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Google Keyword Rankings for : bmi 1 colon cancer
1
Bmi-1 promotes the invasion and migration of colon cancer ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029956/
The oncogene, Bmi-1, promotes the development of hematologic malignancies and many solid tumors. The aim of the present study was to elucidate ...
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029956/
The oncogene, Bmi-1, promotes the development of hematologic malignancies and many solid tumors. The aim of the present study was to elucidate ...
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2
A novel BMI-1 inhibitor QW24 for the treatment of stem-like ...
https://jeccr.biomedcentral.com/articles/10.1186/s13046-019-1392-8
BMI-1, a critical regulator of self-renewal in the maintenance of CICs, is identified as a potential target for colorectal cancer therapy.
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https://jeccr.biomedcentral.com/articles/10.1186/s13046-019-1392-8
BMI-1, a critical regulator of self-renewal in the maintenance of CICs, is identified as a potential target for colorectal cancer therapy.
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3
Lower Bmi-1 Expression May Predict Longer Survival of Colon ...
https://www.karger.com/Article/Fulltext/452510
Bmi-1 is a member of the polycomb group which functions as a transcriptional repressor [3,4]. Bmi-1 gene is associated with tumor invasion and ...
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https://www.karger.com/Article/Fulltext/452510
Bmi-1 is a member of the polycomb group which functions as a transcriptional repressor [3,4]. Bmi-1 gene is associated with tumor invasion and ...
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4
BMI1 Is a Therapeutic Target in Colorectal Cancer
https://aacrjournals.org/cancerdiscovery/article/4/2/OF9/4295/BMI1-Is-a-Therapeutic-Target-in-Colorectal
Major finding: BMI1 inhibition irreversibly impairs the self-renewal of colorectal cancer–initiating cells. · Clinical relevance: A small-molecule BMI1 inhibitor ...
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https://aacrjournals.org/cancerdiscovery/article/4/2/OF9/4295/BMI1-Is-a-Therapeutic-Target-in-Colorectal
Major finding: BMI1 inhibition irreversibly impairs the self-renewal of colorectal cancer–initiating cells. · Clinical relevance: A small-molecule BMI1 inhibitor ...
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5
Body Mass Index and Long-Term Outcomes in Patients With ...
https://www.frontiersin.org/articles/10.3389/fonc.2018.00620/full
Conclusions: BMI is an important consideration in patients with colorectal cancer. Outcomes are stage-dependent where in some situations obesity ...
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https://www.frontiersin.org/articles/10.3389/fonc.2018.00620/full
Conclusions: BMI is an important consideration in patients with colorectal cancer. Outcomes are stage-dependent where in some situations obesity ...
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6
Association of Obesity With Risk of Early-Onset Colorectal ...
https://jamanetwork.com/journals/jamaoncology/fullarticle/2705608
A recent meta-analysis found a higher risk of colon cancer for each 5-unit increment in BMI of 30% among men and 12% among women. This analysis ...
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https://jamanetwork.com/journals/jamaoncology/fullarticle/2705608
A recent meta-analysis found a higher risk of colon cancer for each 5-unit increment in BMI of 30% among men and 12% among women. This analysis ...
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7
Targeting BMI-1-mediated epithelial–mesenchymal transition ...
https://www.sciencedirect.com/science/article/pii/S2211383520308170
3.1. BMI-1 is overexpressed in liver metastases of human colorectal cancer. We analyzed the BMI-1 expression level in a cohort of 41 normal subjects ...
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https://www.sciencedirect.com/science/article/pii/S2211383520308170
3.1. BMI-1 is overexpressed in liver metastases of human colorectal cancer. We analyzed the BMI-1 expression level in a cohort of 41 normal subjects ...
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8
Intestinal cancer stem cells marked by Bmi1 or Lgr5 ... - Nature
https://www.nature.com/articles/srep41838
Polycomb complex protein (Bmi1) and leucine-rich-repeat containing G-protein-coupled receptor 5 (Lgr5) have been identified as molecular markers ...
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https://www.nature.com/articles/srep41838
Polycomb complex protein (Bmi1) and leucine-rich-repeat containing G-protein-coupled receptor 5 (Lgr5) have been identified as molecular markers ...
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9
BMI1 Roles in Cancer Stem Cells and Its Association with ...
https://brieflands.com/articles/ijcm-82926.html
BMI1 is a colon stem cell marker that is up-regulated in colon CSCs and can be taken as a promising target for CRC therapy. This review describes the role of ...
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https://brieflands.com/articles/ijcm-82926.html
BMI1 is a colon stem cell marker that is up-regulated in colon CSCs and can be taken as a promising target for CRC therapy. This review describes the role of ...
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10
Roles of BMI1 in the Initiation, Progression, and Treatment of ...
https://journals.sagepub.com/doi/full/10.1177/15330338211070689
Hepatocellular carcinoma (HCC) accounts for 90% of all primary liver cancer cases. B-lymphoma Mo-MLV insertion region 1 (BMI1) has been identified as a proto- ...
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https://journals.sagepub.com/doi/full/10.1177/15330338211070689
Hepatocellular carcinoma (HCC) accounts for 90% of all primary liver cancer cases. B-lymphoma Mo-MLV insertion region 1 (BMI1) has been identified as a proto- ...
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11
Associations of Body Mass Index at Different Ages With Early ...
https://www.gastrojournal.org/article/S0016-5085(21)04074-9/fulltext
Incidence of colorectal cancer (CRC) in younger adults is increasing in ... Figure 1Flowchart showing selection of the study population.
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https://www.gastrojournal.org/article/S0016-5085(21)04074-9/fulltext
Incidence of colorectal cancer (CRC) in younger adults is increasing in ... Figure 1Flowchart showing selection of the study population.
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12
Bmi1 – A Path to Targeting Cancer Stem Cells
https://touchoncology.com/wp-content/uploads/sites/2/2017/12/private_articles_22792_pdf_EU-OncHem-13.2_147-51.pdf
The post-translational targeting of Bmi1 in colorectal carcinoma, lung adenocarcinoma, multiple myeloma and medulloblastoma have led to significant ...
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https://touchoncology.com/wp-content/uploads/sites/2/2017/12/private_articles_22792_pdf_EU-OncHem-13.2_147-51.pdf
The post-translational targeting of Bmi1 in colorectal carcinoma, lung adenocarcinoma, multiple myeloma and medulloblastoma have led to significant ...
