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1 Mechanisms by which amniotic-fluid alpha-fetoprotein may be ...
https://pubmed.ncbi.nlm.nih.gov/60574/
It is concluded that elevated AFP in the amniotic fluid is a reliable but nonspecific marker for open neural tube defects prior to the 26th week of pregnancy, ...
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2 Alpha-Fetoprotein (AFP) Test: MedlinePlus Medical Test
https://medlineplus.gov/lab-tests/alpha-fetoprotein-afp-test/
An AFP blood test is used during pregnancy to check the baby's risk of birth defects and genetic disorders, such as neural tube defects or ...
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3 Neural Tube Defects in the Neonatal Period Workup
https://emedicine.medscape.com/article/1825866-workup
The presence of open neural tube defects (NTDs) can be detected with the measurement of alpha-fetoprotein (AFP) in the amniotic fluid or ...
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4 Alpha-Fetoprotein (Blood) - Health Encyclopedia
https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=alpha_fetoprotein_maternal_blood
Amniotic fluid is the liquid that surrounds your baby during pregnancy. When a developing baby has an open neural tube defect, it often causes a high level of ...
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5 Elevated Alpha-Fetoprotein - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/medicine-and-dentistry/elevated-alpha-fetoprotein
Although used to screen for neural tube defects, AFP is also elevated in such defects as omphalocele, gastroschisis, and sacrococcygeal teratoma, ...
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6 Alpha-Fetoprotein (AFP), Single Marker Screen, Maternal ...
https://bassett.testcatalog.org/show/LAB692-1
Measurement of maternal serum AFP values is a standard tool used in obstetrical care to identify pregnancies that may have an increased risk for NTD. The screen ...
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7 AFP Blood Test During Pregnancy - WebMD
https://www.webmd.com/baby/afp-blood-test-pregnancy
A negative or normal test usually means your baby likely does not have genetic abnormalities related to the neural tube. A positive test with a ...
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8 AFP Plus Quad Test - Women & Infants Hospital
https://www.womenandinfants.org/services/medical-screening/afp-plus-quad-test
The level of AFP alone is used to determine whether there is an increased likelihood of having a pregnancy with an open neural tube defect. Women with a raised ...
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9 Neural Tube Defect Screening - Penn Medicine
https://www.pennmedicine.org/for-patients-and-visitors/find-a-program-or-service/obstetrics/prenatal-genetic-testing/diagnosis-and-screening-services/neural-tube-defect-screening
Measuring the alpha-fetoprotein (AFP) level by a blood test checks for open NTDs. About 80 percent of the time when a woman is carrying a child with spina ...
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10 What is Spina Bifida?
https://spinabifidakentucky.org/about-spina-bifida/what-is-spina-bifida.html
However, when an open neural tube defect is present, the amniotic fluid contains an elevated amount of AFP because the skin surrounding the baby's spine is gone ...
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11 The Second Trimester: What to Know | MUSC Health
https://muschealth.org/medical-services/womens/pregnancy/second-trimester
AFP screening can detect pregnancies with open neural tube defects because these defects allow greater than normal amounts of AFP to cross into the mother's ...
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12 Alphafetoprotein and neural tube defects
https://jcp.bmj.com/content/jclinpath/s3-10/1/157.full.pdf
The neural tube defects (NTD) are a groupof con- ... Table II Elevated amniotic fluid AFP concentrations associated with other defects.
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13 Alpha-Fetoprotein Test (AFP) - American Pregnancy Association
https://americanpregnancy.org/prenatal-testing/alpha-fetoprotein-test/
High levels of AFP may suggest the developing baby has a neural tube defect such as spina bifida or anencephaly. High levels of AFP may also suggest defects ...
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14 Alpha Fetoprotein - Prenatal Genetics
https://www.gbmc.org/alphafetoprotein
Causes of elevated AFP are: ... Neural Tube Defects: Neural tube defects include both spina bifida (improper closure of the fetal spine) and anencephaly (improper ...
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15 Alpha-fetoprotein (AFP) Screening Test
https://www.stanfordchildrens.org/en/topic/default?id=alpha-fetoprotein-afp-90-P02426
Open neural tube defects (ONTD), such as spina bifida · Down syndrome · Other chromosomal abnormalities · Defects in the abdominal wall of the baby · Twins (more ...
