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1
The genetics of human ageing | Nature Reviews Genetics
https://www.nature.com/articles/s41576-019-0183-6
Genes that promote ageing include some that encode yolk proteins, consistent with a link between ageing and reproduction. Another pro-ageing protein is the ...
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https://www.nature.com/articles/s41576-019-0183-6
Genes that promote ageing include some that encode yolk proteins, consistent with a link between ageing and reproduction. Another pro-ageing protein is the ...
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2
Aging Genetics and Aging - PMC - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295054/
Aging is a multifactorial process that is determined by genetic and environmental factors. The genotype determines the variation in lifespan ...
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295054/
Aging is a multifactorial process that is determined by genetic and environmental factors. The genotype determines the variation in lifespan ...
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3
Genetics of aging - Wikipedia
https://en.wikipedia.org/wiki/Genetics_of_aging
Genetics of aging is generally concerned with life extension associated with genetic alterations, rather than with accelerated aging diseases leading to ...
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https://en.wikipedia.org/wiki/Genetics_of_aging
Genetics of aging is generally concerned with life extension associated with genetic alterations, rather than with accelerated aging diseases leading to ...
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4
Frontiers in Genetics | Genetics of Aging
https://www.frontiersin.org/journals/genetics/sections/genetics-of-aging
Part of the third most-cited genetics and heredity journal, this section publishes research probing the genetic and molecular bases of aging, ...
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https://www.frontiersin.org/journals/genetics/sections/genetics-of-aging
Part of the third most-cited genetics and heredity journal, this section publishes research probing the genetic and molecular bases of aging, ...
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5
Aging: Searching for the genetic key to a long and healthy life
https://elifesciences.org/articles/57242
A study of over 40,000 individuals suggests that carrying a small number of ultra-rare genetic variants is associated with a longer lifespan.
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https://elifesciences.org/articles/57242
A study of over 40,000 individuals suggests that carrying a small number of ultra-rare genetic variants is associated with a longer lifespan.
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6
The Genetics of Aging: A Vertebrate Perspective - Cell Press
https://www.cell.com/cell/pdf/S0092-8674(19)30221-1.pdf
This Review discusses advances in the genetic regulation of aging in vertebrates from work in mice, humans, and organisms with exceptional ...
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https://www.cell.com/cell/pdf/S0092-8674(19)30221-1.pdf
This Review discusses advances in the genetic regulation of aging in vertebrates from work in mice, humans, and organisms with exceptional ...
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7
Genetic influences on aging - ScienceDirect.com
https://www.sciencedirect.com/science/article/pii/S0531556596000794
I discuss several areas where genetics has been fruitfully applied to the study of the aging processes: human genes identified by “segmental progeroid” ...
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https://www.sciencedirect.com/science/article/pii/S0531556596000794
I discuss several areas where genetics has been fruitfully applied to the study of the aging processes: human genes identified by “segmental progeroid” ...
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8
Aging | Definition, Process, & Effects - Encyclopedia Britannica
https://www.britannica.com/science/aging-life-process
One theory of aging assumes that the life span of a cell or organism is genetically determined—that the genes of an animal contain a “program” that determines ...
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https://www.britannica.com/science/aging-life-process
One theory of aging assumes that the life span of a cell or organism is genetically determined—that the genes of an animal contain a “program” that determines ...
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9
Are Telomeres the Key to Aging and Cancer
https://learn.genetics.utah.edu/content/basics/telomeres/
Inside the nucleus of a cell, our genes are arranged along twisted, double-stranded molecules of DNA called chromosomes. At the ends of the chromosomes are ...
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https://learn.genetics.utah.edu/content/basics/telomeres/
Inside the nucleus of a cell, our genes are arranged along twisted, double-stranded molecules of DNA called chromosomes. At the ends of the chromosomes are ...
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10
The Genetic Basis of Aging: An Evolutionary Biologist's ...
https://www.science.org/doi/10.1126/sageke.2005.11.pe7
... the study of the genetic basis of aging from the viewpoint of an evolutionary biologist. Work in this area has revealed that homologous genes and pathw.
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https://www.science.org/doi/10.1126/sageke.2005.11.pe7
... the study of the genetic basis of aging from the viewpoint of an evolutionary biologist. Work in this area has revealed that homologous genes and pathw.
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11
Center for Genetic Disorders and Aging Research
https://www.sbpdiscovery.org/biomedical-research/centers/center-for-genetic-disorders-and-aging-research
Studying these proteins provides new clues to protecting our health. Learn More. Human Genetics Program. We are discovering the genetic roots of human disorders ...
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https://www.sbpdiscovery.org/biomedical-research/centers/center-for-genetic-disorders-and-aging-research
Studying these proteins provides new clues to protecting our health. Learn More. Human Genetics Program. We are discovering the genetic roots of human disorders ...
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12
GenAge: The Ageing Gene Database
https://genomics.senescence.info/genes/index.html
GenAge is divided into genes related to longevity and/or ageing in model organisms (yeast, worms, flies, mice, etc.) and ageing-related human genes. The section ...
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https://genomics.senescence.info/genes/index.html
GenAge is divided into genes related to longevity and/or ageing in model organisms (yeast, worms, flies, mice, etc.) and ageing-related human genes. The section ...
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13
Biological Age Measured Precisely by Gene Expression
https://www.genengnews.com/news/biological-age-measured-precisely-by-gene-expression/
New aging clock developed from organism's gene expression able to ... The new clock, however, takes into consideration the set of genes that ...
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https://www.genengnews.com/news/biological-age-measured-precisely-by-gene-expression/
New aging clock developed from organism's gene expression able to ... The new clock, however, takes into consideration the set of genes that ...
