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1 The management of anti-tuberculosis drug-induced ... - PubMed
https://pubmed.ncbi.nlm.nih.gov/11263519/
The recurrence rate of hepatotoxicity in the retreatment of tuberculosis is higher in the reintroduction of a full-dose regimen including pyrazinamide, ...
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2 hepatotoxicity-of-antituberculosis-therapy.pdf
https://www.thoracic.org/statements/resources/mtpi/hepatotoxicity-of-antituberculosis-therapy.pdf
During treatment of latent TB infection (LTBI) ala- nine aminotransferase (ALT) monitoring is recommended for those who chronically consume alcohol, take ...
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3 An Official ATS Statement: Hepatotoxicity of Antituberculosis ...
https://www.atsjournals.org/doi/abs/10.1164/rccm.200510-1666ST
Drug-induced liver injury (DILI) is a problem of increasing significance, but has been a long-standing concern in the treatment of tuberculosis (TB) ...
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4 Hepatotoxicity caused by first-line anti-TB drugs in adults
https://www.uptodate.com/contents/image?imageKey=ID/109447
* First-line antituberculous drugs include isoniazid, rifampin, pyrazinamide, and ethambutol. Isoniazid, rifampin, and pyrazinamide are potentially hepatotoxic; ...
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5 Safety of 3 Different Reintroduction Regimens of ...
https://academic.oup.com/cid/article/50/6/833/417605
The most common adverse effect leading to interruption of therapy is hepatotoxicity [1]. Anti-TB drug–induced hepatotoxicity (DIH) is associated with a ...
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6 Standard anti-tuberculosis treatment and hepatotoxicity
https://erj.ersjournals.com/content/29/2/347
Three randomised controlled trials involving combination therapy with isoniazid, rifampicin and pyrazinamide in the initial phase showed that daily treatment ...
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7 Anti-Tuberculosis Drug Induced Hepatotoxicity and ...
https://www.dovepress.com/anti-tuberculosis-drug-induced-hepatotoxicity-and-associated-factors-a-peer-reviewed-fulltext-article-HMER
The incidence of hepatotoxicity is relatively high among TB patients taking first-line anti-TB drugs. Thus, the liver function of patients with ...
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8 The clinical impact of drug-induced hepatotoxicity on anti ...
https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-019-1256-y
by JH Song · 2019 · Cited by 10 —
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9 Antituberculosis drug‐induced hepatotoxicity: Concise up‐to ...
https://onlinelibrary.wiley.com/doi/10.1111/j.1440-1746.2007.05207.x
Recommended standard treatment for adult respiratory TB is a regimen of isoniazid, rifampicin, and pyrazinamide for 2 months, followed by 4 ...
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10 Treatment of TB in Patients With Drug-Induced Hepatitis
https://www.medscape.com/viewarticle/723076
... CID article on a randomized controlled trial of various regimens for re-starting TB treatment in persons with drug induced hepatitis.
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11 Ketogenic Diet and Drug-Induced Hepatotoxicity During ...
https://journals.lww.com/jpgnr/Fulltext/2022/08000/Ketogenic_Diet_and_Drug_Induced_Hepatotoxicity.7.aspx
When therapy with hepatotoxic drugs is being considered, all other possible ... During the fourth month of anti-TB treatment with isoniazid, rifampin, ...
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12 Increased risk of hepatotoxicity and temporary drug ...
https://www.sciencedirect.com/science/article/pii/S120197122030504X
Careful monitoring of liver transaminases while receiving TB treatment during pregnancy is mandatory, as well as ensuring adequate measures with adjustment of ...
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13 Hepatotoxicity during Treatment for Tuberculosis in ... - PLOS
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157725
The cumulative incidence rate of hepatotoxicity in PLWHA following the use of drugs for TB treatment was 30.6% in the population studied. The ...
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14 MONITORING FOR HEPATOTOXICITY DURING ...
https://www.info.gov.hk/tb_chest/doc/hepatotoxicity.pdf
Treatment of tuberculosis (TB) involves several drugs in combination for six or more months. An updated set of guidelines has been published by a working group ...
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15 An approach to the management of drug induced liver injury in ...
https://sahivsoc.org/Files/Thurs_Colin_Menezes%20TB%20DILI.pdf
and started on TB therapy – noted jaundice 6 weeks later. LFTs: TB 100,CB 90, ALT 50, GGT 30. ... Hepatotoxicity is one of the most important adverse drug.
