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Google Keyword Rankings for : emt hdac inhibitor
1
HDAC inhibitors induce epithelial-mesenchymal transition in ...
https://pubmed.ncbi.nlm.nih.gov/25813246/
Increased iron accumulation following HDAC inhibitor mediated EMT is associated with decreased expression of the iron export protein ferroportin, enhanced ROS ...
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https://pubmed.ncbi.nlm.nih.gov/25813246/
Increased iron accumulation following HDAC inhibitor mediated EMT is associated with decreased expression of the iron export protein ferroportin, enhanced ROS ...
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2
An epithelial marker promoter induction screen ... - Nature
https://www.nature.com/articles/cddiscovery201641
We demonstrate that these HDAC inhibitors (HDACi) induce different effects in ovarian cancer cells with different EMT statuses.
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https://www.nature.com/articles/cddiscovery201641
We demonstrate that these HDAC inhibitors (HDACi) induce different effects in ovarian cancer cells with different EMT statuses.
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3
HDAC2 inhibits EMT-mediated cancer metastasis by ...
https://jeccr.biomedcentral.com/articles/10.1186/s13046-020-01783-9
HDAC inhibitors (HDACis) have been developed as potential anticancer agents, and can restore the expression and function of tumor suppressors [8] ...
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https://jeccr.biomedcentral.com/articles/10.1186/s13046-020-01783-9
HDAC inhibitors (HDACis) have been developed as potential anticancer agents, and can restore the expression and function of tumor suppressors [8] ...
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4
HDAC inhibitors induce epithelial ... - Spandidos Publications
https://www.spandidos-publications.com/10.3892/or.2015.3879
We investigated the EMT phenotype in four colon cancer cell lines when challenged with HDAC inhibitors trichostatin A (TSA) and valproic acid ( ...
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https://www.spandidos-publications.com/10.3892/or.2015.3879
We investigated the EMT phenotype in four colon cancer cell lines when challenged with HDAC inhibitors trichostatin A (TSA) and valproic acid ( ...
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5
A Histone Deacetylase Inhibitor Suppresses Epithelial ... - PLOS
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145985
Moreover, the HDAC activity was increased by exposure to TGF-β1. These findings suggest that HDACs could be associated with EMT, and inhibition ...
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145985
Moreover, the HDAC activity was increased by exposure to TGF-β1. These findings suggest that HDACs could be associated with EMT, and inhibition ...
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6
HDAC inhibitors may regulate EMT and surfactant protein C in ...
https://erj.ersjournals.com/content/46/suppl_59/PA939
We investigated to see whether inhibition of histone deacetylases (HDAC) could reverse epithelial to mesenchymal (EMT) like intermediate phenotype during ...
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https://erj.ersjournals.com/content/46/suppl_59/PA939
We investigated to see whether inhibition of histone deacetylases (HDAC) could reverse epithelial to mesenchymal (EMT) like intermediate phenotype during ...
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7
HDAC inhibition reverses EMT through modulation of ZEB1
https://aacrjournals.org/cancerres/article/72/8_Supplement/2593/579396/Abstract-2593-HDAC-inhibition-reverses-EMT-through
Histone deacetylase (HDAC) inhibition is known to inhibit the Epithelial-to-Mesenchymal Transition (EMT) in various cancer models by ...
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https://aacrjournals.org/cancerres/article/72/8_Supplement/2593/579396/Abstract-2593-HDAC-inhibition-reverses-EMT-through
Histone deacetylase (HDAC) inhibition is known to inhibit the Epithelial-to-Mesenchymal Transition (EMT) in various cancer models by ...
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8
Cancers | Free Full-Text | Histone Deacetylase Inhibitors and ...
https://www.mdpi.com/2072-6694/11/2/148/htm
Epithelial-mesenchymal transition (EMT) is a biological reversible process in which cells undergo multiple biochemical changes—lose their epithelial properties, ...
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https://www.mdpi.com/2072-6694/11/2/148/htm
Epithelial-mesenchymal transition (EMT) is a biological reversible process in which cells undergo multiple biochemical changes—lose their epithelial properties, ...
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9
Effect of histone deacetylase inhibitor on epithelial ...
https://www.researchgate.net/publication/324118794_Effect_of_histone_deacetylase_inhibitor_on_epithelial-mesenchymal_transition_of_liver_fibrosis_EFFECT_OF_HDAC_INHIBITOR_ON_EMT
Effect of histone deacetylase inhibitor on epithelial-mesenchymal transition of liver fibrosis: EFFECT OF HDAC INHIBITOR ON EMT.
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https://www.researchgate.net/publication/324118794_Effect_of_histone_deacetylase_inhibitor_on_epithelial-mesenchymal_transition_of_liver_fibrosis_EFFECT_OF_HDAC_INHIBITOR_ON_EMT
Effect of histone deacetylase inhibitor on epithelial-mesenchymal transition of liver fibrosis: EFFECT OF HDAC INHIBITOR ON EMT.
