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Google Keyword Rankings for : alternative splicing bcl x
1
Modulation of the Apoptosis Gene Bcl-x Function ... - Frontiers
https://www.frontiersin.org/articles/10.3389/fgene.2019.00804/full
An alternative splicing (AS) event in exon 2 of Bcl-x results in two isoforms of Bcl-x with antagonistic effects on cell survival: Bcl-xL ...
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https://www.frontiersin.org/articles/10.3389/fgene.2019.00804/full
An alternative splicing (AS) event in exon 2 of Bcl-x results in two isoforms of Bcl-x with antagonistic effects on cell survival: Bcl-xL ...
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2
Alternative splicing of BCL-X and implications for treating ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323006/
It is well-known that >90% of human genes undergo alternative splicing. A total of 10 distinct splicing transcripts of the BCL-X gene have been identified, ...
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323006/
It is well-known that >90% of human genes undergo alternative splicing. A total of 10 distinct splicing transcripts of the BCL-X gene have been identified, ...
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3
Regulation of alternative splicing of Bcl-x by IL-6, GM-CSF and ...
https://www.nature.com/articles/7290250
A number of genes involved in cell proliferation and apoptosis undergo alternative splicing, producing variants with different or even ...
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https://www.nature.com/articles/7290250
A number of genes involved in cell proliferation and apoptosis undergo alternative splicing, producing variants with different or even ...
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4
Anticancer drugs affect the alternative splicing of Bcl-x and ...
https://aacrjournals.org/mct/article/7/6/1398/235733/Anticancer-drugs-affect-the-alternative-splicing
We find that many anticancer drugs can shift Bcl-x pre-mRNA splicing to the proapoptotic Bcl-xS splice variant in different cell lines.
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https://aacrjournals.org/mct/article/7/6/1398/235733/Anticancer-drugs-affect-the-alternative-splicing
We find that many anticancer drugs can shift Bcl-x pre-mRNA splicing to the proapoptotic Bcl-xS splice variant in different cell lines.
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5
Modification of Alternative Splicing of Bcl-x Pre-mRNA in ...
https://www.jbc.org/article/S0021-9258(19)32071-X/pdf
Modification of Alternative Splicing of Bcl-x Pre-mRNA in Prostate and Breast Cancer Cells. ANALYSIS OF APOPTOSIS AND CELL DEATH*.
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https://www.jbc.org/article/S0021-9258(19)32071-X/pdf
Modification of Alternative Splicing of Bcl-x Pre-mRNA in Prostate and Breast Cancer Cells. ANALYSIS OF APOPTOSIS AND CELL DEATH*.
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6
Protein Kinase C-Dependent Control of Bcl-x Alternative ...
https://journals.asm.org/doi/10.1128/MCB.00565-07
In contrast to the case for 293 cells, PKC inhibitors do not influence the alternative splicing of Bcl-x and Axl in cancer cell lines, ...
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https://journals.asm.org/doi/10.1128/MCB.00565-07
In contrast to the case for 293 cells, PKC inhibitors do not influence the alternative splicing of Bcl-x and Axl in cancer cell lines, ...
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7
Specific G-quadruplex ligands modulate the alternative ...
https://academic.oup.com/nar/article/46/2/886/4634008
We have shown previously that two G4s form in Bcl-X pre-mRNA, one close to each of the two alternative 5′SS. If these G4s affect splicing ...
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https://academic.oup.com/nar/article/46/2/886/4634008
We have shown previously that two G4s form in Bcl-X pre-mRNA, one close to each of the two alternative 5′SS. If these G4s affect splicing ...
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8
The transcription factor FBI‐1 inhibits SAM68‐mediated BCL ...
https://www.embopress.org/doi/10.1002/embr.201338241
The oncogenic transcription factor FBI-1 regulates alternative splicing by preventing the splicing regulator SAM68 from binding to BCL-X mRNA.
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https://www.embopress.org/doi/10.1002/embr.201338241
The oncogenic transcription factor FBI-1 regulates alternative splicing by preventing the splicing regulator SAM68 from binding to BCL-X mRNA.
