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1 Ribonucleic Acid (RNA)
https://www.genome.gov/genetics-glossary/RNA-Ribonucleic-Acid
Ribonucleic acid (abbreviated RNA) is a nucleic acid present in all living cells that has structural similarities to DNA.
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2 DNA & RNA - Site Guide - NCBI
https://www.ncbi.nlm.nih.gov/guide/dna-rna/
A collection of curated, non-redundant genomic DNA, transcript (RNA), and protein sequences produced by NCBI. RefSeqs provide a stable reference for genome ...
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3 What is RNA? - UMass Medical School
https://www.umassmed.edu/rti/biology/what-is-rna/
› rti › biology › what-is-rna
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4 What is RNA? - YourGenome
https://www.yourgenome.org/facts/what-is-rna/
Ribonucleic acid, or RNA, plays a key role in turning the instructions held in the DNA of your genome into functional proteins in your cells.
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5 Translation: DNA to mRNA to Protein | Learn Science at Scitable
https://www.nature.com/scitable/topicpage/translation-dna-to-mrna-to-protein-393/
Genes encode proteins, and the instructions for making proteins are decoded in two steps: first, a messenger RNA (mRNA) molecule is produced through the ...
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6 RNAcentral: The non-coding RNA sequence database
https://rnacentral.org/
RNAcentral is a comprehensive database of non-coding RNA sequences that represents all types of ncRNA from a broad range of organisms. RNAcentral is the ...
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7 RNA - Wikipedia
https://en.wikipedia.org/wiki/RNA
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes.
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8 3 Finding Genes with RNA-seq - Bookdown
https://bookdown.org/maria_gallegos/where-are-genes/chapter3.html
Regions of the genome that are transcriptionally active pinpoint the position of genes. The most important take home message for this chapter: RNA sequence ...
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9 Types of RNA: mRNA, rRNA and tRNA - News Medical
https://www.news-medical.net/life-sciences/-Types-of-RNA-mRNA-rRNA-and-tRNA.aspx
Ribosomal RNA (rRNA). rRNAs are found in the ribosomes and account for 80% of the total RNA present in the cell. Ribosomes are composed of a large subunit ...
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10 A survey of best practices for RNA-seq data analysis
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-0881-8
Ribonucleic acid (RNA) can fold back onto itself to form a base-paired secondary structure. This phenomenon confers functional specificity to a ...
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11 Editorial: RNA-Seq Analysis: Methods, Applications ... - Frontiers
https://www.frontiersin.org/articles/10.3389/fgene.2020.00220/full
RNA molecules are not linear, but fold into complex three-dimensional structures. Base pairing of proximal nucleotides generates secondary ...
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12 RNA | Definition, Structure, Types, & Functions - Britannica
https://www.britannica.com/science/RNA
RNA, abbreviation of ribonucleic acid, complex compound of high molecular weight that functions in cellular protein synthesis and replaces ...
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13 RNA-Seq - GDC Docs - National Cancer Institute
https://docs.gdc.cancer.gov/Encyclopedia/pages/RNA-Seq/
RNA-Seq data originates from extracted RNA that was reverse transcribed into DNA and sequenced on a next-generation sequencing platform. The number of reads ...
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14 RNA is an intermediary between DNA and protein
http://www.dnaftb.org/21/
DNA is found mostly in the cell nucleus, but another type of nucleic acid, RNA, is common in the cytoplasm. Watson and Crick proposed that RNA must copy the ...
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15 RNA-Seq FAQ
https://web.genewiz.com/rna-seq-faq
Since ribosomal RNA (rRNA) makes up the majority of total RNA, its removal is necessary for efficient sequencing of other RNA species, such as mRNA, long non- ...
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16 DNA transcription and mRNA processing (video)
https://www.khanacademy.org/science/ap-biology/gene-expression-and-regulation/transcription-and-rna-processing/v/transcription-and-mrna-processing
› science › ap-biology › tr...
