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Google Keyword Rankings for : colon wnt
1
Wnt signaling in colorectal cancer: pathogenic role and ...
https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-022-01616-7
The canonical Wnt signaling pathway regulates cell pluripotency and determines the differentiation fate of cells during development. The ...
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https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-022-01616-7
The canonical Wnt signaling pathway regulates cell pluripotency and determines the differentiation fate of cells during development. The ...
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2
Emerging Roles of Wnt Ligands in Human Colorectal Cancer
https://www.frontiersin.org/articles/10.3389/fonc.2020.01341/full
Wnt ligands (Wnts) are secreted glycoproteins and fundamentally essential for the transduction of Wnt signaling pathway. However, the 19 members ...
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https://www.frontiersin.org/articles/10.3389/fonc.2020.01341/full
Wnt ligands (Wnts) are secreted glycoproteins and fundamentally essential for the transduction of Wnt signaling pathway. However, the 19 members ...
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3
Targeting Wnt signaling in colorectal cancer. A Review in the ...
https://journals.physiology.org/doi/full/10.1152/ajpcell.00117.2015
Wnt signaling is activated at the bottom of the intestinal crypts, which is crucial for stem cell maintenance and tissue homeostasis. Aberrant Wnt activation is ...
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https://journals.physiology.org/doi/full/10.1152/ajpcell.00117.2015
Wnt signaling is activated at the bottom of the intestinal crypts, which is crucial for stem cell maintenance and tissue homeostasis. Aberrant Wnt activation is ...
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4
Epithelial Wnt secretion drives the progression of ... - Cell Press
https://www.cell.com/iscience/pdf/S2589-0042(21)01340-7.pdf
Various studies in colorectal cancer (CRC) have demonstrated that mutations in the Wnt/b-catenin signaling pathway are the key driving force for ...
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https://www.cell.com/iscience/pdf/S2589-0042(21)01340-7.pdf
Various studies in colorectal cancer (CRC) have demonstrated that mutations in the Wnt/b-catenin signaling pathway are the key driving force for ...
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5
Wnt signaling in cancer | Oncogene - Nature
https://www.nature.com/articles/onc2016304
The impact of Wnt signaling on carcinogenesis of colorectal cancer is well-studied (reviewed in Polakis). Loss of APC is the main driver of Wnt ...
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https://www.nature.com/articles/onc2016304
The impact of Wnt signaling on carcinogenesis of colorectal cancer is well-studied (reviewed in Polakis). Loss of APC is the main driver of Wnt ...
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6
Disruption of β-Catenin–Dependent Wnt Signaling in Colon ...
https://aacrjournals.org/mcr/article/20/3/468/681668/Disruption-of-Catenin-Dependent-Wnt-Signaling-in
Mutations that activate the Wnt signaling pathway have long been characterized as a hallmark of colon cancer, and multiple studies have pointed ...
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https://aacrjournals.org/mcr/article/20/3/468/681668/Disruption-of-Catenin-Dependent-Wnt-Signaling-in
Mutations that activate the Wnt signaling pathway have long been characterized as a hallmark of colon cancer, and multiple studies have pointed ...
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7
Human colon organoids reveal distinct physiologic and ...
https://rupress.org/jem/article/216/3/704/120372/Human-colon-organoids-reveal-distinct-physiologic
Targeting Wnt signaling has proven difficult because the pathway is crucial for homeostasis and stem cell renewal. To distinguish oncogenic from ...
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https://rupress.org/jem/article/216/3/704/120372/Human-colon-organoids-reveal-distinct-physiologic
Targeting Wnt signaling has proven difficult because the pathway is crucial for homeostasis and stem cell renewal. To distinguish oncogenic from ...
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8
The canonical Wnt signalling pathway and its APC ... - Gut
https://gut.bmj.com/content/56/3/417
Thus, the epithelium of the colon is under perpetual renewal. Wnt growth factors activate a cascade of intracellular events, which is known as the canonical ...
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https://gut.bmj.com/content/56/3/417
Thus, the epithelium of the colon is under perpetual renewal. Wnt growth factors activate a cascade of intracellular events, which is known as the canonical ...
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9
Wnt signaling in the intestinal epithelium: from endoderm to ...
http://genesdev.cshlp.org/content/19/8/877.full
Wnt signaling in the adult intestine promotes proliferation of progenitor or transit-amplifying (TA) cells, as well as commitment toward secretory lineages. Wnt ...
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http://genesdev.cshlp.org/content/19/8/877.full
Wnt signaling in the adult intestine promotes proliferation of progenitor or transit-amplifying (TA) cells, as well as commitment toward secretory lineages. Wnt ...
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10
Regulation of Wnt receptor activity: Implications for therapeutic ...
https://www.jbc.org/article/S0021-9258(21)00575-5/fulltext
... Implications for therapeutic development in colon cancer ... of Wnt/β-catenin (canonical) signaling in colorectal cancers (CRCs) was ...
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https://www.jbc.org/article/S0021-9258(21)00575-5/fulltext
... Implications for therapeutic development in colon cancer ... of Wnt/β-catenin (canonical) signaling in colorectal cancers (CRCs) was ...
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11
Not All Wnt Activation Is Equal: Ligand-Dependent versus ...
https://www.mdpi.com/2072-6694/12/11/3355
Wnt signaling is ubiquitously activated in colorectal tumors and driver mutations are identified in genes such as APC, CTNNB1, RNF43 and R-spondin (RSPO2/3) ...
