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Google Keyword Rankings for : why is mannitol given with cisplatin
1
Mannitol Prescribing Practices With Cisplatin Before and After ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551635/
Background Cisplatin-induced nephrotoxicity is a dose limiting adverse effect that occurs in nearly one-third of patients. Mannitol administration has been used ...
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551635/
Background Cisplatin-induced nephrotoxicity is a dose limiting adverse effect that occurs in nearly one-third of patients. Mannitol administration has been used ...
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2
Protective Effect of Mannitol on Cisplatin-Induced Nephrotoxicity
https://www.frontiersin.org/articles/10.3389/fonc.2021.804685/full
Cisplatin is a dose-limiting chemotherapeutic drug, primarily due to kidney injury. This explains why mannitol has a positive protective effect ...
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https://www.frontiersin.org/articles/10.3389/fonc.2021.804685/full
Cisplatin is a dose-limiting chemotherapeutic drug, primarily due to kidney injury. This explains why mannitol has a positive protective effect ...
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3
The Effect of Intravenous Mannitol Combined With Normal ...
https://ascopubs.org/doi/full/10.1200/GO.21.00275
Mannitol combined with hydration significantly prevented cisplatin-induced nephrotoxicity. Therefore, mannitol should be considered among ...
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https://ascopubs.org/doi/full/10.1200/GO.21.00275
Mannitol combined with hydration significantly prevented cisplatin-induced nephrotoxicity. Therefore, mannitol should be considered among ...
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4
The effect of mannitol addition to hydration on acute kidney ...
https://bmccancer.biomedcentral.com/articles/10.1186/s12885-022-09456-w
Saline hydration with addition of mannitol have commonly been the strategy to avoid cisplatin induced acute kidney injury (AKI).
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https://bmccancer.biomedcentral.com/articles/10.1186/s12885-022-09456-w
Saline hydration with addition of mannitol have commonly been the strategy to avoid cisplatin induced acute kidney injury (AKI).
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5
Mannitol dosing and cisplatin-induced acute nephrotoxicity
https://www.annalsofoncology.org/article/S0923-7534(19)45089-8/fulltext
Mannitol is an osmotic diuretic given routinely as part of cisplatin regimens to prevent nephrotoxicity. There are limited data on the ideal dose of mannitol.
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https://www.annalsofoncology.org/article/S0923-7534(19)45089-8/fulltext
Mannitol is an osmotic diuretic given routinely as part of cisplatin regimens to prevent nephrotoxicity. There are limited data on the ideal dose of mannitol.
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6
Hydration with magnesium and mannitol without furosemide ...
https://jtd.amegroups.com/article/view/620/html
Mannitol causes osmotic diuresis. Hayes and Frick revealed that mannitol decreased cisplatin nephrotoxicity (14,15). Clinically, mannitol reduces the urine ...
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https://jtd.amegroups.com/article/view/620/html
Mannitol causes osmotic diuresis. Hayes and Frick revealed that mannitol decreased cisplatin nephrotoxicity (14,15). Clinically, mannitol reduces the urine ...
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7
Administering Mannitol With Hydration and Premeds
https://www.oncologynurseadvisor.com/home/cancer-types/general-oncology/administering-mannitol-with-hydration-and-premeds/
Mannitol is an osmotic diuretic that increases urine output. It may be used before cisplatin to reduce the nephrotoxic effects of cisplatin. Not ...
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https://www.oncologynurseadvisor.com/home/cancer-types/general-oncology/administering-mannitol-with-hydration-and-premeds/
Mannitol is an osmotic diuretic that increases urine output. It may be used before cisplatin to reduce the nephrotoxic effects of cisplatin. Not ...
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8
Mannitol for Chemo Side-effects:Cisplatin-Induced Kidney Injury
https://addon.life/2021/08/13/mannitol-chemo-side-effects/
Clinical studies have shown that using mannitol along with Cisplatin chemotherapy reduces Cisplatin-induced kidney injury, an adverse side- ...
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https://addon.life/2021/08/13/mannitol-chemo-side-effects/
Clinical studies have shown that using mannitol along with Cisplatin chemotherapy reduces Cisplatin-induced kidney injury, an adverse side- ...
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9
Cisplatin nephrotoxicity - UpToDate
https://www.uptodate.com/contents/cisplatin-nephrotoxicity
› contents › cisplatin-nephro...
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https://www.uptodate.com/contents/cisplatin-nephrotoxicity
› contents › cisplatin-nephro...
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10
CP-136 Mannitol 10% for the prevention of cisplatin induced ...
https://ejhp.bmj.com/content/24/Suppl_1/A61.1
Background Cisplatin induced nephrotoxicity is a dose limiting adverse effect that occurs in nearly one-third of patients. Mannitol administration has been ...
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https://ejhp.bmj.com/content/24/Suppl_1/A61.1
Background Cisplatin induced nephrotoxicity is a dose limiting adverse effect that occurs in nearly one-third of patients. Mannitol administration has been ...
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11
The Nephroprotective Effect of Mannitol in Head and Neck ...
https://journals.sagepub.com/doi/full/10.1177/1179554918821320
Mannitol, which causes osmotic diuresis, has also been found to help decrease cisplatin nephrotoxicity. Clinically, mannitol reduces the urine concentration of ...
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https://journals.sagepub.com/doi/full/10.1177/1179554918821320
Mannitol, which causes osmotic diuresis, has also been found to help decrease cisplatin nephrotoxicity. Clinically, mannitol reduces the urine concentration of ...
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12
Effect of mannitol on acute kidney injury induced by cisplatin
https://link.springer.com/article/10.1007/s00520-020-05703-7
Recent studies suggested that mannitol has a protective effect against cisplatin-induced nephrotoxicity for high-dose cisplatin used in head and ...