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9
Bcl-x Pre-mRNA Splicing Regulates Brain Injury after ...
https://www.jneurosci.org/content/jneuro/32/39/13587.full.pdf
isoforms of Bcl-x are produced as a result of alternative pre-mRNA splicing: Bcl-xL (the long form) is anti-apoptotic, while Bcl-xS (short.
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https://www.jneurosci.org/content/jneuro/32/39/13587.full.pdf
isoforms of Bcl-x are produced as a result of alternative pre-mRNA splicing: Bcl-xL (the long form) is anti-apoptotic, while Bcl-xS (short.
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10
Relative strength of 5' splice-site strength defines functions of ...
https://www.bmbreports.org/journal/view.html?uid=1567
Alternative splicing of Bcl-x pre-mRNA through alternative 5' splice-site selection produces an anti-apoptotic mRNA isoform that includes exon 2b and a ...
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https://www.bmbreports.org/journal/view.html?uid=1567
Alternative splicing of Bcl-x pre-mRNA through alternative 5' splice-site selection produces an anti-apoptotic mRNA isoform that includes exon 2b and a ...
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11
Differential Impacts of Alternative Splicing Networks on ... - MDPI
https://www.mdpi.com/1422-0067/17/12/2097
The Bcl-x gene was characterized as generating alternative transcripts by using the alternative 5′ splice site within exon 2, encoding the anti-apoptotic ...
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https://www.mdpi.com/1422-0067/17/12/2097
The Bcl-x gene was characterized as generating alternative transcripts by using the alternative 5′ splice site within exon 2, encoding the anti-apoptotic ...
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12
Alternative Splicing in Lung Cancer
https://www.jto.org/article/S1556-0864(15)32504-1/fulltext
An example that illustrates this relevance is the altered balance between Bcl-xL and Bcl-xS, two splice variants of the apoptosis regulator Bcl-x. Splice ...
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https://www.jto.org/article/S1556-0864(15)32504-1/fulltext
An example that illustrates this relevance is the altered balance between Bcl-xL and Bcl-xS, two splice variants of the apoptosis regulator Bcl-x. Splice ...
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13
The RNA-binding protein Sam68 modulates the alternative ...
https://rupress.org/jcb/article/176/7/929/44717/The-RNA-binding-protein-Sam68-modulates-the
Tyrosine phosphorylation of Sam68 by Fyn inverted this effect and favored the Bcl-x(L) splice site selection. A point mutation in the RNA- ...
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https://rupress.org/jcb/article/176/7/929/44717/The-RNA-binding-protein-Sam68-modulates-the
Tyrosine phosphorylation of Sam68 by Fyn inverted this effect and favored the Bcl-x(L) splice site selection. A point mutation in the RNA- ...
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14
Developmental consequences of alternative Bcl‐x splicing ...
https://onlinelibrary.wiley.com/doi/10.1111/j.1742-4658.2010.07554.x
› doi › j.1742-4658.2010....
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https://onlinelibrary.wiley.com/doi/10.1111/j.1742-4658.2010.07554.x
› doi › j.1742-4658.2010....
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15
The DNA Damage Response Pathway Regulates the ... - DOI
https://doi.org/10.1074%2Fjbc.M110.162644
Protein Synthesis. RNA Splicing. Signal Transduction. Bcl-x. Oxaliplatin ... Bcl-x is produced in two forms through the use of alternative 5′ splice sites.
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https://doi.org/10.1074%2Fjbc.M110.162644
Protein Synthesis. RNA Splicing. Signal Transduction. Bcl-x. Oxaliplatin ... Bcl-x is produced in two forms through the use of alternative 5′ splice sites.
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16
Regulation of alternative splicing and the case of Bcl-x
https://www.researchgate.net/publication/278668522_Regulation_of_alternative_splicing_and_the_case_of_Bcl-x
PDF | Almost every human pre-messenger RNA is alternatively spliced to produce mRNA variants that often encode proteins with distinct ...