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16 Reintroduction Regimens After Hepatitis During Anti ...
https://clinicaltrials.gov/ct2/show/NCT01395654
Despite the availability of effective chemotherapeutic agents that exist to treat this illness, hepatotoxicity during first-line drugs anti-tuberculosis ...
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17 Hepatotoxicity Associated With Isoniazid Preventive Therapy
https://jamanetwork.com/journals/jama/fullarticle/189096
Context Isoniazid preventive therapy for latent tuberculosis (TB) infection has been debated because of the risk of hepatotoxicity.
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18 Tuberculosis Drug-Induced Liver Injury - Journal Unair
https://e-journal.unair.ac.id/JR/article/download/17920/10661/73687
Effective TB treatment uses rifampicin, isoniazid, pyrazinamide, and ethambutol. The use of these drugs has a risk of hepatotoxic side ...
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19 Prevalence of Hepatotoxicity From Antituberculosis Therapy
https://journals.sagepub.com/doi/10.1177/2150131916642431
ATT drugs may cause hepatotoxicity ranging from a transient asymptomatic rise in liver enzymes to acute liver failure. The reported mortality from DILI after ...
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20 A Pharmacology Perspective on Simultaneous Tuberculosis ...
https://journals.asm.org/doi/10.1128/AAC.01215-19
Among patients with drug-resistant TB, we would recommend the newly recommended regimen (16) of three class A drugs (fluoroquinolone, ...
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21 Tuberculosis and liver disease: management issues
http://www.tropicalgastro.com/articles/33/2/tuberculosis-and-liver-disease-management.html
Granulomatous hepatitis and tubercular liver abscess are treated like any other extra-pulmonary tubercular lesions without any extra risk of hepatotoxicity by ...
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22 Anti-tuberculosis treatment: induced hepatotoxicity - IFCC
https://www.ifcc.org/media/478628/ejifcc2020vol31no3pp242-247.pdf
Hepatotoxicity is the most commonly reported ADR in patients treated with anti-tubercular drugs such as isoniazid, rifampicin and pyrazinamide. Clinical ...
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23 Safety of Fluoroquinolone Use in Patients with Hepatotoxicity ...
https://www.jstor.org/stable/40309358
Levofloxacin and moxifloxacin caused no additional hepatotoxicity when they were used b ... Most first-line drugs for treatment of tuberculosis (TB),.
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24 First line anti-tuberculosis induced hepatotoxicity: incidence ...
https://www.panafrican-med-journal.com/content/article/25/167/full
Hepatotoxicity is the most common adverse reaction of anti-TB treatment that leads to interruption of therapy. The exact mechanism of ATDH is ...
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25 Anti-Tuberculosis Drug Induced Liver Injury and ...
https://www.scirp.org/journal/paperinformation.aspx?paperid=101189
... anti-tuberculosis drug-induced hepatotoxicity. Ursodeoxycholic acid is the only FDA approved drug for the treatment of primary biliary cholangitis and ...
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26 An Investigation of the Risk Factors Associated With Anti ...
https://www.frontiersin.org/articles/10.3389/fphar.2021.708522/full
Many factors may cause treatment interruptions in patients with TB; one of the most important is anti-tuberculosis drug-induced liver injury (AT ...
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27 Method To Prevent Liver Damage Induced By Anti ...
https://www.sciencedaily.com/releases/2008/09/080919142358.htm
Preventive therapy of contacts causes severe hepatotoxicity more often than curative treatment of clinical tuberculosis.
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28 Risk of hepatitis with various reintroduction regimens of anti ...
https://www.tandfonline.com/doi/full/10.1080/14787210.2020.1714436
This report of the American Thoracic Society provides guidance on treatment of tuberculosis and definition and management of ATT hepatotoxicity and sequential ...
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29 Isoniazid (TB treatment) Hepatotoxicity among Drug Users
https://www.natap.org/2003/feb/020103_10.htm
The treatment of LTI with isoniazid among these patients while they are enrolled in methadone maintenance programs has proved to be a cost-effective approach.
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30 Hepatotoxicity and antituberculosis therapy: time to revise UK ...
https://thorax.bmj.com/content/64/10/918
Hepatotoxicity associated with antituberculosis therapy is an important clinical problem. Guidelines recommend baseline liver function tests (LFTs) before ...