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https://link.springer.com/article/10.1007/s00520-020-05703-7
Recent studies suggested that mannitol has a protective effect against cisplatin-induced nephrotoxicity for high-dose cisplatin used in head and ...
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13
Cisplatin 1 mg/ml Sterile Concentrate - print friendly - (emc)
https://www.medicines.org.uk/emc/product/3788/smpc/print
The administration of mannitol or a diuretic is also required when the administrated cisplatin dose is higher than 60 mg/m2 of body surface. It is necessary ...
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https://www.medicines.org.uk/emc/product/3788/smpc/print
The administration of mannitol or a diuretic is also required when the administrated cisplatin dose is higher than 60 mg/m2 of body surface. It is necessary ...
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14
The Effect of Intravenous Mannitol Plus Saline on the ...
https://www.clinicaltrials.gov/ct2/show/NCT04251689
Brief Summary: This study include cancer patients who had received chemotherapy that include cisplatin. Patients were randomly assigned to either a mannitol 20 ...
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https://www.clinicaltrials.gov/ct2/show/NCT04251689
Brief Summary: This study include cancer patients who had received chemotherapy that include cisplatin. Patients were randomly assigned to either a mannitol 20 ...
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15
Evidence in Patients Receiving Cisplatin Therapy | ONS
https://www.ons.org/cjon/22/2/nephrotoxicity-evidence-patients-receiving-cisplatin-therapy
Seven studies evaluated the effect of mannitol on cisplatin-related nephrotoxicity. Three trials found no clear indication that mannitol is nephroprotective ...
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https://www.ons.org/cjon/22/2/nephrotoxicity-evidence-patients-receiving-cisplatin-therapy
Seven studies evaluated the effect of mannitol on cisplatin-related nephrotoxicity. Three trials found no clear indication that mannitol is nephroprotective ...
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16
The Effect of Mannitol Addition on Hydration in Acute Kidney ...
https://www.researchsquare.com/article/rs-643773/latest.pdf
Keywords: High dose cisplatin, mannitol, acute kidney injury ... Mannitol is better given for patients who receive < 75mg/m2 in terms of ...
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https://www.researchsquare.com/article/rs-643773/latest.pdf
Keywords: High dose cisplatin, mannitol, acute kidney injury ... Mannitol is better given for patients who receive < 75mg/m2 in terms of ...
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17
Hydration with Mannitol and Dextrose May Promote Cisplatin ...
https://www.hindawi.com/journals/jt/2021/5547341/
Backgrounds. Cisplatin (CP) still is a novel choice for solid tumor therapy, but it is accompanied with the side effect of nephrotoxicity. Hydration may reduce ...
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https://www.hindawi.com/journals/jt/2021/5547341/
Backgrounds. Cisplatin (CP) still is a novel choice for solid tumor therapy, but it is accompanied with the side effect of nephrotoxicity. Hydration may reduce ...
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18
The role of mannitol as a nephroprotectant in patients ...
https://www.themednet.org/publications/the-role-of-mannitol-as-a-nephroprotectant-in-patients-receiving-cisplatin-therapy
Mannitol plus hydration has been used for several years to alleviate toxicity associated with cisplatin therapy. However, the data for mannitol administration ...
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https://www.themednet.org/publications/the-role-of-mannitol-as-a-nephroprotectant-in-patients-receiving-cisplatin-therapy
Mannitol plus hydration has been used for several years to alleviate toxicity associated with cisplatin therapy. However, the data for mannitol administration ...
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19
[PDF] The effect of mannitol addition to hydration on acute ...
https://www.researchgate.net/publication/359907500_The_effect_of_mannitol_addition_to_hydration_on_acute_kidney_injury_event_after_high_dose_cisplatin_chemotherapy_an_ambispective_cohort_study
Background: Mannitol is an osmotic diuretic given routinely as part of cisplatin regimens to prevent nephrotoxicity, but there are limited data ...
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https://www.researchgate.net/publication/359907500_The_effect_of_mannitol_addition_to_hydration_on_acute_kidney_injury_event_after_high_dose_cisplatin_chemotherapy_an_ambispective_cohort_study
Background: Mannitol is an osmotic diuretic given routinely as part of cisplatin regimens to prevent nephrotoxicity, but there are limited data ...
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20
Randomized study comparing mannitol with furosemide for ...
https://onlinelibrary.wiley.com/doi/full/10.1111/ajco.13423
We compared the cisplatin-induced nephrotoxicity prevention effect of f. ... of mannitol are available, it should preferentially be given to ...
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https://onlinelibrary.wiley.com/doi/full/10.1111/ajco.13423
We compared the cisplatin-induced nephrotoxicity prevention effect of f. ... of mannitol are available, it should preferentially be given to ...
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21
Manipulating the Blood Labyrinth Barrier with Mannitol to ...
https://www.sciencedirect.com/science/article/abs/pii/S0378595522002143
Cisplatin, a chemotherapeutic medication, remains in the cochlea indefinitely, causing permanent hearing loss. Mannitol, a diuretic medication, ...
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https://www.sciencedirect.com/science/article/abs/pii/S0378595522002143
Cisplatin, a chemotherapeutic medication, remains in the cochlea indefinitely, causing permanent hearing loss. Mannitol, a diuretic medication, ...
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22
High-dose cisplatin therapy using mannitol versus furosemide ...
https://europepmc.org/article/med/6784924
The dose-limiting toxic effect of high-dose (100 mg/m2) cisplatin is renal insufficiency. Hydration with furosemide- or mannitol-induced diuresis has been ...
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https://europepmc.org/article/med/6784924
The dose-limiting toxic effect of high-dose (100 mg/m2) cisplatin is renal insufficiency. Hydration with furosemide- or mannitol-induced diuresis has been ...