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16 Alpha-fetoprotein (AFP) — new aspects of a well
https://journals.viamedica.pl/ginekologia_polska/article/download/GP.a2021.0226/65078
Such leakage does not occur in the case of closed neural tube defects, because the CSF is not washed into the amniotic fluid. Elevated AFP.
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17 EXPERIENCE WITH α-FETOPROTEIN (AFP) IN PRENATAL ...
https://www.nature.com/articles/pr1974438
In the overall total of 577 cases, 43 were mothers who had previously had an affected child with a NTD. No elevated AFP levels were found in ...
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18 AFP Testing for Improved Pregnancy Outcome - Maryland.gov
https://health.maryland.gov/phpa/genetics/pages/afp_tst.aspx
Maternal serum AFP testing is not perfect. It is only a screening test and can miss a few neural tube defects. However, it offers the best means available for ...
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19 Prenatal screening for open neural tube defects: This new ...
https://www.gimjournal.org/article/S1098-3600(21)03731-X/fulltext
Prenatal testing for ONTDs by measurement of alpha-fetoprotein (AFP) is considered a screening test when performed in maternal serum and a diagnostic test ...
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20 Neural tube defects: Overview of prenatal screening ...
https://www.uptodate.com/contents/open-neural-tube-defects-risk-factors-prenatal-screening-and-diagnosis-and-pregnancy-management
Neural tube defects (NTDs) are relatively common congenital anomalies that develop when a portion of the neural tube fails to close normally ...
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21 Maternal Serum Triple Analyte Screening in Pregnancy - AAFP
https://www.aafp.org/pubs/afp/issues/2002/0301/p915.html
Measurement of AFP alone can detect the vast majority of neural tube defects and a small portion of trisomy 21–affected pregnancies in ...
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22 Midtrimester screening for open neural tube defects
https://www.ajronline.org/doi/pdf/10.2214/ajr.149.1.141
fluid AFP level of 3.86 multiples of the mean. All were positive for AChE. Three cases of open spina bifida were correctly diagnosed by sonography. The ...
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23 MATERNAL SERUM ALPHA-FETOPROTEIN ... - Atrium Health
https://atriumhealth.org/documents/charlotteobgyn/charlotte-ob-gyn-msafp-test.pdf
Higher than normal levels of AFP indicate that unborn baby may have a neural tube defect but there are other causes for having an elevated level.
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24 Alpha-Fetoprotein (AFP) Test: Procedure and Results
https://my.clevelandclinic.org/health/diagnostics/24301-alpha-fetoprotein-test
Genetic disorders, such as Down syndrome or Turner syndrome. · Incorrect due dates. · Multiples, such as twins or triplets. · Neural tube defects, ...
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25 Maternal Alpha-Fetoprotein (AFP), and its Significance
https://labpedia.net/maternal-alpha-fetoprotein-afp-and-its-significance/
This is an effective screening marker for diagnosing body wall defects in the fetus, like neural tube defect, spina bifida, or anencephaly. · AFP ...
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26 Maternal Serum Alpha-Fetoprotein (MSAFP)
https://www.highmarkblueshield.com/preg/000206.html
Unusually high AFP levels are associated with an increased risk of a neural tube defect such as spina bifida or anencephaly, ...
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27 Alpha-fetoprotein (AFP) - Obstetrics - Medbullets Step 2/3
https://step2.medbullets.com/obstetrics/120354/alpha-fetoprotein-afp
Her alpha-fetoprotein (AFP) level was found to be decreased. ... assesses for neural tube defects or genetic conditions.
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28 Evaluation of sensitivity and accuracy of maternal serum alpha ...
https://ejrnm.springeropen.com/articles/10.1186/s43055-022-00855-4
NTD is one of the most important problems of the nervous system and the second ... have a higher diagnostic value than the AFP laboratory level.
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29 Alpha-Fetoprotein - Obstetrics and Gynecology
https://obgyn.onlinelibrary.wiley.com/doi/pdf/10.1016/0020-7292%2882%2990138-2
abnormalities. An elevated maternal serum AFP. (MSAFP) level identifies the fetus with an increased risk of neural tube defects or ventral wall defect, ...
