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1 Virtue ethics of clinical research - PMC - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384398/
A widely accepted idea of clinical science is that it seeks the truth and that the knowledge acquired should be of benefit to patients.[1] Therefore, as ...
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2 Taking Respect Seriously: Clinical Research and the ...
https://academic.oup.com/jmp/article/43/3/342/4994289
This article reevaluates informed consent in clinical research in light of this challenge. It rebuts the main points the critics raise and shows ...
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3 Research Philosophy - Amgen
https://www.amgen.com/science/clinical-trials/information-for-healthcare-professionals/research-philosophy
Research Philosophy. At Amgen, we aspire to be the best human therapeutics company. Clinical research at Amgen is built upon the framework of the Amgen ...
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4 What Makes Clinical Research Ethical? - Dartmouth
https://www.dartmouth.edu/cphs/docs/jama-article.pdf
research. Drawing on the basic philosophies underlying major codes, dec- ... work for evaluating the ethics of clinical research studies: (1) value—.
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5 Introduction: Why Is Philosophy Relevant for Clinical Practice?
https://link.springer.com/chapter/10.1007/978-3-030-41239-5_1
It is a tool for understanding some of the philosophical motivations and rationality behind the way medicine and healthcare are studied, ...
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6 Journal of Medicine and Philosophy
https://www.cmu.edu/dietrich/philosophy/docs/london/London--2DogmasResearchEthics.pdf
Unlike clinical medicine, the purpose of clinical research is not to administer treatment to individual patients; it is to investigate ...
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7 Learn About Clinical Studies - ClinicalTrials.gov
https://clinicaltrials.gov/ct2/about-studies/learn
A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of ...
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8 Philosophers assess randomized clinical trials: The need for ...
https://www.sciencedirect.com/science/article/pii/0197245689900664
In recent years a growing number of professional philosophers have joined in the controversy over ethical aspects of randomized clinical trials (RCTs).
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9 Philosophy - GreenLight Clinical
https://www.greenlightclinical.com/philosophy/
We are ever mindful of the clinical trial impact on our patients & their families. It is vitally important to us to make our patients feel valued, respected and ...
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10 Doctor of Philosophy in Applied Clinical Research
https://www.utsouthwestern.edu/education/school-of-health-professions/programs/applied-clinical-research/
The primary goal of the Ph.D. Program in Applied Clinical Research is to provide rigorous research training for health professionals aspiring to pursue ...
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11 Clinical trials - World Health Organization (WHO)
https://www.who.int/health-topics/clinical-trials
Clinical trials are a type of research that studies new tests and treatments and evaluates their effects on human health outcomes. People volunteer to take ...
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12 Navigating ethical challenges of conducting randomized ...
https://peh-med.biomedcentral.com/articles/10.1186/s13010-022-00115-3
The contemporary frameworks for clinical research require informed consent for research participation that includes disclosure of material ...
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13 What is clinical trial? - Definition from WhatIs.com - TechTarget
https://www.techtarget.com/searchhealthit/definition/clinical-trial
A clinical trial, also known as a clinical research study, is a protocol to evaluate the effects and efficacy of experimental medical treatments or ...
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14 Step 3: Clinical Research - FDA
https://www.fda.gov/patients/drug-development-process/step-3-clinical-research
While preclinical research answers basic questions about a drug's safety, it is not a substitute for studies of ways the drug will interact ...
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15 Medical Philosophy: A Philosophical Analysis of Patient Self ...
https://www.amazon.com/Medical-Philosophy-Philosophical-Self-Perception-Diagnostics/dp/3838209753
This innovative book clarifies the distinction between philosophy of medicine and medical philosophy, expanding the focus from the 'knowing that' of the first ...
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16 Philosophy and Ethics - University of Mississippi Medical Center
https://www.umc.edu/Research/Centers-and-Institutes/Centers/Center-for-Bioethics-and-Medical-Humanities/About-the-Center-for-Bioethics-and-Medical-Humanities/Areas/Philosophy%20and%20Ethics.html
Medical Philosophy is the application of philosophy (the systematic analysis of arguments regarding the fundamental nature of reality, knowledge, and value) to ...