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31 Antitubercular Drug Induced Hepatotoxicity: A Review
https://ejmcm.com/article_4990_eef4948246ee32ef2143d39a2d682607.pdf
TB is a curable disease that is properly treated with anti-. TB drugs. Anti-TB treatment is the reason for the most frequent adverse effects that are.
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32 Drug-induced hepatotoxicity and tuberculosis in a hospital ...
https://www.medwave.cl/investigacion/estudios/6135.html?lang=en
Hepatotoxicity is a serious, disturbing and sometimes fatal side effect that may occur once these patients start treatment with specific drugs. Slight increases ...
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33 ATT-induced Hepatotoxicity: Culprit Drug
https://japi.org/s2a4d4b4/att-induced-hepatotoxicity-culprit-drug
Hepatotoxicity is most serious one which not only leads to high morbidity and mortality, but also decreases anti TB treatment effectiveness, owing to non ...
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34 Drug-induced Hepatotoxicity of Anti-tuberculosis Drugs and ...
https://jkms.org/DOIx.php?id=10.3346/jkms.2015.30.2.167
Tuberculosis (TB) remains a huge health burden worldwide (1). The currently recommended first-line treatment for TB is a regimen of isoniazid ( ...
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35 Chapter 6 Treatment of Tuberculosis Disease - CDC
https://www.cdc.gov/tb/education/corecurr/pdf/chapter6.pdf
TB Disease Treatment Regimens for Specific Situations . ... The implications of drug-induced hepatitis for patients with marginal hepatic reserve are.
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36 Rifampicin-isoniazid induced fatal fulminant hepatitis during ...
https://www.ijccm.org/doi/IJCCM/pdf/10.4103/0972-5229.68226
Keywords: Acute fulminant hepatitis, latent tuberculosis infection, antituberculosis treatment, hepatotoxicity. Rifampicin-isoniazid induced fatal fulminant.
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37 Relationship of anti-tuberculosis drug-induced liver injury and ...
https://www.scielo.br/j/bjid/a/7QZRpWykMk36YpzGf36KZFp/?lang=en&format=pdf
Hepatotoxicity. Pulmonary tuberculosis. a b s t r a c t. Setting: Treatment of tuberculosis (TB) can result in Drug-Induced Liver Injury ...
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38 Drug Induced Hepatotoxicity of Antituberculosis Drugs and ...
https://journal.chestnet.org/article/S0012-3692(16)54524-3/fulltext
Hepatotoxicity of anti-tuberculosis drug was defined when serum aspartate aminotransferase(AST) or alanin aminotransferase(ALT) exceed three times upper limit ...
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39 Short-Course Treatment for TB May Increase Liver Injury - AAFP
https://www.aafp.org/pubs/afp/issues/2003/0215/p828.html
However, because of potential toxicity, especially hepatitis, and poor adherence to the medication regimen, a shorter two-month course of ...
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40 Development of a prediction system for anti-tuberculosis drug ...
https://www.nature.com/articles/hgv201614
Drug-induced liver injury (DILI) is a common adverse drug reaction in patients receiving antituberculosis (anti-TB) treatment.
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41 Evaluation of Drug Induced Liver Injury in Tuberculosis and ...
https://austinpublishinggroup.com/gastroenterology/fulltext/ajg-v4-id1086.php
When patients develop DILI, additional modes of anti- TB treatment are used. Once DILI occurs, all anti-TB drugs should be withheld until a complete resolution ...
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42 Metabolism and hepatotoxicity of pyrazinamide
https://dmd.aspetjournals.org/content/dmd/early/2021/06/01/dmd.121.000389.full.pdf
on the WHO's list of essential medicines for TB treatment. ... hepatotoxic anti-TB drugs such as INH and RIF, PZA was initially reported ...
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43 Evidence tables – Management of treatment interruptions RQ Z
https://www.nice.org.uk/guidance/ng33/documents/tuberculosis-update-appendix-d92
Treatment with the hepatotoxic drugs (isoniazid, rifampicin, and pyrazinamide) was ... The management of anti-tuberculosis drug-induced hepatotoxicity.
