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1 Treatments for Alpha-1 (Alpha-1 Antitrypsin Deficiency)
https://www.webmd.com/lung/copd/treatments
There's only one specific treatment to fight alpha 1: augmentation therapy. It's also called replacement therapy. It's been around for 25 years, ...
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2 Alpha-1 Antitrypsin Deficiency Treatment Options
https://www.templehealth.org/services/conditions/alpha-1-antitrypsin-deficiency/treatment-options
The only specific treatment for alpha-1 antitrypsin deficiency (AATD) is augmentation therapy, but there is no cure.
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3 Treating and Managing Alpha-1 Antitrypsin Deficiency
https://www.lung.org/lung-health-diseases/lung-disease-lookup/alpha-1-antitrypsin-deficiency/treating-and-managing
Your treatment may include prescribed inhaled medications to control symptoms of COPD, referral to a pulmonary rehabilitation program, oxygen therapy, and ...
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4 Alpha-1 Antitrypsin Deficiency: Causes, Symptoms & Treatment
https://my.clevelandclinic.org/health/diseases/21175-alpha-1-antitrypsin-deficiency
If you have emphysema due to very low levels of Alpha-1 in your blood, they may recommend augmentation therapy. Augmentation therapy delivers ...
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5 Treatment of alpha-1 antitrypsin deficiency - UpToDate
https://www.uptodate.com/contents/treatment-of-alpha-1-antitrypsin-deficiency
The goal of most specific treatment approaches for AAT deficiency is to raise the serum AAT level (and therefore the concentration of AAT in the ...
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6 Alpha-1-antitrypsin deficiency treatment | Asthma + Lung UK
https://www.blf.org.uk/support-for-you/alpha-1-antitrypsin-deficiency/treatment
AAT augmentation therapy is a treatment where alpha-1-antitrypsin (AAT) is given into your veins to increase the levels in your body. The idea is to try to slow ...
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7 COPD - Alpha-1 Antitrypsin Deficiency | NHLBI, NIH
https://www.nhlbi.nih.gov/health/alpha-1-antitrypsin-deficiency
There is no cure for AAT deficiency, but there are treatments to slow the lung damage it causes. You may need a lifelong treatment called ...
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8 Alpha1-Antitrypsin (AAT) Deficiency Treatment & Management
https://emedicine.medscape.com/article/295686-treatment
It also is heat-treated as an additional precaution against transmission of infection. The US Food and Drug Administration (FDA) has approved 2 ...
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9 Alpha-1 Antitrypsin Deficiency Treatment - The Lung Docs
https://www.thelungdocs.com/services/aatd/alpha-1-antitrypsin-deficiency-treatment/
There are currently four Alpha-1 antitrypsin therapy products used in treatment in the U.S.: Prolastin-C® and Prolastin-C Liquid® from Grifols, Aralast NP™ from ...
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10 Enzyme Replacement Therapy for Alpha-1 Antitrypsin ...
https://infusionassociates.com/infusion-therapy/ert-for-alpha-1-antitrypsin-deficiency/
Traditional forms of treatment for alpha-1 antitrypsin deficiency include oral medications and oxygen therapy. For those for whom such treatments have failed, ...
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11 Alpha -1 Antitrypsin Deficiency - St Vincent's Lung Health
https://www.svhlunghealth.com.au/conditions/alpha-1-antitrypsin-deficiency
What are the possible procedures and treatments for Alpha-1 Antitrypsin Deficiency? · Quitting smoking · Bronchodilators · Antibiotics · Augmentation therapy · Lung ...
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12 Alpha-1 Antitrypsin Deficiency - NORD (National Organization ...
https://rarediseases.org/rare-diseases/alpha-1-antitrypsin-deficiency/
No specific therapy is available for the liver disease associated with A1AD, though animal studies have shown promise for several drugs that can increase the ...
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13 Alpha-1 Proteinase Inhibitor Human (Intravenous Route)
https://www.mayoclinic.org/drugs-supplements/alpha-1-proteinase-inhibitor-human-intravenous-route/description/drg-20061630
Alpha-1 proteinase inhibitor injection, also called alpha 1-PI, is used to treat a certain type of emphysema (a lung condition). The emphysema is caused by ...
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14 Alpha-1 Antitrypsin Deficiency
https://www.chop.edu/conditions-diseases/alpha-1-antitrypsin-deficiency
Treatment for AATD. Currently, there is no known cure for alpha-1 antitrypsin deficiency. A number of treatments exist to help patients manage symptoms of this ...