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https://www.mdpi.com/2072-6694/12/11/3355
Wnt signaling is ubiquitously activated in colorectal tumors and driver mutations are identified in genes such as APC, CTNNB1, RNF43 and R-spondin (RSPO2/3) ...
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12
Aberrant Wnt/β-catenin signaling can induce chromosomal ...
https://www.pnas.org/doi/10.1073/pnas.0604206103
Adenovirus Dkk1 (Ad Dkk1) treatment of adult mice repressed expression of the Wnt target genes CD44 and EphB2 within 2 days in both small intestine and colon, ...
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https://www.pnas.org/doi/10.1073/pnas.0604206103
Adenovirus Dkk1 (Ad Dkk1) treatment of adult mice repressed expression of the Wnt target genes CD44 and EphB2 within 2 days in both small intestine and colon, ...
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13
Wnt/β-catenin signaling pathway is involved in induction of ...
https://tcr.amegroups.com/article/view/31664/html
Conclusions: Our present study demonstrated that the growth inhibition and apoptosis induction in colon cancer COLO205 cells by oridonin could be partially ...
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https://tcr.amegroups.com/article/view/31664/html
Conclusions: Our present study demonstrated that the growth inhibition and apoptosis induction in colon cancer COLO205 cells by oridonin could be partially ...
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14
Replication Study: Wnt activity defines colon cancer stem cells ...
https://elifesciences.org/articles/45426
Vermeulen et al. (2010) reported that colon cancer cell subpopulations with high Wnt activity correlated with markers of cancer stems cells (CSC) ...
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https://elifesciences.org/articles/45426
Vermeulen et al. (2010) reported that colon cancer cell subpopulations with high Wnt activity correlated with markers of cancer stems cells (CSC) ...
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15
Wnt/β-Catenin Is Essential for Intestinal Homeostasis and ...
https://journals.asm.org/doi/10.1128/MCB.01034-07
The Wnt signaling pathway is deregulated in over 90% of human colorectal cancers. β-Catenin, the central signal transducer of the Wnt ...
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https://journals.asm.org/doi/10.1128/MCB.01034-07
The Wnt signaling pathway is deregulated in over 90% of human colorectal cancers. β-Catenin, the central signal transducer of the Wnt ...
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16
A novel β-catenin/BCL9 complex inhibitor blocks oncogenic ...
https://www.science.org/doi/10.1126/sciadv.abm3108
Dysregulated Wnt/β-catenin signaling is implicated in the pathogenesis of many human cancers, including colorectal cancer (CRC), ...
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https://www.science.org/doi/10.1126/sciadv.abm3108
Dysregulated Wnt/β-catenin signaling is implicated in the pathogenesis of many human cancers, including colorectal cancer (CRC), ...
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17
Metabolic balance in colorectal cancer is maintained by ...
https://www.embopress.org/doi/10.15252/msb.202110874
Wnt pathways are important for the modulation of tissue homeostasis, and their deregulation is linked to cancer development.
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https://www.embopress.org/doi/10.15252/msb.202110874
Wnt pathways are important for the modulation of tissue homeostasis, and their deregulation is linked to cancer development.
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18
Wnt signaling in cancer stem cells and colon cancer metastasis
https://f1000research.com/articles/5-699
In the normal intestine and colon, Wnt signaling controls the homeostasis of intestinal stem cells (ISCs) that fuel, via proliferation, upward movement of ...
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https://f1000research.com/articles/5-699
In the normal intestine and colon, Wnt signaling controls the homeostasis of intestinal stem cells (ISCs) that fuel, via proliferation, upward movement of ...
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19
The inhibition of Wnt/β-catenin signalling by 1α,25 ...
https://erc.bioscientifica.com/view/journals/erc/14/1/0140141.xml
The Wnt/β-catenin signalling pathway is activated in 90% of human colon cancers by nuclear accumulation of β-catenin protein due to its own mutation or to ...
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https://erc.bioscientifica.com/view/journals/erc/14/1/0140141.xml
The Wnt/β-catenin signalling pathway is activated in 90% of human colon cancers by nuclear accumulation of β-catenin protein due to its own mutation or to ...
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20
MYC hyperactivates WNT signaling in APC/CTNNB1-mutated ...
http://biorxiv.org/cgi/reprint/2021.07.26.453875v1
and human colon cancer cells despite the presence of downstream activating mutations in the Wnt pathway. Conversely, MYC overexpression in ...
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http://biorxiv.org/cgi/reprint/2021.07.26.453875v1
and human colon cancer cells despite the presence of downstream activating mutations in the Wnt pathway. Conversely, MYC overexpression in ...
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21
Wnt and BMP signals control intestinal adenoma cell fates
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.27500
tumor cells to normal intestinal stem cells, which immediately reinstall the cellular ... signature of colon cancer-specific Wnt/b-catenin targets from.
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https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.27500
tumor cells to normal intestinal stem cells, which immediately reinstall the cellular ... signature of colon cancer-specific Wnt/b-catenin targets from.
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22
Wnt/β‑catenin signaling: Causes and treatment targets of drug ...
https://www.spandidos-publications.com/10.3892/mmr.2020.11744
Colorectal cancer (CRC) is the third most common malignant tumor in humans. Chemotherapy is used for the treatment of CRC.