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13
Early-life obesity and adulthood colorectal cancer risk
https://scielosp.org/pdf/rpsp/2019.v43/e3/en
Keywords. Colorectal neoplasms; rectal neoplasms; obesity; body mass index; meta-analysis. 1. Clarkstown High School North, New City, New. York, United States ...
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https://scielosp.org/pdf/rpsp/2019.v43/e3/en
Keywords. Colorectal neoplasms; rectal neoplasms; obesity; body mass index; meta-analysis. 1. Clarkstown High School North, New City, New. York, United States ...
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14
Association of Body Mass Index With Risk of Early-Onset Colo...
https://journals.lww.com/ajg/Fulltext/2021/11000/Association_of_Body_Mass_Index_With_Risk_of.11.aspx
Incidence of colorectal cancer (CRC) in young adults has been increasing in recent decades in many countries for still widely unclear reasons. Suspected ...
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https://journals.lww.com/ajg/Fulltext/2021/11000/Association_of_Body_Mass_Index_With_Risk_of.11.aspx
Incidence of colorectal cancer (CRC) in young adults has been increasing in recent decades in many countries for still widely unclear reasons. Suspected ...
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15
Assessment of clinicopathological and prognostic relevance of ...
https://onlinelibrary.wiley.com/doi/10.1002/bab.2053
B-cell-specific Moloney leukemia virus insertion site 1 (BMI-1) is one of the stemness markers. The prognostic and clinicopathological ...
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https://onlinelibrary.wiley.com/doi/10.1002/bab.2053
B-cell-specific Moloney leukemia virus insertion site 1 (BMI-1) is one of the stemness markers. The prognostic and clinicopathological ...
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16
Association of Body Mass Index With Colorectal Cancer Risk ...
https://academic.oup.com/jnci/article-abstract/113/1/38/5824300
Each 5 kg/m2 increase in BMI was more strongly associated with colorectal cancer risk for women with the rs4939827-CC genotype (OR = 1.24, 95% CI = 1.16 to 1.32 ...
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https://academic.oup.com/jnci/article-abstract/113/1/38/5824300
Each 5 kg/m2 increase in BMI was more strongly associated with colorectal cancer risk for women with the rs4939827-CC genotype (OR = 1.24, 95% CI = 1.16 to 1.32 ...
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17
Obesity and Cancer Fact Sheet - NCI
https://www.cancer.gov/about-cancer/causes-prevention/risk/obesity/obesity-fact-sheet
High levels of insulin and IGF-1 may promote the development of colon, kidney, prostate, and endometrial cancers (34). People with obesity often ...
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https://www.cancer.gov/about-cancer/causes-prevention/risk/obesity/obesity-fact-sheet
High levels of insulin and IGF-1 may promote the development of colon, kidney, prostate, and endometrial cancers (34). People with obesity often ...
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18
Body Mass Index and Colorectal Cancer - IntechOpen
https://www.intechopen.com/chapters/62128
Cohort studies and meta-analyses strengthened the evidence and demonstrate that obesity increases the risk of colon cancer up to 33% as compared to the risk of ...
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https://www.intechopen.com/chapters/62128
Cohort studies and meta-analyses strengthened the evidence and demonstrate that obesity increases the risk of colon cancer up to 33% as compared to the risk of ...
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19
Hereditary Colorectal Risk Factors - American Cancer Society
https://www.cancer.org/cancer/colon-rectal-cancer/causes-risks-prevention/risk-factors.html
Being overweight raises the risk of colon and rectal cancer in people, but the link seems to be ... About 1% of all colorectal cancers are caused by FAP.
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https://www.cancer.org/cancer/colon-rectal-cancer/causes-risks-prevention/risk-factors.html
Being overweight raises the risk of colon and rectal cancer in people, but the link seems to be ... About 1% of all colorectal cancers are caused by FAP.
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20
Elucidating the Role of BMI1 in Lung and Colon Tumor ...
https://dspace.mit.edu/bitstream/handle/1721.1/143417/kuo-eyskuo-phd-biology-2022-thesis%20.pdf?sequence=1&isAllowed=y
Targeting BMI1 in colon cancer. 38. V. Remaining questions. 39. VI. References. 41. CHAPTER 2: Genetic ablation of Bmi1 in established lung adenocarcinoma ...
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https://dspace.mit.edu/bitstream/handle/1721.1/143417/kuo-eyskuo-phd-biology-2022-thesis%20.pdf?sequence=1&isAllowed=y
Targeting BMI1 in colon cancer. 38. V. Remaining questions. 39. VI. References. 41. CHAPTER 2: Genetic ablation of Bmi1 in established lung adenocarcinoma ...
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21
Expression of Genes Related to Lipid Handling and the ...
https://cancer.jmir.org/2020/1/e16974/
In some cancers, such as colorectal cancer, obesity and high fat intake are known to increase the ... Published on 19.5.2020 in Vol 6, No 1 (2020): Jan-Jun.
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https://cancer.jmir.org/2020/1/e16974/
In some cancers, such as colorectal cancer, obesity and high fat intake are known to increase the ... Published on 19.5.2020 in Vol 6, No 1 (2020): Jan-Jun.
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22
BMI1-KLF4 axis deficiency improves responses to ...
https://www.thegreenjournal.com/article/S0167-8140(20)30348-0/fulltext
High levels of BMI1 have been demonstrated to contribute to the malignant phenotypes of several cancers; however, its relevance in rectal cancer ...
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https://www.thegreenjournal.com/article/S0167-8140(20)30348-0/fulltext
High levels of BMI1 have been demonstrated to contribute to the malignant phenotypes of several cancers; however, its relevance in rectal cancer ...
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23
Polycomb group protein Bmi1 expression in colon cancers ...
https://link.springer.com/article/10.1007/s12032-009-9373-y
The expression of Bmi1 was examined in colorectal carcinoma (n = 98) by using real-time polymerase chain reaction. Expression was correlated ...
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https://link.springer.com/article/10.1007/s12032-009-9373-y
The expression of Bmi1 was examined in colorectal carcinoma (n = 98) by using real-time polymerase chain reaction. Expression was correlated ...
