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1 Pathogenesis of paclitaxel-induced peripheral neuropathy
https://pubmed.ncbi.nlm.nih.gov/31758983/
Although highly effective in blocking tumor progression, paclitaxel also causes peripheral neuropathy as a side effect in 60-70% of chemotherapy patients.
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2 Risk factors for paclitaxel-induced peripheral neuropathy in ...
https://bmccancer.biomedcentral.com/articles/10.1186/s12885-018-4869-5
Paclitaxel induced peripheral neuropathy (PIPN), is the main dose-limiting and long lasting side effect of paclitaxel, with no fully understood ...
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3 Paclitaxel-induced peripheral neuropathy is caused ... - Nature
https://www.nature.com/articles/s41598-020-60990-8
Paclitaxel induces peripheral neuropathy as a side effect of cancer treatment. The underlying causes are unclear, but epidermal, ...
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4 Nerve Damage after Chemotherapy for Breast Cancer - NCI
https://www.cancer.gov/news-events/cancer-currents-blog/2017/peripheral-neuropathy-chemotherapy-breast-cancer
Many women who receive taxane-based chemotherapy to treat breast cancer experience long-term peripheral neuropathy, according to follow-up ...
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5 Cryotherapy May Help Prevent Neuropathy Caused by Taxol ...
https://www.breastcancer.org/research-news/cryotherapy-may-prevent-taxol-neuropathy
Cryotherapy May Help Prevent Neuropathy Caused by Taxol Chemotherapy ... A small study suggests that wearing frozen gloves and socks for 90 ...
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6 Answers to 8 FAQ About Chemotherapy-Induced Peripheral ...
https://www.mskcc.org/news/answers-faq-about-chemotherapy-induced-peripheral-neuropathy-cipn
1. How does chemotherapy sometimes cause peripheral neuropathy? ... Chemotherapy treatments cause peripheral neuropathy by damaging the nerves in ...
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7 Paclitaxel-induced peripheral neuropathy in early-stage ...
https://ascopubs.org/doi/abs/10.1200/JCO.2020.38.15_suppl.e12503
Background: Peripheral neuropathy is a major dose-limiting side effect of paclitaxel and can persist for up to two years after completing ...
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8 Cognitive Changes and Neuropathy from Chemotherapy ...
https://www.virginiacancer.com/cancer-survivorship/mental-health/cognitive-changes-and-neuropathy/
Chemo-induced neuropathy symptoms are usually the worst 3-5 months after the last chemotherapy dose. After that, symptoms may disappear completely, lessen, or ...
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9 Weekly Paclitaxel‐Induced Neurotoxicity in Breast Cancer ...
https://theoncologist.onlinelibrary.wiley.com/doi/10.1002/onco.13697
Neuropathy is a well-recognized toxicity of weekly paclitaxel treatment, with significant grade ≥ 2 CIPN reported in 27% of patients [2]. Our ...
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10 Tips for Managing Neuropathy - Dana-Farber Cancer Institute
https://www.dana-farber.org/health-library/articles/tips-for-managing-neuropathy/
Q: What are other risk factors for developing CIPN? A: Specific types of chemotherapy, radiation, and surgery can cause damage to nerves that can lead to ...
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11 Preventing Paclitaxel-Induced Peripheral Neuropathy
https://www.jpsmjournal.com/article/S0885-3924(06)00422-2/fulltext
Paclitaxel causes a dose-dependent, predominantly sensory distal axonopathy as a result of its capacity to bind to tubulin, block its polymerization, and ...
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12 Peripheral Neuropathy - American Cancer Society
https://www.cancer.org/treatment/treatments-and-side-effects/physical-side-effects/peripheral-neuropathy.html
Some chemotherapy drugs and other treatments for cancer can cause peripheral neuropathy, a set of symptoms caused by damage to nerves that control the ...
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13 Acupuncture for paclitaxel-induced peripheral neuropathy | JPR
https://www.dovepress.com/acupuncture-for-paclitaxel-induced-peripheral-neuropathy-a-review-of-c-peer-reviewed-fulltext-article-JPR
The underlying mechanism leading to the occurrence and development of PIPN. Paclitaxel causes damage to distal nerve fibers and lead to painful ...