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https://www.spandidos-publications.com/10.3892/mmr.2020.11744
Colorectal cancer (CRC) is the third most common malignant tumor in humans. Chemotherapy is used for the treatment of CRC.
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23
WNT and β-Catenin in Cancer: Genes and Therapy
https://www.annualreviews.org/doi/10.1146/annurev-cancerbio-030419-033628
2015). Figure 2 The abundance of potentially activating WNT pathway mutations in various cancers: (a) colorectal adenocarcinoma, (b) uterine corpus ...
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https://www.annualreviews.org/doi/10.1146/annurev-cancerbio-030419-033628
2015). Figure 2 The abundance of potentially activating WNT pathway mutations in various cancers: (a) colorectal adenocarcinoma, (b) uterine corpus ...
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24
Aberrant activation of the CD45-Wnt signaling axis promotes ...
https://www.thno.org/v11p8755.htm
Division of Colon and Rectal Surgery, Department of Surgery, ... Colorectal cancer, Therapy resistance, CD45, Cancer stem-like cell, Wnt, β-Catenin ...
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https://www.thno.org/v11p8755.htm
Division of Colon and Rectal Surgery, Department of Surgery, ... Colorectal cancer, Therapy resistance, CD45, Cancer stem-like cell, Wnt, β-Catenin ...
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25
Oncogenic K-ras Stimulates Wnt Signaling in Colon Cancer ...
https://www.gastrojournal.org/article/S0016-5085(05)00628-1/abstract
Background & Aims: Two key genetic events underlying the development of colon cancer are activation of the K-ras and Wnt signaling pathways.
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https://www.gastrojournal.org/article/S0016-5085(05)00628-1/abstract
Background & Aims: Two key genetic events underlying the development of colon cancer are activation of the K-ras and Wnt signaling pathways.
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26
Wnt Target genes | The Wnt Homepage
https://web.stanford.edu/group/nusselab/cgi-bin/wnt/target_genes
› group › nusselab › cgi-bin
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https://web.stanford.edu/group/nusselab/cgi-bin/wnt/target_genes
› group › nusselab › cgi-bin
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27
Colonic healing requires Wnt produced by epithelium as well ...
https://journals.biologists.com/dev/article/149/1/dev199587/273981/Colonic-healing-requires-Wnt-produced-by
Although Wnt signaling is clearly important for the intestinal epithelial homeostasis, the relevance of various sources of Wnt ligands ...
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https://journals.biologists.com/dev/article/149/1/dev199587/273981/Colonic-healing-requires-Wnt-produced-by
Although Wnt signaling is clearly important for the intestinal epithelial homeostasis, the relevance of various sources of Wnt ligands ...
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28
Wnt-expressing cells in the intestines: guides for tissue ...
https://academic.oup.com/jb/article/161/1/19/2682448
Involvement of the Wnt pathway in the Tip60/p400 control of colon cancer ... that Tip60 is a tumor suppressor in colon by repressing Wnt signaling.
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https://academic.oup.com/jb/article/161/1/19/2682448
Involvement of the Wnt pathway in the Tip60/p400 control of colon cancer ... that Tip60 is a tumor suppressor in colon by repressing Wnt signaling.
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29
Intestinal Wnt in the transition from physiology to oncology.
https://europepmc.org/article/pmc/8966512
Furthermore, the central role of the Wnt signaling pathway in intestinal carcinogenesis as well as its clinical relevance in colorectal ...
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https://europepmc.org/article/pmc/8966512
Furthermore, the central role of the Wnt signaling pathway in intestinal carcinogenesis as well as its clinical relevance in colorectal ...
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30
2265.full.pdf - The Journal of Immunology
https://www.jimmunol.org/content/205/8/2265.full.pdf?with-ds=yes
The Wnt–b-Catenin–IL-10 Signaling Axis in Intestinal APCs. Protects Mice from Colitis-Associated Colon Cancer in. Response to Gut Microbiota.
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https://www.jimmunol.org/content/205/8/2265.full.pdf?with-ds=yes
The Wnt–b-Catenin–IL-10 Signaling Axis in Intestinal APCs. Protects Mice from Colitis-Associated Colon Cancer in. Response to Gut Microbiota.
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31
Wnt signalling in stem cells and cancer
https://www.hubrecht.eu/app/uploads/2017/11/nature03319.pdf
Insights gained from understanding how the. Wnt pathway is integrally involved in both stem cell and cancer cell maintenance and growth in the intestinal, ...
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https://www.hubrecht.eu/app/uploads/2017/11/nature03319.pdf
Insights gained from understanding how the. Wnt pathway is integrally involved in both stem cell and cancer cell maintenance and growth in the intestinal, ...
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32
Butyrate and Wnt signaling
https://www.tandfonline.com/doi/pdf/10.4161/cc.7.9.5818
Fiber, Wnt signaling and colon cancer risk www.landesbioscience.com. Cell Cycle. 1179 of fish oil and pectin in suppressing intestinal ...
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https://www.tandfonline.com/doi/pdf/10.4161/cc.7.9.5818
Fiber, Wnt signaling and colon cancer risk www.landesbioscience.com. Cell Cycle. 1179 of fish oil and pectin in suppressing intestinal ...
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33
Wnt Proteins in Intestinal Epithelial Progenitor Cells
https://www.rndsystems.com/resources/posters/wnt-proteins-intestinal-epithelial-progenitor-cells
Wnt ligands, receptors, and inhibitors are differentially expressed along the intestinal crypt-villus axis and function as major stem cell niche factors ...
