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1 Extended Use of Dabigatran, Warfarin, or Placebo in Venous ...
https://www.nejm.org/doi/full/10.1056/nejmoa1113697
The trial was designed to determine whether 6 months of dabigatran therapy was as effective as 6 months of warfarin therapy (i.e., noninferior) ...
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2 Dabigatran vs. Warfarin in the Extended Treatment of VTE
https://www.acc.org/latest-in-cardiology/clinical-trials/2013/02/20/21/31/remedy
In the current trial, dabigatran 150 mg BID was noninferior to warfarin in reducing recurrent symptomatic VTE or VTE-related deaths compared ...
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3 Extended use of dabigatran, warfarin, or placebo in ... - PubMed
https://pubmed.ncbi.nlm.nih.gov/23425163/
The aims of this clinical trial were to study the appropriateness of a paediatric dabigatran dosing algorithm, and the efficacy and safety of ...
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4 Twice-daily Oral Direct Thrombin Inhibitor Dabigatran ...
https://clinicaltrials.gov/ct2/show/NCT00558259
Any deaths which occured from randomisation to end of post treatment period. All suspected recurrent VTEs and all deaths and bleeding events were evaluated by ...
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5 Treatment of Acute Venous Thromboembolism With ...
https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.113.004450
Dabigatran and warfarin have been compared for the treatment of acute venous thromboembolism (VTE) in a previous trial.
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6 RE-MEDY/RE-SONATE: Dabigatran vs Warfarin in VTE
https://www.medscape.com/viewarticle/779677
That's reminiscent of a much-debated finding in the RE-LY trial that established dabigatran for nonvalvular atrial fibrillation: a 35% (p=0.07) ...
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7 Dabigatran etexilate for the treatment of acute ... - The Lancet
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(20)30368-9/fulltext
The aims of this clinical trial were to study the appropriateness of a paediatric dabigatran dosing algorithm, and the efficacy and safety ...
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8 Safety and Efficacy of Dabigatran Etexilate vs Dose-Adjusted ...
https://jamanetwork.com/journals/jamaneurology/fullarticle/2749167
After the end of treatment or early discontinuation of trial medication, whether a patient received further nontrial treatment was at the ...
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9 RE-COVER - Wiki Journal Club
https://www.wikijournalclub.org/wiki/RE-COVER
The RE-COVER trial is part of an industry-supported series of trials investigating the role of dabigatran as an alternative to warfarin therapy. It was ...
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10 Clinical Trial Study Data | Pradaxa® (dabigatran etexilate)
https://www.pradaxa.com/study-data
In 2010, PRADAXA was the first FDA-approved alternative to warfarin to reduce risk of stroke in atrial fibrillation (AFib) not caused by a heart valve problem.
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11 The RE-COVER trial: Dabigatran non-inferior to warfarin in ...
https://www.2minutemedicine.com/the-re-cover-trial-dabigatran-is-non-inferior-to-warfarin-in-treating-acute-venous-thromboembolism-classics-series/
1. The RE-COVER trial demonstrates that treating acute venous thromboembolism with 6 months of dabigatran 150 mg twice daily is non-inferior to ...
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12 RE-LY study: Randomized Evaluation of Long-term ...
https://academic.oup.com/eurheartj/article/30/21/2554/518562
The RE-LY study8 is a trial of >18 000 patients with atrial fibrillation who were randomized between warfarin or one of two doses of dabigatran etexilate (110 ...
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13 Critical appraisal of dabigatran in the treatment of deep vein ...
https://www.dovepress.com/critical-appraisal-of-dabigatran-in-the-treatment-of-deep-vein-thrombo-peer-reviewed-fulltext-article-JBM
Dabigatran has been proposed as a suitable alternative to warfarin therapy in the treatment of VTE. Therefore, a critical appraisal of ...
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14 Dabigatran for the Treatment and Secondary Prevention of ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0163550
The model was populated with efficacy and safety data from major dabigatran trials (i.e. RE-COVER, RECOVER II, RE-MEDY and RE-SONATE), Dutch ...
