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1 K/BxN Serum-Transfer Arthritis as a Model for Human ... - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889615/
This unit describes detailed methods for the maintenance of a K/BxN colony, induction of arthritis by serum transfer, clinical evaluation of arthritis, and ...
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2 Disease severity in K/BxN serum transfer-induced arthritis is ...
https://arthritis-research.biomedcentral.com/articles/10.1186/ar4143
Our results show that Fc-μTP-L309C is a powerful treatment for the prevention and amelioration of severe, chronic arthritis in a true autoimmune ...
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3 K/B×N serum transfer arthritis is delayed and less severe in ...
https://academic.oup.com/cei/article/169/2/71/6438596
K/B×N serum, leukaemia inhibitory factor, mice arthritis model. Issue Section: ... Among the animal models of arthritis, the K/B×N serum transfer model is a ...
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4 Neuraminidase Inhibitor Zanamivir Ameliorates Collagen ...
https://www.mdpi.com/1422-0067/22/3/1428/htm
CIA, a commonly used model of RA, can be induced in susceptible mouse strains [29 ... Arthritis was induced at day 0 in C57BL/6J mice by KBN serum transfer.
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5 Antibody-induced arthritis: disease mechanisms and genes ...
https://europepmc.org/article/med/17254316
These new antibody mediated arthritis models have proven to be very useful for ... The development of arthritis in the KBN mice, but not the anti-G6PI ...
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6 A crucial role for macrophages in the pathology of K/B × N ...
https://onlinelibrary.wiley.com/doi/10.1002/eji.200526167
This has been well documented in the anti-collagen II antibody-induced arthritis animal model for a long time now. Recently, in the K/B × N ...
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7 Arthritis models: usefulness and interpretation | Scholars Portal ...
https://journals.scholarsportal.info/details/18632297/v39i0004/469_amuai.xml
Animal models of arthritis are used to better understand pathophysiology of a ... different types of collagen-induced arthritis and arthritis in KBN mice.
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8 Arthritis models: usefulness and interpretation - ProQuest
https://search.proquest.com/openview/8d3ffecacbd33bba2330c46b1758caa6/1?pq-origsite=gscholar&cbl=39687
The most popular models are the different types of collagen-induced arthritis and arthritis in KBN mice. As spontaneous arthritides, human TNF-[alpha] ...
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9 Inhibition of Glycolysis Reduces Disease Severity in an ...
https://www.readcube.com/articles/10.3389/fimmu.2018.01973
It is a model of autoimmune seropositive arthritis because the production of anti-GPI IgG is ... The KBN mouse is a spontaneous model of arthritis driven
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10 Inhibition of Glycolysis Reduces Disease Severity in ... - CORE
https://core.ac.uk/download/pdf/228989031.pdf
in an Autoimmune Model of Rheumatoid Arthritis. Georges Abboud. Seung-Chul Choi ... The KBN mouse is a spontaneous model of arthritis driven.
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11 Glycolysis inhibition reduced joint inflammation in KBN mice ...
https://www.researchgate.net/figure/Glycolysis-inhibition-reduced-joint-inflammation-in-KBN-mice-Time-course-of-joint_fig2_327410718
Joint thickness in KRN mice after transfer of serum from KBN mice treated with 2DG ... The K/BxN mouse is a spontaneous model of arthritis driven by T cell ...
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12 Essential role of microRNA-155 in the ... - Faculty Opinions
https://facultyopinions.com/article/9329958
Then, they tested another model of spontaneous erosive arthritis, the K/BxN serum ... Upon injection of KBN serum into miR-155-/- mice and WT controls, ...
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13 Spontaneous Arthritis Models - Creative Bioarray
https://www.creative-bioarray.com/services/spontaneous-arthritis-models.htm
Figure. 1. Glycolysis inhibition reduced joint inflammation in KBN mice. Time course of joint thickness (A) and clinical scores (B) in mice treated or not with ...
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14 Arthritis models: usefulness and interpretation. - ebsco
http://search.ebscohost.com/login.aspx?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=18632297&AN=123716634&h=R5vrkRgqRcbgkDu8mMqwk6jddSWlAD9d9dj5WIUrcD0J9OXlXcGkIyRdYZ4IPD9jwNzQscbA5gjGDU0pkvqPXQ%3D%3D&crl=c
The most popular models are the different types of collagen-induced arthritis and arthritis in KBN mice. As spontaneous arthritides, human TNF-α transgenic ...
