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1 Tumour heterogeneity and evolutionary dynamics in colorectal ...
https://www.nature.com/articles/s41389-021-00342-x
While most studies have focused on the genetic heterogeneity of CRC, another source of heterogeneity may arise from the transcriptional profile ...
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2 Tumor Heterogeneity in Colorectal Cancer: What Do We Know ...
https://www.karger.com/Article/FullText/486721
Intertumor heterogeneity comprises differences in tumors of the same histologic type between patients, and, more rarely, differences in ...
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3 Intratumor CMS Heterogeneity Impacts Patient Prognosis in ...
https://aacrjournals.org/clincancerres/article/27/17/4768/671638/Intratumor-CMS-Heterogeneity-Impacts-Patient
The consensus molecular subtypes (CMS) represent a significant advance in the understanding of intertumor heterogeneity in colon cancer.
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4 The heterogeneous clinical and pathological landscapes of ...
https://cancerci.biomedcentral.com/articles/10.1186/s12935-020-1117-2
Colorectal cancer (CRC) is a complex and molecularly heterogeneous disease representing one of the most frequent causes of cancer-related ...
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5 Heterogeneity of colon cancer: from bench to bedside
https://www.esmoopen.com/article/S2059-7029(20)32424-8/fulltext
The large bowel shows biomolecular, anatomical and bacterial changes that proceed from the proximal to the distal tract. These changes account for the ...
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6 Colon Cancer Heterogeneity: Welcome to the RiboZone
https://www.cell.com/cell-stem-cell/pdf/S1934-5909(20)30203-4.pdf
Intratumoral heterogeneity is one of the key hallmarks of colorectal cancer (CRC) and it is apparent that most tumors harbor cells with various ...
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7 Intratumor heterogeneity: A new perspective on colorectal ...
https://onlinelibrary.wiley.com/doi/full/10.1002/cam4.3323
Over time, researchers have discovered that colorectal cancers are not homogeneous, but rather heterogeneous, consisting of many different ...
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8 Transcriptomic and proteomic intra-tumor heterogeneity of ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0241148
Intra-tumor heterogeneity (ITH) of colorectal cancer (CRC) complicates molecular tumor classification, such as transcriptional subtyping.
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9 Implications of Intratumor Heterogeneity on Consensus ... - MDPI
https://www.mdpi.com/2072-6694/13/19/4923
Colorectal cancer (CRC) has been divided into four consensus molecular subtypes (CMS) using the unsupervised clustering of bulk transcriptomic data. The CMS, ...
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10 Tumor evolution and intratumor heterogeneity in colorectal ...
https://jgo.amegroups.com/article/view/4860/html
A higher level of intratumor heterogeneity is seen in genes that are not as frequently mutated in CRC. Many of these events do not appear to be functional in ...
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11 The clonal evolution of metastatic colorectal cancer - Science
https://www.science.org/doi/10.1126/sciadv.aay9691
Tumor heterogeneity and evolution drive treatment resistance in metastatic colorectal cancer (mCRC). Patient-derived xenografts (PDXs) can model mCRC ...
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12 Genomic temporal heterogeneity of circulating tumour DNA in ...
https://gut.bmj.com/content/71/7/1340
Objective Circulating tumour DNA (ctDNA) sequencing is increasingly used in the clinical management of patients with colorectal cancer. However, the genomic ...
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13 Heterogeneity of KRAS, NRAS, BRAF and PIK3CA mutations ...
https://www.annalsofoncology.org/article/S0923-7534(19)31838-1/fulltext
Evidence suggests that metastatic colorectal carcinoma (mCRC) has a high level of intratumor heterogeneity. We carried out a quantitative assessment of tumor ...
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14 Intra-tumor heterogeneity of colorectal cancer | CMAR
https://www.dovepress.com/intra-tumor-heterogeneity-of-colorectal-cancer-necessitates-the-multi--peer-reviewed-fulltext-article-CMAR
› intra-tumor-heterogeneity...