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24
RESEARCH ARTICLE Prognostic Value of FBXO39 and ETS ...
http://journal.waocp.org/article_60723_934eb427cb583381bd1d4d3c2e5363ca.pdf
FBXO39 and ETS-1 Potentialfor Prognostic Markers in Colorectal Cancer Patients ... RT-PCR demonstrated BMI-1 gene expression in both tumor and normal ...
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http://journal.waocp.org/article_60723_934eb427cb583381bd1d4d3c2e5363ca.pdf
FBXO39 and ETS-1 Potentialfor Prognostic Markers in Colorectal Cancer Patients ... RT-PCR demonstrated BMI-1 gene expression in both tumor and normal ...
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25
Hes1 promotes cell proliferation and migration by activating ...
https://www.oncotarget.com/article/5484/text/
Previous reports have showed that Bmi-1 promotes drug resistance and cellular invasion in cancer cells and cancer stem cells [30, 31], moreover, ...
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https://www.oncotarget.com/article/5484/text/
Previous reports have showed that Bmi-1 promotes drug resistance and cellular invasion in cancer cells and cancer stem cells [30, 31], moreover, ...
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26
BMI1 activates WNT signaling in colon cancer by negatively re..|INIS
https://inis.iaea.org/search/search.aspx?orig_q=RN:53044170
Overexpression of BMI1 in primary epithelial colon cells promotes cellular growth and activates WNT pathway, while BMI1 silencing in colon cancer cells ...
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https://inis.iaea.org/search/search.aspx?orig_q=RN:53044170
Overexpression of BMI1 in primary epithelial colon cells promotes cellular growth and activates WNT pathway, while BMI1 silencing in colon cancer cells ...
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27
Regulation of the Potential Marker for Intestinal Cells, Bmi1, by ...
https://www.jbc.org/article/S0021-9258(20)48185-2/fulltext
We found that Wnt signaling indeed regulates the expression of Bmi1 in colon cancer cells. In addition, the expression of Bmi1 in human ...
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https://www.jbc.org/article/S0021-9258(20)48185-2/fulltext
We found that Wnt signaling indeed regulates the expression of Bmi1 in colon cancer cells. In addition, the expression of Bmi1 in human ...
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28
Ring finger 220 promotes the stemness and progression of ...
https://www.tandfonline.com/doi/full/10.1080/21655979.2021.2003664
Colorectal cancer (CRC) is ranked as the third most common malignancy worldwide. ... of colon cancer cells via Ubiquitin specific peptidase 22-BMI1 axis.
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https://www.tandfonline.com/doi/full/10.1080/21655979.2021.2003664
Colorectal cancer (CRC) is ranked as the third most common malignancy worldwide. ... of colon cancer cells via Ubiquitin specific peptidase 22-BMI1 axis.
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29
Bmi-1 promotes the invasion and migration of colon cancer stem ce ...
http://www.ingentaconnect.com/content/sp/ijmm/2016/00000038/00000004/art00025
Recently, mounting evidence has suggested that cancer stem cells (CSCs) and epithelial-mesenchymal transition (EMT) are critical factors in tumor metastasis and ...
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http://www.ingentaconnect.com/content/sp/ijmm/2016/00000038/00000004/art00025
Recently, mounting evidence has suggested that cancer stem cells (CSCs) and epithelial-mesenchymal transition (EMT) are critical factors in tumor metastasis and ...
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30
The Bmi-1 oncoprotein is overexpressed in human colorectal ...
https://europepmc.org/article/med/14732230
The level of Bmi-1 mRNA in the carcinoma tissues was significantly higher than those of the adjacent non-neoplastic colonic mucosal tissues.
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https://europepmc.org/article/med/14732230
The level of Bmi-1 mRNA in the carcinoma tissues was significantly higher than those of the adjacent non-neoplastic colonic mucosal tissues.
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31
Hypericin-Loaded Transferrin Nanoparticles Induce PP2A ...
https://pubs.acs.org/doi/10.1021/acsbiomaterials.9b01844
Hypericin-Loaded Transferrin Nanoparticles Induce PP2A-Regulated BMI1 Degradation in Colorectal Cancer-Specific Chemo-Photodynamic Therapy.
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https://pubs.acs.org/doi/10.1021/acsbiomaterials.9b01844
Hypericin-Loaded Transferrin Nanoparticles Induce PP2A-Regulated BMI1 Degradation in Colorectal Cancer-Specific Chemo-Photodynamic Therapy.
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32
Obesity and Risk of Colorectal Cancer: A Systematic Review ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0053916
Obesity is considered one important risk factor for many types of solid cancers, especially for CRC [56]. Previous reviews have indicated that ...
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0053916
Obesity is considered one important risk factor for many types of solid cancers, especially for CRC [56]. Previous reviews have indicated that ...
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33
Colorectal cancer risk based on extended family ... - CDC stacks
https://stacks.cdc.gov/view/cdc/98492/cdc_98492_DS1.pdf
colorectal cancer; family history; obesity; UPDB; body mass index; ... 115,490 individuals with one or more linked cancer diagnoses; ...
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https://stacks.cdc.gov/view/cdc/98492/cdc_98492_DS1.pdf
colorectal cancer; family history; obesity; UPDB; body mass index; ... 115,490 individuals with one or more linked cancer diagnoses; ...
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34
Immunostaining of Bmi1 and -catenin in colon cancer TMA. A ...
https://www.researchgate.net/figure/Immunostaining-of-Bmi1-and-catenin-in-colon-cancer-TMA-A-colorectal-cancer-CRC-with_fig1_51880252
Download scientific diagram | Immunostaining of Bmi1 and -catenin in colon cancer TMA. A, colorectal cancer (CRC) with strong nuclear immunoreactions of ...
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https://www.researchgate.net/figure/Immunostaining-of-Bmi1-and-catenin-in-colon-cancer-TMA-A-colorectal-cancer-CRC-with_fig1_51880252
Download scientific diagram | Immunostaining of Bmi1 and -catenin in colon cancer TMA. A, colorectal cancer (CRC) with strong nuclear immunoreactions of ...
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35
Expression Patterns for TETs, LGR5 and BMI1 in Cancer Stem ...
https://www.ajmb.org/article?id=10361
BMI1 is a marker of intestinal stem cells able to label quiescent stem cells. G-protein-coupled receptor 5 (LGR5) is also upregulated in CRCs 7. LGR5 may play ...