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15 Targeting IgG in Arthritis: Disease Pathways and Therapeutic ...
https://pdfs.semanticscholar.org/bc4a/036a75b1bac0bd15a0ea088566001dfa462e.pdf
Similar to CAIA, arthritis caused by KBN serum transfer is MHC independent. ... In this model, FcγRIII is required for inflammation and.
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16 Results 47 4.1.10. Modeling of epitope residues on the GPI ...
https://kops.uni-konstanz.de/bitstream/handle/123456789/8618/Solomon06.pdf?sequence=2&isAllowed=y
4.2 Role of Innate immunity mediators in KBN Rheumatoid Arthritis mice model. 4.2.1. KBN Sera transfer induced RA in laboratory mice strains BALB/C mice are ...
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17 Autoantibodies as Diagnostic Markers and Mediator of Joint ...
https://www.hindawi.com/journals/mi/2019/6363086/
Rheumatoid arthritis is a systemic, polygenic, and multifactorial syndrome ... In a T cell receptor transgenic (KBN) mouse model, continuous production of ...
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18 Molecules and Cells - AJOU Open Repository
http://repository.ajou.ac.kr/bitstream/201003/1123/3/18319615.pdf
role protecting the arthritic mice from systemic expan- ... of a proteoglycan-induced arthritis model concluded that ... (KBN S) mice for 72 h.
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19 Inhibition of Glycolysis Reduces Disease Severity in an ... - Gale
https://go.gale.com/ps/i.do?id=GALE%7CA552795226&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=16643224&p=AONE&sw=w
It is a model of autoimmune seropositive arthritis because the production of ... B cells from KBN mice are more metabolically active than the KRN controls.
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20 Therapeutic senescence via GPCR activation in synovial ...
https://www.nature.com/articles/s41467-020-14421-x
In vivo, activation of MC1 leads to anti-arthritic effects associated ... the reversion of fibrosis in a mouse model of liver cirrhosis.
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21 The Involvement of V, 14 Natural Killer T Cells in the
https://mhlw-grants.niph.go.jp/system/files/2005/057131/200500774A/200500774A0005.pdf
Pathogenesis of Arthritis in Murine Models ... induced arthritis (CLA) model. ... Rcduced severity of arthritis induced by transfer of KBN.
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22 The cation channel Trpv2 is a new suppressor of arthritis ...
https://academicworks.medicine.hofstra.edu/cgi/viewcontent.cgi?article=3905&context=articles
correlate with radiographic and histologic damage in RA [6] and in animal models of arthritis such as pristane-induced arthritis (PIA) [7].
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23 UvA-DARE (Digital Academic Repository)
https://pure.uva.nl/ws/files/2220339/151105_09.pdf
osteoclastogenesis in RA patients and in mouse models of RA. ... after KBN serum transfer arthritis model (WT, n=4; Flt3L−/−, n=4).
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24 A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED
https://clinicaltrials.gov/ProvidedDocs/19/NCT03001219/Prot_SAP_000.pdf
RHEUMATOID ARTHRITIS AND AN INADEQUATE RESPONSE TO. TNF-α INHIBITORS ... rheumatoid arthritis involving synovitis (the KBN model).
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25 Animal Models of T Cell-Mediated Skin Diseases
https://books.google.com/books?id=wdlgntP-8l8C&pg=PA186&lpg=PA186&dq=kbn+arthritis+model&source=bl&ots=5Eo94ouXoW&sig=ACfU3U3gnGbmn12qLp09xiHdgbSvLPhLpw&hl=en&sa=X&ved=2ahUKEwjql6CmzNT7AhXFi_0HHXUZDe0Q6AF6BQjaARAD
9.5.5 Rheumatoid Arthritis Rheumatoid arthritis (RA) is a chronic inflammatory ... In the K/BxNOD (KBN) arthritis model, plasma cells play a crucial role ...
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26 gpr40 expression and function in immune cells ... - QMRO Home
https://qmro.qmul.ac.uk/xmlui/bitstream/handle/123456789/25975/Soares%20de%20Souza_P_PhD_final_150617.pdf?sequence=1
KBN-serum induced arthritic mice developed a more severe disease ... Table 1: Main characteristics of some models of arthritis .
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27 Oxidative modification of type II collagen differentially affects ...
http://surfer.iitd.pan.wroc.pl/files/AITEFullText/5917.pdf
(KBN, Poland) and by grant no. ... model for autoimmune arthritis that resembles ... severity of arthritis is highest after immunization with.
