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1 BG-12 in multiple sclerosis - PubMed
https://pubmed.ncbi.nlm.nih.gov/23709213/
BG-12 is an orally administered, enteric-coated microtablet preparation of DMF. In two phase III, relapsing-remitting multiple sclerosis (MS) trials, BG-12 led ...
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2 Dimethyl fumarate (BG-12) first line oral treatment for people ...
https://www.cochrane.org/CD011076/MS_dimethyl-fumarate-bg-12-first-line-oral-treatment-for-people-with-multiple-sclerosis
Dimethyl fumarate (BG-12) first line oral treatment for people with multiple sclerosis ... Dimethyl fumarate was approved by the U.S. Food and ...
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3 Oral BG-12 (Dimethyl Fumarate) Significantly Reduced ...
https://investors.biogen.com/news-releases/news-release-details/oral-bg-12-dimethyl-fumarate-significantly-reduced-multiple
BG-12 (dimethyl fumarate) is an investigational oral therapy in late-stage clinical development for the treatment of RRMS, the most common form ...
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4 Use of DMF in MS (Tecfidera, BG-12) - Cleveland Clinic
https://my.clevelandclinic.org/departments/neurological/depts/multiple-sclerosis/ms-approaches/use-dmf-in-ms
A: Dimethyl fumarate (DMF, Tecfidera) was approved by the US FDA in March 2013 as an oral disease modifying treatment for relapsing forms of MS.
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5 BG-12 in Multiple Sclerosis - Thieme Connect
https://www.thieme-connect.com/products/ejournals/pdf/10.1055/s-0033-1343796.pdf
For almost 20 years, disease-modifying therapies have been available for treatment of relapsing forms of multiple sclero- sis (MS).
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6 FDA Approves Twice a Day Capsules Called Tecfidera ...
https://www.nationalmssociety.org/About-the-Society/News/FDA-Approves-Twice-a-Day-Capsules-Called-Tecfidera
FDA Approves Twice a Day Capsules Called Tecfidera™ (formerly called BG-12) for Relapsing MS · FAQ About FDA's Approval of Oral Dimethyl Fumarate ...
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7 BG-12 (dimethyl fumarate) in the treatment of multiple sclerosis
https://www.openaccessjournals.com/articles/bg12-dimethyl-fumarate-in-the-treatment-of-multiple-sclerosis.pdf
become a valuable treatment option for multiple sclerosis patients and neurologists. Keywords: BG-12 • clinical development • dimethyl fumarate • emerging ...
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8 Dimethyl fumarate (BG-12) for the treatment of multiple sclerosis
https://www.tandfonline.com/doi/full/10.1586/17512433.2013.811826
Dimethyl fumarate is the active compound of BG-12 recently licensed for the treatment of relapsing–remitting MS. The pivotal Phase III ...
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9 Efficacy and Safety of Oral BG00012 in Relapsing-Remitting ...
https://clinicaltrials.gov/ct2/show/NCT00420212
To determine if treatment with BG00012 can decrease the number of MS relapses during a certain time period. To determine if, over time, BG00012 treatment ...
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10 Tecfidera, BG-12 (dimethyl fumarate) dosing, indications ...
https://reference.medscape.com/drug/tecfidera-bg-12-dimethyl-fumarate-999810
Medscape - Multiple sclerosis dosing for Tecfidera, BG-12 (dimethyl ... Consider withholding treatment in patients with serious infections until the ...
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11 Pharmacology and clinical efficacy of dimethyl fumarate (BG ...
https://www.dovepress.com/pharmacology-and-clinical-efficacy-of-dimethyl-fumarate-bg-12-for-trea-peer-reviewed-fulltext-article-TCRM
Pharmacology and clinical efficacy of dimethyl fumarate (BG-12) for treatment of relapsing–remitting multiple sclerosis Serena Ruggieri,1 ...
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12 Effects of BG-12 (dimethyl fumarate) on health-related quality ...
https://journals.sagepub.com/doi/10.1177/1352458513507818
Oral BG-12 (dimethyl fumarate) is approved in the United States for the treatment of relapsing forms of MS and is undergoing regulatory ...
