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1 Current treatment of atypical hemolytic uremic syndrome - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204535/
Dosing schedules and laboratory monitoring: Eculizumab is administered as an intravenous infusion. The recommended dosing for adult patients with aHUS is 900 mg ...
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2 Atypical Hemolytic Uremic Syndrome (aHUS): Treating the ...
https://www.hematologyandoncology.net/supplements/atypical-hemolytic-uremic-syndrome-ahus-treating-the-patient/
Patients who present with clinical and laboratory evidence of a TMA should begin immediate treatment with plasma therapy, but there is no role for plasma ...
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3 aHUS | Alexion
https://alexion.com/our-medicines/conditions-we-treat/ahus
An update for atypical haemolytic uraemic syndrome: diagnosis and treatment. A consensus document. Nefrologia. 2015;35(5):421-447. Krishnappa V, Gupta M, ...
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4 Soliris: Infusion Therapy for aHUS
https://infusionassociates.com/infusion-therapy/soliris-for-ahus/
aHus patients can be treated with an infusion medication called Soliris. Infusion therapy involves inserting an IV line into a vein in your arm to ...
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5 Atypical Hemolytic Uremic Syndrome
https://rarediseases.org/rare-diseases/atypical-hemolytic-uremic-syndrome/
In 2011, the U.S Food and Drug Administration (FDA) approved the use of the humanized anti-C5 monoclonal antibody eculizumab as a treatment for acute hemolytic ...
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6 aHUS (atypical hemolytic uremic syndrome)
https://www.kidneyfund.org/all-about-kidneys/other-kidney-diseases/ahus-atypical-hemolytic-uremic-syndrome
Doctors may treat aHUS with: · aHUS affects everyone differently. · Because aHUS is a genetic disease, there is no known way to prevent it. · aHUS ...
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7 Decision Process: Discontinuing aHUS Treatment
https://www.ahusallianceaction.org/decision-process-discontinuing-ahus-treatment/
As noted in a 2019 article by Yadav et al, “Plasma exchange (PEX) remains the standard therapy for the management of atypical hemolytic-uremic ...
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8 Hemolytic-Uremic Syndrome Treatment & Management
https://emedicine.medscape.com/article/201181-treatment
The US Food and Drug Administration has approved two monoclonal antibodies for the treatment of hemolytic-uremic syndrome (HUS) that is not ...
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9 For atypical-HUS - ULTOMIRIS (ravulizumab-cwvz)
https://ultomiris.com/ahus
adults and children 1 month of age and older with a disease called atypical Hemolytic Uremic Syndrome (aHUS). ULTOMIRIS is not used in treating people with ...
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10 Observational Study of Elizaria® in aHUS Patients
https://clinicaltrials.gov/ct2/show/NCT04749810
Patients will receive medication in accordance with the established requirements of national standards and protocols for the treatment of patients with aHUS ...
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11 Atypical Hemolytic Uremic Syndrome: New Challenges in the ...
https://www.karger.com/Article/FullText/508920
Lots of drugs have been associated with HUS, mainly drugs used in immunosuppressive therapy – solid organ transplant or hematopoietic stem ...
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12 PRO11 COSTS OF TREATMENT OF ATYPICAL HEMOLYTIC ...
https://www.valueinhealthjournal.com/article/S1098-3015(20)31430-3/fulltext
18 patients with aHUS were identificated as drug consumers in 2019. Eculizumab was the main treatment and most expensive medicine consumed by these patients ...
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13 Atypical Hemolytic-uremic Syndrome | Soliris | aHUS Treatment
https://www.orsinispecialtypharmacy.com/atypical-hemolytic-uremic-syndrome-ahus
Learn how Orsini Specialty Pharmacy helps treat patients who suffer from Atypical Hemolytic-uremic Syndrome (aHUS) with Soliris, a specialty medication.
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14 Proposal for individualized dosing of eculizumab in atypical ...
https://academic.oup.com/ndt/advance-article/doi/10.1093/ndt/gfac056/6541870
ABSTRACTBackground. Eculizumab is a lifesaving yet expensive drug for atypical haemolytic uraemic syndrome (aHUS).