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https://www.rndsystems.com/resources/posters/wnt-proteins-intestinal-epithelial-progenitor-cells
Wnt ligands, receptors, and inhibitors are differentially expressed along the intestinal crypt-villus axis and function as major stem cell niche factors ...
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34
Significance of gene mutations in the Wnt signaling pathway ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0229262
Recent studies have shown that colorectal serrated lesions, which include sessile serrated adenomas (SSAs) and traditional serrated adenomas ...
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0229262
Recent studies have shown that colorectal serrated lesions, which include sessile serrated adenomas (SSAs) and traditional serrated adenomas ...
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35
JQ-1 Inhibits Colon Cancer Proliferation via Suppressing Wnt ...
https://pubs.acs.org/doi/10.1021/acs.chemrestox.7b00346
(14,15) We hypothesize that JQ-1 inhibits colon cancer progression partly through the regulation of Wnt signaling. Besides, high miR-21 has ...
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https://pubs.acs.org/doi/10.1021/acs.chemrestox.7b00346
(14,15) We hypothesize that JQ-1 inhibits colon cancer progression partly through the regulation of Wnt signaling. Besides, high miR-21 has ...
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36
Wnt Signaling and Drug Resistance in Cancer
https://molpharm.aspetjournals.org/content/97/2/72
In colorectal cancer, even though most of the cancer cases have elevated Wnt/β-catenin signaling due to mutations/alterations in the Wnt pathway ...
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https://molpharm.aspetjournals.org/content/97/2/72
In colorectal cancer, even though most of the cancer cases have elevated Wnt/β-catenin signaling due to mutations/alterations in the Wnt pathway ...
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37
Selective Wnt/β-catenin Small-molecule Inhibitor CWP232228 ...
https://ar.iiarjournals.org/content/39/7/3661
Cancers of the colonic region or colorectal cancer (CRC) remains a significant life-threating disease worldwide, and in Korea, is the second and third most ...
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https://ar.iiarjournals.org/content/39/7/3661
Cancers of the colonic region or colorectal cancer (CRC) remains a significant life-threating disease worldwide, and in Korea, is the second and third most ...
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38
Toward Colorectal Cancer Biomarkers: The Role of Genetic ...
https://www.liebertpub.com/doi/10.1089/omi.2020.0231
The Wnt pathway had the greatest portion of DEGs, including activators, inhibitors, and associated long noncoding RNAs (lncRNAs), suggesting the ...
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https://www.liebertpub.com/doi/10.1089/omi.2020.0231
The Wnt pathway had the greatest portion of DEGs, including activators, inhibitors, and associated long noncoding RNAs (lncRNAs), suggesting the ...
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39
Immunohistochemical study of the canonical and non ...
https://jcol.elsevier.es/en-immunohistochemical-study-canonical-non-canonical-wnt-articulo-S2237936315000556
Colorectal cancer is linked to several signaling pathways such as Wnt pathway. Our objective is to detect and verify the integrity of protein members of Wnt ...
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https://jcol.elsevier.es/en-immunohistochemical-study-canonical-non-canonical-wnt-articulo-S2237936315000556
Colorectal cancer is linked to several signaling pathways such as Wnt pathway. Our objective is to detect and verify the integrity of protein members of Wnt ...
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40
P085 Expression profiling of Wnt pathway genes in colon ...
https://www.ecco-ibd.eu/publications/congress-abstracts/item/p085-expression-profiling-of-wnt-pathway-genes-in-colon-biopsies-of-patients-with-ulcerative-colitis.html
There is an increasing demand of agents that can promote mucosal healing in Inflammatory Bowel Disease (IBD). Wnt/β-catenin signaling plays a critical role in ...
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https://www.ecco-ibd.eu/publications/congress-abstracts/item/p085-expression-profiling-of-wnt-pathway-genes-in-colon-biopsies-of-patients-with-ulcerative-colitis.html
There is an increasing demand of agents that can promote mucosal healing in Inflammatory Bowel Disease (IBD). Wnt/β-catenin signaling plays a critical role in ...
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41
Is resistant starch protective against colorectal cancer via ...
https://www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/is-resistant-starch-protective-against-colorectal-cancer-via-modulation-of-the-wnt-signalling-pathway/77CE672D5AF4448171B03D7AA5C53474
The WNT pathway is central to the maintenance of homeostasis within the large bowel through regulation of processes such as cell proliferation and migration ...
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https://www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/is-resistant-starch-protective-against-colorectal-cancer-via-modulation-of-the-wnt-signalling-pathway/77CE672D5AF4448171B03D7AA5C53474
The WNT pathway is central to the maintenance of homeostasis within the large bowel through regulation of processes such as cell proliferation and migration ...
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42
Wnt signaling suppresses MAPK-driven proliferation of ... - JCI
https://www.jci.org/articles/view/99325
The balance between proliferation and differentiation in intestinal stem cells (ISCs) is regulated by Wnt/β-catenin signaling, although the ...
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https://www.jci.org/articles/view/99325
The balance between proliferation and differentiation in intestinal stem cells (ISCs) is regulated by Wnt/β-catenin signaling, although the ...
