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Google Keyword Rankings for : what does ligase do
1
DNA ligase - Wikipedia
https://en.wikipedia.org/wiki/DNA_ligase
In biochemistry, a ligase is an enzyme that can catalyze the joining (ligation) of two large molecules by forming a new chemical bond. This is typically via ...
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https://en.wikipedia.org/wiki/DNA_ligase
In biochemistry, a ligase is an enzyme that can catalyze the joining (ligation) of two large molecules by forming a new chemical bond. This is typically via ...
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2
Ligase - Definition and Examples - Biology Online Dictionary
https://www.biologyonline.com/dictionary/ligase
Biology/Biochemistry definition: Ligase is an enzyme that catalyzes the binding of two molecules. An example is a DNA ligase that links two ...
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https://www.biologyonline.com/dictionary/ligase
Biology/Biochemistry definition: Ligase is an enzyme that catalyzes the binding of two molecules. An example is a DNA ligase that links two ...
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3
3. What is DNA Ligase? - LabXchange
https://www.labxchange.org/library/pathway/lx-pathway:eb23624c-22b2-4862-95ca-4c5123008519/items/lx-pb:eb23624c-22b2-4862-95ca-4c5123008519:html:e28ba1c1
DNA ligase works by catalyzing the formation of a phosphodiester bond between nucleotides on one strand of a double stranded DNA molecule. DNA ...
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https://www.labxchange.org/library/pathway/lx-pathway:eb23624c-22b2-4862-95ca-4c5123008519/items/lx-pb:eb23624c-22b2-4862-95ca-4c5123008519:html:e28ba1c1
DNA ligase works by catalyzing the formation of a phosphodiester bond between nucleotides on one strand of a double stranded DNA molecule. DNA ...
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4
DNA Ligase - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/neuroscience/dna-ligase
Here, the term will be used for DNA-ligases, which play a central role in DNA replication, recombination, and repair. These ligases are used to close ...
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https://www.sciencedirect.com/topics/neuroscience/dna-ligase
Here, the term will be used for DNA-ligases, which play a central role in DNA replication, recombination, and repair. These ligases are used to close ...
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5
DNA Ligase Function & Role | Ligase in DNA Replication
https://study.com/academy/lesson/dna-ligase-definition-role-quiz.html
The role of DNA ligase is to glue those DNA fragments together to form 2 new daughter DNA strands. It does so by facilitating the formation of a ...
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https://study.com/academy/lesson/dna-ligase-definition-role-quiz.html
The role of DNA ligase is to glue those DNA fragments together to form 2 new daughter DNA strands. It does so by facilitating the formation of a ...
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6
ligase | biochemistry | Britannica
https://www.britannica.com/science/ligase
A ligase catalyzing the formation of a carbon-oxygen bond between an amino acid and transfer RNA is called amino acid–RNA ligase.
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https://www.britannica.com/science/ligase
A ligase catalyzing the formation of a carbon-oxygen bond between an amino acid and transfer RNA is called amino acid–RNA ligase.
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7
Structure and function of the DNA ligases encoded by ... - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881560/
DNA ligases play an essential role in maintaining genomic integrity by joining breaks in the phosphodiester backbone of DNA that occur during ...
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881560/
DNA ligases play an essential role in maintaining genomic integrity by joining breaks in the phosphodiester backbone of DNA that occur during ...
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8
Overview of T4 DNA Ligase: What it is, how it works, reactions ...
https://goldbio.com/articles/article/overview-of-T4-DNA-ligase
T4 DNA ligase is an enzyme that fixes broken DNA and seals it – similar to super glue. This particular DNA ligase was isolated from bacteriophage T4.
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https://goldbio.com/articles/article/overview-of-T4-DNA-ligase
T4 DNA ligase is an enzyme that fixes broken DNA and seals it – similar to super glue. This particular DNA ligase was isolated from bacteriophage T4.
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9
DNA Ligation: 6 easy tips to improve your reactions
https://bitesizebio.com/10279/how-dna-ligation-works/
The ATP in the ligase buffer is essential for the DNA ligation reaction but can be broken down by repeated freeze-thaw cycles. To avoid this, ...
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https://bitesizebio.com/10279/how-dna-ligation-works/
The ATP in the ligase buffer is essential for the DNA ligation reaction but can be broken down by repeated freeze-thaw cycles. To avoid this, ...
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10
Protocol - How to Ligate Plasmid DNA - Addgene
https://www.addgene.org/protocols/dna-ligation/
This is accomplished by covalently connecting the sugar backbone of the two DNA fragments. This reaction, called ligation, is performed by the T4 DNA ligase ...
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https://www.addgene.org/protocols/dna-ligation/
This is accomplished by covalently connecting the sugar backbone of the two DNA fragments. This reaction, called ligation, is performed by the T4 DNA ligase ...
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11
ATP-dependent DNA ligases | Genome Biology | Full Text
https://genomebiology.biomedcentral.com/articles/10.1186/gb-2002-3-4-reviews3005
DNA ligase I is required for the ligation of Okazaki fragments during lagging-strand DNA synthesis, as well as for several DNA-repair pathways; ...
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https://genomebiology.biomedcentral.com/articles/10.1186/gb-2002-3-4-reviews3005
DNA ligase I is required for the ligation of Okazaki fragments during lagging-strand DNA synthesis, as well as for several DNA-repair pathways; ...
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12
Dynamics of phosphodiester synthesis by DNA ligase - PNAS
https://www.pnas.org/doi/full/10.1073/pnas.0800113105
Ligases are essential actors in DNA replication, recombination, and repair by virtue of their ability to seal breaks in the phosphodiester backbone.
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https://www.pnas.org/doi/full/10.1073/pnas.0800113105
Ligases are essential actors in DNA replication, recombination, and repair by virtue of their ability to seal breaks in the phosphodiester backbone.
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13
Molecule of the Month: DNA Ligase - PDB-101
https://pdb101.rcsb.org/motm/55
With these two types of enzymes, researchers can cut and paste DNA strands at will, designing new genes and new genomes. Restriction enzymes are like scissors, ...
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https://pdb101.rcsb.org/motm/55
With these two types of enzymes, researchers can cut and paste DNA strands at will, designing new genes and new genomes. Restriction enzymes are like scissors, ...
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14
DNA Ligation - GenScript
https://www.genscript.com/what-is-dna-ligation.html
DNA Ligation is the joining of 2 DNA molecules by the enzyme, DNA ligase. DNA ligase catalyzes the formation of two covalent phosphodiester bonds between ...