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https://www.ajmb.org/article?id=10361
BMI1 is a marker of intestinal stem cells able to label quiescent stem cells. G-protein-coupled receptor 5 (LGR5) is also upregulated in CRCs 7. LGR5 may play ...
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36
The relationship between the expression of USP22, BMI1, and ...
https://www.dovepress.com/the-relationship-between-the-expression-of-usp22-bmi1-and-ezh2-in-hepa-peer-reviewed-fulltext-article-OTT
Keywords: hepatocellular carcinoma, USP22, BMI1, EZH2. ... expression of USP22 and BMI1 is closely correlated in colorectal cancer tissues.
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https://www.dovepress.com/the-relationship-between-the-expression-of-usp22-bmi1-and-ezh2-in-hepa-peer-reviewed-fulltext-article-OTT
Keywords: hepatocellular carcinoma, USP22, BMI1, EZH2. ... expression of USP22 and BMI1 is closely correlated in colorectal cancer tissues.
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37
MUC1-C drives stemness in progression of colitis to colorectal ...
https://insight.jci.org/articles/view/137112
We also show in CRC cells that MUC1-C induces cancer stem cell (CSC) markers (BMI1, ALDH1, FOXA1, LIN28B) and the OCT4, SOX2, and NANOG pluripotency factors.
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https://insight.jci.org/articles/view/137112
We also show in CRC cells that MUC1-C induces cancer stem cell (CSC) markers (BMI1, ALDH1, FOXA1, LIN28B) and the OCT4, SOX2, and NANOG pluripotency factors.
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38
Lower Bmi-1 Expression May Predict Longer Survival of Colon ...
https://agris.fao.org/agris-search/search.do?recordID=DJ20220349089
Lower Bmi-1 Expression May Predict Longer Survival of Colon Cancer Patients [2016]. Xiaodong Li; Xiao Zheng; Bin Xu; Dachuan Zhang; et al.
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https://agris.fao.org/agris-search/search.do?recordID=DJ20220349089
Lower Bmi-1 Expression May Predict Longer Survival of Colon Cancer Patients [2016]. Xiaodong Li; Xiao Zheng; Bin Xu; Dachuan Zhang; et al.
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39
The Association Between Metabolic Syndrome and Colorectal ...
https://www.jpmph.org/m/journal/view.php?number=2245
The HR of MetS for colon cancer across BMI categories was 1.12 (95% CI, 1.06 to 1.19), 1.14 (95% CI, 1.08 to 1.20), and 1.16 (95% CI, 1.12 to ...
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https://www.jpmph.org/m/journal/view.php?number=2245
The HR of MetS for colon cancer across BMI categories was 1.12 (95% CI, 1.06 to 1.19), 1.14 (95% CI, 1.08 to 1.20), and 1.16 (95% CI, 1.12 to ...
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40
Bmi-1 promotes the invasion and migration of ... - ProQuest
http://search.proquest.com/openview/860881f5becce7e54c3b0db08900f4f3/1?pq-origsite=gscholar&cbl=2044958
On the whole, our findings suggest that Bmi-1 promotes the invasion and migration of CCSCs through the downregulation of E-cadherin, possibly by inducing EMT.
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http://search.proquest.com/openview/860881f5becce7e54c3b0db08900f4f3/1?pq-origsite=gscholar&cbl=2044958
On the whole, our findings suggest that Bmi-1 promotes the invasion and migration of CCSCs through the downregulation of E-cadherin, possibly by inducing EMT.
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41
BMI1 activates WNT signaling in colon cancer by negatively ...
https://www.osti.gov/biblio/23127408
Abstract. Highlights: • BMI1 is upregulated and activates WNT signaling in colon cancer. • IDAX is a direct target of BMI1 and is downregulated in colon ...
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https://www.osti.gov/biblio/23127408
Abstract. Highlights: • BMI1 is upregulated and activates WNT signaling in colon cancer. • IDAX is a direct target of BMI1 and is downregulated in colon ...
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42
PTC209, a Specific Inhibitor of BMI1, Promotes Cell Cycle ...
https://ar.iiarjournals.org/content/anticanres/40/1/133.full.pdf
in inhibiting the growth of colon, breast, oral cancer cells and cancer-initiating cells ... downregulated the expression of BMI1 in cervical cancer cell.
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https://ar.iiarjournals.org/content/anticanres/40/1/133.full.pdf
in inhibiting the growth of colon, breast, oral cancer cells and cancer-initiating cells ... downregulated the expression of BMI1 in cervical cancer cell.
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43
Oncogenic potential of BMI1: race-based evidence in prostate ...
https://amj.amegroups.com/article/view/4699/5441
Aberrant BMI1 expression has been identified in various human cancers including bladder, skin, prostate, breast, colorectal, ovarian, ...
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https://amj.amegroups.com/article/view/4699/5441
Aberrant BMI1 expression has been identified in various human cancers including bladder, skin, prostate, breast, colorectal, ovarian, ...
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44
Preoperative BMI Affects Long-Term Survival Outcomes After ...
https://www.gastroenterologyadvisor.com/colorectal-neoplasia/preoperative-bmi-affects-long-term-survival-outcomes-after-colorectal-cancer-operation/
Patients with rectal cancer who had a BMI greater than 25 demonstrated significantly better overall survival rates than patients with BMI less ...
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https://www.gastroenterologyadvisor.com/colorectal-neoplasia/preoperative-bmi-affects-long-term-survival-outcomes-after-colorectal-cancer-operation/
Patients with rectal cancer who had a BMI greater than 25 demonstrated significantly better overall survival rates than patients with BMI less ...
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45
Original Article Differences in the gut microbiome by physical ...
https://e-century.us/files/ajcr/12/10/ajcr0145332.pdf
colorectal cancer survivors [1, 2]. In contrast, such a linear relationship has not been con- firmed with BMI and colorectal cancer survival.
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https://e-century.us/files/ajcr/12/10/ajcr0145332.pdf
colorectal cancer survivors [1, 2]. In contrast, such a linear relationship has not been con- firmed with BMI and colorectal cancer survival.
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46
Colorectal cancer: Epidemiology, risk factors, and protective ...
https://www.uptodate.com/contents/colorectal-cancer-epidemiology-risk-factors-and-protective-factors
In the United States, both the incidence and mortality have been slowly but steadily decreasing [1]. Annually, approximately 151,030 new cases ...