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13 Pill Found Promising in Treatment of MS - The New York Times
https://www.nytimes.com/2012/09/20/health/research/bg-12-pill-shows-promise-in-suppressing-multiple-sclerosis-relapses.html
The two new studies, published online in The New England Journal of Medicine, found that the drug BG-12, developed by Biogen Idec, reduced ...
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14 Tecfidera (Dimethyl Fumarate), Treatment for Relapsing ...
https://www.clinicaltrialsarena.com/projects/ms-treatment/
Tecfidera (BG-12/Dimethyl Fumarate) is a first-line oral treatment indicated for patients with relapsing-remitting multiple sclerosis (RRMS) ...
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15 Treatment of MS patients with BG-12 results in a decline in ...
https://www.jimmunol.org/content/192/1_Supplement/52.17
BG-12 (Tecfidera®) is a recently approved oral treatment for multiple sclerosis that has shown remarkable efficacy.
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16 BG-12 in Multiple Sclerosis | Request PDF - ResearchGate
https://www.researchgate.net/publication/236940315_BG-12_in_Multiple_Sclerosis
BG-12 is an orally administered, enteric-coated microtablet preparation of DMF. In two phase III, relapsing-remitting multiple sclerosis (MS) ...
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17 The Cost Effectiveness of BG-12 (Dimethyl Fumarate) for the ...
https://www.valueinhealthjournal.com/article/S1098-3015(13)03731-5/fulltext
Multiple sclerosis (MS) causes significant disability and diminished quality of life globally. BG-12 is a new oral treatment for relapsing forms of MS that ...
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18 Oral BG-12 for Relapsing-Remitting Multiple Sclerosis, Part I
https://academic.oup.com/book/24647/chapter/187994252
In patients with relapsing-remitting multiple sclerosis, oral BG-12 was shown to be an effective disease-modifying therapy compared to placebo. This finding ...
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19 Positive Results from Phase 3 CONFIRM Clinical Trial Show ...
https://biogen.gcs-web.com/news-releases/news-release-details/positive-results-phase-3-confirm-clinical-trial-show-efficacy
BG-12 also met magnetic resonance imaging (MRI) endpoints in a cohort of patients, demonstrating a significant effect on MS brain lesions.
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20 Pathway to Success? MS Drug Takes Nrf-2 Pathway for ...
https://practicalneurology.com/articles/2012-may-june/pathway-to-success-ms-drug-takes-nrf-2-pathway-for-treatment
BG-12 is an oral therapy under regulatory review in the US and Europe for the treatment of MS.
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21 The DEFINE trial: BG-12 reduces relapse rate in multiple ...
https://www.2minutemedicine.com/the-define-trial-bg-12-reduces-relapse-rate-in-multiple-sclerosis-classics-series/
In summary, BG-12 significantly reduces relapse rates of multiple sclerosis (MS) as compared to placebo (P<0.001), regardless of the ...
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22 Dimethyl fumarate treatment of relapsing-remitting multiple ...
https://nn.neurology.org/content/3/2/e211
Treatment of relapsing-remitting multiple sclerosis (RRMS) has advanced with the approval of new medications. ... BG-12 (Tecfidera; Biogen Idec, ...
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23 Disease-modifying therapies for multiple sclerosis - UpToDate
https://www.uptodate.com/contents/disease-modifying-therapies-for-multiple-sclerosis-pharmacology-administration-and-adverse-effects
○(See "Treatment of secondary progressive multiple sclerosis in adults".) ... Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple ...
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24 Fumaric Acid Dimethyl Ester - an overview - ScienceDirect.com
https://www.sciencedirect.com/topics/medicine-and-dentistry/fumaric-acid-dimethyl-ester
Dimethyl fumarate is the last oral treatment for MS, registered by the FDA 2 years ago with the trade name BG12. BG12 contains only dimethyl ester fumarate ...
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25 Tecfidera™, a New Oral medication for MS is approved by FDA!
https://www.hopkinsmedicine.org/neurology_neurosurgery/centers_clinics/multiple_sclerosis/_docs/tecfidera_information.pdf
This medication was known in clinical trials as “BG-12”. Tecfidera™ is the tenth disease-modifying therapy available for the treatment of MS ...
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26 Tecfidera - MS Society of Canada
https://mssociety.ca/managing-ms/treatments/medications/disease-modifying-therapies-dmts/tecfidera
Tecfidera (formerly known as BG-12) or dimethyl fumarate is an oral medication for the treatment of relapsing-remitting multiple sclerosis (MS).