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17 What is RNA | Genetics | Biology | FuseSchool - YouTube
https://www.youtube.com/watch?v=Y4p6jhFaru4
FuseSchool - Global Education
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18 RNA-Seq: Basics, Applications and Protocol
https://www.technologynetworks.com/genomics/articles/rna-seq-basics-applications-and-protocol-299461
RNA-seq lets us investigate and discover the transcriptome, the total cellular content of RNAs including mRNA, rRNA and tRNA. Understanding the ...
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19 RNA Sequence - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/medicine-and-dentistry/rna-sequence
First, RNA-seq does not need the sequences of genes to be detected. This means that RNA-seq can be used to identify transcripts in species without genomic ...
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20 What is RNA? | Live Science
https://www.livescience.com/what-is-RNA.html
More than just DNA's lesser-known cousin, RNA plays a central role in turning genetic information into your body's proteins. This remarkable ...
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21 RNAloops: a database of RNA multiloops - Oxford Academic
https://academic.oup.com/bioinformatics/article/38/17/4200/6637509
RNA molecules play a significant role in the functioning of living organisms and viruses. They carry out a broad range of functions—from translating genetic ...
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22 Bulk RNA-seq Data Standards and Processing Pipeline
https://www.encodeproject.org/data-standards/rna-seq/long-rnas/
Libraries must be generated from mRNA (poly(A)+, rRNA-depleted total RNA, or poly(A)- populations that are size-selected to be longer than approximately 200 bp.
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23 How do genes direct the production of proteins? - MedlinePlus
https://medlineplus.gov/genetics/understanding/howgeneswork/makingprotein/
The type of RNA that contains the information for making a protein is called messenger RNA (mRNA) because it carries the information, or message ...
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24 RNA | CK-12 Foundation
https://flexbooks.ck12.org/cbook/ck-12-middle-school-life-science-2.0/section/3.6/primary/lesson/rna-ms-ls/
Three RNAs · Messenger RNA (mRNA) carries the instructions from the nucleus to the cytoplasm. mRNA is produced in the nucleus, as are all RNAs.
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25 DNA and RNA Sequencing - Lustgarten Foundation
https://lustgarten.org/leadership/your-impact/projects/personalized-medicine/dna-rna-sequencing/
Much like DNA, RNA (ribonucleic acid) is an essential component in many biological roles. Different types of RNA exist in the cell to perform various roles, ...
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26 What are two places in the cell where RNA is found?
https://homework.study.com/explanation/what-are-two-places-in-the-cell-where-rna-is-found.html
The two places that RNA is found in the cell is the nucleus and the cytoplasm. RNA is synthesized from DNA during the process of transcription, which happens ...
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27 RNA-seq: from technology to biology | SpringerLink
https://link.springer.com/article/10.1007/s00018-009-0180-6
Ribosomes are riboprotein complexes mediating the translation of RNA transcripts into proteins and are probably the most abundant RNA-binding ...
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28 RNA-Seq Data Analysis | RNA sequencing software tools
https://www.illumina.com/informatics/sequencing-data-analysis/rna.html
Find out how to analyze RNA-Seq data with user-friendly software tools packaged in intuitive user interfaces designed for biologists.
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29 Reference-based RNA-Seq data analysis - Galaxy Training!
https://training.galaxyproject.org/training-material/topics/transcriptomics/tutorials/ref-based/tutorial.html
One of the most common aims of RNA-Seq is the profiling of gene expression by identifying genes or molecular pathways that are differentially expressed (DE) ...
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30 ARCHS4
https://maayanlab.cloud/archs4/
ARCHS4: Massive Mining of Publicly Available RNA-seq Data from Human and Mouse. Get Started. All RNA-seq and ChIP-seq sample and signature search (ARCHS4) ...
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31 OneStopRNAseq: A Web Application for Comprehensive and ...
https://www.mdpi.com/2073-4425/11/10/1165
OneStopRNAseq has user-friendly interfaces and offers workflows for common types of RNA-seq data analyses, such as comprehensive data-quality control, ...
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32 Lesson 9: RNA Seq Data | STAT 555
https://online.stat.psu.edu/stat555/node/13/
Sequencing starts with an RNA sample from a tissue. This may be preprocessed to enrich for certain types of RNA, such as RNA with poly-A tails. Usually it is ...