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15 6: New and emerging treatments for α1-antitrypsin deficiency
https://thorax.bmj.com/content/59/10/904
Most treatment of affected individuals is not specifically directed at AAT deficiency but focuses on the resultant disease state. The only currently available ...
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16 Alpha-1 Antitrypsin Deficiency - MedlinePlus
https://medlineplus.gov/alpha1antitrypsindeficiency.html
Blood tests and genetic tests can tell if you have it. If your lungs are affected, you may also have lung tests. Treatments include medicines, ...
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17 Augmentation therapy for alpha-1 antitrypsin deficiency
https://ojrd.biomedcentral.com/articles/10.1186/1750-1172-8-149
Intravenous augmentation therapy is the only specific treatment available for emphysema associated with alpha-1 antitrypsin deficiency.
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18 Alpha-1 Antitrypsin Deficiency: Home Therapy - Frontiers
https://www.frontiersin.org/articles/10.3389/fphar.2021.575402/full
Over the last few months, the SARS-CoV2 pandemic has had an impact on chronic therapies in patients with rare disease, such as alpha-1 ...
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19 Alpha-1 antitrypsin deficiency research and emerging ...
https://journals.sagepub.com/doi/full/10.1177/20406223211014025
Intravenous infusion of alpha-1 antitrypsin (AAT) was approved by the United States Food and Drug Administration (FDA) to treat emphysema associated with ...
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20 Pediatric Alpha-1 Antitrypsin Deficiency | Children's Pittsburgh
https://www.chp.edu/our-services/transplant/liver/education/liver-disease-states/alpha-1-antitrypsin-deficiency
There is no specific treatment for liver disease associated with alpha-1 antitrypsin deficiency; clinical care primarily treats symptoms as they occur and ...
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21 Alpha-1 Antitrypsin Deficiency - Symptoms and Causes
https://www.pennmedicine.org/for-patients-and-visitors/patient-information/conditions-treated-a-to-z/alpha-1-antitrypsin-deficiency
Treatment for AAT deficiency involves replacing the missing AAT protein. The protein is given through a vein each week or every 4 weeks. This is only slightly ...
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22 diagnosis and treatment of pulmonary disease in α1 ...
https://erj.ersjournals.com/content/50/5/1700610
Since augmentation is currently the only specific therapy for AATD, it has been a topic of intense debate in the literature and the subject of numerous review ...
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23 Systemic modified messenger RNA for replacement therapy in ...
https://www.nature.com/articles/s41598-020-64017-0
Alpha 1-antitrypsin (AAT) deficiency arises from an inherited mutation in the SERPINA1 gene. The disease causes damage in the liver where ...
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24 Alpha-1 Antitrypsin Deficiency - Pulmonary Disorders
https://www.merckmanuals.com/professional/pulmonary-disorders/chronic-obstructive-pulmonary-disease-and-related-disorders/alpha-1-antitrypsin-deficiency
Serum alpha-1 antitrypsin level < 11 mmol/L (< 80 mg/dL) confirms the diagnosis. Treatment is smoking cessation, bronchodilators, early treatment of infection, ...
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25 Alpha-1 antitrypsin deficiency - HSE.ie
https://www2.hse.ie/conditions/alpha-1-antitrypsin-deficiency/
Treatment for AAT deficiency · medicines called inhaled bronchodilators and inhaled steroids - these medicines help open your airways and make breathing easier ...
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26 Intravenous alpha-1 antitrypsin augmentation therapy for ...
https://www.cochrane.org/CD007851/AIRWAYS_intravenous-alpha-1-antitrypsin-augmentation-therapy-treating-patients-alpha-1-antitrypsin
Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease · Background.
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27 Alpha-1 antitrypsin deficiency: An underrecognized, treatable ...
https://www.ccjm.org/content/83/7/507
Specific therapy for alpha-1 antitrypsin deficiency currently involves weekly intravenous infusions of purified, pooled human-plasma-derived ...
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28 Alpha-1 Antitrypsin (AAT) Deficiency - Dignity Health
https://www.dignityhealth.org/arizona/locations/stjosephs/services/lung-disease-thoracic-disorders/conditions-treatments/alpha-1
The primary treatment for alpha-1 antitrypsin deficiency disorder is management of the lung disorder with bronchodilators, inhaled steroids, ...
