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1 Conceptual aspects of self and nonself discrimination - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136900/
Innate immunity not only recognizes nonself antigens, but also utilizes more sophisticated mechanisms of recognition. Modification of self proteins by microbial ...
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2 Self versus Non-Self | BioNinja
http://ib.bioninja.com.au/higher-level/topic-11-animal-physiology/111-antibody-production-and/self-versus-non-self.html
The immune system has the capacity to distinguish between body cells ('self') and foreign materials ('non-self'). It will react to the presence of foreign ...
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3 Decoding the Patterns of Self and Nonself by the Innate ...
https://www.science.org/doi/10.1126/science.1068883
The innate immune system evolved several strategies of self/nonself discrimination that are based on the recognition of molecular patterns demarcating ...
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4 How does the immune system distinguish self from nonself?
https://www.sciencedirect.com/science/article/pii/S1044532300902306/pdf?md5=82038d87ae8df4e8e14ccd69ccfbfcf5&pid=1-s2.0-S1044532300902306-main.pdf
The immune system accomplishes self–nonself discrimination, in part, by employing cell‐surface recognition molecules which, when activated by nonself ligands ...
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5 Your Immune System: The Basics - Breastcancer.org
https://www.breastcancer.org/managing-life/immune-system/basics
All of your body's cells carry specific proteins on their surfaces that help the immune system recognize them as “self.” That's why the immune ...
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6 Immune system physiology | NCLEX-RN | Khan Academy
https://www.youtube.com/watch?v=afM6_VFaIss
khanacademymedicine
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7 An introduction to immunology and immunopathology
https://aacijournal.biomedcentral.com/articles/10.1186/s13223-018-0278-1
The primary functions of the adaptive immune response are: the recognition of specific “non-self” antigens, distinguishing them from “self” ...
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8 Self-Tolerance - GenScript
https://www.genscript.com/self-tolerance.html
Self-tolerance is the ability of the immune system to recognize self-produced antigens as a non-threat while appropriately mounting a response to foreign ...
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9 How the immune system works to protect the host from infection
https://www.pnas.org/doi/10.1073/pnas.131202998
The self-referential nature of adaptive immunity, which is based on antigen-specific responses of T and B lymphocytes, is now well established for T cells, and, ...
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10 What Happens When the Immune System Does Not Work ...
https://www.chop.edu/centers-programs/vaccine-education-center/human-immune-system/what-happens-when-immune-system-does-not-work-properly
Sometimes the immune system does not work properly due to immune deficiencies ... immune responses, such as allergies; or immune responses to one's self, ...
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11 The Immune System Computes the State of the Body - Frontiers
https://www.frontiersin.org/articles/10.3389/fimmu.2019.00010/full
Immune system decisions are primed by formative experience with training sets of self-antigens encountered during lymphocyte development; these ...
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12 How the Immune System Recognizes Self and Nonself
https://link.springer.com/book/10.1007/978-4-431-73884-8
The immune system recognizes and distinguishes a variety of structural features of self and nonself components. The latter actually include almost everything ...
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13 In Defense of Self: How the Immune System Really Works
https://www.amazon.com/Defense-Self-Immune-System-Really/dp/0195335554
In Defense of Self: How the Immune System Really Works: 9780195335552: Medicine & Health Science Books @ Amazon.com.
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14 Recognition Of Self Vs Non Self Autoimmune Diseases
https://jackwestin.com/resources/mcat-content/immune-system/recognition-of-self-vs-non-self-autoimmune-diseases
The lymphocytes of the immune system form antibodies to fight non-self antigens. Sometimes, the lymphocytes create antibodies for self-antigens known as ...
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15 Immune recognition of self and non-self explored in new study
https://news.asu.edu/20220601-discoveries-immune-recognition-self-and-nonself-explored-new-asu-biodesign-study
In a new study, ASU researcher Joshua LaBaer and his colleagues explore components of the immune system known as autoantibodies.
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16 Chapter 15 Self and Nonself - Lehigh University
https://www.lehigh.edu/~mhb0/PhilBioPotentialReadings%2020Oct18/Sahotra_Sarkar,_Anya_PlutynskiSelfNonself_A_Companion_to_th%20.pdf
Because of adaptive immunity, self–nonself discrimination in jawed vertebrates is specialized and precise: vertebrate immune systems are fine-tuned to ...