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15 Clinical Trials for Atypical Hemolytic Uremic Syndrome ...
https://ahusnews.com/health-insights/clinical-trials-for-ahus/
Only a few treatment options exist for atypical hemolytic uremic syndrome (aHUS) and there's currently no cure for the disease.
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16 Soliris for the Treatment for PNH, aHUS, gMG and NMOSD
https://www.clinicaltrialsarena.com/projects/soliris-eculizumab-pnh-ahus/
Soliris (eculizumab) is a drug indicated for the treatment of paroxysmal nocturnal haemoglobinuria (PNH), atypical haemolytic uraemic syndrome ( ...
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17 Soliris (exulizumab) label - Accessdata.fda.gov
https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/125166s172lbl.pdf
hemoglobinuria (PNH) to reduce hemolysis (1.1). •. The treatment of patients with atypical hemolytic uremic syndrome. (aHUS) to inhibit complement-mediated ...
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18 Eculizumab a new drug to treat aHUS - Kidney Research UK
https://www.kidneyresearchuk.org/2019/04/16/eculizumab-a-new-drug-to-treat-ahus/
The great news for patients is that this new drug treatment means kidney transplants are now an option. Treating a patient with eculizumab ...
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19 A systematic review of eculizumab for atypical ... - BMJ Open
https://bmjopen.bmj.com/content/3/11/e003573
Discussion · Thus, overall, eculizumab appears to be a highly effective treatment for aHUS, although it was not compared head to head with optimal plasmapheresis ...
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20 Stopping Eculizumab Treatment Safely in atypical Haemolytic ...
https://www.isrctn.com/ISRCTN17503205?q=&filters=conditionCategory:Urological%20and%20Genital%20Diseases&sort=&offset=1&totalResults=602&page=1&pageSize=100&searchType=basic-search
Lifelong treatment with the drug Eculizumab is currently recommended for aHUS due to risk of relapse. Many physicians are now questioning the ...
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21 POS-055 UTILITY OF RITUXIMAB IN THE TREATMENT OF ...
https://www.sciencedirect.com/science/article/pii/S2468024922013547
The study shows that rituximab is an effective drug for the treatment of patients with antibody mediated aHUS. Its easy availability and lower cost make it ...
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22 Complement Inhibitors (Soliris® & Ultomiris®)
https://www.uhcprovider.com/content/dam/provider/docs/public/policies/comm-medical-drug/complement-inhibitors.pdf
UnitedHealthcare Commercial Medical Benefit Drug Policy ... o Laboratory results, signs, and/or symptoms attributed to aHUS (e.g., ...
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23 Optimal duration of treatment with eculizumab in atypical ...
https://link.springer.com/article/10.1007/s00467-019-4192-7
A short time ago, the same group of authors, this time measuring drug levels in 11 aHUS patients treated with eculizumab given at infusion ...
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24 Full article: Quantifying the economic effects of ravulizumab ...
https://www.tandfonline.com/doi/full/10.1080/13696998.2022.2027706
The terminal complement inhibitors eculizumab and ravulizumab are the only drug treatments for patients with aHUS approved by the US Food and Drug ...
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25 Soliris® (eculizumab) PLAN OF TREATMENT for aHUS for ...
https://www.palmettoinfusion.com/wp-content/uploads/2020/09/Soliris-Plan-of-Treatment-for-aHUS-for-Pediatric-Patients.pdf
* If the infusion is slowed, the total infusion time should not exceed 2 hours. 5. Frequency/dose: (Final volume is drug volume + equal diluent volume). Special ...
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26 Case Report: Variable Pharmacokinetic Profile of Eculizumab ...
https://www.frontiersin.org/articles/10.3389/fimmu.2020.612706/full
In view of the high costs, actual needs of the drug, and increasing evidence in literature, aHUS patients can be treated according to a ...
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27 What is atypical‑HUS? - ULTOMIRIS® (ravulizumab-cwvz)
https://ultomirishcp.com/ahus/about-aHUS
ULTOMIRIS treatment of aHUS should be a minimum duration of 6 months. Due to heterogeneous nature of aHUS events and patient-specific risk factors, treatment ...
