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Google Keyword Rankings for : hsp90 central
1
Targeting the Hsp90-Cdc37-client protein interaction to disrupt ...
https://jhoonline.biomedcentral.com/articles/10.1186/s13045-018-0602-8
Hsp90 center dot Cdc37 complexes with protein kinases form cooperatively with multiple distinct interaction sites. J Biol Chem. 2015;290:30843– ...
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https://jhoonline.biomedcentral.com/articles/10.1186/s13045-018-0602-8
Hsp90 center dot Cdc37 complexes with protein kinases form cooperatively with multiple distinct interaction sites. J Biol Chem. 2015;290:30843– ...
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2
Network Analysis Identifies an HSP90-Central Hub ...
https://aacrjournals.org/clincancerres/article/19/18/5053/206095/Network-Analysis-Identifies-an-HSP90-Central-Hub
Network Analysis Identifies an HSP90-Central Hub Susceptible in Ovarian Cancer ... HSP90 is an ATP-dependent molecular chaperone protein that affects the ...
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https://aacrjournals.org/clincancerres/article/19/18/5053/206095/Network-Analysis-Identifies-an-HSP90-Central-Hub
Network Analysis Identifies an HSP90-Central Hub Susceptible in Ovarian Cancer ... HSP90 is an ATP-dependent molecular chaperone protein that affects the ...
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3
Structure, Function, and Regulation of the ... - CSH Perspectives
https://cshperspectives.cshlp.org/content/11/9/a034017.full
Because many Hsp90 clients represent central hubs of complex biological pathways, Hsp90 is a key factor of cellular regulation.
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https://cshperspectives.cshlp.org/content/11/9/a034017.full
Because many Hsp90 clients represent central hubs of complex biological pathways, Hsp90 is a key factor of cellular regulation.
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4
Development of a First-in-Class Small-Molecule Inhibitor of ...
https://pubs.acs.org/doi/10.1021/acscentsci.2c00013
In cancerous cells, Hsp90 expression is elevated,. ... of 5b onto the surface of Hsp90 (Figure 4a) revealed two main binding regions: one in ...
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https://pubs.acs.org/doi/10.1021/acscentsci.2c00013
In cancerous cells, Hsp90 expression is elevated,. ... of 5b onto the surface of Hsp90 (Figure 4a) revealed two main binding regions: one in ...
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5
A Central Role for the Hsp90·Cdc37 Molecular Chaperone ...
https://www.sciencedirect.com/science/article/pii/S0021925819303709
A Central Role for the Hsp90·Cdc37 Molecular Chaperone Module in Interleukin-1 Receptor-associated-kinase-dependent Signaling by Toll-like Receptors*.
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https://www.sciencedirect.com/science/article/pii/S0021925819303709
A Central Role for the Hsp90·Cdc37 Molecular Chaperone Module in Interleukin-1 Receptor-associated-kinase-dependent Signaling by Toll-like Receptors*.
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6
The role and therapeutic potential of Hsp90, Hsp70, and ...
https://onlinelibrary.wiley.com/doi/abs/10.1002/med.21729
As a consequence of both peripheral and central neuropathies, cellular stress occurs and results in the accumulation of unfolded and/or ...
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https://onlinelibrary.wiley.com/doi/abs/10.1002/med.21729
As a consequence of both peripheral and central neuropathies, cellular stress occurs and results in the accumulation of unfolded and/or ...
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7
Hsp90 : a specialized but essential protein-folding tool
https://rupress.org/jcb/article/154/2/267/32163/Hsp90-a-specialized-but-essential-protein-folding
Hsp90 is unique among molecular chaperones. ... Hsp90 is a constitutive homodimer with its main intersubunit contacts within the COOH-terminal 190 residues ...
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https://rupress.org/jcb/article/154/2/267/32163/Hsp90-a-specialized-but-essential-protein-folding
Hsp90 is unique among molecular chaperones. ... Hsp90 is a constitutive homodimer with its main intersubunit contacts within the COOH-terminal 190 residues ...
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8
HSP70 and HSP90 in Cancer: Cytosolic, Endoplasmic ...
https://www.frontiersin.org/articles/10.3389/fonc.2022.829520/full
HSP70 and HSP90 are two powerful chaperone machineries involved in survival ... HSP90α and HSP90β are the two main cytosolic HSP90 isoforms encoded by two ...
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https://www.frontiersin.org/articles/10.3389/fonc.2022.829520/full
HSP70 and HSP90 are two powerful chaperone machineries involved in survival ... HSP90α and HSP90β are the two main cytosolic HSP90 isoforms encoded by two ...
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9
Extended conformational states dominate the Hsp90 ...
https://www.jbc.org/article/S0021-9258(22)00542-7/pdf
The heat shock protein 90 (Hsp90) is a molecular chaperone central to client protein folding and maturation in eukaryotic.
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https://www.jbc.org/article/S0021-9258(22)00542-7/pdf
The heat shock protein 90 (Hsp90) is a molecular chaperone central to client protein folding and maturation in eukaryotic.
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10
Conformational dynamics modulate the catalytic activity of the ...
https://www.nature.com/articles/s41467-020-15050-0
The heat shock protein 90 (Hsp90) is an ATP-dependent molecular chaperone that controls protein maturation and folding, in addition to central ...