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33 What is RNA? | New Scientist
https://www.newscientist.com/definition/rna/
RNA (ribose nucleic acid) is a complex molecule that plays a big part in living cells. It is similar in structure … to DNA, which carries the genes that give ...
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34 A Quick Start Guide to RNA-Seq Data Analysis
https://www.azenta.com/blog/quick-start-guide-rna-seq-data-analysis
What You Need for RNA-Seq Analysis · Hardware. Linux environment or server. Accessed via shell terminals, such as PuTTY or MobaXterm; Can use a ...
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35 RNAfold web server - Vienna RNA
http://rna.tbi.univie.ac.at/cgi-bin/RNAWebSuite/RNAfold.cgi
The RNAfold web server will predict secondary structures of single stranded RNA or DNA sequences. Current limits are 7,500 nt for partition function ...
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36 RNA, no mere messenger, calls some shots in gene activity ...
https://news.stanford.edu/news/2007/july11/med-rna-071107.html
Researchers have discovered a new type of RNA molecule that can indicate where a cell is located in the human body.
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37 How To Find Rna-Seq Data Of Published Papers? - Biostars
https://www.biostars.org/p/78269/
The following three papers have large RNA-seq data sets in open-access ... Whole transcriptome RNA-Seq analysis of breast cancer recurrence risk using ...
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38 rMATS: Robust and flexible detection of differential alternative ...
https://www.pnas.org/doi/10.1073/pnas.1419161111
Of note, pooling RNAs or merging RNA-Seq data from multiple replicates is not an effective approach to account for variability, and the result is particularly ...
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39 DNA and RNA - Computational Medicine Center
https://cm.jefferson.edu/learn/dna-and-rna/
DNA, along with RNA and proteins, is one of the three major macromolecules that are essential for life. Most of the DNA is located in the nucleus, although a ...
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40 Analysis workflow of publicly available RNA-sequencing ...
https://star-protocols.cell.com/protocols/931
RNA-seq data organization and count normalization. Timing: 1 h. Before performing differential gene expression analysis, it is required to ...
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41 Bringing RNA into genomics | MIT News
https://news.mit.edu/2020/bringing-rna-genomics-0729
By studying RNA-binding proteins, a research consortium known as ENCODE (Encyclopedia of DNA Elements) has identified genomic sites that ...
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42 Why Look at RNA Instead of DNA? | Discovering the Genome
https://discoveringthegenome.org/discovering-genome/rna-sequencing/why-look-rna-instead-dna
If the RNA in our bodies is essentially copied from our DNA, why might we want to study RNA instead?Consider this: A neuron in your brain and a macrophage ...
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43 RNA-seqlopedia
https://rnaseq.uoregon.edu/
Convert the RNA to cDNA; add sequencing adapters. Sequence. Sequence cDNAs using a sequencing platform. Analysis.
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44 RNA-Seq Blog
https://www.rna-seqblog.com/
The technology of single cell RNA sequencing (scRNA-seq) has gained massively in popularity as it allows unprecedented insights into cellular heterogeneity ...
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45 The 3 Types of RNA and Their Functions - ThoughtCo
https://www.thoughtco.com/types-of-rna-and-their-functions-606386
rRNA is located in the cytoplasm of a cell, where ribosomes are found. rRNA directs the translation of mRNA into proteins. tRNA or Transfer RNA.
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46 Current best practices in single‐cell RNA‐seq analysis: a tutorial
https://www.embopress.org/doi/10.15252/msb.20188746
Single-cell RNA-seq has enabled gene expression to be studied at an unprecedented resolution. The promise of this technology is attracting a ...
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47 Twenty years of RNA: reflections from the RNP world
https://rnajournal.cshlp.org/content/21/4/690.long
The very next year, Tim Nilsen and the RNA Society launched the journal that you now ... In the first of those two decades (1975–1985), non-coding RNAs held ...
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48 transcription - from DNA to RNA - Chemguide
https://www.chemguide.co.uk/organicprops/aminoacids/dna3.html
The code is first transcribed ("copied", although with one important difference - see later) to messenger RNA. That then travels out of the nucleus of the cell ...
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49 Rfam: The RNA families database
https://rfam.xfam.org/
The Rfam database is a collection of RNA families, each represented by multiple sequence alignments, consensus secondary structures and covariance models.