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44 Reintroduction of TB Meds Following Hepatotoxicity
https://www.reliasmedia.com/articles/19418-reintroduction-of-tb-meds-following-hepatotoxicity
Drug-related hepatotoxicity during treatment for tuberculosis is a common barrier to initiation of antimycobacterial. While most hepatotoxicity results in ...
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45 Factors Enhancing Drug-induced Hepatotoxicity among Thai ...
https://www.jcdr.net/articles/PDF/14008/44816_CE[Ra1]_F(SHU)_PF1(AKA_KM)_PFA(AKA_KM)_PN(SL).pdf
The currently standard treatment for anti-TB is a regimen which comprised with Isoniazid (INH), Rifampicin (RMP), Pyrazinamide (PZA) and.
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46 Comparison of Drug Induced Hepatotoxicity Incident of Fixed ...
https://iopscience.iop.org/article/10.1088/1742-6596/1764/1/012012/pdf
The regimen for treatment of pulmonary tuberculosis is isoniazid, rifampicin, pyrazinamide, and ethambutol, which has been used either as Fix-Dose Combination ( ...
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47 Evaluation of Hepatotoxicity of Anti-Tuberculosis Regimens
https://pdfs.semanticscholar.org/48a3/a0f02249e92918bbdad05a31ceec4bccb9b3.pdf
anti TB drug induced hepatotoxicity was higher in younger patients.10 ... incidence of hepatotoxicity after anti-tubercular treatment and to evaluate.
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48 Association of GST null genotypes with anti-tuberculosis drug ...
https://www.elsevier.es/en-revista-annals-hepatology-16-articulo-association-gst-null-genotypes-with-S166526811931302X
Background. The first line anti-tubercular (anti-TB) treatment normally involves isoniazid, rifampicin, pyrazinamide, and ethambutol.
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49 Antituberculous Drug-Induced Hepatitis in a Patient ... - Cureus
https://www.cureus.com/articles/97605-antituberculous-drug-induced-hepatitis-in-a-patient-with-congenital-adrenal-hyperplasia-a-clinical-challenge
The American Thoracic Society recommends restarting treatment in such patients without PZA with a regimen including INH, RIF, and EMB for nine ...
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50 Hepatotoxicity with Antituberculosis Drugs: The risk factors
https://pjms.com.pk/issues/janmar07/article/article4.html
Fifteen to 20 percent of patients receiving Isoniazid as a single agent for prophylaxis against tuberculosis may have increased serum alanine and aspartate ...
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51 GSTT1/GSTM1 Genotype and Anti-Tuberculosis Drug-Induced ...
https://www.mdpi.com/1422-0067/23/19/11028/pdf
anti-TB treatment, we genotyped by revealing the presence or absence of 215- and ... Keywords: tuberculosis; GSTT1; GSTM1; hepatotoxicity.
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52 Acute and Fatal Isoniazid-Induced Hepatotoxicity - Hindawi
https://www.hindawi.com/journals/criid/2016/3617408/
American Thoracic Society, “Preventive treatment in tuberculosis: a statement by the committee on therapy,” The American Review of Respiratory Disease, vol. · H.
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53 A prospective study of antituberculous drug-induced ...
https://link.springer.com/article/10.1007/s12072-008-9085-y
Despite the efficacy of anti-TB agents, hepatotoxicity from first-line drugs—isoniazid (INH), rifampin (RIF), and pyrazinamide (PZA)—may result ...
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54 Management of suspected drug-induced rash, kidney injury ...
http://www.mic.uct.ac.za/sites/default/files/image_tool/images/51/ADE%20Booklet_July2020_final171120.pdf
liver injury in adult patients on TB treatment and/or antiretroviral treatment. July 2020 ... Approximately half of patients presenting with hepatitis.
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55 Anti-tuberculosis drug induced hepatotoxicity: a study from ...
https://www.msjonline.org/index.php/ijrms/article/download/10550/7029
One of the adverse effects affecting TB treatment outcome is anti-TB drug induced hepatotoxicity (DIH). Therefore,.
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56 IJBCP International Journal of Basic & Clinical Pharmacology
https://www.ijbcp.com/index.php/ijbcp/article/download/753/684
ANTI TUBERCULAR DRUGS AND. HEPATOTOXICITY. The major drugs referred to as the first line regimen in treating TB include isoniazid, rifampicin, ethambutol,.
