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1 LXRs regulate ER stress and inflammation through dynamic ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889491/
Promotion of Lpcat3 activity ameliorates endoplasmic reticulum (ER) stress induced by saturated free fatty acids in vitro or by hepatic lipid accumulation in ...
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2 Endoplasmic Reticulum Stress Affects Cholesterol ... - MDPI
https://www.mdpi.com/2072-6643/12/10/3088/htm
Tunicamycin-induced ER stress caused liver injury; promoted the accumulation of cholesterol and triglycerides; inhibited the expression of LXRα, ABCA1 and ABCG1 ...
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3 Protective Functions of Liver X Receptor α in Established ...
https://www.ahajournals.org/doi/10.1161/JAHA.120.018455
LXR activation alleviates apoptosis and defective efferocytosis as well as endoplasmic reticulum stress in carotid vulnerable plaques. LXRα ...
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4 LXRs Regulate ER Stress and Inflammation through ... - CORE
https://core.ac.uk/download/pdf/81119881.pdf
hypothesized that LXRs might reduce ER stress by increasing ... LXRs and Lpcat3 Attenuate Lipid-Induced ER Stress.
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5 Endoplasmic reticulum stress impairs cholesterol efflux and ...
https://www.jlr.org/content/55/1/94.full.pdf
hepatic endoplasmic reticulum (ER) stress, which affects neutral lipid metabolism. ... LXR is activated by ER stress and does not account for de-.
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6 LXRs Protect DRG Neurons from High-Fat Diet–Induced ER ...
https://diabetesjournals.org/diabetes/article/67/Supplement_1/553-P/60486/LXRs-Protect-DRG-Neurons-from-High-Fat-Diet
Nuclear LXRs control gene programs in liver cells, adipocytes, and macrophages to regulate lipid metabolism, inflammation and ER stress ...
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7 LXRs Regulate ER Stress and Inflammation ... - ResearchGate
https://www.researchgate.net/publication/258425841_LXRs_Regulate_ER_Stress_and_Inflammation_through_Dynamic_Modulation_of_Membrane_Phospholipid_Composition
Request PDF | LXRs Regulate ER Stress and Inflammation through Dynamic Modulation of Membrane Phospholipid Composition | The fatty acyl ...
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8 Nuclear Receptors Resolve Endoplasmic Reticulum Stress to ...
https://www.e-dmj.org/journal/view.php?number=461
Chronic endoplasmic reticulum (ER) stress culminating in ... Although direct studies of LXR activation in vivo are complicated by its potent ...
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9 LXRs regulate ER stress and inflammation ... - Diagenode
https://www.diagenode.com/en/publications/view/1737
LXRs regulate ER stress and inflammation through dynamic modulation of membrane phospholipid composition. Rong X, Albert CJ, Hong C, Duerr MA, ...
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10 Minireview: Endoplasmic Reticulum Stress: Control in Protein ...
https://academic.oup.com/mend/article/27/3/384/2615014
Endoplasmic reticulum (ER) stress is a regulatory mechanism that allows cells ... liver X receptor (LXR), pregnane X receptor (PXR), PPARs, etc, (48, 49).
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11 Crosstalk Between Hypoxia and ER Stress Response - Frontiers
https://www.frontiersin.org/articles/10.3389/fimmu.2019.02951/full
Crosstalk Between Hypoxia and ER Stress Response: A Key Regulator of Macrophage Polarization · LXR Activation Induces a Proinflammatory Trained Innate Immunity- ...
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12 Lipid Synthesis Is Required to Resolve Endoplasmic ...
https://www.atsjournals.org/doi/10.1165/rcmb.2017-0340OC
Endoplasmic reticulum (ER) stress is evident in the alveolar epithelium of ... and liver X receptor (LXR)-α in DMSO- or TM-exposed cells.
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13 IFN-g aggravates neointimal hyperplasia by inducing ...
https://faseb.onlinelibrary.wiley.com/doi/pdf/10.1096/fj.201700327R
endoplasmic reticulum stress and apoptosis in ... dependent LXR-a degradation induced by IFN-g promoted ER stress and apoptosis in macrophages, which.
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14 Small heterodimer partner (SHP) aggravates ER stress in ...
https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-021-00747-1
It remains unclear, however, how mutant LRRK2 influence ER stress to ... (LXRs) decrease saturated fatty acid-induced ER stress in primary ...
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15 Purple Perilla Extracts Allay ER Stress in Lipid-Laden ... - PLOS
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110581
The lipid-lowering compound pravastatin ameliorates ER stress in cultured ... The liver X receptor (LXR) agonist T091317 was purchased by ...
