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Google Keyword Rankings for : methyl mismatch repair
1
Mechanisms and functions of DNA mismatch repair - Nature
https://www.nature.com/articles/cr2007115
DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability.
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https://www.nature.com/articles/cr2007115
DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability.
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2
DNA mismatch repair - Wikipedia
https://en.wikipedia.org/wiki/DNA_mismatch_repair
DNA mismatch repair (MMR) is a system for recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA ...
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https://en.wikipedia.org/wiki/DNA_mismatch_repair
DNA mismatch repair (MMR) is a system for recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA ...
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3
Mismatch Repair Animation - YouTube
https://www.youtube.com/watch?v=AgdMnMMbc8Q
Shomu's Biology Academy
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https://www.youtube.com/watch?v=AgdMnMMbc8Q
Shomu's Biology Academy
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4
Mismatch repair - YouTube
https://www.youtube.com/watch?v=41AJ1CFSqKA
Shomu's Biology
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https://www.youtube.com/watch?v=41AJ1CFSqKA
Shomu's Biology
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5
DNA Mismatch repair - YouTube
https://www.youtube.com/watch?v=wukucowb8sA
Quick Biochemistry Basics
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https://www.youtube.com/watch?v=wukucowb8sA
Quick Biochemistry Basics
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6
Video 7.2 Methyl-Directed Mismatch Repair - Learning Link
https://learninglink.oup.com/access/content/cooper8e-student-resources/cooper8e-chapter-7-video-2
› access › content
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https://learninglink.oup.com/access/content/cooper8e-student-resources/cooper8e-chapter-7-video-2
› access › content
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7
Mismatch Repair Pathway - Creative Diagnostics
https://www.creative-diagnostics.com/mismatch-repair-pathway.htm
DNA mismatch repair (MMR) recognizes and repairs erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA replication and ...
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https://www.creative-diagnostics.com/mismatch-repair-pathway.htm
DNA mismatch repair (MMR) recognizes and repairs erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA replication and ...
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8
Deficiency of replication-independent DNA mismatch repair ...
https://www.science.org/doi/10.1126/sciadv.abg4398
DNA mismatch repair (MMR) is a highly conserved DNA repair pathway, well known for its ability to recognize and remove errors from the newly ...
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https://www.science.org/doi/10.1126/sciadv.abg4398
DNA mismatch repair (MMR) is a highly conserved DNA repair pathway, well known for its ability to recognize and remove errors from the newly ...
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9
DNA Mismatch Repair in Eukaryotes and Bacteria - Hindawi
https://www.hindawi.com/journals/jna/2010/260512/
DNA mismatch repair (MMR) corrects mismatched base pairs mainly caused by DNA replication errors. The fundamental mechanisms and proteins involved in the ...
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https://www.hindawi.com/journals/jna/2010/260512/
DNA mismatch repair (MMR) corrects mismatched base pairs mainly caused by DNA replication errors. The fundamental mechanisms and proteins involved in the ...
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10
Mismatch Repair Pathway, Genome Stability and Cancer
https://www.frontiersin.org/articles/10.3389/fmolb.2020.00122/full
The main job of the DNA mismatch repair system is to correct spontaneous base–base mispairs and small insertions–deletion loops (indels) that ...
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https://www.frontiersin.org/articles/10.3389/fmolb.2020.00122/full
The main job of the DNA mismatch repair system is to correct spontaneous base–base mispairs and small insertions–deletion loops (indels) that ...
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11
Mismatch repair-dependent processing of methylation ...
http://genesdev.cshlp.org/content/21/24/3342
O6-Methylguanine (MeG) is a highly cytotoxic DNA modification generated by SN1-type methylating agents. Despite numerous studies implicating DNA replication, ...
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http://genesdev.cshlp.org/content/21/24/3342
O6-Methylguanine (MeG) is a highly cytotoxic DNA modification generated by SN1-type methylating agents. Despite numerous studies implicating DNA replication, ...
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12
DNA mismatch repair in the context of chromatin
https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-020-0379-7
DNA mismatch repair (MMR) maintains replication fidelity by correcting mispaired nucleotides incorporated by DNA polymerases.
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https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-020-0379-7
DNA mismatch repair (MMR) maintains replication fidelity by correcting mispaired nucleotides incorporated by DNA polymerases.
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13
Methyl-directed DNA Mismatch Correction
https://www.jbc.org/article/S0021-9258(18)83467-6/pdf
pair mismatches within recombination intermediates as the basis for gene conversion. The existence of the mismatch repair systems im- plied by this proposal is ...
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https://www.jbc.org/article/S0021-9258(18)83467-6/pdf
pair mismatches within recombination intermediates as the basis for gene conversion. The existence of the mismatch repair systems im- plied by this proposal is ...
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14
DNA proofreading and repair (article) | Khan Academy
https://www.khanacademy.org/science/biology/dna-as-the-genetic-material/dna-replication/a/dna-proofreading-and-repair
Immediately after DNA synthesis, any remaining mispaired bases can be detected and replaced in a process called mismatch repair. If DNA gets damaged, it can be ...
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https://www.khanacademy.org/science/biology/dna-as-the-genetic-material/dna-replication/a/dna-proofreading-and-repair
Immediately after DNA synthesis, any remaining mispaired bases can be detected and replaced in a process called mismatch repair. If DNA gets damaged, it can be ...