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23
Cancer Medicine Journal - TRIDHA Scholars
https://www.tridhascholars.org/pdfs/mannitol-for-the-prevention-of-cisplatin-induced-nephrotoxicity-a-prospective-comparison-of-hydration-plus-mannitol-versus-hydration-alone-in-the-military-hospital-in-tunisia-CMJ-S2-1001.pdf
Mannitol for the Prevention of Cisplatin-Induced Nephrotoxicity: A ... treatment duration up to a month after the last given dose.
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https://www.tridhascholars.org/pdfs/mannitol-for-the-prevention-of-cisplatin-induced-nephrotoxicity-a-prospective-comparison-of-hydration-plus-mannitol-versus-hydration-alone-in-the-military-hospital-in-tunisia-CMJ-S2-1001.pdf
Mannitol for the Prevention of Cisplatin-Induced Nephrotoxicity: A ... treatment duration up to a month after the last given dose.
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24
A case–control study analyzing mannitol dosing for prevention ...
https://www.semanticscholar.org/paper/A-case%E2%80%93control-study-analyzing-mannitol-dosing-for-Dhillon-Amir/aa309888445c21f85ed0dc51b13db3845a69c8d0
Cisplatin-induced acute nephrotoxicity remains common in patients with good baseline renal function despite preventive measures, ...
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https://www.semanticscholar.org/paper/A-case%E2%80%93control-study-analyzing-mannitol-dosing-for-Dhillon-Amir/aa309888445c21f85ed0dc51b13db3845a69c8d0
Cisplatin-induced acute nephrotoxicity remains common in patients with good baseline renal function despite preventive measures, ...
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25
DRUG NAME: Cisplatin - BC Cancer
http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Cisplatin_monograph.pdf
mannitol, or furosemide-induced diuresis is used to effectively decrease ... doses of cisplatin are given with less intensive hydration.
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http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Cisplatin_monograph.pdf
mannitol, or furosemide-induced diuresis is used to effectively decrease ... doses of cisplatin are given with less intensive hydration.
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26
High Dose Cisplatin with Mannitol-Induced
https://www.karger.com/Article/Pdf/393348
A phase II clinical trial of high dose cisplatin with mannitol induced diuresis was conducted in patients with biopsy proven advanced lung cancer presenting ...
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https://www.karger.com/Article/Pdf/393348
A phase II clinical trial of high dose cisplatin with mannitol induced diuresis was conducted in patients with biopsy proven advanced lung cancer presenting ...
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27
Mannitol Prescribing Practices With Cisplatin Before and After ...
https://dc.etsu.edu/cgi/viewcontent.cgi?article=3420&context=etsu-works
benefit of mannitol use in preventing cisplatin-induced ... Given that higher doses (>75 mg/m2) of cisplatin were not.
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https://dc.etsu.edu/cgi/viewcontent.cgi?article=3420&context=etsu-works
benefit of mannitol use in preventing cisplatin-induced ... Given that higher doses (>75 mg/m2) of cisplatin were not.
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28
CISplatin Injection DESCRIPTION CLINICAL PHARMACOLOGY
https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/018057s083lbl.pdf
Over a dose range of 40 to 140 mg cisplatin/m2 given as a bolus injection or ... to 8-hour infusion with intravenous hydration, and mannitol has been used.
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https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/018057s083lbl.pdf
Over a dose range of 40 to 140 mg cisplatin/m2 given as a bolus injection or ... to 8-hour infusion with intravenous hydration, and mannitol has been used.
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29
Effect of forced diuresis with mannitol on renal function during ...
https://abstracts.ncri.org.uk/abstract/effect-of-forced-diuresis-with-mannitol-on-renal-function-during-cisplatin-chemotherapy-2/
Patients given mannitol (for insufficient diuresis) were more likely to stop cisplatin for renal failure after cycle 1 (8.2% v 2.2%, p=0.045).
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https://abstracts.ncri.org.uk/abstract/effect-of-forced-diuresis-with-mannitol-on-renal-function-during-cisplatin-chemotherapy-2/
Patients given mannitol (for insufficient diuresis) were more likely to stop cisplatin for renal failure after cycle 1 (8.2% v 2.2%, p=0.045).
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30
study protocol for a randomised controlled trial | BMJ Open
https://dx.doi.org/10.1136/bmjopen-2019-029057
Introduction Cisplatin (CDDP) is a key drug for various thoracic malignancies. To avoid renal toxicity of CDDP, mannitol is routinely used, but it sometimes ...
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https://dx.doi.org/10.1136/bmjopen-2019-029057
Introduction Cisplatin (CDDP) is a key drug for various thoracic malignancies. To avoid renal toxicity of CDDP, mannitol is routinely used, but it sometimes ...
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31
Short Hydration in Chemotherapy Containing Cisplatin (≥75 ...
https://academic.oup.com/jjco/article/43/11/1105/834654
Immediately before the administration of cisplatin, mannitol (20%, ... All the patients gave their written informed consent.
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https://academic.oup.com/jjco/article/43/11/1105/834654
Immediately before the administration of cisplatin, mannitol (20%, ... All the patients gave their written informed consent.
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32
Prevention and management of cisplatin nephrotoxicity - eviQ
https://www.eviq.org.au/clinical-resources/side-effect-and-toxicity-management/prophylaxis-and-treatment/184-prevention-and-management-of-cisplatin-nephrot
Many years of experience at one centre using a low dose of 10 mmol (2.74 g) per dose of cisplatin has not resulted in any symptomatic hypomagnesaemia. Mannitol.
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https://www.eviq.org.au/clinical-resources/side-effect-and-toxicity-management/prophylaxis-and-treatment/184-prevention-and-management-of-cisplatin-nephrot
Many years of experience at one centre using a low dose of 10 mmol (2.74 g) per dose of cisplatin has not resulted in any symptomatic hypomagnesaemia. Mannitol.
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33
Cisplatin (chemotherapy drug) - treatment and side effects
https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/cisplatin
Cisplatin can affect the kidneys. You will be given extra fluids through the drip before and after the cisplatin. You may also have a drug called mannitol.