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29 The Biological Effects of Double-Dose Alpha-1 Antitrypsin ...
https://www.atsjournals.org/doi/10.1164/rccm.201901-0010OC
AAT (alpha-1 antitrypsin) has antiinflammatory and immunomodulatory functions, in addition to antiprotease properties. Augmentation therapy with ...
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30 Alpha-1 Antitrypsin Deficiency Clinical Practice Guidelines
https://journal.copdfoundation.org/jcopdf/id/1115/The-Diagnosis-and-Management-of-Alpha-1-Antitrypsin-Deficiency-in-the-Adult
Intravenous augmentation therapy in those with AATD is recommended for: Individuals with an FEV1 less than or equal to 65% predicted. For those with lung ...
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31 About Alpha-1 Antitrypsin Deficiency
https://www.genome.gov/Genetic-Disorders/Alpha-1-Antitrypsin-Deficiency
There is currently no cure. The major goal of AATD management is preventing or slowing the progression of lung disease. Treatments include ...
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32 Experimental Gene Transfer Procedure to Treat Alpha 1 ...
https://www.clinicaltrials.gov/ct2/show/NCT00430768
Individuals with a deficiency of the alpha 1-antitrypsin (AAT) protein are at risk for developing emphysema and liver damage. Researchers have developed a ...
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33 Augmentation Therapy for Patients with Alpha-1 - Prolastin C
https://www.prolastin.com/en/hcp/alpha-1-treatment
Augmentation therapy is the only treatment specifically approved for adults with emphysema due to severe deficiency of alpha-1 protein · The intended theoretical ...
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34 Obstacles to Early Diagnosis and Treatment of Alpha-1 ...
https://www.dovepress.com/obstacles-to-early-diagnosis-and-treatment-of-alpha-1-antitrypsin-defi-peer-reviewed-fulltext-article-TCRM
With respect to treatment, AATD involves treating two separate pathologies, lung disease and liver disease. The only specific AATD treatment, ...
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35 Updates in the Management of Alpha-1 Antitrypsin Deficiency ...
https://www.touchrespiratory.com/copd/journal-articles/updates-in-the-management-of-alpha-1-antitrypsin-deficiency-lung-disease/
Short of a curative approach, alpha-1 antitrypsin deficiency lung disease benefits from standard medical treatment with inhaled ...
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36 Health Library Alpha-1 Antitrypsin Deficiency (AATD)
https://www.cincinnatichildrens.org/health/a/alpha
There is no cure for AATD. If severe liver disease develops, a liver transplant is currently the only option available for survival. The goal of treatment is to ...
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37 Alpha-1 Antitrypsin Deficiency - UChicago Medicine
https://www.uchicagomedicine.org/conditions-services/lung-diseases/alpha-1-antitrypsin-deficiency
UChicago Medicine's Alpha-1 antitrypsin deficiency program gives patients access to leading-edge interventions that are only available at select medical ...
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38 Alpha-1 Liver Disease Treatment - National Jewish Health
https://www.nationaljewish.org/conditions/alpha-1/alpha-1-overview/alpha-1-liver-disease/treatment
Severe infant liver failure in Alpha-1 is always treated with liver transplantation, which cures the disease by replacing the failing liver with ...
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39 Alpha 1-Antitrypsin Deficiency Program | UC San Diego Health
https://health.ucsd.edu/specialties/pulmonary/advanced-lung-disease/pages/alpha1-deficiency.aspx
Alpha-1 antitrypsin (AAT) deficiency is a relatively common genetic condition that is often under-recognized. Alpha-1 antitrypsin is a protein that protects us ...
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40 Review Alpha-1 Antitrypsin Deficiency: Pathogenesis, Clinical ...
https://www.sciencedirect.com/science/article/pii/S000293430700736X
Diagnosis of alpha-1 antitrypsin deficiency can be established by measurement of the serum alpha-1 antitrypsin concentration or by genetic analysis. Treatment ...
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41 Liver Disease from Alpha-1 Antitrypsin Deficiency - Healthline
https://www.healthline.com/health/alpha-1-liver-disease
What is the treatment for alpha-1 antitrypsin deficiency liver disease? · eating a balanced diet; getting plenty of exercise; taking steps to ...