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15
DNA mismatch repair system
https://febs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1742-4658.2006.05190.x
Subsequent studies on the roles of MMR proteins in response to. DNA damage in normal cells showed that N-methyl-. N¢-nitro-N-nitrosoguanidine, ...
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https://febs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1742-4658.2006.05190.x
Subsequent studies on the roles of MMR proteins in response to. DNA damage in normal cells showed that N-methyl-. N¢-nitro-N-nitrosoguanidine, ...
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16
MED1, a novel human methyl-CpG-binding endonuclease ...
https://www.pnas.org/doi/10.1073/pnas.96.7.3969
The DNA mismatch repair (MMR) is a specialized system, highly conserved throughout evolution, involved in the maintenance of genomic integrity.
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https://www.pnas.org/doi/10.1073/pnas.96.7.3969
The DNA mismatch repair (MMR) is a specialized system, highly conserved throughout evolution, involved in the maintenance of genomic integrity.
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17
Different base/base mismatches are corrected with different ...
https://www.cell.com/abstract/0092-8674(84)90283-6
Methyl-directed DNA mismatch repair was lost completely for any type of mismatch in strains carrying either mutL or mutS mutations. Data obtained with a mutH ...
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https://www.cell.com/abstract/0092-8674(84)90283-6
Methyl-directed DNA mismatch repair was lost completely for any type of mismatch in strains carrying either mutL or mutS mutations. Data obtained with a mutH ...
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18
Deficiency in DNA mismatch repair of methylation damage is a ...
https://www.biorxiv.org/content/10.1101/2020.11.18.388108v1.full
DNA mismatch repair (MMR) is essential for maintaining genome integrity with its deficiency predisposing to cancer. MMR is well known for its ...
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https://www.biorxiv.org/content/10.1101/2020.11.18.388108v1.full
DNA mismatch repair (MMR) is essential for maintaining genome integrity with its deficiency predisposing to cancer. MMR is well known for its ...
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19
Methyl-directed Mismatch Repair - Mheducation - McGraw Hill
https://highered.mheducation.com/sites/9834092339/student_view0/chapter14/methyl-directed_mismatch_repair.html
2. In methyl-directed mismatch repair, the strand that is repaired is. A ...
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https://highered.mheducation.com/sites/9834092339/student_view0/chapter14/methyl-directed_mismatch_repair.html
2. In methyl-directed mismatch repair, the strand that is repaired is. A ...
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20
Mismatch Repair-Dependent Transcriptome Changes In ...
https://aacrjournals.org/cancerres/article/63/23/8158/510862/Mismatch-Repair-Dependent-Transcriptome-Changes-In
DNA mismatch repair (MMR) plays a key role in the cytotoxic response of human cells to methylating agents, however, the cascade of events ...
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https://aacrjournals.org/cancerres/article/63/23/8158/510862/Mismatch-Repair-Dependent-Transcriptome-Changes-In
DNA mismatch repair (MMR) plays a key role in the cytotoxic response of human cells to methylating agents, however, the cascade of events ...
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21
Escherichia coli K-12 substr. MG1655 MutHLS complex ...
https://biocyc.org/ECOLI/NEW-IMAGE?type=ENZYME&object=MUTHLS-CPLX
The methyl-directed mismatch repair system (also known as the MutHLS-dependent mismatch repair system) recognizes most base-base mispairs, as well as mismatches ...
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https://biocyc.org/ECOLI/NEW-IMAGE?type=ENZYME&object=MUTHLS-CPLX
The methyl-directed mismatch repair system (also known as the MutHLS-dependent mismatch repair system) recognizes most base-base mispairs, as well as mismatches ...
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22
DNA mismatch repair and DNA methylation in adult brain ...
https://www.jneurosci.org/content/16/3/939
We focused on the repair of G.T and G.U mismatches, which are caused by deamination of 5-methyl cytosine to thymine, or cytosine to uracil, ...
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https://www.jneurosci.org/content/16/3/939
We focused on the repair of G.T and G.U mismatches, which are caused by deamination of 5-methyl cytosine to thymine, or cytosine to uracil, ...
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23
MECHANISMS AND BIOLOGICAL EFFECTS OF MISMATCH ...
https://www.annualreviews.org/doi/pdf/10.1146/annurev.ge.25.120191.001305
The most interesting of the bacterial mismatch repair systems, from the point of view of both mechanism and biology, are the E. coli methyl-directed.
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https://www.annualreviews.org/doi/pdf/10.1146/annurev.ge.25.120191.001305
The most interesting of the bacterial mismatch repair systems, from the point of view of both mechanism and biology, are the E. coli methyl-directed.
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24
Methyl-directed mismatch repair is bidirectional.
https://scholars.duke.edu/display/pub753161
Methyl-directed mismatch repair is initiated by the mismatch-provoked, MutHLS-dependent cleavage of the unmodified strand at a ...
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https://scholars.duke.edu/display/pub753161
Methyl-directed mismatch repair is initiated by the mismatch-provoked, MutHLS-dependent cleavage of the unmodified strand at a ...