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28 Atypical hemolytic uremic syndrome - ASH Publications
https://ashpublications.org/hematology/article/2016/1/217/21126/Atypical-hemolytic-uremic-syndrome
Availability of anticomplement therapy has revolutionized the management of aHUS, and can change the natural course of aHUS by inducing ...
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29 Outcomes in patients with atypical hemolytic uremic syndrome ...
https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-019-1314-1
Eculizumab was proven to be effective in patients with aHUS in five clinical studies [6,7,8,9,10], in which it resolved and prevented complement ...
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30 Eculizumab treatment of atypical hemolytic uremic syndrome
https://jhu.pure.elsevier.com/en/publications/eculizumab-treatment-of-atypical-hemolytic-uremic-syndrome
In summary, eculizumab therapy is now the standard of care in the prevention and treatment of episodes of aHUS. Prophylactic eculizumab should be used for renal ...
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31 Atypical Haemolytic Uraemic Syndrome (aHus) & Eculizumab
https://www.atypicalhus.co.uk/
NICE recommends Ravulizumab for the treatment of atypical haemolytic uraemic syndrome · The National Renal Complement Therapeutics centre is pleased to hear ...
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32 Soliris (Eculizumab): Uses, Dosage, Side Effects, Interactions ...
https://www.rxlist.com/soliris-drug.htm
Soliris (Eculizumab) may treat, side effects, dosage, drug interactions, ... for the treatment of patients with atypical hemolytic uremic syndrome (aHUS) to ...
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33 Discontinuing Eculizumab is Safe and Feasible in Patients ...
https://www.ashclinicalnews.org/news/from-the-blood-journals/written-in-blood/discontinuing-eculizumab-safe-feasible-patients-atypical-hemolytic-uremic-syndrome/
During a mean follow-up period of 19.8 months, 13 patients (23%) had an aHUS relapse. The average time between treatment discontinuation and ...
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34 Efficacy and Safety of Iptacopan (LNP023) in Adult Patients ...
https://www.recruiting-trials.novartis.com/clinicaltrials/study/nct04889430
The purpose of this Phase 3 study is to determine whether iptacopan (LNP023) is efficacious and safe for the treatment of aHUS in adult patients who are ...
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35 Iptacopan Recruiting Phase 3 Trials for Atypical Hemolytic ...
https://go.drugbank.com/drugs/DB16200/clinical_trials?conditions=DBCOND0061539&phase=3&purpose=treatment&status=recruiting
Iptacopan Recruiting Phase 3 Trials for Atypical Hemolytic Uremic Syndrome (aHUS) Treatment ... clinicaltrials.gov Identifier, Title, Drugs ...
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36 Atypical haemolytic uraemic syndrome - Services Australia
https://www.servicesaustralia.gov.au/atypical-haemolytic-uraemic-syndrome?context=23021
Make all initial applications for authority approval to prescribe eculizumab for the treatment of aHUS in writing and fax to the aHUS ...
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37 Soliris | European Medicines Agency - European Union
https://www.ema.europa.eu/en/medicines/human/EPAR/soliris
Soliris is a medicine used to treat adults and children with paroxysmal nocturnal haemoglobinuria (PNH) and atypical haemolytic uraemic syndrome (aHUS).
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38 First Report on Successful Conversion of Long-Term ...
https://www.frontierspartnerships.org/articles/10.3389/ti.2022.10846/full
Recurrent aHUS attributable to both complement factor mutations requires lifelong anti-C5 treatment due to high risk [6]. Our patient had been ...
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39 Eculizumab for treating atypical haemolytic uraemic syndrome
https://www.nice.org.uk/guidance/hst1/documents/atypical-haemolytic-uraemic-syndrome-ahus-eculizumab-final-evaluation-determination3
Atypical haemolytic uraemic syndrome (aHUS) is a chronic, rare, ... gains of a magnitude rarely seen for a new drug treatment. The.
