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1 Targeted Drug Therapy | Breast Cancer Treatment
https://www.cancer.org/cancer/breast-cancer/treatment/targeted-therapy-for-breast-cancer.html
Margetuximab (Margenza): This HER2 monoclonal antibody can be used along with chemo to treat advanced breast cancer, typically after at least 2 other drugs that ...
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2 Treatment Options for HER2-Positive Breast Cancer - WebMD
https://www.webmd.com/breast-cancer/her2-positive-treatments
Trastuzumab (Herceptin) was the first targeted therapy approved by the FDA for HER2+ breast cancer. It's a type of biologic drug called a ...
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3 HER2 positive breast cancer: What it is, diagnosis and treatment
https://www.mdanderson.org/cancerwise/her2-positive-breast-cancer--what-it-is--diagnosis-and-treatment.h00-159542112.html
› cancerwise › her2-positi...
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4 Targeted Therapies for HER2-Positive Early Breast Cancer
https://www.komen.org/breast-cancer/treatment/type/her2-targeted-therapies/trastuzumab/
Neratinib is used to treat HER2-positive early breast cancer in some women who have completed treatment with trastuzumab (Herceptin). Treatment with neratinib ...
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5 What Are Anti-HER2 Therapies? - Breastcancer.org
https://www.breastcancer.org/treatment/targeted-therapy/what-are-anti-her2-therapies
Anti-HER2 therapies (also called HER2 inhibitors or HER2-targeted therapies) are a class of medicines used to treat all stages of ...
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6 New Treatments Emerge for Metastatic HER2+ Breast Cancer
https://www.cancer.gov/news-events/cancer-currents-blog/2020/tucatinib-trastuzumab-deruxtecan-her2-positive-metastatic-breast-cancer
Drugs like trastuzumab and pertuzumab (Perjeta) are monoclonal antibodies that bind to the HER2 protein above the cancer cell's surface, ...
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7 Anti-HER2 Therapy for Breast Cancer - Johns Hopkins Medicine
https://www.hopkinsmedicine.org/kimmel_cancer_center/cancers_we_treat/breast_cancer_program/treatment_and_services/survivorship/anti_her2_therapy.html
For a woman whose tumor contains a specific tumor marker called HER2 (human epidermal growth receptor 2), physicians may recommend a therapy called ...
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8 Targeted cancer drugs for breast cancer
https://www.cancerresearchuk.org/about-cancer/breast-cancer/treatment/breast-targeted-cancer-drugs
This treatment is made up of 2 drugs, trastuzumab, and a chemotherapy drug called deruxtecan. You might have this if you have HER2 positive breast cancer that:.
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9 The Changing Paradigm for the Treatment of HER2-Positive ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464074/
In patients with HER2+ metastatic breast cancer, four HER2-directed therapies are approved (herceptin, pertuzumab, kadcyla or lapatinib). For ...
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10 HER2-positive breast cancer: What is it? - Mayo Clinic
https://www.mayoclinic.org/breast-cancer/expert-answers/faq-20058066
Certain standard chemotherapy drugs also can be effective in treating HER2 -positive breast cancers, although these drugs don't specifically target the HER2 ...
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11 Current and Future Management of HER2-Positive Metastatic ...
https://ascopubs.org/doi/full/10.1200/op.21.00172
The combination of trastuzumab and pertuzumab and a single-agent chemotherapeutic should be the standard first-line treatment for most patients ...
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12 FDA Approves First Targeted Drug To Treat HER2-Low Breast ...
https://www.mskcc.org/news/trastuzumab-deruxtecan-t-dxd-treating-her2-low-breast-cancer
Trastuzumab (Herceptin®) was the first targeted therapy developed to treat HER2-positive patients. “HER2-positive,” which accounts for 15% to 20 ...
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13 Treatment for HER2-Positive Breast Cancer - Healthline
https://www.healthline.com/health/breast-cancer/chemotherapy-for-her2-positive-breast-cancer
Trastuzumab (Herceptin) and pertuzumab (Perjeta) are the most commonly used drugs used to treat HER2-positive breast cancer. Neratinib (Nerlynx) ...
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14 FDA Approves First Targeted Therapy for HER2-Low Breast ...
https://www.fda.gov/news-events/press-announcements/fda-approves-first-targeted-therapy-her2-low-breast-cancer
FDA Approves First Targeted Therapy for HER2-Low Breast Cancer ... Today, the U.S. Food and Drug Administration approved Enhertu (fam-trastuzumab- ...