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https://www.nature.com/articles/s41467-020-15050-0
The heat shock protein 90 (Hsp90) is an ATP-dependent molecular chaperone that controls protein maturation and folding, in addition to central ...
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11
Activation of the ATPase Activity of Hsp90 by the ... - Cell Press
https://www.cell.com/molecular-cell/pdf/S1097-2765(02)00785-2.pdf
Client protein activation by Hsp90 involves a plethora of cochaperones whose ... TPR domain and to Hsp90 via its central and/or C-terminal TPR domain(s) (.
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https://www.cell.com/molecular-cell/pdf/S1097-2765(02)00785-2.pdf
Client protein activation by Hsp90 involves a plethora of cochaperones whose ... TPR domain and to Hsp90 via its central and/or C-terminal TPR domain(s) (.
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12
Structure, Function, and Regulation of the Hsp90 Machinery
https://baam.library.gwu.edu/discovery/fulldisplay?docid=cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6719599&context=PC&vid=01WRLC_GWA:live&lang=en&search_scope=DN_and_CI&adaptor=Primo%20Central&query=sub%2Cexact%2C%20Genes%2C%20Essential%20%2CAND&facet=citedby%2Cexact%2Ccdi_FETCH-LOGICAL-1499t-55cba35d38f831da8605aed0fe96381a993285d3afc9465e2033a509bf9d163c3&offset=0
... including protein kinases, transcription factors, and E3 ubiquitin ligases, positioning Hsp90 as a central regulator of cellular proteostasis.
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https://baam.library.gwu.edu/discovery/fulldisplay?docid=cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6719599&context=PC&vid=01WRLC_GWA:live&lang=en&search_scope=DN_and_CI&adaptor=Primo%20Central&query=sub%2Cexact%2C%20Genes%2C%20Essential%20%2CAND&facet=citedby%2Cexact%2Ccdi_FETCH-LOGICAL-1499t-55cba35d38f831da8605aed0fe96381a993285d3afc9465e2033a509bf9d163c3&offset=0
... including protein kinases, transcription factors, and E3 ubiquitin ligases, positioning Hsp90 as a central regulator of cellular proteostasis.
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13
The Role of Heat Shock Proteins in Regulating Receptor ...
https://molpharm.aspetjournals.org/content/95/5/468
The main proteins within the Hsp family, particularly Hsp70 and ... This also makes the Hsps, particularly Hsp90, central regulators of ...
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https://molpharm.aspetjournals.org/content/95/5/468
The main proteins within the Hsp family, particularly Hsp70 and ... This also makes the Hsps, particularly Hsp90, central regulators of ...
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14
Heat-shock Protein 90 (Hsp90) as a Molecular Target for ...
https://ar.iiarjournals.org/content/29/6/2031
Targeting Hsp90 for cancer therapy. Due to its central role in oncogenic signaling, Hsp90 provides an attractive target for the treatment of cancer. Inhibition ...
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https://ar.iiarjournals.org/content/29/6/2031
Targeting Hsp90 for cancer therapy. Due to its central role in oncogenic signaling, Hsp90 provides an attractive target for the treatment of cancer. Inhibition ...
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15
The high-affinity HSP90-CHIP complex recognizes and ...
https://cdr.lib.unc.edu/downloads/tt44pv070
CHIP is a critical regulator of the chaperone response and Hsp90 inhibi- tor–mediated p-tau degradation. We previously demonstrated that. CHIP is a central ...
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https://cdr.lib.unc.edu/downloads/tt44pv070
CHIP is a critical regulator of the chaperone response and Hsp90 inhibi- tor–mediated p-tau degradation. We previously demonstrated that. CHIP is a central ...
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16
Molecular Interaction Network of the Hsp90 Chaperone System
https://link.springer.com/chapter/10.1007/978-0-387-39975-1_3
Interaction networks emerging from these large scale efforts clearly demonstrate that Hsp90 plays a central role effecting multiple pathways and cellular ...
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https://link.springer.com/chapter/10.1007/978-0-387-39975-1_3
Interaction networks emerging from these large scale efforts clearly demonstrate that Hsp90 plays a central role effecting multiple pathways and cellular ...
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17
Hsp90 in Human Diseases: Molecular Mechanisms to ... - MDPI
https://www.mdpi.com/2073-4409/11/6/976/htm
Higher levels of chaperon Hsp90 has been found in a wide spectrum of cancers, suggesting a central role in the survival and growth of malignant cells [72,73 ...
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https://www.mdpi.com/2073-4409/11/6/976/htm
Higher levels of chaperon Hsp90 has been found in a wide spectrum of cancers, suggesting a central role in the survival and growth of malignant cells [72,73 ...
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18
6XG6: Full-length human mitochondrial Hsp90 ... - RCSB PDB
https://www.rcsb.org/structure/6XG6
Full-length human mitochondrial Hsp90 (TRAP1) with ADP-BeF3. ... PubMed: 32913054 Search on PubMedSearch on PubMed Central ...
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https://www.rcsb.org/structure/6XG6
Full-length human mitochondrial Hsp90 (TRAP1) with ADP-BeF3. ... PubMed: 32913054 Search on PubMedSearch on PubMed Central ...