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57 Hepatotoxicity of antituberculosis drugs in a mother and a ...
https://www.biochemia-medica.com/en/journal/18/1/10.11613/BM.2008.011
To monitor the hepatotoxicity of these antituberculosis drugs, ... The major medication in tuberculosis therapy and prophylaxis is isoniazide.
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58 A Severe Hepatotoxicity by Antituberculosis Drug, and its ...
https://www.jkom.org/upload/jkm-37-2-119.pdf
antituberculosis treatment for her intestinal tuberculosis, whom traditional Korean medicine ... of acute hepatitis and is the most common cause of.
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59 Hepatotoxicity due to first-line anti-tuberculosis drugs: a five
https://www.ingentaconnect.com/content/10.5588/ijtld.12.0782
Hepatotoxicity during anti-tuberculosis treatment was defined by symptomatic elevation of liver transaminases ≥3 times the upper limit of ...
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60 International Journal of Infectious Diseases
https://www.ijidonline.com/article/S1201-9712(20)30504-X/pdf
Increased risk of hepatotoxicity and temporary drug withdrawal during treatment of active tuberculosis in pregnant women.
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61 Case Report on Anti-Tubercular Drug Induced Hepatoxicity ...
https://ijopp.org/sites/default/files/InJPharPract-14-4-294_0.pdf
Keywords: Hepatitis, Adverse drug reaction of anti-TB drug, Treatment, Pulmonary Koch infection, ALT, AST, Modified att. INTRODUCTION. Tuberculosis is a ...
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62 Reintroduction of anti-tuberculosis therapy following drug ...
https://www.fundingawards.nihr.ac.uk/award/NIHR129515
An observational cohort study of adults treated for latent TB infection (LTBI) ... research_call=19/07 Anti-tuberculosis drug hepatotoxicity and treatment ...
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63 Medical Update Webinar - Global Tuberculosis Institute
https://globaltb.njms.rutgers.edu/educationalmaterials/aa/Handouts/Treatment%20of%20TB%20-%20Managing%20Adverse%20Drug%20Effects.pdf
Hepatotoxicity. • Common complaints during TB treatment. • Relative frequency for different drugs: pyrazinamide > isoniazid > rifampin &.
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64 Rifampin Hepatotoxicity Associated With Treatment of Latent ...
https://www.amjmedsci.com/article/S0002-9629(15)31990-X/pdf
Abstract: Background: To determine the occurrence of hepatotoxicity associated with rifampin treatment of latent tuberculosis infection in.
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65 The role of hepatitis B infection in anti-tuberculosis drug ...
https://www.cambridge.org/core/journals/epidemiology-and-infection/article/role-of-hepatitis-b-infection-in-antituberculosis-druginduced-liver-injury-a-metaanalysis-of-cohort-studies/3FB6F024D82679FAFBFCC98DBBFAA663
Drug-induced liver injury (DILI) is a common adverse drug reaction leading to the interruption of tuberculosis (TB) therapy.
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66 Incidence and characteristics of antituberculosis drug-induced ...
https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/599
O'Brien RJ, Long MW, Cross FS, Lyle MA, Snider DE. Hepatotoxicity from isoniazid and rifampin among children treated for tuberculosis. Pediatrics. 1983;72:491-9 ...
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67 Hepatotoxicity during treatment for multidrug-resistant ...
https://www.researchgate.net/publication/221696290_Hepatotoxicity_during_treatment_for_multidrug-resistant_tuberculosis_Occurrence_management_and_outcome
The incidence of drug-induced liver injury in patients undergoing treatment for multidrug-resistant tuberculosis is 16.5% [1] ; thus, the side ...
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68 How to prevent liver damage induced by anti-t - EurekAlert!
https://www.eurekalert.org/news-releases/609634
Preventive therapy of contacts causes severe hepatotoxicity more often than curative treatment of clinical tuberculosis.
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69 Incidence of antituberculosis-drug-induced hepatotoxicity and ...
https://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=1;spage=14;epage=20;aulast=Abera
New cases of TB-infected individuals are treated by a combination of four drugs: isoniazid (INH), rifampin (RIF), pyrazinamide (PZA), and ...
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70 Risk factors for hepatotoxicity in patients hospitalized for ...
https://www.ejgm.co.uk/download/risk-factors-for-hepatotoxicity-in-patients-hospitalized-for-tuberculosis-7363.pdf
Introduction: Combination therapy with four drugs (isoniazid, rifampicin, pyrazinamid and ethambutol) is the treatment of choice in tuberculosis but ...