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50 Ribonucleic acid (RNA) - Genomics Education Programme
https://www.genomicseducation.hee.nhs.uk/glossary/ribonucleic-acid-rna/
RNA is crucial for protein production. As DNA cannot leave the nucleus the relevant sections are transcribed into messenger RNA (mRNA) and ...
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51 Very Few RNA and DNA Sequence Differences in the Human ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0025842
RNA editing is an important cellular process by which the nucleotides in a mature RNA transcript are altered to cause them to differ from ...
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52 RNA Sequencing Services | Psomagen
https://www.psomagen.com/rna-sequncing
See how RNA sequencing can provide transcriptome sequence and abundance data for types of ribonucleic acid such as mRNA, miRNA, smRNA & lncRNA.
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53 Fact Sheet: Genome, DNA, RNA | CD Genomics Blog
https://www.cd-genomics.com/blog/fact-sheet-genome-dna-rna/
Another type of nucleic acid is RNA, or ribonucleic acid. RNA translates DNA into proteins, and is the genetic material of some prokaryotes and ...
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54 RNA‐seq: Applications and Best Practices - IntechOpen
https://www.intechopen.com/chapters/55603
RNA‐sequencing (RNA‐seq) is the state‐of‐the‐art technique for transcriptome analysis that takes advantage of high‐throughput next‐generation sequencing.
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55 RNA | Biomacromolecular structures - EMBL-EBI
https://www.ebi.ac.uk/training/online/courses/biomacromolecular-structures/rna/
Some viruses use RNA instead of DNA as their genetic material. Most of the RNA, however, does not code for proteins. These RNAs are called noncoding (ncRNA) and ...
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56 ENC RNA-seq Tracks - UCSC Genome Browser
https://genome.ucsc.edu/cgi-bin/hgTrackUi?db=hg19&g=wgEncodeRnaSeqSuper
RNA-seq is performed by reverse-transcribing an RNA sample into cDNA followed by high throughput DNA sequencing. Most data is produced in the format of either ...
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57 Nucleic Acids - RNA - Beckman Coulter
https://www.beckman.com/resources/sample-type/bio-molecules/nucleic-acids---rna
Messenger RNA (mRNA) is synthesized from DNA in the nucleus and enters the surrounding cytoplasm where it can interact with cellular ribosomes to begin the ...
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58 Identifying Differentially Expressed Genes from RNA-Seq Data
https://www.mathworks.com/help/bioinfo/ug/identifying-differentially-expressed-genes-from-rna-seq-data.html
A typical differential expression analysis of RNA-Seq data consists of normalizing the raw counts and performing statistical tests to reject or accept the ...
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59 Cell Types Database: RNA-Seq Data - brain-map.org
https://portal.brain-map.org/atlases-and-data/rnaseq
Single cell (or single nucleus) RNA sequencing (RNA-Seq) is a scalable approach to provide genome-wide expression profiles for thousands of cells.
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60 RNA-seq datasets – The Green Lab - Faculty Websites - UCI
https://faculty.sites.uci.edu/kimgreen/rna-seq-datasets/
Please select from the links below to explore our RNA-seq datasets in an interactive fashion. Datasets related to microglia depletion or CSF1R inhibitor ...
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61 RSEQREP: RNA-Seq Reports, an open-source...
https://f1000research.com/articles/6-2162
RNA-Seq is increasingly being used to measure human RNA expression on a genome-wide scale. Expression profiles can be interrogated to identify and ...
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62 The Rise of RNA: The Cellular Workhorse Behind a New ...
https://www.pfizer.com/news/articles/the_rise_of_rna_the_cellular_workhorse_behind_a_new_class_of_next_gen_therapies
Transfer RNA, or tRNA, located in the cytoplasm of the cell, ferries amino acids to form protein polypeptide chains in the ribosome. The structure of tRNA is ...
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63 Full article: Identification of RNA 3´ ends and termination sites ...
https://www.tandfonline.com/doi/full/10.1080/15476286.2020.1723328
Archaeal RNA synthesis is generally considered to be more closely related to transcription in eukaryotes than to bacterial transcription.