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15 (PDF) A Randomized Trial of Dabigatran Versus Warfarin in ...
https://www.researchgate.net/publication/336482624_A_Randomized_Trial_of_Dabigatran_Versus_Warfarin_in_the_Treatment_of_Acute_Venous_Thromboembolism_RE-COVER_II
The frequency of reported ACS events was less than 1% in the trial, with more cases in the dabigatran treatment group than those treated with ...
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16 RE-COVER Study Evaluating Dabigatran Etexilate Met ...
https://www.boehringer-ingelheim.us/press-release/re-cover-study-evaluating-dabigatran-etexilate-met-primary-outcome-six-month-treatment
RE-COVER Study Evaluating Dabigatran Etexilate Met Primary Outcome for the Six-Month Treatment of Patients with Acute Venous Thromboembolism ( ...
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17 Current Status of New Anticoagulants in the Management of ...
https://www.hindawi.com/journals/ah/2012/856341/
(d) RESONATE is a phase III clinical trial that, like REMEDY, evaluates the use of dabigatran as treatment of VTE for an extended period of time.
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18 Treatment options for venous thromboembolism
https://thrombosisjournal.biomedcentral.com/articles/10.1186/s12959-014-0027-8
There is scant real-life evidence data for the direct oral anticoagulants dabigatran, apixaban and edoxaban. A recent retrospective cohort study ...
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19 Temporal trends in initiation of VKA, rivaroxaban, apixaban ...
https://www.nature.com/articles/s41598-017-03596-x
In the RECOVER (Dabigatran versus warfarin in the treatment of acute venous thromboembolism) I and II trials, parenteral heparin was used ...
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20 Venous Thromboembolism Treatment with Dabigatran
https://www.chp.edu/research/clinical-studies/hematology-oncology/rare-cancers-blood-disorders/venous-thromboembolism-treatment-dabigatran
The study begins with a screening visit that includes a physical exam and various medical tests. Participants will be provided either the study drug (dabigatran) ...
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21 Pradaxa, INN-dabigatran etexilate
https://www.ema.europa.eu/en/documents/product-information/pradaxa-epar-product-information_en.pdf
SSRIs and SNRIs increased the risk of bleeding in all treatment groups of a phase III clinical trial comparing dabigatran to warfarin for stroke prevention ...
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22 Dabigatran versus Warfarin in the Treatment of Acute Venous ...
https://www.portailvasculaire.fr/sites/default/files/docs/dabigatran_coumadine_tvp_nejm_2009.pdf
In a randomized, double-blind, noninferiority trial involving patients with acute ve- nous thrombo embolism who were initially given parenteral ...
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23 Venous thromboembolism: Anticoagulation after initial ...
https://www.uptodate.com/contents/venous-thromboembolism-anticoagulation-after-initial-management
Treatment of acute venous thromboembolism with dabigatran or warfarin and ... An analysis of the randomised, double-blind HOKUSAI VTE trial.
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24 Evolving use of new oral anticoagulants for treatment of ...
https://ashpublications.org/blood/article/124/7/1020/33646/Evolving-use-of-new-oral-anticoagulants-for
Although single-dose regimens of rivaroxaban and dabigatran were evaluated in the EINSTEIN-Extension and RE-SONATE trials (20 mg once daily and 150 mg twice ...
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25 PRADAXA® (dabigatran etexilate mesylate) capsules for oral ...
https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/022512s007lbl.pdf
rates in the clinical trials of another drug and may not reflect the ... Treatment of pregnant rats after implantation with dabigatran at the same dose ...
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26 Dabigatran etexilate for the treatment and secondary ... - NICE
https://www.nice.org.uk/guidance/ta327/documents/deep-vein-thrombosis-pulmonary-embolism-dabigatran-etexilate-treatment-prevention-final-appraisal-determination-document2
trials on the effectiveness of dabigatran etexilate for treating deep vein thrombosis (DVT) and pulmonary embolism (PE). The RE-COVER trials.
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27 Guidance for the practical management of the direct oral ...
https://link.springer.com/article/10.1007/s11239-015-1310-7
In the individual DOAC VTE treatment trials [3–10], GI bleeding event rates were too low to draw definite conclusions (dabigatran and ...