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16 Endoplasmic Reticulum Stress and Lipid Metabolism - Hindawi
https://www.hindawi.com/journals/bri/2012/841362/
ER-stress-dependent dysregulation of lipid metabolism may lead to ... liver X receptor (LXR), peroxisome-proliferator-activated receptors (PPARs), ...
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17 Insulin Dissociates the Effects of Liver X ... - Archive ouverte HAL
https://hal.archives-ouvertes.fr/hal-01391796/
However, insulin was not required for LXR alpha to modulate the phospholipid profile, or to suppress genes in the ER stress or inflammation pathways.
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18 GRP78 expression inhibits insulin and ER stress–induced ...
https://www.jci.org/articles/view/37007
In order to analyze the effect of ER stress on SREBP-1c proteolytic cleavage, hepatocytes were incubated for 6 h in the presence of the LXR agonist ...
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19 Insulin Dissociates the Effects of Liver X Receptor on ...
https://www.jbc.org/article/S0021-9258(20)36143-3/pdf
of LXR on cholesterol efflux, inflammation, and ER stress from the negative effects on lipogenesis. Obesity and diabetes have risen to ...
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20 Endoplasmic reticulum stress and lipids in health and diseases
https://doi.org/10.1016/j.plipres.2022.101198
ER stress activates the UPR by sensing two independent sources of stress. ... This feedback may be bypassed by the antagonism of LXR with steroid hormone ...
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21 Endoplasmic reticulum stress‑induced cell death as a ...
https://www.spandidos-publications.com/10.3892/ijo.2021.5240
If ER stress is continuous, the unfolded protein response (UPR) is not ... Karpel-Massler G and Siegelin MD: Activation of LXR receptors and ...
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22 RIP140 in Stress Response of the Brain
https://www.jneurology.com/articles/rip140-in-stress-response-of-the-brain.pdf
Keywords: RIP140; NRIP1; Brain; Psychological stress; ER stress; ... interacts with LXR to enhance the expression of sterol regulatory.
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23 Exendin-4 inhibits glucolipotoxic ER stress in pancreatic β ...
https://joe.bioscientifica.com/view/journals/joe/216/3/343.xml
Chronic treatment with high glucose (HG), as well as ER stress inducers, ... DNA binding activity by preventing LXR/RXR dimerization (Yamamoto et al. 2007).
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24 IFN-γ aggravates neointimal hyperplasia by ... - EPA - HERO
https://hero.epa.gov/hero/index.cfm/reference/details/reference_id/7020129
Treatment with ER stress inhibitor, 4-phenylbutyric acid (4-PBA), and LXR agonist, T0901317 (T0), alleviated IFN-γ-induced apoptosis in ...
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25 Liver gene expression analysis reveals endoplasmic reticulum ...
https://journals.physiology.org/doi/full/10.1152/physiolgenomics.00139.2007
Liver gene expression analysis reveals endoplasmic reticulum stress and metabolic dysfunction in SCD1-deficient mice fed a very low-fat diet.
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26 Full article: Elimination of endoplasmic reticulum stress and ...
https://www.tandfonline.com/doi/full/10.3109/07853890.2012.700116
Positive ER stress-eliminating effects of the ER-activating therapies include ... LXR-activating compounds reduce amyloid load and improve cognitive ...
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27 Insulin Dissociates the Effects of Liver X Receptor ... - HAL-Inria
https://hal.inria.fr/hal-01391796/
The nuclear hormone receptor liver X receptor (LXR) is induced by insulin and ... effects of LXR on cholesterol efflux, inflammation, and ER stress from the ...
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28 A guide to understanding endoplasmic reticulum stress in ...
https://mediatum.ub.tum.de/doc/1659033/1659033.pdf
function and metabolic adaptation and, therefore disturbed ER function, known as “ER stress,” is a key feature of metabolic disorders.
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29 ATF6α downregulation of PPARα promotes lipotoxicity ...
https://www.kidney-international.org/article/S0085-2538(18)30779-8/fulltext
On ER stress, ATF6α is transported to the Golgi apparatus and cleaved by ... as shown by increased expression of LXR and Abca1 (Figure 1f), ...
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30 NR1H3 - Oxysterols receptor LXR-alpha | UniProtKB - UniProt
https://www.uniprot.org/uniprotkb/Q13133/entry
Induces LPCAT3-dependent phospholipid remodeling in endoplasmic reticulum (ER) ... Via LPCAT3 also counteracts lipid-induced ER stress response and ...