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17 The Immune System and Primary Immunodeficiency
https://primaryimmune.org/immune-system-and-primary-immunodeficiency
The immune system is composed of a variety of different cell types and proteins. ... their own cells or tissues as if these cells were foreign, or non-self.
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18 Self recognition by the immune system
https://febs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1432-1033.1990.tb19459.x
In each organism, the immune system must acquire the ability to distinguish self from nonself. Experiments in T cell receptor transgenic mice indicate that this ...
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19 The Innate vs. Adaptive Immune Response - Healio
https://www.healio.com/hematology-oncology/learn-immuno-oncology/the-immune-system/the-innate-vs-adaptive-immune-response
The second line of defense against non-self pathogens is called adaptive immune response. Adaptive immunity is also referred to as acquired immunity or specific ...
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20 Self and Non-self Discrimination of Intracellular Membranes ...
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1003538
Figures · Overview · The Innate Immune System Recognizes and “Marks” Pathogen-Containing Vacuolar Membranes and Cytosolic Bacteria for Autophagic ...
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21 Types of Antigens | Non-Self Antigens, Self-Antigens & Allergens
https://study.com/academy/lesson/non-self-antigens-self-antigens-allergens.html
The antigen-presenting cells will only present non-self antigens to the adaptive immune system cells that will stimulate an aggressive immune ...
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22 The Main Principles of Adaptive Immune System Function ...
https://www.eurekaselect.com/chapter/5203
The main forms of physiological activity of the immune system are based on the intrinsic abilities of self-identification, selfmaintenance, self-regulation, ...
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23 Understanding the Immune System - SITC connectED
https://www.sitcancer.org/connectedold/p/patient/resources/melanoma-guide/immune-system
Cells with self-antigens are typically not a threat. Invading germs, however, do not originate in the body and so do not carry self-antigens; instead, they ...
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24 What is Immune Tolerance & Types of Immunological Tolerance
https://www.akadeum.com/blog/what-is-immune-tolerance/
Self-tolerance refers to the ability of the immune system to recognize—and therefore not respond against—self-produced antigens. If the immune system loses ...
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25 How the immune system achieves self ... - Semantic Scholar
https://www.semanticscholar.org/paper/How-the-immune-system-achieves-self-nonself-during-Jiang-Chess/ca53982fc2583e32573db5e185971b6c9989f6c2
Semantic Scholar extracted view of "How the immune system achieves self-nonself discrimination during adaptive immunity." by Hong Jiang et al.
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26 Immunology: How Does the Adaptive Immune System Work?
https://blog.cellsignal.com/immunology-how-does-the-adaptive-immune-system-work
The adaptive immune response uses antigen-specific receptors to detect foreign ... critical jobs of the immune system is to distinguish self from non-self.
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27 Why Your Immune System Doesn't Eat You Alive
https://www.scientificamerican.com/article/why-your-immune-system-doesn-t-eat-you-alive/
As a solution, some scientists proposed that the body wipes out those self-reactive cells while the immune system is developing. Subsequent ...
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28 The immune system and immunisation
https://www.immune.org.nz/immunisation/immune-system-vaccination
Each pathogen has unique distinguishing components, known as antigens, which enable the immune system to differentiate between 'self' (the body) and 'non-self' ...
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29 Immune system - Wikipedia
https://en.wikipedia.org/wiki/Immune_system
The immune system is a network of biological processes that protects an organism from diseases. It detects and responds to a wide variety of pathogens, ...
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30 How does the immune system self-regulate? - BioTechniques
https://www.biotechniques.com/immunology/how-does-the-immune-system-self-regulate/
How does the immune system self-regulate? · Regulatory T cells control the immune reaction from killer cells to ensure healthy tissue surrounding ...
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31 Autoimmune Disease: Why Is My Immune System Attacking ...
https://www.hopkinsmedicine.org/health/wellness-and-prevention/autoimmune-disease-why-is-my-immune-system-attacking-itself
When the body senses danger from a virus or infection, the immune system kicks into gear and attacks it. This is called an immune response. Sometimes, healthy ...