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17 Current epistemological problems in evidence based medicine
https://jme.bmj.com/content/30/2/131
Evidence based medicine has been a topic of considerable controversy in medical and health care circles over its short lifetime, because of the claims made by ...
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18 Democratizing Strategies for Industry-Funded Medical Research
https://www.cambridge.org/core/journals/philosophy-of-science/article/democratizing-strategies-for-industryfunded-medical-research-a-cautionary-tale/9680AE49F91F2E3E45669AA0E91BF5CD
Hence, these cases show a misalignment among the different goals of research. The ethical and epistemic goal of acquiring more accurate ...
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19 Clinical research - Wikipedia
https://en.wikipedia.org/wiki/Clinical_research
Clinical research is a branch of healthcare science that determines the safety and effectiveness (efficacy) of medications, devices, diagnostic products and ...
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20 Romanell Center for Clinical Ethics and the Philosophy of ...
https://www.buffalo.edu/romanell.html
Bishop's research interests include bioethics, philosophy of medicine, history of philosophy, medicine and spirituality. His latest book is Biopolitics ...
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21 Articulating and Responding to Uncertainties in Clinical ...
https://www.tandfonline.com/doi/full/10.1080/03605310701255719
The author finally shows that there is a predictable relation between [acknowledgement of] uncertainty (the moral principle) on which trials are based and the ...
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22 Clinical trial Definition & Meaning - Merriam-Webster
https://www.merriam-webster.com/dictionary/clinical%20trial
The meaning of CLINICAL TRIAL is a scientifically controlled study of the safety and effectiveness of a therapeutic agent (such as a drug or ...
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23 Medicine, Philosophy of
https://iep.utm.edu/medicine/
empiricism, sound medical thinking and judgments, robust medical explanations, and valid diagnostic and therapeutic knowledge. Next, it will address the vast ...
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24 Ethical Principles for Medical Research Involving Human ...
https://www.encyclopedia.com/science/science-magazines/science-philosophy-and-practice-ethical-principles-medical-research-involving-human-subjects
Science Philosophy and Practice: Ethical Principles for Medical Research Involving Human SubjectsIntroductionMedicine is both an art and a science.
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25 Philosophy of Medicine - Bibliography - PhilPapers
https://philpapers.org/browse/philosophy-of-medicine
The insurgence of evidence-based methods to medical research over the past two decades, however, has challenged the framing of the goals of medical science.
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26 Definition of phase IV clinical trial - National Cancer Institute
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/phase-iv-clinical-trial
NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.
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27 Studies in Medical Philosophy - Liberal Arts - Series
https://www.ibidem.eu/en/reihen/kultur/studies-in-medical-philosophy.html
The possible need of philosophy in medicine will be searched in terms of elucidation and stimulation of certain aspects of medical research and clinical ...
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28 About Clinical Studies - Clinical Trials - Mayo Clinic Research
https://www.mayo.edu/research/clinical-trials/about-clinical-studies
Treatment studies test new combinations of drugs and new approaches to surgery, radiation therapy and complementary medicine. The role of inheritance or genetic ...
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29 Quality by Design for Clinical Trials - SOCRA Blog
https://www.socra.org/blog/quality-by-design-for-clinical-trials/
This article explores myths about quality and provides a general overview of the principles and philosophy of quality by design for clinical ...
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30 What types of clinical research are there? - Antidote.me
http://www.antidote.me/blog/what-types-of-clinical-research-are-there
Clinical trials provide the best available data with which to make healthcare decisions and are considered the gold standard in the development ...
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31 The ethics of global clinical trials
https://www.embopress.org/doi/10.15252/embr.201540398
Nevertheless, clinical trials and the research and health care that accompany them can directly benefit patients, in particular those who would otherwise have ...
