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1
Management of aminoglycosides in the intensive care unit
https://pubmed.ncbi.nlm.nih.gov/20837630/
Clinical application includes the treatment of bacteremia, endocarditis, health-care and nosocomial pneumonias, intra-abdominal infections, and others.
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https://pubmed.ncbi.nlm.nih.gov/20837630/
Clinical application includes the treatment of bacteremia, endocarditis, health-care and nosocomial pneumonias, intra-abdominal infections, and others.
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2
Aminoglycosides for the treatment of septic shock - Critical Care
https://ccforum.biomedcentral.com/articles/10.1186/s13054-020-03284-9
Aminoglycoside treatment was associated with worse outcomes, including increased requirements for renal replacement therapy during the ICU stay ...
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https://ccforum.biomedcentral.com/articles/10.1186/s13054-020-03284-9
Aminoglycoside treatment was associated with worse outcomes, including increased requirements for renal replacement therapy during the ICU stay ...
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3
Management of aminoglycosides in the intensive care unit. | Profiles ...
https://profiles.umassmed.edu/profile/76523
Radigan EA, Gilchrist NA, Miller MA. Management of aminoglycosides in the intensive care unit. J Intensive Care Med. 2010 Nov-Dec; 25(6):327-42.
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https://profiles.umassmed.edu/profile/76523
Radigan EA, Gilchrist NA, Miller MA. Management of aminoglycosides in the intensive care unit. J Intensive Care Med. 2010 Nov-Dec; 25(6):327-42.
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4
An international survey on aminoglycoside practices in ...
https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-021-00834-4
Short courses of high AG doses are mainly used in ICU patients with septic shock, although wide variability in AG usage is reported. We could ...
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https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-021-00834-4
Short courses of high AG doses are mainly used in ICU patients with septic shock, although wide variability in AG usage is reported. We could ...
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5
Aminoglycosides in the Intensive Care Unit - MDPI
https://www.mdpi.com/2079-6382/10/5/507
Background: Although aminoglycosides are often used as treatment for Gram-negative infections, optimal dosing regimens remain unclear, especially in ICU ...
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https://www.mdpi.com/2079-6382/10/5/507
Background: Although aminoglycosides are often used as treatment for Gram-negative infections, optimal dosing regimens remain unclear, especially in ICU ...
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6
Aminoglycoside use and intensive care unit-acquired weakness
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0230181
The relationship between aminoglycoside use and intensive care unit (ICU)-acquired weakness remains controversial. In the present study, ...
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0230181
The relationship between aminoglycoside use and intensive care unit (ICU)-acquired weakness remains controversial. In the present study, ...
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7
Standard dosing of amikacin and gentamicin in critically ill ...
https://www.jvsmedicscorner.com/ICU-Inflammation_and_infection_files/Standard%20dosing%20of%20amikacin%20and%20gentamicin%20in%20critically%20ill%20patients%20results%20in%20variable%20and%20subtherapeutic%20concentrations.pdf
Low peak plasma concentrations (Cmax) of amikacin and gentamicin are reported in intensive care unit. (ICU) patients after administration of the first dose.
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https://www.jvsmedicscorner.com/ICU-Inflammation_and_infection_files/Standard%20dosing%20of%20amikacin%20and%20gentamicin%20in%20critically%20ill%20patients%20results%20in%20variable%20and%20subtherapeutic%20concentrations.pdf
Low peak plasma concentrations (Cmax) of amikacin and gentamicin are reported in intensive care unit. (ICU) patients after administration of the first dose.
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8
Aminoglycosides in the Intensive Care Unit - Preprints
https://www.preprints.org/manuscript/202104.0416/v1
Background Although aminoglycosides are often used as treatment for Gram-Negative infections, optimal dosing regimens remains unclear, ...
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https://www.preprints.org/manuscript/202104.0416/v1
Background Although aminoglycosides are often used as treatment for Gram-Negative infections, optimal dosing regimens remains unclear, ...
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9
Evaluation of aminoglycosides utilization in intensive care ...
http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1885-642X2019000300009
Early and appropriate treatment of patients in intensive care unit (ICU) is critical when managing infections, which could help to reduce ...
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http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1885-642X2019000300009
Early and appropriate treatment of patients in intensive care unit (ICU) is critical when managing infections, which could help to reduce ...
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10
Serum Level Monitoring of Aminoglycoside Antibiotics
https://jamanetwork.com/journals/jamasurgery/fullarticle/590818
Serum aminoglycoside assays have been accepted as useful methods of enhancing therapeutic efficacy in the treatment of intensive care unit-acquired ...
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https://jamanetwork.com/journals/jamasurgery/fullarticle/590818
Serum aminoglycoside assays have been accepted as useful methods of enhancing therapeutic efficacy in the treatment of intensive care unit-acquired ...
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11
Full article: Appropriateness of empirical antibiotic therapy and ...
https://www.tandfonline.com/doi/full/10.1080/23744235.2021.1942543
In a prospective ICU trial, including 648 severe sepsis or septic shock patients (245 of them receiving gentamicin), short-course gentamicin therapy was not ...
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https://www.tandfonline.com/doi/full/10.1080/23744235.2021.1942543
In a prospective ICU trial, including 648 severe sepsis or septic shock patients (245 of them receiving gentamicin), short-course gentamicin therapy was not ...
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12
Treatment of sepsis in an intensive care unit | SpringerLink
https://link.springer.com/article/10.1007/BF01709709
Aminoglycoside/ureidopenicillin combinations are synergistic and widely used — often combined with metronidazole. Aminoglycoside toxicity can be reduced by ...
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https://link.springer.com/article/10.1007/BF01709709
Aminoglycoside/ureidopenicillin combinations are synergistic and widely used — often combined with metronidazole. Aminoglycoside toxicity can be reduced by ...
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13
An international survey on aminoglycoside practices in ...
https://hal.archives-ouvertes.fr/hal-03179747/document
Keywords: Antibiotics, Aminoglycoside, ICU, Therapeutic drug monitoring, PK/PD ... is a key issue for the optimal management of sepsis in.
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https://hal.archives-ouvertes.fr/hal-03179747/document
Keywords: Antibiotics, Aminoglycoside, ICU, Therapeutic drug monitoring, PK/PD ... is a key issue for the optimal management of sepsis in.