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14 Chemotherapy-Induced Peripheral Neuropathy in Metastatic ...
https://www.ajmc.com/view/chemotherapy-induced-peripheral-neuropathy-in-metastatic-breast-cancer-patients-initiating-intravenous-paclitaxel-nab-paclitaxel
Chemotherapy-induced peripheral neuropathy (CIPN), which has been reported in >60% of patients with mBC treated with IV paclitaxel, is a common ...
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15 Numbness & Tingling - Peripheral neuropathy - Chemocare
https://chemocare.com/chemotherapy/side-effects/numbness-tingling.aspx
Certain chemotherapy drugs can cause peripheral neuropathy such as vinca alkaloids (vincristine), cisplatin, paclitaxel, and the podophyllotoxins (etoposide ...
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16 Neuropathy from chemo: Remedies and treatments
https://www.medicalnewstoday.com/articles/323481
Neuropathy is nerve damage that can cause tingling, numbness, and other sensations, often in the feet and hands. Neuropathy is a common side effect of ...
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17 Peripheral Neuropathy | Macmillan Cancer Support
https://www.macmillan.org.uk/cancer-information-and-support/impacts-of-cancer/peripheral-neuropathy
Some anti-cancer drugs can cause nerve damage. This is the most common cause of peripheral neuropathy in people with cancer. Cancer can cause peripheral ...
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18 Prevention and treatment of chemotherapy-induced peripheral ...
https://www.uptodate.com/contents/prevention-and-treatment-of-chemotherapy-induced-peripheral-neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse effect of ... Effect of cryotherapy on dose of adjuvant paclitaxel in ...
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19 Paclitaxel-induced painful neuropathy is associated with cha...
https://journals.lww.com/pain/fulltext/2017/08000/paclitaxel_induced_painful_neuropathy_is.14.aspx
Duggett, Natalie A.; Griffiths, Lisa A.; Flatters, Sarah J.L. ... Painful neuropathy is the major dose-limiting side effect of paclitaxel chemotherapy.
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20 Pathomechanisms of Paclitaxel-Induced Peripheral Neuropathy
https://mdpi-res.com/d_attachment/toxics/toxics-09-00229/article_deploy/toxics-09-00229-v2.pdf?version=1632466808
Paclitaxel is a potent antineoplastic agent that in tumor cells induces cell death via microtubule stabilization. However, it can cause ...
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21 Impact of Cold Therapy on Paclitaxel-Induced Peripheral ...
https://www.ons.org/cjon/26/1/impact-cold-therapy-paclitaxel-induced-peripheral-neuropathy-and-quality-life-patients
Taxane drugs, specifically paclitaxel, are known for causing a high rate of peripheral neuropathy (PN) (Chan et al., 2019; Peyton & Fischer-Cartlidge, 2019).
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22 Hemoglobin, Body Mass Index, and Age as Risk Factors for ...
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2776440
Increased risk for developing neuropathy in older patients has been identified in large-scale studies of oxaliplatin-treated and paclitaxel- ...
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23 Nerve changes and cancer drugs - Cancer Research UK
https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/cancer-drugs/side-effects/nerve-changes
If your symptoms do get worse, your doctor might suggest a different cancer treatment. Peripheral neuropathy caused by chemotherapy and targeted ...
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24 Reduction of Paclitaxel-induced Peripheral Neuropathy with ...
https://aacrjournals.org/clincancerres/article-pdf/7/5/1192/2078998/df050101192.pdf
dard-dose paclitaxel in breast cancer and other tumors for which peripheral neuropathy is the dose-limiting toxicity. INTRODUCTION. Peripheral neuropathy is ...
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25 Pathophysiology of Chemotherapy-Induced Peripheral ...
https://www.frontiersin.org/articles/10.3389/fnmol.2017.00174/full
Chemotherapy-induced neuropathy is a common, dose-dependent adverse effect of several antineoplastics. It can lead to detrimental dose ...
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26 Nilotinib in Preventing Paclitaxel-Induced Peripheral ...
https://clinicaltrials.gov/ct2/show/NCT04205903
Sometimes, this treatment can cause numbness and tingling, especially in the hands and feet. This is called chemotherapy-induced peripheral neuropathy. This ...
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27 Breast Cancer, Chemotherapy, and Peripheral Neuropathy
https://www.healthcentral.com/article/taxol-toes-coping-with-peripheral-neuropathy
Taxanes such as cabazitaxel, docetaxel, and paclitaxel. Some chemo meds can cause CIPN by negatively impacting the function of neurons (the ...