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https://www.researchgate.net/publication/278668522_Regulation_of_alternative_splicing_and_the_case_of_Bcl-x
PDF | Almost every human pre-messenger RNA is alternatively spliced to produce mRNA variants that often encode proteins with distinct ...
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17
Modulation of the Apoptosis Gene Bcl-x ... - Semantic Scholar
https://www.semanticscholar.org/paper/Modulation-of-the-Apoptosis-Gene-Bcl-x-Function-Stevens-Oltean/4807d0c725a65bef441d6450c58dd9a273b9b4a0
Bcl-x, a member of the Bcl-2 family of proteins, is a mitochondrial ... An alternative splicing (AS) event in exon 2 of Bcl-x results in two ...
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https://www.semanticscholar.org/paper/Modulation-of-the-Apoptosis-Gene-Bcl-x-Function-Stevens-Oltean/4807d0c725a65bef441d6450c58dd9a273b9b4a0
Bcl-x, a member of the Bcl-2 family of proteins, is a mitochondrial ... An alternative splicing (AS) event in exon 2 of Bcl-x results in two ...
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18
Homoharringtonine regulates the alternative splicing of Bcl-x ...
https://link.springer.com/content/pdf/10.1186/s12906-018-2233-6.pdf
Keywords: Homoharringtonine, Alternative splicing, Bcl-x, Caspase 9, Protein phosphatase 1, Apoptosis. Background. Alternative splicing of mRNA is a key ...
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https://link.springer.com/content/pdf/10.1186/s12906-018-2233-6.pdf
Keywords: Homoharringtonine, Alternative splicing, Bcl-x, Caspase 9, Protein phosphatase 1, Apoptosis. Background. Alternative splicing of mRNA is a key ...
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19
Mediated Bcl-x and Fas/CD95 Alternative Splicing | PLOS ONE
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139812
We show that TCERG1 modulates Bcl-x alternative splicing during apoptosis and its activity in Bcl-x alternative splicing correlates with the ...
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139812
We show that TCERG1 modulates Bcl-x alternative splicing during apoptosis and its activity in Bcl-x alternative splicing correlates with the ...
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20
Regulation of Mcl-1 alternative splicing by hnRNP F, H1 and K ...
https://www.tandfonline.com/doi/full/10.1080/15476286.2018.1551692
]. Indeed the anti-apoptotic Mcl-1 and Bcl-X have been shown to be frequently amplified across a range of different human cancers, with the amplification ...
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https://www.tandfonline.com/doi/full/10.1080/15476286.2018.1551692
]. Indeed the anti-apoptotic Mcl-1 and Bcl-X have been shown to be frequently amplified across a range of different human cancers, with the amplification ...
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21
Regulation of Ich-1 pre-mRNA alternative splicing and ... - PNAS
https://www.pnas.org/doi/10.1073/pnas.95.16.9155
Most strikingly, alternative splicing of Bcl-x, Ced-4, and Ich-1 pre-mRNAs results in the formation of products that play opposite roles in apoptosis (1–3).
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https://www.pnas.org/doi/10.1073/pnas.95.16.9155
Most strikingly, alternative splicing of Bcl-x, Ced-4, and Ich-1 pre-mRNAs results in the formation of products that play opposite roles in apoptosis (1–3).
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22
Apoptosis regulator, Bcl-X (IPR013279) - InterPro entry
https://www.ebi.ac.uk/interpro/entry/interpro/IPR013279
Bcl-X(L), Bcl-X(S) and Bcl-Xb are three isoforms derived by alternative RNA splicing. Bcl-X(S) forms heterodimers with Bcl-2. Homologues of Bcl-X include ...
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https://www.ebi.ac.uk/interpro/entry/interpro/IPR013279
Bcl-X(L), Bcl-X(S) and Bcl-Xb are three isoforms derived by alternative RNA splicing. Bcl-X(S) forms heterodimers with Bcl-2. Homologues of Bcl-X include ...