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14
Aminoglycosides in Critically Ill Septic Patients With Acute ...
https://www.sciencedirect.com/science/article/abs/pii/S0149291821002101
In conclusion, during IH, a significant number of ICU physicians still use a postdialysis schedule of aminoglycoside administration despite a predialysis ...
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https://www.sciencedirect.com/science/article/abs/pii/S0149291821002101
In conclusion, during IH, a significant number of ICU physicians still use a postdialysis schedule of aminoglycoside administration despite a predialysis ...
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15
Aminoglycosides in critically ill patients: which dosing ...
https://www.researchgate.net/publication/343343279_Aminoglycosides_in_critically_ill_patients_which_dosing_regimens_for_which_pathogens
Objectives: Low first-dose peak serum concentrations of amikacin and gentamicin are commonly reported in ICU patients. The present study aimed ...
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https://www.researchgate.net/publication/343343279_Aminoglycosides_in_critically_ill_patients_which_dosing_regimens_for_which_pathogens
Objectives: Low first-dose peak serum concentrations of amikacin and gentamicin are commonly reported in ICU patients. The present study aimed ...
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16
Prescription of Aminoglycosides in 23 French Neonatal Intensive ...
https://www.logipren.com/wp-content/uploads/2022/07/2021.11.21_Prescription-of-Aminoglycosides-in-23-French-Neonatal-Intensive-Care-units.pdf
2nd most prescribed drug in the neonatal intensive care unit (NICU). ... The end of an aminoglycoside treatment is defined by the cessation of the ...
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https://www.logipren.com/wp-content/uploads/2022/07/2021.11.21_Prescription-of-Aminoglycosides-in-23-French-Neonatal-Intensive-Care-units.pdf
2nd most prescribed drug in the neonatal intensive care unit (NICU). ... The end of an aminoglycoside treatment is defined by the cessation of the ...
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17
Pharmacokinetic dosing of aminoglycosides: a controlled trial
https://www.amjmed.com/article/S0002-9343(02)01476-6/abstract
Aminoglycosides have been a major component of antibiotic treatment of ... Aminoglycosides in the intensive care unit: an old drug in a dynamic environment.
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https://www.amjmed.com/article/S0002-9343(02)01476-6/abstract
Aminoglycosides have been a major component of antibiotic treatment of ... Aminoglycosides in the intensive care unit: an old drug in a dynamic environment.
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18
Medline ® Abstract for Reference 10 of 'Dosing ... - UpToDate
https://www.uptodate.com/contents/dosing-and-administration-of-parenteral-aminoglycosides/abstract/10
Aminoglycosides were used in different clinical settings (neonatal intensive care unit: 6 studies; cystic fibrosis: 3 studies; cancer: 5 studies; ...
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https://www.uptodate.com/contents/dosing-and-administration-of-parenteral-aminoglycosides/abstract/10
Aminoglycosides were used in different clinical settings (neonatal intensive care unit: 6 studies; cystic fibrosis: 3 studies; cancer: 5 studies; ...
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19
Aminoglycosides in the Intensive Care Unit - ProQuest
https://search.proquest.com/openview/a63dfdfabf1840e56e1c5652fef05992/1?pq-origsite=gscholar&cbl=2032437
Background: Although aminoglycosides are often used as treatment for Gram-negative infections, optimal dosing regimens remain unclear, especially in ICU ...
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https://search.proquest.com/openview/a63dfdfabf1840e56e1c5652fef05992/1?pq-origsite=gscholar&cbl=2032437
Background: Although aminoglycosides are often used as treatment for Gram-negative infections, optimal dosing regimens remain unclear, especially in ICU ...
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20
Isepamicin in intensive care unit patients with nosocomial ...
https://academic.oup.com/jac/article/44/1/99/750578
With respect to duration of treatment, nephrotoxicity is related to the length of aminoglycoside therapy, while these drugs are useful only during the first 5 ...
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https://academic.oup.com/jac/article/44/1/99/750578
With respect to duration of treatment, nephrotoxicity is related to the length of aminoglycoside therapy, while these drugs are useful only during the first 5 ...
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21
Short-course aminoglycosides as adjunctive empirical therapy ...
https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(20)30269-X/fulltext
Short-course adjunctive aminoglycoside treatment as part of ... It is unclear whether this strategy is beneficial in a non-ICU population.
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https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(20)30269-X/fulltext
Short-course adjunctive aminoglycoside treatment as part of ... It is unclear whether this strategy is beneficial in a non-ICU population.
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22
Impact of Aminoglycoside Cycling in Six Tertiary Intensive ...
https://www.bib.irb.hr/401232/download/401232.CroatMedJ_49_02071.pdf
intensive care units (ICU) on the rates of sepsis, aminoglycoside resis- ... otics, and the cost of antimicrobial treatment in ICUs. Methods. Setting.
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https://www.bib.irb.hr/401232/download/401232.CroatMedJ_49_02071.pdf
intensive care units (ICU) on the rates of sepsis, aminoglycoside resis- ... otics, and the cost of antimicrobial treatment in ICUs. Methods. Setting.
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23
Comment utiliser les aminosides en réanimation | Médecine ...
https://rea.revuesonline.com/articles/lvrea/ref/2015/05/lvrea243p328/lvrea243p328.html
Antimicrob Resist Infect Control 1:25 [CrossRef] [PubMed] [Google Scholar] ... Miller MA (2010) Management of aminoglycosides in the intensive care unit.
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https://rea.revuesonline.com/articles/lvrea/ref/2015/05/lvrea243p328/lvrea243p328.html
Antimicrob Resist Infect Control 1:25 [CrossRef] [PubMed] [Google Scholar] ... Miller MA (2010) Management of aminoglycosides in the intensive care unit.
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24
A systematic quantification of antibiotic interactions in E. coli ...
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00163-3/fulltext
Treatment of Blood Stream Infections (BSIs) with a combination of a β-lactam and an aminoglycoside antibiotic is widely used in intensive ...
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https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00163-3/fulltext
Treatment of Blood Stream Infections (BSIs) with a combination of a β-lactam and an aminoglycoside antibiotic is widely used in intensive ...