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27 BG-12: New Oral Medication for Relapsing-remitting MS
https://www.reliasmedia.com/articles/78034-bg-12-new-oral-medication-for-relapsing-remitting-ms
Two recently reported Phase 3 trials for BG-12 demonstrated efficacy and safety in the treatment of relapsing-remitting multiple sclerosis.
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28 eMS News - Rocky Mountain MS Center
https://mscenter.org/education/ems-news/
Latest Guidance on COVID-19 Preventative & Treatment Options from the MS Center Medical Team ... The COVID-19 vaccines and boosters remain the best defense ...
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29 Emerging Understanding of the Mechanism of Action for ...
https://www.frontiersin.org/articles/10.3389/fneur.2018.00005/full
Dimethyl fumarate (DMF) is an effective treatment option for relapsing–remitting multiple sclerosis (MS), but its therapeutic mechanism of ...
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30 Studies: Psoriasis Medication Effective as MS Treatment
https://themobilityproject.com/articles/2012/09/25/bg12-ms-treatment-studies.aspx
Dimethyl fumarate, also known as BG-12, has been found to be an effective treatment for multiple sclerosis (MS) according to a pair of ...
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31 Timecourse of Treatment Effects of BG-12 (Dimethyl Fumarate ...
https://cmsc.confex.com/cmsc/2013/webprogram/Handout/Paper1353/DX40.pdf
Timecourse of Treatment Effects of BG-12 (Dimethyl Fumarate) in MS ... Weston, MA, USA; 6Mellen Center for Multiple Sclerosis Treatment and Research, ...
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32 BG-12 Shows Clinical, Neuroradiologic Efficacy in U.S. ...
https://www.hcplive.com/view/bg-12-shows-clinical-neuroradiologic-efficacy-in-us-patients-with-relapsingremitting-multiple-sclerosis-
Oral dimethyl fumarate (BG-12) is in development for the treatment of relapsing multiple sclerosis (MS), though experimental evidence ...
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33 The Effectiveness of Dimethyl Fumarate Monotherapy in the ...
http://www.eurekaselect.com/article/58644
Background: Dimethyl fumarate (BG-12, Tecfidera®) is a new oral drug approved by FDA and EMA in March 2013 for relapsing – remitting multiple sclerosis ...
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34 Biogen Idec Submits Application for BG-12 | MSAA
https://mymsaa.org/news/biogen-idec-submits-application-for-bg-12/
... for approval of BG-12 (dimethyl fumarate), an experimental oral drug for the treatment of relapsing-remitting multiple sclerosis (RRMS).
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35 Another Oral Therapy for Relapsing Multiple Sclerosis
https://www.jwatch.org/jn201210300000005/2012/10/30/another-oral-therapy-relapsing-multiple
Another Oral Therapy for Relapsing Multiple Sclerosis: Dimethyl Fumarate (BG-12). Jeffrey M. Gelfand, MD, reviewing Gold R et al.
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36 Oral BG-12 (Dimethyl Fumarate) significantly reduced multiple ...
https://www.europeanpharmaceuticalreview.com/news/9531/oral-bg-12-dimethyl-fumarate-significantly-reduced-multiple-sclerosis-ms-relapses-and-disability-progression/
“The significant clinical and radiological responses in DEFINE are further evidence that BG-12 may become an oral therapy of choice for MS ...
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37 BG-12 May Reduce Relapse Rate for Patients With MS
https://www.mdedge.com/neurology/article/73630/multiple-sclerosis/bg-12-may-reduce-relapse-rate-patients-ms
BG-12 (dimethyl fumarate) significantly reduced the annualized relapse rate among patients with multiple sclerosis (MS) compare.
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38 Dimethyl fumarate: a novel oral front-line therapy for multiple ...
https://www.futuremedicine.com/doi/abs/10.2217/fnl.13.11
Based on its favorable safety, tolerability and neuroprotective properties, BG-12 represents an excellent oral disease-modifying drug in the ...
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39 Biogen Idec's oral compound BG-12 achieves de - EurekAlert!
https://www.eurekalert.org/news-releases/733953
"The Phase IIb study of oral BG-12 in patients with MS showed promising MRI results regarding the compound's ability to reduce inflammation ...