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25
Quiz & Worksheet - Mismatch Repair in DNA Replication
https://study.com/academy/practice/quiz-worksheet-mismatch-repair-in-dna-replication.html
The nucleotides in the DNA backbone will be damaged. · There will be a bump in the DNA backbone. · Methyl groups will attach to the error site on the DNA backbone ...
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https://study.com/academy/practice/quiz-worksheet-mismatch-repair-in-dna-replication.html
The nucleotides in the DNA backbone will be damaged. · There will be a bump in the DNA backbone. · Methyl groups will attach to the error site on the DNA backbone ...
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26
mismatch repair | biochemistry - Britannica
https://www.britannica.com/science/mismatch-repair
…important mechanism is that of mismatch repair, which has been studied extensively in E. coli. The system is directed by the presence of a methyl group ...
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https://www.britannica.com/science/mismatch-repair
…important mechanism is that of mismatch repair, which has been studied extensively in E. coli. The system is directed by the presence of a methyl group ...
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27
Mismatch Repair: From Preserving Genome Stability to ... - MDPI
https://mdpi-res.com/d_attachment/cells/cells-10-01535/article_deploy/cells-10-01535-v2.pdf?version=1624331909
Keywords: mismatch repair; DNA replication errors; recombination; ... methyl-directed mismatch repair in Escherichia coli.
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https://mdpi-res.com/d_attachment/cells/cells-10-01535/article_deploy/cells-10-01535-v2.pdf?version=1624331909
Keywords: mismatch repair; DNA replication errors; recombination; ... methyl-directed mismatch repair in Escherichia coli.
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28
1AZO: DNA MISMATCH REPAIR PROTEIN MUTH FROM E ...
https://www.rcsb.org/structure/1azo
MutS, MutL and MutH are the three essential proteins for initiation of methyl-directed DNA mismatch repair to correct mistakes made during DNA replication ...
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https://www.rcsb.org/structure/1azo
MutS, MutL and MutH are the three essential proteins for initiation of methyl-directed DNA mismatch repair to correct mistakes made during DNA replication ...
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29
Methylator-induced, Mismatch Repair-dependent G2 Arrest Is ...
https://www.molbiolcell.org/doi/10.1091/mbc.e04-02-0089
The nitrosourea N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) is a well characterized monofunctional DNA alkylating agent. The cytotoxic and mutagenic potential ...
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https://www.molbiolcell.org/doi/10.1091/mbc.e04-02-0089
The nitrosourea N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) is a well characterized monofunctional DNA alkylating agent. The cytotoxic and mutagenic potential ...
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30
Mismatch Repair: Notes | Draw it to Know it
https://drawittoknowit.com/course/pathology/biology/cell-cycle/1213/mismatch-repair/notes
Mismatch repair: identifies/fixes replication errors that escape DNA Pol. · MutS recognizes mismatched base and initiates repair by binding · MutS forms complex ...
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https://drawittoknowit.com/course/pathology/biology/cell-cycle/1213/mismatch-repair/notes
Mismatch repair: identifies/fixes replication errors that escape DNA Pol. · MutS recognizes mismatched base and initiates repair by binding · MutS forms complex ...
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31
Inefficient mismatch repair: genetic defects and down regulation
https://link.springer.com/article/10.1007/BF02994699
The mismatch repair system is involved in the maintenance of genomic integrity by editing DNA replication and recombination.
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https://link.springer.com/article/10.1007/BF02994699
The mismatch repair system is involved in the maintenance of genomic integrity by editing DNA replication and recombination.
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32
Paul Modrich - Nobel Lecture
https://www.nobelprize.org/uploads/2018/06/modrich-lecture.pdf
coli methyl-directed mismatch repair. Page 3. Mechanisms in E. coli and Human Mismatch Repair. 101 helix directs mismatch ...
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https://www.nobelprize.org/uploads/2018/06/modrich-lecture.pdf
coli methyl-directed mismatch repair. Page 3. Mechanisms in E. coli and Human Mismatch Repair. 101 helix directs mismatch ...
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33
Mismatch Repair Balances Leading and Lagging Strand DNA ...
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1003016
This mismatch is flanked by an AT-rich triplet repeat sequence that, when interrupted, restores MMR to >95% efficiency. Thus this natural DNA ...
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https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1003016
This mismatch is flanked by an AT-rich triplet repeat sequence that, when interrupted, restores MMR to >95% efficiency. Thus this natural DNA ...
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34
Chapter 12: DNA Damage and Repair – Chemistry
https://wou.edu/chemistry/courses/online-chemistry-textbooks/ch450-and-ch451-biochemistry-defining-life-at-the-molecular-level/chapter-12-dna-damage-repair-and-mutations/
DNA mismatch repair (MMR) is a highly conserved DNA repair system (Table 12.2) that greatly contributes to maintain genome stability through the correction of ...
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https://wou.edu/chemistry/courses/online-chemistry-textbooks/ch450-and-ch451-biochemistry-defining-life-at-the-molecular-level/chapter-12-dna-damage-repair-and-mutations/
DNA mismatch repair (MMR) is a highly conserved DNA repair system (Table 12.2) that greatly contributes to maintain genome stability through the correction of ...