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64 Beyond DNA for Unparalleled Clarity: RNA Genetic Testing
https://www.ambrygen.com/providers/genetic-testing/rna
+RNAinsight provides comprehensive gene coverage for RNA analysis to help classify DNA variants associated with cancers of breast, ovarian, prostate, colon, ...
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65 Methods of RNA Quality Assessment - Promega Corporation
https://www.promega.com/resources/pubhub/methods-of-rna-quality-assessment/
RNA is extremely susceptible to degradation due to the ubiquitous presence of RNases in the environment. Successful RNA analysis involves not only careful ...
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66 Analysis of Transcriptome Complexity Through RNA ...
https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.111.249433
In addition to overall gene expression analysis, the methods developed in this study were used to analyze RNA-Seq data with respect to ...
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67 DNA -> RNA & Codons - UMass Amherst
https://www.umass.edu/microbio/chime/dna/codons.htm
As shown schematically above, messenger RNA is synthesized complementary and antiparallel to the template strand (anticodons) of DNA, so the resulting mRNA ...
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68 RNA Sequencing (Including Single-Cell RNA-Seq)
https://www.cgm.northwestern.edu/cores/nuseq/services/next-generation-sequencing/rna-seq.html
RNA sequencing, or RNA-seq, is the latest technology to study the transcriptome, i.e., the full set of RNA transcripts as genome readouts in a cell or ...
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69 Unlocking the Value of RNA Data - Tempus
https://www.tempus.com/news/unlocking-the-value-of-rna-data/
Whole transcriptome RNA sequencing measures gene expression comprehensively across adult human coding genes, which is the portion of a gene's ...
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70 DNA<->RNA->protein - Biomodel
https://biomodel.uah.es/en/lab/cybertory/analysis/trans.htm
Transcription and Translation Tool. Converts sequences from DNA to RNA and from this to protein. DNA (deoxyribonucleic acid. permanent copy of the genetic ...
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71 Methods for Detecting Protein–RNA Interactions - US
https://www.thermofisher.com/us/en/home/life-science/protein-biology/protein-biology-learning-center/protein-biology-resource-library/pierce-protein-methods/methods-detecting-protein-rna-interactions.html
Traditionally, RNA probes are radioactively labeled for detection, although fluorescent and chemiluminescent detection is also possible. Non-radioactive RNA end ...
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72 COVID-19 vaccine: What's RNA research got to do with it?
https://www.rochester.edu/newscenter/covid-19-rna-coronavirus-research-428952/
RNA research at the University of Rochester provides a foundation for developing antiviral drugs, vaccines, and other therapeutics to ...
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73 RNA LEXICON Chapter #12 – Data Analysis and Quality Control
https://www.lexogen.com/rna-lexicon-data-analysis-and-quality-control-secondary-analysis/
Learn about secondary analysis of RNA-Seq data: alignment of sequencing reads, UMI-based read collapsing, and quantification of reads.
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74 RNA-seq Analysis & Biomarker Discovery Portal - GeneGlobe
https://geneglobe.qiagen.com/us/analyze/rnaseq-analysis-and-biomarker-discovery-portal
Want to take the stress out of data analysis and fast-track your path to gene expression insights? With our new RNA-seq Analysis Portal, go from FASTQ files ...
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75 Discovery of messenger RNA in 1961 - Institut Pasteur
https://www.pasteur.fr/en/home/research-journal/news/discovery-messenger-rna-1961
What exactly is this messenger RNA? Who discovered it, and when? Our story starts sixty years ago, at the Institut Pasteur in Paris. For the past ten years, ...
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76 Atlas of Subcellular RNA Localization Revealed by APEX-seq
https://www.biorxiv.org/content/10.1101/454470v2.full.pdf
as RNA localization and underlying genome architecture. An analysis of mRNAs at the outer mitochondrial membrane suggests distinct ...
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77 Center for RNA Biology and Therapeutics - City of Hope
https://www.cityofhope.org/research/beckman-research-institute/center-for-rna-biology-and-therapeutics
This multistep process, which is fundamental to human biology, also involves transfer RNA (tRNA), which decodes mRNA, and ribosomal RNA (rRNA), which forms the ...