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43
Modulation of Wnt Activity and Cell Physiology by Butyrate in ...
https://www.jcancer.org/v05p0203.htm
Dietary fiber intake is linked to a reduced risk of colon cancer. ... The effects of butyrate on Wnt signaling in colonic cells may be influenced by various ...
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https://www.jcancer.org/v05p0203.htm
Dietary fiber intake is linked to a reduced risk of colon cancer. ... The effects of butyrate on Wnt signaling in colonic cells may be influenced by various ...
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44
Small-molecule Wnt inhibitors are a potential novel therapy for ...
https://portlandpress.com/clinsci/article/136/19/1405/231861/Small-molecule-Wnt-inhibitors-are-a-potential
Intestinal fibrosis with stricture formation and associated bowel obstruction is a common and serious complication of Crohns disease (CD) [1]. Strictures occur ...
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https://portlandpress.com/clinsci/article/136/19/1405/231861/Small-molecule-Wnt-inhibitors-are-a-potential
Intestinal fibrosis with stricture formation and associated bowel obstruction is a common and serious complication of Crohns disease (CD) [1]. Strictures occur ...
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45
Tuning WNT-β-catenin signaling via BCL9 proteins for ...
https://www.thelancet.com/article/S2352-3964(15)00188-7/abstract
Colorectal cancer (CRC) cells frequently display a constitutively active WNT–β-catenin signaling pathway as a consequence of mutations in ...
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https://www.thelancet.com/article/S2352-3964(15)00188-7/abstract
Colorectal cancer (CRC) cells frequently display a constitutively active WNT–β-catenin signaling pathway as a consequence of mutations in ...
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46
NOTCH1 activates the Wnt/β-catenin signaling pathway in ...
https://www.oncotarget.com/article/19534/text/
On the other hand, reduction of NICD1 reduced luciferase activity of Wnt signaling pathway. In the 189 analyzed colon cancer cases, ...
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https://www.oncotarget.com/article/19534/text/
On the other hand, reduction of NICD1 reduced luciferase activity of Wnt signaling pathway. In the 189 analyzed colon cancer cases, ...
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47
Activation of the Wnt/β-Catenin Signaling Pathway Causes ...
https://www.redjournal.org/article/S0360-3016(19)31843-7/fulltext
Purpose/Objective(s). Most colorectal cancers are related to the inactivation of the adenomatous polyposis coli gene or β-catenin alteration.
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https://www.redjournal.org/article/S0360-3016(19)31843-7/fulltext
Purpose/Objective(s). Most colorectal cancers are related to the inactivation of the adenomatous polyposis coli gene or β-catenin alteration.
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48
The Wnt / Beta-Catenin Pathway and Familial Adenomatous ...
https://www.youtube.com/watch?v=I50ErVv8Iqs
Familial Adenomatous Polyposis (FAP) is an inherited genetic condition which predisposes individuals to the formation of colonic polyps.
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https://www.youtube.com/watch?v=I50ErVv8Iqs
Familial Adenomatous Polyposis (FAP) is an inherited genetic condition which predisposes individuals to the formation of colonic polyps.
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49
Wnt Signaling in Colon Cancer Stem Cells
https://novapublishers.com/shop/wnt-signaling-in-colon-cancer-stem-cells/
Wnt Signaling in Colon Cancer Stem Cells. $0.00 ... Colorectal cancer is the second leading cause of cancer-related death in the United States.
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https://novapublishers.com/shop/wnt-signaling-in-colon-cancer-stem-cells/
Wnt Signaling in Colon Cancer Stem Cells. $0.00 ... Colorectal cancer is the second leading cause of cancer-related death in the United States.
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50
The Wnt Pathway and its Role in Colorectal Cancer
https://www.targetedonc.com/view/dr-eckhardt-discusses-the-wnt-pathway
Clinical Pearls · The wnt pathway is highly mutated in colorectal cancer and has been linked to the regulation of the APC gene. · Since the wnt ...
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https://www.targetedonc.com/view/dr-eckhardt-discusses-the-wnt-pathway
Clinical Pearls · The wnt pathway is highly mutated in colorectal cancer and has been linked to the regulation of the APC gene. · Since the wnt ...
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51
WNT signaling in the normal intestine and colorectal cancer
https://www.imrpress.com/journal/FBL/12/2/10.2741/2076
The intestinal epithelium is a self-renewing tissue that represents a unique model for studying interconnected cellular processes such as ...
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https://www.imrpress.com/journal/FBL/12/2/10.2741/2076
The intestinal epithelium is a self-renewing tissue that represents a unique model for studying interconnected cellular processes such as ...
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52
Wnt Signalling Pathway - News Medical
https://www.news-medical.net/life-sciences/Wnt-Signalling-Pathway.aspx
Defective Wnt signalling is known to lead to several human pathologies, including cancer of the colon, breast and skin, skeletal effects and ...
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https://www.news-medical.net/life-sciences/Wnt-Signalling-Pathway.aspx
Defective Wnt signalling is known to lead to several human pathologies, including cancer of the colon, breast and skin, skeletal effects and ...
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53
Curcumin Effects on the Wnt Signaling Pathway in Colorectal ...
https://www.semanticscholar.org/paper/Curcumin-Effects-on-the-Wnt-Signaling-Pathway-in-Moradi-Marjaneh-Hassanian/9a825133a2aed86322ed6001d763f09a4bfe94c5
The relationship between Wnt-regulated CSCs and progression of CRC is described, and the efficacy of curcumin and its analogues in targeting colorectal C ...