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35
5.2: DNA Repair - Biology LibreTexts
https://bio.libretexts.org/Bookshelves/Biochemistry/Book%3A_Biochemistry_Free_and_Easy_(Ahern_and_Rajagopal)/05%3A_Flow_of_Genetic_Information/5.02%3A_DNA_Repair
Because methylation is the criterion that enables the mismatch repair system to choose the strand that is repaired, the bacterial mismatch ...
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https://bio.libretexts.org/Bookshelves/Biochemistry/Book%3A_Biochemistry_Free_and_Easy_(Ahern_and_Rajagopal)/05%3A_Flow_of_Genetic_Information/5.02%3A_DNA_Repair
Because methylation is the criterion that enables the mismatch repair system to choose the strand that is repaired, the bacterial mismatch ...
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36
Mismatch Repair Assay | Springer Nature Experiments
https://experiments.springernature.com/articles/10.1385/1-59259-675-4:121
Defects in mismatch repair have also been identified as an important route to tolerance of certain cytotoxic methylating agents (reviewed in 4).
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https://experiments.springernature.com/articles/10.1385/1-59259-675-4:121
Defects in mismatch repair have also been identified as an important route to tolerance of certain cytotoxic methylating agents (reviewed in 4).
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37
Mutagenesis and DNA repair - ATDBio
https://atdbio.com/nucleic-acids-book/Mutagenesis-and-DNA-repair
Mismatches generally destabilize the DNA duplex and give local melting, or opening up, of the double helix, to promote base flipping; and this is one mechanism ...
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https://atdbio.com/nucleic-acids-book/Mutagenesis-and-DNA-repair
Mismatches generally destabilize the DNA duplex and give local melting, or opening up, of the double helix, to promote base flipping; and this is one mechanism ...
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38
Competency in mismatch repair prohibits clonal expansion of ...
https://www.jci.org/articles/view/118767
Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N'-nitro-N-nitrosoguanidine. J M Carethers, M T Hawn, ...
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https://www.jci.org/articles/view/118767
Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N'-nitro-N-nitrosoguanidine. J M Carethers, M T Hawn, ...
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39
Methyl directed mismatch repair | By All About Molecular Biology
https://m.facebook.com/AAMB.DZ/videos/methyl-directed-mismatch-repair/2024478610902432/
All About Molecular Biology
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https://m.facebook.com/AAMB.DZ/videos/methyl-directed-mismatch-repair/2024478610902432/
All About Molecular Biology
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40
Repair Of Mutations - Repair Of Dna - MCAT Content
https://jackwestin.com/resources/mcat-content/repair-of-dna/repair-of-mutations
Mismatch repair can also correct small insertions and deletions that happen when the DNA polymerase slips on a template. If a mismatch error occurs, a protein ...
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https://jackwestin.com/resources/mcat-content/repair-of-dna/repair-of-mutations
Mismatch repair can also correct small insertions and deletions that happen when the DNA polymerase slips on a template. If a mismatch error occurs, a protein ...
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41
DNA mismatch repair genes and colorectal cancer - Gut
https://gut.bmj.com/content/47/1/148
In HNPCC, a germline mutation (usually in hMLH1 or hMSH2) is accompanied by one further event (usually allelic loss) to inactivate a mismatch repair gene. In ...
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https://gut.bmj.com/content/47/1/148
In HNPCC, a germline mutation (usually in hMLH1 or hMSH2) is accompanied by one further event (usually allelic loss) to inactivate a mismatch repair gene. In ...
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42
Crosstalk between mismatch repair and base ... - Oncotarget
https://www.oncotarget.com/article/10185/text/
DNA repair gene expression in a set of gastric cancers suggested an inverse association between the expression of the mismatch repair (MMR) ...
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https://www.oncotarget.com/article/10185/text/
DNA repair gene expression in a set of gastric cancers suggested an inverse association between the expression of the mismatch repair (MMR) ...
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43
Spatiotemporal Manipulation of the Mismatch Repair System ...
https://pubs.acs.org/doi/10.1021/acssynbio.1c00031
(a) The bacterial DNA mismatch repair (MMR) system recognizes and fixes ... through manipulating its methyl-directed mismatch repair system.
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https://pubs.acs.org/doi/10.1021/acssynbio.1c00031
(a) The bacterial DNA mismatch repair (MMR) system recognizes and fixes ... through manipulating its methyl-directed mismatch repair system.
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44
Atomic Force Microscopy Captures the Initiation of ... - UNCG
https://libres.uncg.edu/ir/uncg//listing.aspx?styp=ti&id=32697
Atomic Force Microscopy Captures the Initiation of Methyl-Directed DNA Mismatch Repair. UNCG Author/Contributor (non-UNCG co-authors, ...
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https://libres.uncg.edu/ir/uncg//listing.aspx?styp=ti&id=32697
Atomic Force Microscopy Captures the Initiation of Methyl-Directed DNA Mismatch Repair. UNCG Author/Contributor (non-UNCG co-authors, ...
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45
Animation 9.3 DNA Repair Mechanisms: Methyl Mismatch ...
https://quizlet.com/74309537/animation-93-dna-repair-mechanisms-methyl-mismatch-repair-flash-cards/
The methyl directed mismatch repair proteins and genes are called Mut because strands that are defective in one of these proteins have a high mutation rate. A ...