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10
ZEB1‐associated drug resistance in cancer cells is reversed ...
https://www.embopress.org/doi/10.15252/emmm.201404396
Identification of the class I HDAC inhibitor mocetinostat as drug to interfere ... The EMT inducer ZEB1 is a transcriptional repressor of epithelial genes, ...
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https://www.embopress.org/doi/10.15252/emmm.201404396
Identification of the class I HDAC inhibitor mocetinostat as drug to interfere ... The EMT inducer ZEB1 is a transcriptional repressor of epithelial genes, ...
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11
Inhibition of Histone Deacetylase Activity Suppresses ...
https://jasn.asnjournals.org/content/18/1/58
It was shown that trichostatin A (TSA), an HDAC inhibitor, prevented TGF-β1–induced EMT in cultured human renal proximal tubular epithelial cells.
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https://jasn.asnjournals.org/content/18/1/58
It was shown that trichostatin A (TSA), an HDAC inhibitor, prevented TGF-β1–induced EMT in cultured human renal proximal tubular epithelial cells.
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12
Targeting histone deacetylase-3 blocked epithelial ...
https://link.springer.com/article/10.1007/s10565-021-09673-2
Histone deacetylase (HDAC) inhibitors (HDIs) can modulate the epithelial-mesenchymal transition (EMT) progression and inhibit the migration ...
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https://link.springer.com/article/10.1007/s10565-021-09673-2
Histone deacetylase (HDAC) inhibitors (HDIs) can modulate the epithelial-mesenchymal transition (EMT) progression and inhibit the migration ...
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13
Histone deacetylases, Mbd3/NuRD, and Tet2 hydroxylase are ...
https://par.nsf.gov/servlets/purl/10233655
An epithelial–mesenchymal transition (EMT) represents a basic morphogenetic ... The inhibition of HDAC activity has been implicated in.
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https://par.nsf.gov/servlets/purl/10233655
An epithelial–mesenchymal transition (EMT) represents a basic morphogenetic ... The inhibition of HDAC activity has been implicated in.
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14
Trichostatin A inhibits radiation-induced epithelial-to ...
https://www.oncotarget.com/article/21664/text/
HDAC inhibitors are a new family of anti-cancer agents currently being used ... TSA reversed EMT in irradiated rat alveolar epithelial cells ...
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https://www.oncotarget.com/article/21664/text/
HDAC inhibitors are a new family of anti-cancer agents currently being used ... TSA reversed EMT in irradiated rat alveolar epithelial cells ...
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15
Histone Deacetylase Inhibitors Trichostatin A and Vorinostat ...
https://iovs.arvojournals.org/article.aspx?articleid=2128399
Transforming growth factor β2–induced EMT was suppressed by TSA and SAHA. Histone deacetylase inhibition in pig lens epithelia led to increased acetylation ...
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https://iovs.arvojournals.org/article.aspx?articleid=2128399
Transforming growth factor β2–induced EMT was suppressed by TSA and SAHA. Histone deacetylase inhibition in pig lens epithelia led to increased acetylation ...
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16
ZEB1 throttles therapeutic target, protecting KRAS-mutant lung ...
https://www.mdanderson.org/newsroom/zeb1-throttles-therapeutic-target-protecting-kras-mutant-lung-cancer.h00-159301467.html
Previous research by other labs had shown that a type of drug called a histone deacetylase (HDAC) inhibitor can reverse EMT, ...
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https://www.mdanderson.org/newsroom/zeb1-throttles-therapeutic-target-protecting-kras-mutant-lung-cancer.h00-159301467.html
Previous research by other labs had shown that a type of drug called a histone deacetylase (HDAC) inhibitor can reverse EMT, ...
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17
A Histone Deacetylase Inhibitor Suppresses ... - Figshare
https://figshare.com/articles/dataset/_A_Histone_Deacetylase_Inhibitor_Suppresses_Epithelial_Mesenchymal_Transition_and_Attenuates_Chemoresistance_in_Biliary_Tract_Cancer_/1632490
Epithelial-mesenchymal transition (EMT) is involved in the characteristics of malignancy, such as invasion, metastasis, and chemoresistance.
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https://figshare.com/articles/dataset/_A_Histone_Deacetylase_Inhibitor_Suppresses_Epithelial_Mesenchymal_Transition_and_Attenuates_Chemoresistance_in_Biliary_Tract_Cancer_/1632490
Epithelial-mesenchymal transition (EMT) is involved in the characteristics of malignancy, such as invasion, metastasis, and chemoresistance.
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18
HDAC inhibitors induce epithelial-mesenchymal ... - ProQuest
https://search.proquest.com/openview/25fd9616820abd653f6a62474e39a7bc/1?pq-origsite=gscholar&cbl=2044953
We investigated the EMT phenotype in four colon cancer cell lines when challenged with HDAC inhibitors trichostatin A (TSA) and valproic acid (VPA) with or ...