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15 Breast Cancer - Metastatic: Types of Treatment
https://www.cancer.net/cancer-types/breast-cancer-metastatic/types-treatment
For men with metastatic hormone receptor-positive, HER2-negative breast cancer, ASCO recommends hormonal therapy with tamoxifen. Other options include an AI ...
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16 HER2+ Cancer Treatment Option | Herceptin® (trastuzumab)
https://www.herceptin.com/
Herceptin alone is approved for the treatment of HER2-positive breast cancer in patients who have received one or more chemotherapy courses for metastatic ...
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17 Trastuzumab Deruxtecan in Previously Treated HER2-Low ...
https://www.nejm.org/doi/full/10.1056/NEJMoa2203690
Abstract Background Among breast cancers without human epidermal growth factor receptor 2 (HER2) amplification, overexpression, or both, ...
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18 Herceptin (trastuzumab) - NHS
https://www.nhs.uk/conditions/herceptin/
When herceptin is used · early-stage HER2 positive breast cancer, following surgery and/or radiotherapy and chemotherapy, to reduce the risk of the cancer coming ...
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19 Targeted therapy for breast cancer | Canadian Cancer Society
https://cancer.ca/en/cancer-information/cancer-types/breast/treatment/targeted-therapy
Trastuzumab is the most common targeted therapy drug used to treat HER2-positive breast cancer. It is given through a needle in a vein (intravenously).
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20 Management of Early-Stage HER2-Positive Breast Cancer
https://www.cancernetwork.com/view/management-early-stage-her2-positive-breast-cancer
Dr. Hurvitz: The standard of care to treat curable HER2-positive breast cancer has been to give chemotherapy with the HER2-targeted monoclonal ...
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21 HER2 therapy: Molecular mechanisms of trastuzumab ...
https://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr1612
Trastuzumab is a monoclonal antibody targeted against the HER2 tyrosine kinase receptor. The majority of patients with metastatic breast ...
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22 FDA Approves New Treatment for HER2-positive Breast Cancer
https://www.aacr.org/blog/2020/01/17/fda-approves-new-treatment-for-her2-positive-breast-cancer/
Certain patients with HER2-positive breast cancer have a new treatment option, following the FDA's approval of a new molecularly targeted ...
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23 HER2 Breast Cancer: Testing for Positive or Negative Status
https://www.cancercenter.com/cancer-types/breast-cancer/types/breast-cancer-molecular-types/her2
Standard treatment for most breast cancer starts with surgically removing the tumor, followed by radiation therapy, chemotherapy or a combination of both.
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24 Advances in the Treatment of Early-Stage HER2-Positive ...
https://www.hematologyandoncology.net/archives/august-2020/advances-in-the-treatment-of-early-stage-her2-positive-breast-cancer/
We review here key developments in neoadjuvant and adjuvant systemic therapy for early-stage HER2+ breast cancer and provide an overview of the current ...
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25 The Exciting New Field of HER2-Low Breast Cancer Treatment
https://www.mdpi.com/2072-6694/13/5/1015
So far, only patients with strong HER2 expression on their tumour can be treated with these benefitial drugs, like trastuzumab, ...
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26 Targeting HER2 for the Treatment of Breast Cancer
https://www.annualreviews.org/doi/10.1146/annurev-med-042513-015127
HER2 (ErbB2), a member of the HER family of tyrosine kinase receptors (HER1–4), is a major driver of tumor growth in 20% of breast cancers. Treatment with ...
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27 Neoadjuvant Treatment of HER2 Positive Early High-risk and ...
https://clinicaltrials.gov/ct2/show/NCT03595592
Neoadjuvant Treatment of HER2 Positive Early High-risk and Locally Advanced Breast Cancer (APTneo). The safety and scientific validity of this ...
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28 Treatments for HER2-Positive Breast Cancer - Verywell Health
https://www.verywellhealth.com/treatments-for-her2-positive-breast-cancer-4149987
A lumpectomy or mastectomy is typically recommended to remove the tumor in early-stage breast cancer. Radiation therapy may also be recommended ...
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29 Targeted therapeutic options and future perspectives for ...
https://www.nature.com/articles/s41392-019-0069-2
Several TKIs are in adjuvant clinical research for the treatment of HER2-positive early breast cancer (EBC). Various HER1/HER2 TKIs, ...