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https://quizlet.com/74309537/animation-93-dna-repair-mechanisms-methyl-mismatch-repair-flash-cards/
The methyl directed mismatch repair proteins and genes are called Mut because strands that are defective in one of these proteins have a high mutation rate. A ...
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46
DNA Mismatch Repair Protein MutH
http://earth.callutheran.edu/Academic_Programs/Departments/BioDev/omm/muth/frames/muthtxt.htm
Figure 1 depicts the role of MutH, MutS, and MutL in methyl-directed mismatch repair. Once MutS, another mismatch repair protein, recognizes an error and ...
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http://earth.callutheran.edu/Academic_Programs/Departments/BioDev/omm/muth/frames/muthtxt.htm
Figure 1 depicts the role of MutH, MutS, and MutL in methyl-directed mismatch repair. Once MutS, another mismatch repair protein, recognizes an error and ...
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47
MutL involvement in two DNA repair pathways: methyl ...
https://cdr.lib.unc.edu/concern/dissertations/js956h15h?locale=en
MutL is an essential component of the Escherichia coli mismatch repair (MMR) pathway and has been shown to interact with nearly every protein involved in the ...
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https://cdr.lib.unc.edu/concern/dissertations/js956h15h?locale=en
MutL is an essential component of the Escherichia coli mismatch repair (MMR) pathway and has been shown to interact with nearly every protein involved in the ...
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48
Role of Postreplicative DNA Mismatch Repair in the ... - JSTOR
https://www.jstor.org/stable/2899545
After incorporation into DNA, the thioguanine is chemically methylated by S-adenosylmethionine to form S6-methylthioguanine. During DNA replication, the S6- ...
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https://www.jstor.org/stable/2899545
After incorporation into DNA, the thioguanine is chemically methylated by S-adenosylmethionine to form S6-methylthioguanine. During DNA replication, the S6- ...
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49
Schematic representation of methyl‐directed DNA mismatch ...
https://www.researchgate.net/figure/Schematic-representation-of-methyl-directed-DNA-mismatch-repair-in-E-coli-Only-the-5-0_fig1_6896103
... The MutH cleaves the GATC sites of the unmethylated strand, removing the daughter DNA strand. Repair of the mismatch is completed with the synthesis of new ...
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https://www.researchgate.net/figure/Schematic-representation-of-methyl-directed-DNA-mismatch-repair-in-E-coli-Only-the-5-0_fig1_6896103
... The MutH cleaves the GATC sites of the unmethylated strand, removing the daughter DNA strand. Repair of the mismatch is completed with the synthesis of new ...
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50
Atomic force microscopy captures the initiation ... - Sigma-Aldrich
https://www.sigmaaldrich.com/ZA/en/tech-docs/paper/649495
Atomic force microscopy captures the initiation of methyl-directed DNA mismatch repair. DNA repair (2015-10-16). Eric A Josephs, Tianli Zheng, ...
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https://www.sigmaaldrich.com/ZA/en/tech-docs/paper/649495
Atomic force microscopy captures the initiation of methyl-directed DNA mismatch repair. DNA repair (2015-10-16). Eric A Josephs, Tianli Zheng, ...
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51
Repair of naturally occurring mismatches can induce ... - eLife
https://elifesciences.org/articles/02001
'Normal' genomic DNA contains hundreds of mismatches that are generated daily by the spontaneous deamination of C (U/G) and methyl-C (T/G).
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https://elifesciences.org/articles/02001
'Normal' genomic DNA contains hundreds of mismatches that are generated daily by the spontaneous deamination of C (U/G) and methyl-C (T/G).
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52
Mismatch repair, genetic stability and tumour avoidance
https://royalsocietypublishing.org/doi/10.1098/rstb.1995.0014
Escherischia coli methyl-directed mismatch repair eliminates premutagenic lesions that arise via DNA biosynthetic errors; components of the repair system ...
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https://royalsocietypublishing.org/doi/10.1098/rstb.1995.0014
Escherischia coli methyl-directed mismatch repair eliminates premutagenic lesions that arise via DNA biosynthetic errors; components of the repair system ...
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53
DNA mismatch repair protein MutH - Escherichia coli ... - UniProt
https://www.uniprot.org/uniprot/B7MLH7
Recommended name. DNA mismatch repair protein MutH UniRule annotation · Alternative names. Methyl-directed mismatch repair protein UniRule annotation ...
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https://www.uniprot.org/uniprot/B7MLH7
Recommended name. DNA mismatch repair protein MutH UniRule annotation · Alternative names. Methyl-directed mismatch repair protein UniRule annotation ...
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54
DNA mismatch repair protein MutH (IPR004230) - InterPro entry
https://www.ebi.ac.uk/interpro/entry/IPR004230
MutS, MutL and MutH are the three essential proteins for initiation of methyl-directed DNA mismatch repair to correct mistakes made during DNA replication ...
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https://www.ebi.ac.uk/interpro/entry/IPR004230
MutS, MutL and MutH are the three essential proteins for initiation of methyl-directed DNA mismatch repair to correct mistakes made during DNA replication ...
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55
Spectrum of DNA mismatch repair failures viewed through the ...
https://portlandpress.com/clinsci/article/136/5/383/230998/Spectrum-of-DNA-mismatch-repair-failures-viewed
DNA mismatch repair (MMR) is a highly conserved system with a major role in maintaining genomic stability. A proficient MMR mechanism greatly ...