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32 Philosophy of Molecular Medicine : Foundational Issues in ...
https://www.routledge.com/Philosophy-of-Molecular-Medicine-Foundational-Issues-in-Research-and-Practice/Boniolo-Nathan/p/book/9780367736699
Philosophy of Molecular Medicine: Foundational Issues in Theory and Practice aims at a systematic investigation of a number of foundational issues in the ...
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33 NIH Collaboratory Rethinking Clinical Trials - The Living ...
https://rethinkingclinicaltrials.org/
Pragmatic clinical trials that address questions of major public health importance and provide proof of concept for innovative pragmatic research designs. CORES.
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34 Bioethics and philosophy of science | PPts | Journals | Videos
https://www.walshmedicalmedia.com/scholarly/bioethics-and-philosophy-of-science--journals-articles-ppts-list-691.html
Journal of Clinical Research & Bioethics · Bioethics and philosophy of science · Useful Links · Contact Us · Connect.
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35 Protectionism in Research Involving Human Subjects
https://repository.upenn.edu/cgi/viewcontent.cgi?article=1019&context=bioethics_papers
From the subjects' point of view, a philosophy that calls for ease of access to clinical research emerged in the. 1980s, and I will allude to it later in ...
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36 Clinical Trials - MedlinePlus
https://medlineplus.gov/clinicaltrials.html
The plan describes what will be done in the study, how it will be conducted, and why each part of the study is necessary. Each study has its own ...
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37 Clinical Trials Transformation Initiative - CTTI
https://ctti-clinicaltrials.org/
Build Better, Faster Clinical Trials. · Design with a Quality Approach · Enhance Patient Engagement · Build Digital Health Trials · Support Investigators & Sites.
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38 Exploitation and Developing Countries: The Ethics of Clinical ...
https://ndpr.nd.edu/reviews/exploitation-and-developing-countries-the-ethics-of-clinical-research/
The discussion of clinical research ethics, which is especially thorough and informative, discusses informed consent, randomized clinical trials ...
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39 Critical Aspects of a Sustainable Clinical Research Program in ...
https://ascopubs.org/doi/full/10.1200/EDBK_238485
Exemplary clinical trial sites should seek to enroll at least 10% of their patients on clinical trials. Achieving this goal requires commitment ...
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40 IACT Health Clinical Research Trials - Be A Medical Hero
https://iacthealth.com/
We are a clinical research firm with locations across Georgia and in Virginia dedicated to creating outstanding clinical trial experiences.
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41 Philosophy of Medicine
https://philosophy.wustl.edu/philosophy-medicine
Philosophy of medicine is an investigation into what doctors know, and how they know it. This course will investigate the following questions: What is ...
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42 Clarifying the Meaning of Clinically Meaningful Benefit in ...
https://jamanetwork.com/journals/jama/fullarticle/2757036
Clarifying the Meaning of Clinically Meaningful Benefit in Clinical Research: Noticeable Change vs Valuable Change ... Recent years have witnessed ...
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43 Utilizing a logic model to identify clinical research problems
https://www.dovepress.com/utilizing-a-logic-model-to-identify-clinical-research-problems-a-lesso-peer-reviewed-fulltext-article-NRR
As one of the assignments in the philosophy of science course, DNP students are required to critically consider a clinical or health care ...
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44 Clinical Trials - Novartis
https://www.novartis.com/clinicaltrials
Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. These studies ensure that an ...
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45 INTRODUCTION TO THE SPECIAL ISSUE ON PHILOSOPHY ...
https://eujap.uniri.hr/introduction-to-the-special-issue-on-philosophy-of-medicine/
Research in philosophy of medicine uses tools and theoretical approaches from different areas of philosophy. Traditionally, philosophical contributions ...
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46 Philosophy of Medicine, Volume 16 - 1st Edition - Elsevier
https://www.elsevier.com/books/philosophy-of-medicine/gabbay/978-0-444-51787-6
This volume covers a wide range of conceptual, epistemological and methodological issues in the philosophy of science raised by reflection upon medical ...