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https://www.semanticscholar.org/paper/Curcumin-Effects-on-the-Wnt-Signaling-Pathway-in-Moradi-Marjaneh-Hassanian/9a825133a2aed86322ed6001d763f09a4bfe94c5
The relationship between Wnt-regulated CSCs and progression of CRC is described, and the efficacy of curcumin and its analogues in targeting colorectal C ...
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54
Development of Small Molecules Targeting the Wnt Signaling ...
https://www.clinical-colorectal-cancer.com/article/S1533-0028(15)00030-4/fulltext
In colorectal cancer (CRC), because of the abnormal cell growth and differentiation, these cells differentiate into mature cancer cells, and ...
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https://www.clinical-colorectal-cancer.com/article/S1533-0028(15)00030-4/fulltext
In colorectal cancer (CRC), because of the abnormal cell growth and differentiation, these cells differentiate into mature cancer cells, and ...
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55
WNT Signaling - Page 303 - Google Books Result
https://books.google.com/books?id=7WU6DwAAQBAJ&pg=PA303&lpg=PA303&dq=colon+wnt&source=bl&ots=TAc0EUkER0&sig=ACfU3U1wVRxylnjKK2BFgPHNAstF8sTMWA&hl=en&sa=X&ved=2ahUKEwjm6_uf8sr7AhVgXaQEHbPgBsEQ6AF6BQimAhAD
This has been particularly well documented for colon cancer18,19 (addressed further in Section 5). Several types of inhibitors of Wnt signaling are bone ¢de ...
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https://books.google.com/books?id=7WU6DwAAQBAJ&pg=PA303&lpg=PA303&dq=colon+wnt&source=bl&ots=TAc0EUkER0&sig=ACfU3U1wVRxylnjKK2BFgPHNAstF8sTMWA&hl=en&sa=X&ved=2ahUKEwjm6_uf8sr7AhVgXaQEHbPgBsEQ6AF6BQimAhAD
This has been particularly well documented for colon cancer18,19 (addressed further in Section 5). Several types of inhibitors of Wnt signaling are bone ¢de ...
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56
5 Interactions between MET and Wnt/β-catenin signaling in ...
https://www.researchgate.net/figure/Interactions-between-MET-and-Wnt-b-catenin-signaling-in-colon-cancer-stem-cells-a-In_fig5_322197224
Download scientific diagram | 5 Interactions between MET and Wnt/β-catenin signaling in colon cancer stem cells. (a) In the absence of Wnt ligand, ...
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https://www.researchgate.net/figure/Interactions-between-MET-and-Wnt-b-catenin-signaling-in-colon-cancer-stem-cells-a-In_fig5_322197224
Download scientific diagram | 5 Interactions between MET and Wnt/β-catenin signaling in colon cancer stem cells. (a) In the absence of Wnt ligand, ...
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57
Colon Cancer: New Insights for the Healthcare Professional: ...
https://books.google.com/books?id=Xr9HbNCWh5QC&pg=PA249&lpg=PA249&dq=colon+wnt&source=bl&ots=bbNwzsJU5a&sig=ACfU3U2lFmFfnsyGe_Fv8W9O5f4mE_BbMA&hl=en&sa=X&ved=2ahUKEwjm6_uf8sr7AhVgXaQEHbPgBsEQ6AF6BQinAhAD
Recently, it was reported that Bmi1 is a potential marker for intestinal stem cells. Because Wnt signaling plays a key role in intestinal stem cells, ...
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https://books.google.com/books?id=Xr9HbNCWh5QC&pg=PA249&lpg=PA249&dq=colon+wnt&source=bl&ots=bbNwzsJU5a&sig=ACfU3U2lFmFfnsyGe_Fv8W9O5f4mE_BbMA&hl=en&sa=X&ved=2ahUKEwjm6_uf8sr7AhVgXaQEHbPgBsEQ6AF6BQinAhAD
Recently, it was reported that Bmi1 is a potential marker for intestinal stem cells. Because Wnt signaling plays a key role in intestinal stem cells, ...
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Targeting the Wnt Pathway in Cancer - Page 59 - Google Books Result
https://books.google.com/books?id=Le3gUdUq_jsC&pg=PA59&lpg=PA59&dq=colon+wnt&source=bl&ots=5rBo9S3Ln3&sig=ACfU3U1oVBnm-EYNr0izvW_WiRxVlokiwA&hl=en&sa=X&ved=2ahUKEwjm6_uf8sr7AhVgXaQEHbPgBsEQ6AF6BQixAhAD
Just as EGFR was identified as a downstream target of Wnt, VEGF was found to be a downstream target in colon cancer cells and benign colonic adenomas (Zhang ...
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https://books.google.com/books?id=Le3gUdUq_jsC&pg=PA59&lpg=PA59&dq=colon+wnt&source=bl&ots=5rBo9S3Ln3&sig=ACfU3U1oVBnm-EYNr0izvW_WiRxVlokiwA&hl=en&sa=X&ved=2ahUKEwjm6_uf8sr7AhVgXaQEHbPgBsEQ6AF6BQixAhAD
Just as EGFR was identified as a downstream target of Wnt, VEGF was found to be a downstream target in colon cancer cells and benign colonic adenomas (Zhang ...