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15 Tumor Heterogeneity as a Predictor of Response to ...
https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1045&context=pathology_facpub
We analyzed 21 pretreatment rectal cancer biopsy samples and found a positive correlation of the response to therapy with a quantitative mutant-allele tumor ...
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16 Evolution of intratumoral genetic heterogeneity during ...
https://academic.oup.com/carcin/article/26/5/916/2390861
In primary colorectal cancers (CRCs), intratumoral genetic heterogeneity was more often observed in early than in advanced stages, at 90 and 67%, respectively.
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17 Definition of tumor heterogeneity - NCI Dictionary of Cancer ...
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/tumor-heterogeneity
A term that describes the differences between tumors of the same type in different patients, the differences between cancer cells within a single tumor, or the ...
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18 ICGC-ARGO precision medicine: targeted therapy according ...
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(22)00142-5/fulltext
Colorectal cancer is characterised by high molecular heterogeneity and genomic alterations in common cancer drivers, including RAS, BRAF, ...
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19 Heterogeneity in Microsatellite Instability in Metastatic ...
https://jnccn.org/view/journals/jnccn/17/10/article-p1263.xml
Targeted therapy has exposed a high degree of tumor heterogeneity in colorectal cancer (CRC). Compared with other cancer types, ...
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20 The molecular characteristics of colorectal cancer
https://www.spandidos-publications.com/10.3892/ol.2018.8679
A growing body of scientific evidences suggests that CRC is a heterogeneous disease, and genetic characteristics of the tumors determine ...
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21 Spatio-temporal tumor heterogeneity in metastatic CRC tumors
https://www.oncotarget.com/article/26081/text/
Overall, our results show that colorectal cancers are highly heterogeneous tumors at the intratumoral and intertumoral genetic levels, which ...
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22 Intratumoral Genetic Heterogeneity in Rectal Cancer
https://journals.lww.com/annalsofsurgery/Fulltext/2017/01000/Intratumoral_Genetic_Heterogeneity_in_Rectal.39.aspx
Considerable intratumoral heterogeneity is present among naive rectal cancers. The majority of point mutations detected in different fragments from rectal ...
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23 Colorectal Cancer Heterogeneity and the Impact on Precision ...
https://mdpi-res.com/d_attachment/biomedicines/biomedicines-10-01035/article_deploy/biomedicines-10-01035-v2.pdf?version=1651741483
Abstract: Novel targeted therapies for metastatic colorectal cancer are needed to personalize treat- ments by guiding specific biomarkers ...
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24 Precision Medicine of Colorectal Cancer Heterogeneity
https://encyclopedia.pub/entry/22850
Colorectal cancer (CRC) is a major global health issue, being the third most commonly diagnosed malignancy with an estimated number of more ...
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25 RAS heterogeneity as a prognostic marker in metastatic ...
https://ascopubs.org/doi/abs/10.1200/JCO.2017.35.4_suppl.586
Background: The impact of intratumor heterogeneity on prognosis in metastatic colorectal cancer (mCRC) is unclear, however relative variant ...
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26 Molecular Heterogeneity in Colorectal Cancer: Insights from ...
https://www.researchgate.net/publication/354619775_Molecular_Heterogeneity_in_Colorectal_Cancer_Insights_from_Genetic_Profiling
The high heterogeneity has become apparent in metastatic colorectal cancer (CRC) and the solitary leading causes of cancer mortality ...
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27 Colon Cancer Heterogeneity: Welcome to the RiboZone.
https://europepmc.org/article/med/32502398
(2020) shed new light on the hierarchical organization of cells within colorectal cancer. They show that tumor cells at the apex of this hierarchy reside in ...
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28 The biological complexity of colorectal cancer - SAGE Journals
https://journals.sagepub.com/doi/10.1177/1756283X16659790
Colorectal cancers are characterized by great genotypic and phenotypic heterogeneity, including tumor microenvironment and interactions between healthy and ...