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28 Integrins protect sensory neurons in models of paclitaxel ...
https://www.pnas.org/doi/10.1073/pnas.2006050118
Paclitaxel is a common chemotherapeutic agent and often causes a form of sensory dysfunction termed chemotherapy-induced peripheral ...
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29 Neuropathy from Chemo: Remedies, Duration, and More
https://www.healthline.com/health/cancer/neuropathy-from-chemo
Peripheral neuropathy is a blanket term for pain and discomfort and other symptoms ... lenalidomide (Revlimid); oxaliplatin (Eloxatin); paclitaxel (Taxol) ...
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30 Discovery of Potential Neuroprotective Agents against ...
https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c01912
Chemotherapy-induced neurotoxicity is a common adverse effect of cancer ... (4) Paclitaxel-induced peripheral neuropathy (PIPN) is in ...
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31 Does carboplatin cause neuropathy? - Drugs.com
https://www.drugs.com/medical-answers/carboplatin-neuropathy-3562411/
Peripheral neuropathy due to cancer treatments (chemotherapy) can cause symptoms of pain, weakness, and numbness from nerve damage, usually in ...
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32 Nerve Problems or Neuropathy | Cancer.Net
https://www.cancer.net/coping-with-cancer/physical-emotional-and-social-effects-cancer/managing-physical-side-effects/nerve-problems-or-neuropathy
These include: Where the tumor is. A tumor might press on or grow into a nerve. This could cause nerve damage. Some chemotherapy drugs. Some chemotherapy ...
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33 Incidence of Neuropathy with Weekly Paclitaxel and Role of ...
https://www.thieme-connect.com/products/ejournals/pdf/10.4103/ijmpo.ijmpo_38_17.pdf
All patients with DM developed Grade 1 neuropathy, suggesting that weekly paclitaxel does not cause more severe neuropathy in patients with DM.
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34 What are the best remedies for neuropathy from chemo?
https://berkeley-institute.com/best-remedies-for-neuropathy-from-chemo/
Neuropathy is nerve damage that can cause tingling, numbness, and other sensations, often in the feet and hands. Neuropathy is a common side ...
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35 Chemo Induced Peripheral Neuropathy
https://www.hopkinsmedicine.org/neurology_neurosurgery/centers_clinics/peripheral_nerve/conditions/chemo_induced_peripheral_neuropathy.html
Chemotherapy can cause degeneration of peripheral sensory and motor nerves and cause patients to present with sensory disturbances, balance problems or weakness ...
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36 Neuro-immune interactions in paclitaxel-induced peripheral ...
https://www.tandfonline.com/doi/full/10.1080/0284186X.2021.1954241
These symptoms vary in intensity, but severity increases with escalating total doses of paclitaxel [8 ...
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37 Dealing With Peripheral Neuropathy After Breast Cancer ...
https://www.webmd.com/breast-cancer/breast-cancer-treatment-peripheral-neuropathy
How Does Taxane-Based Chemotherapy Cause Peripheral Neuropathy? · Albumin paclitaxel (Abraxane) · Docetaxel (Taxotere) · Paclitaxel (Taxol).
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38 Chemotherapy-Induced Peripheral Neuropathy - an overview
https://www.sciencedirect.com/topics/medicine-and-dentistry/chemotherapy-induced-peripheral-neuropathy
Neurotoxic chemotherapeutic agents may cause structural damage to peripheral nerves, resulting in aberrant somatosensory processing of the peripheral and/or ...
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39 Chemotherapy-evoked Painful Peripheral Neuropathy
https://academic.oup.com/painmedicine/article/2/1/8/1927042
Paclitaxel's neurotoxic effect has also generally been assumed to be due to its binding to beta-tubulin, which is the primary component of the ...
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40 A New Way to Prevent Nerve Damage Caused by ...
https://www.cuimc.columbia.edu/news/new-way-prevent-nerve-damage-caused-chemotherapy
› news › new-way-pre...
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41 Neuropathic Pain in Taxane-Induced Peripheral Neuropathy
https://journals.sagepub.com/doi/full/10.1177/1545968319860486
A retrospective study found that 10% of patients on docetaxel or paclitaxel had a dose reduction or treatment delay during treatment because of ...
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42 Chemotherapy-Induced Peripheral Neuropathy Cannot Be ...
https://www.curetoday.com/view/chemotherapy-induced-peripheral-neuropathy-cannot-be-cured-but-there-are-many-ways-patients-can-reduce-its-severity
Certain chemotherapy drugs, such as paclitaxel or docetaxel, can cause numbness and tingling in patients' hands and/or feet — a condition called ...