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23
Biophysical characterisation of the Bcl-x pre-mRNA and ...
https://leicester.figshare.com/articles/journal_contribution/Biophysical_characterisation_of_the_Bcl-x_pre-mRNA_and_binding_specificity_of_the_ellipticine_derivative_GQC-05_Implication_for_alternative_splicing_regulation_/21121048
The BCL2L1 gene expresses two isoforms of Bcl-x protein via the use of either of two alternative 5' splice sites (5'ss) in exon 2.
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https://leicester.figshare.com/articles/journal_contribution/Biophysical_characterisation_of_the_Bcl-x_pre-mRNA_and_binding_specificity_of_the_ellipticine_derivative_GQC-05_Implication_for_alternative_splicing_regulation_/21121048
The BCL2L1 gene expresses two isoforms of Bcl-x protein via the use of either of two alternative 5' splice sites (5'ss) in exon 2.
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24
Alternative pre-mRNA splicing regulation in cancer
http://genesdev.cshlp.org/content/24/21/2343.full.pdf
isoform 5! splice site shifted splicing of Bcl-x to the Bcl- x(s) isoform, and was sufficient to induce apoptosis in a prostate cancer (PCa) cell line ...
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http://genesdev.cshlp.org/content/24/21/2343.full.pdf
isoform 5! splice site shifted splicing of Bcl-x to the Bcl- x(s) isoform, and was sufficient to induce apoptosis in a prostate cancer (PCa) cell line ...
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25
An Alternative Splicing Network Links Cell-Cycle Control to ...
https://core.ac.uk/download/pdf/82320989.pdf
of Bcl-x, Mcl1, and caspase-9 and alter splicing of other apoptotic transcripts. ... Reporter Assays for Bcl-x and Mcl1 Alternative Splicing.
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https://core.ac.uk/download/pdf/82320989.pdf
of Bcl-x, Mcl1, and caspase-9 and alter splicing of other apoptotic transcripts. ... Reporter Assays for Bcl-x and Mcl1 Alternative Splicing.
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26
Alternative Splicing of Apoptosis Genes Promotes Human T ...
https://www.biorxiv.org/content/10.1101/2022.06.17.496561v1.full.pdf
Like. FAS, the gene encoding Bcl-x is alternatively spliced to produce two isoforms: Bcl-xS, which promotes the activity of Bax and apoptosis, ...
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https://www.biorxiv.org/content/10.1101/2022.06.17.496561v1.full.pdf
Like. FAS, the gene encoding Bcl-x is alternatively spliced to produce two isoforms: Bcl-xS, which promotes the activity of Bax and apoptosis, ...
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27
Modification of Bcl-x and Mcl-1 Pre-mRNA Splicing Using ...
https://cdr.lib.unc.edu/downloads/bv73c073m?locale=en
Figure 2.5 Bcl-x SSO does not affect Mcl-1 alternative pre-mRNA splicing. ....................... 80. Figure 2.6 Schematic depiction of the preparation of ...
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https://cdr.lib.unc.edu/downloads/bv73c073m?locale=en
Figure 2.5 Bcl-x SSO does not affect Mcl-1 alternative pre-mRNA splicing. ....................... 80. Figure 2.6 Schematic depiction of the preparation of ...
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28
Regulation of Ich-1 pre-mRNA alternative splicing and ...
https://labs.feinberg.northwestern.edu/wu/docs/publications/Jiang_Ich1PNAS98.pdf
Most strikingly, alternative splicing of. Bcl-x, Ced-4, and Ich-1 pre-mRNAs results in the formation of products that play opposite roles in apoptosis (1–3) ...
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https://labs.feinberg.northwestern.edu/wu/docs/publications/Jiang_Ich1PNAS98.pdf
Most strikingly, alternative splicing of. Bcl-x, Ced-4, and Ich-1 pre-mRNAs results in the formation of products that play opposite roles in apoptosis (1–3) ...
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29
bcl-X Protein | Profiles RNS
https://profiles.umassmed.edu/display/125368
Two major isoforms of the protein exist due to ALTERNATIVE SPLICING of the BCL2L1 mRNA and are referred to as Bcl-XS and Bcl-XL.