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29 Heterogeneity of mismatch repair defect in colorectal cancer ...
https://www.ejcancer.com/article/S0959-8049(18)30121-7/fulltext
Microsatellite instability is considered as an early event in carcinogenesis of colorectal deficient DNA mismatch repair system without tumoural ...
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30 Heterogeneity of Colorectal Cancer Progression
https://pdfs.semanticscholar.org/161b/40644c0a32fa43f8594b5864c479ea021e25.pdf
Keywords: colorectal cancer; progression; heterogeneity. 1. Heterogeneous Gene Damage and Different Progression of Colorectal Cancer.
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31 Heterogeneity of Colorectal Cancer Risk Factors by ...
https://www.cghjournal.org/article/S1542-3565(18)30756-0/fulltext
Current smoking was associated with a greater risk of rectal and proximal colon cancer, but not distal colon cancer (P heterogeneity = .05). No ...
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32 Contrast-enhanced CT Texture as a Biomarker of 5-year ...
https://pubs.rsna.org/doi/full/10.1148/radiol.12120254?prevSearch=&searchHistoryKey=
Assessment of Primary Colorectal Cancer Heterogeneity by Using Whole-Tumor Texture Analysis: Contrast-enhanced CT Texture as a Biomarker of ...
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33 Intratumor CMS Heterogeneity Impacts Patient ... - Institut Curie
https://institut-curie.org/publications/intratumor-cms-heterogeneity-impacts-patient-prognosis-localized-colon-cancer
Results: Over 55% of tumors corresponded to mixtures of at least two CMSs, demonstrating pervasive ITH in colon cancer. Of note, ITH was ...
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34 'Big Bang' Model of Cancer Heterogeneity | ESMO
https://www.esmo.org/oncology-news/archive/big-bang-model-of-cancer-heterogeneity
A new study shows that colorectal cancers acquire their dominant mutations early in development and that subsequent mutations, ...
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35 Intratumor Heterogeneity and Evolution of Colorectal Cancer
https://www.biorxiv.org/content/10.1101/2020.01.13.904276v2
Intratumor heterogeneity (ITH) enable us to understand the evolution of cancer. ITH and evolution of colorectal cancer (CRC) has not been well ...
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36 Genetic Heterogeneity in Colorectal Cancer Associations ...
https://www.gastrojournal.org/article/S0016-5085(10)01101-7/fulltext
Genome-wide association studies of colorectal cancer (CRC) have identified risk variants in 10 genomic regions.
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37 Heterogeneity in quality of life of long-term colon cancer ...
https://research.tilburguniversity.edu/en/publications/heterogeneity-in-quality-of-life-of-long-term-colon-cancer-surviv
Implications for Practice: Long-term colon cancer survivors show great heterogeneity in their health-related quality of life. This study identified five ...
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38 Itraconazole targets cell cycle heterogeneity in colorectal cancer
https://rupress.org/jem/article/215/7/1891/42339/Itraconazole-targets-cell-cycle-heterogeneity-in
CRC is a heterogeneous disease and recent large scale molecular studies have identified clinically relevant overlapping subgroups that can be ...
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39 Heterogeneity of Colorectal Cancer Risk Factors by ...
https://einstein.pure.elsevier.com/en/publications/heterogeneity-of-colorectal-cancer-risk-factors-by-anatomical-sub
Current smoking was associated with a greater risk of rectal and proximal colon cancer, but not distal colon cancer (P heterogeneity = .05). No heterogeneity by ...
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40 Intra-tumor Heterogeneity in Colorectal Cancer Progression ...
https://grantome.com/grant/NIH/K08-CA190645-04
We and others have identified genetic sub-clones in CRC. In other tumor types, recent studies have highlighted the potential role of genetic heterogeneity in ...
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41 Characterization of molecular heterogeneity of colorectal ...
https://www.medrxiv.org/content/10.1101/2022.11.15.22282336v1
Methods The mutational characteristics of 24 colorectal tumor samples from Bangladeshi patients were investigated using targeted next generation ...