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30 Serum alpha feto-protein screening in high risk pregnancies
https://link.springer.com/article/10.1007/BF02752193
Serum AFP levels were elevated in the presence of neural tube defect (NTD) and gut atresia in fetus, twin pregnancies, preterm delivery and neonatal ...
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31 Maternal serum alpha-feto protein : screening test
https://archives.lib.state.ma.us/bitstream/handle/2452/845864/ocm31363821.pdf?sequence=1&isAllowed=y
neural tube defects in the fetus. It is also used as a screening test for Down Syndrome. MSAFP Triple Test (also known as AFP Profile or AFP.
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32 Maternal Serum Alpha-Fetoprotein Screening and the Role of ...
https://journals.sagepub.com/doi/pdf/10.1177/875647939000600602
and decreased levels of MS-AFP. Elevated MS-AFP levels have been associated with inaccurate dates, fetal demise, neural tube defects, abdominal wall defects ...
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33 AFP assesses risk of fetal neural tube defects and Down ...
http://www.clinlabnavigator.com/alpha-fetoprotein-maternal-serum-msafp.html
Alpha fetoprotein or AFP in maternal blood is used in prenatal testing to assess risk of Down Syndrome and neural tube defects in a fetus.
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34 Alpha-fetoprotein (AFP) - Patient.info
https://patient.info/doctor/alpha-fetoprotein
Maternal serum AFP test results, interpreted according to the gestational age. See also the articles on Prenatal Diagnosis and Neural Tube ...
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35 Neural tube defects | Antenatal and Neonatal Screening
https://academic.oup.com/book/343/chapter/134995228
The timing of screening is a compromise. The AFP test is usually part of the triple or quadruple screening test for Down's syndrome (see Chapter 4) which, if ...
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36 Maternal Serum AFP - Quest Diagnostics
https://www.questdiagnostics.com/healthcare-professionals/clinical-education-center/faq/faq74v1
Elevated AFP screen results have been associated with pregnancy complications including fetal ventral wall defects (VWD) and other fetal anomalies, low birth ...
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37 Amniotic Fluid Alpha-fetoprotein (AF-AFP) and ... - GeneDx
https://www.genedx.com/Resources/TIS-Files/TIS-2122-1952-1.pdf
If there is a higher level of AFP than expected in the amniotic fluid, an opening in the spinal column (neural tube defect or NTD) may be present. AF-. AFP may ...
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38 Neural Tube Defects (NTDs) - PerkinElmer
https://rh.perkinelmer.com/disorders/neural-tube-defects-ntds/
Amniotic fluid tests: testing amniotic fluid may also show a high level of AFP, as well as high levels of acetylcholinesterase. Health care providers might ...
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39 Maternal Serum Screen, Alpha Fetoprotein
https://ltd.aruplab.com/Tests/Pub/3000144
Second-trimester screening test for open neural tube defects. Order this test for PREGNANT FEMALE patients only. ... 0080918, MoM for AFP, 20450-3.
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40 α-Fetoprotein (AFP), Maternal Serum for Open Spina Bifida
https://www.labcorp.com/tests/010801/fetoprotein-afp-maternal-serum-for-open-spina-bifida
Screening test for open neural tube defects. Detects 80% of open spina bifida and 90% of anencephaly. Please note that this test does not provide screening ...
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41 5 Ways to Lower the Risk of Having a Pregnancy Affected by a ...
https://www.cdc.gov/ncbddd/birthdefects/5-ways-to-lower-the-risk.html
Neural tube defects occur early during pregnancy and happen when the neural tube, which forms the brain ... A genetic test may have told you that you have a ...
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42 Patient Brochure for Alpha-Fetoprotein (AFP) Testing
https://www.accessdata.fda.gov/cdrh_docs/pdf/P010007d.pdf
If you are thinking of having the AFP blood test, you should be aware that the test itself is not a guarantee. It possible that a neural tube defect may be ...
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43 Fetal Neural Tube Defects: Diagnosis, Management ... - GLOWM
https://www.glowm.com/section-view/heading/Fetal%20Neural%20Tube%20Defects:%20Diagnosis,%20Management,%20and%20Treatment/item/224
Amniocentesis is often used to differentiate the disorders responsible for a maternal serum AFP elevation. If there is an amniotic fluid AFP elevation, a ...