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30 PHESGO® (pertuzumab / trastuzumab / hyaluronidase-zzfx ...
https://www.phesgo.com/
Learn about PHESGO® (pertuzumab / trastuzumab / hyaluronidase-zzfx), a treatment option for HER2-positive breast cancer that's given in minutes.
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31 HER2 Positive Breast Cancer: What's New in Treatment and ...
https://www.youtube.com/watch?v=LRGU4N4PJs4
Dana-Farber Cancer Institute
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32 The changing treatment of metastatic her2‑positive breast ...
https://www.spandidos-publications.com/10.3892/ol.2021.12548
Human epidermal growth factor receptor 2 (HER2)‑overexpressing breast ... HER2‑targeting therapies have significantly changed treatment and ...
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33 Treatment of HER2-positive breast cancer - ScienceDirect.com
https://www.sciencedirect.com/science/article/pii/S0960977613003007
By 1998, antibody therapy targeting the HER2 pathway was shown to demonstrably improve progression-free and overall survival in metastatic disease, and in 2005 ...
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34 HER2-positive breast cancer, how far away from the cure?
https://cco.amegroups.com/article/view/10594/11236
Trastuzumab is the first humanized monoclonal anti-HER2 antibody approved by the US Food and Drug Administration (FDA) in 1998 for targeted therapy. In the last ...
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35 Risk-based decision-making in the treatment of HER2-positive ...
https://www.cancertreatmentreviews.com/article/S0305-7372(21)00077-3/fulltext
Treatment of HER2-positive early breast cancer (EBC) continues to evolve ... after neoadjuvant chemotherapy (NACT) plus anti-HER2 therapy [.
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36 HER2 (Breast Cancer) Testing: MedlinePlus Medical Test
https://medlineplus.gov/lab-tests/her2-breast-cancer-testing/
But treatments that specifically target HER2-positive breast cancer can be very effective. HER2 testing looks at a sample of tumor tissue to ...
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37 Cardiotoxicity and the Evolving Landscape of HER2-Targeted ...
https://www.acc.org/latest-in-cardiology/articles/2022/05/23/13/25/cardiotoxicity-and-the-evolving-landscape-of-her2-targeted-breast-cancer-treatment
Breast cancer survivors treated with cardiotoxic cancer therapies ... Recent efforts to tailor the treatment strategy for HER2-positive ...
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38 Trastuzumab Deruxtecan Expands Metastatic Breast Cancer ...
https://www.onclive.com/view/trastuzumab-deruxtecan-expands-metastatic-breast-cancer-treatment-landscape-across-her2-expressing-subtypes
Jane Lowe Meisel, MD, discussed the emergence of HER2-low as a new ... Breast Cancer Treatment Landscape Across HER2-Expressing Subtypes.
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39 HER-2 positive breast cancer | LBBC
https://www.lbbc.org/about-breast-cancer/types-breast-cancer/her2-positive
Treatments for HER2-positive breast cancer may include targeted therapies (medicines that specifically target the HER2 receptor), surgery, ...
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40 Anti-HER2 treatments for metastatic breast cancer
https://www.medicalnewstoday.com/articles/anti-her2-drugs-and-the-fight-against-mbc
Trastuzumab (Herceptin): This drug binds to the outer surface of HER2 proteins and inhibits their ability to receive growth signals.
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41 HER2 Positive Breast Cancer Treatment Information | Moffitt
https://moffitt.org/cancers/her2-positive-breast-cancer/
For early-stage HER2 positive breast cancer, a surgeon may resect the tumor as primary treatment. A lumpectomy or mastectomy may be used to remove the tumor.
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42 HER2 Positive Breast Cancer | Penn Medicine
https://www.pennmedicine.org/cancer/types-of-cancer/breast-cancer/types-of-breast-cancer/her2-positive-breast-cancer
Our Approach to HER2-Positive Treatment · Surgery for cancer, for the removal of either part (lumpectomy) or all (mastectomy) of the breast. · Breast ...
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43 Anti-HER2 therapy in metastatic breast cancer - Springer Link
https://link.springer.com/article/10.1007/s10555-022-10021-x
Mechanisms of action of anti-HER2 therapy by monoclonal antibodies (trastuzumab and pertuzumab), Fc-optimized antibody (margetuximab), ...