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42 Research findings about genomic heterogeneity in colon ...
https://stsiweb.org/index.php/translational_research/research_highlights/cancer/human_tumor_sequencing/resarch_findings_about_genomic_heterogeneity_in_colon_cancer_presented_at_a/
In different anatomic areas of one patient's colon cancer, Dr Levy and his collaborators at The Scripps Research Institute (TSRI) and Scripps Clinic used a ...
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43 Tumor heterogeneity in colon cancer: therapeutic implications
https://www.cnr.it/en/event/15113/tumor-heterogeneity-in-colon-cancer-therapeutic-implications
By using next generation sequencing (NGS)-based techniques, we have described the molecular heterogeneity of CRC within a clinical trial aiming ...
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44 Heterogeneity of colon cancer: from bench to bedside
https://soundcloud.com/bmjpodcasts/esmo-podcast-heterogeneity-of-colorectal-cancer
Play Heterogeneity of colon cancer: from bench to bedside by BMJ talk medicine on desktop and mobile. Play over 265 million tracks for free ...
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45 Genetic and biological hallmarks of colorectal cancer
http://genesdev.cshlp.org/content/35/11-12/787.full
In summary, CRC genome instability mechanisms, presenting as CIN or MSI, contribute to tumor heterogeneity but with distinct genetic and biological features ...
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46 BRAF V600E mutations in right-side colon cancer
https://www.ejso.com/article/S0748-7983(22)00042-7/fulltext
In addition, spatial heterogeneity of BRAFV600E mutations also exists, as for RAS mutations. In this prospective observational study, we ...
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47 Genetic and Epigenetic Intra-tumour Heterogeneity in ...
https://d-nb.info/1125422297/34
Abstract. Introduction Colorectal cancer (CRC) is a highly heterogeneous disease, with pathologically similar cancers having.
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48 Uncovering tumour heterogeneity through PKR and nc886 ...
https://digitalcommons.wustl.edu/cgi/viewcontent.cgi?article=9803&context=open_access_pubs
Uncovering tumour heterogeneity through PKR and nc886 analysis in metastatic colon cancer patients treated with 5-FU- based chemotherapy.
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49 Colorectal Cancer (CRC) Cellular Heterogeneity, Metastasis ...
https://vivo.weill.cornell.edu/display/grant-0000052909
VIVOWeill Cornell Medical College · Colorectal Cancer (CRC) Cellular Heterogeneity, Metastasis, and a Spatially-resolved Molecular Atlas for ...
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50 Clonal dynamics and tumor cell heterogeneity in colorectal ...
https://edoc.ub.uni-muenchen.de/22224/
Colon cancers are composed of phenotypically heterogeneous tumor cell subpopulations with variable expression of putative stem cell and ...
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51 Heterogeneity and Cancer
https://www.cancernetwork.com/view/heterogeneity-and-cancer
Cancer heterogeneity, long recognized as an important clinical determinant of patient outcomes, was poorly understood at a molecular level.
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52 Full article: Inter-tumor heterogeneity - Taylor & Francis Online
https://www.tandfonline.com/doi/full/10.4161/hv.21203
At this time we expose the totality of the KRAS wild type population to EGFR inhibitors, which compromises 60% of all colon cancer despite knowing that only 30% ...
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53 Tumor Heterogeneity Could Impact Treatment of Colorectal ...
https://www.genomeweb.com/sequencing-technology/tumor-heterogeneity-could-impact-treatment-colorectal-cancer-patients
For synchronous colorectal cancer, heterogeneity also means that taking a biopsy from just one primary tumor will not suffice as a way to ...
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54 Tumour heterogeneity - Wikipedia
https://en.wikipedia.org/wiki/Tumour_heterogeneity
Tumour heterogeneity describes the observation that different tumour cells can show distinct morphological and phenotypic profiles, including cellular ...
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55 Cancer heterogeneity—a multifaceted view | EMBO reports
https://www.embopress.org/doi/10.1038/embor.2013.92
This so-called intra-tumour heterogeneity poses an important challenge for predicting tumour behaviour and clinical outcome. Differences exist ...
