQhazCksL7AhUkEFkFHXzyAW8Q6AF6BQijAhAD
Autochthonous colon tumors effectively suppressed by nonsteroidal anti ... Indomethacin Indomethacin or meclofenamate Sulindac Aspirin Piroxicam and DFMO ...
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79
Trial of rectal cancer drug leads to remission in every patient
https://www.axios.com/2022/06/06/trial-rectal-cancer-drug-remission
Illustration: Sarah Grillo/Axios. A small cancer immunotherapy drug trial in patients with rectal cancer recently had an " ...
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https://www.axios.com/2022/06/06/trial-rectal-cancer-drug-remission
Illustration: Sarah Grillo/Axios. A small cancer immunotherapy drug trial in patients with rectal cancer recently had an " ...
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80
Colon Cancer Treatment - Vanderbilt-Ingram Cancer Center
https://www.vicc.org/cancer-info/adult-colon-cancer
Signs of colon cancer include blood in the stool or a change in bowel habits. Tests that examine the colon and rectum are used to diagnose colon ...
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https://www.vicc.org/cancer-info/adult-colon-cancer
Signs of colon cancer include blood in the stool or a change in bowel habits. Tests that examine the colon and rectum are used to diagnose colon ...
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81
Phytopharmaceuticals in Cancer Chemoprevention
https://books.google.com/books?id=0dPKBQAAQBAJ&pg=PA131&lpg=PA131&dq=sulindac+colon+cancer&source=bl&ots=Yq4sleM4DH&sig=ACfU3U1p6M9AEhylhwKcnenKIlDTceEtHA&hl=en&sa=X&ved=2ahUKEwjQhazCksL7AhUkEFkFHXzyAW8Q6AF6BQikAhAD
9.6 SULINDAC Giardiello et al.,39 in reviewing the role of sulindac with respect to ... a single patient developed Stage III cancer in the rectal stump.
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https://books.google.com/books?id=0dPKBQAAQBAJ&pg=PA131&lpg=PA131&dq=sulindac+colon+cancer&source=bl&ots=Yq4sleM4DH&sig=ACfU3U1p6M9AEhylhwKcnenKIlDTceEtHA&hl=en&sa=X&ved=2ahUKEwjQhazCksL7AhUkEFkFHXzyAW8Q6AF6BQikAhAD
9.6 SULINDAC Giardiello et al.,39 in reviewing the role of sulindac with respect to ... a single patient developed Stage III cancer in the rectal stump.
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