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44 New Guidelines on Treatment of HER2-Negative Breast ...
https://www.hoafredericksburg.com/new-guidelines-on-treatment-of-her2-negative-breast-cancer-aim-to-improve-patient-outcomes/
The American Society of Clinical Oncology (ASCO) recently released updated guidelines for the treatment of advanced HER2-negative breast cancer.
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45 Genentech Her2 Story
https://www.gene.com/stories/her2/
The HER2 Journey: The inside story of a breast cancer breakthrough, ... Instead of seeking additional treatment, Barbara was going to Mexico, off for a ...
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46 How we treat HER2-positive brain metastases - ESMO Open
https://www.esmoopen.com/article/S2059-7029(21)00218-0/fulltext
For patients with HER2-positive breast cancer who undergo breast conservation treatment and receive systemic therapy, the risk of brain ...
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47 HER2+ breast cancer: from no hope to good prognosis in 20 ...
https://perspectives.esmo.org/past-editions/all-articles/her2-breast-cancer-from-no-hope-to-good-prognosis-in-20-years
HER2 positive (HER2+) breast cancer is an outstanding example of what ... He was continually looking to make treatment better for patients.
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48 Exploring Targeted Therapy for HER2-Positive Metastatic ...
https://www.uspharmacist.com/article/exploring-targeted-therapy-for-her2positive-metastatic-breast-cancer
Exploring Targeted Therapy for HER2-Positive Metastatic Breast Cancer. Yvette C. Terrie, BS Pharm, RPh. Consultant Pharmacist/Medical Writer
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49 HER2 Targeted Therapy Now Open to Multiple Lines in Breast ...
https://www.targetedonc.com/view/treatment-options-for-her2-breast-cancer-open-to-multiple-lines-of-therapy-and-subgroups
Treatment Options for HER2+ Breast Cancer Open to Multiple Lines of Therapy and Subgroups · HER2-Targeted Agents Gain Indications in Metastatic ...
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50 HER2 - Breast Cancer Now
https://breastcancernow.org/information-support/facing-breast-cancer/diagnosed-breast-cancer/her2
All invasive breast cancers are tested for HER2 levels. This is done in a hospital ... Treatment for HER2 positive breast cancer. If your breast cancer is ...
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51 Evolving standards of care and new challenges in the ...
https://acsjournals.onlinelibrary.wiley.com/doi/10.3322/caac.21634
Specifically, patients with residual, invasive, HER2-positive BC after neoadjuvant chemotherapy and HER2-directed therapy had inferior oncologic ...
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52 Researchers Discover How to Overcome Treatment ...
https://www.insideprecisionmedicine.com/topics/oncology/breast-cancer/researchers-discover-how-to-overcome-treatment-resistance-in-her2-positive-breast-cancer/
Spanish researchers demonstrate the ability of a new therapy to overcome a treatment resistance mechanism in HER2 positive breast cancer.
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53 Enhertu approved in the US as the first HER2-directed therapy ...
https://www.astrazeneca.com/media-centre/press-releases/2022/enhertu-approved-in-the-us-for-her2-low-mbc.html
Enhertu approved in the US as the first HER2-directed therapy for ... for the treatment of patients with HER2-low metastatic breast cancer.
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54 HER2+ Breast Cancer Treatment | PERJETA® (pertuzumab)
https://www.perjeta.com/
Learn about PERJETA® in HER2-positive early and metastatic breast cancer. See Full Safety including Boxed Warnings for more information.
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55 How we treat HR-positive, HER2-negative early breast cancer
https://www.futuremedicine.com/doi/10.2217/fon-2021-0668
Hormone-based treatments for ER+/HER2- tumors deplete estrogen production, interrupt ER signalling, degrade ER, or alter ER-regulated signalling ...
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56 New Radionuclide Therapy Identified for HER2-Positive ...
https://www.snmmi.org/NewsPublications/NewsDetail.aspx?ItemNumber=38748
New Radionuclide Therapy Identified for HER2-Positive Breast Cancer Patients. September 28, 2021. Reston, VA—A promising radionuclide treatment may offer ...
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57 First-Line Efficacy of Anti-HER2 Treatments in Previously ...
https://www.karger.com/Article/FullText/516936
Background: Most patients with HER2-positive metastatic breast cancer (MBC) receive first-line treatment with anti-HER2 agents and have already received ...