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56 Microniches of intratumoral microbiota impact spatial and ...
https://www.news-medical.net/news/20221122/Microniches-of-intratumoral-microbiota-impact-spatial-and-cellular-heterogeneity-in-cancer.aspx
... microbiota impact spatial and cellular heterogeneity in cancer ... oral squamous cell carcinoma (OSCC) and colorectal cancer (CRC).
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57 Tumour Cell Heterogeneity - F1000Research
https://f1000research.com/articles/5-238
The population of cells that make up a cancer are manifestly heterogeneous at the genetic, epigenetic, and phenotypic levels.
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58 How bacteria could help tumors progress and resist treatment
https://www.sciencedaily.com/releases/2022/11/221116113125.htm
In the lab, the researchers grew colorectal cancer spheroids, which are tumor cells grown in 3D clusters, with immune cells called neutrophils, ...
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59 Pathophysiology and Characterization of Colorectal Cancers
https://www.youtube.com/watch?v=RG6gQL3YvWE
AIG Hospitals
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60 Tumour heterogeneity and the impact on patient care - ecancer
https://ecancer.org/en/video/5137-tumour-heterogeneity-and-the-impact-on-patient-care
› video › 5137-tumour-heterogeneity-...
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61 Colon Cancer Treatment | Johns Hopkins Medicine
https://www.hopkinsmedicine.org/health/conditions-and-diseases/colon-cancer/colon-cancer-treatment
When colon cancer metastasizes (spreads), it usually appears in the liver. It may also spread to the lungs, brain, peritoneum (the lining of the abdominal ...
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62 The Immune Landscape of Cancer - Spiral
https://spiral.imperial.ac.uk/bitstream/10044/1/71213/5/1-s2.0-S1074761318301213-main.pdf
heterogeneous tumors and the resulting data are intended to serve as a resource for future ... [colon adenocarcinoma], READ [rectum adenocarcinoma]) and.
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63 RHR: The Truth About Red Meat - Chris Kresser
https://chriskresser.com/review-on-the-truth-about-red-meat/
The ROS for colorectal cancer was 0.057. ... heterogeneity, an inability to disentangle effects from other dietary and lifestyle factors, ...
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64 搜索
https://www.x-mol.com/paper/1310999416361160704
... environmental factors has made colorectal cancer (CRC), which involves the colon and rectum, a challenging and heterogeneous cancer.
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65 Hereditary Colorectal Cancer | ASCRS
https://fascrs.org/patients/diseases-and-conditions/a-z/hereditary-colorectal-cancer
All cancers, but especially colon and rectal cancers, commonly referred to as colorectal cancer (CRC), have hereditary factors that potentially increase ...
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66 Irritable bowel syndrome: Psychological stress linked to IBS ...
https://www.medicalnewstoday.com/articles/irritable-bowel-syndrome-study-finds-link-between-ibs-symptoms-and-stress
Irritable bowel syndrome: Study finds link between IBS symptoms and ... “The extreme heterogeneity of IBS, however, makes it so that the ...
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67 Pain in Lower Right Abdomen: 16 Possible Causes - Healthline
https://www.healthline.com/health/pain-in-lower-right-abdomen
loss of appetite; nausea or vomiting; abdominal swelling; fever; bowel ... that cause changes in bowel tissue and increase your risk of colorectal cancer.
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68 Pathology+week+5 - week 4 and 5 lecture notes for midterm
https://www.studocu.com/en-ca/document/the-university-of-western-ontario/human-pathology/pathologyweek5-week-4-and-5-lecture-notes-for-midterm/40140181
Tumour Progression & Heterogeneity ... P53 → lung, colon, breast, ovary & other cancers. ... MSH2, MLH2 in hereditary non-polyposis colon cancer.
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69 Does thinking make it so? The placebo myth rears its ugly ...
https://scienceblogs.com/insolence/2016/12/20/does-thinking-make-it-so-the-placebo-myth-rears-its-ugly-head-again
In our research group's experiments, patients with illnesses such as irritable bowel syndrome, chronic low back pain, and episodic migraine ...