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28 Pregnancy and early onset pauciarticular juvenile chronic ...
https://ard.bmj.com/content/58/8/475
Pregnancy and early onset pauciarticular juvenile chronic arthritis ... postpartum flare in an experimental model of collagen induced arthritis.19 ,20 Thus, ...
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29 US20110045003A1 - Cadherin-11 antagonists and methods for the ...
https://patents.google.com/patent/US20110045003A1/en
32 is a graph depicting inhibition of joint swelling in a KBN mouse model of arthritis following administration of H1M1 antibodies relative to control.
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30 Hsp40 proteins modulate humoral and cellular immune - JSTOR
https://www.jstor.org/stable/20799952
and human Hsp40s in patients with rheumatoid arthritis ... bacterial Hsp proteins and the model representative of the. Hsp40 family. In the full-length E.
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31 CONTEMPORARY PEDIATRICS - CECentral
http://www.cecentral.com/assets/2172/Brochure_FINAL.pdf
The Kentucky Board of Nursing (KBN) approves the University of Kentucky. College of Nursing as a provider as well. ANCC and KBN approval of ...
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32 Copper levels in patients with rheumatoid arthritis
https://www.aaem.pl/pdf-71934-9161?filename=Copper%20levels%20in%20patients.pdf
Rheumatoid arthritis (RA) is a chronic, autoimmune-based disease of the connective tissue with still ... was conducted under KBN (Polish Scientific Research.
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33 DESCRIPTION AND PURPOSE OF THE
https://chfs.ky.gov/agencies/dph/dpqi/hcab/Documents/GeneralInformation.doc
Arthritis Foundation, www.arthritis.org ... KY Board of Nursing, www.kbn.ky.gov ... KBN Advisory Opinion Statement #14 - Roles of Nurses in Implementing ...
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34 Inflammation, the Key to Much Pathology - Journals on the Web
https://jow-prodeu.cortellis.int.clarivate.com/journals/servlet/xmlxsl/pk_journals.xml_article_pr?p_JournalId=3&p_RefId=2855&p_IsPs=Y&p_ispdf=N
Using a mouse model of chronic allergic asthma, Dr. Paul Foster (Department ... resistant to developing rheumatoid arthritis in response to KBN or collagen.
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35 Humanized antibodies targeting the EC1 domain of Cadherin-11 ...
https://www.freepatentsonline.com/8940300.html
32 is a graph depicting inhibition of joint swelling in a KBN mouse model of arthritis following administration of H1M1 antibodies relative to control.
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36 Humanized Antibodies Targeting the EC1 Domain of ...
https://www.google.com.af/patents/US20150132305
32 is a graph depicting inhibition of joint swelling in a KBN mouse model of arthritis following administration of H1M1 antibodies relative to control.
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37 LysMD3 is a type II membrane protein without an in vivo role ...
https://www.jbc.org/article/S0021-9258(20)40952-4/pdf
pendent KRN model of serum-induced arthritis (34, 35). ... Mice were i.v. injected with KBN serum at day 0 and monitored for weight loss.
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38 Understanding IVIg to Rationally Design Novel Therapeutics
https://s24.q4cdn.com/902352448/files/doc_downloads/2-presentation_PEGS-Boston-May-5-2014-Manning_IVIg.pdf
Sialylated IVIg Suppresses Arthritis in the K/BxN. Serum Transfer Model of Arthritis ... MNT-KBN-004 Total Delta.
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39 Orthotics - Stanislaus - Trilogy Integrated Resources
https://stanislaus.networkofcare.org/veterans/assistive/list.aspx?cid=241
The Hand Gym Exercise Unit Designed for people with arthritis, ... The Sacro Ease Keri Back Cushion, models KBT and KBN, is a back support cushion designed ...
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40 Outcome status - KBN PORTAL
http://www.kbn.re.kr/status/result.do;jsessionid=A7596402FCF4F292A461859D75A25EAF?menuNm=thesis&type=04&lang=eng
Patient-derived lung cancer organoids as in vitro cancer models for therapeutic ... antibody in herpes simplex virus-induced Behc et's disease mouse model ...
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41 Increased expression of selected very late antigen integrin ...
https://www.termedia.pl/Journal/-7/pdf-19653-10?filename=Increased%20expression.pdf
Anti-inflammatory effects of the VLA-1 antag- onists were observed in animal models of arthritis [11], ... This work was supported by KBN – the State Com-.