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28 Dabigatran (Pradaxa®): A Deep Dive
https://thrombosis.org/2022/07/dabigatran-pradaxa/
When compared with warfarin in some clinical trials, dabigatran ... in treating venous thromboembolism (VTE, which includes DVT and PE).
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29 PRADAXA 75 mg hard capsules - Medsafe
https://www.medsafe.govt.nz/profs/datasheet/p/pradaxacap.pdf
to initiation of treatment with PRADAXA to exclude patients for treatment with severe ... with dabigatran etexilate than with warfarin in the RE-LY study.
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30 Cardiovascular outcomes during treatment with dabigatran
https://search.proquest.com/openview/302d167af7c208d5550825cf663ef0af/1?pq-origsite=gscholar&cbl=3933269
Background: Dabigatran 150 mg twice daily was shown to be superior to warfarin in preventing stroke in subjects with nonvalvular atrial fibrillation (SPAF) in ...
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31 The discovery of dabigatran etexilate for the treatment of ...
https://www.tandfonline.com/doi/abs/10.1080/17460441.2016.1188077
Expert opinion: Dabigatran demonstrated comparable efficacy to the highly effective warfarin, and a more favourable safety profile in trials of VTE treatment. A ...
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32 for the RE-COVER II Trial Investigators* and Clive ... - CORE
https://core.ac.uk/download/pdf/53289971.pdf
Background—Dabigatran and warfarin have been compared for the treatment of acute venous thromboembolism (VTE) in a previous trial. We undertook this study ...
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33 Pradaxa 150 mg hard capsules - (emc)
https://www.medicines.org.uk/emc/product/4703/smpc
Catheter ablation can be conducted in patients on 150 mg twice daily dabigatran etexilate treatment. Dabigatran etexilate treatment does not need to be ...
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34 Effectiveness and safety of reduced dose non-vitamin K ...
https://www.bmj.com/content/356/bmj.j510
Intervention Initiated anticoagulant treatment (dabigatran 110 mg, rivaroxaban 15 mg, apixaban 2.5 mg, and warfarin).
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35 Venothromboembolism: Treatment Recommendations and ...
https://www.pharmacytimes.com/view/venothromboembolism-treatment-recommendations-and-therapeutic-options-
In these trials, dabigatran was compared with warfarin after both treatment groups received initial parenteral anticoagulation. Dabigatran was ...
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36 Pradaxa (Dabigatran Etexilate Mesylate) - RxList
https://www.rxlist.com/pradaxa-drug.htm
RE-MEDY was an active-controlled study (warfarin) in which 1430 patients received PRADAXA 150 mg twice daily following 3 to 12 months of oral anticoagulant ...
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37 Treatment with dabigatran or warfarin in patients with venous ...
https://www.thieme-connect.com/products/ejournals/pdf/10.1160/TH14-11-0977.pdf
Summary. The efficacy and safety of dabigatran for treatment of venous throm- boembolism (VTE) were demonstrated in two trials. It is unclear if the.
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38 Treatment options for venous thromboembolism - Europe PMC
https://europepmc.org/article/med/25506267
This first head-to-head study showed that GI bleeding occurred in 5.3% of patients in the dabigatran group compared with 4.8% of patients in the rivaroxaban ...
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39 Prothrombin Complex Concentrate Is Effective in Treating the ...
https://pubs.asahq.org/anesthesiology/article/123/6/1350/14105/Prothrombin-Complex-Concentrate-Is-Effective-in
Administration of hemostatic agents such as PCC and activated PCC has been proposed for treating the effects of dabigatran. ... The European Heart Rhythm ...
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40 Oral Thrombin Inhibitor Dabigatran Etexilate vs North ...
https://www.arthroplastyjournal.org/article/S0883-5403(08)00067-3/abstract
* Treatment period: from administration of first dose of study medication and ending 3 days after administration of last dose of study ...
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41 FDA approves Pradaxa to treat DVT, PE - Healio
https://www.healio.com/news/cardiology/20140407/fda-approves-pradaxa-to-treat-dvt-pe
The RE-MEDY trial of patients previously treated for acute DVT and PE with 3 months to 12 months of anticoagulant therapy showed noninferiority ...