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71 the study of drug induced hepatotoxicity in att patients ...
https://www.nepjol.info/index.php/SAARCTB/article/view/3053/2652
The drug-induced hepatotoxicity is a significantly increasing problem worldwide, but it is of more concern in the treatment of tuberculosis (TB) infection, ...
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72 Guidance on Treating Latent TB Infection (LTBI) in Oregon
https://www.oregon.gov/oha/PH/DISEASESCONDITIONS/COMMUNICABLEDISEASE/TUBERCULOSIS/Documents/tools/GuidanceonTreatmentofLTBIinOregon.pdf
Prior side effects with LTBI treatment. • History of hepatitis or liver disease. • If symptomatic for acute hepatitis (jaundice, abdominal pain/bloating, ...
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73 Hepatotoxicity during Treatment for Tuberculosis in People ...
http://bibliobase.sermais.pt:8008/BiblioNET/Upload/PDF23/018599%20PLOS%20ONE%2011%206%2022%20jun%202016%20e.0157725.PDF
monitored during the first 60 days of tuberculosis treatment in Pernambuco, ... on hepatotoxicity during TB treatment in PLWHA have been ...
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74 Risk Factors and Pattern of Changes in Liver Enzymes Among ...
https://brieflands.com/articles/iji-14720.html
Risk factors of hepatotoxicity progression due to anti-tuberculosis (anti-TB) treatment include chronic liver disease, active alcohol use, ...
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75 Profilactic usage of N-acetyl cysteine in the treatment of ...
https://jag.journalagent.com/zkmj/pdfs/ZKMJ-60352-CASE_REPORT-YETMIS.pdf
Keywords: Children, hepatotoxicity, n-acetyl cysteine, treatment, tuberculosis. Received: July 11, 2021 Accepted: October 05, 2021 Online: November 01, 2021.
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76 Management of drug-induced liver injury in HIV-positive ...
https://sajhivmed.org.za/index.php/hivmed/article/view/63/93
In the case of confirmed moderate or severe drug-induced hepatotoxicity, treatment should be interrupted and re-introduced after hepatotoxicity has resolved.
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77 Chapter 5 - Canadian Tuberculosis Standards
https://www.canada.ca/content/dam/phac-aspc/migration/phac-aspc/tbpc-latb/pubs/tb-canada-7/assets/pdf/tb-standards-tb-normes-ch5-eng.pdf
Treatment of Active TB in the Elderly (and Others at Moderate to High Risk of ... induced hepatotoxicity in patients treated for TB disease.25,26 Therefore, ...
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78 HALT-TB Toxicity Management Guide for Adults Taking ...
https://thomas-nicholson-c95h.squarespace.com/s/Toxicity-Management-Guide-030620.pdf
Flow diagram of hepatotoxicity testing and management for patients receiving treatment for latent tuberculosis infection. Abbreviations: B6, pyridoxine; BMI ...
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79 Coincidence of drug induced liver injury and cholecystitis on ...
https://www.ijmedicine.com/index.php/ijam/article/download/3441/2320
tuberculosis treatment such as hepatotoxicity, skin ... TB treatment regimens such as a combination of isoniazid,.
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80 Case Reports on Severe Antituberculosis-Drug Induced ...
https://journal.unhas.ac.id/index.php/jmednus/article/view/13450/6687
Induced Hepatotoxicity in Tuberculosis Patients: The Post-Incidence Therapy ... intensive phase of anti-tuberculosis treatment focusing on.
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81 ANTI TUBERCULAR DRUGS INDUCED HEPATOTOXICITY ...
https://innovareacademics.in/journals/index.php/ijpps/article/download/40704/24654
The management therapy for TB patients with anti-TB DIH is imperative to ensure successful TB treatment and not recurrence DIH. Aim of the ...
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82 summary of rifampin (rif) for treatment of latent tb infection (ltbi)
https://doh.sd.gov/documents/diseases/infectious/TB/HS437.pdf
Clinical evaluations during LTBI treatment should assess for; adverse drug reactions, especially hepatotoxicity, adherence to therapy, signs and symptoms ...