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https://search.proquest.com/openview/25fd9616820abd653f6a62474e39a7bc/1?pq-origsite=gscholar&cbl=2044953
We investigated the EMT phenotype in four colon cancer cell lines when challenged with HDAC inhibitors trichostatin A (TSA) and valproic acid (VPA) with or ...
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19
Epithelial-Mesenchymal Transition (EMT) as a Therapeutic ...
https://www.karger.com/Article/Fulltext/512218
However, while the inhibition of HDACs could repress EMT and tumour growth in some models, other models showed the opposite with an induction of EMT-TF ...
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https://www.karger.com/Article/Fulltext/512218
However, while the inhibition of HDACs could repress EMT and tumour growth in some models, other models showed the opposite with an induction of EMT-TF ...
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20
Identifying Novel Inhibitors of Epithelial to Mesenchymal ...
https://kuscholarworks.ku.edu/handle/1808/21926?show=full
Next, we investigated novel derivatives of the histone deacetylase (HDAC) inhibitors SAHA and MS-275, which are known EMT inhibitors.
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https://kuscholarworks.ku.edu/handle/1808/21926?show=full
Next, we investigated novel derivatives of the histone deacetylase (HDAC) inhibitors SAHA and MS-275, which are known EMT inhibitors.
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21
HDAC2 inhibits EMT-mediated cancer metastasis by ...
https://d-nb.info/1224859871/34
HDAC inhibitors (HDACis) have been developed as potential anticancer agents, and can restore the expression and function of tumor sup- pressors [8]. However, ...
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https://d-nb.info/1224859871/34
HDAC inhibitors (HDACis) have been developed as potential anticancer agents, and can restore the expression and function of tumor sup- pressors [8]. However, ...
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22
An Attractive Therapeutic Strategy Against Breast Cancer
https://ar.iiarjournals.org/content/37/1/35
Histone Deacetylase Inhibitors: An Attractive Therapeutic Strategy Against Breast ... Given the fact that HDAC inhibitors are related to EMT and TICs, ...
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https://ar.iiarjournals.org/content/37/1/35
Histone Deacetylase Inhibitors: An Attractive Therapeutic Strategy Against Breast ... Given the fact that HDAC inhibitors are related to EMT and TICs, ...
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23
Histone deacetylase inhibitors promote epithelial ...
https://thno.org/v10p10245.htm
Results: Our study provided novel mechanistic insights into HDI-induced EMT mediated by the autophagy AMPK-FOXO1-ULK1-Snail signaling axis. We demonstrated that ...
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https://thno.org/v10p10245.htm
Results: Our study provided novel mechanistic insights into HDI-induced EMT mediated by the autophagy AMPK-FOXO1-ULK1-Snail signaling axis. We demonstrated that ...
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24
Histone deacetylase inhibitor valproic acid (VPA) promotes ...
https://www.tandfonline.com/doi/abs/10.1080/19336918.2015.1112486
Histone deacetylase inhibitors (HDACIs) have been shown to have ... that VPA can trigger the epithelial–mesenchymal transition (EMT) of CRC cells.
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https://www.tandfonline.com/doi/abs/10.1080/19336918.2015.1112486
Histone deacetylase inhibitors (HDACIs) have been shown to have ... that VPA can trigger the epithelial–mesenchymal transition (EMT) of CRC cells.
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25
MA07.10 HDAC Inhibition Overcomes Crizotinib-Resistance ...
https://www.jto.org/article/S1556-0864(16)31673-2/fulltext
While epithelial–mesenchymal transition (EMT) was recently reported to be associated with resistance to crizotinib in EML4-ALK lung cancer cells in vitro, the ...
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https://www.jto.org/article/S1556-0864(16)31673-2/fulltext
While epithelial–mesenchymal transition (EMT) was recently reported to be associated with resistance to crizotinib in EML4-ALK lung cancer cells in vitro, the ...
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26
HDAC Inhibition Induces Cell Cycle Arrest and Mesenchymal ...
https://www.por-journal.com/articles/10.3389/pore.2021.636088/full
This morphology can be attributed to epithelial-mesenchymal transition (EMT) that often associates with tumor invasion and metastasis.
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https://www.por-journal.com/articles/10.3389/pore.2021.636088/full
This morphology can be attributed to epithelial-mesenchymal transition (EMT) that often associates with tumor invasion and metastasis.
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27
Contribution of Soluble Factors to EMT
https://www.cellsignal.com/pathways/contribution-soluble-factors-emt
The TGF-β signaling pathway is strongly implicated in the process of EMT induction, ... where it displaces the Groucho/HDAC inhibition complex to activate ...
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https://www.cellsignal.com/pathways/contribution-soluble-factors-emt
The TGF-β signaling pathway is strongly implicated in the process of EMT induction, ... where it displaces the Groucho/HDAC inhibition complex to activate ...
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28
Article - Dynamic Chromatin Modification Sustains Epithelial ...
https://www.cell.com/cell-reports/pdf/S2211-1247(13)00718-3.pdf
epithelial-to-mesenchymal transition (EMT) is essential for the ... EMT, whereas HDAC inhibitors (e.g., TSA) can inhibit both the.