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25
Brasil - Investigation of carbapenemases and aminoglycoside ...
https://www.scielo.br/j/rsbmt/a/cGPmdNPLgf7TjNdYqwNvdbk/?lang=en
Aminoglycosides are a potential treatment option for CR A. baumannii infections ... patients from more than 100 cities in this region and has 117 ICU beds.
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https://www.scielo.br/j/rsbmt/a/cGPmdNPLgf7TjNdYqwNvdbk/?lang=en
Aminoglycosides are a potential treatment option for CR A. baumannii infections ... patients from more than 100 cities in this region and has 117 ICU beds.
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26
Aminoglycosides for the treatment of septic shock - Gale
https://go.gale.com/ps/i.do?id=GALE%7CA636887124&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=13648535&p=HRCA&sw=w
Aminoglycoside treatment was associated with worse outcomes, including increased requirements for renal replacement therapy during the ICU stay and higher ...
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https://go.gale.com/ps/i.do?id=GALE%7CA636887124&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=13648535&p=HRCA&sw=w
Aminoglycoside treatment was associated with worse outcomes, including increased requirements for renal replacement therapy during the ICU stay and higher ...
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27
1465: IMPACT OF ADJUNCTIVE AMINOGLYCOSIDES IN ...
https://journals.lww.com/ccmjournal/Fulltext/2022/01001/1465__IMPACT_OF_ADJUNCTIVE_AMINOGLYCOSIDES_IN.1431.aspx
Conclusions: The use of adjunctive AG therapy did not improve the time to resolution of hypotension in septic oncologic patients already receiving treatment ...
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https://journals.lww.com/ccmjournal/Fulltext/2022/01001/1465__IMPACT_OF_ADJUNCTIVE_AMINOGLYCOSIDES_IN.1431.aspx
Conclusions: The use of adjunctive AG therapy did not improve the time to resolution of hypotension in septic oncologic patients already receiving treatment ...
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28
Aminoglycosides: An Overview
http://perspectivesinmedicine.cshlp.org/content/6/6/a027029.full
Aminoglycosides are natural or semisynthetic antibiotics derived from ... isolated from patients hospitalized in intensive care units (ICUs) in the United ...
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http://perspectivesinmedicine.cshlp.org/content/6/6/a027029.full
Aminoglycosides are natural or semisynthetic antibiotics derived from ... isolated from patients hospitalized in intensive care units (ICUs) in the United ...
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29
PP197—Therapeutic Drug Monitoring of Vancomycin and ...
https://www.clinicaltherapeutics.com/article/S0149-2918(13)00610-3/fulltext
Therapeutic drug monitoring (TDM) is essential to optimize the use of antibiotics in intensive care units. Many TDM assessments may be inappropriate as a ...
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https://www.clinicaltherapeutics.com/article/S0149-2918(13)00610-3/fulltext
Therapeutic drug monitoring (TDM) is essential to optimize the use of antibiotics in intensive care units. Many TDM assessments may be inappropriate as a ...
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30
Aminoglycosides: Recommendations for use, dosing and ...
https://www.sahealth.sa.gov.au/wps/wcm/connect/public+content/sa+health+internet/resources/policies/aminoglycosides+recommendations+for+use+dosing+and+monitoring+clinical+guideline
Appendix 2 – Aminoglycosides for the treatment of infective endocarditis . ... The following National Safety and Quality Health Service ...
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https://www.sahealth.sa.gov.au/wps/wcm/connect/public+content/sa+health+internet/resources/policies/aminoglycosides+recommendations+for+use+dosing+and+monitoring+clinical+guideline
Appendix 2 – Aminoglycosides for the treatment of infective endocarditis . ... The following National Safety and Quality Health Service ...
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31
Aminoglycosides for the treatment of septic shock - Europe PMC
https://europepmc.org/article/med/32958018
Aminoglycoside treatment was associated with worse outcomes, including increased requirements for renal replacement therapy during the ICU stay ...
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https://europepmc.org/article/med/32958018
Aminoglycoside treatment was associated with worse outcomes, including increased requirements for renal replacement therapy during the ICU stay ...
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32
Infections in Patients in Intensive Care Units: Can the ... - jstor
https://www.jstor.org/stable/4456014
Serious infections encountered in the intensive care unit. (ICU) frequently necessitate ... tion consists of a f-lactam antibiotic and an aminoglycoside.
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https://www.jstor.org/stable/4456014
Serious infections encountered in the intensive care unit. (ICU) frequently necessitate ... tion consists of a f-lactam antibiotic and an aminoglycoside.
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33
Evaluation of aminoglycosides utilization ... - Pharmacy Practice
https://www.pharmacypractice.org/index.php/pp/article/view/1523
Conclusions: Non-adherence to the guidelines occurred frequently in the ICUs of Nemazee hospital. Prescription of loading dose, and AGs level ...
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https://www.pharmacypractice.org/index.php/pp/article/view/1523
Conclusions: Non-adherence to the guidelines occurred frequently in the ICUs of Nemazee hospital. Prescription of loading dose, and AGs level ...
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34
Stanford Health Care Aminoglycoside Dosing Guideline
https://med.stanford.edu/content/dam/sm/bugsanddrugs/documents/antimicrobial-dosing-protocols/SHC-Aminoglycoside-Dosing-Guide.pdf
Tradition dosing of aminoglycosides includes lower doses with more frequent administration of aminoglycosides using pharmacokinetic parameters to determine dose ...
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https://med.stanford.edu/content/dam/sm/bugsanddrugs/documents/antimicrobial-dosing-protocols/SHC-Aminoglycoside-Dosing-Guide.pdf
Tradition dosing of aminoglycosides includes lower doses with more frequent administration of aminoglycosides using pharmacokinetic parameters to determine dose ...
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35
Aminoglycosides: A Practical Review - AAFP
https://www.aafp.org/pubs/afp/issues/1998/1115/p1811.html
Aminoglycosides are used in the treatment of severe infections of the abdomen and urinary tract, as well as bacteremia and endocarditis.
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https://www.aafp.org/pubs/afp/issues/1998/1115/p1811.html
Aminoglycosides are used in the treatment of severe infections of the abdomen and urinary tract, as well as bacteremia and endocarditis.
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36
Aminoglycosides - Nursing CEs - CEUfast
https://ceufast.com/course/aminoglycosides
Intravenous administration of aminoglycosides should occur over at least 30 minutes for the traditional intermittent dosing strategy and at ...