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https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/cisplatin
Cisplatin can affect the kidneys. You will be given extra fluids through the drip before and after the cisplatin. You may also have a drug called mannitol.
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34
CISPLATIN INJECTION
https://labeling.pfizer.com/ShowLabeling.aspx?id=12140
1 mg/mL, mannitol 1 mg/mL and sodium chloride 9 mg/mL in water for injections. The ... Cisplatin is recommended to be given once every 3-4 weeks.
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https://labeling.pfizer.com/ShowLabeling.aspx?id=12140
1 mg/mL, mannitol 1 mg/mL and sodium chloride 9 mg/mL in water for injections. The ... Cisplatin is recommended to be given once every 3-4 weeks.
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35
Cisplatin-Platinol-AQ® - GlobalRPH
https://globalrph.com/oncology/cisplatin-platinol-aq/
The drug is then diluted in 2 liters of 5% Dextrose in 1/2 or 1/3 normal saline containing 37.5 g of mannitol, and infused over a 6- to 8- hour ...
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https://globalrph.com/oncology/cisplatin-platinol-aq/
The drug is then diluted in 2 liters of 5% Dextrose in 1/2 or 1/3 normal saline containing 37.5 g of mannitol, and infused over a 6- to 8- hour ...
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36
COMPARISON OF MAGNESIUM AND MANNITOL ...
http://docs.neu.edu.tr/library/8898045867.pdf
“Comparison of Magnesium and Mannitol preloading on Cisplatin-induced ... given lifetime dosage restrictions (also known as cumulative dose).
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http://docs.neu.edu.tr/library/8898045867.pdf
“Comparison of Magnesium and Mannitol preloading on Cisplatin-induced ... given lifetime dosage restrictions (also known as cumulative dose).
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37
Manipulating the Blood Labyrinth Barrier with ... - TSpace
https://tspace.library.utoronto.ca/handle/1807/103291
Mannitol injections at t=6 hours reduced cisplatin ototoxicity and enhanced the efficacy of antioxidants. This will provide an important therapeutic strategy to ...
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https://tspace.library.utoronto.ca/handle/1807/103291
Mannitol injections at t=6 hours reduced cisplatin ototoxicity and enhanced the efficacy of antioxidants. This will provide an important therapeutic strategy to ...
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38
Cisplatin (UK PID) - INCHEM
https://inchem.org/documents/ukpids/ukpids/ukpid21.htm
The formulation also contains sodium chloride and mannitol. ... With multiple drug schedules cisplatin is usually given in doses from 20 mg/m2 upward every ...
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https://inchem.org/documents/ukpids/ukpids/ukpid21.htm
The formulation also contains sodium chloride and mannitol. ... With multiple drug schedules cisplatin is usually given in doses from 20 mg/m2 upward every ...
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39
CSPM2 Hydration Protocol for Cisplatin Chemotherapy
http://www.wales.nhs.uk/sites3/Documents/456/IV%20Hydration%20for%20Cisplatin%20final%2007.15.pdf
provides better renal protection than sodium chloride 0.9% plus mannitol. Cisplatin and magnesium affect the same sodium and water channels ...
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http://www.wales.nhs.uk/sites3/Documents/456/IV%20Hydration%20for%20Cisplatin%20final%2007.15.pdf
provides better renal protection than sodium chloride 0.9% plus mannitol. Cisplatin and magnesium affect the same sodium and water channels ...
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40
Thoracic malignancies, cisplatin and renal function
https://erj.ersjournals.com/content/37/4/760
by J Nortier · 2011 · Cited by 5 —
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https://erj.ersjournals.com/content/37/4/760
by J Nortier · 2011 · Cited by 5 —
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41
Saline, mannitol, and furosemide hydration in acute cisplatin ...
https://search.proquest.com/openview/289b9ba9ddcae2f497ccf237b6e3726a/1.pdf?pq-origsite=gscholar&cbl=48447
+ furosemide arm, 40 mg of furosemide was given after hydration. In the saline + mannitol arm, 50 g of man- nitol was mixed with the cisplatin.
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https://search.proquest.com/openview/289b9ba9ddcae2f497ccf237b6e3726a/1.pdf?pq-origsite=gscholar&cbl=48447
+ furosemide arm, 40 mg of furosemide was given after hydration. In the saline + mannitol arm, 50 g of man- nitol was mixed with the cisplatin.
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42
Cisplatin dosing, indications, interactions, adverse effects, and ...
https://reference.medscape.com/drug/platinol-aq-cisplatin-342108
It is a chemotherapy drug that contains platinum. It is used to slow or stop cancer cell growth. HOW TO USE: This medication is usually given by injection into ...
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https://reference.medscape.com/drug/platinol-aq-cisplatin-342108
It is a chemotherapy drug that contains platinum. It is used to slow or stop cancer cell growth. HOW TO USE: This medication is usually given by injection into ...
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43
DBL Cisplatin Data Sheet - Medsafe
https://www.medsafe.govt.nz/profs/datasheet/d/DBLCisplatininj.pdf
A repeat course of cisplatin should not be given until: ... pretreatment hydration or after the hydration, 375 mL of 10% mannitol injection may.
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https://www.medsafe.govt.nz/profs/datasheet/d/DBLCisplatininj.pdf
A repeat course of cisplatin should not be given until: ... pretreatment hydration or after the hydration, 375 mL of 10% mannitol injection may.
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44
CBOP/BEP - NHS England
https://www.england.nhs.uk/south/wp-content/uploads/sites/6/2018/11/CBOP-BEP.pdf
Do not give more than a single dose of either furosemide or mannitol without discussing with consultant. Cisplatin. 500mL. 1 hour. Sodium Chloride 0.9% + 2g ...