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47 Study a Doctor of Philosophy (PhD) in Clinical Translation
https://www.flinders.edu.au/study/courses/doctor-philosophy-phd-clinical-translation
At the Flinders Health and Medical Research Institute (FHMRI) our clinical researchers work to develop and implement new methods for the ...
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48 Clinical Research MAS - UCSF Graduate Division
https://graduate.ucsf.edu/clinical-mas
The overarching philosophy of the program is to combine theoretical instruction with practical application. Many of the required courses integrate the student's ...
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49 Types of Clinical Research - Theoretical Models and ...
https://rushu.libguides.com/c.php?g=694134&p=4919625
Descriptive; Experimental; Exploratory; Historical; Longitudinal; Meta-Analysis; Mixed Methods; Observational; Philosophical. Action Research ...
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50 History and Philosophy of the Center
https://www2.rockefeller.edu/ccts/about/history
Subsequently, in 1953, the National Institutes of Health (NIH) established the Clinical Center as a medical facility devoted to medical research and in 1960 the ...
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51 PhD in Clinical and Translational Science Program - ICRE
https://www.icre.pitt.edu/ClinTransPhD/index.html
Doctor of Philosophy in Clinical and Translational Science ... The Institute for Clinical Research Education at the University of Pittsburgh has designed ...
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52 Phases of Clinical Trials - MD Anderson Cancer Center
https://www.mdanderson.org/patients-family/diagnosis-treatment/clinical-trials/phases-of-clinical-trials.html
The clinical trials process is designed to ensure that new treatments are better than existing therapies. If your care team recommends that you join a ...
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53 Clinical Trials - Anthropology - Oxford Bibliographies
https://www.oxfordbibliographies.com/view/document/obo-9780199766567/obo-9780199766567-0242.xml
Clinical trials are tests of safety and efficacy for drugs, vaccines, and diagnostics. Methods by with which trials are conducted include ...
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54 The Ethical Implications of Clinical Trials in Low- and Middle ...
https://www.americanbar.org/groups/crsj/publications/human_rights_magazine_home/the-truth-about-science/the-ethical-implications-of-clinical-trials/
Uncertainty about the degree of risks and benefits associated with a treatment being tested is implicit in clinical research. The risks might be ...
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55 Understanding Clinical Trials - Mayfield Clinic
https://mayfieldclinic.com/pe-clintrial.htm
Phase I determines the safety of a treatment that showed positive results in laboratory and animal studies. · Phase II tests the effectiveness (efficacy) of a ...
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56 What Are The Steps Involved In Clinical Trials?
https://conquestresearch.com/blog/what-are-the-steps-involved-in-clinical-trials/
The research and development process of clinical trials involves testing new medical treatments and devices through a series of steps.
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57 What Evidence in Evidence-Based Medicine? - jstor
https://www.jstor.org/stable/10.1086/341855
†Send requests for reprints to John Worrall, Department of Philosophy, Logic and ... reliable method of conducting clinical research” (1983, 5).
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58 Clinical Trials | Patient Resources | UT Southwestern Medical ...
https://utswmed.org/patient-resources/clinical-trials/
Participation in a clinical study means you have volunteered to enroll in that study. Participation in a clinical study is always voluntary, meaning ...
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59 Clinical trials - Merck.com
https://www.merck.com/research/clinical-trials/
Our medical advances can only happen through the efforts of many people, especially the patients who volunteer for clinical trials. They are our partners in ...
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60 Phases of clinical trials - Cancer Research UK
https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/what-clinical-trials-are/phases-of-clinical-trials
Clinical trials testing new treatments are divided into different stages, called phases. The earliest phase trials may look at whether a drug is ...
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61 Research Problems and Methods in the Philosophy of Medicine
https://core.ac.uk/download/pdf/161891247.pdf
Research Problems and Methods—Philosophy of Medicine. 37. 37 in clinical research over the last 30 years” and its continued reliance instead ...
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62 Examination of Clinical Trial Costs and Barriers for Drug ...
https://aspe.hhs.gov/reports/examination-clinical-trial-costs-barriers-drug-development-0
Pharmaceutical companies conduct clinical trials for many reasons. The most obvious goal of clinical trials is to demonstrate safety and efficacy to gain ...