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42 RE-COVERY DVT/PE: Rationale and design of a prospective ...
https://vte.garfieldregistry.org/wp-content/uploads/2016/07/RE-COVERY-Design-Ageno-et-al-Thromb-Haemost.pdf
observational study of acute venous thromboembolism with a focus on dabigatran etexilate ... In the RE-MEDY trial, dabigatran was compared to warfarin in.
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43 Six months versus two years of oral anticoagulation after a first ...
https://www.haematologica.org/article/view/8979
REMEDY Trial Investigators; RE-SONATE Trial Investigators. Extended use of dabigatran, warfarin, or placebo in venous thromboembolism.
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44 Venous thromboembolism: current management
https://www.nps.org.au/australian-prescriber/articles/venous-thromboembolism-current-management
Dabigatran is approved for the treatment of venous thromboembolism, ... Clinical trials of anticoagulation for distal deep vein thrombosis ...
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45 Direct Oral Anticoagulants for the Treatment of Venous ...
https://www.ottawaheart.ca/sites/default/files/uploads/documents/Researchers/gwells-doac-vte-scientific-report-2015-2016.pdf
discontinued treatment. Dabigatran, but not apixaban (2.5 or 5 mg), rivaroxaban or ASA, was better ... Table 16: Study Characteristics —EXTENDED treatment .
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46 Antithrombotic Management of Venous Thromboembolism
https://emergency-department.com/wp-content/uploads/2021/02/9.-Management-of-VTE.pdf
As in its initial VTE treatment trial program, dabigatran performed as well as warfarin in reducing recurrent VTE and had similar rates of major bleeding.
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47 Review Article Current Status of New Anticoagulants in the ...
https://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=1d204601a6afcd56ab0373dd77f695e5f026a26d
(d) RESONATE is a phase III clinical trial that, like. REMEDY, evaluates the use of dabigatran as treatment of. VTE for an extended period of time.
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48 peer review - F1000Research
https://f1000research.com/articles/6-985/v1/pdf
RE-MEDY trial (Dabigatran or Warfarin for Extended Maintenance. Therapy of Venous Thromboembolism)16, and rivaroxaban was.
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49 Clinical Trials - ScienceMedia
https://www.sciencemedia.com/t/Clinical_trials/
Clinical Trial diagnosis, pathophysiology, and treatments in SMi Source. ... Dabigatran Clinical Trials: Summary. Dabigatran Clinical Trials: Summary.
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50 New oral anticoagulants – a review
https://tidsskriftet.no/en/2013/10/new-oral-anticoagulants-review
Anticoagulation treatment is necessary for preventing and treating a ... In the one study (RE-SONATE) dabigatran was compared with a placebo ...
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51 Optimizing Stroke Prevention in Patients With Atrial Fibrillation
https://www.cdc.gov/pcd/issues/2016/16_0078.htm
The inability of CARAT to recommend a NOAC as a treatment option or provide practical advice to clinicians about the suitability of dabigatran ...
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52 Dabigatran Etexilate, Relacorilant - Clinical Trials Registry
https://ichgcp.net/clinical-trials-registry/NCT05347979
Participants will receive a single dose of dabigatran etexilate before and after administration of daily (QD) doses of relacorilant for 11 days. As all ...
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53 Comparisons between Novel Oral Anticoagulants and Vitamin ...
https://jasn.asnjournals.org/content/25/3/431
We excluded 19 other randomized controlled trials (RCTs). Two had results that were embargoed (Long-Term Multicenter Extension of Dabigatran Treatment in ...
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54 Oral direct thrombin inhibitors or oral factor Xa inhibitors for ...
https://www.journalslibrary.nihr.ac.uk/downloads/other-nihr-research/cochrane-programme-grants/Oral-direct-thrombin-inhibitors.pdf
We included 11 randomised controlled trials of 27,945 participants. Three studies tested oral DTIs (two dabigatran and one ximelaga-.
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55 Pulmonary Embolism Diagnosis & Treatment Guideline
https://wa.kaiserpermanente.org/static/pdf/public/guidelines/pulmonary-embolism.pdf
Tinzaparin vs Warfarin for Treatment of Acute Venous. Thromboembolism in Patients With Active Cancer: A Randomized Clinical Trial. JAMA. 2015 Aug 18;314(7):677- ...