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https://www.genscript.com/what-is-dna-ligation.html
DNA Ligation is the joining of 2 DNA molecules by the enzyme, DNA ligase. DNA ligase catalyzes the formation of two covalent phosphodiester bonds between ...
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15
Optimize Your DNA Ligation with 7 Must-Have Tips - US
https://www.thermofisher.com/us/en/home/brands/thermo-scientific/molecular-biology/molecular-biology-learning-center/molecular-biology-resource-library/spotlight-articles/optimize-dna-ligase.html
The unique T4 DNA Ligase buffer optimizes ligation, which can be performed in 5 minutes (1). Single-stranded nucleic acids are not substrates for this ...
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https://www.thermofisher.com/us/en/home/brands/thermo-scientific/molecular-biology/molecular-biology-learning-center/molecular-biology-resource-library/spotlight-articles/optimize-dna-ligase.html
The unique T4 DNA Ligase buffer optimizes ligation, which can be performed in 5 minutes (1). Single-stranded nucleic acids are not substrates for this ...
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16
DNA sequencing part 2: ligases and PCR | Ars Technica
https://arstechnica.com/science/2009/11/dna-sequencing-part-2-ligases-and-pcr/
The reaction performed by DNA ligase simply links the phosphate to a neighboring sugar, establishing the normal DNA backbone. It can repair a ...
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https://arstechnica.com/science/2009/11/dna-sequencing-part-2-ligases-and-pcr/
The reaction performed by DNA ligase simply links the phosphate to a neighboring sugar, establishing the normal DNA backbone. It can repair a ...
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17
T4 DNA Ligase - Takara Bio
https://www.takarabio.com/products/cloning/ligation-enzymes/t4-dna-ligase
T4 DNA Ligase is a ligation enzyme that can be used to join DNA fragments by catalyzing the formation of phosphodiester bonds between juxtaposed 5' ...
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https://www.takarabio.com/products/cloning/ligation-enzymes/t4-dna-ligase
T4 DNA Ligase is a ligation enzyme that can be used to join DNA fragments by catalyzing the formation of phosphodiester bonds between juxtaposed 5' ...
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18
Ligation ( Using T4 DNA Ligase) (Theory) : Molecular Biology ...
https://vlab.amrita.edu/?sub=3&brch=186&sim=781&cnt=1
DNA fragments with either sticky ends or blunt ends can be inserted into vector DNA with the aid of DNA ligases. During normal DNA replication, DNA ligase ...
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https://vlab.amrita.edu/?sub=3&brch=186&sim=781&cnt=1
DNA fragments with either sticky ends or blunt ends can be inserted into vector DNA with the aid of DNA ligases. During normal DNA replication, DNA ligase ...
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19
From Structure-Function Analyses to Protein Engineering for ...
https://www.hindawi.com/journals/archaea/2015/267570/
DNA ligases are broadly utilized in molecular biology research fields, such as genetic engineering and DNA sequencing technologies. Here we review the ...
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https://www.hindawi.com/journals/archaea/2015/267570/
DNA ligases are broadly utilized in molecular biology research fields, such as genetic engineering and DNA sequencing technologies. Here we review the ...
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20
DNA ligation - Science Learning Hub
https://www.sciencelearn.org.nz/resources/2034-dna-ligation
... ligases are used to join fragments of DNA together. Only DNA fragments that have matching, complementary ends can be joined by ligation.
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https://www.sciencelearn.org.nz/resources/2034-dna-ligation
... ligases are used to join fragments of DNA together. Only DNA fragments that have matching, complementary ends can be joined by ligation.
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21
DNA Ligase, T4 - Worthington Enzyme Manual
https://www.worthington-biochem.com/products/dna-ligase-t4/manual
T4 DNA ligase is an ATP-dependent ligase that catalyzes a joining reaction between DNA molecules. By joining the 3'-hydroxy and 5'-phosphate termini to form ...
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https://www.worthington-biochem.com/products/dna-ligase-t4/manual
T4 DNA ligase is an ATP-dependent ligase that catalyzes a joining reaction between DNA molecules. By joining the 3'-hydroxy and 5'-phosphate termini to form ...
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22
Structural intermediates of a DNA–ligase complex illuminate ...
https://academic.oup.com/nar/article/47/14/7147/5532291
DNA ligases are modular enzymes comprising at a minimum, a two-domain catalytic core with the active-site bearing adenylation (AD) domain ...
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https://academic.oup.com/nar/article/47/14/7147/5532291
DNA ligases are modular enzymes comprising at a minimum, a two-domain catalytic core with the active-site bearing adenylation (AD) domain ...
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23
DNA Ligation Protocol - Sigma-Aldrich
https://www.sigmaaldrich.com/US/en/technical-documents/protocol/genomics/cloning-and-expression/dna-ligation-kit
P4978) will prevent self-ligation. Dephosphorylated vector will ligate only to a DNA insert possessing 5'-phosphate moieties, forming two phosphodiester bonds.
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https://www.sigmaaldrich.com/US/en/technical-documents/protocol/genomics/cloning-and-expression/dna-ligation-kit
P4978) will prevent self-ligation. Dephosphorylated vector will ligate only to a DNA insert possessing 5'-phosphate moieties, forming two phosphodiester bonds.
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24
Ligation - MyBioSource Learning Center
https://www.mybiosource.com/learn/testing-procedures/ligation/
Ligation can be described as the process of joining two nucleic acid fragments catalyzed by an enzyme. It finds its application in molecular cloning and ...
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https://www.mybiosource.com/learn/testing-procedures/ligation/
Ligation can be described as the process of joining two nucleic acid fragments catalyzed by an enzyme. It finds its application in molecular cloning and ...
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25
Taq DNA Ligase
https://www.protean.bio/en/article/taq-dna-ligase
The Taq DNA Ligase is NAD+ dependent thermostable DNA ligase from the thermophilic bacterium Thermus aquaticus. The function of this enzyme ...
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https://www.protean.bio/en/article/taq-dna-ligase
The Taq DNA Ligase is NAD+ dependent thermostable DNA ligase from the thermophilic bacterium Thermus aquaticus. The function of this enzyme ...
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26
DNA Ligase-Mediated Translation of DNA Into Densely ...
https://pubs.acs.org/doi/10.1021/ja311331m
This polymerization proceeds sequence specifically along a DNA template and can generate polymers of at least 50 building blocks (150 ...