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https://www.cell.com/cell-reports/pdf/S2211-1247(13)00718-3.pdf
epithelial-to-mesenchymal transition (EMT) is essential for the ... EMT, whereas HDAC inhibitors (e.g., TSA) can inhibit both the.
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29
Contextual extracellular cues promote tumor cell EMT and ...
http://genesdev.cshlp.org/content/23/18/2140.short
HDAC Inhibitors Enhance T-Cell Chemokine Expression and Augment Response to PD-1 Immunotherapy in Lung Adenocarcinoma Clin. Cancer Res.
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http://genesdev.cshlp.org/content/23/18/2140.short
HDAC Inhibitors Enhance T-Cell Chemokine Expression and Augment Response to PD-1 Immunotherapy in Lung Adenocarcinoma Clin. Cancer Res.
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30
NAVER Academic > 담관암 세포주에서 HDAC 억제제에 의한 ...
https://academic.naver.com/article.naver?doc_id=79169396
... 세포주에서 HDAC 억제제에 의한 EMT 억제 : Suppression of Epithelial-Mesenchymal Transition in Human Cholangiocarcinoma Cell Lines by the HDAC Inhibitors.
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https://academic.naver.com/article.naver?doc_id=79169396
... 세포주에서 HDAC 억제제에 의한 EMT 억제 : Suppression of Epithelial-Mesenchymal Transition in Human Cholangiocarcinoma Cell Lines by the HDAC Inhibitors.
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31
Tackle Epithelial-Mesenchymal Transition with ... - UKnowledge
https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1108&context=pharmacol_facpub
Epigenetic drugs are illustrated to inhibit EMT including histone deacetylase (HDAC) inhibitor, histone acetylase inhibitor, acetylation reader ...
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https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1108&context=pharmacol_facpub
Epigenetic drugs are illustrated to inhibit EMT including histone deacetylase (HDAC) inhibitor, histone acetylase inhibitor, acetylation reader ...
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32
Histone deacetylase 9 promotes endothelial-mesenchymal ...
https://www.jci.org/articles/view/131178
Aberrant HDAC expression and activity can promote EMT and cancer metastasis, while HDAC inhibitors can prevent EMT (25–27).
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https://www.jci.org/articles/view/131178
Aberrant HDAC expression and activity can promote EMT and cancer metastasis, while HDAC inhibitors can prevent EMT (25–27).
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33
Proteomic Analysis of Epithelial to Mesenchymal Transition ...
https://www.mcponline.org/article/S1535-9476(20)33650-1/pdf
Epithelial to mesenchymal transition (EMT) is a process by which epithelial cells acquire a ... HDAC Inhibition—MCF7 cells were incubated with 0.5–10 μg of.
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https://www.mcponline.org/article/S1535-9476(20)33650-1/pdf
Epithelial to mesenchymal transition (EMT) is a process by which epithelial cells acquire a ... HDAC Inhibition—MCF7 cells were incubated with 0.5–10 μg of.
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34
LSD1 Impairs the Epithelial-Mesenchymal ... - ASH Publications
https://ashpublications.org/blood/article/124/21/3410/97486/LSD1-Impairs-the-Epithelial-Mesenchymal-Transition
... Transition (EMT) and Osteoclastogenesis Potency in Multiple Myeloma and Synergistically Induces Cytotoxicity with HDAC Inhibitors.
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https://ashpublications.org/blood/article/124/21/3410/97486/LSD1-Impairs-the-Epithelial-Mesenchymal-Transition
... Transition (EMT) and Osteoclastogenesis Potency in Multiple Myeloma and Synergistically Induces Cytotoxicity with HDAC Inhibitors.
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35
Histone deacetylase-2 is a key regulator of diabetes
https://journals.physiology.org/doi/full/10.1152/ajprenal.00086.2009
This study examined the effect of HDAC inhibition on renal fibrosis induced by ... and EMT by a nonselective HDAC inhibitor in STZ-induced diabetic kidneys.
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https://journals.physiology.org/doi/full/10.1152/ajprenal.00086.2009
This study examined the effect of HDAC inhibition on renal fibrosis induced by ... and EMT by a nonselective HDAC inhibitor in STZ-induced diabetic kidneys.
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36
ZEB1 Mediates Drug Resistance and EMT in p300-Deficient ...
https://www.jcancer.org/v08p1453.htm
Wnt signaling and histone deacetylase inhibitors. The histone deacetylase inhibitor (HDACi) butyrate, derived from dietary fiber, exerts a strong preventive ...
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https://www.jcancer.org/v08p1453.htm
Wnt signaling and histone deacetylase inhibitors. The histone deacetylase inhibitor (HDACi) butyrate, derived from dietary fiber, exerts a strong preventive ...
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37
LSD1 Impairs the Epithelial-Mesenchymal Transition (EMT ...
https://scholar.harvard.edu/samur/publications/lsd1-impairs-epithelial-mesenchymal-transition-emt-and-osteoclastogenesis-potency
... Transition (EMT) and Osteoclastogenesis Potency in Multiple Myeloma and Synergistically Induces Cytotoxicity with HDAC Inhibitors.