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40 Eculizumab gets accelerated approval for aHUS - MDedge
https://www.mdedge.com/hematology-oncology/article/186568/anemia/eculizumab-gets-accelerated-approval-ahus
The US Food and Drug Administration (FDA) has granted accelerated approval for eculizumab (Soliris) to treat patients with atypical ...
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41 Pediatric Pharmacotherapy - The University of Virginia
https://med.virginia.edu/pediatrics/wp-content/uploads/sites/237/2015/12/201202.pdf
This additional indication makes eculizumab the first drug to be approved for the treatment of aHUS.1. Recent clinical experience has also suggested that.
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42 The long-acting C5 inhibitor, Ravulizumab, is effective and ...
https://www.kidney-international.org/article/S0085-2538(20)30152-6/pdf
tive in treating aHUS, eculizumab requires a standard treat- ment regimen of intravenous infusions every 2 weeks in.
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43 Complement-mediated hemolytic uremic syndrome in children
https://www.uptodate.com/contents/complement-mediated-hemolytic-uremic-syndrome-in-children
Stopping nephrotoxic drugs or those that are implicated in the etiology of HUS. ○Initiation of dialysis therapy in patients with symptomatic ...
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44 Eculizumab - Wikipedia
https://en.wikipedia.org/wiki/Eculizumab
Eculizumab, sold under the brand name Soliris among others, is a medication used to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic ...
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45 5.01.571 C3 and C5 Complement Inhibitors
https://www.premera.com/medicalpolicies/5.01.571.pdf
drugs used to treat a rare blood condition called paroxysmal nocturnal ... In both PNH and aHUS, the genetic changes affect how the body.
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46 When the Patient Is a Gold Mine - Bloomberg.com
https://www.bloomberg.com/news/features/2017-05-24/when-the-patient-is-a-gold-mine-the-trouble-with-rare-disease-drugs
Patients with aHUS, for instance, faced years of kidney dialysis ... But orphan drugs have also caused a seismic shift in treatment costs.
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47 An international consensus approach to the management of ...
https://www.ouhsc.edu/platelets/documents/c-tmaarticle.pdf
Major progress has been made since the early 2000s in the understanding of the pathophysiology of atypical hemolytic uremic syndrome (aHUS) and its treatment.
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48 Interventions for atypical haemolytic uraemic syndrome - 2021
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD012862.pub2/abstract
We searched the literature extensively and found five studies which tested therapies for aHUS. In four studies the treatment used was eculizumab ...
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49 SOLIRIS aHUS - Alexion Access Navigator
https://alexionaccessnavigator.com/soliris/ahus
SOLIRIS is a complement inhibitor indicated for the treatment of patients with atypical hemolytic uremic syndrome (aHUS) to inhibit complement-mediated ...
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50 FDA approves Ultomiris for AHUS in adults and children
https://www.thepharmaletter.com/article/fda-approves-ultomiris-for-ahus-in-adults-and-children
The US Food and Drug Administration has approved Ultomiris (ravulizumab-cwvz) for the treatment of atypical hemolytic uremic syndrome (aHUS) to inhibit ...
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51 Soliris (eculizumab) and Ultomiris (ravulizumab-cwvz) Medical ...
https://www.myprime.com/content/dam/prime/memberportal/forms/AuthorForms/BCBSKS/Program_Summaries/KS_MDC_Soliris_and_Ultomiris_ProgSum.pdf
treatment of secondary HUS is withdrawal of offending drug or treating triggering ... exchange, was the first-line treatment option for patients with aHUS.
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52 Soliris® (eculizumab) Approved by FDA for All Patients with ...
https://www.businesswire.com/news/home/20110923005612/en/Soliris%C2%AE-eculizumab-Approved-by-FDA-for-All-Patients-with-Atypical-Hemolytic-Uremic-Syndrome-aHUS
Soliris® (eculizumab) Approved by FDA for All Patients with Atypical Hemolytic Uremic Syndrome (aHUS). - First and Only Approved Treatment ...