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43 Peripheral Neuropathy & Chemotherapy
https://www.mdanderson.org/patients-family/diagnosis-treatment/emotional-physical-effects/peripheral-neuropathy.html
How long do peripheral neuropathy symptoms last? Every case is different. Because neuropathy is caused by nerve damage, it depends largely on how well your ...
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44 Overview of neuropathy associated with taxanes for the ...
https://link.springer.com/article/10.1007/s00280-014-2607-5
Neuropathy is a common, dose-limiting side effect of taxane therapy that is often managed by dose reductions and delays. The severity, time to ...
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45 Peripheral Neuropathy - Abraxane
https://www.abraxanepro.com/metastatic-pancreatic-cancer/peripheral-neuropathy/
Learn about the incidence of peripheral neuropathy with 1st-line ABRAXANE + gemcitabine for metastatic pancreatic cancer. See safety & box warning on ...
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46 Preventing paclitaxel- induced peripheral neuropathy?
https://www.pharmacytoday.org/article/S1042-0991(15)31635-2/pdf
Peripheral neuropathy is an adverse effect caused by many cancer ... Glutamine is a nonessential amino ... treated with high-dose paclitaxel chemotherapy.
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47 5 Ways you Can Prevent Neuropathy From Chemo
https://gsmedicalcenter.org/5-ways-you-can-prevent-neuropathy-from-chemo/
Depending on the chemo drug, people can develop neuropathy immediately after receiving their first dose up to years after they have stopped ...
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48 Understanding Peripheral Neuropathy - Cancer Council
https://www.cancer.org.au/assets/pdf/understanding-peripheral-neuropathy
taxanes (e.g. docetaxel, paclitaxel), platinum ... Peripheral neuropathy is a complex condition that can cause many different symptoms. This is because the.
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49 Improving Chemotherapy-Induced Peripheral Neuropathy in ...
https://www.karger.com/Article/FullText/519000
Introduction: Chemotherapy-induced peripheral neuropathy (CIPN) is a common side ... and motor neuropathyChemotherapyOxaliplatinPaclitaxelFood supplement ...
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50 Mayo Clinic Q and A: Autonomic neuropathy after chemotherapy
https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-autonomic-neuropathy-after-chemotherapy-is-it-permanent/
While some chemotherapy drugs may cause neuropathy, others do not. Even with the drugs known potentially to be toxic to nerves, ...
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51 Vincristine-induced peripheral neuropathy is driven by ...
https://rupress.org/jem/article/218/5/e20201452/211846/Vincristine-induced-peripheral-neuropathy-is
The main side effect of vincristine is a peripheral neuropathy ... chemotherapeutic paclitaxel, which does not cause IL-1β release in ...
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52 Chemotherapy-Induced Peripheral Neuropathy - Buffalo, NY
https://www.roswellpark.org/cancertalk/202001/chemotherapy-induced-peripheral-neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a specific type of PN. It's caused when chemotherapy drugs cause harm to nerve cells by ...
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53 Paclitaxel and long-lasting sensory neuropathy
https://neuropathie.nu/paclitaxel-sensory-neuropathy/
Paclitaxel is known for inducing painful Chemotherapy-induced peripheral neuropathy (CIPN). Immune processes and neuro inflammation are linked to its path.
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54 Peripheral neuropathy and breast cancer
https://breastcancernow.org/information-support/facing-breast-cancer/going-through-treatment-breast-cancer/side-effects/side-effects-chemotherapy/peripheral-neuropathy
The most common chemotherapy drugs that cause peripheral neuropathy are: Paclitaxel · Docetaxel · Carboplatin · Eribulin · Vinorelbine. Other cancer treatments ...
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55 Chemotherapy – Induced Peripheral Neuropathy (CIPN)
http://www.bccancer.bc.ca/nursing-site/Documents/15.%20Peripheral%20Neuropathy.pdf
Do your symptoms affect your ability to sleep (insomnia)?. Value. •. What do you believe is causing this problem? •.
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56 CXCR1/2 pathways in paclitaxel-induced neuropathic pain
https://www.oncotarget.com/article/15533/text/
Chemotherapy-induced peripheral neuropathy (CIPN) is a type of neuropathic pain that represents a frequent and serious consequence of ...