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https://ceufast.com/course/aminoglycosides
Intravenous administration of aminoglycosides should occur over at least 30 minutes for the traditional intermittent dosing strategy and at ...
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37
Administration of Amino-glycoside in ICU Patients
https://clinicaltrials.gov/ct2/show/NCT02888470
In 2011, French guidelines on aminoglycoside use recommend a targeted Cmax of 30-40 mg/L for gentamicin and 60-80 mg/L for amikacin. However, ...
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https://clinicaltrials.gov/ct2/show/NCT02888470
In 2011, French guidelines on aminoglycoside use recommend a targeted Cmax of 30-40 mg/L for gentamicin and 60-80 mg/L for amikacin. However, ...
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38
An international survey on aminoglycoside practices in ...
https://d-nb.info/1232892300/34
Keywords: Antibiotics, Aminoglycoside, ICU, Therapeutic drug monitoring, PK/PD ... is a key issue for the optimal management of sepsis in.
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https://d-nb.info/1232892300/34
Keywords: Antibiotics, Aminoglycoside, ICU, Therapeutic drug monitoring, PK/PD ... is a key issue for the optimal management of sepsis in.
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39
Gentamicin Level: Reference Range, Collection and Panels ...
https://emedicine.medscape.com/article/2090086-overview
The use of gentamicin in the neonatal intensive care unit using a weight-based gentamicin dosing protocol should also account for serum ...
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https://emedicine.medscape.com/article/2090086-overview
The use of gentamicin in the neonatal intensive care unit using a weight-based gentamicin dosing protocol should also account for serum ...
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40
Aminoglycoside Dosing in Adults - Queensland Health
https://www.health.qld.gov.au/__data/assets/pdf_file/0019/713323/aminoglycoside-guidelines.pdf
7.3.2 In all other patients or for empirical treatment of endocarditis ........... 12 ... safety of high-dose gentamicin re-dosing in ICU patients receiving ...
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https://www.health.qld.gov.au/__data/assets/pdf_file/0019/713323/aminoglycoside-guidelines.pdf
7.3.2 In all other patients or for empirical treatment of endocarditis ........... 12 ... safety of high-dose gentamicin re-dosing in ICU patients receiving ...
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41
Dosing of Aminoglycosides in Chronic Kidney Disease and ...
https://www.karger.com/Article/FullText/523892
Nevertheless, since patients in intensive care units who are on CRRT therapy may be fluid-overloaded, the administration of relatively high doses (25 mg/kg ...
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https://www.karger.com/Article/FullText/523892
Nevertheless, since patients in intensive care units who are on CRRT therapy may be fluid-overloaded, the administration of relatively high doses (25 mg/kg ...
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42
Propensity-Based Study of Aminoglycoside Nephrotoxicity in ...
https://journals.asm.org/doi/10.1128/AAC.03750-14
In the ICU, AGs were always combined with β-lactams. Gentamicin (GEN) was recommended for treatment of infections due to Gram-positive or ...
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https://journals.asm.org/doi/10.1128/AAC.03750-14
In the ICU, AGs were always combined with β-lactams. Gentamicin (GEN) was recommended for treatment of infections due to Gram-positive or ...
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43
Aminoglycosides—alive and well in treatment of pediatric ...
https://jammi.utpjournals.press/doi/full/10.3138/jammi.2018.09.19
Since the 1980s, the use of aminoglycosides as a treatment for gram-negative sepsis has been supplanted mainly by cephalosporins and fluoroquinolones. A recent ...
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https://jammi.utpjournals.press/doi/full/10.3138/jammi.2018.09.19
Since the 1980s, the use of aminoglycosides as a treatment for gram-negative sepsis has been supplanted mainly by cephalosporins and fluoroquinolones. A recent ...
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44
Use of Aerosolized Aminoglycosides in the Treatment of Gram ...
https://www.liebertpub.com/doi/abs/10.1089/sur.2006.041
Conclusions: Ventilator-associated pneumonia in critically ill patients is associated with substantial morbidity, longer ICU stays, and ...
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https://www.liebertpub.com/doi/abs/10.1089/sur.2006.041
Conclusions: Ventilator-associated pneumonia in critically ill patients is associated with substantial morbidity, longer ICU stays, and ...
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45
Prevalence of Aminoglycoside Resistance and ...
https://www.dovepress.com/prevalence-of-aminoglycoside-resistance-and-aminoglycoside-modifying-e-peer-reviewed-fulltext-article-IDR
Aminoglycosides are commonly used in the treatment of A. baumannii health care-associated infections (HAIs). Aminoglycosides resistance ...
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https://www.dovepress.com/prevalence-of-aminoglycoside-resistance-and-aminoglycoside-modifying-e-peer-reviewed-fulltext-article-IDR
Aminoglycosides are commonly used in the treatment of A. baumannii health care-associated infections (HAIs). Aminoglycosides resistance ...
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46
The “Old” and the “New” Antibiotics for MDR Gram-Negative ...
https://www.frontiersin.org/articles/10.3389/fpubh.2019.00151/full
Aminoglycosides are still important companion antibiotics. Finally, fosfomycin as part of combination treatment for CRE infections and P.
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https://www.frontiersin.org/articles/10.3389/fpubh.2019.00151/full
Aminoglycosides are still important companion antibiotics. Finally, fosfomycin as part of combination treatment for CRE infections and P.
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47
IDSA Guidance on the Treatment of Antimicrobial-Resistant ...
https://www.idsociety.org/practice-guideline/amr-guidance/
A single intravenous dose is generally effective for cystitis, with minimal toxicity [28]. Individual aminoglycosides are equally effective if ...
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https://www.idsociety.org/practice-guideline/amr-guidance/
A single intravenous dose is generally effective for cystitis, with minimal toxicity [28]. Individual aminoglycosides are equally effective if ...
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48
Evaluation of Safety and Efficiency in Use of Aminoglycosides ...
https://www.scirp.org/journal/paperinformation.aspx?paperid=100428
Background: Aminoglycosides are used as empirical antibiotic treatment of intraabdominal infections which are caused by Gram negative bacteria and for which the ...