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https://portlandpress.com/clinsci/article/136/5/383/230998/Spectrum-of-DNA-mismatch-repair-failures-viewed
DNA mismatch repair (MMR) is a highly conserved system with a major role in maintaining genomic stability. A proficient MMR mechanism greatly ...
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56
Diagnosis of Constitutional Mismatch Repair-Deficiency ...
https://www.gastrojournal.org/article/S0016-5085(15)00872-0/abstract
by S Bodo · 2015 · Cited by 78 —
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https://www.gastrojournal.org/article/S0016-5085(15)00872-0/abstract
by S Bodo · 2015 · Cited by 78 —
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57
The mismatch repair and base excision repair pathways
https://www.tandfonline.com/doi/pdf/10.4161/cbt.8.12.8750
maintenance include mismatch repair (MMR) and base excision repair (BER). ... lated by its amino terminal methyl binding domain while acting.
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https://www.tandfonline.com/doi/pdf/10.4161/cbt.8.12.8750
maintenance include mismatch repair (MMR) and base excision repair (BER). ... lated by its amino terminal methyl binding domain while acting.
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58
Crosstalk between mismatch repair and base excision repair ...
https://moh-it.pure.elsevier.com/en/publications/crosstalk-between-mismatch-repair-and-base-excision-repair-in-hum
DNA repair gene expression in a set of gastric cancers suggested an inverse association between the expression of the mismatch repair (MMR) ...
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https://moh-it.pure.elsevier.com/en/publications/crosstalk-between-mismatch-repair-and-base-excision-repair-in-hum
DNA repair gene expression in a set of gastric cancers suggested an inverse association between the expression of the mismatch repair (MMR) ...
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59
Defective DNA mismatch repair in acute myeloid leukemia ...
https://ashpublications.org/blood/article/104/3/822/18464/Defective-DNA-mismatch-repair-in-acute-myeloid
Cellular resistance to thiopurines is associated with DNA mismatch repair (MMR) deficiency. We demonstrate that thiopurine treatment of ...
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https://ashpublications.org/blood/article/104/3/822/18464/Defective-DNA-mismatch-repair-in-acute-myeloid
Cellular resistance to thiopurines is associated with DNA mismatch repair (MMR) deficiency. We demonstrate that thiopurine treatment of ...
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60
The methylation-independent mismatch repair machinery in ...
https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.001120?crawler=true
MMR involves four basic steps; (i) scanning and detection of mismatches on DNA, (ii) discrimination between parental and daughter strands, (iii) ...
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https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.001120?crawler=true
MMR involves four basic steps; (i) scanning and detection of mismatches on DNA, (ii) discrimination between parental and daughter strands, (iii) ...
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61
DNA Repair
http://www.csun.edu/~cmalone/pdf360/Ch15-2repairtanspose.pdf
Since many mutations are deleterious, DNA repair systems ... In bacteria, methyl-directed mismatch repair finds these errors on.
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http://www.csun.edu/~cmalone/pdf360/Ch15-2repairtanspose.pdf
Since many mutations are deleterious, DNA repair systems ... In bacteria, methyl-directed mismatch repair finds these errors on.
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62
Methyl Mismatch Repair - 393 Words | Bartleby
https://www.bartleby.com/essay/Methyl-Mismatch-Repair-FJWQ72NHA3M
Free Essay: 1. Methyl Mismatch Repair (MMR) To repair mismatched bases, the system has to know which base is the correct one. In order to recognize the...
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https://www.bartleby.com/essay/Methyl-Mismatch-Repair-FJWQ72NHA3M
Free Essay: 1. Methyl Mismatch Repair (MMR) To repair mismatched bases, the system has to know which base is the correct one. In order to recognize the...
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63
Mismatch repair-dependent metabolism of O6 ... - Xenbase
https://www.xenbase.org/entry/literature/article.do?method=display&articleId=50298
The cytotoxicity of SN1-type alkylating agents such as N-methyl-N''-nitrosourea (MNU), N-methyl-N''-nitro-N-nitrosoguanidine (MNNG), or the ...
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https://www.xenbase.org/entry/literature/article.do?method=display&articleId=50298
The cytotoxicity of SN1-type alkylating agents such as N-methyl-N''-nitrosourea (MNU), N-methyl-N''-nitro-N-nitrosoguanidine (MNNG), or the ...
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64
SOLVED: Question 11 During methyl-directed mismatch repair ...
https://www.numerade.com/ask/question/question-11-during-methyl-directed-mismatch-repair-how-does-the-repair-machinery-know-which-dna-strand-is-incorrect-group-of-answer-choices-incorrectly-added-bases-are-methylated-so-that-the-04578/
The mismatch repair machinery recognizes the unmethylated status of the newly-synthesized strand. The mismatch only distorts the shape of the ...
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https://www.numerade.com/ask/question/question-11-during-methyl-directed-mismatch-repair-how-does-the-repair-machinery-know-which-dna-strand-is-incorrect-group-of-answer-choices-incorrectly-added-bases-are-methylated-so-that-the-04578/
The mismatch repair machinery recognizes the unmethylated status of the newly-synthesized strand. The mismatch only distorts the shape of the ...