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31 Homocysteine-induced endoplasmic reticulum stress activates ...
https://www.biorxiv.org/content/10.1101/2021.09.08.459498v1.full
Thus, Bhmt KO mice have increased ER stress compared to their WT counterparts. ... Fasting-induced FGF21 is repressed by LXR activation via ...
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32 Endoplasmic Reticulum Stress in Macrophages - MDPI
https://mdpi-res.com/d_attachment/biomedicines/biomedicines-08-00210/article_deploy/biomedicines-08-00210.pdf
Abstract: The endoplasmic reticulum (ER) stress is an important event in the ... Homeostasis and Liver X Receptor (LXR) in Atherosclerosis.
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33 ER Stress in Diabetic Peripheral Neuropathy
https://deepblue.lib.umich.edu/bitstream/handle/2027.42/140287/ars.2013.5807.pdf?sequence=1
improved understanding of how ER stress contributes to peripheral nerve dysfunction in diabetes ... with an altered lipid pattern: protective effects of LXR.
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34 Endoplasmic reticulum stress response in nonalcoholic fatty ...
https://www.environmentmed.org/article.asp?issn=2468-5690;year=2018;volume=3;issue=2;spage=31;epage=37;aulast=Ali
ER stress response also causes insulin resistance and inflammation and in the ... in cholesterol efflux and PPAR-LXR-ABCA1/CYP7A1-mediated bile synthesis.
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35 Endothelial cells, endoplasmic reticulum stress and oxysterols
https://iris.uniroma1.it/retrieve/handle/11573/1006614/1186406/Lucchetti_Endothelial-cells_2017.pdf
tion, LXR is reportedly to regulate ER stress by dynamically modulating the incorporation of polyunsaturated fatty acids into phospholipids.
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36 CREating a SCAP-less liver keeps SREBPs pinned in the ER ...
http://genesdev.cshlp.org/content/15/15/1873.full.html
(2001) Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in ret hepatoma cells requires endogenous LXR ligands. Proc. Natl. Acad. Sci.
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37 Endoplasmic Reticulum Stress in Health and Disease - Springer
https://link.springer.com/content/pdf/10.1007/978-94-007-4351-9.pdf
The book focuses on physiological responses of ER stress in pancreatic β cells ... Endoplasmic Reticulum Stress and the Unfolded Protein.
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38 Reducing endoplasmic reticulum stress through a ... - Gale
https://go.gale.com/ps/i.do?id=GALE%7CA214458012&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=10788956&p=AONE&sw=w
Macrophages show endoplasmic reticulum (ER) stress when exposed to ... of LXR-α also restored sensitivity to palmitate-induced ER stress and ...
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39 Endoplasmic reticulum stress impairs ... - Research Collection
https://www.research-collection.ethz.ch/bitstream/handle/20.500.11850/77254/2/J.LipidRes.-2014-R%C3%B6hrl-94-103%281%29.pdf
To address if ER stress regulates ABCA1 expres- sion via LXR in HepG2 cells, we compared expression of. ABCA1 with ABCG5 and IDOL, which are established LXR.
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40 (PDF) Erratum: Reducing endoplasmic reticulum stress through a ...
https://www.academia.edu/20726287/Erratum_Reducing_endoplasmic_reticulum_stress_through_a_macrophage_lipid_chaperone_alleviates_atherosclerosis
Erratum: Reducing endoplasmic reticulum stress through a macrophage lipid ... to ER stress and atherosclerosis through p2a LXRE fa T aP2–LXR-α crosstalk.
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41 UCLA - eScholarship.org
https://escholarship.org/uc/item/93c9r39k
Conversely, Lpcat3 knockdown in liver exacerbates ER stress and inflammation. ... during lipid stress and identify Lpcat3 as an important mediator of LXRs ...
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42 Deficiency in Lysophosphatidylcholine Acyltransferase 3 ...
https://www.gastrojournal.org/article/S0016-5085(15)01006-9/abstract
LPCAT3 is also a target of liver X receptor (LXR), ... which regulates endoplasmic reticulum (ER) stress and inflammation through the ...
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43 Lpcat3-dependent production of arachidonoyl phospholipids ...
https://elifesciences.org/articles/06557
Moreover, we showed that the ability of the LXR-Lpcat3 pathway to promote unsaturation of membrane lipids was protective against ER stress ...
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44 搜索
https://www.x-mol.com/paper/1390656603139231744?adv
However, whether ER stress can modulate cholesterol metabolism by LXRα in ... with tunicamycin and LXR-623 (an agonist of LXRα) alone or in combination.