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https://www.scirp.org/journal/paperinformation.aspx?paperid=100428
Background: Aminoglycosides are used as empirical antibiotic treatment of intraabdominal infections which are caused by Gram negative bacteria and for which the ...
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49
Medicas UIS - SciELO Colombia
http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0121-03192016000200003
Aminoglycoside and quinolone resistance in strains of Klebsiella pneumonia isolated from two units of intensive care unit of the University of the Andes ...
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http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0121-03192016000200003
Aminoglycoside and quinolone resistance in strains of Klebsiella pneumonia isolated from two units of intensive care unit of the University of the Andes ...
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50
Gentamicin Article - StatPearls
https://www.statpearls.com/ArticleLibrary/viewarticle/22211
Serum gentamicin concentration monitoring is often unnecessary for a brief treatment duration (less than six days) in non-critical patients with ...
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https://www.statpearls.com/ArticleLibrary/viewarticle/22211
Serum gentamicin concentration monitoring is often unnecessary for a brief treatment duration (less than six days) in non-critical patients with ...
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51
Effect of using aminoglycosides for treatment of sepsis - FHI
https://www.fhi.no/globalassets/dokumenterfiler/rapporter/2015/rapport_2015_3_aminoglycosider.pdf
Norwegian Knowledge Centre for the Health Services summarizes and disseminates evidence concerning the effect of treatments, methods, and interventions in ...
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https://www.fhi.no/globalassets/dokumenterfiler/rapporter/2015/rapport_2015_3_aminoglycosider.pdf
Norwegian Knowledge Centre for the Health Services summarizes and disseminates evidence concerning the effect of treatments, methods, and interventions in ...
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52
The Effect of Aminoglycosides on Colistin-Containing ...
https://jag.journalagent.com/z4/download_fulltext.asp?pdir=erciyesmedj&un=EMJ-76093
Aminoglycosides on. Colistin-Containing. Regimens in the Treatment of Carbapenem-Resistant. Gram-Negative Infections in Pediatric Intensive. Care Units: A ...
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https://jag.journalagent.com/z4/download_fulltext.asp?pdir=erciyesmedj&un=EMJ-76093
Aminoglycosides on. Colistin-Containing. Regimens in the Treatment of Carbapenem-Resistant. Gram-Negative Infections in Pediatric Intensive. Care Units: A ...
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53
Pharmacokinetic and Pharmacodynamic Dose Optimization
https://www.uwhealth.org/cckm/cpg/infection-and-isolation/pkpd.pdf
Patients in the ICU, receiving antibiotics for treatment of septic shock, ... Empiric dosing of aminoglycosides occurs via three strategies: ...
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https://www.uwhealth.org/cckm/cpg/infection-and-isolation/pkpd.pdf
Patients in the ICU, receiving antibiotics for treatment of septic shock, ... Empiric dosing of aminoglycosides occurs via three strategies: ...
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54
Combination Therapy with Aminoglycoside in Bacteremiasdue ...
https://lilloa.univ-lille.fr/bitstream/handle/20.500.12210/40962/antibiotics-09-00777.pdf?sequence=1
Conclusions: In intensive care unit (ICU) patients with ESBL-E BSI, empirical treatment with aminoglycoside was frequent.
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https://lilloa.univ-lille.fr/bitstream/handle/20.500.12210/40962/antibiotics-09-00777.pdf?sequence=1
Conclusions: In intensive care unit (ICU) patients with ESBL-E BSI, empirical treatment with aminoglycoside was frequent.
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55
Extended-Interval Aminoglycoside Administration for Children
https://publications.aap.org/pediatrics/article/114/1/e111/64740/Extended-Interval-Aminoglycoside-Administration
Aminoglycosides were used in different clinical settings (neonatal intensive care unit: 6 studies; cystic fibrosis: 3 studies; ...
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https://publications.aap.org/pediatrics/article/114/1/e111/64740/Extended-Interval-Aminoglycoside-Administration
Aminoglycosides were used in different clinical settings (neonatal intensive care unit: 6 studies; cystic fibrosis: 3 studies; ...
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56
Evaluation of aminoglycosides utilization in intensive care ...
https://www.redalyc.org/journal/690/69061088010/
Objective: The aim of this study was to evaluate aminoglycosides (AGs) usage pattern at intensive care units (ICUs) of Nemazee hospital Shiraz, Iran.
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https://www.redalyc.org/journal/690/69061088010/
Objective: The aim of this study was to evaluate aminoglycosides (AGs) usage pattern at intensive care units (ICUs) of Nemazee hospital Shiraz, Iran.
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57
FULLTEXT01.pdf - https ://uu.diva-portal.org
http://uu.diva-portal.org/smash/get/diva2:1650745/FULLTEXT01.pdf
antibiotic is widely used in intensive care units (ICUs) around the world. However, no studies have ... tam combined with an aminoglycoside for treatment of.
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http://uu.diva-portal.org/smash/get/diva2:1650745/FULLTEXT01.pdf
antibiotic is widely used in intensive care units (ICUs) around the world. However, no studies have ... tam combined with an aminoglycoside for treatment of.
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58
Trends in Aminoglycoside Use and Gentamicin-Resistant ...
https://www.cambridge.org/core/journals/infection-control-and-hospital-epidemiology/article/trends-in-aminoglycoside-use-and-gentamicinresistant-gramnegative-clinical-isolates-in-us-academic-medical-centers-implications-for-antimicrobial-stewardship/5C69EF3D8453DE45E5D09EA69A1F312F
Antibiotic resistance among gram-negative bacilli in US intensive care units: implications for fluoroquinolone use. JAMA 2003;289: 885–888.
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https://www.cambridge.org/core/journals/infection-control-and-hospital-epidemiology/article/trends-in-aminoglycoside-use-and-gentamicinresistant-gramnegative-clinical-isolates-in-us-academic-medical-centers-implications-for-antimicrobial-stewardship/5C69EF3D8453DE45E5D09EA69A1F312F
Antibiotic resistance among gram-negative bacilli in US intensive care units: implications for fluoroquinolone use. JAMA 2003;289: 885–888.
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59
What is the Cost of Nephrotoxicity Associated with Aminoglycosides?
https://sci-hub.se/tree/89/f2/89f2c53dc93d7d2b65e8848894de220a.pdf
hospitalization; intensive care units; kidney failure, acute; ... ing aminoglycoside treatment or within 48 hours after the ter-.