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53 Atypical Hemolytic Uremic Syndrome (aHUS) Treatment Options
https://specialtyinfusion.com/2022/02/18/atypical-hemolytic-uremic-syndrome-treatment-options/
FDA has approved it for the treatment of aHUS. Long-term renal and TMA outcomes can be enhanced and improved in patients with atypical hemolytic ...
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54 Physician's guide to prescribing for patients with aHUS
https://www.health.gov.il/UnitsOffice/HD/MTI/Drugs/risk/DocLib/Soliris-aHUS.pdf
SOLIRIS® therapy must not be initiated in aHUS patients: ... Effects of Drug Treatment” that appears on the homepage of the Ministry of Health's.
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55 Eculizumab as a treatment for atypical hemolytic ... - Nefrología
https://www.revistanefrologia.com/index.php?p=revista&tipo=pdf-simple&pii=S2013251419300057
It is one of the drugs used in the treatment of refractory multiple myeloma.1–4 The onset of atypical haemolytic uremic syndrome (aHUS) associated with the ...
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56 FDA OKs Drug Offering Hope for HUS Treatment
https://www.foodsafetynews.com/2011/09/fda-approves-drug-offering-hope-for-hus-treatment/
A drug that holds significant promise for treating the devastating effects of hemolytic uremic syndrome (HUS) has been approved for limited ...
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57 Long-Term Efficacy and Safety of the Long-Acting ...
https://www.kireports.org/article/S2468-0249(21)01032-9/fulltext
Atypical hemolytic uremic syndrome (aHUS) is a rare, complex, multisystem disease of dysregulated complement activity, characterized by ...
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58 Priority Review Granted for Soliris for aHUS - MPR - eMPR.com
https://www.empr.com/home/news/drugs-in-the-pipeline/priority-review-granted-for-soliris-for-ahus/
... License Agreement (sBLA) for Soliris (eculizumab) for the treatment of patients with atypical hemolytic uremic syndrome (aHUS).
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59 Atypical hemolytic uremic syndrome - Orphanet
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=2134
The recommended first line targeted therapy is with eculizumab which blocks complement terminal pathway, thus halting endothelial damage and ensuing thrombotic ...
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60 Webinar: Rare Disease Spotlight | aHUS diagnosis, treatment ...
https://www.youtube.com/watch?v=uzta1aGpwas
Mar 7, 2022
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61 The Importance of Eculizumab in the Treatment of Atypical ...
https://www.cureus.com/articles/97074-the-importance-of-eculizumab-in-the-treatment-of-atypical-hemolytic-uremic-syndrome
The availability of eculizumab revolutionized the prognosis of patients with severe forms of aHUS presentation. This monoclonal antibody has an ...
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62 Soliris Meets Key Endpoints in aHUS Trial
https://www.drugdiscoverytrends.com/soliris-meets-key-endpoints-in-ahus-trial/
By Drug Discovery Trends Editor | December 16, 2010 ... Hemolytic Uremic Syndrome (aHUS) who are resistant to plasma therapy met primary and key secondary ...
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63 aHUS patients to receive 'interim' funding for drug | CTV News
https://www.ctvnews.ca/health/ontario-to-provide-interim-funding-for-patients-with-ultra-rare-disease-1.2252853
Several studies have found Soliris to be effective in helping to control aHUS. In a small 2013 clinical trial, researchers found the drug was ...
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64 Eculizumab (Intravenous Route) Precautions - Mayo Clinic
https://www.mayoclinic.org/drugs-supplements/eculizumab-intravenous-route/precautions/drg-20070917?p=1
Eculizumab injection is used to treat a type of blood disease called paroxysmal nocturnal hemoglobinuria (PNH). This medicine helps reduce red blood cell ...
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65 B.C. government approves coverage of expensive drug for ...
https://globalnews.ca/news/3873332/coverage-approved-for-expensive-drug-soliris/
The medicine costs approximately $750000 a year and can improve a patient's condition who's living with aHUS.
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66 Patients need much less medication in rare kidney disease
https://www.radboudumc.nl/en/news-items/2022/patients-need-much-less-medication-in-rare-kidney-disease
Lifelong use of the drug eculizumab is not necessary in the rare kidney disease atypical hemolytic uremic syndrome (aHUS). Most patients already benefit from ...