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19
HSP90 functions in the circadian clock through stabilization of ...
https://www.pnas.org/doi/10.1073/pnas.1110406108
The molecular chaperone HSP90 is an abundant and central cellular element essential to the maturation and stabilization of numerous regulatory proteins ...
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https://www.pnas.org/doi/10.1073/pnas.1110406108
The molecular chaperone HSP90 is an abundant and central cellular element essential to the maturation and stabilization of numerous regulatory proteins ...
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20
HSP90AA1 - Heat shock protein HSP 90-alpha | UniProtKB
https://www.uniprot.org/uniprotkb/P07900/entry
HSP90 and its co-chaperones modulate transcription at least at three ... with the specific client and the central chaperone itself (PubMed:29127155).
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https://www.uniprot.org/uniprotkb/P07900/entry
HSP90 and its co-chaperones modulate transcription at least at three ... with the specific client and the central chaperone itself (PubMed:29127155).
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21
Network analysis identifies an HSP90-central ... - Europe PMC
https://europepmc.org/article/pmc/pmc3778161
Network analysis identifies an HSP90-central hub susceptible in ovarian cancer. ... Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, ...
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https://europepmc.org/article/pmc/pmc3778161
Network analysis identifies an HSP90-central hub susceptible in ovarian cancer. ... Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, ...
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22
Hsp90 - Wikipedia
https://en.wikipedia.org/wiki/Hsp90
Hsp90 (heat shock protein 90) is a chaperone protein that assists other proteins to fold ... Open main menu.
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https://en.wikipedia.org/wiki/Hsp90
Hsp90 (heat shock protein 90) is a chaperone protein that assists other proteins to fold ... Open main menu.
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23
Direct observation of Hsp90-induced compaction in a protein ...
https://www.biorxiv.org/content/10.1101/2021.08.08.455546v1
We conjecture that chain compaction may be central to how Hsp90 protects unstable kinases and receptor clients, regulates their activity, ...
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https://www.biorxiv.org/content/10.1101/2021.08.08.455546v1
We conjecture that chain compaction may be central to how Hsp90 protects unstable kinases and receptor clients, regulates their activity, ...
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24
HSP90 and its inhibitors (Review) - Spandidos Publications
https://www.spandidos-publications.com/10.3892/or_00000787/download
The HSP90 molecular chaperone family is highly conserved ... client proteins could be bound in the central cavity in this.
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https://www.spandidos-publications.com/10.3892/or_00000787/download
The HSP90 molecular chaperone family is highly conserved ... client proteins could be bound in the central cavity in this.
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25
Extracellular Hsp90 and protection of neuronal cells through ...
https://portlandpress.com/biochemsoctrans/article/49/5/2299/229620/Extracellular-Hsp90-and-protection-of-neuronal
Here, we review the properties of extracellular Hsp90 in cellular homeostasis in the heat shock response (HSR), focusing on cells of the central ...
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https://portlandpress.com/biochemsoctrans/article/49/5/2299/229620/Extracellular-Hsp90-and-protection-of-neuronal
Here, we review the properties of extracellular Hsp90 in cellular homeostasis in the heat shock response (HSR), focusing on cells of the central ...
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26
Hsp90 binds to the central region of REV1 ... - ResearchGate
https://www.researchgate.net/figure/Hsp90-binds-to-the-central-region-of-REV1-The-REV1-full-length-protein-1-1251-and_fig2_51235630
Download scientific diagram | Hsp90 binds to the central region of REV1. The REV1 full-length protein (1–1251) and various truncated mutants with an ...
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https://www.researchgate.net/figure/Hsp90-binds-to-the-central-region-of-REV1-The-REV1-full-length-protein-1-1251-and_fig2_51235630
Download scientific diagram | Hsp90 binds to the central region of REV1. The REV1 full-length protein (1–1251) and various truncated mutants with an ...
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27
molecular chaperone Hsp90 maintains Golgi organization and ...
https://academic.oup.com/jmcb/article/12/6/448/5575095
In Hsp90-depleted cells, however, the microtubules were compacted in the cell center and less dense in periphery, suggesting the compromised microtubule ...
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https://academic.oup.com/jmcb/article/12/6/448/5575095
In Hsp90-depleted cells, however, the microtubules were compacted in the cell center and less dense in periphery, suggesting the compromised microtubule ...
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28
Review Article Functions of the Hsp90 chaperone system
https://e-century.us/files/ijbmb/4/4/ijbmb1310007.pdf
Abstract: The molecular chaperone Hsp90 is an essential protein in eukaryotic organisms ... central role in human diseases like cancer, neu-.
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https://e-century.us/files/ijbmb/4/4/ijbmb1310007.pdf
Abstract: The molecular chaperone Hsp90 is an essential protein in eukaryotic organisms ... central role in human diseases like cancer, neu-.
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29
Hsp90 inhibition disrupts JAK-STAT signaling and leads to ...
https://www.haematologica.org/article/view/8338
Heat shock protein 90 (Hsp90) is an ATP-dependent protein chaperone ... Memorial Sloan Kettering Cancer Center's Institutional Review Board.