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40 Disease-modifying therapies and infectious risks in multiple ...
https://www.nature.com/articles/nrneurol.2016.21
Dimethyl fumarate and fumaric acid esters. DMF (also known as BG12) is another oral treatment option for MS. In 2013, following the phase III ...
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41 Biogen: New data support BG-12 as MS treatment
https://www.marketwatch.com/story/biogen-new-data-support-bg-12-as-ms-treatment-2012-10-12
Most treatments for the chronic, inflammatory and potentially disabling disease are delivered by needle, but BG-12, or dimethyl fumarate, is an ...
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42 Tecfidera (dimethyl fumarate) - MS Trust
https://mstrust.org.uk/a-z/tecfidera-dimethyl-fumarate
Tecfidera (dimethyl fumarate) is a disease modifying drug treatment for relapsing remitting MS. You take Tecfidera as a pill twice a day.
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43 dimethyl fumarate Manufacturer1: Biogen Idec Inc. Drug ...
https://pharmacy.wvu.edu/media/1156/tecfidera-dimethyl-fumarate.pdf
effect in multiple sclerosis is unknown.1,2,3,4 It is believed to be through the Nrf2 ... The results for the BG-12 240 mg three times daily treatment group.
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44 Oral compound BG-12 achieves primary endpoint in phase II ...
http://test.pharmabiz.com/news/oral-compound-bg-12-achieves-primary-endpoint-in-phase-ii-study-of-relapsing-remitting-ms-33710
The study achieved its primary endpoint, demonstrating that treatment with BG-12 led to a statistically significant reduction in the total number of gadolinium- ...
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45 Biogen Idec's Tecfidera - Pharmacy Times
https://www.pharmacytimes.com/view/biogen-idecs-tecfidera
Tecfidera (dimethyl fumarate) has been approved by the FDA for the treatment of relapsing forms of multiple sclerosis.
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46 BG-12: New pill shows promise against relapsing multiple ...
https://medicalxpress.com/news/2012-09-bg-pill-relapsing-multiple-sclerosis.html
BG-12: New pill shows promise against relapsing multiple sclerosis ... The relapse rate was nearly halved after 2 years, researchers find. ( ...
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47 Pharmacology and clinical efficacy of dimethyl fumarate ... - Gale
https://go.gale.com/ps/i.do?id=GALE%7CA414272163&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=1178203X&p=HRCA&sw=w
... fumarate (BG-12) for treatment of relapsing-remitting multiple sclerosis ... The arsenal for MS therapy includes treatment of acute relapses with ...
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48 Pharmacology and clinical efficacy of ... - Semantic Scholar
https://pdfs.semanticscholar.org/9435/e3747a45d832b7c2281439b393096a0964bf.pdf
of dimethyl fumarate (BG-12) for treatment ... Multiple sclerosis (MS) is a chronic inflammatory immune-mediated disease of the.
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49 Case Number: 202002-125629
https://www.dfs.ny.gov/public-appeals/case-number-202002-125629
1) Fox RJ, Miller DH, Phillips JT, et al. "Placebo-controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis." N Engl J Med, 2012; 367:1087. 2) ...
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50 Current and Future Therapies for Multiple Sclerosis - Hindawi
https://www.hindawi.com/journals/scientifica/2013/249101/
Treatment with BG-12 is associated with low lymphocyte counts. The investigators concluded that treatment of patients with relapsing-remitting MS with BG-12 and ...
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51 Tecfidera (BG-12) awaits FDA decision - MS Living Well
https://www.mslivingwell.org/2013/01/29/tecfidera-bg-12-awaits-fda-decision/
Tecfidera (BG-12) is pending FDA decision on March 27, 2013. This oral twice daily treatment for multiple sclerosis has been demonstrated to ...
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52 Biogen's MS Drug Tecfidera Wins FDA Nod | MedPage Today
https://www.medpagetoday.com/neurology/multiplesclerosis/38122
Manufactured by Biogen Idec, the drug is also known as BG-12. It becomes the third oral disease-modifying medication available to treat MS.