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44 Spina bifida - Diagnosis and treatment - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/spina-bifida/diagnosis-treatment/drc-20377865
For the MSAFP test, a sample of the mother's blood is drawn and ... high levels of AFP suggest that the baby has a neural tube defect, ...
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45 Understanding the Triple Test - Sonora Quest Laboratories
https://www.sonoraquest.com/patient/knowledge-center/understanding-the-triple-test/
MSAFP (Maternal serum AFP) may lead to the detection of up to 85% of open neural tube defects when used in conjunction with diagnostic procedures such as ...
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46 Alpha-Fetoprotein (Blood) - Spectrum Health Lakeland
https://www.spectrumhealthlakeland.org/population-health/health-library/Content/167/alpha_fetoprotein_maternal_blood/
Higher levels of AFP may mean that your fetus has an abnormality such as a neural tube defect. An example is spina bifida. Neural tube defects are serious ...
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47 Prenatal Screening for Fetal Defects
https://www.aacc.org/-/media/Files/Meetings-and-Events/Resources-from-Past-Events/Conferences/2013/Professional-Practice/April-29/PNT_Prenatal_Screening_Apr_29_2013.pdf?la
markers are used to screen for open neural tube defects and determine aneuploidy risk ... Test Name. ONTD. DS. T18. Trimester. AFP Only.
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48 Routine measurement of amniotic fluid alpha-fetoprotein and ...
https://www.ajog.org/article/S0002-9378(14)00122-7/abstract
Those with an elevated AF-AFP were compared with those whose AF-AFP was within ... Levels of AF-AFP correlate with the likelihood of an NTD, ...
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49 Information About The Alpha-Fetoprotein Test
https://walnuthillobgyn.com/blog/alpha-fetoprotein-test/
When the amniotic fluid level of AFP is elevated and all other causes have been ruled out, it is very likely that the fetus has a neural tube defect.
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50 Alpha-Fetoprotein Test: Purpose, Procedure, and Results
https://www.healthline.com/health/alpha-fetoprotein
If you're pregnant you have higher-than-normal AFP levels, it can indicate a neural tube defect in your developing baby. However, the most common cause of ...
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51 New Abbott Test Can Help Doctors Detect the Presence of ...
https://abbott.mediaroom.com/2013-03-28-New-Abbott-Test-Can-Help-Doctors-Detect-the-Presence-of-Two-Important-Health-Issues
When the neural tube, a structure that develops into the brain and spinal cord, fails to close properly, AFP is thought to leak directly from ...
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52 Routine assessment of amniotic fluid alpha-Fetoprotein in ...
https://www.tandfonline.com/doi/full/10.1080/00016340601048012
Open fetal neural tube defects are often followed by an increase in ... When an elevated AF-AFP concentration was revealed, repeated targeted ...
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53 Alpha-Fetoprotein, Amniotic Fluid (AFPA) - Marshfield Labs
https://www.marshfieldlabs.org/sites/ltrm/Human/Pages/23214.aspx
Increases in alpha-fetoprotein (AFP) are not specific for neural tube defects, and the test must be used in combination with other procedures such as ...
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54 Alpha-Fetoprotein (AFP) Test - Kaiser Permanente
https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.alpha-fetoprotein-afp-test.hw1663
The age (gestational age) of the baby is wrong. · The woman is pregnant with more than one baby, such as twins or triplets. · The baby has a neural tube defect.
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55 First-Trimester Screening for Neural Tube Defects Using ...
https://fetalmedicine.org/fmf/1409201204.pdf
is reduced, whereas in neural tube defects AFP is in- creased [1, 2] . ... pregnancies the maternal serum level of AFP is reduced.
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56 Elevated Maternal Serum AFP (MSAFP) During the Second ...
https://www.exxcellence.org/pearls-of-exxcellence/list-of-pearls/elevated-maternal-serum-afp-msafp-during-the-second-trimester/
MSAFP is often elevated when there is an open fetal defect such as spina bifida, anencephaly, or an abdominal wall defect. The median MSAFP is ...