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42 A Pilot Study on Zinc Levels in Patients with Rheumatoid Arthritis
https://cyberleninka.org/article/n/214403.pdf
Rheumatoid arthritis (RA) is a well-studied progressive autoimmune ... has been previously studied in an experimental human model involving.
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43 Annals of the Rheumatic Diseases publishes
http://iranianra.ir/files/site1/Annals%20of%20the%20Rheumatic%20Diseases%202021%205.pdf
Rheumatoid arthritis analytes. Separate multivariable Cox proportional hazards models evaluated associations between each individual cytokine/.
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44 Investigations into σB-Modulated Regulatory Pathways ...
https://journals.asm.org/doi/10.1128/JB.00551-06
... been shown to be a pleiotropic regulator of virulence determinant production and to be required for pathogenesis in a septic arthritis model (23, 26).
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45 KBN Hospital, Erode, Tamil Nadu - 638001 - AreYouHealthy
https://areyouhealthy.in/hospital/tamil-nadu/erode/kbn-hospital-erode/
› hospital › kbn-hospital-erode
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46 Molecular Modeling Study of Leflunomide and Its Active ...
https://pubs.acs.org/doi/10.1021/ci049754d
5 In addition it is being employed in the treatment of rheumatoid arthritis. 6 It was quickly found 7 that Leflunomide decomposed in vivo to ...
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47 Blue Cbd Gummies – The Forest Academy • TFA
https://www.theforestacademy.org/jcdzcbd/blue-cbd-kbn-gummies
Where Can I Find Cbd Gummies For Arthritis? ... like Tian Suning and cbd gummies hong kong Ma Yun at the time, did not find a profitable model.
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48 King's Research Portal - King's College London
https://kclpure.kcl.ac.uk/portal/files/177148235/e054386.full.pdf
acute coronary syndrome49 and rheumatoid arthritis.78. The majority of these studies were conducted in Sweden informed by the GPCC model of care,24 45 49 78 ...
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49 Antibody-induced arthritis: disease mechanisms and genes involved ...
https://ur.booksc.eu/book/21982731/83e693
Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis | Kutty Selva Nandakumar, Rikard Holmdahl | download ...
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50 In vivo imaging of early stages of rheumatoid arthritis by α5β1 ...
https://ejnmmires.springeropen.com/articles/10.1186/s13550-019-0541-6
... value of PET imaging of integrin subtypes αvβ3 and α5β1 for early detection of RA foci in collagen-induced arthritis (CIA) mouse models.
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51 Antibody-Mediated Drug Delivery Systems: Concepts, ...
https://books.google.com/books?id=TrkvRc4hUP8C&pg=PA415&lpg=PA415&dq=kbn+arthritis+model&source=bl&ots=CJTNp4MCVn&sig=ACfU3U0g-dRl4u_14hFM7h8i9SNhIqnJjA&hl=en&sa=X&ved=2ahUKEwjql6CmzNT7AhXFi_0HHXUZDe0Q6AF6BQjVARAD
Another animal model used to study arthritis is that of the K/B×N mice ... of the polyclonal sera obtained from KBN mice, arthritis develops in naive mice: ...
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52 Research of Pathogenesis and Novel Therapeutics in Arthritis
https://books.google.com/books?id=PmGbDwAAQBAJ&pg=PA302&lpg=PA302&dq=kbn+arthritis+model&source=bl&ots=nSnzlaYQCJ&sig=ACfU3U0kXO7psxw9P0O9Bs9KEQ6GLdgMqA&hl=en&sa=X&ved=2ahUKEwjql6CmzNT7AhXFi_0HHXUZDe0Q6AF6BQjRARAD
Similar to CAIA, arthritis caused by KBN serum transfer is MHC independent. ... In this model, FcγRIII is required for inflammation and cartilage breakdown, ...
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53 Uveitis: Immunity, Genes and Microbes
https://books.google.com/books?id=ahxSEAAAQBAJ&pg=PA245&lpg=PA245&dq=kbn+arthritis+model&source=bl&ots=2_lhJhtxVz&sig=ACfU3U1UVimL1txRF6FHlgS5ztHyyii7Mg&hl=en&sa=X&ved=2ahUKEwjql6CmzNT7AhXFi_0HHXUZDe0Q6AF6BQjMARAD
... seen in autoreactive lymphocytes of KBN mice, which are a spontaneous autoimmune arthritis model and were tested at an early stage of the disease (40).
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