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42 Alpha-1 Antitrypsin Deficiency - causes, symptoms ... - YouTube
https://www.youtube.com/watch?v=pXR0RpMMrfk
Nov 5, 2018
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43 Alpha-1 Antitrypsin Deficiency - Allergy & Asthma Network
https://allergyasthmanetwork.org/health-a-z/alpha-1-antitrypsin-deficiency/
There is no cure for alpha-1 antitrypsin deficiency, but medications are available to address inflammation and improve breathing. Alpha-1 patients require the ...
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44 Alpha-1 antitrypsin deficiency - Wikipedia
https://en.wikipedia.org/wiki/Alpha-1_antitrypsin_deficiency
Treatment of lung disease may include bronchodilators, inhaled steroids, and, when infections occur, antibiotics. ... Intravenous infusions of the A1AT protein or ...
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45 Alpha 1 Antitrypsin Deficiency - CSL Behring
https://www.cslbehring.com/patients/find-your-disease/alpha-1-antitrypsin-deficiency
We have therapies to treat Alpha 1 Antitrypsin Deficiency (AATD), a genetic disease exposing lungs to possible excessive inflammation.
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46 Current and Emerging Treatments for Alpha-1 Antitrypsin ...
https://www.gastroenterologyandhepatology.net/archives/july-2016/current-and-emerging-treatments-for-alpha-1-antitrypsin-deficiency/
There are currently no other established therapies to treat liver disease in patients with alpha-1 antitrypsin deficiency. G&H What treatments are currently ...
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47 Alpha-1 antitrypsin deficiency Information - Mount Sinai
https://www.mountsinai.org/health-library/diseases-conditions/alpha-1-antitrypsin-deficiency
Treatment for AAT deficiency involves replacing the missing AAT protein. The protein is given through a vein each week or every 4 weeks. This is only slightly ...
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48 Alpha 1 antitrypsin deficiency - Orphanet
https://www.orpha.net/consor/www/cgi-bin/OC_Exp.php?lng=EN&Expert=60
There is currently no curative treatment. Treatment is similar to that used for COPD and emphysema and aims at reducing symptoms and slowing progression. Long- ...
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49 Alpha-1 Antitrypsin Deficiency - UAB Medicine
https://www.uabmedicine.org/patient-care/conditions/alpha-1-antitrypsin-deficiency
People with AATD and cirrhosis also can develop liver cancer (hepatocellular carcinoma). There is no cure for AATD, but it may be treated with regular ...
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50 Augmentation Therapy - Alpha1-antitrypsin (AAT) deficiency
https://www.thinkalpha1.com/alpha-1-antitrypsin-deficiency-treatment
Augmentation therapy is the only specific treatment for alpha1-antitrypsin (AAT) deficiency ... Intravenous infusion of AAT, also known as augmentation therapy, ...
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51 Consequences of Abrupt Cessation of Alpha 1 -Antitrypsin ...
https://www.nejm.org/doi/full/10.1056/NEJMc1915484
In February 2017, Irish health care policymakers opted against reimbursement for intravenous augmentation therapy with plasma-purified AAT for ...
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52 Alpha-1 Antitrypsin Deficiency | UPMC Center for Liver Disease
https://www.upmc.com/services/digestive-disorders-center/services/liver-diseases/conditions/genetic-liver-diseases/a1at-deficiency
If you develop severe liver cirrhosis, you may need a liver transplant. Medicine to treat A1AT. The most common treatment for this disease is A1AT augmentation ...
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53 Alpha-1 Antitrypsin Deficiency | Conditions and Treatments
https://columbiasurgery.org/conditions-and-treatments/alpha-1-antitrypsin-deficiency
Currently, there is no cure for AAT deficiency. But treatments are available to help manage this condition and reduce its symptoms. Depending on its severity, ...
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54 Alpha-1 Antitrypsin (AAT) Deficiency | Liver Care - Bon Secours
https://www.bonsecours.com/health-care-services/liver-care-hepatology/conditions/alpha-1-antitrypsin-deficiency
Treatment for AAT deficiency is called augmentation therapy and involves receiving regular AAT supplementation through a vein. Overview. In alpha-1 antitrypsin ...
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55 Alpha-1 Antitrypsin Deficiency Market and Key Companies
https://www.delveinsight.com/blog/alpha-1-antitrypsin-deficiency-treatment-market-and-key-companies
What are the key companies working in the Alpha-1 Antitrypsin Deficiency market? ; DCR-A1AT, Dicerna Pharmaceuticals, Phase I and Phase I/II.