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14
Genetic associations for two biological age measures point to ...
https://onlinelibrary.wiley.com/doi/full/10.1111/acel.13376
Abstract Biological age measures outperform chronological age in predicting various aging outcomes, yet little is known regarding genetic ...
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https://onlinelibrary.wiley.com/doi/full/10.1111/acel.13376
Abstract Biological age measures outperform chronological age in predicting various aging outcomes, yet little is known regarding genetic ...
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15
Scientists identify genetic variants linked to mobility changes ...
https://www.sciencedaily.com/releases/2022/04/220426101758.htm
"While aging is universal, the genetic factors that contribute to differences among individuals as they age are unclear.
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https://www.sciencedaily.com/releases/2022/04/220426101758.htm
"While aging is universal, the genetic factors that contribute to differences among individuals as they age are unclear.
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16
Genetics & DNA: The Genetic Theory Of Aging
https://dcmp.org/media/7197-genetics-dna-the-genetic-theory-of-aging
Explains genetics, DNA, and genetic theories of aging. Illustrates the genetic processes behind cellular aging, and shows how genes affect life span.
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https://dcmp.org/media/7197-genetics-dna-the-genetic-theory-of-aging
Explains genetics, DNA, and genetic theories of aging. Illustrates the genetic processes behind cellular aging, and shows how genes affect life span.
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17
Genetic Variation and Human Aging: Progress and Prospects
https://academic.oup.com/biomedgerontology/article/62/3/301/655806
Finding the genetic variants that are common in the general population and contribute to aging processes in large numbers of people has proven very difficult.
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https://academic.oup.com/biomedgerontology/article/62/3/301/655806
Finding the genetic variants that are common in the general population and contribute to aging processes in large numbers of people has proven very difficult.
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18
Tanzi Lab - Genetics and Aging Research Unit
https://www.massgeneral.org/neurology/research/tanzi-lab-genetics-and-aging
Tanzi Lab - Genetics and Aging Research Unit. Dr. Rudolph Tanzi is identifying Alzheimer's disease genes and developing model systems to discover molecular ...
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https://www.massgeneral.org/neurology/research/tanzi-lab-genetics-and-aging
Tanzi Lab - Genetics and Aging Research Unit. Dr. Rudolph Tanzi is identifying Alzheimer's disease genes and developing model systems to discover molecular ...
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19
Natural genetic and phenotypic variation for aging
https://digital.lib.washington.edu/researchworks/handle/1773/46539
Evolutionary approaches to studying aging have largely utilized demography, population and quantitative genetics, and mathematical modeling methods to ...
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https://digital.lib.washington.edu/researchworks/handle/1773/46539
Evolutionary approaches to studying aging have largely utilized demography, population and quantitative genetics, and mathematical modeling methods to ...
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20
Decoding Longevity: 3 Genes Linked to Anti-Aging | Pfizer
https://www.pfizer.com/news/articles/decoding_longevity_3_genes_linked_to_anti_aging
The Sirtuin genes are a family of seven genes that encode for proteins that have been found across the evolution of many lifeforms. The expression of these ...
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https://www.pfizer.com/news/articles/decoding_longevity_3_genes_linked_to_anti_aging
The Sirtuin genes are a family of seven genes that encode for proteins that have been found across the evolution of many lifeforms. The expression of these ...
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21
Genetic Aspects of Vaginal Aging - Full Text View
https://www.clinicaltrials.gov/ct2/show/NCT05318989
The overwhelming majority are non-genetic determinants. ... Promoter methylation of specific genes involved in the aging process [ Time ...
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https://www.clinicaltrials.gov/ct2/show/NCT05318989
The overwhelming majority are non-genetic determinants. ... Promoter methylation of specific genes involved in the aging process [ Time ...
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22
Genetic basis of neurocognitive decline and reduced white ...
https://www.pnas.org/doi/10.1073/pnas.1313735110
SignificanceIdentification of genes associated with brain aging should improve our understanding of the biological processes that govern normal age-related ...
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https://www.pnas.org/doi/10.1073/pnas.1313735110
SignificanceIdentification of genes associated with brain aging should improve our understanding of the biological processes that govern normal age-related ...
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23
The genetic mechanisms of ageing | Karolinska Institutet
https://ki.se/en/research/the-genetic-mechanisms-of-ageing
Maria Eriksson has discovered the gene that causes premature ageing in children. She is now researching the general genetic causes of ageing and has shown, ...
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https://ki.se/en/research/the-genetic-mechanisms-of-ageing
Maria Eriksson has discovered the gene that causes premature ageing in children. She is now researching the general genetic causes of ageing and has shown, ...
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24
Genetic Variants Linked to Mobility Changes in Aging
https://gero.usc.edu/2022/05/02/genetic-variants-mobility-changes-in-aging/
“While aging is universal, the genetic factors that contribute to ... or ALDH4A1 gene can impact muscle aging in C. elegans and humans, ...
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https://gero.usc.edu/2022/05/02/genetic-variants-mobility-changes-in-aging/
“While aging is universal, the genetic factors that contribute to ... or ALDH4A1 gene can impact muscle aging in C. elegans and humans, ...
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25
Genetic basis of cardiovascular aging is at the core of human ...
https://cardiovascularaging.com/article/view/4763
Whereas the genetic basis of rare premature aging syndromes has been elucidated, only a small fraction of the genetic determinants of longevity and life span, ...
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https://cardiovascularaging.com/article/view/4763
Whereas the genetic basis of rare premature aging syndromes has been elucidated, only a small fraction of the genetic determinants of longevity and life span, ...
