❤️ Why Do Deleterious Alleles Persist

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1
https://evolution.berkeley.edu/deleterious-genes/
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2
https://bio.libretexts.org/Bookshelves/Cell_and_Molecular_Biology/Book%3A_Biofundamentals_(Klymkowsky_and_Cooper)/08%3A_Peptide_bonds_polypeptides_and_proteins/8.16%3A_Why_do_harmful_alleles_persist
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3
https://sciencing.com/deleterious-genes-14053.html
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4
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111778
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5
https://onlinelibrary.wiley.com/doi/full/10.1111/eva.12691
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6
https://www.nature.com/scitable/knowledge/library/natural-selection-genetic-drift-and-gene-flow-15186648/
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7
https://www.pnas.org/doi/10.1073/pnas.1424949112
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8
https://www.sciencedirect.com/science/article/pii/S0960982218311941
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9
https://www.cell.com/current-biology/pdf/S0960-9822(18)31194-1.pdf
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10
https://www.jstor.org/stable/2640531
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11
https://gsejournal.biomedcentral.com/articles/10.1186/s12711-019-0456-8
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12
https://www.frontiersin.org/articles/10.3389/fimmu.2015.00105/full
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13
https://academic.oup.com/mbe/article/33/11/2899/2272128
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14
https://www.biorxiv.org/content/10.1101/2020.04.04.025841v1
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15
https://en.wikipedia.org/wiki/Mutation%E2%80%93selection_balance
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16
https://www.annualreviews.org/doi/abs/10.1146/annurev-ecolsys-110411-160257
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17
https://journals.asm.org/doi/10.1128/mBio.01302-15
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18
http://agrawal.eeb.utoronto.ca/files/2013/06/afa_mcw_2012.pdf
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19
https://biologywise.com/what-does-deleterious-mutation-mean
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20
https://homework.study.com/explanation/are-rare-or-common-recessive-deleterious-alleles-more-rapidly-reduced-in-frequency-in-a-population-via-natural-selection-why.html
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21
https://www.inverse.com/article/36907-genetic-disease-mutation-selection-balance
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22
https://sicklecellanemianews.com/news/why-sickle-cell-and-other-harmful-mutations-persist-across-generations/
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23
https://www.pbs.org/wgbh/evolution/educators/course/session7/explain_b_pop1.html
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24
https://nautil.us/why-hasnt-natural-selection-eliminated-heritable-disease-236177/
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25
http://home.uchicago.edu/~rper/Selected_Publications/Perlman_Why_Disease_Persists_2005.pdf
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26
https://www.cambridge.org/core/journals/genetics-research/article/effect-of-background-selection-against-deleterious-mutations-on-weakly-selected-linked-variants/E9696E5DFDEAED48719311D179D0C959
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27
https://hal.archives-ouvertes.fr/hal-02105889/document
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28
http://www.biology.arizona.edu/biomath/tutorials/Power/Applications/MutSelBal.html
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29
https://journals.sagepub.com/doi/10.1111/j.1467-8721.2008.00613.x
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30
https://genome.cshlp.org/content/19/9/1553.long
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31
https://www.science.org/doi/10.1126/sciadv.aau0757
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32
https://www.youtube.com/watch?v=AW3bqHvdjDA
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33
https://quizlet.com/199120730/evolution-exam-2-flash-cards/
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34
https://www.quora.com/Why-do-recessive-alleles-persist-in-people-over-numerous-generations
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35
https://www.researchgate.net/figure/Relationship-between-the-mean-persistence-time-of-a-deleterious-allele-in-a-patchy_fig1_13781899
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36
https://plantfacts.osu.edu/resources/hcs300/evol.htm
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37
https://www.k-state.edu/biology/p2e/evolutionary-mechanisms-ii-mutation-genetic-drift-migration-and-non-random-mating.html
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38
https://www.ndsu.edu/pubweb/~mcclean/popgen/charlesworth%20et%20al%20-%20the%20effect%20of%20deleterious%20mutations%20on%20neutral%20molecular%20variation.pdf
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39
https://www3.nd.edu/~mpfrende/Evolutionary_Biology/Problem%20Sets/Problem%20Set%202%20F2016%20KEY.pdf
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40