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65
DNA mismatch repair - Medical Dictionary
https://medical-dictionary.thefreedictionary.com/DNA+mismatch+repair
A METHYL TRANSFERASE ENZYME acts slowly after DNA REPLICATION to ensure that the daughter strand remains undermethylated, relative to the parent strand, for a ...
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https://medical-dictionary.thefreedictionary.com/DNA+mismatch+repair
A METHYL TRANSFERASE ENZYME acts slowly after DNA REPLICATION to ensure that the daughter strand remains undermethylated, relative to the parent strand, for a ...
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66
KEGG PATHWAY: hsa03430
https://www.genome.jp/entry/hsa03430
DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches ...
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https://www.genome.jp/entry/hsa03430
DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches ...
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67
Gynecological Cancers Caused by Deficient Mismatch Repair ...
https://www.mdpi.com/2072-6694/12/11/3319/htm
MSI is linked to mutations in mismatch repair (MMR) genes that cause mismatch repair deficit (dMMR) in human cells. Discovery of new therapeutic approaches ...
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https://www.mdpi.com/2072-6694/12/11/3319/htm
MSI is linked to mutations in mismatch repair (MMR) genes that cause mismatch repair deficit (dMMR) in human cells. Discovery of new therapeutic approaches ...
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68
DNA mismatch repair - Wikiwand
https://www.wikiwand.com/en/DNA_mismatch_repair
DNA mismatch repair (MMR) is a system for recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA ...
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https://www.wikiwand.com/en/DNA_mismatch_repair
DNA mismatch repair (MMR) is a system for recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA ...
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69
Recognition of DNA alterations by the mismatch repair system.
https://www.semanticscholar.org/paper/Recognition-of-DNA-alterations-by-the-mismatch-Marra-Sch%C3%A4r/8accea523b84f1c731eb091f7e7a694fc95fd782/figure/1
Figure 2 Model for the methyl-directed DNA mismatch repair pathway in E. coli - "Recognition of DNA alterations by the mismatch repair ...
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https://www.semanticscholar.org/paper/Recognition-of-DNA-alterations-by-the-mismatch-Marra-Sch%C3%A4r/8accea523b84f1c731eb091f7e7a694fc95fd782/figure/1
Figure 2 Model for the methyl-directed DNA mismatch repair pathway in E. coli - "Recognition of DNA alterations by the mismatch repair ...
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70
DNA Mismatch Repair - Brain Tumors - GUWS Medical
https://www.guwsmedical.info/brain-tumors/dna-mismatch-repair.html
MMR functions in resistance to alkylating agent chemotherapy when the O6-methylguanine adduct is not repaired by MGMT prior to DNA ...
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https://www.guwsmedical.info/brain-tumors/dna-mismatch-repair.html
MMR functions in resistance to alkylating agent chemotherapy when the O6-methylguanine adduct is not repaired by MGMT prior to DNA ...
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71
14.15 Controlling the direction of mismatch repair - GENES IV
http://genes.atspace.org/14.15.html
For example, for cases such as the deamination of 5-methyl-cytosine to thymine, there is a special system to restore the proper sequence. The deamination ...
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http://genes.atspace.org/14.15.html
For example, for cases such as the deamination of 5-methyl-cytosine to thymine, there is a special system to restore the proper sequence. The deamination ...
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72
Biology:DNA mismatch repair - HandWiki
https://handwiki.org/wiki/Biology:DNA_mismatch_repair
DNA mismatch repair (MMR) is a system for recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA ...
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https://handwiki.org/wiki/Biology:DNA_mismatch_repair
DNA mismatch repair (MMR) is a system for recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA ...
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73
DNA Repair - Biochemistry - Medbullets Step 1
https://step1.medbullets.com/biochemistry/102012/dna-repair
Mismatch Repair. Process. repairs G/T or A/C pairing. sometimes misincorporated due to tautomerization of the nucleotide.
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https://step1.medbullets.com/biochemistry/102012/dna-repair
Mismatch Repair. Process. repairs G/T or A/C pairing. sometimes misincorporated due to tautomerization of the nucleotide.
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74
Review - CORE
https://core.ac.uk/download/pdf/82118320.pdf
relations between tissue-specific expression and methyl- ation of non-CpG islands, including, ... such as mismatch repair deficiency states, are not all.
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https://core.ac.uk/download/pdf/82118320.pdf
relations between tissue-specific expression and methyl- ation of non-CpG islands, including, ... such as mismatch repair deficiency states, are not all.
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75
What is methyl directed mismatch repair? - Shakuhachi.net
https://www.shakuhachi.net/what-is-methyl-directed-mismatch-repair/
In Escherichia coli, the methyl-directed mismatch repair (MMR) system is initiated after replication and one of its primary functions is to ...
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https://www.shakuhachi.net/what-is-methyl-directed-mismatch-repair/
In Escherichia coli, the methyl-directed mismatch repair (MMR) system is initiated after replication and one of its primary functions is to ...
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76
The Recombination of Genetic Material - Page 97 - Google Books Result
https://books.google.com/books?id=lWPwcwKwFY0C&pg=PA97&lpg=PA97&dq=methyl+mismatch+repair&source=bl&ots=hgDpkQEqtt&sig=ACfU3U2mnRWUWPSHTkHu6ZpruTRMbapBEw&hl=en&sa=X&ved=2ahUKEwjzirm86cv7AhWtKFkFHSVIDE8Q6AF6BQiaAhAD
Methyl-Directed Mismatch Repair Although mismatch repair clearly is involved in a number of phenomena of genetic recombination, this does not tell us why ...