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https://www.haematologica.org/article/view/8338
Heat shock protein 90 (Hsp90) is an ATP-dependent protein chaperone ... Memorial Sloan Kettering Cancer Center's Institutional Review Board.
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30
Exploring the Functional Complementation between Grp94 ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166271
Grp94 and Hsp90 are the ER and cytoplasmic paralog members, ... yeast (kind gift from D. Bolon, University of Massachusetts Medical Center).
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166271
Grp94 and Hsp90 are the ER and cytoplasmic paralog members, ... yeast (kind gift from D. Bolon, University of Massachusetts Medical Center).
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31
Hsp90 Potentiates the Rapid Evolution of New Traits - Science
https://www.science.org/doi/pdf/10.1126/science.1118370?download=true
Hsp90 potentiated the evolution of drug resistance in a different way, by enabling new mutations to have ... anisms may be involved, Hsp90 plays a central.
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https://www.science.org/doi/pdf/10.1126/science.1118370?download=true
Hsp90 potentiated the evolution of drug resistance in a different way, by enabling new mutations to have ... anisms may be involved, Hsp90 plays a central.
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32
HSP90 at the hub of protein homeostasis - Lindquist Lab
http://lindquistlab.wi.mit.edu/PDFs/Taipale2010NRMCB.pdf
Abstract | Heat shock protein 90 (HSP90) is a highly conserved molecular chaperone ... identified two main classes of HSP90 clients: protein.
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http://lindquistlab.wi.mit.edu/PDFs/Taipale2010NRMCB.pdf
Abstract | Heat shock protein 90 (HSP90) is a highly conserved molecular chaperone ... identified two main classes of HSP90 clients: protein.
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33
Aha-type co-chaperones: the alpha or the omega of the Hsp90 ...
https://www.degruyter.com/document/doi/10.1515/hsz-2019-0341/html?lang=en
The activator of Hsp90 ATPase (Aha1), which is the main focus of this review, is a co-chaperone that can dramatically accelerate ATP hydrolysis ...
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https://www.degruyter.com/document/doi/10.1515/hsz-2019-0341/html?lang=en
The activator of Hsp90 ATPase (Aha1), which is the main focus of this review, is a co-chaperone that can dramatically accelerate ATP hydrolysis ...
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34
Targeted blockade of HSP90 impairs DNA-damage response ...
https://www.tandfonline.com/doi/full/10.1080/15384047.2019.1595279
Cell lines, culture conditions and antibodies. Identity verified OVCAR-3 and UWB 1.289 cells were obtained from the Fox Chase Cancer Center ( ...
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https://www.tandfonline.com/doi/full/10.1080/15384047.2019.1595279
Cell lines, culture conditions and antibodies. Identity verified OVCAR-3 and UWB 1.289 cells were obtained from the Fox Chase Cancer Center ( ...
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35
Hsp90 regulation of fibroblast activation in pulmonary fibrosis
https://insight.jci.org/articles/view/91454
Here, we found elevated Hsp90 staining in lung biopsies of patients with IPF. Notably, fibroblasts isolated from fibrotic lesions showed ...
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https://insight.jci.org/articles/view/91454
Here, we found elevated Hsp90 staining in lung biopsies of patients with IPF. Notably, fibroblasts isolated from fibrotic lesions showed ...
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36
HSP90: Enabler of Cancer Adaptation - Annual Reviews
https://www.annualreviews.org/doi/10.1146/annurev-cancerbio-030518-055533
The stability and function of many oncogenic mutant proteins depend on heat shock protein 90 (HSP90). This unique activity has inspired the exploration of ...
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https://www.annualreviews.org/doi/10.1146/annurev-cancerbio-030518-055533
The stability and function of many oncogenic mutant proteins depend on heat shock protein 90 (HSP90). This unique activity has inspired the exploration of ...
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37
The Hsp90 co-chaperone Sgt1 governs Candida albicans ...
https://scholars.duke.edu/display/pub792814
The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance. ... Pubmed Central ID. PMC3435277 ...
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https://scholars.duke.edu/display/pub792814
The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance. ... Pubmed Central ID. PMC3435277 ...
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38
Comprehensive fitness maps of Hsp90 show widespread ...
https://elifesciences.org/articles/53810
Hsp90 encodes a 709 amino acid protein and to our knowledge it is the ... which, due to Hsp90's central role in numerous cellular pathways, ...
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https://elifesciences.org/articles/53810
Hsp90 encodes a 709 amino acid protein and to our knowledge it is the ... which, due to Hsp90's central role in numerous cellular pathways, ...
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39
Leonard M. Neckers, Ph.D. - Center for Cancer Research
https://ccr.cancer.gov/staff-directory/leonard-m-neckers
Dr. Neckers identified the molecular chaperone Hsp90 as a key non-oncogene addiction of cancer, demonstrated that Hsp90 is an anticancer target, ...
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https://ccr.cancer.gov/staff-directory/leonard-m-neckers
Dr. Neckers identified the molecular chaperone Hsp90 as a key non-oncogene addiction of cancer, demonstrated that Hsp90 is an anticancer target, ...