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57 Treating Nerve Pain After Chemotherapy: An Option That Works
https://healthblog.uofmhealth.org/cancer-care/treating-nerve-pain-after-chemotherapy-an-option-works
Learn about treating nerve pain caused by chemotherapy, ... percent of breast cancer patients, peripheral neuropathy is a painful sensation.
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58 Managing Neuropathy After Chemotherapy in Patients With ...
https://www.archives-pmr.org/article/S0003-9993(16)30907-8/fulltext
This is a guide to help you understand neuropathy caused by chemotherapy, including what symptoms you ... Taxanes, such as taxol, paclitaxel, and docetaxel.
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59 Dog food additive could ease painful chemo side effect, JHU ...
https://hub.jhu.edu/2013/10/04/taxol-nerve-damage/
Four out of five cancer patients taking the chemotherapy drug Taxol suffer from peripheral neuropathy, painful nerve damage in their hands ...
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60 Peripheral Neuropathy (Nerve Damage) - Oncolink
https://www.oncolink.org/support/side-effects/neurological-side-effects/peripheral-neuropathy-nerve-damage/peripheral-neuropathy-nerve-damage
Peripheral neuropathy is a condition in which a nerve or group of nerves ... can cause neuropathy include: vincristine, vinblastine, vinorelbine, Taxol, ...
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61 Clinical and preclinical perspectives on Chemotherapy ...
https://www.bjanaesthesia.org/article/S0007-0912(17)53816-7/pdf
cause both acute and chronic peripheral neuropathy - chemo- ... doses of paclitaxel (<10mg/kg cumulative dose) did not markedly.
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62 Pharmacological augmentation of nicotinamide ... - eLife
https://elifesciences.org/articles/29626
The microtubule stabilizer, paclitaxel (PTX), is widely used for the ... Chemotherapy-induced peripheral neuropathy (CIPN) is the most ...
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63 On Being a Cancer Survivor:Patient Experience of Peripheral ...
https://medivizor.com/blog/2014/05/21/cancer-survivor-patient-experience-peripheral-neuropathy/
Chemotherapy induced peripheral neuropathy is a side effect of chemotherapy. Neuropathy is nerve damage and one cancer patient describes her ...
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64 Coping with Chemotherapy-Induced Peripheral Neuropathy
https://conquer-magazine.com/issues/2016/vol-2-no-5-october-2016-2/100-coping-with-chemotherapy-induced-peripheral-neuropathy
Drugs Causing Neuropathy. The most often used chemotherapy drugs that can cause neuropathy are: Taxanes: Taxol (paclitaxel), Taxotere ...
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65 Involvement of Substance P in Peripheral Neuropathy Induced ...
https://jpet.aspetjournals.org/content/jpet/337/1/226.full.pdf
Oxaliplatin, by contrast, did not increase the release of substance. P. These results suggest that substance P is involved in paclitaxel- induced neuropathy, ...
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66 Low Levels of NDRG1 in Nerve Tissue Are Predictive ... - PLOS
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164319
Sensory peripheral neuropathy caused by paclitaxel is a common and dose limiting toxicity, for which there are currently no validated ...
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67 Pathogenesis of paclitaxel-induced peripheral neuropathy
https://scholarworks.iupui.edu/bitstream/handle/1805/21963/Staff_2019_pathogenesis.pdf?sequence=1&isAllowed=y
While paclitaxel treatment does not directly lead to damage of mitochondrial DNA in neurons (Boyette-Davis et al., 2018), swollen and vacuolated mitochondria in ...
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68 Key Questions About Peripheral Neuropathy
https://www.cancercouncil.com.au/cancer-information/managing-cancer-side-effects/peripheral-neuropathy/key-questions-about-peripheral-neuropathy/
What causes this nerve damage? · certain chemotherapy drugs, particularly taxanes (e.g. docetaxel, paclitaxel), platinum drugs (e.g. carboplatin, cisplatin, ...
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69 Chemotherapy-Induced Peripheral ... - Cancer Network
https://www.cancernetwork.com/view/chemotherapy-induced-peripheral-neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a common treatment-related side effect of several widely used drugs.
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70 Meteorin alleviates Paclitaxel-induced peripheral neuropathy ...
https://www.biorxiv.org/content/10.1101/2022.09.13.507857v1.full
Chemotherapy-induced peripheral neuropathy (CIPN) arises due to neurotoxicity produced by chemotherapy drugs such as paclitaxel and oxaliplatin.