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https://pubs.acs.org/doi/10.1021/ja311331m
This polymerization proceeds sequence specifically along a DNA template and can generate polymers of at least 50 building blocks (150 ...
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27
Tips for blunt-end DNA cloning and ligation - IDT
https://www.idtdna.com/pages/education/decoded/article/cloning-strategies-part-3-blunt-end-cloning
The vector can be prepared by digestion if the multiple cloning site (MCS) contains a recognition site for a restriction enzyme that produces ...
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https://www.idtdna.com/pages/education/decoded/article/cloning-strategies-part-3-blunt-end-cloning
The vector can be prepared by digestion if the multiple cloning site (MCS) contains a recognition site for a restriction enzyme that produces ...
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28
Does DNA ligase have any role to play in replication on ...
https://biology.stackexchange.com/questions/105304/does-dna-ligase-have-any-role-to-play-in-replication-on-leading-strand
The work of DNA ligase is to form "phospho-ester bond" or "phospho-diester bond"(bond joining phosphate of one nucleotide with OH of another ...
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https://biology.stackexchange.com/questions/105304/does-dna-ligase-have-any-role-to-play-in-replication-on-leading-strand
The work of DNA ligase is to form "phospho-ester bond" or "phospho-diester bond"(bond joining phosphate of one nucleotide with OH of another ...
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29
Taq DNA Ligase #M0208 - NEB UK
https://www.neb.uk.com/products/neb-catalogue/dna-modifying-enzymes-(cloning)/lt;em-gt;taq-lt;-em-gt;-dna-ligase
DNA Ligase is a thermostable ligase that catalyzes the formation of a phosphodiester bond between the 5´-phosphate and the 3´-hydroxyl of two adjacent DNA ...
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https://www.neb.uk.com/products/neb-catalogue/dna-modifying-enzymes-(cloning)/lt;em-gt;taq-lt;-em-gt;-dna-ligase
DNA Ligase is a thermostable ligase that catalyzes the formation of a phosphodiester bond between the 5´-phosphate and the 3´-hydroxyl of two adjacent DNA ...
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30
MAMMALIAN DNA LIGASES - Annual Reviews
https://www.annualreviews.org/doi/pdf/10.1146/annurev.bi.61.070192.001343
One of these is bacteriophage T4 RNA ligase, the product of T4 gene 63, which can catalyze the ligation of single-stranded ribo-oligonucleotides and deoxyribo.
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https://www.annualreviews.org/doi/pdf/10.1146/annurev.bi.61.070192.001343
One of these is bacteriophage T4 RNA ligase, the product of T4 gene 63, which can catalyze the ligation of single-stranded ribo-oligonucleotides and deoxyribo.
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31
DNA Replication (HL) - BioNinja
http://ib.bioninja.com.au/higher-level/topic-7-nucleic-acids/71-dna-structure-and-replic/dna-replication-hl.html
DNA Replication (HL) · DNA ligase joins the Okazaki fragments together to form a continuous strand · It does this by covalently joining the sugar-phosphate ...
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http://ib.bioninja.com.au/higher-level/topic-7-nucleic-acids/71-dna-structure-and-replic/dna-replication-hl.html
DNA Replication (HL) · DNA ligase joins the Okazaki fragments together to form a continuous strand · It does this by covalently joining the sugar-phosphate ...
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32
What is the Difference Between DNA Ligase and DNA ...
https://pediaa.com/what-is-the-difference-between-dna-ligase-and-dna-polymerase/
DNA ligase is the enzyme that plays an essential role in joining mainly single-strand breaks in the double-stranded DNA during DNA replication, ...
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https://pediaa.com/what-is-the-difference-between-dna-ligase-and-dna-polymerase/
DNA ligase is the enzyme that plays an essential role in joining mainly single-strand breaks in the double-stranded DNA during DNA replication, ...
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33
Cutting and Pasting DNA- Restriction Digests and DNA Ligation
https://bio.libretexts.org/Bookshelves/Genetics/Book%3A_Online_Open_Genetics_(Nickle_and_Barrette-Ng)/08%3A_Techniques_of_Molecular_Genetics/8.04%3A_Cutting_and_Pasting_DNA-_Restriction_Digests_and_DNA_Ligation
Note: sticky-ended molecules with non-complementary sequences will not ligate together with DNA ligase. Ligation is therefore central to the ...
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https://bio.libretexts.org/Bookshelves/Genetics/Book%3A_Online_Open_Genetics_(Nickle_and_Barrette-Ng)/08%3A_Techniques_of_Molecular_Genetics/8.04%3A_Cutting_and_Pasting_DNA-_Restriction_Digests_and_DNA_Ligation
Note: sticky-ended molecules with non-complementary sequences will not ligate together with DNA ligase. Ligation is therefore central to the ...
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34
High School Biology : Understanding Replication Proteins
https://www.varsitytutors.com/high_school_biology-help/understanding-replication-proteins
DNA ligase is the protein responsible for linking, or ligating, Okazaki fragments together in order to form a single complete DNA strand. This action only ...
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https://www.varsitytutors.com/high_school_biology-help/understanding-replication-proteins
DNA ligase is the protein responsible for linking, or ligating, Okazaki fragments together in order to form a single complete DNA strand. This action only ...
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35
XRCC4:DNA ligase IV can ligate incompatible ... - EMBO Press
https://www.embopress.org/doi/10.1038/sj.emboj.7601559
XRCC4 and DNA ligase IV form a complex that is essential for the repair of all double-strand DNA breaks by the nonhomologous DNA end joining pathway in ...
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https://www.embopress.org/doi/10.1038/sj.emboj.7601559
XRCC4 and DNA ligase IV form a complex that is essential for the repair of all double-strand DNA breaks by the nonhomologous DNA end joining pathway in ...
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36
DNA ligase | Encyclopedia.com
https://www.encyclopedia.com/science/dictionaries-thesauruses-pictures-and-press-releases/dna-ligase
DNA ligase is also used in recombinant DNA technology (see genetic engineering) as it ensures that the foreign DNA (e.g. the complementary DNA used in gene ...
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https://www.encyclopedia.com/science/dictionaries-thesauruses-pictures-and-press-releases/dna-ligase
DNA ligase is also used in recombinant DNA technology (see genetic engineering) as it ensures that the foreign DNA (e.g. the complementary DNA used in gene ...
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37
Difference Between DNA Ligase and DNA Polymerase
https://www.differencebetween.com/difference-between-dna-ligase-and-vs-dna-polymerase/
DNA ligase is an enzyme which catalyzes the formation of phosphodiester bond between 3' – OH and 5'- PO4 groups of nucleotides and facilitates ...