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53 Monomethyl Fumarate (MMF, Bafiertam) for the Treatment of ...
https://www.mdpi.com/2035-8377/13/2/22/htm
Monomethyl fumarate (MMF, Bafiertam) is a recent addition to the arsenal available in the fight against MS and appears to be well-tolerated, safe, and effective ...
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54 Effect of Dimethyl Fumarate vs Interferon β-1a in Patients With ...
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2796813
... interferon β-1a for treatment of pediatric-onset multiple sclerosis. ... phase 3 study of oral BG-12 for relapsing multiple sclerosis.
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55 Oral BG-12 or Glatiramer Acetate for Multiple Sclerosis
https://www.hmpgloballearningnetwork.com/site/frmc/articles/oral-bg-12-or-glatiramer-acetate-multiple-sclerosis
Parenteral agents (interferon beta and glatiramer acetate) are common treatments for multiple sclerosis (MS), a chronic demyelinating and neurodegenerative ...
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56 Experimental MS Pill Continues to Show Promise - WebMD
https://www.webmd.com/multiple-sclerosis/news/20120919/experimental-ms-pill-continues-show-promise
In two late-phase studies appearing in The New England Journal of Medicine, the drug BG-12 (dimethyl fumarate) reduced relapses by about half in ...
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57 HIGHLIGHTS OF PRESCRIBING INFORMATION - Tecfidera
https://www.tecfidera.com/content/dam/commercial/tecfidera/pat/en_us/pdf/full-prescribing-info.pdf
TECFIDERA is indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include ... printed with “BG-12 240 mg” in black ink on the body.
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58 The changing fortunes of dimethyl fumarate
https://hospitalpharmacyeurope.com/news/editors-pick/the-changing-fortunes-of-dimethyl-fumarate/
Dimethyl fumarate was found to be the most active of the esters and has now been investigated as a novel therapy for multiple sclerosis (MS). On ...
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59 Tecfidera (Dimethyl Fumarate), a New Oral Therapy Approved ...
https://www.ahdbonline.com/issues/2014/march-2014-volume-7-special-feature-fifth-annual-payers-guide-to-new-fda-approvals/1731-tecfidera-dimethyl-fumarate-a-new-oral-therapy-approved-by-the-fda-for-the-treatment-of-relapsing-forms-of-multiple-sclerosis
The symptoms of MS can vary widely, depending on which nerves are ... Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis.
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60 Biogen's Tecfidera Now The Most Prescribed Oral MS ...
https://multiplesclerosisnewstoday.com/multiple-sclerosis-news/2015/07/27/biogens-tecfidera-now-prescribed-oral-ms-therapy-globally/
Tecfidera (dimethyl fumarate, formerly known as BG-12) is Biogen's blockbuster oral therapy for treatment of relapsing forms of Multiple ...
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61 Biogen Idec lays out a convincing blockbuster case for MS pill ...
https://www.fiercebiotech.com/r-d/biogen-idec-lays-out-a-convincing-blockbuster-case-for-ms-pill-bg-12
Scientists published the results from the two big Phase III studies for BG-12 (dimethyl fumarate), demonstrating that both of the treatment regimens studied in ...
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62 Oral Therapies
http://www.ms.pitt.edu/diseasemanagement/disease-modifying-medications/oral-therapies
Tecfidera, generic name dimethyl fumarate, is FDA-approved to help control relapsing forms of Multiple Sclerosis (MS). This medication was known as BG-12 ...
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63 Customizing MS Therapy to the Individual
https://www.ajmc.com/view/choosing-the-right-ms-treatment-by-customizing-therapy-to-the-individual
With more multiple sclerosis (MS) treatments becoming available, ... risk reduction of 67% when treated with oral BG-12 (dimethyl fumarate), ...
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64 Tecfidera, INN-dimenthyl fumarate
https://www.ema.europa.eu/en/documents/product-information/tecfidera-epar-product-information_en.pdf
Green gastro-resistant hard capsules, size 0, printed with 'BG-12 240 mg' containing ... dysfunction and, if so, whether these symptoms are typical of MS or ...
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65 Placebo-Controlled Phase 3 Study of Oral BG-12 for ...
https://ms.biogenpro.no/content/dam/intl/europe/norway/ms/biogenpro/no_NO/documents/legemidler-page/tecfidera/artikler-og-studie/nejmoa_1114287_define_tecfidera.pdf
All patients were eligible to switch to an alter- native therapy for multiple sclerosis if they had completed 48 weeks of the study treatment ...