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45 Stressed About Atherosclerosis? | Science Signaling
https://www.science.org/doi/10.1126/scisignal.2101ec399
PBA reduced atherosclerotic lesions, and macrophage ER stress and ... activity of nuclear receptor LXR, a transcriptional activator of Scd1, ...
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46 palmitate-induced er stress: Topics by Science.gov
https://www.science.gov/topicpages/p/palmitate-induced+er+stress
Resveratrol Enhances Palmitate-Induced ER Stress and Apoptosis in Cancer Cells ... X receptor (LXR) agonist reinforces the hypothesis that RSV-mediated ...
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47 TREM2-dependent lipid droplet biogenesis in phagocytes is ...
https://rupress.org/jem/article/218/10/e20210227/212588/TREM2-dependent-lipid-droplet-biogenesis-in
Alleviating ER stress in TREM2-deficient mice restores lipid droplet biogenesis and ... One protective factor is the liver X receptor (LXR), ...
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48 Resveratrol Enhances Palmitate-Induced ER Stress ... - Figshare
https://figshare.com/articles/dataset/_Resveratrol_Enhances_Palmitate_Induced_ER_Stress_and_Apoptosis_in_Cancer_Cells_/1255171
Moreover, the lipotoxicity reversion induced by eicosapentaenoic acid (EPA) or by a liver X receptor (LXR) agonist reinforces the hypothesis ...
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49 Reducing endoplasmic reticulum stress through a ...
https://facultyopinions.com/article/1282044
Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis. Erbay E et al. Nature Medicine.
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50 N-acetylcysteine prevents endoplasmic reticulum stress ...
https://www.atherosclerosis-journal.com/article/S0021-9150(14)01422-1/abstract
... kidney disease increases endoplasmic reticulum stress (ERS). ... from all experimental groups together with 1 μM T0901317, LXR agonist.
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51 FATP4 inactivation in cultured macrophages attenuates M1 ...
https://portlandpress.com/biochemj/article/478/10/1861/228461/FATP4-inactivation-in-cultured-macrophages
FATP4 deficiency in mouse BMDMs alleviates ER stress-induced ... As Lxr regulates genes important for not only lipid metabolism but also ...
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52 HDL inhibits endoplasmic reticulum stress-induced apoptosis ...
https://www.zora.uzh.ch/190125/1/J._Lipid_Res.-2020-Yalcinkaya-492-504.pdf
The quantity of cellular cholesterol determines the activity of transcription factors, such as SREBPs and LXRs (14). The crucial role of both SREBP2 and LXRs as ...
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53 Digital Commons@Becker
https://digitalcommons.wustl.edu/cgi/viewcontent.cgi?article=10808&context=open_access_pubs
Unexpectedly, we found that the LXR agonist but not ISRIB overcomes ... ethanol-mediated LTP inhibition also involves neuronal ER stress re-.
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54 Endoplasmic reticulum stress causes insulin resistance by ...
https://www.molbiolcell.org/doi/abs/10.1091/mbc.E18-01-0013
Endoplasmic reticulum (ER) stress inhibits activation of AKT by insulin by depleting insulin receptors and interferes with the delivery of ...
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55 LXR-α-H00A_2020 Wuxi Biortus Biosciences Co. Ltd.
https://en.wuxibiortus.com/Products_Details/197.html
Alias: Oxysterols receptor LXR-alpha,Liver X receptor alpha,Nuclear receptor subfamily ... Via LPCAT3 also counteracts lipid-induced ER stress response and ...
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56 LXR-B Antibody - WB, E - Buy Now! |Abcepta
https://www.abcepta.com/products/ASC11054-LXR-B-Antibody
Via LPCAT3 also counteracts lipid-induced ER stress response and inflammation, likely by modulating SRC kinase membrane compartmentalization and limiting ...
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57 Award Information | HHS TAGGS
https://taggs.hhs.gov/Detail/AwardDetail?arg_AwardNum=R43HL140712&arg_ProgOfficeCode=130
... (LXR-a/ß) agonist T0901317 (1) effectively reduced proteostasis in the lung epithelium, as visualized by changes in multiple relevant ER stress markers, ...
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58 ER Stress and HIPK2 Activation in ALS - YouTube
https://www.youtube.com/watch?v=RB9o-sramfw
Jul 6, 2016 —
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59 Apolipoprotein E - Wikipedia
https://en.wikipedia.org/wiki/Apolipoprotein_E
Apolipoprotein E (APOE) is a protein involved in the metabolism of fats in the body of ... negative regulation of blood coagulation · response to oxidative stress ...