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https://www.differencebetween.com/difference-between-dna-ligase-and-vs-dna-polymerase/
DNA ligase is an enzyme which catalyzes the formation of phosphodiester bond between 3' – OH and 5'- PO4 groups of nucleotides and facilitates ...
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38
DNA Ligase III as a Candidate Component of Backup ...
https://aacrjournals.org/cancerres/article/65/10/4020/517940/DNA-Ligase-III-as-a-Candidate-Component-of-Backup
An in vivo plasmid assay shows that DNA ligase IV–deficient mouse embryo fibroblasts retain significant DNA end joining activity that can be ...
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https://aacrjournals.org/cancerres/article/65/10/4020/517940/DNA-Ligase-III-as-a-Candidate-Component-of-Backup
An in vivo plasmid assay shows that DNA ligase IV–deficient mouse embryo fibroblasts retain significant DNA end joining activity that can be ...
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39
119 questions with answers in DNA LIGASE | Science topic
https://www.researchgate.net/topic/DNA-Ligase
How long did you incubate the ligation reaction? I know some kits claim 5 minutes, but longer is usually better. Ligase & competent cells are both heat- ...
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https://www.researchgate.net/topic/DNA-Ligase
How long did you incubate the ligation reaction? I know some kits claim 5 minutes, but longer is usually better. Ligase & competent cells are both heat- ...
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40
Ligate Sticky Ends via DNA Ligation - SciGine
https://scigine.com/blog/ligate-sticky-ends-via-dna-ligation/
DNA Ligation is used to combine DNA in gene cloning. Ligate your target gene into a shuttle vector via sticky ends with this DNA Ligation ...
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https://scigine.com/blog/ligate-sticky-ends-via-dna-ligation/
DNA Ligation is used to combine DNA in gene cloning. Ligate your target gene into a shuttle vector via sticky ends with this DNA Ligation ...
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41
Information on EC 6.5.1.1 - DNA ligase (ATP)
https://www.brenda-enzymes.org/enzyme.php?ecno=6.5.1.1
The enzyme catalyses the ligation of DNA strands with 3'-hydroxyl and 5'-phosphate termini, forming a phosphodiester and sealing certain types of ...
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https://www.brenda-enzymes.org/enzyme.php?ecno=6.5.1.1
The enzyme catalyses the ligation of DNA strands with 3'-hydroxyl and 5'-phosphate termini, forming a phosphodiester and sealing certain types of ...
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42
Frequently Asked Questions - T4 DNA Ligase [Standard conc.
https://www.affymetrix.com/support/technical/usb/faq/USB_T4_DNA_Ligase_FAQ.pdf
Can ligation conditions affect transformation efficiency? Yes, some factors are listed below: ▫. If the reaction buffer contains PEG and the ligation was ...
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https://www.affymetrix.com/support/technical/usb/faq/USB_T4_DNA_Ligase_FAQ.pdf
Can ligation conditions affect transformation efficiency? Yes, some factors are listed below: ▫. If the reaction buffer contains PEG and the ligation was ...
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43
What Is DNA Ligase? And How T4 DNA Ligase Works?
https://geneticeducation.co.in/what-is-dna-ligase-and-how-t4-dna-ligase-works/
In a simple language, we can the ligase is a natural sealant just like a glue that ties two single-stranded ends or two double strands of ...
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https://geneticeducation.co.in/what-is-dna-ligase-and-how-t4-dna-ligase-works/
In a simple language, we can the ligase is a natural sealant just like a glue that ties two single-stranded ends or two double strands of ...
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44
DNA ligase - The School of Biomedical Sciences Wiki
https://teaching.ncl.ac.uk/bms/wiki/index.php/DNA_ligase
DNA ligase is an enzyme that anneals DNA strands together. It forms a phosphodiester bond between the complementary bases on two separate ...
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https://teaching.ncl.ac.uk/bms/wiki/index.php/DNA_ligase
DNA ligase is an enzyme that anneals DNA strands together. It forms a phosphodiester bond between the complementary bases on two separate ...
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45
DNA Replication
https://www.ndsu.edu/pubweb/~mcclean/plsc431/eukarychrom/eukaryo2.htm
Primase - The requirement for a free 3' hydroxyl group is fulfilled by the RNA primers that are synthesized at the initiation sites by these enzymes. DNA Ligase ...
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https://www.ndsu.edu/pubweb/~mcclean/plsc431/eukarychrom/eukaryo2.htm
Primase - The requirement for a free 3' hydroxyl group is fulfilled by the RNA primers that are synthesized at the initiation sites by these enzymes. DNA Ligase ...
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46
What is the role of the enzyme ligase in replication? - Socratic
https://socratic.org/questions/what-is-the-role-of-the-enzyme-ligase-in-replication
Ligase fills in missing nucleotides on the lagging stand of DNA during replication. Explanation: Since the leading stand in DNA is being ...
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https://socratic.org/questions/what-is-the-role-of-the-enzyme-ligase-in-replication
Ligase fills in missing nucleotides on the lagging stand of DNA during replication. Explanation: Since the leading stand in DNA is being ...
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47
CircLigase ssDNA Ligase - LGC, Biosearch Technologies
https://shop.biosearchtech.com/molecular-biology-enzymes/dna-and-rna-modifying-enzymes/dna-and-rna-ligases/circligase-ssdna-ligase/p/NXGENZ-002
The enzyme is therefore useful for making circular ssDNA molecules from linear ssDNA. Circular ssDNA molecules can be used as substrates for rolling-circle ...
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https://shop.biosearchtech.com/molecular-biology-enzymes/dna-and-rna-modifying-enzymes/dna-and-rna-ligases/circligase-ssdna-ligase/p/NXGENZ-002
The enzyme is therefore useful for making circular ssDNA molecules from linear ssDNA. Circular ssDNA molecules can be used as substrates for rolling-circle ...
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48
T4 DNA Ligase - BIOKÉ
https://www.bioke.com/webshop/neb/m0202.html
Catalyzes the formation of a phosphodiester bond between juxtaposed 5' phosphate and 3' hydroxyl termini in duplex DNA or RNA. This enzyme will join blunt ...
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https://www.bioke.com/webshop/neb/m0202.html
Catalyzes the formation of a phosphodiester bond between juxtaposed 5' phosphate and 3' hydroxyl termini in duplex DNA or RNA. This enzyme will join blunt ...