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https://www.england.nhs.uk/south/wp-content/uploads/sites/6/2018/11/CBOP-BEP.pdf
Do not give more than a single dose of either furosemide or mannitol without discussing with consultant. Cisplatin. 500mL. 1 hour. Sodium Chloride 0.9% + 2g ...
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45
Reduction in nephrotoxicities using short hydration for ...
https://www.esmoopen.com/article/S2059-7029(20)32298-5/fulltext
Conventional hydration (CH) in chemotherapy containing cisplatin (CDDP) has been recommended to prevent renal toxicity. Although an increasing number of ...
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https://www.esmoopen.com/article/S2059-7029(20)32298-5/fulltext
Conventional hydration (CH) in chemotherapy containing cisplatin (CDDP) has been recommended to prevent renal toxicity. Although an increasing number of ...
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46
THOR – PEMEtrexed + CISplatin (NSCLC)
https://www.cancercare.mb.ca/export/sites/default/For-Health-Professionals/.galleries/files/treatment-guidelines-rro-files/regimen-reference-orders/thoracic/THOR-PEMEtrexed-CISplatin-NSCLC.pdf
*Alert: CISplatin infusion must be complete prior to mannitol ... *Alert: The last dose of vitamin B12 will be given either 3 weeks,.
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https://www.cancercare.mb.ca/export/sites/default/For-Health-Professionals/.galleries/files/treatment-guidelines-rro-files/regimen-reference-orders/thoracic/THOR-PEMEtrexed-CISplatin-NSCLC.pdf
*Alert: CISplatin infusion must be complete prior to mannitol ... *Alert: The last dose of vitamin B12 will be given either 3 weeks,.
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47
ANALYSIS OF NACL-MANNITOL HYDRATION ON RENAL ...
https://e-journal.unair.ac.id/FMI/article/view/5492
Cisplatin nephrotoxicity can be prevented by aggressive hydration or alternate method of administration. The aim of this study was to analyze ...
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https://e-journal.unair.ac.id/FMI/article/view/5492
Cisplatin nephrotoxicity can be prevented by aggressive hydration or alternate method of administration. The aim of this study was to analyze ...
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48
Nephroprotection by Theophylline in Patients with Cisplatin ...
https://jasn.asnjournals.org/content/jnephrol/early/2004/12/08/ASN.2004030225.full.pdf
Written informed consent was given by each ... sium and 6.9 mmol of calcium per 24 h and mannitol, 250 ml (20%),.
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https://jasn.asnjournals.org/content/jnephrol/early/2004/12/08/ASN.2004030225.full.pdf
Written informed consent was given by each ... sium and 6.9 mmol of calcium per 24 h and mannitol, 250 ml (20%),.
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49
Risk Factors for Cisplatin-Induced Nephrotoxicity and ... - PLOS
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101902
The development of hypomagnesemia during cisplatin treatment was ... However, given that magnesium supplementation has not been accepted as ...
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101902
The development of hypomagnesemia during cisplatin treatment was ... However, given that magnesium supplementation has not been accepted as ...
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50
Cisplatin and Gemcitabine – NSCLC - SWAG Cancer Alliance
https://www.swagcanceralliance.nhs.uk/wp-content/uploads/2020/09/Cisplatin-Gemcitabine-NSCLC.pdf
Mannitol 10%. 400mL. 15 minutes. Ensure urine output > 100mL / hour prior to giving cisplatin. Give a single dose of furosemide 20mg iv if necessary.
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https://www.swagcanceralliance.nhs.uk/wp-content/uploads/2020/09/Cisplatin-Gemcitabine-NSCLC.pdf
Mannitol 10%. 400mL. 15 minutes. Ensure urine output > 100mL / hour prior to giving cisplatin. Give a single dose of furosemide 20mg iv if necessary.
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51
Stress response inhibits the nephrotoxicity of cisplatin
https://journals.physiology.org/doi/full/10.1152/ajprenal.00041.2003
Patients treated with cisplatin are generally given up to 6 l saline/day iv (28, 34). The diuretic mannitol is also commonly used to decrease the ...
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https://journals.physiology.org/doi/full/10.1152/ajprenal.00041.2003
Patients treated with cisplatin are generally given up to 6 l saline/day iv (28, 34). The diuretic mannitol is also commonly used to decrease the ...
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52
Cisplatin: Package Insert / Prescribing Information - Drugs.com
https://www.drugs.com/pro/cisplatin.html
In these reports, Cisplatin for injection was generally given in ... 50 mg Cisplatin, 450 mg Sodium Chloride, USP, and 500 mg Mannitol, USP.
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https://www.drugs.com/pro/cisplatin.html
In these reports, Cisplatin for injection was generally given in ... 50 mg Cisplatin, 450 mg Sodium Chloride, USP, and 500 mg Mannitol, USP.
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53
Mannitol: Uses, Interactions, Mechanism of Action - DrugBank
https://go.drugbank.com/drugs/DB00742
Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol ...
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https://go.drugbank.com/drugs/DB00742
Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol ...
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54
CISPLATIN - Fresenius Kabi USA
http://editor.fresenius-kabi.us/PIs/Cisplatin_Inj_45628C_Jan_08.pdf
Cisplatin Injection is a sterile aqueous solution ... dosage, cisplatin should not be given more fre- ... with intravenous hydration, and mannitol has.
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http://editor.fresenius-kabi.us/PIs/Cisplatin_Inj_45628C_Jan_08.pdf
Cisplatin Injection is a sterile aqueous solution ... dosage, cisplatin should not be given more fre- ... with intravenous hydration, and mannitol has.
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55
Cisplatin Flashcards - Quizlet
https://quizlet.com/410740516/cisplatin-flash-cards/
Mannitol. Is mannitol given before, during, or after the administration of Cisplatin? before. What test should be obtained prior to treatment? audiogram.