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58 Groundbreaking New Treatment for Patients with HER2-Low ...
https://www.rockymountaincancercenters.com/blog/groundbreaking-new-treatment-for-patients-with-her2-low-breast-cancer
HER2-positive breast cancers are likely to respond well to a targeted therapy called trastuzumab, with a brand and name of Herceptin (among others). Other ...
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59 The Conundrum of Adjuvant HER2 Treatment Options - Frontiers
https://www.frontiersin.org/articles/10.3389/fonc.2018.00177/full
Abstract: Improving outcomes in HER2 overexpressing breast cancer has ... Role of Dual HER2 blockade in the adjuvant treatment APHINITY was ...
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60 Breast Cancer and HER2 - Medscape Reference
https://emedicine.medscape.com/article/1689966-overview
Most experts do not recommend HER2-targeted therapy if the HER2 test result is negative and ... Treatment of HER2-positive breast cancer.
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61 Appropriate Treatment for Patients with Stage I (T1c) – III HER2
https://qpp.cms.gov/docs/QPP_quality_measure_specifications/CQM-Measures/2022_Measure_450_MIPSCQM.pdf
DESCRIPTION: Percentage of female patients aged 18 to 70 with stage I (T1c) – III HER2 positive breast cancer for whom appropriate treatment is initiated ...
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62 With Perjeta, the Cost of HER2 Breast Cancer Therapy Goes Up
https://www.practiceupdate.com/content/with-perjeta-the-cost-of-her2-breast-cancer-therapy-goes-up/12388
Labeling for Perjeta includes a section on HER2 testing to identify the appropriate patients for treatment. FDA approved Denmark-based ...
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63 HER2-Low Classification Is a 'Big Leap Forward' for Breast ...
https://www.curetoday.com/view/her2-low-classification-is-a-big-leap-forward-for-breast-cancer-treatment
It has been almost 25 years since the approval of Herceptin (trastuzumab), a groundbreaking therapy that targeted the human epidermal growth ...
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64 Perioperative HER2 targeted treatment in early stage HER2 ...
https://journals.sagepub.com/doi/full/10.1177/17588359221106564
In the future, tailored treatments such as no adjuvant therapy, various HER2-directed therapies alone with chemotherapy, combinations of various ...
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65 FDA Approves First Drug To Treat HER2-Low Breast Cancer
https://www.henryford.com/blog/2022/10/her2-breast-cancer-treatments
Breakthroughs In Treating HER2 Breast Cancer. “Enhertu combines monoclonal antibody therapy with chemotherapy,” says Dr. Ali. “Here's how it ...
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66 6 versus 12 months of adjuvant trastuzumab for HER2-positive ...
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)30650-6/fulltext
We have shown that 6-month trastuzumab treatment is non-inferior to 12-month treatment in patients with HER2-positive early breast cancer, with ...
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67 HER2-Positive Breast Cancer Treatments Are Rapidly Evolving
https://journals.lww.com/oncology-times/fulltext/2022/05200/her2_positive_breast_cancer_treatments_are_rapidly.8.aspx
Within this class are two drugs that have since been approved for HER2-positive breast cancer, including trastuzumab emtansine (T-DM1) and ...
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68 Therapeutic Options for HER2-Positive, Early-Stage Breast ...
https://www.cancertherapyadvisor.com/howtotreat/breast-cancer-her2-target-therapy/
Those women with larger or more aggressive HER2-positive cancers may undergo neoadjuvant treatment with chemotherapy plus trastuzumab in order ...
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69 HER2 Secondary Breast Cancer: All of the treatments ...
https://owise.uk/her2-secondary-breast-cancer-treatments/
In our third blog with Make2ndsCount, we'll be looking in depth at current and future treatments for HER2 secondary breast cancer patients.
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70 More Metastatic Breast Cancer Patients May Qualify for an ...
https://baptisthealth.net/baptist-health-news/more-metastatic-breast-cancer-patients-may-qualify-for-an-fda-approved-infusion-treatment/
The groundbreaking new treatment by drugmaker AstraZeneca is showing ... “This is the first approved therapy for HER2-low breast cancer and ...
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71 Treatment of HER2-overexpressing breast cancer
https://www.annalsofoncology.org/article/S0923-7534(19)39724-8/fulltext
Novel strategies against HER2 include HER tyrosine kinase inhibitors, HSP90 inhibitors and antibody–chemotherapy conjugates. This latter approach is exemplified ...