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https://sci-hub.se/tree/89/f2/89f2c53dc93d7d2b65e8848894de220a.pdf
hospitalization; intensive care units; kidney failure, acute; ... ing aminoglycoside treatment or within 48 hours after the ter-.
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60
Tasty Morsels of Critical Care 024 | The aminoglycosides
https://emergencymedicineireland.com/tasty-morsels-of-critical-care-024-the-aminoglycosides/
In the ED and ICU the only aminoglycosides in town are gentamicin and its lesser used but much respected, big brother, amikacin.
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https://emergencymedicineireland.com/tasty-morsels-of-critical-care-024-the-aminoglycosides/
In the ED and ICU the only aminoglycosides in town are gentamicin and its lesser used but much respected, big brother, amikacin.
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61
Aminoglycoside Prescribing and Surveillance in Cystic Fibrosis
https://www.atsjournals.org/doi/full/10.1164/rccm.200109-012cc
However, if patients receive frequent (every 2 months) intravenous antibiotic treatment, clinicians may consider using alternate aminoglycoside ...
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https://www.atsjournals.org/doi/full/10.1164/rccm.200109-012cc
However, if patients receive frequent (every 2 months) intravenous antibiotic treatment, clinicians may consider using alternate aminoglycoside ...
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62
Antibiotics - EMCrit Project
https://emcrit.org/ibcc/antibiotics/
Community-acquired pneumonia or COPD in ICU: Front-loaded regimen with 500 mg IV daily for three days (long half-life in tissues so will have ...
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https://emcrit.org/ibcc/antibiotics/
Community-acquired pneumonia or COPD in ICU: Front-loaded regimen with 500 mg IV daily for three days (long half-life in tissues so will have ...
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63
Gentamicin is frequently underdosed in patients with sepsis in ...
http://www.njmonline.nl/getpdf.php?id=1644
treatment of sepsis in the emergency department. In our ... patients were more often directly admitted to the ICU (21%. Table 1.
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http://www.njmonline.nl/getpdf.php?id=1644
treatment of sepsis in the emergency department. In our ... patients were more often directly admitted to the ICU (21%. Table 1.
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64
Gentamicin: Uses, Interactions, Mechanism of Action - DrugBank
https://go.drugbank.com/drugs/DB00798
This synergistic activity is not only important for the treatment of complex ... is a good estimate of creatinine clearance in intensive care unit patients.
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https://go.drugbank.com/drugs/DB00798
This synergistic activity is not only important for the treatment of complex ... is a good estimate of creatinine clearance in intensive care unit patients.
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65
Aminoglycoside Dosing & Monitoring: Neonatal & Pediatric ...
https://www.med.unc.edu/pediatrics/cccp/wp-content/uploads/sites/1156/gravity_forms/1-c06e424ddddee8826f29e1bc5926a251/2022/04/Aminoglycoside-Dosing-and-Monitoring-Guideline-Pediatrics_2022_FINAL.pdf
When ordering levels for a patient in the Neonatal Critical Care Center (NCCC), ... preferred aminoglycoside in empiric neonatal sepsis management; however, ...
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https://www.med.unc.edu/pediatrics/cccp/wp-content/uploads/sites/1156/gravity_forms/1-c06e424ddddee8826f29e1bc5926a251/2022/04/Aminoglycoside-Dosing-and-Monitoring-Guideline-Pediatrics_2022_FINAL.pdf
When ordering levels for a patient in the Neonatal Critical Care Center (NCCC), ... preferred aminoglycoside in empiric neonatal sepsis management; however, ...
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66
Aminoglycoside Antibiotics - Testing.com
https://www.testing.com/tests/aminoglycoside-antibiotics/
The level of the prescribed aminoglycoside in the blood is measured in order to adjust doses as necessary and ensure effective treatment ...
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https://www.testing.com/tests/aminoglycoside-antibiotics/
The level of the prescribed aminoglycoside in the blood is measured in order to adjust doses as necessary and ensure effective treatment ...
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67
Nonpharmacologic Management of Acute Renal Injury - ClinicalKey
https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323449427000510#refInSitubib9
and approaching 70% for critically ill patients in the ICU. ... the use of aminoglycosides in the treatment of severe gram-negative infections in critically ...
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https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323449427000510#refInSitubib9
and approaching 70% for critically ill patients in the ICU. ... the use of aminoglycosides in the treatment of severe gram-negative infections in critically ...
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68
National Treatment Guidelines for Antimicrobial Use in ...
https://ncdc.gov.in/WriteReadData/l892s/File622.pdf
Treatment Of Muti-Drug Resistant Bacterial Pathogens. ... newborn and intensive care units. More than 50% of Escherichia ... aminoglycoside is used. Acute ...
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https://ncdc.gov.in/WriteReadData/l892s/File622.pdf
Treatment Of Muti-Drug Resistant Bacterial Pathogens. ... newborn and intensive care units. More than 50% of Escherichia ... aminoglycoside is used. Acute ...
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69
Procedure for Drawing Aminoglycoside Levels | LHSC
https://www.lhsc.on.ca/critical-care-trauma-centre/procedure-for-drawing-aminoglycoside-levels
... Critical Care Trauma Centre; Procedure for Drawing Aminoglycoside ... Drug Administration Time; Timing of Post Drug Level; Lab Ordering ...
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https://www.lhsc.on.ca/critical-care-trauma-centre/procedure-for-drawing-aminoglycoside-levels
... Critical Care Trauma Centre; Procedure for Drawing Aminoglycoside ... Drug Administration Time; Timing of Post Drug Level; Lab Ordering ...
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70
Aminoglycosides - Infectious Diseases - Merck Manuals
https://www.merckmanuals.com/professional/infectious-diseases/bacteria-and-antibacterial-drugs/aminoglycosides
Because treatment of enterococcal endocarditis requires prolonged use of a potentially nephrotoxic and ototoxic aminoglycoside plus a bacterial cell ...
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https://www.merckmanuals.com/professional/infectious-diseases/bacteria-and-antibacterial-drugs/aminoglycosides
Because treatment of enterococcal endocarditis requires prolonged use of a potentially nephrotoxic and ototoxic aminoglycoside plus a bacterial cell ...