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https://www.uptodate.com/contents/colorectal-cancer-epidemiology-risk-factors-and-protective-factors
In the United States, both the incidence and mortality have been slowly but steadily decreasing [1]. Annually, approximately 151,030 new cases ...
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47
PTC-209 is a Specific BMI-1 Inhibitor and Impairs the Tumor ...
https://www.cancer-research-network.com/colorectal-cancer-2/ptc-209-is-a-specific-bmi-1-inhibitor-and-impairs-the-tumor-microenvironment/2021-06-10/
BMI-1 is part of the polycomb repressive complex 1 (PRC1). There is a statistically significant correlation between the high frequency of BMI-1- ...
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https://www.cancer-research-network.com/colorectal-cancer-2/ptc-209-is-a-specific-bmi-1-inhibitor-and-impairs-the-tumor-microenvironment/2021-06-10/
BMI-1 is part of the polycomb repressive complex 1 (PRC1). There is a statistically significant correlation between the high frequency of BMI-1- ...
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48
Body-mass index and risk of 22 specific cancers - The Lancet
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)60892-8/fulltext
BMI was positively associated with liver (1·19, 1·12–1·27), colon (1·10, 1·07–1·13), ovarian (1·09, 1.04–1.14), and postmenopausal breast ...
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https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)60892-8/fulltext
BMI was positively associated with liver (1·19, 1·12–1·27), colon (1·10, 1·07–1·13), ovarian (1·09, 1.04–1.14), and postmenopausal breast ...
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49
Colon cancer - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/colon-cancer/symptoms-causes/syc-20353669
Diabetes. People with diabetes or insulin resistance have an increased risk of colon cancer. Obesity. People who are obese have an increased ...
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https://www.mayoclinic.org/diseases-conditions/colon-cancer/symptoms-causes/syc-20353669
Diabetes. People with diabetes or insulin resistance have an increased risk of colon cancer. Obesity. People who are obese have an increased ...
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50
What Is the Link Between Obesity and Colorectal Cancer?
https://www.cancersupportcommunity.org/blog/2019/07/what-link-between-obesity-and-colorectal-cancer
The adverse effects of obesity include conditions like type II diabetes, hypertension, and cardiovascular disease. However, obesity has also ...
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https://www.cancersupportcommunity.org/blog/2019/07/what-link-between-obesity-and-colorectal-cancer
The adverse effects of obesity include conditions like type II diabetes, hypertension, and cardiovascular disease. However, obesity has also ...
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51
BMI1 | Cancer Genetics Web - CancerIndex
http://www.cancerindex.org/geneweb/BMI1.htm
BMI-1 mRNA and positive protein levels were correlated with the National Institutes of Health (NIH) risk grade, tumor diameter and infiltration, and metastasis.
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http://www.cancerindex.org/geneweb/BMI1.htm
BMI-1 mRNA and positive protein levels were correlated with the National Institutes of Health (NIH) risk grade, tumor diameter and infiltration, and metastasis.
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52
Physical activity reduces colorectal cancer risk ... - bioRxiv
https://www.biorxiv.org/content/10.1101/798470v1.full.pdf
Title: Physical activity reduces colorectal cancer risk independent of BMI—A two-sample. Mendelian randomisation study. Authors: Xiaomeng Zhanga,1, ...
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https://www.biorxiv.org/content/10.1101/798470v1.full.pdf
Title: Physical activity reduces colorectal cancer risk independent of BMI—A two-sample. Mendelian randomisation study. Authors: Xiaomeng Zhanga,1, ...
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53
Regulation of the potential marker for intestinal cells, Bmi1, by β ...
https://scholars.uky.edu/en/publications/regulation-of-the-potential-marker-for-intestinal-cells-bmi1-by-%CE%B2
In addition, the expression of Bmi1 in human colon cancers is ... We also found that Bmi1 regulates histone ubiquitination and is required for colon cancer ...
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https://scholars.uky.edu/en/publications/regulation-of-the-potential-marker-for-intestinal-cells-bmi1-by-%CE%B2
In addition, the expression of Bmi1 in human colon cancers is ... We also found that Bmi1 regulates histone ubiquitination and is required for colon cancer ...
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54
Association of Body Mass Index with Survival in Asian Patients ...
https://www.e-crt.org/m/journal/view.php?number=3323
Obesity is a well-known risk factor of colorectal cancer (CRC) [1–3]. Proinflammatory factors, immune suppression, and changes in the metabolic ...
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https://www.e-crt.org/m/journal/view.php?number=3323
Obesity is a well-known risk factor of colorectal cancer (CRC) [1–3]. Proinflammatory factors, immune suppression, and changes in the metabolic ...
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55
Early-life obesity and adulthood colorectal cancer risk
https://iris.paho.org/handle/10665.2/49674
Results. High early-life BMI was associated with a 39% increased risk of CRC in adult men (RR = 1.39, 95%CI = 1.20 – 1.62 ...
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https://iris.paho.org/handle/10665.2/49674
Results. High early-life BMI was associated with a 39% increased risk of CRC in adult men (RR = 1.39, 95%CI = 1.20 – 1.62 ...
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56
How does obesity cause colorectal cancer? | WCRF ...
https://www.wcrf.org/researchwefund/are-metabolites-associated-with-obesity-causing-colorectal-cancer/
There is now strong evidence that having more body fat increases an individual's risk of developing cancers of the colon and rectum (collectively known as ...
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https://www.wcrf.org/researchwefund/are-metabolites-associated-with-obesity-causing-colorectal-cancer/
There is now strong evidence that having more body fat increases an individual's risk of developing cancers of the colon and rectum (collectively known as ...
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57
Exercise Can Help Fight Colon Cancer, Even If Patient Is Obese
https://www.usnews.com/news/health-news/articles/2022-11-17/exercise-can-help-fight-colon-cancer-even-if-patient-is-obese
"Inflammation is a key process that drives colorectal cancer. We know a high BMI [body mass index] causes inflammation around the body," ...
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https://www.usnews.com/news/health-news/articles/2022-11-17/exercise-can-help-fight-colon-cancer-even-if-patient-is-obese
"Inflammation is a key process that drives colorectal cancer. We know a high BMI [body mass index] causes inflammation around the body," ...