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https://scholar.harvard.edu/samur/publications/lsd1-impairs-epithelial-mesenchymal-transition-emt-and-osteoclastogenesis-potency
... Transition (EMT) and Osteoclastogenesis Potency in Multiple Myeloma and Synergistically Induces Cytotoxicity with HDAC Inhibitors.
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38
Tackle Epithelial-Mesenchymal Transition With Epigenetic ...
https://www.readcube.com/articles/10.3389/fphar.2020.596239
Tumor-associated EMT contributes to cancer cell initiation, invasion, metastasis, drug resistance ... However, HDAC inhibitors modulate EMT-related factors
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https://www.readcube.com/articles/10.3389/fphar.2020.596239
Tumor-associated EMT contributes to cancer cell initiation, invasion, metastasis, drug resistance ... However, HDAC inhibitors modulate EMT-related factors
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39
SAHA modulates cell proliferation, colony forming ... - De Gruyter
https://www.degruyter.com/document/doi/10.1515/tjb-2018-0029/html?lang=en
EMT is a biological process that allow a polarized epithelial cell ... Suberoylanilide hydroxamic acid (SAHA) is a known HDAC inhibitor that ...
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https://www.degruyter.com/document/doi/10.1515/tjb-2018-0029/html?lang=en
EMT is a biological process that allow a polarized epithelial cell ... Suberoylanilide hydroxamic acid (SAHA) is a known HDAC inhibitor that ...
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40
(PDF) Short-term stimulation with histone deacetylase inhibitor ...
https://typeset.io/papers/short-term-stimulation-with-histone-deacetylase-inhibitor-2rep90idy7
Epithelial-mesenchymal transition (EMT) may be one of the reasons for the failure in some clinical trials regarding histone deacetylase inhibitors ...
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https://typeset.io/papers/short-term-stimulation-with-histone-deacetylase-inhibitor-2rep90idy7
Epithelial-mesenchymal transition (EMT) may be one of the reasons for the failure in some clinical trials regarding histone deacetylase inhibitors ...
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41
Targeting epithelial-mesenchymal transition - an ongoing wild ...
https://jcmtjournal.com/article/view/3624
Epithelial-mesenchymal transition (EMT) is a natural phenomenon ... It also identified a novel HDAC inhibitor 1-(benzylsulfonyl) indoline among 17 other ...
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https://jcmtjournal.com/article/view/3624
Epithelial-mesenchymal transition (EMT) is a natural phenomenon ... It also identified a novel HDAC inhibitor 1-(benzylsulfonyl) indoline among 17 other ...
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42
The role of epithelial to mesenchymal transition in resistance ...
https://tlcr.amegroups.com/article/view/7332/6833
The knowledge on EGFR-directed tyrosine kinase inhibitors (TKIs) and their ... Two such EMT targeting drug-types under investigation are HDAC inhibitors ...
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https://tlcr.amegroups.com/article/view/7332/6833
The knowledge on EGFR-directed tyrosine kinase inhibitors (TKIs) and their ... Two such EMT targeting drug-types under investigation are HDAC inhibitors ...
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43
PIIS2352-3964(21)00250-4.pdf - The Lancet
https://www.thelancet.com/pdfs/journals/ebiom/PIIS2352-3964(21)00250-4.pdf
signatures to HDAC inhibitors and identifies Dasatinib as a synergistic interactor in small-cell lung cancer. Haitang Yang, MD-PhDa,1, ...
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https://www.thelancet.com/pdfs/journals/ebiom/PIIS2352-3964(21)00250-4.pdf
signatures to HDAC inhibitors and identifies Dasatinib as a synergistic interactor in small-cell lung cancer. Haitang Yang, MD-PhDa,1, ...
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44
New Insights into the Implication of Epigenetic Alterations in ...
https://hal.archives-ouvertes.fr/hal-02349588/document
Alterations in the EMT of Triple Negative Breast ... histone deacetylase inhibitors (HDACis) have emerged as a promising new class of ...
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https://hal.archives-ouvertes.fr/hal-02349588/document
Alterations in the EMT of Triple Negative Breast ... histone deacetylase inhibitors (HDACis) have emerged as a promising new class of ...
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45
First-in-Class Dual Mechanism Ferroptosis-HDAC Inhibitor ...
https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01276
HDAC inhibitors are an attractive class of cytotoxic agents for the ... HDAC inhibition induces EMT and alters cellular iron homeostasis.
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https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01276
HDAC inhibitors are an attractive class of cytotoxic agents for the ... HDAC inhibition induces EMT and alters cellular iron homeostasis.
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46
Smoking induces epithelial-to-mesenchymal transition in non ...
https://www.vumc.org/massion-lab/publication/smoking-induces-epithelial-mesenchymal-transition-non-small-cell-lung-cancer-through
The histone deacetylase (HDAC) inhibitor MS-275 reverses CSC-induced EMT, migration, and invasion through the restoration of E-cadherin expression.