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67 Learning from One Indication to the Next - Certara
https://www.certara.com/app/uploads/2020/06/CS_LearningFromOneIndicationToTheNext.pdf
treatment of PNH based on evidence of effectiveness from clinical studies.2. Solution ... measure the drug's exposure and inform pediatric dosing for. aHUS.
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68 Critical appraisal of eculizumab for atypical hemolytic uremic ...
https://www.dovepress.com/critical-appraisal-of-eculizumab-for-atypical-hemolytic-uremic-syndrom-peer-reviewed-fulltext-article-JBM
Currently, the drug has been used worldwide for the treatment of aHUS. A recent consensus document almost uniformly recommended that, ...
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69 Soliris (eculizumab): Basics, Side Effects & Reviews - GoodRx
https://www.goodrx.com/soliris/what-is
Soliris (eculizumab) is used to treat many rare, blood- and nerve-related problems. This medication is given by a healthcare provider as an ...
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70 Empaveli New Drug Facts Blast
https://dss.mo.gov/mhd/cs/advisory/rdac/pdf/empaveli-new-drug-fact-blast.pdf
Although Empaveli is not the first medication approved to treat PNH, it is the only C3 ... Abbreviations: aHUS = atypical hemolytic uremic syndrome; ...
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71 Soliris (eculizumab) FDA Approval History - Drugs.com
https://www.drugs.com/history/soliris.html
the treatment of patients with atypical hemolytic uremic syndrome (aHUS) to inhibit complement-mediated thrombotic microangiopathy; the ...
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72 Living Donor Transplantation in aHUS Cohort At Risk for ...
https://ajkdblog.org/2017/09/20/living-donor-transplantation-in-ahus-cohort-at-risk-for-recurrence/
Using this approach rather than a preemptive blanket treatment protocol in many such patients will afford great savings in resources. The ...
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73 a case series of 7 treated patients - Wiley Online Library
https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.14910
Atypical haemolytic uraemic syndrome (aHUS) is the triad ... offending drug, all patients responded to eculizumab therapy.
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74 Ultomiris: Alternatives, cost, side effects, dosage, and more
https://www.medicalnewstoday.com/articles/drugs-ultomiris
In 2018, the Food and Drug Administration (FDA) first approved Ultomiris to treat PNH. And in 2019, Ultomiris received further FDA approval to treat aHUS.
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75 Could this be the UK's most expensive medicine? - CNBC
https://www.cnbc.com/2015/01/28/nhs-england-most-expensive-drug-funding-for-eculizumab-has-been-given-green-light.html
The drug, whose trade name is Eculizumab, will help treat a life-threatening, genetic disorder that affects up to 200 Brits. The drug would help ...
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76 FDA Grants "Fast Track" to Omeros' Complement Inhibitor ...
https://www.prnewswire.com/news-releases/fda-grants-fast-track-to-omeros-complement-inhibitor-oms721-for-ahus-300117622.html
Omeros is currently evaluating the drug in a Phase 2 clinical trial for the treatment of aHUS and other thrombotic microangiopathies (TMAs).
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77 CDEC RECORD OF ADVICE - ECULIZUMAB (Soliris - CADTH
https://www.cadth.ca/sites/default/files/cdr/advice/cdr-advice-Soliris-aHUS-June-2-2015.pdf
Eculizumab for the treatment of aHUS was reviewed by CDEC in 2013 and ... CADTH Common Drug Review (CDR)–participating drug plans' request ...
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78 Eculizumab Therapy Leads to Rapid Resolution of ... - Hindawi
https://www.hindawi.com/journals/ah/2014/295323/
Eculizumab is highly effective in controlling complement activation in patients with the atypical hemolytic uremic syndrome (aHUS). However, the course of ...
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79 Terminal Complement Inhibitor Eculizumab in Atypical ...
https://www.nejm.org/doi/full/10.1056/nejmoa1208981
At the data-cutoff point, the median duration of eculizumab treatment was 64 weeks (range, 2 to 90). In trial 2, patients were also treated with ...