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49
Adapter Ligation technology | Flexibility for many study designs
https://www.illumina.com/techniques/sequencing/ngs-library-prep/ligation.html
Ligation technology is used to construct NGS libraries for sequencing. The process uses an enzyme to connect specialized adapters to both ends of DNA ...
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https://www.illumina.com/techniques/sequencing/ngs-library-prep/ligation.html
Ligation technology is used to construct NGS libraries for sequencing. The process uses an enzyme to connect specialized adapters to both ends of DNA ...
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50
The Ligase Chain Reaction in a PCR World - Genome Res
https://genome.cshlp.org/content/1/1/5.full.pdf
Thermostable DNA ligase will covalent- ly link each set, provided that there is complete complementarity at the junc~ tion. (8) Because the oligonucleotide.
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https://genome.cshlp.org/content/1/1/5.full.pdf
Thermostable DNA ligase will covalent- ly link each set, provided that there is complete complementarity at the junc~ tion. (8) Because the oligonucleotide.
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51
The Sole DNA Ligase in Entamoeba histolytica Is a ... - Frontiers
https://www.frontiersin.org/articles/10.3389/fcimb.2018.00214/full
Nick-sealing fidelity in DNA ligases relates to the extent to which the enzyme can ligate substrates containing mismatched bases on either side ...
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https://www.frontiersin.org/articles/10.3389/fcimb.2018.00214/full
Nick-sealing fidelity in DNA ligases relates to the extent to which the enzyme can ligate substrates containing mismatched bases on either side ...
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52
Ligase Independent Cloning (LIC)
https://www.helmholtz-muenchen.de/fileadmin/PEPF/Protocols/LIC-cloning.pdf
This process is very efficient because only the desired products can form. 1. Preparation of vector DNA. The EMBL-made LIC vectors (see appendix for vectors ...
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https://www.helmholtz-muenchen.de/fileadmin/PEPF/Protocols/LIC-cloning.pdf
This process is very efficient because only the desired products can form. 1. Preparation of vector DNA. The EMBL-made LIC vectors (see appendix for vectors ...
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53
Succinate-CoA ligase deficiency - Genetics - MedlinePlus
https://medlineplus.gov/genetics/condition/succinate-coa-ligase-deficiency/
Succinate-CoA ligase deficiency is an inherited disorder that affects ... Additional features of succinate-CoA ligase deficiency can include ...
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https://medlineplus.gov/genetics/condition/succinate-coa-ligase-deficiency/
Succinate-CoA ligase deficiency is an inherited disorder that affects ... Additional features of succinate-CoA ligase deficiency can include ...
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54
Outline the function of DNA Ligase - MyTutor
https://www.mytutor.co.uk/answers/20999/IB/Biology/Outline-the-function-of-DNA-Ligase/
It is a very important enzyme in DNA replication and DNA repair. Do note that it also helps bond Okazaki fragments, which are short strands of DNA formed on ...
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https://www.mytutor.co.uk/answers/20999/IB/Biology/Outline-the-function-of-DNA-Ligase/
It is a very important enzyme in DNA replication and DNA repair. Do note that it also helps bond Okazaki fragments, which are short strands of DNA formed on ...
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55
How Ligase is Used to Engineer Recombinant DNA - Quizlet
https://quizlet.com/508932413/how-ligase-is-used-to-engineer-recombinant-dna-flash-cards/
DNA ligase. an enzyme that can join two DNA molecules.
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https://quizlet.com/508932413/how-ligase-is-used-to-engineer-recombinant-dna-flash-cards/
DNA ligase. an enzyme that can join two DNA molecules.
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56
LIGATION AND PREVENTION OF SELF - Marcin Filipecki
http://marcin_filipecki.users.sggw.pl/PDFY/Genetic%20engineering/7.pdf
DNA ligase is the enzyme at the heart of the DNA ligation reaction. 3. DNA ligase enzyme: ... molecules will be higher and they would whizz.
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http://marcin_filipecki.users.sggw.pl/PDFY/Genetic%20engineering/7.pdf
DNA ligase is the enzyme at the heart of the DNA ligation reaction. 3. DNA ligase enzyme: ... molecules will be higher and they would whizz.
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57
A DNA Ligase from a Hyperthermophilic Archaeon with ...
https://journals.asm.org/doi/10.1128/JB.182.22.6424-6433.2000
DNA ligase I from humans includes a regulatory domain of 216 amino acid residues in its N-terminal region, which is dispensable for DNA ligase activity in vitro ...
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https://journals.asm.org/doi/10.1128/JB.182.22.6424-6433.2000
DNA ligase I from humans includes a regulatory domain of 216 amino acid residues in its N-terminal region, which is dispensable for DNA ligase activity in vitro ...
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58
9.2 DNA Replication – Concepts of Biology
https://opentextbc.ca/biology/chapter/9-2-dna-replication/
For example, a strand of DNA with a nucleotide sequence of AGTCATGA will have ... and the gaps between fragments are sealed by an enzyme called DNA ligase.
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https://opentextbc.ca/biology/chapter/9-2-dna-replication/
For example, a strand of DNA with a nucleotide sequence of AGTCATGA will have ... and the gaps between fragments are sealed by an enzyme called DNA ligase.
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59
DNA Ligase - UVM Genetics & Genomics Wiki - Fandom
https://uvmgg.fandom.com/wiki/DNA_Ligase
DNA ligase is an enzyme that catalyzes the repair of single-strand breaks by the formation of covalent phosphodiester bonds between adjacent 3'-hydroxyl ...
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https://uvmgg.fandom.com/wiki/DNA_Ligase
DNA ligase is an enzyme that catalyzes the repair of single-strand breaks by the formation of covalent phosphodiester bonds between adjacent 3'-hydroxyl ...
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60
How are the DNA polymerase and the DNA ligase enzymes ...
https://www.numerade.com/ask/question/how-are-the-dna-polymerase-and-the-dna-ligase-enzymes-different-in-their-function-whats-all-that-apply-polymerase-adds-a-new-base-to-an-available-3-end-and-ligase-links-two-nucleotides-that-52561/
Polymerase makes phosphodiester bonds and ligases make nucleotidyl linkages. Ligase is used to join Okazaki fragments together on the lagging ...
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https://www.numerade.com/ask/question/how-are-the-dna-polymerase-and-the-dna-ligase-enzymes-different-in-their-function-whats-all-that-apply-polymerase-adds-a-new-base-to-an-available-3-end-and-ligase-links-two-nucleotides-that-52561/
Polymerase makes phosphodiester bonds and ligases make nucleotidyl linkages. Ligase is used to join Okazaki fragments together on the lagging ...