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https://www.vumc.org/massion-lab/publication/smoking-induces-epithelial-mesenchymal-transition-non-small-cell-lung-cancer-through
The histone deacetylase (HDAC) inhibitor MS-275 reverses CSC-induced EMT, migration, and invasion through the restoration of E-cadherin expression.
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47
Original Article Histone acetyltransferase inhibitor C646 ...
https://e-century.us/files/ijcep/8/3/ijcep0005651.pdf
ase (HAT) inhibitor, high glucose-induced EMT in HPMCs was counteracted. ... At present, several specific HDAC inhibitors are.
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https://e-century.us/files/ijcep/8/3/ijcep0005651.pdf
ase (HAT) inhibitor, high glucose-induced EMT in HPMCs was counteracted. ... At present, several specific HDAC inhibitors are.
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48
HDAC inhibitors as antifibrotic drugs in cardiac and pulmonary ...
https://journals.sagepub.com/doi/10.1177/2040622319862697
B. HDAC inhibitors target various processes in which HDACs are ... such as inflammation, epithelial to mesenchymal transition (EMT), ...
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https://journals.sagepub.com/doi/10.1177/2040622319862697
B. HDAC inhibitors target various processes in which HDACs are ... such as inflammation, epithelial to mesenchymal transition (EMT), ...
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49
An epithelial marker promoter induction screen ... - ScienceOpen
https://www.scienceopen.com/document_file/98369222-7ade-402f-85fd-4d0800372737/PubMedCentral/98369222-7ade-402f-85fd-4d0800372737.pdf
histone deacetylase inhibitors to restore epithelial ... a histone deacetylase inhibitor (HDACi), is identified to exert EMT reversal ...
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https://www.scienceopen.com/document_file/98369222-7ade-402f-85fd-4d0800372737/PubMedCentral/98369222-7ade-402f-85fd-4d0800372737.pdf
histone deacetylase inhibitors to restore epithelial ... a histone deacetylase inhibitor (HDACi), is identified to exert EMT reversal ...
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50
158363.pdf - CyberLeninka
https://cyberleninka.org/article/n/158363.pdf
Keywords: histone deacetylase inhibitor; lens epithelium cells (LECs); proliferation; epithelial–mesenchymal transition (EMT); anterior ...
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https://cyberleninka.org/article/n/158363.pdf
Keywords: histone deacetylase inhibitor; lens epithelium cells (LECs); proliferation; epithelial–mesenchymal transition (EMT); anterior ...
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51
HDAC Inhibitors: Novel Therapies in Combination with ...
https://biomedres.us/pdfs/BJSTR.MS.ID.006887.pdf
Keywords: HDAC Inhibitor; Melanoma; ... B-Cell Lymphoma; EMT: Epithelial Mesenchymal Transition; FDA: Food And Drug.
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https://biomedres.us/pdfs/BJSTR.MS.ID.006887.pdf
Keywords: HDAC Inhibitor; Melanoma; ... B-Cell Lymphoma; EMT: Epithelial Mesenchymal Transition; FDA: Food And Drug.
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52
Histone deacetylase inhibitors reinforce the phenotypical ...
https://www.dovepress.com/histone-deacetylase-inhibitors-reinforce-the-phenotypical-markers-of-b-peer-reviewed-fulltext-article-CMAR
Changes in the expression level of different cadherins, so-called cadherin switches, have been used to monitor the EMT process in development ...
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https://www.dovepress.com/histone-deacetylase-inhibitors-reinforce-the-phenotypical-markers-of-b-peer-reviewed-fulltext-article-CMAR
Changes in the expression level of different cadherins, so-called cadherin switches, have been used to monitor the EMT process in development ...
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53
HDAC inhibitors with potential to overcome drug resistance in ...
https://cdrjournal.com/article/view/4466
Histone deacetylases, HDAC inhibitors, castration-resistant prostate cancer, ... HDAC inhibitors also induced epithelial-to-mesenchymal transition (EMT) in ...
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https://cdrjournal.com/article/view/4466
Histone deacetylases, HDAC inhibitors, castration-resistant prostate cancer, ... HDAC inhibitors also induced epithelial-to-mesenchymal transition (EMT) in ...
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54
Epigenetic Regulation of EMT: The Snail Story - EurekaSelect
https://www.eurekaselect.com/article/54302
While the epithelial-mesenchymal transition (EMT) plays a fundamental role ... Briefly, recruitment of the LSD1/HDAC complex by Snail facilitates histone ...
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https://www.eurekaselect.com/article/54302
While the epithelial-mesenchymal transition (EMT) plays a fundamental role ... Briefly, recruitment of the LSD1/HDAC complex by Snail facilitates histone ...
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55
The HDAC inhibitor, vorinastat, prevents TGF-beta 1 induced ...
https://experts.mcmaster.ca/display/publication641960
The HDAC inhibitor, vorinastat, prevents TGF-beta 1 induced EMT and apoptosis in human renal proximal tubular cells Conference Paper uri icon.