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57 Lab Test: Alpha 1-Fetoprotein (AFP; Blood) - EBM Consult
https://www.ebmconsult.com/articles/lab-test-alpha-1-fetoprotein-afp
While a positive maternal serum AFP result is not diagnostic for NTD it warrants further evaluation to include acetylcholinesterase measurement of amniotic ...
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58 What Is An AFP Test And How To Interpret The Test Result?
https://teslascans.com/what-is-an-afp-test/
Spina bifida- Also known as neural tube defect. · Down Syndrome- A chromosomal abnormality causing a developmental delay. · Error in determining the due date, ...
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59 First-Trimester Screening for Neural Tube ... - Karger Publishers
https://www.karger.com/Article/Abstract/335677
The detection rates of NTD in screening by serum AFP were 50.0% (95% ... in maternal blood as a screening test for fetal neural-tube defect.
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60 What is the Alpha Fetoprotein Test? - News Medical
https://www.news-medical.net/health/What-is-the-Alpha-Fetoprotein-Test.aspx
AFP passes from the fetal circulation into the fetal kidneys to be excreted into the amniotic fluid. Open defects of the neural tube cause excessive amounts ...
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61 Neural Tube Defects: Screening and Prevention
https://arup.utah.edu/media/neural_tube/NTD_Moser_04-09_final.pdf
defects. – Describe current prenatal screening for neural tube defects. – Explain the impact of folic acid ... Some recommend to re-test AFP (if <3.0.
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62 Elevated levels of amniotic fluid alpha-fetoprotein
https://pubs.rsna.org/doi/10.1148/radiology.188.1.7685529
All cases of AF-AFP elevation among 22,355 genetic amniocenteses were represented. Sonography correctly showed 32 open neural-tube defects, ...
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63 Alpha-fetoprotein (AFP) tests in pregnancy - MyDr.com.au
https://www.mydr.com.au/tests-investigations/alpha-fetoprotein-afp-tests-in-pregnancy/
What do abnormal AFP test results mean? · neural tube defects (problems with the spine, such as spina bifida); · defects in the wall of the ...
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64 Medical Definition of Alpha-fetoprotein (AFP) - RxList
https://www.rxlist.com/alpha-fetoprotein_afp/definition.htm
Open neural tube defects (anencephaly and spina bifida); and; Down syndrome (and other chromosome abnormalities). The maternal serum AFP (MSAFP) tends to be:.
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65 Maternal Serum AFP - Quest Joint DOS
https://jdos.nicholsinstitute.com/dos/coxhealth/test/380199
Prenatal risk assessment for open neural tube defects (NTDs). For manual orders use “Maternal Serum Screen Requisition." The MSAFP test in pregnant women ...
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66 Alpha-fetoprotein (AFP) Screening Test - Health Library
http://johnshopkinshealthcare.staywellsolutionsonline.com/Library/DiseasesConditions/Pediatric/HighRiskPregnancy/90,P02426
Open neural tube defects, such as spina bifida. Down syndrome. Other chromosomal abnormalities. Defects in the abdominal wall of the baby. Twins (more than 1 ...
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67 Alpha Fetoprotein Article - StatPearls
https://www.statpearls.com/ArticleLibrary/viewarticle/17402
Pregnant maternal serum AFP levels elevated: Neural tube defects (e.g., spina bifida, anencephaly); Omphalocele; Gastroschisis.
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68 Alpha Fetoprotein (AFP) - Beaumont Health
https://www.beaumont.org/treatments/alpha-fetoprotein
Alpha-fetoprotein (AFP) screening is a blood test that measures the AFP level in ... open neural tube defects (ONTD), such as spina bifida; Down syndrome ...
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69 Alpha-Fetoprotein (Amniotic Fluid) - Mount Nittany Health
https://mountnittany.org/wellness-article/alphafetoprotein-amniotic-fluid
Ask your healthcare provider what your test results mean for you. High levels of both AFP and AChE mean your fetus may have an open neural tube defect.
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70 Elevated alpha-fetoprotein - Wikipedia
https://en.wikipedia.org/wiki/Elevated_alpha-fetoprotein
normal elevation. 75% of AF AFP test results in the range 2.0 to 4.9 MoM are false positives: the baby is normal. · open neural tube defect · open abdominal wall ...
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71 False positivity of prenatal Down's syndrome and neural-tube ...