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40
Efficacy of an HSP90 inhibitor, ganetespib, in preclinical ...
https://www.oncotarget.com/article/17180/text/
6Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA ... Keywords: HSP90 inhibitor, ganetespib, thyroid cancer.
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https://www.oncotarget.com/article/17180/text/
6Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA ... Keywords: HSP90 inhibitor, ganetespib, thyroid cancer.
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41
The Middle Domain of Hsp90 Acts as a Discriminator between ...
https://journals.asm.org/doi/10.1128/MCB.02188-05
A hallmark of the Hsp90 reaction cycle is binding and hydrolysis of ATP (20, 21, 26, 34). Although the catalytic center for this reaction has been identified ...
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https://journals.asm.org/doi/10.1128/MCB.02188-05
A hallmark of the Hsp90 reaction cycle is binding and hydrolysis of ATP (20, 21, 26, 34). Although the catalytic center for this reaction has been identified ...
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42
Hsp70 and Hsp90 are differentially expressed in crayfish ...
https://www.dovepress.com/hsp70-and-hsp90-are-differentially-expressed-in-crayfish-muscle-and-ne-peer-reviewed-fulltext-article-RRB
We found that Hsp70 and Hsp90 transcripts are upregulated under heat stress in both muscle and the central nervous system, but that their ...
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https://www.dovepress.com/hsp70-and-hsp90-are-differentially-expressed-in-crayfish-muscle-and-ne-peer-reviewed-fulltext-article-RRB
We found that Hsp70 and Hsp90 transcripts are upregulated under heat stress in both muscle and the central nervous system, but that their ...
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43
HSP90 beta Monoclonal Antibody (MBH90B) (MA1-10373)
https://www.thermofisher.com/antibody/product/HSP90-beta-Antibody-clone-MBH90B-Monoclonal/MA1-10373
Immunofluorescence analysis of HSP90 beta was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 ...
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https://www.thermofisher.com/antibody/product/HSP90-beta-Antibody-clone-MBH90B-Monoclonal/MA1-10373
Immunofluorescence analysis of HSP90 beta was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 ...
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44
Hsp90 Structure and Function in Cancer - SID
https://www.sid.ir/FileServer/JE/50003720180305.pdf
[PubMed Central: PMC4842758]. 34. Tsutsumi S, Neckers L. Extracellular heat shock protein 90: A role for a molecular chaperone in cell motility ...
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https://www.sid.ir/FileServer/JE/50003720180305.pdf
[PubMed Central: PMC4842758]. 34. Tsutsumi S, Neckers L. Extracellular heat shock protein 90: A role for a molecular chaperone in cell motility ...
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45
Human 90 kDa Heat Shock Protein Hsp90 as a Target for ...
https://benthamscience.com/article/38080
Hsp90 is a molecular chaperone involved in maintaining folding, stability and function of many proteins involved in apoptosis, signal-transduction pathways ...
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https://benthamscience.com/article/38080
Hsp90 is a molecular chaperone involved in maintaining folding, stability and function of many proteins involved in apoptosis, signal-transduction pathways ...
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46
J INTS BIO, M.D Anderson Cancer Center joint development
https://www.victoriaadvocate.com/j-ints-bio-m-d-anderson-cancer-center-joint-development---oral-hsp90-inhibitor/article_b112516d-321b-55f7-8203-c5d842793ed4.html
J INTS BIO, M.D Anderson Cancer Center joint development - oral HSP90 inhibitor 'JIN-001', presentation of preclinical assessment at 2022 SNO ...
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https://www.victoriaadvocate.com/j-ints-bio-m-d-anderson-cancer-center-joint-development---oral-hsp90-inhibitor/article_b112516d-321b-55f7-8203-c5d842793ed4.html
J INTS BIO, M.D Anderson Cancer Center joint development - oral HSP90 inhibitor 'JIN-001', presentation of preclinical assessment at 2022 SNO ...
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47
Hsp90 - YouTube
https://www.youtube.com/watch?v=WDWm90Nsx1Y
University of Rochester Biochemistry (Bio250)
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https://www.youtube.com/watch?v=WDWm90Nsx1Y
University of Rochester Biochemistry (Bio250)
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48
Hsp90, Human | 385898 - EMD Millipore
https://www.emdmillipore.com/PR/en/product/Hsp90-Human,EMD_BIO-385898
Hsp90, Human, is a ~90 kDa heat shock protein that is constitutively expressed and resides in the cytoplasm. It exists as a dimer and binds to several other ...
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https://www.emdmillipore.com/PR/en/product/Hsp90-Human,EMD_BIO-385898
Hsp90, Human, is a ~90 kDa heat shock protein that is constitutively expressed and resides in the cytoplasm. It exists as a dimer and binds to several other ...
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49
Heat Shock Protein 90 Inhibitors in Oncology | Bentham Science
https://www.eurekaselect.com/article/60119
Hsp90 inhibitors may be categorized into two main classes: natural and synthetic inhibitors. In this review, we will discuss the general properties and ...
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https://www.eurekaselect.com/article/60119
Hsp90 inhibitors may be categorized into two main classes: natural and synthetic inhibitors. In this review, we will discuss the general properties and ...