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https://experts.mcmaster.ca/display/publication641960
The HDAC inhibitor, vorinastat, prevents TGF-beta 1 induced EMT and apoptosis in human renal proximal tubular cells Conference Paper uri icon.
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56
Histone deacetylase class-I inhibition promotes epithelial ...
https://academic.oup.com/nar/article/45/11/6334/3091652
Histone deacetylases (HDAC) are epigenetic. ... Consistent with the proposed importance of EMT in promoting tumor cell migration and ...
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https://academic.oup.com/nar/article/45/11/6334/3091652
Histone deacetylases (HDAC) are epigenetic. ... Consistent with the proposed importance of EMT in promoting tumor cell migration and ...
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57
A Histone Deacetylase Inhibitor Suppresses Epithelial ...
https://docksci.com/a-histone-deacetylase-inhibitor-suppresses-epithelial-mesenchymal-transition-and_5a222322d64ab2d827afa57a.html
Epithelial-mesenchymal transition (EMT) is involved in the characteristics of malignancy, such as invasion, metastasis, ...
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https://docksci.com/a-histone-deacetylase-inhibitor-suppresses-epithelial-mesenchymal-transition-and_5a222322d64ab2d827afa57a.html
Epithelial-mesenchymal transition (EMT) is involved in the characteristics of malignancy, such as invasion, metastasis, ...
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58
HDAC Inhibitor Review & List - Selleck Chemicals
https://www.selleckchem.com/HDAC.html
HDAC inhibitors (inhibiting targets of signaling pathways) used for various assays, some have entered clinical trials, which would be new cancer therapies.
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https://www.selleckchem.com/HDAC.html
HDAC inhibitors (inhibiting targets of signaling pathways) used for various assays, some have entered clinical trials, which would be new cancer therapies.
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59
Epithelial-mesenchymal Transition Reporter Cells - ATCC
https://www.atcc.org/cell-products/reporter-labeled-cells/epithelial-mesenchymal-transition-reporter-cells
Advanced models for real-time monitoring of EMT · Generation of a NSCLC EMT Reporter Cell Line for Metastatic Lung Cancer Drug Discovery and ...
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https://www.atcc.org/cell-products/reporter-labeled-cells/epithelial-mesenchymal-transition-reporter-cells
Advanced models for real-time monitoring of EMT · Generation of a NSCLC EMT Reporter Cell Line for Metastatic Lung Cancer Drug Discovery and ...
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60
Histone deacetylase inhibitor - Wikipedia
https://en.wikipedia.org/wiki/Histone_deacetylase_inhibitor
Histone deacetylase inhibitors (HDAC inhibitors, HDACi, HDIs) are chemical compounds that inhibit histone deacetylases. HDIs have a long history of use in ...
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https://en.wikipedia.org/wiki/Histone_deacetylase_inhibitor
Histone deacetylase inhibitors (HDAC inhibitors, HDACi, HDIs) are chemical compounds that inhibit histone deacetylases. HDIs have a long history of use in ...
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61
EMT Inhibitor May Improve Oral Cancer Treatment
https://www.dentistrytoday.com/emt-inhibitor-may-improve-oral-cancer-treatment/
› emt-inhibitor-may-im...
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https://www.dentistrytoday.com/emt-inhibitor-may-improve-oral-cancer-treatment/
› emt-inhibitor-may-im...
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62
HDAC | Inhibitors - MedChemExpress
https://www.medchemexpress.com/Targets/HDAC.html
Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s ...
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https://www.medchemexpress.com/Targets/HDAC.html
Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s ...
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63
A novel form of cancer therapy: Targeting metastatic EMT (video)
https://www.khanacademy.org/college-careers-more/bjc/2015-challenge/2015-life-science/v/bjc-targeting-metastatic-emt
› bjc › 2015-life-science
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https://www.khanacademy.org/college-careers-more/bjc/2015-challenge/2015-life-science/v/bjc-targeting-metastatic-emt
› bjc › 2015-life-science
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64
Histone deacetylatse (HDAC) inhibitors - YouTube
https://www.youtube.com/watch?v=OBcpk-M5RYE
Apr 4, 2017
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https://www.youtube.com/watch?v=OBcpk-M5RYE
Apr 4, 2017
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65
EMT Resistance in Cancer Cells and Two Potential Causes
https://www.oncotarget.org/2021/10/21/emt-resistance-in-cancer-cells-and-two-potential-causes/
Epithelial–mesenchymal transition (EMT): losing cell polarity and cell adhesion to gain migratory and invasive properties. Listen to an audio ...
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https://www.oncotarget.org/2021/10/21/emt-resistance-in-cancer-cells-and-two-potential-causes/
Epithelial–mesenchymal transition (EMT): losing cell polarity and cell adhesion to gain migratory and invasive properties. Listen to an audio ...