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61
What Is the Function of the Enzyme Ligase in Forming ...
https://sciencing.com/function-enzyme-ligase-forming-recombinant-dna-23090.html
In your body, DNA has been duplicated trillions of times. Proteins do that job, and one of those proteins is an enzyme called DNA ligase.
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https://sciencing.com/function-enzyme-ligase-forming-recombinant-dna-23090.html
In your body, DNA has been duplicated trillions of times. Proteins do that job, and one of those proteins is an enzyme called DNA ligase.
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62
DNA Ligase - Synopsis - BYJU'S
https://byjus.com/neet/dna-ligase/
DNA ligases indicate the basic class of enzymes necessary for all entities to sustain the structural integrity of the genome. This enzyme connects two strands ...
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https://byjus.com/neet/dna-ligase/
DNA ligases indicate the basic class of enzymes necessary for all entities to sustain the structural integrity of the genome. This enzyme connects two strands ...
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63
DNA Ligase: Getting a Grip to Seal the Deal
https://www.cell.com/current-biology/pdf/S0960-9822(05)00085-0.pdf
DNA ligation is the last step in a ... T. filiformis ligase is analogous to the Lig1 DBD, but must undergo a large ... Ligases do not bind tightly to.
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https://www.cell.com/current-biology/pdf/S0960-9822(05)00085-0.pdf
DNA ligation is the last step in a ... T. filiformis ligase is analogous to the Lig1 DBD, but must undergo a large ... Ligases do not bind tightly to.
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64
definition of ligase by Medical dictionary
https://medical-dictionary.thefreedictionary.com/ligase
DNA ligase either of two enzymes that join two double-helical molecules of DNA together to make a longer DNA molecule. ligase chain reaction a type of DNA ...
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https://medical-dictionary.thefreedictionary.com/ligase
DNA ligase either of two enzymes that join two double-helical molecules of DNA together to make a longer DNA molecule. ligase chain reaction a type of DNA ...
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65
What does ligase mean? - Definitions.net
https://www.definitions.net/definition/ligase
In molecular biology, DNA ligase is a specific type of enzyme, a ligase, that facilitates the joining of DNA strands together by catalyzing the formation of ...
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https://www.definitions.net/definition/ligase
In molecular biology, DNA ligase is a specific type of enzyme, a ligase, that facilitates the joining of DNA strands together by catalyzing the formation of ...
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66
ENZYME RESOURCE GUIDE - Ligases
https://www.promega.com/-/media/files/resources/product-guides/cloning-enzymes/ligases.pdf?la=en
coli DNA ligase (which, like most prokaryotic DNA ligases uses NAD as a cofactor instead of ATP) can sometimes be used in place of T4 DNA ligase for ligation of ...
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https://www.promega.com/-/media/files/resources/product-guides/cloning-enzymes/ligases.pdf?la=en
coli DNA ligase (which, like most prokaryotic DNA ligases uses NAD as a cofactor instead of ATP) can sometimes be used in place of T4 DNA ligase for ligation of ...
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67
Notes on Restriction enzymes and DNA Ligases
https://www.biologyexams4u.com/2022/08/restriction-enzymes-and-dna-ligases.html
Ligases are Joining enzyme that joins DNA fragments by forming phosphodiester bond. The process is called ligation. How DNA ligase works? How DNA ligase ...
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https://www.biologyexams4u.com/2022/08/restriction-enzymes-and-dna-ligases.html
Ligases are Joining enzyme that joins DNA fragments by forming phosphodiester bond. The process is called ligation. How DNA ligase works? How DNA ligase ...
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68
DNA ligase definition
https://groups.molbiosci.northwestern.edu/holmgren/Glossary/Definitions/Def-D/DNA_ligase.html
› Def-D › D...
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https://groups.molbiosci.northwestern.edu/holmgren/Glossary/Definitions/Def-D/DNA_ligase.html
› Def-D › D...
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69
What is DNA ligase? And what is it used for? - AAT Bioquest
https://www.aatbio.com/resources/faq-frequently-asked-questions/What-is-DNA-ligase-And-what-is-it-used-for
DNA ligase a specific type of enzyme that joins DNA strands together by catalyzing the formation of phosphodiester bond. It can repair ...
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https://www.aatbio.com/resources/faq-frequently-asked-questions/What-is-DNA-ligase-And-what-is-it-used-for
DNA ligase a specific type of enzyme that joins DNA strands together by catalyzing the formation of phosphodiester bond. It can repair ...
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70
Human DNA ligase I completely encircles and partially ...
https://www.nature.com/articles/nature03082
Several aspects of the fidelity of DNA ligation can be explained by the distorted conformation of DNA bound to Lig1. Most DNA ligases ...
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https://www.nature.com/articles/nature03082
Several aspects of the fidelity of DNA ligation can be explained by the distorted conformation of DNA bound to Lig1. Most DNA ligases ...
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71
DNA Ligation - NEB
https://www.neb.com/applications/cloning-and-synthetic-biology/dna-ligation
Ligation of DNA is a critical step in many modern molecular biology workflows. The sealing of nicks between adjacent residues of a single-strand break on a ...
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https://www.neb.com/applications/cloning-and-synthetic-biology/dna-ligation
Ligation of DNA is a critical step in many modern molecular biology workflows. The sealing of nicks between adjacent residues of a single-strand break on a ...
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72
DNA Ligase: Structure, Mechanism, and Function - Science
https://www.science.org/doi/10.1126/science.186.4166.790
coli chromosome. DNA ligase is therefore an essential enzyme required for normal DNA replication and repair in E. coli. Purified DNA ligases have proved to be ...
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https://www.science.org/doi/10.1126/science.186.4166.790
coli chromosome. DNA ligase is therefore an essential enzyme required for normal DNA replication and repair in E. coli. Purified DNA ligases have proved to be ...
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73
What is the Role of BRCA1 in Normal Cells? - News Medical
https://www.news-medical.net/health/What-is-the-Role-of-BRCA1-in-Normal-Cells.aspx
A damaging BRCA1 mutation can be inherited from a parent. ... The BRCA1 protein is an E3 uniquitin-protein ligase that regulates the creation of ...
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https://www.news-medical.net/health/What-is-the-Role-of-BRCA1-in-Normal-Cells.aspx
A damaging BRCA1 mutation can be inherited from a parent. ... The BRCA1 protein is an E3 uniquitin-protein ligase that regulates the creation of ...