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https://profiles.umassmed.edu/display/125368
Two major isoforms of the protein exist due to ALTERNATIVE SPLICING of the BCL2L1 mRNA and are referred to as Bcl-XS and Bcl-XL.
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30
Specific G-quadruplex ligands modulate the ... - Strathprints
https://strathprints.strath.ac.uk/62617/7/Weldon_etal_NAR_2017_Specific_G_quadruplex_ligands_modulate_the_alternative_splicing.pdf
alternative splicing of Bcl-X. Carika Weldon1, Justine G. Dacanay1, ... Certain putative G4 ligands affect Bcl-X splice site selection.
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https://strathprints.strath.ac.uk/62617/7/Weldon_etal_NAR_2017_Specific_G_quadruplex_ligands_modulate_the_alternative_splicing.pdf
alternative splicing of Bcl-X. Carika Weldon1, Justine G. Dacanay1, ... Certain putative G4 ligands affect Bcl-X splice site selection.
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31
Aberrant Bcl-x splicing in cancer: from molecular ... - ProQuest
https://search.proquest.com/openview/3d726cf9e8fbe6122d3784a30bb0e131/1?pq-origsite=gscholar&cbl=105475
Abstract. Bcl-x pre-mRNA splicing serves as a typical example to study the impact of alternative splicing in the modulation of cell death. Dysregulation of ...
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https://search.proquest.com/openview/3d726cf9e8fbe6122d3784a30bb0e131/1?pq-origsite=gscholar&cbl=105475
Abstract. Bcl-x pre-mRNA splicing serves as a typical example to study the impact of alternative splicing in the modulation of cell death. Dysregulation of ...
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32
Regulation of alternative splicing of Bcl-x by BC200 ...
https://cyberleninka.org/article/n/1368805.pdf
Regulation of alternative splicing of Bcl-x by BC200 contributes to breast cancer pathogenesis. R Singh1, SC Gupta1,7, W-X Peng1,2, N Zhou3, ...
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https://cyberleninka.org/article/n/1368805.pdf
Regulation of alternative splicing of Bcl-x by BC200 contributes to breast cancer pathogenesis. R Singh1, SC Gupta1,7, W-X Peng1,2, N Zhou3, ...
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33
Figure 3 | Modulation of Bcl-x Alternative Splicing ... - Hindawi
https://www.hindawi.com/journals/bmri/2016/7478650/fig3/
SSO induced Bcl-x splice-switching in human HSCs. RT-PCR analysis of Bcl-x mRNA from cells transfected with control and Bcl-x SSO was performed 24 h after ...
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https://www.hindawi.com/journals/bmri/2016/7478650/fig3/
SSO induced Bcl-x splice-switching in human HSCs. RT-PCR analysis of Bcl-x mRNA from cells transfected with control and Bcl-x SSO was performed 24 h after ...
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34
The Importance of Bcl-xL in the Survival of Human RPE Cells
https://iovs.arvojournals.org/article.aspx?articleid=2184050
RNA and protein were harvested at various time points after transfection. ... 19 Bcl-xL SSO, spanning the proximal 5′ splice site of Bcl-x pre-mRNA of ...
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https://iovs.arvojournals.org/article.aspx?articleid=2184050
RNA and protein were harvested at various time points after transfection. ... 19 Bcl-xL SSO, spanning the proximal 5′ splice site of Bcl-x pre-mRNA of ...
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35
Imatinib regulates the alternative pre-mRNA splicing of Bcl-x ...
https://sciendo.com/pdf/10.5372/1905-7415.0603.066
Results: Imatinib regulated the alternative splicing in the Bcl-x gene in the K562 cells. In addition, we found.
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https://sciendo.com/pdf/10.5372/1905-7415.0603.066
Results: Imatinib regulated the alternative splicing in the Bcl-x gene in the K562 cells. In addition, we found.