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26
Special Issue : Genetic and Environmental Factors in Ageing ...
https://www.mdpi.com/journal/genes/special_issues/Genetic_Ageing
This Special Issue of Genes aims to provide an overview of the latest research on genetic, epigenetic and environmental factors in human ageing, longevity and ...
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https://www.mdpi.com/journal/genes/special_issues/Genetic_Ageing
This Special Issue of Genes aims to provide an overview of the latest research on genetic, epigenetic and environmental factors in human ageing, longevity and ...
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27
Progeria - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/progeria/symptoms-causes/syc-20356038
Progeria is an extremely rare, progressive genetic disorder that causes ... a baby first shows the characteristic signs of premature aging.
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https://www.mayoclinic.org/diseases-conditions/progeria/symptoms-causes/syc-20356038
Progeria is an extremely rare, progressive genetic disorder that causes ... a baby first shows the characteristic signs of premature aging.
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28
These Are the Genes Behind Healthy Aging - TIME
https://time.com/4303334/genes-aging/
Topol says that it's likely that for healthy aging, it's necessary to both have genes that lower the risk of chronic diseases (such as avoiding ...
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https://time.com/4303334/genes-aging/
Topol says that it's likely that for healthy aging, it's necessary to both have genes that lower the risk of chronic diseases (such as avoiding ...
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29
DETECTABILITY OF SELECTED GENETIC MARKERS IN ...
https://www.ojp.gov/ncjrs/virtual-library/abstracts/detectability-selected-genetic-markers-dried-blood-upon-aging
EFFECTS OF VARYING PERIODS OF AGING, HIGH AND LOW HUMIDITY CONDITIONS, AND TYPES OF SUBSTRATE ON THE DETECTABILITY OF RED CELL ANTIGENS AND ENZYME SYSTEMS ...
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https://www.ojp.gov/ncjrs/virtual-library/abstracts/detectability-selected-genetic-markers-dried-blood-upon-aging
EFFECTS OF VARYING PERIODS OF AGING, HIGH AND LOW HUMIDITY CONDITIONS, AND TYPES OF SUBSTRATE ON THE DETECTABILITY OF RED CELL ANTIGENS AND ENZYME SYSTEMS ...
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30
Genetic Effects on Aging (Telford Press) II 1st Edition
https://www.amazon.com/Genetic-Effects-Aging-Telford-Press/dp/0936923318
Genetic Effects on Aging (Telford Press) II: 9780936923314: Medicine & Health Science Books @ Amazon.com.
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https://www.amazon.com/Genetic-Effects-Aging-Telford-Press/dp/0936923318
Genetic Effects on Aging (Telford Press) II: 9780936923314: Medicine & Health Science Books @ Amazon.com.
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31
Genetic Data - the Health and Retirement Study
https://hrs.isr.umich.edu/data-products/genetic-data
Data are distributed through the NCBI Database of Genotypes and Phenotypes (dbGaP), the National Institute on Aging Genetics of Alzheimer's Disease Data ...
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https://hrs.isr.umich.edu/data-products/genetic-data
Data are distributed through the NCBI Database of Genotypes and Phenotypes (dbGaP), the National Institute on Aging Genetics of Alzheimer's Disease Data ...
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32
Genetic Factors - UCSF Memory and Aging Center
https://memory.ucsf.edu/genetic-factors
Genetic Factors. Genetics is the study of heredity in living organisms. ... Autosomal dominant: This pattern of inheritance is caused by a genetic mutation ...
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https://memory.ucsf.edu/genetic-factors
Genetic Factors. Genetics is the study of heredity in living organisms. ... Autosomal dominant: This pattern of inheritance is caused by a genetic mutation ...
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33
“Genetic Baggage” Accumulates in the Genomes of Aging ...
https://www.bumc.bu.edu/busm/2022/03/04/genetic-baggage-accumulates-in-the-genomes-of-aging-mutant-animals/
Frontiers in Genetics of Aging 2012;2. Middle Age Mothers Live Longer. There is a growing body of evidence for a substantial genetic influence upon survival to ...
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https://www.bumc.bu.edu/busm/2022/03/04/genetic-baggage-accumulates-in-the-genomes-of-aging-mutant-animals/
Frontiers in Genetics of Aging 2012;2. Middle Age Mothers Live Longer. There is a growing body of evidence for a substantial genetic influence upon survival to ...
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34
Effect of longevity genetic variants on the molecular aging rate
https://link.springer.com/article/10.1007/s11357-021-00376-4
The analysis also discovered and replicated associations between longevity variants and slower changes of protein biomarkers of aging, including ...
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https://link.springer.com/article/10.1007/s11357-021-00376-4
The analysis also discovered and replicated associations between longevity variants and slower changes of protein biomarkers of aging, including ...
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35
Genetics of Longevity and Aging | Annual Review of Medicine
https://www.annualreviews.org/doi/10.1146/annurev.med.56.082103.104617
Longevity has a strong genetic component, as has become apparent from ... In humans, private aging genes could explain certain age-related ...
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https://www.annualreviews.org/doi/10.1146/annurev.med.56.082103.104617
Longevity has a strong genetic component, as has become apparent from ... In humans, private aging genes could explain certain age-related ...
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36
Discovery Talk: A Genetic Control Circuit for Aging - iBiology
https://www.ibiology.org/genetics-and-gene-regulation/circuit-for-aging/
In her talk about discovering a genetic control circuit for aging, Cynthia Kenyon describes how a single gene mutation causes C. elegans to live twice as ...