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50
Byrd Alzheimer's Center and Research Institute - USF Health
https://health.usf.edu/medicine/byrd
The USF Health Byrd Alzheimer's Center and Research Institute is dedicated ... between FKBP51 (a co-chaperone of HSP90) and its role in stress induced PTSD.
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https://health.usf.edu/medicine/byrd
The USF Health Byrd Alzheimer's Center and Research Institute is dedicated ... between FKBP51 (a co-chaperone of HSP90) and its role in stress induced PTSD.
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51
Protein Classes - HSP90 - UCL
https://www.ucl.ac.uk/~zcbtfi4/proteins.html
Some heat shock proteins, including this isoform are known to be antiapoptotic and are one of the main targets for cancer killing drugs. It helps by increasing ...
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https://www.ucl.ac.uk/~zcbtfi4/proteins.html
Some heat shock proteins, including this isoform are known to be antiapoptotic and are one of the main targets for cancer killing drugs. It helps by increasing ...
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52
Hsp90 Chaperone Machine (@Hsp90Machine) / Twitter
https://twitter.com/hsp90machine
Hsp90 conference in Leysin. ... 2022 ⌚️15:15 (UTC+1) (Afternoon schedule) Georgios Karras (UT MD Anderson Cancer Center, ) "Illuminating Hsp90's ...
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https://twitter.com/hsp90machine
Hsp90 conference in Leysin. ... 2022 ⌚️15:15 (UTC+1) (Afternoon schedule) Georgios Karras (UT MD Anderson Cancer Center, ) "Illuminating Hsp90's ...
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53
HSP90 Antibody#4874 - Cell Signaling Technology
https://www.cellsignal.com/products/primary-antibodies/hsp90-antibody/4874
HSP90 Antibody detects endogenous levels of total HSP90 protein, alpha and beta isoforms. This antibody does not cross-react with other HSPs. Species Reactivity ...
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https://www.cellsignal.com/products/primary-antibodies/hsp90-antibody/4874
HSP90 Antibody detects endogenous levels of total HSP90 protein, alpha and beta isoforms. This antibody does not cross-react with other HSPs. Species Reactivity ...
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54
Research | mollapourlab
https://www.mollapourlab.com/research
The Hsp90 clients participate in the full breadth of cellular processes, including cell growth and cell cycle control, signal transduction, DNA repair, ...
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https://www.mollapourlab.com/research
The Hsp90 clients participate in the full breadth of cellular processes, including cell growth and cell cycle control, signal transduction, DNA repair, ...
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55
Inhibitors of Molecular Chaperones as Therapeutic Agents
https://books.google.com/books?id=_nMoDwAAQBAJ&pg=PA11&lpg=PA11&dq=hsp90+central&source=bl&ots=joiGNGI-K2&sig=ACfU3U1iieFGZ3_MFhZ4gnp7BV5sG_cunQ&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiJAhAD
Therefore, designing competitive inhibitors that target the N-terminal ATP binding pocket of Hsp90 has been the main strategy to block Hsp90.53 The ...
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https://books.google.com/books?id=_nMoDwAAQBAJ&pg=PA11&lpg=PA11&dq=hsp90+central&source=bl&ots=joiGNGI-K2&sig=ACfU3U1iieFGZ3_MFhZ4gnp7BV5sG_cunQ&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiJAhAD
Therefore, designing competitive inhibitors that target the N-terminal ATP binding pocket of Hsp90 has been the main strategy to block Hsp90.53 The ...
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56
Media Announcements | News Room | ATSDR - gov.cdc.wwwn
https://wwwn.cdc.gov/TSP/NEWS/NewsLanding.aspx
› TSP › NEWS › NewsLanding
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https://wwwn.cdc.gov/TSP/NEWS/NewsLanding.aspx
› TSP › NEWS › NewsLanding
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57
BondbloX and TransFICC sign MOU to enhance connectivity ...
https://www.yahoo.com/now/bondblox-transficc-sign-mou-enhance-131000995.html
As an exchange, settlement is atomic, prices are fully transparent, and execution is on a Central-Limit-Order Book.
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https://www.yahoo.com/now/bondblox-transficc-sign-mou-enhance-131000995.html
As an exchange, settlement is atomic, prices are fully transparent, and execution is on a Central-Limit-Order Book.
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58
Heat Shock Proteins in Inflammatory Diseases
https://books.google.com/books?id=dwtIEAAAQBAJ&pg=PA182&lpg=PA182&dq=hsp90+central&source=bl&ots=cQRVrEh4-Z&sig=ACfU3U3VovbEoYvIcW81p0JSMRpiCVf42w&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiPAhAD
HSP90 further activates MMP-9 to promote cell invasion. ... HSP70 has a central role in HSP response and this protein Table 1 HSP90 associated cancers HSP90 ...
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https://books.google.com/books?id=dwtIEAAAQBAJ&pg=PA182&lpg=PA182&dq=hsp90+central&source=bl&ots=cQRVrEh4-Z&sig=ACfU3U3VovbEoYvIcW81p0JSMRpiCVf42w&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiPAhAD
HSP90 further activates MMP-9 to promote cell invasion. ... HSP70 has a central role in HSP response and this protein Table 1 HSP90 associated cancers HSP90 ...