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74
Genome-scale profiling of histone H3.3 replacement patterns
https://www.gs.washington.edu/academics/courses/braun/55106/readings/mito.pdf
independent assembly can be distinguished from replication- ... together with Escherichia coli biotin ligase in D. melanogaster S2 cells.
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https://www.gs.washington.edu/academics/courses/braun/55106/readings/mito.pdf
independent assembly can be distinguished from replication- ... together with Escherichia coli biotin ligase in D. melanogaster S2 cells.
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75
Ligase - bionity.com
https://www.bionity.com/en/encyclopedia/Ligase.html
In biochemistry, a ligase (from the Latin verb ligāre — "to bind" or "to glue together") is an enzyme that can catalyse the joining of the sugar phosphate ...
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https://www.bionity.com/en/encyclopedia/Ligase.html
In biochemistry, a ligase (from the Latin verb ligāre — "to bind" or "to glue together") is an enzyme that can catalyse the joining of the sugar phosphate ...
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76
what would be a good hypothesis for tgis experiment - Chegg
https://www.chegg.com/homework-help/questions-and-answers/would-good-hypothesis-tgis-experiment-yeast-cloning-q105499909
A restriction enzyme EcoRI was used in order to cut the plasmid or DNA into multiple restriction fragments prior to the DNA ligase joining the insert to the ...
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https://www.chegg.com/homework-help/questions-and-answers/would-good-hypothesis-tgis-experiment-yeast-cloning-q105499909
A restriction enzyme EcoRI was used in order to cut the plasmid or DNA into multiple restriction fragments prior to the DNA ligase joining the insert to the ...
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77
trna function quizlet
https://almiratravel.co.id/7urronl/trna-function-quizlet
The product of transcription is RNA, which can be encountered in the form mRNA, ... Lagging strand, DNA ligase, and discontinuous.
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https://almiratravel.co.id/7urronl/trna-function-quizlet
The product of transcription is RNA, which can be encountered in the form mRNA, ... Lagging strand, DNA ligase, and discontinuous.
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78
cysteine disulfide bond formation
https://meu.niveldeingles.com.br/chuolwtr/cysteine-disulfide-bond-formation
Protein primary structures can be Glutamatecysteine ligase (GCL) EC 6.3.2.2), previously known as -glutamylcysteine synthetase (GCS), is the first enzyme of the ...
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https://meu.niveldeingles.com.br/chuolwtr/cysteine-disulfide-bond-formation
Protein primary structures can be Glutamatecysteine ligase (GCL) EC 6.3.2.2), previously known as -glutamylcysteine synthetase (GCS), is the first enzyme of the ...
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79
Disentangling the complex gene interaction networks between ...
https://www.biorxiv.org/content/10.1101/2022.07.19.500555v2
Studies focused solely on single organisms can fail to identify the ... E3 ubiquitin ligase PUB4 regulates BIK1 homeostasis and is targeted ...
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https://www.biorxiv.org/content/10.1101/2022.07.19.500555v2
Studies focused solely on single organisms can fail to identify the ... E3 ubiquitin ligase PUB4 regulates BIK1 homeostasis and is targeted ...
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80
MRC CMBI (@CMBI_Imperial) / Twitter
https://twitter.com/cmbi_imperial?lang=en
If you love working out the molecular nitty gritty of host pathogen interactions and want to know if you can reprogram a kinase then come join the lab - we ...
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https://twitter.com/cmbi_imperial?lang=en
If you love working out the molecular nitty gritty of host pathogen interactions and want to know if you can reprogram a kinase then come join the lab - we ...
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81
Genome-wide kinetics of DNA excision repair in relation to ...
https://core.ac.uk/download/pdf/304666356.pdf
transcribed, damage recognition can also be achieved by a stalled ... This immunoprecipitation was followed by ligation of.
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https://core.ac.uk/download/pdf/304666356.pdf
transcribed, damage recognition can also be achieved by a stalled ... This immunoprecipitation was followed by ligation of.
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82
XtalPi, CK Life Sciences to develop AI-driven tumour vaccine ...
https://www.pharmaceutical-technology.com/news/xtalpi-tumour-vaccine-platform/
Such a platform will aid in boosting tumour vaccine discovery and ... Ubiquitin Protein Ligase E3A (Renal Carcinoma Antigen NY REN 54 or ...
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https://www.pharmaceutical-technology.com/news/xtalpi-tumour-vaccine-platform/
Such a platform will aid in boosting tumour vaccine discovery and ... Ubiquitin Protein Ligase E3A (Renal Carcinoma Antigen NY REN 54 or ...
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83
BIOTECHNOLOGY / LIGATION - Pathwayz
https://www.pathwayz.org/Tree/Plain/LIGATION
DNA ligases are a class of enzymes that can fix breaks or link together DNA strands. They are involved in DNA repair, DNA replication (link Okazaki ...
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https://www.pathwayz.org/Tree/Plain/LIGATION
DNA ligases are a class of enzymes that can fix breaks or link together DNA strands. They are involved in DNA repair, DNA replication (link Okazaki ...
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84
Which of the following statement is correct mcq
https://sebastian-topshop.de/which-of-the-following-statement-is-correct-mcq.htm
(A) It can carry out only blunt ended ligations - (B) It doesn't requires ATP ... of the following statements is correct with respect to T4 DNA ligase?
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https://sebastian-topshop.de/which-of-the-following-statement-is-correct-mcq.htm
(A) It can carry out only blunt ended ligations - (B) It doesn't requires ATP ... of the following statements is correct with respect to T4 DNA ligase?
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85
S - Spike glycoprotein | UniProtKB - UniProt
https://www.uniprot.org/uniprotkb/P0DTC2/entry
Contains a viral fusion peptide that is unmasked after S2 cleavage. This cleavage can occur at the cell membrane by host TMPRSS2 or during endocytosis by host ...
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https://www.uniprot.org/uniprotkb/P0DTC2/entry
Contains a viral fusion peptide that is unmasked after S2 cleavage. This cleavage can occur at the cell membrane by host TMPRSS2 or during endocytosis by host ...
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86
Dr Yu-Chiang Lai PhD - University of Birmingham
https://www.birmingham.ac.uk/staff/profiles/sportex/lai-yu-chiang.aspx
Cookies settings. We use cookies to help make improvements and deliver personalised content to you here and on other websites. You can control the types of ...