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https://quizlet.com/410740516/cisplatin-flash-cards/
Mannitol. Is mannitol given before, during, or after the administration of Cisplatin? before. What test should be obtained prior to treatment? audiogram.
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56
The Renal Clearance of Unchanged Cisplatin during ...
https://jpharmsci.org/article/S0022-3549(15)50088-9/abstract
Compared with furosemide, mannitol showed greater modification in Clr of unchanged CDDP in the early phase and more accelerated urinary excretion of unchanged ...
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https://jpharmsci.org/article/S0022-3549(15)50088-9/abstract
Compared with furosemide, mannitol showed greater modification in Clr of unchanged CDDP in the early phase and more accelerated urinary excretion of unchanged ...
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57
BRA_64_Nattiya.pdf
http://www.rcpt.org/abstractdb/media/abstract/CON2018/Best%20Resident27/BRA_64_Nattiya.pdf
Mannitol to Prevent Renal Toxicity in Non-small. Cell Lung Cancer (NSCLC) Patients Receiving. Cisplatin-gemcitabine Chemotherapy.
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http://www.rcpt.org/abstractdb/media/abstract/CON2018/Best%20Resident27/BRA_64_Nattiya.pdf
Mannitol to Prevent Renal Toxicity in Non-small. Cell Lung Cancer (NSCLC) Patients Receiving. Cisplatin-gemcitabine Chemotherapy.
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58
Cisplatin: Delivering a Safe Infusion - jstor
https://www.jstor.org/stable/3424881
many anticancer drugs, cisplatin ... The drug may be given ... Toxicity becomes more severe * Add prescribed amount of mannitol.
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https://www.jstor.org/stable/3424881
many anticancer drugs, cisplatin ... The drug may be given ... Toxicity becomes more severe * Add prescribed amount of mannitol.
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59
Osmotic Diuretics Induce Adenosine A1 Receptor Expression ...
https://www.jbc.org/article/S0021-9258(20)77071-7/pdf
Osmotic diuretic agents, such as mannitol are used in the ... tic agent, cisplatin, in the proximal tubular epithelial cells.
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https://www.jbc.org/article/S0021-9258(20)77071-7/pdf
Osmotic diuretic agents, such as mannitol are used in the ... tic agent, cisplatin, in the proximal tubular epithelial cells.
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60
cisPlatin cheMotheraPy orders - Lee Health
https://www.leehealth.org/getmedia/6088906e-52d5-4780-98ac-be3d5395ba79/3042ChemotherapyCisplatin.pdf
CISplatin if urine output is less than 300 mL for 2 hours give Furosemide (Lasix) 20 mg IV Push. Repeat ... Mannitol 12.5 gm IV to be added to CISplatin bag.
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https://www.leehealth.org/getmedia/6088906e-52d5-4780-98ac-be3d5395ba79/3042ChemotherapyCisplatin.pdf
CISplatin if urine output is less than 300 mL for 2 hours give Furosemide (Lasix) 20 mg IV Push. Repeat ... Mannitol 12.5 gm IV to be added to CISplatin bag.
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61
Effect of mannitol on acute kidney injury induced by cisplatin.
http://search.ebscohost.com/login.aspx?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=09414355&AN=148804054&h=OiMmOaS3MyGx0s0dxPcRgF8Qx6WtjII7gFnepJ33htWIL9jJh07CfhKJHz7ZH4F5bn706z9mFCNlt%2FvU8IbFHA%3D%3D&crl=c
No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. Copyright ...
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http://search.ebscohost.com/login.aspx?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=09414355&AN=148804054&h=OiMmOaS3MyGx0s0dxPcRgF8Qx6WtjII7gFnepJ33htWIL9jJh07CfhKJHz7ZH4F5bn706z9mFCNlt%2FvU8IbFHA%3D%3D&crl=c
No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. Copyright ...
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62
NCCP Chemotherapy Regimen - ) + Etoposide Therapy-21 day
https://www.hse.ie/eng/services/list/5/cancer/profinfo/chemoprotocols/lung/280.pdf
aThe total dose of CISplatin may be fractionated and given over 3 days i.e. ... Administer 200 mL of mannitol 20% over 15 minutes*(near the ...
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https://www.hse.ie/eng/services/list/5/cancer/profinfo/chemoprotocols/lung/280.pdf
aThe total dose of CISplatin may be fractionated and given over 3 days i.e. ... Administer 200 mL of mannitol 20% over 15 minutes*(near the ...
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63
Cisplatin Injection - RxList
https://www.rxlist.com/cisplatin-drug.htm
Care must be taken to avoid inadvertent cisplatin (cisplatin injection) overdose ... containing 37.5 g of mannitol, and infused over a 6- to 8- hour period.
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https://www.rxlist.com/cisplatin-drug.htm
Care must be taken to avoid inadvertent cisplatin (cisplatin injection) overdose ... containing 37.5 g of mannitol, and infused over a 6- to 8- hour period.
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64
Risk analysis for cisplatin-induced nephrotoxicity during first ...
https://e-century.us/files/ijcem/9/2/ijcem0017104.pdf
Mannitol should therefore not be included in intravenous hydration. In addition, as the number of risk ... Given that cisplatin is predominantly excreted.
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https://e-century.us/files/ijcem/9/2/ijcem0017104.pdf
Mannitol should therefore not be included in intravenous hydration. In addition, as the number of risk ... Given that cisplatin is predominantly excreted.
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65
CISplatin | CHEO ED Outreach
https://outreach.cheo.on.ca/manual/1517
CISplatin · Available as a 1 mg/mL solution. Protect from light · Vial stable 7 days at room temperature. · Use only IV sets and needles which do not contain ...
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https://outreach.cheo.on.ca/manual/1517
CISplatin · Available as a 1 mg/mL solution. Protect from light · Vial stable 7 days at room temperature. · Use only IV sets and needles which do not contain ...