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56 Prevention and treatment of venous thromboembolism ... - Gale
https://go.gale.com/ps/i.do?id=GALE%7CA379428749&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=20901488&p=AONE&sw=w
However, the REMEDY trial revealed that dabigatran was less effective and associated with more acute coronary events compared to warfarin when given for an ...
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57 Prediction of rates of thromboembolic and major bleeding ...
https://www.jstor.org/stable/26945665
Recent randomized controlled trials provide estimates of risk for thromboembolism and major bleeding under treatment with dabigatran or warfarin within low,.
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58 PRADAXA 150 - Dabigatran Etexilate 150 mg
https://www.pharmaline.co.il/wp-content/uploads/2022/02/PRADAXA-150-24.2D.pdf
Renal function should be assessed during treatment with dabigatran etexilate at ... In the RE-SONATE study, which compared dabigatran etexilate to placebo, ...
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59 Pradaxa (dabigatran): Uses, side effects, dosage, and more
https://www.medicalnewstoday.com/articles/pradaxa
In another study, Pradaxa was compared with a placebo (treatment with no active drug) to help prevent DVT or PE in people who had one in the past.
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60 Pradaxa Oral: Uses, Side Effects, Interactions ... - WebMD
https://www.webmd.com/drugs/2/drug-154839/pradaxa-oral/details
These drugs may increase the risk of bleeding problems if taken during treatment with dabigatran. Carefully check all prescription/nonprescription product ...
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61 REV_ISS_WEB_JAH3_342_2-5 1..12 - The Fritsma Factor
https://fritsmafactor.com/sites/default/files/attachments/2014/01/jah3-2-e000136.pdf
double-blind RE-COVER (Efficacy and Safety of Dabigatran. Compared to Warfarin for 6 Month Treatment of Acute. Symptomatic Venous Thromboembolism) trial.
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62 Bleeding Events Among New Starters and Switchers to ...
https://www.amjmed.com/article/S0002-9343(14)00126-0/abstract
The average follow-up time was 13 months. Across the 6 combinations of treatment (dabigatran 110 mg, dabigatran 150 mg, and warfarin) and VKA experience status ...
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63 Deep vein thrombosis: pathogenesis, diagnosis, and medical ...
https://cdt.amegroups.com/article/view/16872/18087
The effectiveness of dabigatran for treatment of DVT has been confirmed in three recent double-blind randomized controlled trials: RE-COVER, REMEDY, ...
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64 The most important abstracts relating to thrombosis and ...
https://www.stoptheclot.org/news/article219/
Abstract #1: This large, 2,539 patient phase 3 trial on “Dabigatran in the Treatment of Venous Thromboembolism” (REMEDY trial) was appropriately deemed to ...
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65 Is it time for home treatment of pulmonary embolism?
https://erj.ersjournals.com/content/40/3/742
Dabigatran, a direct oral thrombin inhibitor, has been compared with warfarin in patients with acute symptomatic VTE. The RE-COVER study, published in 2009, was ...
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66 Novel Oral Anticoagulants for Stroke Prophylaxis and Venous ...
https://institutionalrepository.aah.org/cgi/viewcontent.cgi?article=1055&context=jpcrr
RE-COVER II trials, dabigatran was shown to have similar efficacy to warfarin in the treatment of VTE.6,7. In the REMEDY (vs. warfarin) and ...
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67 DOACs for the treatment of VTE and prevention of recurrent VTE
https://www.pulsetoday.co.uk/sponsored/managing-and-treating-patients-with-vte/treatment-of-vte/doacs-for-the-treatment-of-vte-and-prevention-of-recurrent-vte/
Both trials had a randomised, double-blind, double-dummy design to compare dabigatran 150 mg twice daily with warfarin, adjusted to maintain an INR of 2.0 to ...
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68 New anticoagulants for the treatment of venous ... - SciELO
https://www.scielo.br/j/jbpneu/a/yCDKLsbJkMvWH8J6KbKThff/?lang=en
The recommended dose for VTE treatment with dabigatran, following a 5-day course of parenteral or subcutaneous anticoagulation, is 150 mg every 12 h. If the ...