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https://www.birmingham.ac.uk/staff/profiles/sportex/lai-yu-chiang.aspx
Cookies settings. We use cookies to help make improvements and deliver personalised content to you here and on other websites. You can control the types of ...
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87
A Quantitative Spatial Proteomics Analysis of ... - Lamond Lab
https://www.lamondlab.com/newwebsite/publication%20PDFs%20for%20webpage/PMID_21937730%20Boisvert_Ahmad_2011.pdf
Cells can regulate proteins via phosphorylation and other ... sequestration of the E3 ligase mdm2, causing a rapid increase in p53 levels ...
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https://www.lamondlab.com/newwebsite/publication%20PDFs%20for%20webpage/PMID_21937730%20Boisvert_Ahmad_2011.pdf
Cells can regulate proteins via phosphorylation and other ... sequestration of the E3 ligase mdm2, causing a rapid increase in p53 levels ...
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88
Molecular Cell Biology - Page 1-178 - Google Books Result
https://books.google.com/books?id=K3JbjG1JiUMC&pg=SA1-PA178&lpg=SA1-PA178&dq=what+does+ligase+do&source=bl&ots=asHdVSAsaB&sig=ACfU3U2PtG9v6Nr5tMJpwr400gVmpPnHrw&hl=en&sa=X&ved=2ahUKEwifs4fY_877AhXBHzQIHZbqA3UQ6AF6BQjRAhAD
In addition to ligating complementary sticky ends , the DNA ligase from bacteriophage T4 can ligate any two blunt DNA ends . However , blunt - end ligation ...
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https://books.google.com/books?id=K3JbjG1JiUMC&pg=SA1-PA178&lpg=SA1-PA178&dq=what+does+ligase+do&source=bl&ots=asHdVSAsaB&sig=ACfU3U2PtG9v6Nr5tMJpwr400gVmpPnHrw&hl=en&sa=X&ved=2ahUKEwifs4fY_877AhXBHzQIHZbqA3UQ6AF6BQjRAhAD
In addition to ligating complementary sticky ends , the DNA ligase from bacteriophage T4 can ligate any two blunt DNA ends . However , blunt - end ligation ...
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89
Polynucleotide Ligases—Advances in Research and Application: ...
https://books.google.com/books?id=bCjo5K6ADpQC&pg=PA26&lpg=PA26&dq=what+does+ligase+do&source=bl&ots=jkQ3KJCZvi&sig=ACfU3U2Jb73aUJRQH6cxoT518X9RzseBYg&hl=en&sa=X&ved=2ahUKEwifs4fY_877AhXBHzQIHZbqA3UQ6AF6BQjlAhAD
... XRCC4-DNA ligase IV do not modulate PALF nuclease activity on single-stranded DNA or overhangs of duplex substrates. PALF does not open DNA hair-pins.
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https://books.google.com/books?id=bCjo5K6ADpQC&pg=PA26&lpg=PA26&dq=what+does+ligase+do&source=bl&ots=jkQ3KJCZvi&sig=ACfU3U2Jb73aUJRQH6cxoT518X9RzseBYg&hl=en&sa=X&ved=2ahUKEwifs4fY_877AhXBHzQIHZbqA3UQ6AF6BQjlAhAD
... XRCC4-DNA ligase IV do not modulate PALF nuclease activity on single-stranded DNA or overhangs of duplex substrates. PALF does not open DNA hair-pins.
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90
The Biochemistry of the Nucleic Acids - Page 183 - Google Books Result
https://books.google.com/books?id=DLfwCAAAQBAJ&pg=PA183&lpg=PA183&dq=what+does+ligase+do&source=bl&ots=sr5UDC5e-G&sig=ACfU3U07gZgoXyOzRmX2VKeLwXR587ZPTQ&hl=en&sa=X&ved=2ahUKEwifs4fY_877AhXBHzQIHZbqA3UQ6AF6BQjUAhAD
There are normally about 300 molecules of ligase per cell, ... a T4-specified ligase which, in addition to joining two DNA chains, will also join RNA to DNA ...
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https://books.google.com/books?id=DLfwCAAAQBAJ&pg=PA183&lpg=PA183&dq=what+does+ligase+do&source=bl&ots=sr5UDC5e-G&sig=ACfU3U07gZgoXyOzRmX2VKeLwXR587ZPTQ&hl=en&sa=X&ved=2ahUKEwifs4fY_877AhXBHzQIHZbqA3UQ6AF6BQjUAhAD
There are normally about 300 molecules of ligase per cell, ... a T4-specified ligase which, in addition to joining two DNA chains, will also join RNA to DNA ...
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91
Dislocation and Degradation of Proteins from the Endoplasmic ...
https://books.google.com/books?id=vdZlqAJBDtoC&pg=PA79&lpg=PA79&dq=what+does+ligase+do&source=bl&ots=869DhLmMiF&sig=ACfU3U07O2k306QMavHe9_h6Fp6C2_XU1g&hl=en&sa=X&ved=2ahUKEwifs4fY_877AhXBHzQIHZbqA3UQ6AF6BQjQAhAD
of cytosolic MATα2 under influence of the ER-integrated ubiquitin ligase Doa10p ... TCR-α can be targeted for degradation by Fbx2, Fbx6, and HRD1 ligases.
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https://books.google.com/books?id=vdZlqAJBDtoC&pg=PA79&lpg=PA79&dq=what+does+ligase+do&source=bl&ots=869DhLmMiF&sig=ACfU3U07O2k306QMavHe9_h6Fp6C2_XU1g&hl=en&sa=X&ved=2ahUKEwifs4fY_877AhXBHzQIHZbqA3UQ6AF6BQjQAhAD
of cytosolic MATα2 under influence of the ER-integrated ubiquitin ligase Doa10p ... TCR-α can be targeted for degradation by Fbx2, Fbx6, and HRD1 ligases.
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92
Cbl Proteins - Page 116 - Google Books Result
https://books.google.com/books?id=IVxr18EwGq4C&pg=PA116&lpg=PA116&dq=what+does+ligase+do&source=bl&ots=aysFVs_qVV&sig=ACfU3U06b4xRk_-ziIZLzEvTA7SeCExDMw&hl=en&sa=X&ved=2ahUKEwifs4fY_877AhXBHzQIHZbqA3UQ6AF6BQjSAhAD
In addition , are these phenotypes due primarily to loss of E3 ubiquitin ligase activity or do they reflect other functional responsibilities of Cbl ...
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In addition , are these phenotypes due primarily to loss of E3 ubiquitin ligase activity or do they reflect other functional responsibilities of Cbl ...
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