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56 Alpha-1 Antitrypsin Deficiency | Riley Children's Health
https://www.rileychildrens.org/health-info/alpha-1-antitrypsin-deficiency
Treatments. There is no treatment for alpha-1 antitrypsin deficiency. Scientists are actively working to discover a treatment for this liver disease. However, ...
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57 What to know about alpha-1 antitrypsin deficiency
https://www.medicalnewstoday.com/articles/alpha-1-antitrypsin-deficiency
Treatment · oxygen therapy · bronchodilators · inhaled steroids · pulmonary rehabilitation · lung transplants · liver transplants.
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58 Entrance of novel therapies drives alpha-1 antitrypsin ...
https://www.pharmaceutical-technology.com/comment/novel-therapies-alpha-1-antitrypsin-deficiency/
The current treatment for AATD involves the use of augmentation therapy, alpha-1 proteinase inhibitors (AI-PIs), whereby patients are ...
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59 Alpha-1 in the European Union Expert Recommendations
https://www.ft.dk/samling/20151/almdel/SUU/bilag/480/1613994.pdf
Alpha-1 antitrypsin deficiency (Alpha-1) is a rare genetic condition that can cause ultra-rare ... There is currently no cure for Alpha-1, but appropriate.
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60 Anti-Proteases and Alpha-1 Antitrypsin Augmentation Therapy
https://rc.rcjournal.com/content/63/6/690
The natural history of alpha-1 antitrypsin deficiency is clearly better when individuals avoid fumes, particulates, and tobacco. Vaccinations ...
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61 Alpha-1 antitrypsin deficiency - Healthdirect
https://www.healthdirect.gov.au/alpha-1-antitrypsin-deficiency
Alpha-1 replacement or augmentation therapy can be used to treat emphysema symptoms related to AATD and is used under special circumstances.
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62 Alpha-1 Antitrypsin Deficiency in Children - SSM Health
https://www.ssmhealth.com/cardinal-glennon/pediatric-gastroenterology/liver-diseases/alpha-1-antitrypsin-deficiency-children
While there is no cure for Alpha-1, we offer the most advanced treatment options and follow-up care to keep your child as healthy as possible. Our team might ...
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63 Role of alpha‐1 antitrypsin in human health and disease
https://onlinelibrary.wiley.com/doi/full/10.1111/joim.12239
In summary, intravenous AAT augmentation for chronic treatment of emphysema due to AAT deficiency has been proven to be safe. No cases have been ...
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64 Gene therapy for alpha 1-antitrypsin deficiency with an oxidant ...
https://insight.jci.org/articles/view/135951
Greater than 95% of clinical cases of AAT deficiency result from low levels of AAT from the Z allele of the SERPINA1 gene (1, 2, 4–6, 23, 26–28) ...
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65 Basics of Alpha-1 | Coram, A CVS Specialty infusion services
https://www.coramhc.com/patients/basics-alpha-1
Medications called augmentation therapies help replace the missing AAT in your blood and lungs. Augmentation therapies don't cure Alpha-1, but they can slow ...
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66 Alpha-1 Antitrypsin Deficiency Treatment - Rare Disease Advisor
https://www.rarediseaseadvisor.com/disease-info-pages/alpha-1-antitrypsin-deficiency-treatment-aatd/
Intravenous augmentation therapy is a specific, AATD-targeted treatment that infuses purified pooled human plasma AAT. This intervention's ...
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67 Alpha1-antitrypsin deficiency - Lung Foundation Australia
https://lungfoundation.com.au/patients-carers/living-with-a-lung-disease/other-lung-conditions/alpha1-antitrypsin-deficiency/
Although there is no current cure for AATD, early diagnosis and treatment of AATD related COPD is important as it enables you to make positive lifestyle changes ...
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68 Alpha-1 Deficiency | Conditions - Penn State Health
https://www.pennstatehealth.org/services-treatments/alpha-1-deficiency
With early diagnosis and proper treatment, many people with Alpha-1 deficiency will not develop lung or liver disease. In severe cases, the condition can ...
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69 Alpha-1 Antitrypsin Deficiency Genetic Testing - Women's Health
https://www.afwomensmed.com/health-library/hw-view.php?DOCHWID=uf6753
Treatment for alpha-1 antitrypsin deficiency involves avoiding substances—especially cigarette smoke—that could harm your lungs. Also try to avoid dust and ...