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59
Discovery could lead to new drugs to block protein that fuels ...
https://www.sciencedaily.com/releases/2022/11/221123114234.htm
In the last decade, scientists have developed drugs to block tankyrase in an attempt to treat bowel cancer -- but because Wnt signalling is ...
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https://www.sciencedaily.com/releases/2022/11/221123114234.htm
In the last decade, scientists have developed drugs to block tankyrase in an attempt to treat bowel cancer -- but because Wnt signalling is ...
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60
A growing role for beta-catenin in colon cancer | Broad Institute
https://www.broadinstitute.org/videos/growing-role-beta-catenin-colon-cancer
The Wnt/beta-catenin pathway is mutated in virtually all cases of colon cancer, but scientists have not been able to target it with drugs.
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https://www.broadinstitute.org/videos/growing-role-beta-catenin-colon-cancer
The Wnt/beta-catenin pathway is mutated in virtually all cases of colon cancer, but scientists have not been able to target it with drugs.
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61
A Low-Cost Drug From the 1960s Could Help ... - SciTechDaily
https://scitechdaily.com/a-low-cost-drug-from-the-1960s-could-help-treat-colon-cancer/
Reference: “Response to BRAF targeted therapy is enhanced by co-targeting VEGFRs or WNT/β-Catenin signaling in BRAF-mutant colorectal cancer ...
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https://scitechdaily.com/a-low-cost-drug-from-the-1960s-could-help-treat-colon-cancer/
Reference: “Response to BRAF targeted therapy is enhanced by co-targeting VEGFRs or WNT/β-Catenin signaling in BRAF-mutant colorectal cancer ...
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62
Colorectal cancer - Wikipedia
https://en.wikipedia.org/wiki/Colorectal_cancer
Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, ... mutations in the Wnt signaling pathway that increase signaling activity.
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https://en.wikipedia.org/wiki/Colorectal_cancer
Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, ... mutations in the Wnt signaling pathway that increase signaling activity.
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Cancer Stem Cells: Targeting the Roots of Cancer, Seeds of ...
https://books.google.com/books?id=JHL0CwAAQBAJ&pg=PA180&lpg=PA180&dq=colon+wnt&source=bl&ots=goMKr6mmnH&sig=ACfU3U3H1yjIEa7XYeoS92USt8nlQRsnoA&hl=en&sa=X&ved=2ahUKEwjm6_uf8sr7AhVgXaQEHbPgBsEQ6AF6BQi5AhAD
Like ISCs, colon CSCs have properties of both self-renewal and multilineage ... an intestinal Wnt/T-cell factor transcription factor signature gene set is ...
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https://books.google.com/books?id=JHL0CwAAQBAJ&pg=PA180&lpg=PA180&dq=colon+wnt&source=bl&ots=goMKr6mmnH&sig=ACfU3U3H1yjIEa7XYeoS92USt8nlQRsnoA&hl=en&sa=X&ved=2ahUKEwjm6_uf8sr7AhVgXaQEHbPgBsEQ6AF6BQi5AhAD
Like ISCs, colon CSCs have properties of both self-renewal and multilineage ... an intestinal Wnt/T-cell factor transcription factor signature gene set is ...
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Our Research - Ahmed Laboratory
https://ahmedgeneticslab.com/projects
Deregulation of Wnt signaling causes numerous birth defects and cancers, including nearly all colorectal cancers, the second leading cause of cancer-related ...
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https://ahmedgeneticslab.com/projects
Deregulation of Wnt signaling causes numerous birth defects and cancers, including nearly all colorectal cancers, the second leading cause of cancer-related ...
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Review - CORE
https://core.ac.uk/download/pdf/82118320.pdf
First, APC, the classically mutated genetic gate- keeper gene in colon cancer leading to Wnt pathway acti- vation (Kinzler and Vogelstein, 1996), can be ...
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https://core.ac.uk/download/pdf/82118320.pdf
First, APC, the classically mutated genetic gate- keeper gene in colon cancer leading to Wnt pathway acti- vation (Kinzler and Vogelstein, 1996), can be ...
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Anti-Proliferative Activity of Nodosin, a Diterpenoid from ...
http://wntproteins.com/anti-proliferative-activity-of-nodosin-a-diterpenoid-from-isodon-serra-via-regulation-of-wnt-%CE%B2-catenin-signaling-pathways-in-human-colon-cancer-cells/
Colorectal cancer (CRC) is one of the most malignant type of cancers and its ... Therefore, targeting Wnt/β-catenin signaling has been considered a crucial ...
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http://wntproteins.com/anti-proliferative-activity-of-nodosin-a-diterpenoid-from-isodon-serra-via-regulation-of-wnt-%CE%B2-catenin-signaling-pathways-in-human-colon-cancer-cells/
Colorectal cancer (CRC) is one of the most malignant type of cancers and its ... Therefore, targeting Wnt/β-catenin signaling has been considered a crucial ...
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67
Breakthrough paves way for new treatment of colon cancer
https://www.thebharatexpressnews.com/breakthrough-paves-way-for-new-treatment-of-colon-cancer/
“Almost all colon cancers have hyperactive Wnt signaling acting through tankyrase, and so they could potentially be treated with drugs that ...
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https://www.thebharatexpressnews.com/breakthrough-paves-way-for-new-treatment-of-colon-cancer/
“Almost all colon cancers have hyperactive Wnt signaling acting through tankyrase, and so they could potentially be treated with drugs that ...