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https://www.ibiology.org/genetics-and-gene-regulation/circuit-for-aging/
In her talk about discovering a genetic control circuit for aging, Cynthia Kenyon describes how a single gene mutation causes C. elegans to live twice as ...
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37
JAX Center for Aging Research - The Jackson Laboratory
https://www.jax.org/research-and-faculty/research-centers/aging-center
We are developing and disseminating the next generation of genetic, statistical and information resources necessary to foster research into age-related diseases ...
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https://www.jax.org/research-and-faculty/research-centers/aging-center
We are developing and disseminating the next generation of genetic, statistical and information resources necessary to foster research into age-related diseases ...
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38
Genetic variants specific to aging-related verbal memory - PLOS
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182448
(2017) Genetic variants specific to aging-related verbal memory: Insights from GWASs in a population-based cohort. PLoS ONE 12(8): e0182448.
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182448
(2017) Genetic variants specific to aging-related verbal memory: Insights from GWASs in a population-based cohort. PLoS ONE 12(8): e0182448.
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39
Scientist's research seeks to identify critical genetic triggers ...
https://news.stanford.edu/news/2006/november8/med-aging-110806.html
The notion of aging as a haphazard process is fast losing ground at the frontiers of genetic research where today scientists such as Anne ...
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https://news.stanford.edu/news/2006/november8/med-aging-110806.html
The notion of aging as a haphazard process is fast losing ground at the frontiers of genetic research where today scientists such as Anne ...
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40
Genetic study provides evidence that alcohol accelerates ...
https://www.ox.ac.uk/news/2022-07-26-genetic-study-provides-evidence-alcohol-accelerates-biological-aging
Telomere length is considered an indicator of biological aging, since 50-100 DNA bases are lost each time a cell replicates. Once telomeres ...
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https://www.ox.ac.uk/news/2022-07-26-genetic-study-provides-evidence-alcohol-accelerates-biological-aging
Telomere length is considered an indicator of biological aging, since 50-100 DNA bases are lost each time a cell replicates. Once telomeres ...
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41
Dog Aging Project, a resource for scientists in many fields
https://newsroom.uw.edu/news/dog-aging-project-resource-scientists-many-fields
Max mix breed dog genetics dog aging. Barbara Clements. The owners of Max, a mix breed adopted from a shelter, recently learned his genetic ...
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https://newsroom.uw.edu/news/dog-aging-project-resource-scientists-many-fields
Max mix breed dog genetics dog aging. Barbara Clements. The owners of Max, a mix breed adopted from a shelter, recently learned his genetic ...
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42
Genetic changes associated with dog aging are more about ...
https://phys.org/news/2022-03-genetic-dog-aging-quantity-quality.html
Investigating the activity of genes in dog brain tissues revealed that a ... This indicates that genetic changes associated with aging are ...
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https://phys.org/news/2022-03-genetic-dog-aging-quantity-quality.html
Investigating the activity of genes in dog brain tissues revealed that a ... This indicates that genetic changes associated with aging are ...
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43
Study Identifies Genetic Variants That May Contribute to ...
https://ascopost.com/news/march-2022/study-identifies-genetic-variants-that-may-contribute-to-accelerated-aging-in-childhood-cancer-survivors/
Jude Children's Research Hospital have identified variants in two genes that may be associated with accelerated aging in childhood cancer ...
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https://ascopost.com/news/march-2022/study-identifies-genetic-variants-that-may-contribute-to-accelerated-aging-in-childhood-cancer-survivors/
Jude Children's Research Hospital have identified variants in two genes that may be associated with accelerated aging in childhood cancer ...
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44
Human longevity: 25 genetic loci associated in ... - Aging-US
https://www.aging-us.com/article/101334/text
› article › text
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https://www.aging-us.com/article/101334/text
› article › text
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45
Genetic and genomic factors in aging
https://www.cambridge.org/core/journals/reviews-in-clinical-gerontology/article/genetic-and-genomic-factors-in-aging/7F7C8765525B5B6D8C5661CEFDEE88A6
9Hayflick, L. Prospects of human life extension by genetic manipulation. In: Danon, D, Shock, NW, Marois, M eds. Aging: a challenge to science and society, ...
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https://www.cambridge.org/core/journals/reviews-in-clinical-gerontology/article/genetic-and-genomic-factors-in-aging/7F7C8765525B5B6D8C5661CEFDEE88A6
9Hayflick, L. Prospects of human life extension by genetic manipulation. In: Danon, D, Shock, NW, Marois, M eds. Aging: a challenge to science and society, ...
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46
Why Do We Age, and Can Anything Be Done to Stop or Slow it?
https://www.healthline.com/health/why-do-we-age
Some aging theories suggest cells have a predetermined lifespan, while others claim it's caused by damage, genetics, evolution, ...
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https://www.healthline.com/health/why-do-we-age
Some aging theories suggest cells have a predetermined lifespan, while others claim it's caused by damage, genetics, evolution, ...
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47
Genetic variants predictive of reproductive aging are associ...
https://journals.lww.com/menopausejournal/Fulltext/2021/08000/Genetic_variants_predictive_of_reproductive_aging.8.aspx
Genetic variants predictive of reproductive aging are associated with vasomotor symptoms in a multiracial/ethnic cohort. Zhao, Wei PhD 1; Smith, ...
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https://journals.lww.com/menopausejournal/Fulltext/2021/08000/Genetic_variants_predictive_of_reproductive_aging.8.aspx
Genetic variants predictive of reproductive aging are associated with vasomotor symptoms in a multiracial/ethnic cohort. Zhao, Wei PhD 1; Smith, ...