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66
Renal Fibrosis: Mechanisms and Therapies
https://books.google.com/books?id=KXioDwAAQBAJ&pg=PA351&lpg=PA351&dq=emt+hdac+inhibitor&source=bl&ots=53SRdgemfH&sig=ACfU3U0a1s2GrDiHPhyLIiZIROl61y8Olg&hl=en&sa=X&ved=2ahUKEwj9laPCyMf7AhU6rokEHdTvD_EQ6AF6BQjzARAD
Inhibition of DNMT1 prevents TGF-β1-induced hypermethylation of the Smad7 gene promoter, ... The TGF-β1induced EMT is countered by silencing HDAC-2 in TECs.
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https://books.google.com/books?id=KXioDwAAQBAJ&pg=PA351&lpg=PA351&dq=emt+hdac+inhibitor&source=bl&ots=53SRdgemfH&sig=ACfU3U0a1s2GrDiHPhyLIiZIROl61y8Olg&hl=en&sa=X&ved=2ahUKEwj9laPCyMf7AhU6rokEHdTvD_EQ6AF6BQjzARAD
Inhibition of DNMT1 prevents TGF-β1-induced hypermethylation of the Smad7 gene promoter, ... The TGF-β1induced EMT is countered by silencing HDAC-2 in TECs.
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67
Lung Cancer Metastasis: Novel Biological Mechanisms and ...
https://books.google.com/books?id=2Sw1EHMTChwC&pg=PA121&lpg=PA121&dq=emt+hdac+inhibitor&source=bl&ots=gveZJ5Dd5Z&sig=ACfU3U1OE41KDWVQHIMKTZCifYgpOgZD2g&hl=en&sa=X&ved=2ahUKEwj9laPCyMf7AhU6rokEHdTvD_EQ6AF6BQjwARAD
combined HDAC inhibitor and gefitinib treatment may represent a potential ... Zeisberg et al. have reported that BMP-7 reverses the TGF-β1-induced EMT by ...
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https://books.google.com/books?id=2Sw1EHMTChwC&pg=PA121&lpg=PA121&dq=emt+hdac+inhibitor&source=bl&ots=gveZJ5Dd5Z&sig=ACfU3U1OE41KDWVQHIMKTZCifYgpOgZD2g&hl=en&sa=X&ved=2ahUKEwj9laPCyMf7AhU6rokEHdTvD_EQ6AF6BQjwARAD
combined HDAC inhibitor and gefitinib treatment may represent a potential ... Zeisberg et al. have reported that BMP-7 reverses the TGF-β1-induced EMT by ...
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68
Stem Cells and Cancer Stem Cells, Volume 11: Therapeutic ...
https://books.google.com/books?id=-YrHBAAAQBAJ&pg=PA271&lpg=PA271&dq=emt+hdac+inhibitor&source=bl&ots=-WQxqpC7pK&sig=ACfU3U27TTg_vlHpv35YZtnZDm4uaDlkpw&hl=en&sa=X&ved=2ahUKEwj9laPCyMf7AhU6rokEHdTvD_EQ6AF6BQjtARAD
See Histone deacetylase (HDAC) inhibitor Head and neck squamous cell carcinoma (HNSCC) in cisplatin, 20 and CSCs, 69–70 and EMT (see Epithelial-mesenchymal ...
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https://books.google.com/books?id=-YrHBAAAQBAJ&pg=PA271&lpg=PA271&dq=emt+hdac+inhibitor&source=bl&ots=-WQxqpC7pK&sig=ACfU3U27TTg_vlHpv35YZtnZDm4uaDlkpw&hl=en&sa=X&ved=2ahUKEwj9laPCyMf7AhU6rokEHdTvD_EQ6AF6BQjtARAD
See Histone deacetylase (HDAC) inhibitor Head and neck squamous cell carcinoma (HNSCC) in cisplatin, 20 and CSCs, 69–70 and EMT (see Epithelial-mesenchymal ...
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69
Multi-targeted Natural Products as Cancer Therapeutics: ...
https://books.google.com/books?id=3rhREAAAQBAJ&pg=PA23-IA157&lpg=PA23-IA157&dq=emt+hdac+inhibitor&source=bl&ots=NI6vFpCiks&sig=ACfU3U34eI6LX465kvCfDxZQw-QsWIdlOw&hl=en&sa=X&ved=2ahUKEwj9laPCyMf7AhU6rokEHdTvD_EQ6AF6BQjuARAD
Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib ... FOXM1 and EMT inhibition via hydroxygenkwanin-induced miR-320a expression.
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https://books.google.com/books?id=3rhREAAAQBAJ&pg=PA23-IA157&lpg=PA23-IA157&dq=emt+hdac+inhibitor&source=bl&ots=NI6vFpCiks&sig=ACfU3U34eI6LX465kvCfDxZQw-QsWIdlOw&hl=en&sa=X&ved=2ahUKEwj9laPCyMf7AhU6rokEHdTvD_EQ6AF6BQjuARAD
Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib ... FOXM1 and EMT inhibition via hydroxygenkwanin-induced miR-320a expression.
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