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70 Herringbone artifact | Radiology Reference Article
https://radiopaedia.org/articles/herringbone-artifact
apple core sign (colon) · apple core sign (femur) ... radiation-induced lung cancer ... tissue heterogeneity and foreign bodies.
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71 Metastatic Colon Cancer - Buffalo, NY
https://www.roswellpark.org/cancer/colorectal/metastatic-colon-cancer
When colorectal cancer spreads to a distant site in the body, it is called metastatic disease. These tumors or lesions in the new site — most commonly the ...
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72 Erik P. Sulman, MD, PhD - Harnessing Novel Synergies With ...
https://player.fm/series/peerview-gastroenterology-cmecnecpe-audio-podcast/erik-p-sulman-md-phd-harnessing-novel-synergies-with-tumor-treating-fields-insights-on-improving-survival-with-multimodal-care-in-aggressive-tumors
Erik P. Sulman, MD, PhD - Harnessing Novel Synergies With Tumor Treating ... Thyroid, Colon, Breast, and Other Solid Tumors to Enable All ...
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73 Most metastatic colorectal cancers have spread before ...
https://med.stanford.edu/news/all-news/2019/06/most-metastatic-colorectal-cancers-have-spread-before-diagnosis.html
Colorectal cancers often spread before the initial tumor is detected, according to a new Stanford study. Identifying patients in whom early ...
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74 Colon Cancer Treatment
https://www.cancer.northwestern.edu/types-of-cancer/gastrointestinal/colon-cancer.html
Stage II colon cancer. In stage IIA, cancer has spread through the muscle layer of the colon wall to the serosa. In stage IIB, cancer has spread ...
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75 Colon Cancer: New Insights for the Healthcare Professional: ...
https://books.google.com/books?id=Xr9HbNCWh5QC&pg=PA95&lpg=PA95&dq=colon+cancer+heterogeneity&source=bl&ots=bbNwApHS76&sig=ACfU3U3FE5tWkcCgKyPQtX268LHOMw1N8g&hl=en&sa=X&ved=2ahUKEwi2ravx7sz7AhU5r5UCHauCD3AQ6AF6BQikAhAD
(2011 MAY 11) Graduate School of Medicine, Osaka: Heterogeneity of colorectal cancers and extraction of discriminator gene signatures for personalized ...
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76 Stem Cells Heterogeneity in Cancer - Page 117 - Google Books Result
https://books.google.com/books?id=-3iaDwAAQBAJ&pg=PA117&lpg=PA117&dq=colon+cancer+heterogeneity&source=bl&ots=aGtUiWzSoh&sig=ACfU3U3qpv8IlV1EiwSjsaPZD_i7tooIwg&hl=en&sa=X&ved=2ahUKEwi2ravx7sz7AhU5r5UCHauCD3AQ6AF6BQilAhAD
7.1 Heterogeneity within cancer stem cell (CSC) populations and intra- and ... thereby making CSC populations heterogeneous Human colorectal CSCs were first ...
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77 Metastatic Progression and Tumour Heterogeneity
https://books.google.com/books?id=nW0WEAAAQBAJ&pg=PA32&lpg=PA32&dq=colon+cancer+heterogeneity&source=bl&ots=ZG7fDzV4dv&sig=ACfU3U2mxDRjptIZMsdIHvnUqbVMAVVTkw&hl=en&sa=X&ved=2ahUKEwi2ravx7sz7AhU5r5UCHauCD3AQ6AF6BQifAhAD
Accordingly, aggregated colon cancer cells also showed increased metastatic efficiency in the liver when compared with single cells after intra-portal ...