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48
NIAGADS |
https://www.niagads.org/
Explore genetics and genomics of Alzheimer's disease. Access AD genomics resources through NIAGADS and other partner sites. The National Institute on Aging ...
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https://www.niagads.org/
Explore genetics and genomics of Alzheimer's disease. Access AD genomics resources through NIAGADS and other partner sites. The National Institute on Aging ...
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49
Ageing genetic signature of hypersomatotropism | Open Biology
https://royalsocietypublishing.org/doi/10.1098/rsob.200265
Enrichment database analysis and gene ontology showed that most overlapping muscle genes were involved in ageing metabolism, while overlapping ...
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https://royalsocietypublishing.org/doi/10.1098/rsob.200265
Enrichment database analysis and gene ontology showed that most overlapping muscle genes were involved in ageing metabolism, while overlapping ...
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50
Scientists can reverse aging in mice. The goal is to do ... - CNN
https://www.cnn.com/2022/06/02/health/reverse-aging-life-itself-scn-wellness/index.html
While we wait for science to determine if we too can reset our genes, there are many other ways to slow the aging process and reset our ...
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https://www.cnn.com/2022/06/02/health/reverse-aging-life-itself-scn-wellness/index.html
While we wait for science to determine if we too can reset our genes, there are many other ways to slow the aging process and reset our ...
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51
Study offers genetic insights into the underlying biology of ...
https://www.news-medical.net/news/20210804/Study-offers-genetic-insights-into-the-underlying-biology-of-reproductive-aging.aspx
The age at which women go through menopause is critical for fertility and impacts healthy ageing in women, but reproductive ageing has been ...
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https://www.news-medical.net/news/20210804/Study-offers-genetic-insights-into-the-underlying-biology-of-reproductive-aging.aspx
The age at which women go through menopause is critical for fertility and impacts healthy ageing in women, but reproductive ageing has been ...
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52
A new genetic pathway that prevents early aging - CT Plus
https://www.utsouthwestern.edu/ctplus/stories/2019/aging-genetic-pathway.html
Building upon their earlier discoveries, researchers at UT Southwestern have identified a new genetic pathway that prevents premature aging.
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https://www.utsouthwestern.edu/ctplus/stories/2019/aging-genetic-pathway.html
Building upon their earlier discoveries, researchers at UT Southwestern have identified a new genetic pathway that prevents premature aging.
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53
Gene regulation may hold clue to longer life : News Center
https://www.rochester.edu/newscenter/the-secret-to-a-longer-lifespan-gene-regulation-holds-a-clue-523672/
Rochester biologists who study the genetics of lifespan suggest gene regulation may be a new target to combat aging and age-related ...
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https://www.rochester.edu/newscenter/the-secret-to-a-longer-lifespan-gene-regulation-holds-a-clue-523672/
Rochester biologists who study the genetics of lifespan suggest gene regulation may be a new target to combat aging and age-related ...
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54
Can We Stop the Heart From Aging? This Landmark Genetic ...
https://singularityhub.com/2022/08/23/can-we-stop-the-heart-from-aging-scientists-sequenced-single-heart-cells-as-a-start/
The team sequenced the entire genome of 56 heart muscle cells, yielding the first landscape painting of genetic changes in an aging heart.
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https://singularityhub.com/2022/08/23/can-we-stop-the-heart-from-aging-scientists-sequenced-single-heart-cells-as-a-start/
The team sequenced the entire genome of 56 heart muscle cells, yielding the first landscape painting of genetic changes in an aging heart.
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55
Biological aging - Genetic curiosities - ADNTRO
https://adntro.com/en/blog/genetic-curiosities/biological-aging/
Biological aging is determined by telomeres. Telomere length varies based on age, genetics (influence of 20%) and our lifestyle habits.
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https://adntro.com/en/blog/genetic-curiosities/biological-aging/
Biological aging is determined by telomeres. Telomere length varies based on age, genetics (influence of 20%) and our lifestyle habits.
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56
Genetic Skin Diseases With Altered Aging | JAMA Dermatology
https://jamanetwork.com/journals/jamadermatology/fullarticle/559369
Genetic Skin Diseases With Altered Aging ... A challenge for current investigators is to understand how a genetic defect, identified by a DNA mutation, ...
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https://jamanetwork.com/journals/jamadermatology/fullarticle/559369
Genetic Skin Diseases With Altered Aging ... A challenge for current investigators is to understand how a genetic defect, identified by a DNA mutation, ...
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57
Genetic Analyses of Epigenetic Predictors that Estimate Aging ...
https://www.biorxiv.org/content/10.1101/2021.06.23.449634v1
DNA methylation (DNAm) clocks are accurate molecular biomarkers of aging. However, the clock mechanisms remain unclear.
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https://www.biorxiv.org/content/10.1101/2021.06.23.449634v1
DNA methylation (DNAm) clocks are accurate molecular biomarkers of aging. However, the clock mechanisms remain unclear.
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58
Aging and chronic diseases share genetic factors, study reveals
https://www.eurekalert.org/news-releases/856453
Three of the genes affecting healthspan, HLA-DBQ, LPA, and CDKN2B, were previously associated with parental longevity, a proxy for overall life ...
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https://www.eurekalert.org/news-releases/856453
Three of the genes affecting healthspan, HLA-DBQ, LPA, and CDKN2B, were previously associated with parental longevity, a proxy for overall life ...
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59
Ageing: The girls who never grow older - BBC Future
https://www.bbc.com/future/article/20140520-the-girls-who-never-age
She had a genetic disease that stopped her development and with it, Walker suspected, the ageing process. Brooke Greenberg, in other words, ...