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68
Controlling WNT Signaling Through DVL2
https://medschool.vanderbilt.edu/basic-sciences/2019/08/05/controlling-wnt-signaling-through-dvl2/
The WNT-PCP (planar cell polarity) pathway regulates tissue polarity and cell motility through its influence on actin dynamics. The protein ...
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https://medschool.vanderbilt.edu/basic-sciences/2019/08/05/controlling-wnt-signaling-through-dvl2/
The WNT-PCP (planar cell polarity) pathway regulates tissue polarity and cell motility through its influence on actin dynamics. The protein ...
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A Low-Cost Drug From The 1960s Could ... - Public News Time
https://publicnewstime.com/news/tech/a-low-cost-drug-from-the-1960s-could-help-treat-colon-cancer/
Reference: “Response to BRAF targeted therapy is enhanced by co-targeting VEGFRs or WNT/β-Catenin signaling in BRAF-mutant colorectal cancer ...
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https://publicnewstime.com/news/tech/a-low-cost-drug-from-the-1960s-could-help-treat-colon-cancer/
Reference: “Response to BRAF targeted therapy is enhanced by co-targeting VEGFRs or WNT/β-Catenin signaling in BRAF-mutant colorectal cancer ...
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Skin rash: Causes, 68 pictures of symptoms, and treatments
https://www.medicalnewstoday.com/articles/317999
Hookworm is a common intestinal parasite. It can cause a range of complications. ... Image credit: WNT. SIGN UP NOW. MEDICAL NEWS TODAY NEWSLETTER.
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https://www.medicalnewstoday.com/articles/317999
Hookworm is a common intestinal parasite. It can cause a range of complications. ... Image credit: WNT. SIGN UP NOW. MEDICAL NEWS TODAY NEWSLETTER.
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New research verifies TASINs as viable target for colon cancer ...
https://www.utsouthwestern.edu/newsroom/articles/year-2016/colon-cancer-target-shay.html
... to be a precursor to colon cancer, while sparing related normal cells, UT Southwestern Medical Center cancer biologists have demonstrated.
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https://www.utsouthwestern.edu/newsroom/articles/year-2016/colon-cancer-target-shay.html
... to be a precursor to colon cancer, while sparing related normal cells, UT Southwestern Medical Center cancer biologists have demonstrated.
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组蛋白脱乙酰酶2（HDAC2）基因- Gene - MCE
https://www.medchemexpress.cn/gene/3066.html
关联疾病 ; Colorectal Cancer. Colon Cancer. Colorectal Carcinoma. Colon Carcinoma. Colorectal Cancer, Susceptibility To. Carcinoma Of Colon. CRC.
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https://www.medchemexpress.cn/gene/3066.html
关联疾病 ; Colorectal Cancer. Colon Cancer. Colorectal Carcinoma. Colon Carcinoma. Colorectal Cancer, Susceptibility To. Carcinoma Of Colon. CRC.
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... smell is so strong. modavi: Y wld i wnt 2 know if my husband is a cheat? ... and mucus), and intestinal flora (bacteria and fungi). hi! my husband and i ...
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https://adaptare.me/my-husband-smells-bad.html
... smell is so strong. modavi: Y wld i wnt 2 know if my husband is a cheat? ... and mucus), and intestinal flora (bacteria and fungi). hi! my husband and i ...
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Prevalence of the Retro-Renal Colon: A Systematic Review and Meta-Analysis ... by Regulating Osteoblast Differentiation via Notch and Wnt/β-Catenin Pathways.
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https://www.dovepress.com/search_results.php?search_word=oral+care+market+in+saudi+arabia
Prevalence of the Retro-Renal Colon: A Systematic Review and Meta-Analysis ... by Regulating Osteoblast Differentiation via Notch and Wnt/β-Catenin Pathways.
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Visualization of cell signaling pathways. (2022) - Rainis
https://rainis.pics/article/visualization-of-cell-signaling-pathways
... ephrin B1 activates a non-canonical Wnt signaling pathway, also known as ... of ephrins in colon epithelial homeostasis and in colon cancer progression.
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https://rainis.pics/article/visualization-of-cell-signaling-pathways
... ephrin B1 activates a non-canonical Wnt signaling pathway, also known as ... of ephrins in colon epithelial homeostasis and in colon cancer progression.
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Colon Cancer Screening. ... Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer's Disease Model via Canonical Wnt/β-Catenin …
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https://online-courses.me/dr-b-patel.htm
Colon Cancer Screening. ... Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer's Disease Model via Canonical Wnt/β-Catenin …
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待确认 - 科研通
https://www.ablesci.com/assist/detail?id=qlLbN4
... Colon Cancer Cells · Role of Cancer Stem Cells of Breast, Colon, ... Hedgehog, and Wnt pathways in cancer stem cells: clinical update ...
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https://www.ablesci.com/assist/detail?id=qlLbN4
... Colon Cancer Cells · Role of Cancer Stem Cells of Breast, Colon, ... Hedgehog, and Wnt pathways in cancer stem cells: clinical update ...
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We found that KPV acts via PepT1 expressed in immune and intestinal epithelial cells. ... also known as Wnt-activated inhibitory factor 1 (WAIF1), ...
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Inflammatory bowel disease may benefit from the peptide. ... also known as Wnt-activated inhibitory factor 1 (WAIF1), encompassing amino acids 32-355. for ...
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