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32 20.2: Introduction to the Immune System - Biology LibreTexts
https://bio.libretexts.org/Bookshelves/Human_Biology/Book%3A_Human_Biology_(Wakim_and_Grewal)/20%3A_Immune_System/20.2%3A_Introduction_to_the_Immune_System
Host vs. Pathogen · What is the Immune System? · Self vs. Non-Self · Antigens and Antibodies · Immune Surveillance · Lymphatic System · Review.
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33 What is Immune Tolerance? - Anokion
https://anokion.com/science-platform/what-is-immune-tolerance/
A healthy immune system targets only foreign antigens, not the body's own cells (self-antigens). The immune system's recognition of self-antigens is called ...
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34 How Do Antibodies Work? | In Defense of Self
https://academic.oup.com/book/3855/chapter/145385034
Innate and adaptive immunity should not be thought of as two separate immune systems. They are part of a single, coordinated response we mount against microbial ...
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35 Discriminating self from non-self in nucleic acid sensing - Nature
https://www.nature.com/articles/nri.2016.78
The detection of viruses by the immune system is mediated predominantly by the sensing of nucleic acids. Here, the authors review our ...
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36 Does the Immune System Act as a Self-Organized System in ...
https://neuro.psychiatryonline.org/doi/10.1176/appi.neuropsych.12060150
Does the Immune System Act as a Self-Organized System in Multiple Sclerosis? · Bahareh Safarbali, M.Sc. student , · Fatemeh Hadaeghi, Ph.D.
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37 23.2. Adaptive Immune Response – Concepts of Biology
https://opentextbc.ca/biology/chapter/23-2-adaptive-immune-response/
An antigen is a foreign or “non-self” macromolecule that reacts with cells of the immune system. Not all antigens will provoke a response.
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38 What is an Antigen? - News Medical
https://www.news-medical.net/life-sciences/What-is-an-Antigen.aspx
Any substance that induces the immune system to produce antibodies against it ... Autoantigens or self-antigens are normal cellular proteins or a complex of ...
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39 How Lupus Affects the Immune System
https://www.hopkinslupus.org/lupus-info/lupus-affects-body/lupus-immune-system/
In lupus, the immune system begins to recognize and attack “self.” In other words, the cells of the immune system begin to injure the body's own tissues.
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40 Antigen: What It Is, Function, Types, & Testing - Cleveland Clinic
https://my.clevelandclinic.org/health/diseases/24067-antigen
They tell your immune system that they are either friendly (“self”) or harmful. These include cells that are infected with bacteria or a virus ...
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41 Three Important Characteristics to Adaptive Immunity
https://www.dentalcare.com/en-us/ce-courses/ce1/three-important-characteristics-to-adaptive-immunity
This property refers to the ability of the immune system to recognize non-self antigens and respond in a specific manner to them, rather than responding in ...
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42 Understanding the Immune System: How it works - IMGT
https://www.imgt.org/IMGTeducation/Tutorials/ImmuneSystem/UK/the_immune_system.pdf
Contents. 1 Introduction. 2 Self and Nonself. 3 The Structure of the Immune System. 7 Immune Cells and Their Products. 19 Mounting an Immune Response.
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43 How the Innate Immune System Senses Trouble and Causes ...
https://cjasn.asnjournals.org/content/10/8/1459
The innate immune system is the first line of defense against infection (nonself) or tissue injury (damaged self). The cells and molecules ...
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44 Innate vs Adaptive Immunity - Technology Networks
https://www.technologynetworks.com/immunology/articles/innate-vs-adaptive-immunity-335116
How does the immune system tell self from non-self? In humans, all nucleated cells express distinctive surface molecules called major ...
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45 Boot Camp for the Immune System | Harvard Medical School
https://hms.harvard.edu/news/boot-camp-immune-system
To perform its myriad functions, the immune system must, above all, differentiate between self and non-self—a remarkable selective ability ...
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46 T cells, B cells and the immune system
https://www.mdanderson.org/cancerwise/t-cells--b-cells-and-the-immune-system.h00-159465579.html
It generally recognizes patterns in cells that help sort self from pathogens. For example, when an innate immune cell comes into contact with a ...
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47 Immune System (for Parents) - Nemours KidsHealth
https://kidshealth.org/en/parents/immune.html
How Does the Immune System Work? · Innate immunity: Everyone is born with innate (or natural) immunity, a type of general protection. · Adaptive immunity: ...