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80 Atypical HUS India (@ahusindia) / Twitter
https://twitter.com/ahusindia
Recruiting to aHUS Trials is not easy - aHUS Alliance Action ... What might the future may hold for potential new #drugs to treat #aHUS, a rare form of #TMA ...
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81 Atypical hemolytic-uremic syndrome: MedlinePlus Genetics
https://medlineplus.gov/genetics/condition/atypical-hemolytic-uremic-syndrome/
› Genetics › Genetic Conditions
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82 Treatment - aHUS Foundation
https://www.ahus.org/treatment
Right now there is no cure for Atypical HUS - the only reason there is not a standard treatment is because each case is different, but even that may change over ...
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83 ULTOMIRIS Clinical Pharmacology Drug Monograph
https://www.wellrx.com/ULTOMIRIS/monographs/
The recommended adult dosing regimen for PNH, aHUS, and gMG consists of a loading dose followed by maintenance dose every 8 weeks, offering an advantage over ...
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84 Eculizumab (Soliris) - Pharmacy Times
https://www.pharmacytimes.com/view/eculizumab-soliris
Eculizumab (Soliris) is FDA-approved for the treatment of atypical hemolytic uremic syndrome (aHUS) in adult and pediatric patients to ...
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85 Efficacy of eculizumab in paediatric aHUS - Nature
https://www.nature.com/articles/nrneph.2016.24
Eculizumab is currently the only approved treatment for atypical haemolytic uraemic syndrome (aHUS), but data in paediatric patients are ...
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86 NHS England establishes national service to treat rare kidney ...
https://www.england.nhs.uk/2016/05/kidney-condition-ahus/
The drug Eculizumab is the only known effective treatment for this condition, as recommended by NICE in January 2015. NICE stipulated a number ...
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87 Treatment for HUS | About HUS
https://about-hus.com/hus_treatment
Eculizumab has been proven effective in atypical or diarrhea-negative HUS (D- HUS). In the Germany epidemic, early studies suggested that eculizumab was ...
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88 Soliris (Eculizumab) - Myasthenia Gravis News
https://myastheniagravisnews.com/soliris-eculizumab-for-myasthenia-gravis/
Soliris is also approved by the U.S. Food and Drug Administration (FDA) for the treatment of paroxysmal nocturnal hemoglobinuria, atypical ...
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89 Eculizumab - Side Effects, Uses, Dosage, Overdose ... - RxWiki
https://www.rxwiki.com/eculizumab
Eculizumab is a prescription medication used to treat Paroxysmal Nocturnal Hemoglobinuria (PNH), atypical Hemolytic Uremic Syndrome (aHUS), ...
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90 Perspectives on Treatment Selection for Atypical Hemolytic ...
https://www.medscape.org/viewarticle/835224_2
Listen to Dr Asif review how to diagnose and treat patients with atypical hemolytic ... uses of products regulated by the US Food and Drug Administration, ...
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91 Soliris biosimilar russia - J-Shop
https://j-shop.fr/soliris-biosimilar-russia.html
... late 2023 for aHUS, until 2027 for gMG and until 2029 for NMOSD (orphan drug exclusivity for SOLIRIS for treating PNH in Europe previously expired). n.
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92 Getting to know aHUS - Alexion
https://gettoknowahus.com.au/
Atypical Haemolytic Uraemic Syndrome (aHUS) is a rare, lifelong condition that can rapidly progress into a medical emergency – resulting in irreversible multi- ...
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93 Atypical Hemolytic-Uremic Syndrome - DoveMed
https://www.dovemed.com/diseases-conditions/atypical-hemolytic-uremic-syndrome/
Dialysis · Plasma therapy, plasma exchange · Renal transplantation; sometimes a combined liver-kidney transplant is resorted to · Use of complement ...
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94 Rare Kidney Diseases Market by Target Indications, Type of ...
https://www.yahoo.com/now/rare-kidney-diseases-market-target-133000767.html
... identify novel drugs that can efficiently treat rare kidney disorders. ... and Ultomiris® (Atypical Hemolytic Uremic Syndrome (aHUS), ...
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