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69 Venous Thromboembolism in Cancer: An Update of Treatment ...
https://www.frontiersin.org/articles/10.3389/fcvm.2016.00024/full
Dabigatran etexilate is the most developmentally advanced oral direct thrombin inhibitor. In randomized, double-blinded trials, it has been ...
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70 Atrial fibrillation - Treatment - NHS
https://www.nhs.uk/conditions/atrial-fibrillation/treatment/
Depending on your level of risk, you may be prescribed warfarin or an anticoagulant, such as dabigatran, rivaroxaban, apixaban or edoxaban. If you're prescribed ...
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71 A Practical Update for Clinician - Semantic Scholar
https://pdfs.semanticscholar.org/7bb7/b134d4bb83177f5428632cf558a77e13a1ad.pdf
In the REMEDY study, patients with VTE who had completed 3–12 months of anticoagulant therapy were randomized to treatment with dabigatran ...
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72 The safe and effective use of dabigatran and warfarin in ...
https://bpac.org.nz/2017/anticoagulants.aspx
A trial of treatment with a proton pump inhibitor (PPI) or an H2-receptor antagonist should be considered in patients with persistent dyspepsia.
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73 comparative risk of major bleeding with new oral antico
https://www.encepp.eu/encepp/openAttachment/studyResult/22062;jsessionid=XkqWuc_oImiXzZoYNx-6LkKjIHGmc4qY_cEc1FPQqKMN931OMKKm!310772498
Version identifier of the final study report Final ... treatment on the reduced dose (apixaban 2.5 mg, dabigatran 110mg, rivaroxaban 15mg) ...
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74 Steps toward simplifying the treatment of pulmonary embolism
https://www.openaccessjournals.com/articles/steps-toward-simplifying-the-treatment-of-pulmonary-embolism.pdf
These drugs (e.g., dabigatran, rivaroxaban, apixaban or edoxaban) have been compared with standard treatment in a number of Phase III clinical trials in ...
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75 PRODUCT MONOGRAPH PrTEVA-DABIGATRAN
https://pdf.hres.ca/dpd_pm/00043966.PDF
Out of 2,114 patients treated with dabigatran 150mg bid in recurrent DVT/PE prevention trials (RE-MEDY, RE-SONATE) (long-term treatment up ...
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76 Cost-Effectiveness of Dabigatran Compared to Vitamin-K ...
https://research.rug.nl/files/23591776/journal.pone.0135054.pdf
ysis of dabigatran compared to VKAs for DVT treatment was performed, using these estimates. Methods. A retrospective observational study design in the ...
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77 Antiplatelet and Anticoagulant Treatments for Unstable Angina ...
https://effectivehealthcare.ahrq.gov/products/angina-heart-attack-treatments/research-protocol
Inclusion of clinical trials comparing triple and dual antiplatelet therapy for the treatment of ACS, without requiring a long-term indication for ...
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78 Assesses and Informs - Fimea
https://www.fimea.fi/documents/160140/1153780/22874_KAI_4_2012_Executive_summary.pdf/1ec0b34d-4126-4a2c-894a-ddc7fb2061dc?t=1442574060391
In this trial, compared with warfarin, dabigatran 150 mg twice daily ... dabigatran discontinued study treatment more frequently than those on warfarin.
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79 Impact of Rabeprazole on APO-Dabigatran exposure in ...
https://www.cjcopen.ca/article/S2589-790X(22)00199-8/fulltext
The Treatment with APO-Dabigatran Absorption study was an open-label crossover study in 46 healthy male volunteers comparing the absorption ...
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80 Efficacy and Cost-Effectiveness of Dabigatran Etexilate Versus ...
https://thoracickey.com/efficacy-and-cost-effectiveness-of-dabigatran-etexilate-versus-warfarin-in-atrial-fibrillation-in-different-age-subgroups/
The Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial demonstrated the safety and efficacy of dabigatran versus warfarin ...
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81 peer review - AWS
https://f1000researchdata.s3.amazonaws.com/manuscripts/12057/4c9d592e-231b-4712-a8e7-9131196e4955_11174_-_jeffrey_weitz.pdf?doi=10.12688/f1000research.11174.1&numberOfBrowsableCollections=48&numberOfBrowsableInstitutionalCollections=4&numberOfBrowsableGateways=40
RE-MEDY trial (Dabigatran or Warfarin for Extended Maintenance. Therapy of Venous Thromboembolism)16, and rivaroxaban was.