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71
Aminoglycosides in gynecologic infections | Read by QxMD
https://read.qxmd.com/read/3728531/aminoglycosides-in-gynecologic-infections
Aminoglycosides have always had a major role in the treatment of gynecologic infections. ... How to improve intubation in the intensive care unit.
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https://read.qxmd.com/read/3728531/aminoglycosides-in-gynecologic-infections
Aminoglycosides have always had a major role in the treatment of gynecologic infections. ... How to improve intubation in the intensive care unit.
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72
Gentamicin - Wikipedia
https://en.wikipedia.org/wiki/Gentamicin
Gentamicin is an antibiotic used to treat several types of bacterial infections. This may include bone infections, endocarditis, pelvic inflammatory disease ...
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https://en.wikipedia.org/wiki/Gentamicin
Gentamicin is an antibiotic used to treat several types of bacterial infections. This may include bone infections, endocarditis, pelvic inflammatory disease ...
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73
Antibiotics - NHS
https://www.nhs.uk/conditions/antibiotics/
... long to clear without treatment; carry a risk of more serious complications ... Aminoglycosides (such as gentamicin and tobramycin) – tend to only be ...
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https://www.nhs.uk/conditions/antibiotics/
... long to clear without treatment; carry a risk of more serious complications ... Aminoglycosides (such as gentamicin and tobramycin) – tend to only be ...
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74
Aminoglycosides and how to dose them - YouTube
https://www.youtube.com/watch?v=aWzsopXMH_s
Aug 14, 2015
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https://www.youtube.com/watch?v=aWzsopXMH_s
Aug 14, 2015
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75
(PDF) Management of Antimicrobial Use in the Intensive Care Unit ...
https://www.academia.edu/50390705/Management_of_Antimicrobial_Use_in_the_Intensive_Care_Unit
Management of Antimicrobial Use in the Intensive Care Unit. ... 770 4.1 Extended-Interval Aminoglycoside Administration .
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https://www.academia.edu/50390705/Management_of_Antimicrobial_Use_in_the_Intensive_Care_Unit
Management of Antimicrobial Use in the Intensive Care Unit. ... 770 4.1 Extended-Interval Aminoglycoside Administration .
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76
3.12 Aminoglycosides – Nursing Pharmacology
https://wtcs.pressbooks.pub/pharmacology/chapter/3-12-aminoglycosides/
Special Administration Considerations: Aminoglycosides can result in many adverse effects for the patient and, therefore, the nurse should monitor the patient ...
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https://wtcs.pressbooks.pub/pharmacology/chapter/3-12-aminoglycosides/
Special Administration Considerations: Aminoglycosides can result in many adverse effects for the patient and, therefore, the nurse should monitor the patient ...
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77
PRIME PubMed | [Clinical epidemiology of an outbreak of ...
https://news.unboundmedicine.com/medline/citation/8429724/[Clinical_epidemiology_of_an_outbreak_of_nosocomial_infection_caused_by_Staphylococcus_aureus_resistant_to_methicillin_and_aminoglycosides:_efficacy_of_control_measures__Comit%C3%A9_de_Control_de_Infecciones]_
From the Intensive Care Units, the outbreak extended to the medical and surgical ... Despite the different control measures used, the MRSA infection has ...
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https://news.unboundmedicine.com/medline/citation/8429724/[Clinical_epidemiology_of_an_outbreak_of_nosocomial_infection_caused_by_Staphylococcus_aureus_resistant_to_methicillin_and_aminoglycosides:_efficacy_of_control_measures__Comit%C3%A9_de_Control_de_Infecciones]_
From the Intensive Care Units, the outbreak extended to the medical and surgical ... Despite the different control measures used, the MRSA infection has ...
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78
Aminoglycosides - Warnings, Precautions, Side Effects ...
https://www.everydayhealth.com/aminoglycosides/guide/
Because aminoglycosides are normally used to treat serious infections, they are typically administered into the veins of the body (intravenously ...
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https://www.everydayhealth.com/aminoglycosides/guide/
Because aminoglycosides are normally used to treat serious infections, they are typically administered into the veins of the body (intravenously ...
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79
Factsheet for the general public - Antimicrobial resistance
https://www.ecdc.europa.eu/en/antimicrobial-resistance/facts/factsheets/general-public
This may delay getting the right treatment to patients and may result in ... intensive care and other medical procedures would no longer be possible.
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https://www.ecdc.europa.eu/en/antimicrobial-resistance/facts/factsheets/general-public
This may delay getting the right treatment to patients and may result in ... intensive care and other medical procedures would no longer be possible.
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80
MedicinesComplete: Digital Medicines Information Suite
https://about.medicinescomplete.com/
Close. Login; Resources. Core; Agilio: Diagnosis and Treatment Guidance · BNF · BNF for Children · Critical Illness · Drug Monitoring Checker ...
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https://about.medicinescomplete.com/
Close. Login; Resources. Core; Agilio: Diagnosis and Treatment Guidance · BNF · BNF for Children · Critical Illness · Drug Monitoring Checker ...
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81
Treatment summaries A to Z | BNF - NICE
https://bnf.nice.org.uk/treatment-summaries/
A · Acne · Acute coronary syndromes · Acute porphyrias · Adrenal insufficiency · Age-related macular degeneration · Alcohol dependence · Aminoglycosides · Anaemia, iron ...
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https://bnf.nice.org.uk/treatment-summaries/
A · Acne · Acute coronary syndromes · Acute porphyrias · Adrenal insufficiency · Age-related macular degeneration · Alcohol dependence · Aminoglycosides · Anaemia, iron ...
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82
Clinical Pharmacokinetics of Aminoglycosides - SlidePlayer
https://slideplayer.com/slide/9465781/
AMG ANTIBIOTICS Widely used for the treatment of severe gram (-) infections such as pneumonia/bacteremia, often in combination with a β-lactam antibiotic.
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https://slideplayer.com/slide/9465781/
AMG ANTIBIOTICS Widely used for the treatment of severe gram (-) infections such as pneumonia/bacteremia, often in combination with a β-lactam antibiotic.