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71 Dimethyl Fumarate Ameliorates Paclitaxel-Induced ... - Cureus
https://www.cureus.com/articles/113332-dimethyl-fumarate-ameliorates-paclitaxel-induced-neuropathic-pain-in-rats
Paclitaxel (PTX)-induced peripheral neuropathy (PIPN) is nonresponsive to the currently available analgesics. Previous studies have shown ...
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72 Chemotherapy-induced peripheral neuropathy - Wikipedia
https://en.wikipedia.org/wiki/Chemotherapy-induced_peripheral_neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a nerve-damaging side effect of antineoplastic agents in the common cancer treatment, chemotherapy.
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73 Topical Cryotherapy in Reducing Pain in Patients With ...
https://www.mayo.edu/research/clinical-trials/cls-20198328
Peripheral neuropathy is a nerve problem that causes pain, numbness, tingling, swelling, or muscle weakness in different parts of the body. Paclitaxel ...
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74 Delayed Recovery and Increased Severity of Paclitaxel ...
https://jnccn.org/view/journals/jnccn/13/4/article-p417.xml
Paclitaxel-induced peripheral neuropathy (PIPN) usually begins with paresthesia and numbness. ... The neurotoxicity is cumulative and may result ...
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75 Management of Chemotherapy-Induced Peripheral Neuropathy
https://www.uspharmacist.com/article/management-of-chemotherapyinduced-peripheral-neuropathy
ABSTRACT: Peripheral neuropathy is a serious condition characterized by symmetrical, distal damage to the peripheral nerves that may be caused ...
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76 A model of toxic neuropathy in Drosophila reveals a role for ...
https://digitalcommons.wustl.edu/cgi/viewcontent.cgi?article=9956&context=open_access_pubs
agents such as vincristine and paclitaxel (taxol) causes a dose- limiting peripheral neuropathy, such that very aggressive cancers.
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77 Chemotherapy-Induced Peripheral Neuropathy
https://neuropathycommons.org/neuropathy/causes-neuropathy/chemotherapy-induced-peripheral-neuropathy
Causes of CIPN · Platinum-based (cisplatin, oxaliplatin) · Vinca alkaloids (vincristine, vinorelbine, vinblastine) · Taxanes (paclitaxel, docetaxel) · Eribulin ...
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78 paclitaxel-induced peripheral neuropathy - Science.gov
https://www.science.gov/topicpages/p/paclitaxel-induced+peripheral+neuropathy
Peripheral neuropathy is a major dose-limiting side effect of paclitaxel and cisplatin chemotherapy. In the current study, we tested the involvement of a ...
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79 Cold Mittens and Socks for Prevention of Chemotherapy ...
http://oregononcologyspecialists.com/wp-content/uploads/2019/06/CoolingMittsSocks_v02.pdf
Peripheral neuropathy is a set of symptoms caused by damage to the nerves that are distant from the ... such as taxane based chemotherapy (i.e. paclitaxel.
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80 1743-Anti-cancer drug induced peripheral neuropathy - eviQ
https://www.eviq.org.au/clinical-resources/side-effect-and-toxicity-management/neurological-and-sensory/1743-anti-cancer-drug-induced-peripheral-neuropath
Peripheral neuropathy is a common complication of several classes of chemotherapy agents. Chemotherapy agents cause an inflammation, injury or degeneration of ...
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81 Platinum and Taxane Induced Common Peroneal Nerve Palsy ...
http://www.anncaserep.com/open-access/platinum-and-taxane-induced-common-peroneal-nerve-palsy-foot-drop-case-series-and-review-of-the-literature-4502.pdf
The taxanes also cause neuropathy clinically similar to cisplatin induced neuropathic symptoms. Paclitaxel is more neurotoxic and causes CIPN in ...
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82 6848.full.pdf - Journal of Neuroscience
https://www.jneurosci.org/content/jneuro/39/35/6848.full.pdf
paclitaxel-induced mechanical allodynia in female nude mice (T-cell ... Chemotherapy-induced peripheral neuropathy (CIPN) is a major side ...
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83 Dietary Supplements in Chemotherapy-Induced Peripheral ...
https://encyclopedia.pub/entry/20942
Although ALC was somewhat capable of attenuating established mechanical hypersensitivity caused by paclitaxel and cisplatin, its efficacy as a treatment option ...