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59
Handbook of Neurochemistry and Molecular Neurobiology: Acute ...
https://books.google.com/books?id=9TWFEAAAQBAJ&pg=PA95&lpg=PA95&dq=hsp90+central&source=bl&ots=hdXokOBoJn&sig=ACfU3U1h14rotgMbecKXGwhn3ZNSRwSkNw&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiMAhAD
Hsp90 is one of the most abundant proteins in unstressed cells (1%–2% of ... domain of Hsp70 and a central TPR domain of Hsp90, with Hsp90 functioning as a ...
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https://books.google.com/books?id=9TWFEAAAQBAJ&pg=PA95&lpg=PA95&dq=hsp90+central&source=bl&ots=hdXokOBoJn&sig=ACfU3U1h14rotgMbecKXGwhn3ZNSRwSkNw&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiMAhAD
Hsp90 is one of the most abundant proteins in unstressed cells (1%–2% of ... domain of Hsp70 and a central TPR domain of Hsp90, with Hsp90 functioning as a ...
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60
Heat Shock Proteins in Human Diseases
https://books.google.com/books?id=soMlEAAAQBAJ&pg=PA187&lpg=PA187&dq=hsp90+central&source=bl&ots=-xjSJZBX6t&sig=ACfU3U06DLn-JsQHBpfGhIf018-j-dw1Dw&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiNAhAD
Given the central role of Hsp90 in viral polymerase function, and the targeting of DNA polymerase by anti-KSHV agents, it would be interesting to confirm ...
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https://books.google.com/books?id=soMlEAAAQBAJ&pg=PA187&lpg=PA187&dq=hsp90+central&source=bl&ots=-xjSJZBX6t&sig=ACfU3U06DLn-JsQHBpfGhIf018-j-dw1Dw&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiNAhAD
Given the central role of Hsp90 in viral polymerase function, and the targeting of DNA polymerase by anti-KSHV agents, it would be interesting to confirm ...
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61
Hsp90 in Cancer: Beyond the Usual Suspects
https://books.google.com/books?id=owHSBgAAQBAJ&pg=PA108&lpg=PA108&dq=hsp90+central&source=bl&ots=H3w_EWffw8&sig=ACfU3U1ZQRsAlJgw5-FEUjDhUOaQyrkU9g&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiRAhAD
events is discussed within the framework of Hsp90's capacity to enable ... and supports processes central to cancer progression (Chae et al., 2013).
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https://books.google.com/books?id=owHSBgAAQBAJ&pg=PA108&lpg=PA108&dq=hsp90+central&source=bl&ots=H3w_EWffw8&sig=ACfU3U1ZQRsAlJgw5-FEUjDhUOaQyrkU9g&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiRAhAD
events is discussed within the framework of Hsp90's capacity to enable ... and supports processes central to cancer progression (Chae et al., 2013).
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62
Alzheimer's and Parkinson's Diseases
https://books.google.com/books?id=uTYXXbdROOwC&pg=PA114&lpg=PA114&dq=hsp90+central&source=bl&ots=XayY3oRFU-&sig=ACfU3U0hfilbkdsrrKP1_xrrIurVPoOlow&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiOAhAD
338 The High-Affinity Hsp90-Chip Complex Recognizes and Selectively Degrades ... a central role for the Hsp90 complex in the pathogenesis of tauopathies.
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https://books.google.com/books?id=uTYXXbdROOwC&pg=PA114&lpg=PA114&dq=hsp90+central&source=bl&ots=XayY3oRFU-&sig=ACfU3U0hfilbkdsrrKP1_xrrIurVPoOlow&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiOAhAD
338 The High-Affinity Hsp90-Chip Complex Recognizes and Selectively Degrades ... a central role for the Hsp90 complex in the pathogenesis of tauopathies.
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63
Stem Cell Biology in Neoplasms of the Central Nervous System
https://books.google.com/books?id=eZxwCAAAQBAJ&pg=PA173&lpg=PA173&dq=hsp90+central&source=bl&ots=iH7GIXk7EV&sig=ACfU3U02sXu7LczpyklJI-dFl6oDZmxx4Q&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiQAhAD
A molecular chaperone, 90-kDa heat-shock protein (hsp90), has recently been described as a chemotherapy sensitizer because it is expressed at 2–10-fold ...
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https://books.google.com/books?id=eZxwCAAAQBAJ&pg=PA173&lpg=PA173&dq=hsp90+central&source=bl&ots=iH7GIXk7EV&sig=ACfU3U02sXu7LczpyklJI-dFl6oDZmxx4Q&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiQAhAD
A molecular chaperone, 90-kDa heat-shock protein (hsp90), has recently been described as a chemotherapy sensitizer because it is expressed at 2–10-fold ...
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64
Hsp90 - EMF-Portal
https://www.emf-portal.org/en/glossary/3496
Hsp90. German: Hsp90. Japanese: Hsp90 · Biochemistry. A heat shock protein with the molecular mass of 90 kDa that is one of the most abundant proteins in ...
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https://www.emf-portal.org/en/glossary/3496
Hsp90. German: Hsp90. Japanese: Hsp90 · Biochemistry. A heat shock protein with the molecular mass of 90 kDa that is one of the most abundant proteins in ...