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66
P1.03-014 Saline Alone vs Saline plus Mannitol Hydration for ...
https://www.jto.org/article/S1556-0864(17)31553-8/fulltext
Cisplatin is widely used as an effective chemotherapy in diverse neoplasms and is associated with renal toxicity. Several studies suggest that pre-hydration ...
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https://www.jto.org/article/S1556-0864(17)31553-8/fulltext
Cisplatin is widely used as an effective chemotherapy in diverse neoplasms and is associated with renal toxicity. Several studies suggest that pre-hydration ...
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67
Handbook of Cancer Chemotherapy - Page 89 - Google Books Result
https://books.google.com/books?id=CG8HLvx3IlAC&pg=PA89&lpg=PA89&dq=why+is+mannitol+given+with+cisplatin&source=bl&ots=C8TXNukTpP&sig=ACfU3U10UUyp2egtUA1x4uOtDIJstPR4bA&hl=en&sa=X&ved=2ahUKEwiN9aSrq8v7AhXLlIkEHaa3AQYQ6AF6BQiqAhAD
After 1 h of infusion , give 12.5 g of mannitol by IV push . c . Immediately thereafter , start the cisplatin ( mixed in normal saline at 1 mg / mL ) and ...
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https://books.google.com/books?id=CG8HLvx3IlAC&pg=PA89&lpg=PA89&dq=why+is+mannitol+given+with+cisplatin&source=bl&ots=C8TXNukTpP&sig=ACfU3U10UUyp2egtUA1x4uOtDIJstPR4bA&hl=en&sa=X&ved=2ahUKEwiN9aSrq8v7AhXLlIkEHaa3AQYQ6AF6BQiqAhAD
After 1 h of infusion , give 12.5 g of mannitol by IV push . c . Immediately thereafter , start the cisplatin ( mixed in normal saline at 1 mg / mL ) and ...
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68
Principles and Practice of Gynecologic Oncology
https://books.google.com/books?id=KW9esgo759EC&pg=PA500&lpg=PA500&dq=why+is+mannitol+given+with+cisplatin&source=bl&ots=SMTwe4zu5a&sig=ACfU3U2UVIi93lYqgyGcwzyuqrLQ8hPnfA&hl=en&sa=X&ved=2ahUKEwiN9aSrq8v7AhXLlIkEHaa3AQYQ6AF6BQisAhAD
With adequate hydration and mannitol diuresis to prevent nephrotoxicity ... The ratio of cisplatin to total free platinum in plasma has a great deal of ...
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https://books.google.com/books?id=KW9esgo759EC&pg=PA500&lpg=PA500&dq=why+is+mannitol+given+with+cisplatin&source=bl&ots=SMTwe4zu5a&sig=ACfU3U2UVIi93lYqgyGcwzyuqrLQ8hPnfA&hl=en&sa=X&ved=2ahUKEwiN9aSrq8v7AhXLlIkEHaa3AQYQ6AF6BQisAhAD
With adequate hydration and mannitol diuresis to prevent nephrotoxicity ... The ratio of cisplatin to total free platinum in plasma has a great deal of ...
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69
Oncology - Cisplatin (Platinol) - Pharmacology 2000
https://www.pharmacology2000.com/Oncology/oncology431.htm
Cisplatin (Platinol), as well as carboplatin and oxaliplatin initiate their ... organoplatinum antineoplastic drugs exhibit bifunctionality given that they ...
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https://www.pharmacology2000.com/Oncology/oncology431.htm
Cisplatin (Platinol), as well as carboplatin and oxaliplatin initiate their ... organoplatinum antineoplastic drugs exhibit bifunctionality given that they ...
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70
The ability of mannitol to decrease cisplatin-induced ...
https://www.urotoday.com/pediatric-urology/85042-the-ability-of-mannitol-to-decrease-cisplatin-induced-nephrotoxicity-in-children-real-or-not.html
METHODS - The main pharmacodynamics and clinical characteristics of cisplatin nephrotoxicity are described in order to explore the real ability ...
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https://www.urotoday.com/pediatric-urology/85042-the-ability-of-mannitol-to-decrease-cisplatin-induced-nephrotoxicity-in-children-real-or-not.html
METHODS - The main pharmacodynamics and clinical characteristics of cisplatin nephrotoxicity are described in order to explore the real ability ...
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71
The role of mannitol as a nephroprotectant in ... - Sigma-Aldrich
https://www.sigmaaldrich.com/AR/en/tech-docs/paper/450762
Mannitol plus hydration has been used for several years to alleviate toxicity associated with cisplatin therapy. However, the data for mannitol ...
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https://www.sigmaaldrich.com/AR/en/tech-docs/paper/450762
Mannitol plus hydration has been used for several years to alleviate toxicity associated with cisplatin therapy. However, the data for mannitol ...
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72
Find Product details - Jan Aushadhi
http://janaushadhi.gov.in/productlist.aspx
136, 153, Cisplatin Injection IP 10 mg per10ml, Vial, 35.00. 137, 154, Cisplatin Injection BP ... 145, 170, Mannitol Injection IP 20% w/v, 100 ml, 28.00.
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http://janaushadhi.gov.in/productlist.aspx
136, 153, Cisplatin Injection IP 10 mg per10ml, Vial, 35.00. 137, 154, Cisplatin Injection BP ... 145, 170, Mannitol Injection IP 20% w/v, 100 ml, 28.00.
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73
Medicinal Chemistry-II | B Pharmacy Notes - Carewell Pharma
https://www.carewellpharma.in/B_Pharmacy/Notes/5th_Sem/Medicinal_Chemistry-II/
... Vinblastin sulphate, Vincristin sulphate. Miscellaneous: Cisplatin, Mitotane. ... Osmotic Diuretics: Mannitol. Anti-hypertensive Agents:.