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72 Injectable Treatment for HER2 Positive Breast Cancer
https://www.herceptinhylecta.com/patient.html
Access details about Herceptin Hylecta™ (trastuzumab and hyaluronidase‐oysk), a subcutaneous injection for your HER2 positive breast cancer treatment.
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73 New treatment outperforms chemo in HER2-low breast cancer
https://www.mdedge.com/hematology-oncology/article/255204/asco-breast-cancer/new-treatment-outperforms-chemo-her2-low
The therapy doubled progression-free survival versus chemotherapy in patients with hormone receptor positive (HR+) and low levels of HER2.
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74 Personalizing Treatment of Early HER2-Positive Breast Cancer
https://ascopost.com/issues/july-10-2021/personalizing-treatment-of-early-her2-positive-breast-cancer/
“Dual HER2 targeting is a way to escalate treatment in a poor-risk patient, and the results of neoadjuvant therapy are actionable.” — Debu ...
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75 Baseline Characteristics, Treatment Patterns, and Outcomes ...
https://aacrjournals.org/clincancerres/article/26/5/1105/83050/Baseline-Characteristics-Treatment-Patterns-and
We report treatments and outcomes in a contemporary patient population with HER2-positive metastatic breast cancer (MBC) by hormone receptor (HR) status from ...
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76 New HER2 assay may be needed to guide breast cancer ...
https://www.healio.com/news/hematology-oncology/20220415/new-her2-assay-may-be-needed-to-guide-breast-cancer-treatment-with-trastuzumab-deruxtecan
The use of current standard HER2 assays as diagnostic tests may result in misassignment of patients for treatment of breast cancer with ...
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77 What You Should Know About the New Treatment for HER2 ...
https://www.inspirahealthnetwork.org/news/what-you-should-know-about-new-treatment-her2-low-breast-cancer
The FDA recently announced its approval for Enhertu, a new therapy for HER2-low breast cancer. As the first treatment specifically tailored ...
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78 Systemic Therapy Options for Treating HR+/HER2– Metastatic ...
https://www.pharmacytimes.com/view/systemic-therapy-options-for-treating-hrher2-metastatic-breast-cancer
The initial treatment of HR+/HER2— metastatic breast cancer is dictated by the National Comprehensive Cancer Network (NCCN) Clinical ...
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79 Targeted therapy | Breast Cancer Network Australia
https://www.bcna.org.au/understanding-breast-cancer/treatment/targeted-therapy/
Herceptin (trastuzumab) is the best known of the targeted therapies and is used to treat HER2-positive breast cancer. Herceptin does not work for everyone.
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80 Breast Cancer Drug Trial Results in 'Unheard-Of' Survival
https://www.nytimes.com/2022/06/07/health/enhertu-breast-cancer-chemotherapy.html
But a treatment with a drug that targeted cancer cells with laserlike ... Drugs that block HER2 have been stunningly effective in treating ...
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81 HER2-Positive Breast Cancer Treatment | PHESGO ...
https://www.phesgo-hcp.com/
Learn about PHESGO® (pertuzumab / trastuzumab / hyaluronidase-zzfx), a subcutaneous injection for HER2-positive breast cancer. See Full Safety and Boxed ...
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82 CLO22-090: Patient Characteristics, Treatment Patterns, and ...
https://jnccn.org/view/journals/jnccn/20/3.5/article-pCLO22-090.xml
CLO22-090: Patient Characteristics, Treatment Patterns, and Clinical Outcomes of Patients With Advanced HER2-Low Breast Cancer.
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83 Updates in the Treatment of HER2+ and HER2-Low Breast ...
https://cancer.uillinois.edu/episode-1-updates-in-the-treatment-of-her2-and-her2-low-breast-cancer/?utm_source=rss&utm_medium=rss&utm_campaign=episode-1-updates-in-the-treatment-of-her2-and-her2-low-breast-cancer
University of Illinois Cancer Center
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84 A potentially more effective treatment for HER2 mutant ...
https://www.bcm.edu/news/a-potentially-more-effective-treatment-for-her2-mutant-metastatic-breast-cancer
These findings support conducting future clinical trials to assess the value of poziotinib to treat HER2-mutant driven metastatic breast ...