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78 RNA-Seq Alignment & Analysis - DNASTAR
https://www.dnastar.com/workflows/rna-seq/
Align RNA-Seq data sets, perform statistical analysis and visualize relationships between genes using Lasergene Genomics. Click to find out more!
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79 RNA Sequence Analysis - Bioinformatics Workbook
https://bioinformaticsworkbook.org/dataAnalysis/RNA-Seq/RNA-SeqIntro/RNAseq-using-a-genome.html
RNA-seq was carried out in Illumina Hiseq 2500. The sequencing reads were generated as paired-end data, hence we have 2 files per replicate. Condition ...
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80 RNA: What it is, what it does, and why it's one of life's most ...
https://www.sciencefocus.com/the-human-body/rna/
The RNA world is a theory related to the origin of life. More precisely, it's a hypothesis for how genes replicated and adapted on prebiotic ...
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81 Gene Expression: RNA-seq - Bioinformatics Core
https://med.virginia.edu/bioinformatics-core/services/gene-expression-rna-seq/
Microarrays offer a limited ability to fully catalog and quantify the diverse spectrum of RNA molecules expressed from cellular genomes, and are of little ...
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82 Rna Definition & Meaning - Dictionary.com
https://www.dictionary.com/browse/rna
› browse › rna
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83 RNA sequencing and gene expression analysis
https://nanoporetech.com/applications/rna-sequencing
Long-read nanopore RNA sequencing - accurate quantification and complete, full-length characterisation of native RNA or cDNA without fragmentation or ...
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84 csRNA-seq - Homer Software and Data Download
http://homer.ucsd.edu/homer/ngs/csRNAseq/index.html
Most researchers are interested in RNA polymerase II transcripts (i.e. mRNA, eRNA, etc.), and as a result, most methods focus on the identification of RNAs ...
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85 RNA Synthesis and Processing
http://www2.csudh.edu/nsturm/CHEMXL153/RNASynthesisProcessing.htm
Most eukaryotic RNA must be transported across the nuclear membrane where it is processed then transported to the cytosol. Processing helps stabilize and ...
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86 Finding the target sites of RNA‐binding proteins - Li
https://onlinelibrary.wiley.com/doi/10.1002/wrna.1201
Abstract RNA–protein interactions differ from DNA–protein interactions because of the central role of RNA secondary structure.
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87 Complete Guide to Understanding Single-Cell RNA-Seq
https://www.activemotif.com/blog-single-cell-rna-seq
The RNA-Seq protocol first starts with total RNA isolation. DNA and solvent contaminations have to be avoided. After RNA isolation, ribosomal ...
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88 Advances in RNA-Seq - Bio-Rad
https://www.bio-rad.com/en-us/applications-technologies/advances-rna-seq?ID=Q106Z9SCUMB7
A detailed analysis of the transcriptome, which is the total collection of transcribed RNA in an organism – mRNA, rRNA, tRNA, and noncoding RNA – is ...
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89 The DNA, RNA and Proteins - Bioinformatics.org
https://www.bioinformatics.org/tutorial/1-1.html
Mutations are changes in gene's DNA sequence. RNA is somewhat similar to DNA; they both are nucleic acids of nitrogen-containing bases joined by sugar-phosphate ...
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90 RNA Seq - Canopy Biosciences
https://canopybiosciences.com/rna-seq/
Sequencing RNA provides both abundance and sequence information yielding a deep understanding of gene expression. RNA Seq services from Canopy Biosciences ...
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91 RNA-seq Tutorial (with Reference Genome)
https://bioinformatics.uconn.edu/resources-and-events/tutorials-2/rna-seq-tutorial-with-reference-genome/
This tutorial will serve as a guideline for how to go about analyzing RNA sequencing data when a reference genome is available.
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92 The search for RNA-binding proteins: a technical and ...
https://portlandpress.com/biochemsoctrans/article/49/1/393/227660/The-search-for-RNA-binding-proteins-a-technical
The RBP–RNA complexes derived from RNA-centric and phase separation methods can be prepared for either RNA Seq or MS proteomics. (v) Sequencing ...
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