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https://www.bbc.com/future/article/20140520-the-girls-who-never-age
She had a genetic disease that stopped her development and with it, Walker suspected, the ageing process. Brooke Greenberg, in other words, ...
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60
Scientists reverse genetic aging, memory decline in rats
https://www.medicalnewstoday.com/articles/320412
A calcium-regulating protein gives insight into memory decline in aging. Increasing levels of this protein reversed age-related genetic ...
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https://www.medicalnewstoday.com/articles/320412
A calcium-regulating protein gives insight into memory decline in aging. Increasing levels of this protein reversed age-related genetic ...
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61
Genetic and Phenotypic Evidence for the Causal Relationship ...
https://www.medrxiv.org/content/10.1101/2020.08.06.20169854.full
Epidemiological studies revealed that the elderly and those with co-morbidities are most susceptible to COVID-19. To understand how genetics ...
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https://www.medrxiv.org/content/10.1101/2020.08.06.20169854.full
Epidemiological studies revealed that the elderly and those with co-morbidities are most susceptible to COVID-19. To understand how genetics ...
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62
The Dog Aging Project: Genetic and Environmental ...
https://grantome.com/grant/NIH/U19-AG057377-01
OVERALL ? THE DOG AGING PROJECT: GENETIC AND ENVIRONMENTAL DETERMINANTS OF HEALTHY AGING IN COMPANION DOGS ABSTRACT Age is the single greatest risk factor ...
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https://grantome.com/grant/NIH/U19-AG057377-01
OVERALL ? THE DOG AGING PROJECT: GENETIC AND ENVIRONMENTAL DETERMINANTS OF HEALTHY AGING IN COMPANION DOGS ABSTRACT Age is the single greatest risk factor ...
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63
Genes vs. Lifestyle: Which Matters More for Health? - WebMD
https://www.webmd.com/healthy-aging/features/genes-or-lifestyle
They play such a big role in so-called “diseases of aging” – like diabetes and heart disease, Kelly says, that they are better described as ...
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https://www.webmd.com/healthy-aging/features/genes-or-lifestyle
They play such a big role in so-called “diseases of aging” – like diabetes and heart disease, Kelly says, that they are better described as ...
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64
Research identifies key genetic link in the biology of aging
https://lpi.oregonstate.edu/feature-story/research-identifies-key-genetic-link-biology-aging
Research identifies key genetic link in the biology of aging ... CORVALLIS, Ore. – New research at the Linus Pauling Institute at Oregon State University suggests ...
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https://lpi.oregonstate.edu/feature-story/research-identifies-key-genetic-link-biology-aging
Research identifies key genetic link in the biology of aging ... CORVALLIS, Ore. – New research at the Linus Pauling Institute at Oregon State University suggests ...
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65
Study details genetic basis of aging — and how it might be ...
https://news.wisc.edu/study-details-genetic-basis-of-aging-and-how-it-might-be-delayed/
The study is a milestone in aging research, providing scientists with an intimate look at the ebb and flow of genetic activity with age, and the ...
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https://news.wisc.edu/study-details-genetic-basis-of-aging-and-how-it-might-be-delayed/
The study is a milestone in aging research, providing scientists with an intimate look at the ebb and flow of genetic activity with age, and the ...
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66
LONGEVITY, GENES, AND AGING: A VIEW PROVIDED BY A ...
http://www.medschool.lsuhsc.edu/biochemistry/PDF%20files/Jazwinski/EGreview.pdf
Abstract—The genetic analysis of aging in the yeast Saccharomyces cerevisiae has revealed the importance of metabolic capacity, resistance to stress, ...
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http://www.medschool.lsuhsc.edu/biochemistry/PDF%20files/Jazwinski/EGreview.pdf
Abstract—The genetic analysis of aging in the yeast Saccharomyces cerevisiae has revealed the importance of metabolic capacity, resistance to stress, ...
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67
Ageing and health - World Health Organization (WHO)
https://www.who.int/news-room/fact-sheets/detail/ageing-and-health
Although some of the variations in older people's health are genetic, most is due to people's physical and social environments – including their ...
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https://www.who.int/news-room/fact-sheets/detail/ageing-and-health
Although some of the variations in older people's health are genetic, most is due to people's physical and social environments – including their ...
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68
Genetic instability and aging: theories, facts, and future ...
https://cdnsciencepub.com/doi/10.1139/g89-057
Key words: genetic instability, DNA and aging, gene expression, somatic mutations, DNA methylation, evolutionary aspects.
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https://cdnsciencepub.com/doi/10.1139/g89-057
Key words: genetic instability, DNA and aging, gene expression, somatic mutations, DNA methylation, evolutionary aspects.
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69
Genetic Factors Associated with Increased Longevity Identified
https://www.scientificamerican.com/article/genetic-factors-associated-with-increased-longevity-identified/
Studies show that Seventh-Day Adventists, whose church encourages behaviors that promote healthy aging, have a well-documented average life ...
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https://www.scientificamerican.com/article/genetic-factors-associated-with-increased-longevity-identified/
Studies show that Seventh-Day Adventists, whose church encourages behaviors that promote healthy aging, have a well-documented average life ...
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70
Genetic Study Improves Lifespan Predictions and Scientific ...
https://www.ashg.org/publications-news/press-releases/201810-lifespan/
Realizing the benefits of human genetics and genomics research for people ... Lifespan Predictions and Scientific Understanding of Aging.
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https://www.ashg.org/publications-news/press-releases/201810-lifespan/
Realizing the benefits of human genetics and genomics research for people ... Lifespan Predictions and Scientific Understanding of Aging.