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https://books.google.com/books?id=lWPwcwKwFY0C&pg=PA97&lpg=PA97&dq=methyl+mismatch+repair&source=bl&ots=hgDpkQEqtt&sig=ACfU3U2mnRWUWPSHTkHu6ZpruTRMbapBEw&hl=en&sa=X&ved=2ahUKEwjzirm86cv7AhWtKFkFHSVIDE8Q6AF6BQiaAhAD
Methyl-Directed Mismatch Repair Although mismatch repair clearly is involved in a number of phenomena of genetic recombination, this does not tell us why ...
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77
DNA Methylation: Biochemistry and Biological Significance
https://books.google.com/books?id=c6zeBwAAQBAJ&pg=PA93&lpg=PA93&dq=methyl+mismatch+repair&source=bl&ots=lBqWkYBPWh&sig=ACfU3U0Lt3bf8mZnPyf5m_e0nC43Eaccxg&hl=en&sa=X&ved=2ahUKEwjzirm86cv7AhWtKFkFHSVIDE8Q6AF6BQiZAhAD
It is possible that methyl-directed repair is restricted to the Enterobacteria. A more general model for mismatch repair envisions single-strand breaks in ...
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https://books.google.com/books?id=c6zeBwAAQBAJ&pg=PA93&lpg=PA93&dq=methyl+mismatch+repair&source=bl&ots=lBqWkYBPWh&sig=ACfU3U0Lt3bf8mZnPyf5m_e0nC43Eaccxg&hl=en&sa=X&ved=2ahUKEwjzirm86cv7AhWtKFkFHSVIDE8Q6AF6BQiZAhAD
It is possible that methyl-directed repair is restricted to the Enterobacteria. A more general model for mismatch repair envisions single-strand breaks in ...
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78
DNA Repair in Cancer Therapy: Molecular Targets and Clinical ...
https://books.google.com/books?id=QQYrIYMNGwIC&pg=PA207&lpg=PA207&dq=methyl+mismatch+repair&source=bl&ots=uRq7tOmwya&sig=ACfU3U0BM3JyLL_ZGX4wj8Vv11Tid8hoOg&hl=en&sa=X&ved=2ahUKEwjzirm86cv7AhWtKFkFHSVIDE8Q6AF6BQibAhAD
Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2. Mol Biol Cell 2005;16:1513e26. Adamson AW, Kim WJ, Shangary S, ...
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https://books.google.com/books?id=QQYrIYMNGwIC&pg=PA207&lpg=PA207&dq=methyl+mismatch+repair&source=bl&ots=uRq7tOmwya&sig=ACfU3U0BM3JyLL_ZGX4wj8Vv11Tid8hoOg&hl=en&sa=X&ved=2ahUKEwjzirm86cv7AhWtKFkFHSVIDE8Q6AF6BQibAhAD
Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2. Mol Biol Cell 2005;16:1513e26. Adamson AW, Kim WJ, Shangary S, ...
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79
Candida and Candidiasis - Google Books Result
https://books.google.com/books?id=9u6rBAAAQBAJ&pg=PT146&lpg=PT146&dq=methyl+mismatch+repair&source=bl&ots=g-ImBOtiOI&sig=ACfU3U1VcQQ5ei7fFOmvQq_uwdevaH6Y8w&hl=en&sa=X&ved=2ahUKEwjzirm86cv7AhWtKFkFHSVIDE8Q6AF6BQiYAhAD
... from errors during normal DNA replication by polymerases δ and ε (80) and are usually corrected before being fixed by methyl mismatch repair (MMR).
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https://books.google.com/books?id=9u6rBAAAQBAJ&pg=PT146&lpg=PT146&dq=methyl+mismatch+repair&source=bl&ots=g-ImBOtiOI&sig=ACfU3U1VcQQ5ei7fFOmvQq_uwdevaH6Y8w&hl=en&sa=X&ved=2ahUKEwjzirm86cv7AhWtKFkFHSVIDE8Q6AF6BQiYAhAD
... from errors during normal DNA replication by polymerases δ and ε (80) and are usually corrected before being fixed by methyl mismatch repair (MMR).
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80
Fenbendazole for liver cancer
https://zakward.me/fenbendazole-for-liver-cancer.html
... [5-(phenylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester, is widely used to ... (MSI-H) or mismatch repair deficient (dMMR) colorectal cancer.
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https://zakward.me/fenbendazole-for-liver-cancer.html
... [5-(phenylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester, is widely used to ... (MSI-H) or mismatch repair deficient (dMMR) colorectal cancer.
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81
DNA damage and repair - Osmosis
https://www.osmosis.org/learn/DNA_damage_and_repair
Next is mismatch repair - which relies on special proteins, called MSH proteins - and fixes the remaining errors after replication. When MSH ...
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https://www.osmosis.org/learn/DNA_damage_and_repair
Next is mismatch repair - which relies on special proteins, called MSH proteins - and fixes the remaining errors after replication. When MSH ...
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