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82 Economic appraisal of dabigatran as first-line therapy for ...
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742013000400020
At an ICER of R93 290, dabigatran proves cost-effective when compared with trial-like warfarin as a first-line treatment in patients with AF and at risk of ...
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83 Modern Management of Deep Venous Thrombosis
https://www.hmpgloballearningnetwork.com/site/vdm/content/modern-management-deep-venous-thrombosis
The REMEDY trial randomized 1,430 patients who had completed at least 3 months ... Recurrent VTE occurred in 1.8% of the dabigatran vs 1.3% of the warfarin ...
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84 Trial synopsis 1160.117_CO - MyStudyWindow
https://www.mystudywindow.com/DAM/253373/1160-0117/cf4e50e8-cadc-40b2-b2d0-ac7601827b17/1160-0117_synopsis.pdf
This clinical study synopsis is provided in line with Boehringer Ingelheim's ... test treatment T) with 150 mg of dabigatran etexilate ...
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85 (PDF) Treatment of Acute Venous Thromboembolism With ...
https://www.academia.edu/15530959/Treatment_of_Acute_Venous_Thromboembolism_With_Dabigatran_or_Warfarin_and_Pooled_Analysis
The design of this trial was essentially identical to that of the first study with dabigatran for the treatment of acute VTE.4 Briefly, ...
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86 Sobieraj-2015.pdf - Outcomes Research Consortium
http://www.or.org/bibliography/PDF/4183751353/Sobieraj-2015.pdf
dabigatran, rivaroxaban, idraparinux and VKAs all reduced VTE ... ysis safeguards the within-trial randomized treatment comparison of.
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87 Removal of Dabigatran by Hemodialysis
https://www.ajkd.org/article/S0272-6386(12)01395-9/abstract
However, using warfarin in the treatment of AF has a number of notable ... In the RE-LY trial, the 10th-90th percentile dabigatran trough ...
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88 Pradaxa and Xarelto: A Case Study in Evidence Based Medicine
https://www.youtube.com/watch?v=WbeNbIctGyU
Strong Medicine
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89 Antithrombotics For Treatment of Outpatient COVID-19 – St ...
http://stjoesemresidency.com/the-activ-4b-trial-antithrombotics-for-treatment-of-outpatient-covid-19/
Investigators of the ACTIV-4b trial sought to answer this question. Article: Connors, J. M. et al. Effect of antithrombotic therapy on clinical ...
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90 3 Trials That Will Change Your Practice|ESC 22
https://www.aerjournal.com/video-index/esc-22-3-trials-will-change-your-practice-dr-afzal-sohaib
Arrhythmia & Electrophysiology Review
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91 Micromedex Products: Please Login
https://www.micromedexsolutions.com/micromedex2/librarian
- Evidence based clinical resources to support informed diagnosis and treatment decisions. - Unbiased, referenced Clinical Decision Support (CDS) for medication ...
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92 Cleveland Clinic Trial Finds Six Widely Used Dietary ...
https://newsroom.clevelandclinic.org/2022/11/06/cleveland-clinic-trial-finds-six-widely-used-dietary-supplements-do-not-lower-cholesterol-compared-with-either-a-low-dose-statin-or-placebo/
Patients came for treatment from every state and 185 countries. Visit us at clevelandclinic.org. Follow us at twitter.com/ClevelandClinic. News ...
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93 Anticoagulation Therapy - Page 89 - Google Books Result
https://books.google.com/books?id=6tlVDwAAQBAJ&pg=PA89&lpg=PA89&dq=remedy+dabigatran+trial&source=bl&ots=GlOSPONCTB&sig=ACfU3U3CKmwrGn1JwBS3lPn2ApPFwHZVQg&hl=en&sa=X&ved=2ahUKEwjim5X5jM37AhXOQEEAHTSGAvMQ6AF6BQirAhAD
Table 5.1 Dabigatran versus warfarin (INR 2–3) for thromboprophylaxis in ... In the VTE treatment and secondary prevention trials comparing dabigatran with ...
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