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83 Effectiveness of hepatoprotective drugs for anti-tuberculosis ...
https://d-nb.info/1120871549/34
Background: The effectiveness of hepatoprotective drugs for DIH (drug induced hepatotoxicity) during tuberculosis treatment is not clear. We evaluated the ...
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84 Early detection of elevated liver function test in drug-resistant ...
https://balimedicaljournal.org/index.php/bmj/article/download/3113/2039/12907
Introduction: Tuberculosis (TB) treatment consists of more than one drug to achieve goal treatment. Hepatotoxicity is a.
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85 Hepatotoxicity In Anti-TB Treatment - OMICS International
https://www.omicsonline.org/mycobacterial-diseases/hepatotoxicity-in-anti-TB-treatment.php
ATDIH has been associated with three of the first line anti-TB drugs; rifampicin, isoniazid, and pyrazinamide and the risk of developing ATDIH is enhanced .
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86 Predicting Antituberculosis Drug–Induced Liver Injury Using ...
https://medinform.jmir.org/2021/7/e29226
Among various populations, the incidence of TB-DILI ranges from 2.3% to 27.7% during anti-TB therapy [ ...
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87 Acute Liver Failure | Antitubercular Therapy | Hepatotoxicity
https://www.ijpsonline.com/articles/att-a-double-edged-sword.html?view=mobile
Co-infection with HBV in those on anti- TB medicines makes the condition more critical and they are noted to have a higher incidence of liver damage with an ...
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88 Tuberculosis Drug-Induced Liver Injury
https://www.currytbcenter.ucsf.edu/trainings/tuberculosis-drug-induced-liver-injury
Identify TB patients who from the start of therapy are candidates for either liver-sparing regimens or close monitoring of hepatic function. CME ...
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89 Tuberculosis Drug-Induced Liver Injury Webinar - YouTube
https://www.youtube.com/watch?v=gzAJ8qYwRBw
CurryTBCenter
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90 Isoniazid - Wikipedia
https://en.wikipedia.org/wiki/Isoniazid
Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis. ... For active tuberculosis it is often used ...
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91 Saturday, April 23, 2022 - Research SOP
https://www.researchsop.com/2022/04/evaluation-of-hepatoprotective-activity-of-herbal-formulations-using-anti-tuberclosis%20drug-rifampicin-isoniazide-and-pyrazinamide-induced-hepatotoxicity-in-experimental-animals.html
Tuberculosis (TB) is one of the major communicable diseases. Isoniazid (INH) and rifampicin (RIF) are the two major regimens currently used for ...
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92 Liver function tests - Mayo Clinic
https://www.mayoclinic.org/tests-procedures/liver-function-tests/about/pac-20394595
... such as hepatitis; Monitor the progression of a disease, such as viral or alcoholic hepatitis, and determine how well a treatment is ...
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93 Isoniazid - Mechanisms of Hepatotoxicity - LIVER Toxicity
https://livertoxicity.weebly.com/isoniazid.html
However, as they had never previously been treated with Streptomycin, which was the main TB treatment at the time, this allowed for an accurate trial on the ...
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94 Side Effects of Drugs Annual: A worldwide yearly survey of ...
https://books.google.com/books?id=iCqiBQAAQBAJ&pg=PA354&lpg=PA354&dq=hepatotoxicity+tb+treatment&source=bl&ots=aqPuuTPC6B&sig=ACfU3U08Gd3moGIQJxS9iC2mMSvNq5UfzQ&hl=en&sa=X&ved=2ahUKEwjLrJ2Iv8b7AhUImIkEHehwDvAQ6AF6BAgkEAM
Hepatotoxicity INH is extensively metabolized in the liver and is ... where 1.02% of the INH-treated TB patients developed hepatotoxicity when single daily ...
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95 Anti-Infective Medication Therapy, Antitubercular Agents
https://search.alexanderstreet.com/view/work/bibliographic_entity%7Cvideo_work%7C3370379/anti-infective-medication-therapy-antitubercular-agents-tuberculosis-treatment
Rifampin also referred to as RMP is the second major anti tuberculosis agent. It is also metabolized in the liver and can be toxic to this organ. So it has the ...
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96 Reducing the burden of tuberculosis treatment | MIT News
https://news.mit.edu/2019/stomach-device-antibiotics-tuberculosis-0313
One reason TB is so pervasive is that treatment requires a six-month ... Another disease where this approach could be useful is hepatitis C, ...
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