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36
signaling control of splicing proteins
https://www.med.upenn.edu/lynchlab/publications/11-TIBS-Heyd-Lynch.pdf
X. Y. TiBS. Figure I. Reciprocal regulation of alternative splicing by activator and ... BCLX gene to favor the generation of the proapoptotic Xs.
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https://www.med.upenn.edu/lynchlab/publications/11-TIBS-Heyd-Lynch.pdf
X. Y. TiBS. Figure I. Reciprocal regulation of alternative splicing by activator and ... BCLX gene to favor the generation of the proapoptotic Xs.
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37
RNA-binding protein Sam68 modulates the ... - Agris (FAO)
https://agris.fao.org/agris-search/search.do?recordID=US201300762631
We demonstrate that Sam68 binds the mRNA for Bcl-x and affects its alternative splicing. Depletion of Sam68 by RNA interference caused accumulation of ...
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https://agris.fao.org/agris-search/search.do?recordID=US201300762631
We demonstrate that Sam68 binds the mRNA for Bcl-x and affects its alternative splicing. Depletion of Sam68 by RNA interference caused accumulation of ...
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38
Medline ® Abstract for Reference 9 of 'Pathobiology of ...
https://www.uptodate.com/contents/pathobiology-of-follicular-lymphoma/abstract/9
Alternative splicing results in two distinct bcl-x mRNAs. The protein product of the larger mRNA, bcl-xL, is similar in size and predicted structure to ...
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https://www.uptodate.com/contents/pathobiology-of-follicular-lymphoma/abstract/9
Alternative splicing results in two distinct bcl-x mRNAs. The protein product of the larger mRNA, bcl-xL, is similar in size and predicted structure to ...
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39
BCL2L1 (BCL2-like 1)
https://atlasgeneticsoncology.org/gene/129/bcl2l1-(bcl2-like-1)
Two major isoforms exist due to alternative splicing of the BCL2L1 mRNA: Bcl-xS and Bcl-xL. The bcl-x promoter contains consensus motifs for ...
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https://atlasgeneticsoncology.org/gene/129/bcl2l1-(bcl2-like-1)
Two major isoforms exist due to alternative splicing of the BCL2L1 mRNA: Bcl-xS and Bcl-xL. The bcl-x promoter contains consensus motifs for ...
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40
Regulation of alternative splicing by G-quadruplexes
https://app.dimensions.ai/details/grant/grant.7388859
Importantly, the effects of each one on Bcl-X splicing are similar in nuclear extracts with purified pre-mRNA and in cells, showing that the molecules ...
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https://app.dimensions.ai/details/grant/grant.7388859
Importantly, the effects of each one on Bcl-X splicing are similar in nuclear extracts with purified pre-mRNA and in cells, showing that the molecules ...
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41
BCL-2 family isoforms in apoptosis and cancer - NOVA
https://nova.newcastle.edu.au/vital/access/services/Download/uon:36748/ATTACHMENT02
The two major isoforms arise from alternative splicing of BCL-X; splicing at the distal end of the 5′ splice site within the first coding exon.
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https://nova.newcastle.edu.au/vital/access/services/Download/uon:36748/ATTACHMENT02
The two major isoforms arise from alternative splicing of BCL-X; splicing at the distal end of the 5′ splice site within the first coding exon.
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42
bcl-x, a bcl-2-related gene that functions as a dominant ...
https://deepblue.lib.umich.edu/handle/2027.42/30629
... of bcl-x, a bcl-2-related gene that can function as a bcl-2-independent regulator of programed cell death (apoptosis). Alternative splicing results in ...
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https://deepblue.lib.umich.edu/handle/2027.42/30629
... of bcl-x, a bcl-2-related gene that can function as a bcl-2-independent regulator of programed cell death (apoptosis). Alternative splicing results in ...
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43
Chalfant Lab Research
http://www.people.vcu.edu/~cechalfant/research.htm
Project 1: Ceramide regulation of the alternative splicing of Bcl-x pre-mRNA (ongoing for 5 years). The long-term objectives of this project focus on the ...