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)72892-0/fulltext
Abnormal maternal serum AFP concentrations with no increase in neural-tube or other birth defects have been associated with higher prednisone ...
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72 Alpha-Fetoprotein (AFP) Test – Health Information Library
https://www.peacehealth.org/medical-topics/id/hw1663
The age (gestational age) of the baby is wrong. · The woman is pregnant with more than one baby, such as twins or triplets. · The baby has a neural tube defect.
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73 Alpha-fetoprotein (AFP) - Children's Hospital of Philadelphia
https://www.chop.edu/conditions-diseases/alpha-fetoprotein-afp
The AFP blood test is called MSAFP (maternal serum AFP). The AFP can also be ... Open neural tube defects (ONTD), such as spina bifida. Down syndrome.
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74 Point-of-Care Quantification of Serum Alpha-Fetoprotein for ...
https://biomedeng.jmir.org/2021/1/e23527
The AFP test on the mobile platform can be applied to enable screening for ... Neural tube defects (NTDs) are one of the most common and ...
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75 Alpha-Fetoprotein (Blood) | Saint Luke's Health System
https://www.saintlukeskc.org/health-library/alpha-fetoprotein-blood
Higher levels of AFP may mean that your fetus has an abnormality, such as a neural tube defect or Down syndrome. Neural tube defects are serious birth ...
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76 Alpha-fetoprotein Screen - Maternal Serum Testing - GenPath
https://www.genpathdiagnostics.com/hcp/womens-health/prenatal-screening/maternal-serum-screening/alpha-fetoprotein/
The Alpha-fetoprotein (AFP) Screen is a second trimester screen that assesses the risk of a baby being born with open neural tube defects (ONTDs) by measuring ...
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77 Korean Journal of Obstetrics & Gynecology
https://ogscience.org/m/makeCookie.php?url=/m/journal/view.php?number=4646
For prenatal diagnosis of open neural tube defects [ONTDs] in pregnant women by ... RESULTS: Sixty one cases [5.4%, 61/1,137] had elevated level of AF AFP ...
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78 The clinical significance of human alpha-fetoprotein
http://www.annclinlabsci.org/content/8/2/84.full.pdf
Emphasis is given to the usefulness of elevated serum AFP ... The ability to detect neural tube defects early in gesta tion by monitoring maternal serum and ...
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79 AFP (Alpha-Fetoprotein) Screen - Ask Dr Sears
https://www.askdrsears.com/topics/pregnancy-childbirth/first-month/afp-alpha-feto-protein-screen/
Maternal levels of AFP are elevated if the mother is carrying a baby with a neural tube defect, NTD, (the vertebrae that normally enclose ...
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80 Maternal Serum AFP Tetra Profile: | Obstetrics and ...
https://www.obgynofhampton.com/afp/
... test can estimate her risk of having a baby with open neural tube defects, ... AFP Tetra is a screening test that measures four proteins in a pregnant ...
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81 Alpha-fetoprotein (AFP) Screening Test - UCI Health
https://www.ucihealth.org/health-library/content?contentTypeID=90&contentID=P02426
What is an alpha-fetoprotein (AFP) screening test? · Open neural tube defects, such as spina bifida · Down syndrome · Other chromosomal abnormalities · Defects in ...
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82 ALPHA-FETOPROTEIN, Maternal Serum - Test Details
https://www.utmb.edu/lsg2/Home/Details?id=484
: 7 mL of blood in SST (gold top) tube or red stoppered tube. When screening for neural tube defect and Down Syndrome, a 'Patient Information Form for AFP ...
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83 Alpha-fetoprotein (AFP) Screening Test - University Hospitals
https://www.uhhospitals.org/health-information/health-and-wellness-library/article/pediatric-diseases-and-conditions-v0/alpha-fetoprotein-afp
Open neural tube defects, such as spina bifida · Down syndrome · Other chromosomal abnormalities · Defects in the abdominal wall of the baby · Twins (more than 1 ...
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84 Relevance of biochemical parameters in the prenatal ...
https://www.degruyter.com/document/doi/10.1515/9783110850307-018/pdf
an elevation of AFP level in the amniotic fluid. In the fetal spinal fluid, high levels of AFP are detectable. The presence of open neural tube defects ...