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https://www.carewellpharma.in/B_Pharmacy/Notes/5th_Sem/Medicinal_Chemistry-II/
... Vinblastin sulphate, Vincristin sulphate. Miscellaneous: Cisplatin, Mitotane. ... Osmotic Diuretics: Mannitol. Anti-hypertensive Agents:.
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74
Protective Effect of Mannitol on Cisplatin-Induced Nephrotoxicity
https://www.readcube.com/articles/10.3389/fonc.2021.804685
inflammatory process of cisplatin-induced kidney injury. ... evidence to prove this effect. ... mannitol has nephroprotective effects that have not proven (37).
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https://www.readcube.com/articles/10.3389/fonc.2021.804685
inflammatory process of cisplatin-induced kidney injury. ... evidence to prove this effect. ... mannitol has nephroprotective effects that have not proven (37).
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75
Cisplatin-Associated Nephrotoxic Effects in Children
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2765680
Cisplatin has been an important component of chemotherapy for cure and control of several pediatric and adult malignant tumors.
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https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2765680
Cisplatin has been an important component of chemotherapy for cure and control of several pediatric and adult malignant tumors.
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76
The Chemotherapy Source Book - Page 157 - Google Books Result
https://books.google.com/books?id=CDADMzS0TKUC&pg=PA157&lpg=PA157&dq=why+is+mannitol+given+with+cisplatin&source=bl&ots=dPje6p2MKU&sig=ACfU3U09PQ0Es-O9_TrzSqiSksqo5K5rBQ&hl=en&sa=X&ved=2ahUKEwiN9aSrq8v7AhXLlIkEHaa3AQYQ6AF6BQirAhAD
One patient ( 90 ) clearly had an HSR to mannitol ( given to promote osmotic diuresis ) administered just before cisplatin was to be infused .
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https://books.google.com/books?id=CDADMzS0TKUC&pg=PA157&lpg=PA157&dq=why+is+mannitol+given+with+cisplatin&source=bl&ots=dPje6p2MKU&sig=ACfU3U09PQ0Es-O9_TrzSqiSksqo5K5rBQ&hl=en&sa=X&ved=2ahUKEwiN9aSrq8v7AhXLlIkEHaa3AQYQ6AF6BQirAhAD
One patient ( 90 ) clearly had an HSR to mannitol ( given to promote osmotic diuresis ) administered just before cisplatin was to be infused .
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77
Principles and Practice of Gynecologic Oncology
https://books.google.com/books?id=hsMne5mAXSIC&pg=PA418&lpg=PA418&dq=why+is+mannitol+given+with+cisplatin&source=bl&ots=-18WjlOMMi&sig=ACfU3U28VSL4HnHt1QKG0DoaQ7Qmc9uYVA&hl=en&sa=X&ved=2ahUKEwiN9aSrq8v7AhXLlIkEHaa3AQYQ6AF6BQiuAhAD
If cisplatin is administered in a hospital setting, patients should receive hydration with 1 to 2 L of fluid prior to cisplatin. Mannitol diuresis is ...
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https://books.google.com/books?id=hsMne5mAXSIC&pg=PA418&lpg=PA418&dq=why+is+mannitol+given+with+cisplatin&source=bl&ots=-18WjlOMMi&sig=ACfU3U28VSL4HnHt1QKG0DoaQ7Qmc9uYVA&hl=en&sa=X&ved=2ahUKEwiN9aSrq8v7AhXLlIkEHaa3AQYQ6AF6BQiuAhAD
If cisplatin is administered in a hospital setting, patients should receive hydration with 1 to 2 L of fluid prior to cisplatin. Mannitol diuresis is ...
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78
Cancer Treatment Reports
https://books.google.com/books?id=rS7jFdy5hV0C&pg=PA33&lpg=PA33&dq=why+is+mannitol+given+with+cisplatin&source=bl&ots=8hkZj27VLP&sig=ACfU3U2-P-nrmG8OpvWKbUMQ4xI14J9vcw&hl=en&sa=X&ved=2ahUKEwiN9aSrq8v7AhXLlIkEHaa3AQYQ6AF6BQiwAhAD
... 2-4 > 4 Cisplatin Cisplatin + mannitol Moderate Moderate LifethreatSevere ... No. of patients . compared to 11 patients given cisplatin plus mannitol .
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https://books.google.com/books?id=rS7jFdy5hV0C&pg=PA33&lpg=PA33&dq=why+is+mannitol+given+with+cisplatin&source=bl&ots=8hkZj27VLP&sig=ACfU3U2-P-nrmG8OpvWKbUMQ4xI14J9vcw&hl=en&sa=X&ved=2ahUKEwiN9aSrq8v7AhXLlIkEHaa3AQYQ6AF6BQiwAhAD
... 2-4 > 4 Cisplatin Cisplatin + mannitol Moderate Moderate LifethreatSevere ... No. of patients . compared to 11 patients given cisplatin plus mannitol .
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79
Which action is an appropriate nursing intervention for a ...
https://frojeostern.com/which-action-is-an-appropriate-nursing-intervention-for-a-patient-who-is-taking-hydrochlorothiazide
› which-action-is-an-appropriate...
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https://frojeostern.com/which-action-is-an-appropriate-nursing-intervention-for-a-patient-who-is-taking-hydrochlorothiazide
› which-action-is-an-appropriate...
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80
Saline Alone vs Saline plus Mannitol Hydration for the ... - DTIC
https://apps.dtic.mil/sti/citations/AD1040828
Cisplatin is widely used as an effective chemotherapy in diverse neoplasms and is associated with renal toxicity. Several studies suggest that pre-hydration ...
→ Check Latest Keyword Rankings ←
https://apps.dtic.mil/sti/citations/AD1040828
Cisplatin is widely used as an effective chemotherapy in diverse neoplasms and is associated with renal toxicity. Several studies suggest that pre-hydration ...
→ Check Latest Keyword Rankings ←
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