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58
The Prognostic Value of Polycomb Group Protein BMI1 in Stage II ...
https://forskning.ruc.dk/en/publications/the-prognostic-value-of-polycomb-group-protein-bmi1-in-stage-ii-c
BMI1 protein expression was assessed by immunohistochemistry in a retrospective patient cohort consisting of 144 stage II colon cancer patients.
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https://forskning.ruc.dk/en/publications/the-prognostic-value-of-polycomb-group-protein-bmi1-in-stage-ii-c
BMI1 protein expression was assessed by immunohistochemistry in a retrospective patient cohort consisting of 144 stage II colon cancer patients.
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59
A pooled analysis of FFCD trials - European Journal of Cancer
https://www.ejcancer.com/article/S0959-8049(18)30780-9/pdf
1. Introduction. Obesity is a major health concern worldwide. The ... Adjuvant Colon Cancer End Points database revealed.
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https://www.ejcancer.com/article/S0959-8049(18)30780-9/pdf
1. Introduction. Obesity is a major health concern worldwide. The ... Adjuvant Colon Cancer End Points database revealed.
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60
Bowel cancer risk | Cancer Research UK
https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/bowel-cancer/risk-factors
The estimated lifetime risk of being diagnosed with bowel cancer is 1 in ... [1,2] 11% of bowel cancer cases in the UK are caused by overweight and obesity.
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https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/bowel-cancer/risk-factors
The estimated lifetime risk of being diagnosed with bowel cancer is 1 in ... [1,2] 11% of bowel cancer cases in the UK are caused by overweight and obesity.
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61
The effect of body mass index on location of recurrence and ...
https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2020;volume=16;issue=8;spage=176;epage=182;aulast=Sakin
Hypertension and diabetes ratios were found to be significantly correlated with BMI. In this study, the incidence of right colon cancer was ...
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https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2020;volume=16;issue=8;spage=176;epage=182;aulast=Sakin
Hypertension and diabetes ratios were found to be significantly correlated with BMI. In this study, the incidence of right colon cancer was ...
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62
Prognostic and predictive role of body mass index (BMI) in ...
https://www.annalsofoncology.org/article/S0923-7534(19)58798-1/fulltext
Obesity is associated with an increased risk of development and recurrence of colorectal cancer. The role of obesity in mCRC patients (pts) is still unclear, ...
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https://www.annalsofoncology.org/article/S0923-7534(19)58798-1/fulltext
Obesity is associated with an increased risk of development and recurrence of colorectal cancer. The role of obesity in mCRC patients (pts) is still unclear, ...
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63
Progastrin production transitions from Bmi1+/Prox1+ to ...
https://hal.archives-ouvertes.fr/hal-03090781/document
Progastrin is an unprocessed soluble peptide precursor with a well-described tumor-promoting role in colorectal cancer.
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https://hal.archives-ouvertes.fr/hal-03090781/document
Progastrin is an unprocessed soluble peptide precursor with a well-described tumor-promoting role in colorectal cancer.
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64
Body Fatness and Cancer — Viewpoint of the IARC Working ...
https://www.nejm.org/doi/full/10.1056/nejmsr1606602
Obesity can further be divided into class 1 (BMI, 30.0 to 34.9), ... of weight gain for cancers of the colon, esophagus (adenocarcinoma), ...
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https://www.nejm.org/doi/full/10.1056/nejmsr1606602
Obesity can further be divided into class 1 (BMI, 30.0 to 34.9), ... of weight gain for cancers of the colon, esophagus (adenocarcinoma), ...
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65
Fiber-rich Foods to Treat Obesity and Prevent Colon Cancer
https://clinicaltrials.gov/ct2/show/NCT04780477
Experimental: High Fiber Diet (HFD) pre-portioned entrées for two meals/d in mos. 1-3, and one meal/d in mos. 4-6. Participants continue on ...
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https://clinicaltrials.gov/ct2/show/NCT04780477
Experimental: High Fiber Diet (HFD) pre-portioned entrées for two meals/d in mos. 1-3, and one meal/d in mos. 4-6. Participants continue on ...
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66
Can Weight Loss Reduce the Risk of Colon Cancer?
https://www.gastrohealthpartners.com/can-weight-loss-reduce-the-risk-of-colon-cancer/
Being obese, or having a BMI of 30.0 and above, has been considered a risk factor of developing colorectal cancer for years.
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https://www.gastrohealthpartners.com/can-weight-loss-reduce-the-risk-of-colon-cancer/
Being obese, or having a BMI of 30.0 and above, has been considered a risk factor of developing colorectal cancer for years.
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67
Exercise can improve outcomes for colon cancer patients
https://www.upi.com/Health_News/2022/11/18/exercise-colon-cancer-obesity/6831668711148/
"Inflammation is a key process that drives colorectal cancer. We know a high BMI [body mass index] causes inflammation around the body," ...
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https://www.upi.com/Health_News/2022/11/18/exercise-colon-cancer-obesity/6831668711148/
"Inflammation is a key process that drives colorectal cancer. We know a high BMI [body mass index] causes inflammation around the body," ...
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68
Colorectal Cancer: Risk Factors and Prevention - Cancer.Net
https://www.cancer.net/cancer-types/colorectal-cancer/risk-factors-and-prevention
Colorectal cancer can occur in young adults and teenagers, but the majority of colorectal cancers occur in people older than 50. For colon cancer, the average ...
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https://www.cancer.net/cancer-types/colorectal-cancer/risk-factors-and-prevention
Colorectal cancer can occur in young adults and teenagers, but the majority of colorectal cancers occur in people older than 50. For colon cancer, the average ...
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69
Expression level of Bmi-1 oncoprotein is associated with ... - Wikidata
https://www.wikidata.org/wiki/Q54449349
Expression level of Bmi-1 oncoprotein is associated with progression and prognosis in colon cancer. scientific article published on 19 December 2009.
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https://www.wikidata.org/wiki/Q54449349
Expression level of Bmi-1 oncoprotein is associated with progression and prognosis in colon cancer. scientific article published on 19 December 2009.
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70
Colon cancer Information | Mount Sinai - New York
https://www.mountsinai.org/health-library/diseases-conditions/colon-cancer
Colon cancer. Colorectal cancer; Cancer - colon; Rectal cancer; Cancer - rectum; Adenocarcinoma - colon; Colon - adenocarcinoma; Colon carcinoma.