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71
Skin aging: Genetic nuances - Dermatology Times
https://www.dermatologytimes.com/view/skin-aging-genetic-nuances
“Certain changes take place in the skin naturally due to the passage of time, but genetics also play a role in intrinsic aging,” says Dr.
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https://www.dermatologytimes.com/view/skin-aging-genetic-nuances
“Certain changes take place in the skin naturally due to the passage of time, but genetics also play a role in intrinsic aging,” says Dr.
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72
Uncovering genetic mechanisms of kidney aging through ...
https://www.kidney-international.org/article/S0085-2538(18)30837-8/fulltext
Nephrons scar and involute during aging, increasing the risk of chronic kidney disease. Little is known, however, about genetic mechanisms ...
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https://www.kidney-international.org/article/S0085-2538(18)30837-8/fulltext
Nephrons scar and involute during aging, increasing the risk of chronic kidney disease. Little is known, however, about genetic mechanisms ...
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73
Genetic Effects on Cognition are Stronger as We Age
https://www.cogneurosociety.org/genetic-effects_cognition_aging_papenberg_aug15/
In older age, brain resources are lowered due to aging-related declines in brain integrity. In young age, brain resources are high and ...
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https://www.cogneurosociety.org/genetic-effects_cognition_aging_papenberg_aug15/
In older age, brain resources are lowered due to aging-related declines in brain integrity. In young age, brain resources are high and ...
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74
Longevity Genes Project | Institute for Aging Research
https://www.einsteinmed.edu/centers/aging/longevity-genes-project/
Nir Barzilai and his team conducted genetic research on more than 500 healthy elderly people between the ages of 95 and 112 and on their children. The ...
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https://www.einsteinmed.edu/centers/aging/longevity-genes-project/
Nir Barzilai and his team conducted genetic research on more than 500 healthy elderly people between the ages of 95 and 112 and on their children. The ...
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75
Racism may accelerate aging on a genetic level, study finds
https://www.pbs.org/newshour/science/racism-makes-you-age-faster-on-a-genetic-level-study-finds
Can experiencing discrimination lead to premature aging? Researchers think there could be a connection. According the Centers for Disease ...
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https://www.pbs.org/newshour/science/racism-makes-you-age-faster-on-a-genetic-level-study-finds
Can experiencing discrimination lead to premature aging? Researchers think there could be a connection. According the Centers for Disease ...
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76
Older Adults' Views on Genetic Testing
https://www.healthyagingpoll.org/reports-more/report/older-adults-views-genetic-testing
In March 2018, the University of Michigan National Poll on Healthy Aging asked a national sample of adults age 50–64 about their experiences and ...
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https://www.healthyagingpoll.org/reports-more/report/older-adults-views-genetic-testing
In March 2018, the University of Michigan National Poll on Healthy Aging asked a national sample of adults age 50–64 about their experiences and ...
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77
NIH taps Tulane neuroscientist to lead effort to standardize ...
https://news.tulane.edu/pr/nih-taps-tulane-neuroscientist-lead-effort-standardize-research-genetic-aging
... to lead effort to standardize research in genetic aging ... length and how it can be used as a sentinel of aging-related disease risk.
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https://news.tulane.edu/pr/nih-taps-tulane-neuroscientist-lead-effort-standardize-research-genetic-aging
... to lead effort to standardize research in genetic aging ... length and how it can be used as a sentinel of aging-related disease risk.
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78
Genetic and Chemical Effects on Somatic and Germline Aging
https://www.hindawi.com/journals/omcl/2020/4684890/
Somatic aging is a complex process characterized by gradual deterioration of physiological function that is observed at the genetic, ...
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https://www.hindawi.com/journals/omcl/2020/4684890/
Somatic aging is a complex process characterized by gradual deterioration of physiological function that is observed at the genetic, ...
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79
The Aging Factor You Can't Really Control: Genes
https://www.northwestpharmacy.com/healthperch/the-aging-factor-you-cant-really-control-genes
This DNA contains genes only from mothers. As it becomes damaged over time, the cell's energy production slows down, which results in aging.
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https://www.northwestpharmacy.com/healthperch/the-aging-factor-you-cant-really-control-genes
This DNA contains genes only from mothers. As it becomes damaged over time, the cell's energy production slows down, which results in aging.
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80
Scientists Link Rare Genetic Phenomenon to Neuron Function ...
https://news.unchealthcare.org/2022/11/scientists-link-rare-genetic-phenomenon-to-neuron-function-schizophrenia/
Home / Genetics And Aging / Scientists Link Rare Genetic Phenomenon to ... found that a rare form of a common genetic variant called tandem ...
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https://news.unchealthcare.org/2022/11/scientists-link-rare-genetic-phenomenon-to-neuron-function-schizophrenia/
Home / Genetics And Aging / Scientists Link Rare Genetic Phenomenon to ... found that a rare form of a common genetic variant called tandem ...
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81
Scientists discover key driver of human aging - Salk Institute
https://www.salk.edu/news-release/scientists-discover-key-driver-of-human-aging/
Salk Institute findings on premature aging syndrome could lead to way of ... Werner syndrome is a genetic disorder that causes people to age ...
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https://www.salk.edu/news-release/scientists-discover-key-driver-of-human-aging/
Salk Institute findings on premature aging syndrome could lead to way of ... Werner syndrome is a genetic disorder that causes people to age ...
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82
Natural variants in genetic system that affects aging ... - UAB
https://www.uab.edu/news/research/item/6109-natural-variants-in-genetic-system-that-affects-aging-found-in-new-uab-study
A study of the rapid evolution of the insulin-signaling molecular network that regulates growth, reproduction, metabolism and aging lays ...