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48 The Immune System Click & Learn Educator Materials
https://www.biointeractive.org/sites/default/files/media/file/2022-03/ImmuneSystem-Educator-CL.pdf
What type of condition may be caused by T cells that bind to self-antigens? An autoimmune disease (such as rheumatoid arthritis). 2. How does the body replace ...
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49 Immune recognition of self in immunity against cancer
https://www.jci.org/articles/view/22685/version/1/pdf/render.pdf
A new study describes how tumors can avoid recognition by the immune system and how enhancing the affinity of the interaction between a self antigen and the ...
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50 Immune response: MedlinePlus Medical Encyclopedia
https://medlineplus.gov/ency/article/000821.htm
Your immune system learns to see these antigens as normal and usually does not react against them. INNATE IMMUNITY. Innate, or nonspecific, ...
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51 immune system disorder - Autoimmune disorders | Britannica
https://www.britannica.com/science/immune-system-disorder/Autoimmune-disorders
Nevertheless, an immune response to self, called autoimmunity, can occur, and some of the ways that self-directed immune responses cause damage have been ...
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52 The immune system: Cells, tissues, function, and disease
https://www.medicalnewstoday.com/articles/320101
The immune system defends the body from invaders such as viruses, bacteria, and foreign bodies. Find out how it works, what can go wrong, and how to boost ...
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53 The immune system and cancer | EdCaN
https://www.edcan.org.au/edcan-learning-resources/supporting-resources/biology-of-cancer/defining-cancer/immune-system
The immune system has several functions such as defense against foreign organisms, ... These abnormal tumour proteins mark cancer cells as 'non-self'.
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54 Adaptive immune system - Knowledge @ AMBOSS
https://www.amboss.com/us/knowledge/Adaptive_immune_system/
Adaptive (acquired) immunity is a part of the immune system that provides an antigen-specific response following exposure to a microbial ...
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55 Does the Immune System See Tumors as Foreign or Self?
https://www.annualreviews.org/doi/abs/10.1146/annurev.immunol.21.120601.141135
A central question in cancer immunology is whether recognition of tumor antigens by the immune system leads to activation (i.e., surveillance) or tolerance.
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56 Problem 11. Lack of an immune response to self
http://www.biology.arizona.edu/immunology/tutorials/immunology/11q.html
Introduction to Immunology. Problem 11. Lack of an immune response to self. The lack of an immune response to self is called: A. Autoimmunity. B. Tolerance ...
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57 People Who Are Immunocompromised - CDC
https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/people-who-are-immunocompromised.html
Learn about how to protect yourself from COVID-19 if you are ... Some people who are immunocompromised (have a weakened immune system) are more likely to ...
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58 3 Ways to Boost Your Immune System with Self-Massage
https://chopra.com/articles/3-ways-to-boost-your-immune-system-with-self-massage
It also triggers measurable changes in the body's immune and endocrine systems. One 2019 study, by a The Massage Centre, concluded that a ...
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59 How the immune system protects against infection - Inivos
https://inivos.com/blog/how-the-immune-system-protects-against-infection/
In order to destroy invading pathogens and protect us from infection, the immune system has to be able to differentiate between self antigens, ...
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60 The immune system | Essays in Biochemistry - Portland Press
https://portlandpress.com/essaysbiochem/article/60/3/275/78223/The-immune-system
A second sophisticated system, which recognizes and ignores 'self', attacks antigens that it does not know (adaptive immunity). By using a ...
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61 The Immune Response: A Cellular War | Let's Talk Science
https://letstalkscience.ca/educational-resources/stem-in-context/immune-response-a-cellular-war
These are diseases where your body's immune system mistakes self cells for non-self cells. So, the body of someone with an autoimmune disease ...
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62 Does Self-Esteem Function as an Emotional Immune System?
https://www.psychologytoday.com/us/blog/the-squeaky-wheel/201306/does-self-esteem-function-emotional-immune-system
The answer is—yes! Researchers have found that boosting our self-esteem can indeed strengthen our emotional immune systems. Self-esteem ...