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63 Clinical trials - NHS
https://www.nhs.uk/conditions/clinical-trials/
A clinical trial compares the effects of 1 treatment with another. It may involve patients, healthy people, or both.
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64 The role of philosophy in medical practice
https://www.spandidos-publications.com/10.3892/etm.2019.7944
To practice evidence‑based medicine is both a practical and a philosophical decision. Thus, philosophy is a great companion of medicine, as it ...
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65 How do clinical trials work? - Medical News Today
https://www.medicalnewstoday.com/articles/278779
Clinical trials aim to find out whether a medical strategy, treatment, or device is safe and effective for humans to use or consume. Trials consist of four ...
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66 What is a Clinical Study? - Definition & Explanation
https://study.com/academy/lesson/what-is-a-clinical-study-definition-lesson-quiz.html
A clinical study is a scientific examination of how a treatment for an illness or mental disorder works in humans. Importance of Clinical ...
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67 Clinical Trial Phases: What Happens in Phase 0, I, II, III, and IV
https://www.healthline.com/health/clinical-trial-phases
Clinical trials are a way to test new methods of diagnosing, treating, or preventing health conditions. The goal is to determine whether something is both safe ...
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68 Advanced Seminar in Philosophy of Medicine
https://www.philosophy.ox.ac.uk/advanced-seminar-in-philosophy-of-medicine
Whether the treatments we take are believed to be 'effective' often depends on whether they are better than 'placebos' in clinical trials. Understanding what ...
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69 42 CFR Part 11 -- Clinical Trials Registration and Results ...
https://www.ecfr.gov/current/title-42/chapter-I/subchapter-A/part-11
For purposes of this part, “primary outcome” has the same meaning as primary outcome measure. Principal investigator means the individual who is responsible for ...
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70 The Ethics of Clinical Research in the Third World | NEJM
https://www.nejm.org/doi/full/10.1056/nejm199709183371209
An essential ethical condition for a randomized clinical trial comparing two treatments for a disease is that there be no good reason for ...
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71 The Philosophy of Evidence‐Based Medicine
https://onlinelibrary.wiley.com/doi/book/10.1002/9781444342673
Seeking to address questions raised by critics, The Philosophy of ... of Clinical Trials: Resolving the Philip's Paradox (Pages: 63-79).
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72 Jeremy Howick, The Philosophy of Evidence-Based Medicine ...
https://kiej.georgetown.edu/jeremy-howick-philosophy-evidence-based-medicine-wiley-blackwell-2011/
However, Howick introduces his rule of evidence: comparative clinical studies (or observational studies more generally) provide good evidence ...
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73 Opinion | Do Clinical Trials Work? - The New York Times
https://www.nytimes.com/2013/07/14/opinion/sunday/do-clinical-trials-work.html
Gilbert's study was the gold standard. The earlier studies had each been “single-arm,” in the lingo of clinical trials, meaning there had been ...
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74 Phases of Clinical Trials | Cancer.Net
https://www.cancer.net/research-and-advocacy/clinical-trials/phases-clinical-trials
Clinical trials are research studies that include human volunteers. Before they start a clinical trial, doctors must prove there is a chance that the new ...
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75 How does Standard-Of-Care Affect Clinical Trials?
https://www.news-medical.net/life-sciences/How-does-Standard-Of-Care-Affect-Clinical-Trials.aspx
Clinical trials aim to test the efficacy and safety of a new investigational medicinal product (IMP). This is done by conducting trials that ...
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76 clinical research | History and Philosophy of Science
https://sites.utexas.edu/hps/tag/clinical-research/
Tag Archives: clinical research · Past Event: · Friday, April 3 · Sponsored by the University of Houston and Rice University.
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77 Clinical trials in human medicines
https://www.ema.europa.eu/en/human-regulatory/research-development/clinical-trials-human-medicines
The regulation of clinical trials aims to ensure that the rights, safety and well-being of trial participants are protected and the results of clinical trials ...