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85 HER2 Positive Metastatic Breast Cancer Research Update
https://metastatictrialtalk.org/research-news/her2-positive-breast-cancer-research-update/
The treatment landscape for HER2 positive metastatic breast cancer has been rapidly evolving. Since February, the FDA has approved three new ...
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86 Treatment Beyond Second-line Therapy in HER2+ mBC
https://www.ajmc.com/view/treatment-beyond-second-line-therapy-in-her2-mbc
Exploring current advances in treatment options beyond the second-line setting for progressive HER2-positive metastatic breast cancer.
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87 HER2-Positive Metastatic Breast Cancer: New Options, New ...
https://www.oncologynurseadvisor.com/home/headlines/conference-coverage/ona-summit-2022/breast-cancer-her2-positive-metastatic-new-options-hope-treatment-risk/
Future directions in therapy, Kuiper highlighted, include HER2-targeting treatments in clinical trials, next generation sequencing, and ...
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88 Targeted Therapy - National Breast Cancer Foundation
https://www.nationalbreastcancer.org/breast-cancer-targeted-therapy
Herceptin: Targeting HER2-Positive Receptors. Monoclonal antibody drugs such as Herceptin (also known as Trastuzumab) target HER2-positive tumors. If cancer ...
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89 AstraZeneca aims to redefine breast cancer ... - AstraZeneca US
https://www.astrazeneca-us.com/media/press-releases/2022/astrazeneca-aims-to-redefine-breast-cancer-care-with-new-data-across-the-treatment-spectrum-at-sabcs-2022-11232022.html
Two late-breaking presentations from the DESTINY-Breast clinical program will highlight the efficacy of ENHERTU treatment in patients with HER2- ...
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90 Treatment Landscape for Patients with HER2-Positive ...
https://www.dovepress.com/treatment-landscape-for-patients-with-her2-positive-metastatic-breast--peer-reviewed-fulltext-article-CMAR
Treatment Landscape for Patients with HER2-Positive Metastatic Breast Cancer: A Review on Emerging Treatment Options.
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91 Merck Announces Phase 3 KEYNOTE-859 Trial Met Primary ...
https://www.merck.com/news/merck-announces-phase-3-keynote-859-trial-met-primary-endpoint-of-overall-survival-in-patients-with-her2-negative-gastric-or-gastroesophageal-junction-gej-adenocarcinoma/
... in combination with chemotherapy for the first-line treatment of patients with human epidermal growth factor receptor 2 (HER2)-negative ...
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92 HER2 Positive Breast Cancer
https://www.breastcancercourse.org/her2-positive-cancer-3-2/
Treated with Chemo and “Targeted Therapy”. HER2 Receptor Positive (HER2+) tumors are incredibly responsive to chemotherapy when paired with new breakthrough ...
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93 AstraZeneca Aims to Redefine Breast Cancer ... - Business Wire
https://www.businesswire.com/news/home/20221121005994/en/AstraZeneca-Aims-to-Redefine-Breast-Cancer-Care-With-New-Data-Across-the-Treatment-Spectrum-At-SABCS-2022
Trastuzumab deruxtecan for the treatment of patients with HER2-positive breast cancer with brain and/or leptomeningeal metastases: A ...
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94 Battling Stage 4 Breast Cancer for 4 Years - UConn Today
https://today.uconn.edu/2022/11/battling-stage-4-breast-cancer-for-4-years-i-have-cancer-but-cancer-does-not-have-me/
In 2018, she was diagnosed with Invasive Ductal Carcinoma Her2 positive, ... Anti-estrogen pills are of no value in treating this cancer.
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95 Adding Perjeta to the Treatment of HER2-Positive Tumors ...
https://www.breastlink.com/blog/perjeta/
This trial led to the FDA's approval of pertuzumab in combination with herceptin and chemotherapy in 2012 for treatment of metastatic, HER2- ...
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96 HER2+ Breast Cancer - Oncology Specialists of Charlotte
https://oncologycharlotte.com/her2-breast-cancer/
For women with HER2+ breast cancer, Herceptin (generic name: Trastuzumab) can be used as a form of treatment. The HER2 gene is present in ...
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97 Herceptin—a targeted antibody therapy for breast cancer
https://laskerfoundation.org/winners/herceptin-a-targeted-antibody-therapy-for-breast-cancer/
They named it HER2—human EGF receptor 2—because of this similarity. Its sequence and location on the chromosome suggested that it might be the ...
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