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60 IFN-γ aggravates neointimal hyperplasia by inducing endoplasmic ...
https://ur.booksc.eu/book/66662884/884cc4?switchLanguage=ur
IFN-γ aggravates neointimal hyperplasia by inducing endoplasmic reticulum stress and apoptosis in macrophages by promoting ubiquitin-dependent liver X ...
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61 PERK, IRE1: Method of Enhancing Immunotherapy Using ER ...
https://moffitt.org/research-science/academic-and-industry-partnerships/office-of-innovation/available-technologies/immunotherapies/20ma005-perk-ire1-method-of-enhancing-immunotherapy-using-er-stress-pathway-inhibitors/
Studies have demonstrated that two major ER stress response pathways, (inositol-requiring enzyme 1) IRE1α-XBP13,4 and (PKR-like endoplasmic-reticulum (ER) ...
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62 Video: Watching how cells deal with stress - Phys.org
https://phys.org/news/2022-06-video-cells-stress.html
Inositol-requiring enzyme 1 alpha (IRE1α)-dependent processing and endoplasmic reticulum (ER) association of XBP1u transcripts during stress ...
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63 Untitled
https://yearshandhandtreat.de/video/446/896945359.html
... monika tesao romantic film er sucking. spreds each a cure torments, ... a a shaved clit. stress and tits fuck orders ebony and watching tits her suck ...
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64 Reactive Oxygen Species (ROS), Nanoparticles, and ...
https://books.google.com/books?id=W9PVDwAAQBAJ&pg=PA676&lpg=PA676&dq=er+stress+lxr&source=bl&ots=2aKtylL9jK&sig=ACfU3U1S_MFYUOVjB8Xtq8ivvnEqJIrmHw&hl=en&sa=X&ved=2ahUKEwi_jamgxsT7AhU7kIkEHZR0DpwQ6AF6BQjdARAD
... X receptor (LXR) signaling coupled sterol metabolism to T-cell lymphocyte proliferation in ... Nanoparticles, and ER Stress-Induced Cell Death Mechanisms.
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65 geb.uni-giessen.de/geb/biblio.php?source_opus=1006...
http://geb.uni-giessen.de/geb/biblio.php?source_opus=10065&export=ris
TY - THES T1 - Endoplasmic Reticulum (ER)-stress signalling in the alveolar epithelium A1 - Hühn,Martin Y1 - 2013/09/23 N2 - Endoplasmic Reticulum ...
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66 Cellular Stress and Inflammation: How the Immune System ...
https://books.google.com/books?id=MVctEAAAQBAJ&pg=PA63&lpg=PA63&dq=er+stress+lxr&source=bl&ots=pMkGTaF7J8&sig=ACfU3U0Tc_oIsaTBJ3bJr31NTaw1PRbA6A&hl=en&sa=X&ved=2ahUKEwi_jamgxsT7AhU7kIkEHZR0DpwQ6AF6BQjTARAD
The innate immune response under the control of the LXR pathway. ... LXRs regulate ER stress and inflammation through dynamic modulation of membrane ...
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67 Bone Marrow Adiposity: Establishing Harmonized, Mechanistic ...
https://books.google.com/books?id=Jx0REAAAQBAJ&pg=RA1-PA22&lpg=RA1-PA22&dq=er+stress+lxr&source=bl&ots=xCDUvJzExs&sig=ACfU3U06jy2vZO2bWKwvHtloeGS21uSzaw&hl=en&sa=X&ved=2ahUKEwi_jamgxsT7AhU7kIkEHZR0DpwQ6AF6BQjUARAD
We further reveal for the first time that LXRs activation totally counteracts the ... SFA may provoke cell death by induction of an ER stress as Palm ...
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68 Engineering & Contracting
https://books.google.com/books?id=JEmb0mnjkIAC&pg=PA202&lpg=PA202&dq=er+stress+lxr&source=bl&ots=yevq75KQBk&sig=ACfU3U2zJVc5OFA8z4pwNEj8XG5m-l5d0w&hl=en&sa=X&ved=2ahUKEwi_jamgxsT7AhU7kIkEHZR0DpwQ6AF6BQjVARAD
er eccentricity of the load measured from the center of the pillar ( in inches ) . In Beams . f = extreme fibre stress - i . e . , stress at the extreme ...
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69 Publications - Thibault Lab
http://www.thibaultlab.com/publications.html
Unfolded protein response and lipid homeostasis in Caenorhabditis elegans and Saccharomyces cerevisiae. Endoplasmic reticulum stress and metabolic diseases.
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