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78 The evolution of clinical trials: Can we address the challenges ...
https://journals.sagepub.com/doi/full/10.1177/1740774518755058
Transparency in clinical trials also benefits patients and the public. Availability of information on clinical trials and their results builds trust (no trial ...
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79 The Question of Clinical Equipoise and Patients' Best Interests
https://journalofethics.ama-assn.org/article/question-clinical-equipoise-and-patients-best-interests/2015-12
In its canonical formulation, clinical equipoise stipulates that a randomized controlled trial (RCT) is only ethical insofar as there exists, at ...
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80 Pivotal Clinical Trials: Frequently Asked Questions - Sofpromed
https://www.sofpromed.com/pivotal-clinical-trials-frequently-asked-questions
A pivotal clinical trial seeks to demonstrate the efficacy of a new experimental drug in order to obtain its marketing approval by ...
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81 Principles of Clinical Ethics and Their Application to Practice
https://www.karger.com/Article/FullText/509119
The requirements of an informed consent for a medical or surgical procedure, or for research, are that the patient or subject (i) must be competent to ...
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82 Master of Science in Clinical Research - Rush University
https://www.rushu.rush.edu/graduate-college/academic-programs/master-science-clinical-research
Now accepting Masters of Science in Clinical Research applications for fall 2017. Learn more about Clinical Research program admissions and deadlines or ...
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83 How should we understand “clinical equipoise” when doing ...
https://blogs.worldbank.org/impactevaluations/how-should-we-understand-clinical-equipoise-when-doing-rcts-development
This kind of study can only be carried out ethically if the intervention being assessed is in equipoise, meaning that the medical community ...
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84 Clinical Trials and Screening: What You Need to Know
https://www.radiologyinfo.org/en/info/screening-clinical-trials
A clinical trial is a type of research study that tests how well new medical techniques work in people. Individual research trials are designed to answer ...
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85 Master of Science in Clinical Research
https://catalog.ku.edu/medicine/population-health/ms/
The University of Kansas Master of Science in Clinical Research program (MS-CR) is a 33 credit hour graduate program with the student's thesis serving as ...
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86 Philosophy of Molecular Medicine | Foundational Issues in ...
https://www.taylorfrancis.com/books/edit/10.4324/9781315674162/philosophy-molecular-medicine-giovanni-boniolo-marco-nathan
Philosophy of Molecular Medicine: Foundational Issues in Theory and Practice aims at a systematic investigation of a number of foundational ...
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87 Why Most Clinical Research Is Not Useful | PLOS Medicine
https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002049
The term “clinical research” is meant to cover all types of investigation that address questions on the treatment, prevention, diagnosis/ ...
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88 Philosophy of Evidence-Based Medicine - Oxford Bibliographies
https://philarchive.org/archive/HOWPOE-2
of comparative clinical studies (including observational studies and ... “A Philosophical Analysis of the Evidence-Based Medicine Debate.
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89 Degrees and programs | Graduate and Professional Admissions
https://gpadmissions.osu.edu/programs/programs.aspx
... of Philosophy. African American and African Studies ... of Philosophy. Clinical Research ... of Philosophy. East Asian Studies Interdisciplinary Program.
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90 Frontiers in Psychology
https://www.frontiersin.org/journals/psychology
Paving the way for a greater understanding of human behavior. The most cited journal in its field, exploring psychological sciences - from clinical research to ...
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91 What is Cognitive Behavioral Therapy?
https://www.apa.org/ptsd-guideline/patients-and-families/cognitive-behavioral
It is important to emphasize that advances in CBT have been made on the basis of both research and clinical practice. Indeed, CBT is an approach for which ...
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92 What is a clinical trial and how does it work? - Roche
https://www.roche.com/innovation/process/clinical-trials/about
Ethical clinical research is guided by the principles of nonmalificence, respect, beneficence and justice. Nonmalificence is the duty to cause no harm. This ...
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