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78 Journal of the National Cancer Institute: JNCI.
https://books.google.com/books?id=vrz__55gEFwC&pg=PA1472&lpg=PA1472&dq=colon+cancer+heterogeneity&source=bl&ots=IhothiShof&sig=ACfU3U1VlchCsRoEDn-eEA9u58ZMosh-kA&hl=en&sa=X&ved=2ahUKEwi2ravx7sz7AhU5r5UCHauCD3AQ6AF6BQigAhAD
consumed or differences in the prevalence of colon cancer risk facCONTEXT AND ... these potential sources of have been less consistent . heterogeneity .
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79 The Heterogeneity of Cancer Metabolism
https://books.google.com/books?id=a5EvEAAAQBAJ&pg=PA146&lpg=PA146&dq=colon+cancer+heterogeneity&source=bl&ots=MHlBGUCSqR&sig=ACfU3U3zKwelbsyuh6ztWrQJqVvsz1vVXA&hl=en&sa=X&ved=2ahUKEwi2ravx7sz7AhU5r5UCHauCD3AQ6AF6BQijAhAD
Adipocytes activate mitochondrial fatty acid oxidation and autophagy to promote tumor growth in colon cancer. Cell Death & Disease, 8(2), e2593. 22.
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80 Medical Image Computing and Computer Assisted Intervention – ...
https://books.google.com/books?id=ibcAEAAAQBAJ&pg=PA295&lpg=PA295&dq=colon+cancer+heterogeneity&source=bl&ots=bUldIf7nG3&sig=ACfU3U2N7xln0EicX-swLC2uHHdiFshRmw&hl=en&sa=X&ved=2ahUKEwi2ravx7sz7AhU5r5UCHauCD3AQ6AF6BQieAhAD
Particularly, genetic mutations play key roles in colon cancer evolution at all ... critical to understand characteristics of cancer heterogeneity [14], ...
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81 Colon Cancer: New Insights for the Healthcare Professional: ...
https://books.google.com/books?id=ta6VE50q8BMC&pg=PA349&lpg=PA349&dq=colon+cancer+heterogeneity&source=bl&ots=7DOMmRDFy4&sig=ACfU3U3lRqYPJr9NKa1W917AlJDJNArDDg&hl=en&sa=X&ved=2ahUKEwi2ravx7sz7AhU5r5UCHauCD3AQ6AF6BQiqAhAD
Nashville: Association. of. genetic. variants. for. colorectal. cancer ... stronger for advanced than non-advanced adenomas (P-heterogeneity 0.038), ...
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82 Advanced Approaches on Multidisciplinary Management of ...
https://books.google.com/books?id=Dy17EAAAQBAJ&pg=PA100&lpg=PA100&dq=colon+cancer+heterogeneity&source=bl&ots=GAFtCLG4Mv&sig=ACfU3U2E8w-JBmHnEw94iPQoEBpF5fbEmA&hl=en&sa=X&ved=2ahUKEwi2ravx7sz7AhU5r5UCHauCD3AQ6AF6BQibAhAD
... there is the possibility of heterogeneity in MSI/dMMR tumors. ... in a subset of CD133+CD24lo colon cancer cells, leading to immune evade (31).
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83 Drug Discovery in Cancer Epigenetics
https://books.google.com/books?id=5hQoCgAAQBAJ&pg=PA138&lpg=PA138&dq=colon+cancer+heterogeneity&source=bl&ots=Y9qBH97fyi&sig=ACfU3U3zALq4CDI--nJJAoAtDN6WghrNSg&hl=en&sa=X&ved=2ahUKEwi2ravx7sz7AhU5r5UCHauCD3AQ6AF6BQidAhAD
Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome ... Navigating the challenge of tumor heterogeneity in cancer therapy.
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84 Colon Cancer - UCSF Colorectal Surgery
https://colorectalsurgery.ucsf.edu/conditions--procedures/colon-cancer.aspx
Colon cancer is a disease in which malignant (cancer) cells form in the tissues of the colon. Health history affects the risk of developing ...
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85 Colorectal Cancer - Learning oncology
https://www.learnoncology.ca/modules/colorectal-cancer
In the past, colon cancer was believed to almost exclusively affect only the left side of the colon. However, the incidence of right-sided colon ...
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