https://reich.hms.harvard.edu/sites/reich.hms.harvard.edu/files/inline-files/2015_NG_Do_Deleterious_Load_Concatenated_1.pdf
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41
https://pubag.nal.usda.gov/catalog/7266947
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42
https://www.uvm.edu/~dstratto/bcor102/readings/04_Mutation-selection-balance-briefnotes.pdf
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43
https://www.oxfordbibliographies.com/view/document/obo-9780199941728/obo-9780199941728-0124.xml
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44
https://prelights.biologists.com/highlights/estimates-of-genetic-load-in-small-populations-suggest-extensive-purging-of-deleterious-alleles/
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45
https://uu.diva-portal.org/smash/get/diva2:1175751/FULLTEXT01.pdf
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46
https://www.ucr.cgt.fr/fbri/deleterious-alleles-are-eliminated-from-populations-by
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47
https://www.chegg.com/homework-help/questions-and-answers/humans-deleterious-alleles-persist-population-processes-account-addition-deleterious-reces-q47406869
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48
https://borealisdata.ca/dataset.xhtml?persistentId=doi:10.5683/SP2/NB2KLF
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49
https://www.apsnet.org/edcenter/disimpactmngmnt/topc/PopGenetics/Pages/NaturalSelection.aspx
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50
https://royalsocietypublishing.org/doi/10.1098/rstb.2021.0010
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51
https://www.dogenes.com/essays/mutation.html
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52
https://faq-blog.com/why-do-deleterious-alleles-persist-in-populations
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53
https://petrov.stanford.edu/pdfs/0112.pdf
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54
https://europepmc.org/article/pmc/4552954
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55
https://homepage.univie.ac.at/Reinhard.Buerger/04WhitlockBuerger.pdf
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56
https://www.nku.edu/~whitsonma/Bio150LSite/Lab%2012%20Pop%20Gen/Bio150LPopGen.html
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57
https://www.sciencedaily.com/releases/2021/10/211012130741.htm
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58
https://arxiv.org/pdf/1302.2710
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59
https://lup.lub.lu.se/student-papers/record/4934568/file/4934571.pdf
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60
https://home.csulb.edu/~acarter3/course-evolution-fa2022/files/bio312-pop-gen-summary.pdf
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61
https://www.amherst.edu/media/view/181315/original/AlleleA1-Key
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62
https://www.ucl.ac.uk/~ucbhdjm/courses/b242/OneGene/MutSel.html
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63
https://oneclass.com/homework-help/biology/141837-why-do-deleterious-alleles-pers.en.html
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64
https://www.research.ed.ac.uk/files/84241386/Removal_of_alleles_by_genome_editing.pdf
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65
https://www.bionity.com/en/encyclopedia/Heterozygote_advantage.html
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66
https://scienceprimer.com/population-genetics-drift-and-selection
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67
http://evolution-textbook.org/content/free/notes/ch23_Notes.html
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68
https://pdfs.semanticscholar.org/719e/d26b936ad32fb5dec1f097f397a9fb86902b.pdf
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69
https://www.molecularecologist.com/2020/03/04/how-to-handle-the-burden-of-deleterious-mutations/
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70
https://www.numerade.com/ask/question/many-deleterious-genes-are-recessive-and-therefore-are-expressed-only-in-the-homozygote-many-of-them-are-also-utterly-lethal-many-ofthem-have-also-been-present-in-the-human-gene-pool-for-hun-68288/
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71
https://moviecultists.com/why-do-deleterious-alleles-persist-in-populations
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72
https://www.coursehero.com/study-guides/sanjacinto-biology1/283/
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73
http://oapr.bru.ac.th/t1/pfvx/why-do-deleterious-alleles-persist-in-populations
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74
https://medlineplus.gov/genetics/understanding/mutationsanddisorders/evolution/
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75
http://www.mheresearchfoundation.org/Mutation.html
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76
https://accesson.kisti.re.kr/upload2/article/originPdf/000608/ATN0006084980.pdf
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77
https://offticket-koeln.de/inbred-humans.html
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78
https://books.google.com/books?id=EBBsBgAAQBAJ&pg=PA452&lpg=PA452&dq=why+do+deleterious+alleles+persist&source=bl&ots=-x-cygwvtR&sig=ACfU3U0apNGlQnAxlJksZ4zsxDy56cgsAQ&hl=en&sa=X&ved=2ahUKEwiBjuP1rcb7AhVRkIkEHfSYB_gQ6AF6BQiyAhAD
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79
https://www.nejm.org/doi/full/10.1056/NEJMoa1616361
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