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https://www.mountsinai.org/health-library/diseases-conditions/colon-cancer
Colon cancer. Colorectal cancer; Cancer - colon; Rectal cancer; Cancer - rectum; Adenocarcinoma - colon; Colon - adenocarcinoma; Colon carcinoma.
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71
Risk factors for colorectal cancer | Canadian Cancer Society
https://cancer.ca/en/cancer-information/cancer-types/colorectal/risks
A family history of colorectal cancer means that one or more close blood ... Colorectal cancer occurs more often in people who are overweight or obese than ...
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https://cancer.ca/en/cancer-information/cancer-types/colorectal/risks
A family history of colorectal cancer means that one or more close blood ... Colorectal cancer occurs more often in people who are overweight or obese than ...
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72
How does obesity cause cancer? | MD Anderson Cancer Center
https://www.mdanderson.org/publications/focused-on-health/how-does-obesity-cause-cancer.h27Z1591413.html
What's less clear is how exactly one leads to the other. ... shows that excess body fat increases your risk for several cancers, including colorectal, ...
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https://www.mdanderson.org/publications/focused-on-health/how-does-obesity-cause-cancer.h27Z1591413.html
What's less clear is how exactly one leads to the other. ... shows that excess body fat increases your risk for several cancers, including colorectal, ...
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73
Colon Cancer Risk Factors | Johns Hopkins Medicine
https://www.hopkinsmedicine.org/health/conditions-and-diseases/colon-cancer/colon-cancer-risk-factors
The following lifestyle factors can increase your risk of developing colon or rectal cancer: A sedentary lifestyle (physical inactivity). Being overweight or ...
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https://www.hopkinsmedicine.org/health/conditions-and-diseases/colon-cancer/colon-cancer-risk-factors
The following lifestyle factors can increase your risk of developing colon or rectal cancer: A sedentary lifestyle (physical inactivity). Being overweight or ...
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74
Thin Colorectal Cancer Patients Have Shorter Survival Than ...
https://corporate.dukehealth.org/news/thin-colorectal-cancer-patients-have-shorter-survival-obese-patients
DURHAM, N.C. – Although being overweight with a high body-mass index (BMI) has long been associated with a higher risk for colorectal cancer ...
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https://corporate.dukehealth.org/news/thin-colorectal-cancer-patients-have-shorter-survival-obese-patients
DURHAM, N.C. – Although being overweight with a high body-mass index (BMI) has long been associated with a higher risk for colorectal cancer ...
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75
Study finds a positive impact of exercise on the gut ...
https://www.news-medical.net/news/20221114/Study-finds-a-positive-impact-of-exercise-on-the-gut-microbiome-of-cancer-patients.aspx
"Inflammation is a key process that drives colorectal cancer. We know a high BMI causes inflammation around the body," Ulrich says. "Obesity is ...
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https://www.news-medical.net/news/20221114/Study-finds-a-positive-impact-of-exercise-on-the-gut-microbiome-of-cancer-patients.aspx
"Inflammation is a key process that drives colorectal cancer. We know a high BMI causes inflammation around the body," Ulrich says. "Obesity is ...
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76
Generation of CD8+ Cytotoxic T Cell Clones Recognizing BMI1 ...
https://ashpublications.org/blood/article-abstract/112/11/2909/59800
Furthermore, higher BMI1 expression in the tumorigenic cancer stem cell population ... 1 Ovarian ca., 3 Breast ca., 4 Melanoma, 1 Colon ca., 1 Pancreas ca.
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https://ashpublications.org/blood/article-abstract/112/11/2909/59800
Furthermore, higher BMI1 expression in the tumorigenic cancer stem cell population ... 1 Ovarian ca., 3 Breast ca., 4 Melanoma, 1 Colon ca., 1 Pancreas ca.
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77
Obesity - World Health Organization (WHO)
https://www.who.int/health-topics/obesity
Obesity is also associated with some cancers, including endometrial, breast, ovarian, prostate, liver, gallbladder, kidney and colon. The risk of these ...
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https://www.who.int/health-topics/obesity
Obesity is also associated with some cancers, including endometrial, breast, ovarian, prostate, liver, gallbladder, kidney and colon. The risk of these ...
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78
Upregulation of BMI1-suppressor miRNAs (miR-200c, miR-203 ...
https://pure.fujita-hu.ac.jp/en/publications/upregulation-of-bmi1-suppressor-mirnas-mir-200c-mir-203-during-te
Upregulation of BMI1-suppressor miRNAs (miR-200c, miR-203) during terminal ... of colon cancer cells, in vitro organoid formation by normal colon epithelial ...
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https://pure.fujita-hu.ac.jp/en/publications/upregulation-of-bmi1-suppressor-mirnas-mir-200c-mir-203-during-te
Upregulation of BMI1-suppressor miRNAs (miR-200c, miR-203) during terminal ... of colon cancer cells, in vitro organoid formation by normal colon epithelial ...
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79
Overweight/Obesity-Associated Cancers
https://www.dshs.texas.gov/tcr/data/obesity-associated-cancers.aspx
Overweight/obesity is known to increase the risk of at least 13 different types of cancer: post-menopausal breast cancer, colorectal cancer, ...
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https://www.dshs.texas.gov/tcr/data/obesity-associated-cancers.aspx
Overweight/obesity is known to increase the risk of at least 13 different types of cancer: post-menopausal breast cancer, colorectal cancer, ...
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80
Lower Bmi-1 Expression May Predict Longer Survival of Colon ...
https://ur.booksc.eu/book/63522679/683ff3
Lower Bmi-1 Expression May Predict Longer Survival of Colon Cancer Patients | Li, Xiaodong; Zheng, Xiao; Xu, Bin; Zhang, Dachuan; Xu, Yun; Xie, Quanqin; Hu, ...
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https://ur.booksc.eu/book/63522679/683ff3
Lower Bmi-1 Expression May Predict Longer Survival of Colon Cancer Patients | Li, Xiaodong; Zheng, Xiao; Xu, Bin; Zhang, Dachuan; Xu, Yun; Xie, Quanqin; Hu, ...