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https://www.uab.edu/news/research/item/6109-natural-variants-in-genetic-system-that-affects-aging-found-in-new-uab-study
A study of the rapid evolution of the insulin-signaling molecular network that regulates growth, reproduction, metabolism and aging lays ...
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83
Scientists Have Found the First Ever Anti-Aging Genetic ...
https://futurism.com/neoscope/scientists-found-first-anti-aging-genetic-mutation
The genes of an Indiana Amish community may host a secret humans have pursued for much of living memory: the anti-aging key to longer and healthier lives.
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https://futurism.com/neoscope/scientists-found-first-anti-aging-genetic-mutation
The genes of an Indiana Amish community may host a secret humans have pursued for much of living memory: the anti-aging key to longer and healthier lives.
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84
Finding Genetic Signatures of Aging | by Gunnar De Winter
https://medium.com/predict/finding-genetic-signatures-of-aging-3a85afdcebe5
A new study uses a mouse cell atlas to identify both general and tissue-specific genetic aging signatures. (Pixabay, geralt) ...
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https://medium.com/predict/finding-genetic-signatures-of-aging-3a85afdcebe5
A new study uses a mouse cell atlas to identify both general and tissue-specific genetic aging signatures. (Pixabay, geralt) ...
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85
Addressing Accelerated Genetic Aging in African Americans
https://today.uconn.edu/2018/11/addressing-accelerated-genetic-aging-african-americans/
Accelerated epigenetic aging can result from a number of factors including genetics, stress, and lifestyle habits. African Americans are ...
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https://today.uconn.edu/2018/11/addressing-accelerated-genetic-aging-african-americans/
Accelerated epigenetic aging can result from a number of factors including genetics, stress, and lifestyle habits. African Americans are ...
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86
Mom's Genes May Affect How Fast You Age - Live Science
https://www.livescience.com/39062-mother-genes-aging.html
... help keep people young at heart, but mutated genes passed down from mothers may also predetermine aging rates, new research suggests.
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https://www.livescience.com/39062-mother-genes-aging.html
... help keep people young at heart, but mutated genes passed down from mothers may also predetermine aging rates, new research suggests.
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87
Time-dependent genetic effects on gene expression implicate ...
https://genome.cshlp.org/content/27/4/545.short
In addition, we identified 2213 genes differentially expressed across time points that we linked with aging within and across studies.
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https://genome.cshlp.org/content/27/4/545.short
In addition, we identified 2213 genes differentially expressed across time points that we linked with aging within and across studies.
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88
New thinking on the process of ageing
https://cancergrandchallenges.org/news/new-thinking-process-ageing
A popular current model of ageing – the somatic mutation theory ... The study, published in Nature Genetics, reveals how human cells and ...
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https://cancergrandchallenges.org/news/new-thinking-process-ageing
A popular current model of ageing – the somatic mutation theory ... The study, published in Nature Genetics, reveals how human cells and ...
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89
Aging, Genetics and DNA Repair | Psychology Today
https://www.psychologytoday.com/us/blog/the-art-and-science-aging-well/201701/aging-genetics-and-dna-repair
There is little doubt that genetic mechanisms have an impact on aging. Different species have widely divergent lifespans. Even different breeds ...
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https://www.psychologytoday.com/us/blog/the-art-and-science-aging-well/201701/aging-genetics-and-dna-repair
There is little doubt that genetic mechanisms have an impact on aging. Different species have widely divergent lifespans. Even different breeds ...
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90
Healthy Aging May Not Require Winning The Genetic Lottery
https://www.kpbs.org/news/health/2016/04/21/san-diego-study-healthy-aging-may-not-require-winn
San Diego scientists found that people who live into their 80s and above with their health intact may have some genetic protections, ...
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https://www.kpbs.org/news/health/2016/04/21/san-diego-study-healthy-aging-may-not-require-winn
San Diego scientists found that people who live into their 80s and above with their health intact may have some genetic protections, ...
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91
Newly Discovered Cluster of Genes Increases Longevity
https://scitechdaily.com/newly-discovered-cluster-of-genes-increases-longevity/
DNA Genetics Breakthrough Concept ... on Aging (NIA), has reported the finding of numerous candidate genes that influence longevity.
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https://scitechdaily.com/newly-discovered-cluster-of-genes-increases-longevity/
DNA Genetics Breakthrough Concept ... on Aging (NIA), has reported the finding of numerous candidate genes that influence longevity.
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92
A Genetic Fountain of Youth?
https://www.genome.gov/27549916/a-genetic-fountain-of-youth
Some turn to surgical remedies to combat these less-than-glamorous side effects of aging. Beyond surgical reversal, scientists have worked ...
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https://www.genome.gov/27549916/a-genetic-fountain-of-youth
Some turn to surgical remedies to combat these less-than-glamorous side effects of aging. Beyond surgical reversal, scientists have worked ...
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93
Genetic polymorphisms and skin aging - Dove Medical Press
https://www.dovepress.com/genetic-polymorphisms-and-skin-aging-the-identification-of-population--peer-reviewed-fulltext-article-CCID
Genetic polymorphisms and skin aging: the identification of population genotypic groups holds potential for personalized treatments Jordi ...
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https://www.dovepress.com/genetic-polymorphisms-and-skin-aging-the-identification-of-population--peer-reviewed-fulltext-article-CCID
Genetic polymorphisms and skin aging: the identification of population genotypic groups holds potential for personalized treatments Jordi ...
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