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85 Screening for Open Neural Tube Defects
https://www.labmed.theclinics.com/article/S0272-2712(10)00042-9/pdf
the advent of alpha-fetoprotein (AFP) screening for neural tube defects.1,2 It was from ... AFP test during the second trimester of pregnancy.
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86 Alpha-fetoprotein (AFP) Screening Test
https://www.nationwidechildrens.org/conditions/health-library/alpha-fetoprotein-afp-screening-test
Open neural tube defects, such as spina bifida · Down syndrome · Other chromosomal abnormalities · Defects in the abdominal wall of the baby · Twins (more than 1 ...
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87 Screening for Neural Tube Defects as a Model
https://biotech.law.lsu.edu/map/ScreeningforNeuralTubeDefectsasaModel.html
Neural tube defects are common, occurring in 1 or 2 per 1000 births among ... The woman with an elevated amnionic AFP but no identifiable defect has the ...
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88 Alpha-fetoprotein Values in Maternal Serum and Amniotic ...
https://synapse.koreamed.org/func/download.php?path=L2hvbWUvdmlydHVhbC9rYW1qZS9zeW5hcHNlL3VwbG9hZC9TeW5hcHNlRGF0YS9QREZEYXRhLzAwNjl5bWoveW1qLTI4LTIxOC5wZGY=&filename=eW1qLTI4LTIxOC5wZGY=
the fetus including neural tube defect and aneuploid fetus. This study was undertaken to determine the ... B. Maternal serum and amniotic fluid AFP level.
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89 Pregnant Women with High Maternal Serum–Alpha-Fetoprotein
https://radiologykey.com/pregnant-women-with-high-maternal-serum-alpha-fetoprotein/
Alpha-fetoprotein (AFP) screening was shown to be effective for detecting neural tube defects (NTDs) in the 1970s.1In 1991, the American ...
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90 Alpha-Fetoprotein (AFP) Blood Test - MedicineNet
https://www.medicinenet.com/alpha-fetoprotein_blood_test/article.htm
A neural tube defect is an abnormal fetal brain or spinal cord that is caused by folic acid deficiency during pregnancy. Examples of these birth defects include ...
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91 Elevated Maternal Serum Alpha-Fetoprotein (MSAFP) -
https://www.carnegieimaging.com/blog/elevated-maternal-serum-alpha-fetoprotein-msafp-2/
Elevated MSAFP is associated with structural fetal anomalies, including neural tube defects, abdominal wall defects, and duodenal atresia.
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92 Prenatal Detection of Neural Tube Defects - JAMA Network
https://jamanetwork.com/journals/jama/fullarticle/372999
Pregnancy was electively terminated in 11 cases in which the AFP concentration was thought to be elevated but in which the fetus was apparently ...
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93 PRIME PubMed | Amniotic fluid alpha-fetoprotein levels and the ...
https://neuro.unboundmedicine.com/medline/citation/79418/Amniotic_fluid_alpha_fetoprotein_levels_and_the_prenatal_diagnosis_of_neural_tube_defects:_a_collaborative_study_of_2180_pregnancies_in_the_Netherlands_
In 12 patients investigated before 20 weeks gestation, pregnancy was terminated because of a raised amniotic fluid AFP-level: 11 fetuses had neural tube defects ...
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94 Iowa Registry for Congenital and Inherited Disorders, IRCID
https://ircid.public-health.uiowa.edu/risk.html
A protein called alphafetoprotein (AFP) is made in the fetal liver. When a fetus has an open neural tube defect, this protein leaks through the defect and ...
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95 Alpha Fetoprotein (AFP) Quad Screen, Penta Screen, Test ...
https://www.lonetreeobgyn.com/contents/obstetrics/alpha-fetoprotein
Clinical Use. Prenatal risk assessment for neural tube defects (NTDs), Down syndrome, and trisomy 18. Clinical Background. Prenatal screening is routinely ...
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96 Alpha-Fetoprotein (AFP) Test
https://www.cham.org/HealthwiseArticle.aspx?id=hw1663
Why It Is Done · Check the developing baby (fetus) of a pregnant woman for brain or spinal problems (called neural tube defects). · Check the developing baby ( ...
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