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70 Alpha-1 Antitrypsin Deficiency and Emphysema
https://myhealth.alberta.ca/Health/aftercareinformation/pages/conditions.aspx?hwid=ud1557
Medicines · Alpha-1 antitrypsin (AAT) replacement (such as Prolastin). This may slow down lung disease in people with AAT deficiency. · Bronchodilators (such as ...
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71 Alpha-1 antitrypsin deficiency targeted testing and ...
https://cts-sct.ca/wp-content/uploads/2018/01/Alpha-1-GUIDELINE-2012.pdf
The evidence also supports consideration of A1AT augmentation therapy in nonsmoking or exsmoking patients with COPD (forced expiratory volume in. 1 s of 25% to ...
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72 Alpha 1 Antitrypsin Deficiency | Children's Liver Disease ...
https://childliverdisease.org/liver-information/childhood-liver-conditions/alpha-1-antitrypsin-deficiency/
Are there any treatments or cures for liver disease associated with alpha-1 antitrypsin deficiency?
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73 COPD and Alpha-1 Antitrypsin (AAT) Deficiency
https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.copd-and-alpha-1-antitrypsin-aat-deficiency.hw164553
Injections of replacement alpha-1 antitrypsin are given either weekly or every 2 to 4 weeks. Benefits of the therapy are not clear at this time. Related ...
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74 What is alpha-1-antitrypsin deficiency?
https://www.asthmafoundation.org.nz/assets/documents/What-is-Alpha-1-Fact-Sheet.pdf
Higher blood concentrations of alpha-1-antitrypsin would hopefully protect lung tissue from destruction. This treatment is still very much in the experimental ...
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75 Developing Alpha-1 Antitrypsin Therapeutics; Public Workshop
https://www.fda.gov/vaccines-blood-biologics/workshops-meetings-conferences-biologics/developing-alpha-1-antitrypsin-therapeutics-public-workshop-09162019-09162019
Symptomatic treatments, including medications called bronchodilators and oxygen, may be given for the lung disease in AAT deficiency, and in ...
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76 Alpha-1 Antitrypsin Deficiency - American Liver Foundation
https://liverfoundation.org/liver-diseases/pediatric-liver-disease/alpha-1-antitrypsin-deficiency/
Currently, there is no cure for Alpha-1. Treatment is designed to maintain normal nutrition, to provide the liver and the body with essential ...
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77 Alpha-1 Antitrypsin Deficiency Medications - GoodRx
https://www.goodrx.com/alpha-1-antitrypsin-deficiency/drugs
ALPHA-1-PROTEINASE INHIBITOR (AL fa - 1 PRO tee nase in HIB i tor) is a drug that is used to replace an enzyme in patients with lung problems caused by low ...
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78 Alpha1-Proteinase Inhibitors - UHCprovider.com
https://www.uhcprovider.com/content/dam/provider/docs/public/policies/comm-medical-drug/alpha1-proteinase-inhibitors.pdf
Alpha1-proteinase inhibitors (Aralast NP™, Glassia™, Prolastin®-C, and Zemaira®) are proven for chronic augmentation and maintenance therapy of ...
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79 Experimental and investigational drugs for the treatment of ...
https://www.tandfonline.com/doi/full/10.1080/13543784.2019.1672656
The standard of care in lung disease due to AATD is alpha-1 antitrypsin augmentation but there are several new and emerging treatment options under ...
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80 Cambridge spin-out doses first subject with treatment for alpha ...
https://www.enterprise.cam.ac.uk/news/cambridge-spin-out-doses-first-subject-with-treatment-for-alpha-1-antitrypsin-deficiency/
Drug development company Z Factor Ltd announced that the first human volunteer was dosed today with ZF874, its novel treatment for alpha-1- ...
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81 Alpha-1 Antitrypsin Deficiency - MedicineNet
https://www.medicinenet.com/life_expectancy_alpha-1_antitrypsin_deficiency/article.htm
How is alpha-1 antitrypsin deficiency treated? · Augmentation or replacement therapy: This involves AAT replacement to increase it to normal levels.
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82 COPD and Alpha-1 Antitrypsin (AAT) Deficiency - Cigna
https://www.cigna.com/knowledge-center/hw/copd-and-alpha-1-antitrypsin-deficiency-hw164553.html
› knowledge-center › copd-and...