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66 remitting ms patients - Journal of the Neurological Sciences
https://www.jns-journal.com/article/S0022-510X(13)01657-2/pdf
12 treatment or new to BG-12 treatment in ENDORSE. Results: This analysis included ... any group) were MS relapse and nasopharyngitis for the continuing.
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67 BG-12 (dimethyl fumarate): a review of mechanism of action ...
https://europepmc.org/article/med/24131282
Multiple sclerosis (MS) is a chronic inflammatory disease, affecting more than 2.5 million people worldwide with more 400,000 cases in the United States alone.
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68 Tecfidera - Drug Therapy Guidelines
https://www.bcbswny.com/content/dam/COMMON/non-secure/provider/drug-therapy-guidelines/T-U-V/tecfidera.pdf
Tecfidera (studied as BG-12) is quickly metabolized in the GI-tract to the active ... oxidative stress are considered central factors in multiple sclerosis.
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69 Multiple Sclerosis (MS) Medications - RxList
https://www.rxlist.com/multiple_sclerosis_ms_medications/drugs-condition.htm
One advantage of glatiramer acetate treatment is that it has somewhat of a milder side effect profile and does not produce flu-like symptoms, fatigue, or ...
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70 FDA Approves Dimethyl Fumarate for Treatment of Relapsing ...
https://rhochistj.org/RhoChiPost/fda-approves-dimethyl-fumarate-treatment-relapsing-forms-multiple-sclerosis/
Fox, R. J., Miller, D. H., Phillips, J. T, et al;(2012). Placebo-Controlled Phase 3 Study of Oral BG-12 or Glatiramer in Multiple Sclerosis. New ...
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71 Oral Therapies for Multiple Sclerosis
http://perspectivesinmedicine.cshlp.org/content/9/1/a032011.full
Until now, the four orally available medications, fingolimod, dimethylfumarate (BG-12), teriflunomide, and cladribine have received market ...
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72 BG-12 Cuts Relapse Rate, Lesions in Multiple Sclerosis - Oruen
https://www.oruen.com/neurology/multiple-sclerosis/bg-12-cuts-relapse-rate-lesions-in-multiple-sclerosis
Even so, the two studies indicate that dimethyl fumarate, also known as BG-12, “has a future as an oral therapeutic option for patients with ...
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73 Tecfidera: Package Insert / Prescribing Information - Drugs.com
https://www.drugs.com/pro/tecfidera.html
Tecfidera is indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, ...
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74 Established and novel disease‐modifying treatments in ...
https://onlinelibrary.wiley.com/doi/full/10.1111/joim.12203
Abstract Multiple sclerosis (MS) is a presumed autoimmune disorder of the central nervous system, resulting in ... Dimethyl fumarate (BG-12).
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75 Comparative effectiveness of dimethyl fumarate versus ...
https://www.msard-journal.com/article/S2211-0348(18)30356-0/pdf
availability of multiple DMTs for the treatment of MS, treatment deci- ... Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis.
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76 Tecfidera: Side effects, dosage, uses, and more
https://www.medicalnewstoday.com/articles/325954
Tecfidera is classified as a disease-modifying therapy for MS. ... Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis. DOI:
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77 Tecfidera (Dimethyl fumarate) for Multiple Sclerosis
https://www.mymsteam.com/treatments/tecfidera
Some people may also know Tecfidera by its former name, BG-12. Tecfidera is not a cure for MS, but it can decrease the number of flare-ups and may help ...
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78 Tecfidera (dimethyl fumarate) - Rare Disease Advisor
https://www.rarediseaseadvisor.com/therapies/tecfidera-dimethyl-fumarate/
Tecfidera (dimethyl fumarate) is a disease-modifying agent by Biogen for the treatment of adults with relapsing-remitting multiple sclerosis ...
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79 Multiple Sclerosis Treatment BG-12 vs Protandim NRF2
https://www.youtube.com/watch?v=z7NNOkSR23I
Tecfidera™ (BG-12) is an oral formulation of the fumaric acid esters (FAE), containing the active metabolite dimethyl fumarate (DMF).