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65
Molecular dynamics github - J-Shop
https://j-shop.fr/molecular-dynamics-github.html
... [31] (the successor to ptraj) is the main program in Amber for processing ... as applied to the N-terminal domain of Hsp90 (heat shock protein 90).
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https://j-shop.fr/molecular-dynamics-github.html
... [31] (the successor to ptraj) is the main program in Amber for processing ... as applied to the N-terminal domain of Hsp90 (heat shock protein 90).
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66
Proteins—Advances in Research and Application: 2012 Edition
https://books.google.com/books?id=s7ZK-_zioB4C&pg=PA1169&lpg=PA1169&dq=hsp90+central&source=bl&ots=tbui6z0bUV&sig=ACfU3U0u6EI7AOYO6acF1Io08augHM6c_g&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQj8ARAD
Current study results from the report, “Molecular chaperone Hsp90 regulates ... Japan, “REV1 is a Yfamily polymerase that plays a central role in mutagenic ...
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https://books.google.com/books?id=s7ZK-_zioB4C&pg=PA1169&lpg=PA1169&dq=hsp90+central&source=bl&ots=tbui6z0bUV&sig=ACfU3U0u6EI7AOYO6acF1Io08augHM6c_g&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQj8ARAD
Current study results from the report, “Molecular chaperone Hsp90 regulates ... Japan, “REV1 is a Yfamily polymerase that plays a central role in mutagenic ...
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67
Protein Folding Disorders Of The Central Nervous System
https://books.google.com/books?id=dJA4DwAAQBAJ&pg=PA149&lpg=PA149&dq=hsp90+central&source=bl&ots=6ghK8NXt7q&sig=ACfU3U3OUSJeFu2hl1H9-qWGJQnC_5YUaw&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiHAhAD
Moreover, chaperone Hsp90 regulates tau stabilization and it was shown that Hsp90 inhibition led to tau clearance [85, 174].
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https://books.google.com/books?id=dJA4DwAAQBAJ&pg=PA149&lpg=PA149&dq=hsp90+central&source=bl&ots=6ghK8NXt7q&sig=ACfU3U3OUSJeFu2hl1H9-qWGJQnC_5YUaw&hl=en&sa=X&ved=2ahUKEwjY2OWwoMX7AhVN_rsIHX2gBdAQ6AF6BQiHAhAD
Moreover, chaperone Hsp90 regulates tau stabilization and it was shown that Hsp90 inhibition led to tau clearance [85, 174].
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68
Wee1 activation. ( a) MCF-7 cells were treated with MK-1775 ...
http://rubyredquilting.com/vaohmlo/wee1-activation.html
Wee1 protein kinase consists of three domains: N-terminal domain, central ... blocks These data demonstrate that combined inhibition of Wee1 and Hsp90 ...
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http://rubyredquilting.com/vaohmlo/wee1-activation.html
Wee1 protein kinase consists of three domains: N-terminal domain, central ... blocks These data demonstrate that combined inhibition of Wee1 and Hsp90 ...
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69
Zaburzenia immunologiczne w liszaju płaskim - Dermatologia
https://www.termedia.pl/dermatologia/Zaburzenia-immunologiczne-w-liszaju-plaskim,49445.html
Stopień wybarwienia anty-Hsp90 wzrósł jedynie w błonie podstawnej dziąseł i podniebienia. Stężenie Hsp70 uległo natomiast zmniejszeniu [24].
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https://www.termedia.pl/dermatologia/Zaburzenia-immunologiczne-w-liszaju-plaskim,49445.html
Stopień wybarwienia anty-Hsp90 wzrósł jedynie w błonie podstawnej dziąseł i podniebienia. Stężenie Hsp70 uległo natomiast zmniejszeniu [24].
→ Check Latest Keyword Rankings ←
70
international journal of molecular sciences q1
https://dcinstituto.com.br/75gc7/international-journal-of-molecular-sciences-q1
... it expresses how central to the global scientific discussion an average ... Hsp70, Hsp90, Hsp104, and their related and subfields that ranks journals by ...
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https://dcinstituto.com.br/75gc7/international-journal-of-molecular-sciences-q1
... it expresses how central to the global scientific discussion an average ... Hsp70, Hsp90, Hsp104, and their related and subfields that ranks journals by ...
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71
โปรตีนช็อกความร้อน การค้นพบและฟังก์ชัน
https://hmong.in.th/wiki/Heat_shock_protein
โปรตีนช็อกจากความร้อนมีบทบาทสำคัญต่อหัวใจและหลอดเลือด Hsp90, ... "A central role for HSC70 in regulating antigen trafficking and MHC class II presentation".
→ Check Latest Keyword Rankings ←
https://hmong.in.th/wiki/Heat_shock_protein
โปรตีนช็อกจากความร้อนมีบทบาทสำคัญต่อหัวใจและหลอดเลือด Hsp90, ... "A central role for HSC70 in regulating antigen trafficking and MHC class II presentation".
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72
Hsp90 - Wikiwand
https://www.wikiwand.com/en/Hsp90
Hsp90 is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation.
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https://www.wikiwand.com/en/Hsp90
Hsp90 is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation.
→ Check Latest Keyword Rankings ←
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