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83 Alpha 1-antitrypsin deficiency. Treatment and symptoms | Patient
https://patient.info/doctor/alpha-1-antitrypsin-deficiency-pro
› ... › Professional Articles
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84 Alpha 1 Antitrypsin Deficiency | Children's Hospital Colorado
https://www.childrenscolorado.org/conditions-and-advice/conditions-and-symptoms/conditions/alpha-1-antitrypsin-deficiency/
Learn about the symptoms, diagnosis and treatment of alpha-1 antitrypsin deficiency in infants and children.
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85 Alpha-1 Antitrypsin Deficiency - Vertex Pharmaceuticals
https://www.vrtx.com/our-science/pipeline/alpha-1-antitrypsin-deficiency
There is currently no cure for AATD. There are also no treatments that target the underlying cause of the disease or that address the liver disease associated ...
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86 Alpha-1-Antitrypsin Deficiency - Cancer Therapy Advisor
https://www.cancertherapyadvisor.com/home/decision-support-in-medicine/pediatrics/alpha-1-antitrypsin-deficiency/
If you are able to confirm that the patient has alpha-1-antitrypsin deficiency, what treatment should be initiated? ... There is no specific treatment for a1AT ...
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87 Alpha 1 “Hereditary Emphysema” Experience: A Patient ...
https://link.springer.com/article/10.1007/s41030-020-00119-4
The lung treatment recommendations for patients with A1ATD and COPD are generally the same as COPD without A1ATD. These recommendations include ...
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88 Alpha 1-Proteinase Inhibitors [Medicare] - Aetna
http://www.aetna.com/cpb/medical/data/100_199/0145m.html
Aetna considers alpha 1-proteinase inhibitor (e.g., Aralast NP, Glassia, Prolastin-C, and Zemaira) therapy medically necessary for the treatment of ...
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89 A Review of Alpha-1 Antitrypsin Binding Partners for Immune ...
https://www.mdpi.com/1422-0067/23/5/2441
Weekly treatment doses of AAT higher than the FDA-approved standard dose (60 mg/kg/week) are not currently recommended [167]. Results of a recent pilot study, ...
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90 Alpha-1 Antitrypsin Deficiency (AATD) - Cedars-Sinai
https://www.cedars-sinai.org/health-library/diseases-and-conditions/a/alpha-1-antitrypsin-deficiency-aatd.html
Patients can manage their disease through lifestyle changes, such as quitting smoking, which effectively reduces symptoms. Longterm treatment of A1AD will ...
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91 Without plasma treatment, life turns deeply insecure for Alpha ...
https://www.euractiv.com/section/health-consumers/news/without-plasma-treatment-life-turns-deeply-insercure-for-alpha-1-patients/
As an Alpha-1 Antitrypsin Deficiency (AATD) patient, Frank Willersinn is dependent on a treatment with a plasma-derived medicine (PDMP) to ...
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92 Alpha-1 Center | Boston Medical Center
https://www.bmc.org/alpha-1-center
Our staff is dedicated to caring for all facets of this disease, from prevention to genetic counseling to alpha-1 augmentation therapy.
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93 Definition of alpha-1 antitrypsin deficiency - NCI Dictionary of ...
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/alpha-1-antitrypsin-deficiency
NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.
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94 Alpha-1 Antitrypsin Deficiency: How to Spot and Treat It
https://healthtalk.unchealthcare.org/alpha-1-antitrypsin-deficiency-how-to-spot-and-treat-it/
Augmentation therapy, also called replacement therapy, is available to patients with two abnormal alpha-1 genes who are experiencing severe lung ...
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95 Alpha-1 Antitrypsin Deficiency - Learn Genetics Utah
https://learn.genetics.utah.edu/content/genetics/alpha1/
Treating and managing Alpha-1 · Limit tobacco smoke and air pollution. Lung irritants cause inflammation (and increase levels of neutrophil elastase) and block ...
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96 Alpha-1 Antitrypsin Deficiency - Accredo
https://www.accredo.com/conditions/alpha-1
Emphysema (diagnosed at age 45 or earlier); Liver disease with no known cause; Bronchiectasis (in adults); Asthma that does not respond to traditional treatment ...
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97 Alpha-1-antitrypsin deficiency panniculitis - DermNet
https://dermnetnz.org/topics/alpha-1-antitrypsin-deficiency-panniculitis
Systemic corticosteroids, antimalarials, immunosuppressants and danazol are ineffective in alpha-1-antitrypsin deficiency disease. Enzyme replacement therapy.
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