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84 Chemotherapy-induced peripheral neuropathic pain
https://www.bjaed.org/article/S2058-5349(17)30077-X/pdf
It can also cause an acute encephalopathy that can lead to coma and death. Docetaxel is a semi-synthetic analogue of paclitaxel and shows.
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85 Usefulness of Duloxetine for Paclitaxel-Induced Peripheral ...
https://ar.iiarjournals.org/content/35/1/359
However, as a trade-off, reportedly as often as 57% to 83% of the time, these agents cause painful chemotherapy-induced peripheral neuropathy (CIPN), is a ...
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86 What you need to know as a patient or provider - YouTube
https://www.youtube.com/watch?v=rLH0ZcKn7iU
UVMLarnerMed
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87 Early Study Suggests Potential Role of Paclitaxel in Peripheral ...
https://ascopost.com/News/58192
In discovering how certain chemotherapy drugs cause peripheral neuropathy, researchers at Dana-Farber Cancer Institute have found a ...
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88 ONS 2018: Peripheral Neuropathy Is More Severe With ...
https://www.practiceupdate.com/content/ons-2018-peripheral-neuropathy-is-more-severe-with-paclitaxel-than-with-docetaxel-in-patients-with-breast-cancer/67597
Tofthagen C, McAllister RD, Visovsky C. Peripheral neuropathy caused by Paclitaxel and docetaxel: an evaluation and comparison of symptoms. J ...
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89 Nerve damage | Canadian Cancer Society
https://cancer.ca/en/treatments/side-effects/nerve-damage
Certain types of chemotherapy, radiation therapy and surgery can also cause nervous system problems. Cancer. Brain and spinal cord tumours can cause nervous ...
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90 The Vitamin E Preventive Effect on Taxol-Induced Neuropathy ...
https://brieflands.com/articles/jjnpp-65027.html
One of the most important drugs used in breast cancer chemotherapy regimens, Taxol is considered as the most common cause of neuropathy in such cases. The aim ...
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91 When Cancer Treatment Packs a Painful Punch
https://www.painresearchforum.org/news/41532-painful-chemotherapy-induced-neuropathy-tk
... on a rat model of paclitaxel-induced peripheral neuropathy. ... “So we got desperate, and we did quantitative electron microscopy of the ...
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92 Cancer and Peripheral Nerve Disease - BINASSS
https://www.binasss.sa.cr/mayo2021/24.pdf
Chemotherapy-induced PN is the most common type of neuropathy seen in patients ... Cancer-related neuropathy may be caused by direct tumor invasion or ...
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93 Bilateral facial nerve palsy secondary to the administration of ...
https://www.annalsofoncology.org/article/S0923-7534(19)57389-6/pdf
Neuropathy, predominantly sensory, but also motor and autonomic, is a well-described toxicity of standard-dose paclitaxel. [5, 6]. The sensory neuropathy ...
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94 Mitigating Taxol-Induced Neuropathy through Modulation of ...
https://grantome.com/grant/NIH/R43-CA199928-02
Despite its well-documented anti-cancer properties, taxol is known to cause chemotherapy-induced peripheral neuropathy (CIPN). CIPN affects approximately 30% - ...
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95 Role of Complement in a Rat Model of Paclitaxel-Induced ...
https://www.jimmunol.org/content/200/12/4094
Chemotherapy-induced peripheral neuropathy (CIPN) is a painful and debilitating side effect of cancer chemotherapy with an unclear ...
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96 Paclitaxel-induced neuropathic pain - Elsevier
https://www.elsevier.es/en-revista-porto-biomedical-journal-445-articulo-paclitaxel-induced-neuropathic-pain-unravelling-underlying-S2444866417301721
Chemotherapy-induced neuropathy (CIN) is one of the most common side effects. The mechanisms underlying CIN are starting to be uncovered namely the alterations ...
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97 Chemotherapy-Induced Peripheral Neuropathy
https://copingmag.com/chemotherapy-induced-peripheral-neuropathy/
For long-lasting, painful CIPN, duloxetine (Cymbalta) may help to alleviate your symptoms, especially if your CIPN is caused by paclitaxel or ...
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98 Clinical and preclinical perspectives on Chemotherapy ...
https://www.bjanaesthesia.org.uk/article/S0007-0912(17)53816-7/abstract
Initial work investigating the neurotoxicity associated with paclitaxel involved direct application of paclitaxel to peripheral nerves, resulting in ...
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