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80 BG12 Drug Awaits Approval - MS Ireland
https://www.ms-society.ie/research/latest-news-research/bg12-drug-awaits-approval
BG-12 (also know as dimethyl fumarate) a new experimental oral drug therapy for the treatment of relapsing remitting MS (RRMS), ...
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81 Dimethyl fumarate for relapsing-remitting multiple sclerosis - DOI
https://doi.org/10.1136/dtb.2014.9.0279
For many years the only drugs licensed for the treatment of multiple ... Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis.
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82 Dimethyl Fumarate | International Journal of MS Care
https://meridian.allenpress.com/ijmsc/article/19/2/74/33371/Dimethyl-FumarateA-Review-of-Efficacy-and
Results: Before starting DMF therapy, patients should receive counseling on ... Placebo-controlled phase 3 study of oral BG-12 for relapsing ...
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83 Oral Agents for Treating Multiple Sclerosis - U.S. Pharmacist
https://www.uspharmacist.com/article/oral-agents-for-treating-multiple-sclerosis
Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis. N Engl J Med. 2012;367:1098-1107. 6. Fox RJ, Miller DH, ...
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84 Oral Disease-Modifying Therapies for Multiple Sclerosis
https://thejcn.com/DOIx.php?id=10.3988/jcn.2015.11.1.9
multiple sclerosis; oral drug; clinical trial; treatment ... In a second phase II study of BG-12, treatment with 240 mg of BG-12 three times ...
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85 1 Introduction: Multiple sclerosis (MS) is an autoimmune ...
https://www.aphafoundation.org/sites/default/files/ckeditor/files/LezinaD%20APha%20Final.pdf
Patients diagnosed with MS experience a variety of symptoms ... phase 3 study of oral BG-12 or glatiramer in multiple sclerosis. N Engl J Med.
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86 MS treatment hopes - PMLiVE
https://www.pmlive.com/pharma_news/ms_treatment_hopes_146998
Three drugs are currently in fast-track development for MS. Biogen Idec is developing BG 12 (dimethyl fumarate) as an oral capsule for the ...
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87 [Tecfidera® (delayed-release dimethylfumarate) in the ...
http://journals.seedmedicalpublishers.com/index.php/FE/article/view/1320
Efficacy and safety of BG-12 (dimethyl fumarate) and other disease-modifying therapies for the treatment of relapsing-remitting multiple sclerosis: a ...
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88 Pharmacology and clinical efficacy of dimethyl fumarate (BG ...
http://www.osvahpharma.com/fa/Article/print/%D9%88%DB%8C%DA%98%D9%87%20%D9%BE%D8%B2%D8%B4%DA%A9%D8%A7%D9%86/%DA%A9%D9%84%DB%8C%D9%87%20%D9%85%D9%82%D8%A7%D9%84%D8%A7%D8%AA/184/Pharmacology%20and%20clinical%20efficacy%20of%20dimethyl%20fumarate%20(BG-12)%20for%20treatment%20of%20relapsing%E2%80%93remitting%20multiple%20sclerosis
Pharmacology and clinical efficacy of dimethyl fumarate (BG-12) for treatment of relapsing–remitting multiple sclerosis. Abstract
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89 Tecfidera (BG-12) Nrf2 Activator Approved by FDA for Multiple ...
https://www.nrf2.com/tecfidera-nrf2-activator-approved-by-fda-for-multiple-sclerosis-ms-treatment/
Although there is no treatment that will cure Multiple Sclerosis, there are three oral medications approved by the FDA to be a first-line treatment to slow ...
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90 Positive Results Reported for Biogen Idec's Oral MS Drug in ...
https://www.genengnews.com/news/positive-results-reported-for-biogen-idecs-oral-ms-drug-in-first-phase-iii-study/
Define trial results showed two-year treatment with BG-12 significantly reduced relapse rate and development of new lesions.
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91 Future MS treatments - MS International Federation
https://www.msif.org/news/2015/03/16/future-ms-treatments/
Dimethyl fumarate, also called BG12 and Tecfidera, has recently been approved in the USA, Australia, Canada and the European Union as a ...
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92 Tecfidera covid
https://tfp-lannion-22.fr/tecfidera-covid.html
Biogen's total sales in the US for the 12 months ending 30 June 2020, ... formerly known as BG-12) is the third orally-active MS treatment to be registered ...
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