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63 What Is the Immune System? - Diabetes Education Online
https://dtc.ucsf.edu/types-of-diabetes/type1/understanding-type-1-diabetes/autoimmunity/what-is-the-immune-system/
Additionally, the immune response allows some foreign material and normal cells for each individual (or “self”) to be tolerated. The balance between a ...
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64 Immune System | Biology for Majors II - Lumen Learning
https://courses.lumenlearning.com/wm-biology2/chapter/immune-system/
Our immune systems offer us protection against a world full of pathogens. ... The presentation of non-self cells can then trigger the immune system.
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65 Immunologic Tolerance and Autoimmunity: Self–Nonself ...
https://basicmedicalkey.com/immunologic-tolerance-and-autoimmunity-self-nonself-discrimination-in-the-immune-system-and-its-failure/
One of the remarkable properties of the normal immune system is that it can react to an enormous variety of microbes but does not react ...
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66 Immune System for the MCAT: Everything You Need to Know
https://www.shemmassianconsulting.com/blog/immune-system-mcat
Learn key MCAT concepts about the immune system, plus practice questions and answers. ... c) Recognition of self and non-self ...
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67 Course #38431: Pathophysiology: The Immune System - NetCE
https://www.netce.com/studypoints.php?courseid=2470&printable=yes&page=printquestions
Self-Assessment Questions. 1 . Immunity can be defined as. A), the invasion and multiplication of micro-organisms.
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68 10 Self-Care Tips for Your Immune and Emotional Health
https://allreddentistry.com/10-self-care-tips-for-your-immune-and-emotional-health/
Stress can hinder your immune system, so if you're not quite able to go back to work yet, you can lower your stress levels by keeping your mind ...
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69 Skin immune system | DermNet
https://dermnetnz.org/topics/skin-immune-system
Macrophages are phagocytic cells that can discriminate between the body's cells (self) and foreign molecules. After phagocytosis by macrophages, an invading ...
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70 Antigen Delivery to Antigen-Presenting Cells for Adaptive ...
https://pubs.acs.org/doi/10.1021/acs.biomac.9b01351
... vaccine that directs the patient's immune system to directly f... ... Cells for Adaptive Immune Response by Self-Assembled Anionic ...
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71 Introductory Chapter: Immune System Dysfunction and ...
https://www.intechopen.com/chapters/54266
Immune system: self- and non–self-discrimination. The essential functions of the immune system is to maintain the coherence of the cells and ...
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72 The immune system explained - Curious
https://www.science.org.au/curious/video/immune-system-explained
› curious › video › immune-s...
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73 The adaptation model of immunity | Immunotherapy
https://www.futuremedicine.com/doi/10.2217/imt.13.157
Although 'self–nonself' and 'danger' theories have improved our understanding of the immune system, successful immunotherapy of cancer and ...
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74 Self-Recognition and Symmetry in the Immune System | 2
https://www.taylorfrancis.com/chapters/edit/10.1201/9780429282324-2/self-recognition-symmetry-immune-system-yaakov-naparstek-robert-schwartz
The diversity of the repertoire of the immune system is immense. There are very few classes of molecules, natural or synthetic, which fail to elicit an.
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75 Vive la difference! Self/non-self recognition and the evolution ...
https://royalsocietypublishing.org/doi/10.1098/rstb.2018.0206
As in brood parasites and their hosts, the adaptive immune system of vertebrates is in an evolutionary arms race with parasites; ...
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76 The Immune System - CancerQuest
https://www.cancerquest.org/cancer-biology/immune-system
, viruses or other organisms that can invade our bodies. A more subtle distinction between self and non-self occurs in the recognition of cancer cells by the ...
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77 The Immune System
https://www.aber.ac.uk/~dcswww/ISYS/immune_system.html
The immune system is a complex network of organs containing cells that ... is an autoimmune (literally "self-immune") disease in which the immune system ...
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78 How Does the Immune System Work 101 - Immuse
https://immusehealth.com/what-is-immuse-lc-plasma/immune-system-101
That said, a range of immune cells constantly patrol the body in search of anything not recognized as self. When they encounter a stimuli that doesn't belong in ...
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79 Immune System Anatomy - Medscape Reference
https://emedicine.medscape.com/article/1948753-overview
The immune system is an inherent self-defense system consisting of cells that helps the body distinguish between self and non-self molecules ...