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81
Obesity and Diabetes - Page 242 - Google Books Result
https://books.google.com/books?id=bQtUnmj7Y1EC&pg=PA242&lpg=PA242&dq=bmi+1+colon+cancer&source=bl&ots=N5TMVjGxab&sig=ACfU3U2SHT7Mk9u4fxBcLl1eHehruXJ6Og&hl=en&sa=X&ved=2ahUKEwjd97OnpMP7AhWahf0HHXJPBVsQ6AF6BQitAhAD
although the association was somewhat stronger in men (Table 1). ... Overall, an increased risk of colorectal cancer with increasing BMI has been observed ...
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https://books.google.com/books?id=bQtUnmj7Y1EC&pg=PA242&lpg=PA242&dq=bmi+1+colon+cancer&source=bl&ots=N5TMVjGxab&sig=ACfU3U2SHT7Mk9u4fxBcLl1eHehruXJ6Og&hl=en&sa=X&ved=2ahUKEwjd97OnpMP7AhWahf0HHXJPBVsQ6AF6BQitAhAD
although the association was somewhat stronger in men (Table 1). ... Overall, an increased risk of colorectal cancer with increasing BMI has been observed ...
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82
Journal of the National Cancer Institute: JNCI.
https://books.google.com/books?id=Brvp3HSU1DkC&pg=PA920&lpg=PA920&dq=bmi+1+colon+cancer&source=bl&ots=fBTP7n9xZe&sig=ACfU3U07iJ6bsVwGHxktz9xYhAyyc8X_VA&hl=en&sa=X&ved=2ahUKEwjd97OnpMP7AhWahf0HHXJPBVsQ6AF6BQihAhAD
Body Size and Risk of Colon and Rectal Cancer in the European Prospective ... colorectal cancer has been examined in many epidemiologic studies ( 1-30 ) .
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https://books.google.com/books?id=Brvp3HSU1DkC&pg=PA920&lpg=PA920&dq=bmi+1+colon+cancer&source=bl&ots=fBTP7n9xZe&sig=ACfU3U07iJ6bsVwGHxktz9xYhAyyc8X_VA&hl=en&sa=X&ved=2ahUKEwjd97OnpMP7AhWahf0HHXJPBVsQ6AF6BQihAhAD
Body Size and Risk of Colon and Rectal Cancer in the European Prospective ... colorectal cancer has been examined in many epidemiologic studies ( 1-30 ) .
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83
Understanding Pathophysiology, Canadian Edition - E-Book
https://books.google.com/books?id=oRRSDwAAQBAJ&pg=PA283&lpg=PA283&dq=bmi+1+colon+cancer&source=bl&ots=kc5nbqi4Vb&sig=ACfU3U282hGPVW7wj6ShWg8QdJznHl5WuQ&hl=en&sa=X&ved=2ahUKEwjd97OnpMP7AhWahf0HHXJPBVsQ6AF6BQiqAhAD
Obesity Obesity in most developed countries (and in urban areas of many ... Emerging, however, are three main factors related to obesity and cancer: (1) the ...
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https://books.google.com/books?id=oRRSDwAAQBAJ&pg=PA283&lpg=PA283&dq=bmi+1+colon+cancer&source=bl&ots=kc5nbqi4Vb&sig=ACfU3U282hGPVW7wj6ShWg8QdJznHl5WuQ&hl=en&sa=X&ved=2ahUKEwjd97OnpMP7AhWahf0HHXJPBVsQ6AF6BQiqAhAD
Obesity Obesity in most developed countries (and in urban areas of many ... Emerging, however, are three main factors related to obesity and cancer: (1) the ...
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84
Advanced Nutrition and Dietetics in Obesity
https://books.google.com/books?id=ky5ADwAAQBAJ&pg=PA57&lpg=PA57&dq=bmi+1+colon+cancer&source=bl&ots=ZOtfhp_bTU&sig=ACfU3U2ZcvTG0UL3zk_ByxyaOuOnQJ34KQ&hl=en&sa=X&ved=2ahUKEwjd97OnpMP7AhWahf0HHXJPBVsQ6AF6BQipAhAD
stronger associations were found between BMI and colon cancer risk for men than ... cell growth factors (insulin‐like growth factor (IGF‐1) and IGF‐binding ...
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https://books.google.com/books?id=ky5ADwAAQBAJ&pg=PA57&lpg=PA57&dq=bmi+1+colon+cancer&source=bl&ots=ZOtfhp_bTU&sig=ACfU3U2ZcvTG0UL3zk_ByxyaOuOnQJ34KQ&hl=en&sa=X&ved=2ahUKEwjd97OnpMP7AhWahf0HHXJPBVsQ6AF6BQipAhAD
stronger associations were found between BMI and colon cancer risk for men than ... cell growth factors (insulin‐like growth factor (IGF‐1) and IGF‐binding ...
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85
Abeloff's Clinical Oncology E-Book - Page 97 - Google Books Result
https://books.google.com/books?id=9ExgDAAAQBAJ&pg=PA97&lpg=PA97&dq=bmi+1+colon+cancer&source=bl&ots=97MFqgCbN-&sig=ACfU3U22QLRWfttauRj01AOBYRuHNMwF6A&hl=en&sa=X&ved=2ahUKEwjd97OnpMP7AhWahf0HHXJPBVsQ6AF6BQirAhAD
Infection of the cells with a bmi-1 retrovirus completely rescues the proliferative ... in colon cancer by inactivation of the protein degradation pathway, ...
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https://books.google.com/books?id=9ExgDAAAQBAJ&pg=PA97&lpg=PA97&dq=bmi+1+colon+cancer&source=bl&ots=97MFqgCbN-&sig=ACfU3U22QLRWfttauRj01AOBYRuHNMwF6A&hl=en&sa=X&ved=2ahUKEwjd97OnpMP7AhWahf0HHXJPBVsQ6AF6BQirAhAD
Infection of the cells with a bmi-1 retrovirus completely rescues the proliferative ... in colon cancer by inactivation of the protein degradation pathway, ...
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86
Colorectal cancer: Moderate exercise may improve gut health
https://www.medicalnewstoday.com/articles/first-study-looks-at-exercises-impact-on-the-microbiome-in-people-with-cancer
Overall, lower gut microbial diversity was observed among inactive, obese, and overweight/ obese/inactive participants. Moreover, gut biome ...
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https://www.medicalnewstoday.com/articles/first-study-looks-at-exercises-impact-on-the-microbiome-in-people-with-cancer
Overall, lower gut microbial diversity was observed among inactive, obese, and overweight/ obese/inactive participants. Moreover, gut biome ...
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