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83
Antibiotics - Aminoglycosides: Nursing Pharmacology - Osmosis
https://www.osmosis.org/learn/Antibiotics_-_Aminoglycosides:_Nursing_Pharmacology
Streptomycin and amikacin can be used in the treatment of mycobacterial infections. Gentamicin can also be applied topically to treat eye or ear infections; ...
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https://www.osmosis.org/learn/Antibiotics_-_Aminoglycosides:_Nursing_Pharmacology
Streptomycin and amikacin can be used in the treatment of mycobacterial infections. Gentamicin can also be applied topically to treat eye or ear infections; ...
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84
When monitoring for aminoglycoside toxicity, the nurse pays ...
https://biquyetxaynha.com/when-monitoring-for-aminoglycoside-toxicity-the-nurse-pays-special-attention-to-the
*Treatment of withdrawal (abstinence) from narcotics: ... Use of Intravenous Levetiracetam for Management of Acute Seizures in Neonates.
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https://biquyetxaynha.com/when-monitoring-for-aminoglycoside-toxicity-the-nurse-pays-special-attention-to-the
*Treatment of withdrawal (abstinence) from narcotics: ... Use of Intravenous Levetiracetam for Management of Acute Seizures in Neonates.
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85
Cumulated Index Medicus
https://books.google.com/books?id=MKxivLNug7IC&pg=PA2292&lpg=PA2292&dq=management+of+aminoglycosides+in+the+intensive+care+unit&source=bl&ots=ku8AA4_piB&sig=ACfU3U1IW60DEMQoxqi9vw2RNdLUIWI2MA&hl=en&sa=X&ved=2ahUKEwiKo-vuhMX7AhV7k2oFHahIBxoQ6AF6BQiwAhAD
( Antibiotic therapy in the intensive care unit ) Kohn R , et T , et al . ... intraocular ( Daily single - dose aminoglycoside administration . study .
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https://books.google.com/books?id=MKxivLNug7IC&pg=PA2292&lpg=PA2292&dq=management+of+aminoglycosides+in+the+intensive+care+unit&source=bl&ots=ku8AA4_piB&sig=ACfU3U1IW60DEMQoxqi9vw2RNdLUIWI2MA&hl=en&sa=X&ved=2ahUKEwiKo-vuhMX7AhV7k2oFHahIBxoQ6AF6BQiwAhAD
( Antibiotic therapy in the intensive care unit ) Kohn R , et T , et al . ... intraocular ( Daily single - dose aminoglycoside administration . study .
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86
Discovery of small molecules that target a tertiary-structured ...
https://www.pnas.org/doi/10.1073/pnas.2213117119
There were four copies of the complex in the asymmetric unit, ... The theophylline ligand is itself a commonly used drug for the treatment of asthma and ...
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https://www.pnas.org/doi/10.1073/pnas.2213117119
There were four copies of the complex in the asymmetric unit, ... The theophylline ligand is itself a commonly used drug for the treatment of asthma and ...
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87
Annotation of CPIC Guideline for amikacin, gentamicin ...
https://www.pharmgkb.org/guidelineAnnotation/PA166229081
Administration of aminoglycoside antibiotics should be avoided in patients carrying certain MT-RNR1 variants due to the increased risk of developing ...
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https://www.pharmgkb.org/guidelineAnnotation/PA166229081
Administration of aminoglycoside antibiotics should be avoided in patients carrying certain MT-RNR1 variants due to the increased risk of developing ...
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88
Infection Control in the Intensive Care Unit
https://books.google.com/books?id=Xq47SfclBcUC&pg=PA142&lpg=PA142&dq=management+of+aminoglycosides+in+the+intensive+care+unit&source=bl&ots=65Yeb3wnAN&sig=ACfU3U0BpGEx6a5D8yTUiUNsn30JKraTCw&hl=en&sa=X&ved=2ahUKEwiKo-vuhMX7AhV7k2oFHahIBxoQ6AF6BQjAAhAD
tiveness of kanamycin, gentamicin and tobramycin [110]. Amikacin is less vulnerable to these inactivating enzymes because of protective molecular side ...
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https://books.google.com/books?id=Xq47SfclBcUC&pg=PA142&lpg=PA142&dq=management+of+aminoglycosides+in+the+intensive+care+unit&source=bl&ots=65Yeb3wnAN&sig=ACfU3U0BpGEx6a5D8yTUiUNsn30JKraTCw&hl=en&sa=X&ved=2ahUKEwiKo-vuhMX7AhV7k2oFHahIBxoQ6AF6BQjAAhAD
tiveness of kanamycin, gentamicin and tobramycin [110]. Amikacin is less vulnerable to these inactivating enzymes because of protective molecular side ...
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89
Infections in the Adult Intensive Care Unit
https://books.google.com/books?id=-0p2R7Y6yksC&pg=PA63&lpg=PA63&dq=management+of+aminoglycosides+in+the+intensive+care+unit&source=bl&ots=TQRWqVgdh9&sig=ACfU3U1R3TjvhrufpCJv4yGqgZLVzrZu_Q&hl=en&sa=X&ved=2ahUKEwiKo-vuhMX7AhV7k2oFHahIBxoQ6AF6BQizAhAD
Continuous antibiotic administration mightbe beneficial when antibiotic activity ... Unlike many drugs used in ICU that are given per body weight or surface ...
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https://books.google.com/books?id=-0p2R7Y6yksC&pg=PA63&lpg=PA63&dq=management+of+aminoglycosides+in+the+intensive+care+unit&source=bl&ots=TQRWqVgdh9&sig=ACfU3U1R3TjvhrufpCJv4yGqgZLVzrZu_Q&hl=en&sa=X&ved=2ahUKEwiKo-vuhMX7AhV7k2oFHahIBxoQ6AF6BQizAhAD
Continuous antibiotic administration mightbe beneficial when antibiotic activity ... Unlike many drugs used in ICU that are given per body weight or surface ...
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90
Are antimicrobial agents that mimic the chemical structure of ...
https://hanghieugiatot.com/are-antimicrobial-agents-that-mimic-the-chemical-structure-of-dna-building-blocks
Once inside the cell, aminoglycosides bind to the 30S subunit of ribosomes ... during prolonged antibiotic treatment with ciprofloxacin (Fothergill et al., ...
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https://hanghieugiatot.com/are-antimicrobial-agents-that-mimic-the-chemical-structure-of-dna-building-blocks
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