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80 Host, heal thyself: Immune system self-organizes to minimize ...
https://medicalxpress.com/news/2015-05-host-thyself-immune-self-organizes-minimize.html
Host, heal thyself: Immune system self-organizes to minimize biological cost of pathogenic infections. by Stuart Mason Dambrot , Medical Xpress.
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81 Self-hypnosis boosts immune system: Trends in Immunology
https://www.cell.com/trends/immunology/fulltext/S1471-4906(01)02136-6
... have now reported that the stress-relieving technique of self-hypnosis can help to protect against the adverse effects of stress on the immune system.
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82 The Immune System
https://www.cirm.ca.gov/sites/default/files/files/about_stemcells/Unit_4_Lesson.ppt
Brainstorm; Basic organization and function of the immune system ... fail because there isn't a match, and lymphocytes destroy the non-self cells. Immune ...
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83 Definition of Autoimmunity & Autoimmune Disease
https://pathology.jhu.edu/autoimmune/definitions
These components are called autoantigens or self-antigens and typically consist of ... Cancer patients who are treated with inhibitors of immune checkpoints ...
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84 Chapter 2 How the Immune System Achieves ... - ResearchGate
https://www.researchgate.net/publication/26248534_Chapter_2_How_the_Immune_System_Achieves_Self-Nonself_Discrimination_During_Adaptive_Immunity
... The immune system's capacity to discriminate between self and non-self is based on the high specificity poised by immune cells. The immune ...
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85 What are lymphocytes? A guide to your immune system - CC
https://blog.cambridgecoaching.com/what-is-a-lymphocyte-immune-cell
T lymphocytes must travel to the thymus to mature. It is here that they are taught to recognize self (our own cells/antigens) from non-self (viruses, bacteria ...
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86 Overview of Immunity - SPH - Boston University
https://sphweb.bumc.bu.edu/otlt/mph-modules/ph/ph709_defenses/ph709_defenses3.html
By distinguishing between "self" and "non-self" these systems are ... The innate immune system has certain "sentinel cells (monocytes, ...
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87 Immune system Definition and Examples - Learn Biology Online
https://www.biologyonline.com/dictionary/immune-system
It is the organ system that detects and distinguishes the self from non-self. Immune cells, such as the white blood cells, produce an immune ...
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88 Long COVID: Researchers Zero in on Self-Targeted Immune ...
https://www.clinicaladvisor.com/home/topics/infectious-diseases-information-center/long-covid-how-researchers-are-zeroing-in-on-the-self-targeted-immune-attacks-that-may-lurk-behind-it/
The immune system, even in its healthy state, contains a contingent of cells that are fully capable of targeting and destroying cells and ...
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89 Control of Immune Responses by Naturally Arising CD4 + ...
https://rupress.org/jem/article/197/4/397/8439/Control-of-Immune-Responses-by-Naturally-Arising
It is a key issue in immunology to understand how the immune system discriminates between self- and nonself, inhibiting autoimmune responses but allowing ...
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90 Study links severe COVID-19 to increase in self-attacking ...
https://med.stanford.edu/news/all-news/2021/09/covid-19-autoantibodies.html
In some cases, the presence of those newly detected autoantibodies may reflect an increase, driven by the immune response, of antibodies that ...
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91 The Biology of the Immune Response - JAMA Network
https://jamanetwork.com/journals/jama/fullarticle/401411
THE IMMUNE system is composed of a large and complex set of ... against foreign pathogens while not responding adversely to self-components.
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92 Drugs give the immune system a mistaken sense of self
https://arstechnica.com/science/2012/05/drugs-give-the-immune-system-a-mistaken-sense-of-self/
Researchers identify how some small molecules can set off an immune response.
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93 Show Your Immune System Some Love - The Atlantic
https://www.theatlantic.com/science/archive/2021/04/antibody-breakup/618668/
And in many cases, innate immune cells act so quickly and decisively that they can subdue an invasive microbe on their own—a level of self- ...
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94 6 Ways to Boost Your Immune System - Houston Methodist
https://www.houstonmethodist.org/blog/articles/2020/mar/5-ways-to-boost-your-immune-system/
But supporting a healthy immune system is more complicated than taking a ... isn't just for building muscles and helping yourself de-stress ...
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