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http://www.people.vcu.edu/~cechalfant/research.htm
Project 1: Ceramide regulation of the alternative splicing of Bcl-x pre-mRNA (ongoing for 5 years). The long-term objectives of this project focus on the ...
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44
Bcl-x Products: R&D Systems
https://www.rndsystems.com/target/bcl-x
Bcl-x is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. Alternative splicing results in two distinct ...
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https://www.rndsystems.com/target/bcl-x
Bcl-x is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. Alternative splicing results in two distinct ...
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45
Alternative splicing of apoptosis genes promotes human T cell ...
https://elifesciences.org/articles/80953
Therefore, regulating the isoform expression of apoptotic molecules such as FAS, Bcl-x, and caspase-9 is a critical mechanism cells use to ...
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https://elifesciences.org/articles/80953
Therefore, regulating the isoform expression of apoptotic molecules such as FAS, Bcl-x, and caspase-9 is a critical mechanism cells use to ...
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46
Specific G-quadruplex ligands modulate the ... - Labordoc - ILO
https://labordoc.ilo.org/discovery/fulldisplay?docid=cdi_oup_primary_10_1093_nar_gkx1122&context=PC&vid=41ILO_INST:41ILO_V1&lang=en&search_scope=MyInst_and_CI&adaptor=Primo%20Central&tab=Everything&query=sub%2Cexact%2CAlternative%20Splicing%20
We have shown previously that two G4s form in Bcl-X pre-mRNA, one close to each of the two alternative 5′SS. If these G4s affect splicing but are in ...
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https://labordoc.ilo.org/discovery/fulldisplay?docid=cdi_oup_primary_10_1093_nar_gkx1122&context=PC&vid=41ILO_INST:41ILO_V1&lang=en&search_scope=MyInst_and_CI&adaptor=Primo%20Central&tab=Everything&query=sub%2Cexact%2CAlternative%20Splicing%20
We have shown previously that two G4s form in Bcl-X pre-mRNA, one close to each of the two alternative 5′SS. If these G4s affect splicing but are in ...
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47
Dissecting the role of alternative splicing in the regulatio...
https://journals.lww.com/jbioxresearch/Fulltext/2020/09000/Dissecting_the_role_of_alternative_splicing_in_the.4.aspx
Alternative splicing plays a pivotal role in the posttranscriptional ... BimS and BimEL are bound to the antiapoptotic proteins Bcl-2 and Bcl-x(L) to ...
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https://journals.lww.com/jbioxresearch/Fulltext/2020/09000/Dissecting_the_role_of_alternative_splicing_in_the.4.aspx
Alternative splicing plays a pivotal role in the posttranscriptional ... BimS and BimEL are bound to the antiapoptotic proteins Bcl-2 and Bcl-x(L) to ...
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48
mediated BCL-X alternative splicing and apoptosis
https://art.torvergata.it/retrieve/handle/2108/93289/282240/EMBO%20Reports%202014.pdf
tion with a direct impact on cell survival. Keywords alternative splicing; apoptosis; BCL-X; FBI-1; SAM68. Subject Categories RNA Biology; ...
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https://art.torvergata.it/retrieve/handle/2108/93289/282240/EMBO%20Reports%202014.pdf
tion with a direct impact on cell survival. Keywords alternative splicing; apoptosis; BCL-X; FBI-1; SAM68. Subject Categories RNA Biology; ...
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49
Apoptosis regulator proteins, Bcl-2 family BH motifs signatures ...
https://prosite.expasy.org/doc/PS01258
Two isoforms of bcl-2 (α and β) are generated by alternative splicing. ... While the longer product (Bcl-x(L)) can protect a growth-factor-dependent cell ...
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https://prosite.expasy.org/doc/PS01258
Two isoforms of bcl-2 (α and β) are generated by alternative splicing. ... While the longer product (Bcl-x(L)) can protect a growth-factor-dependent cell ...
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50
Regulation of alternative splicing and the case of Bcl-x
http://www.pjbmb.org.pk/images/PJBMBArchive/2015/PJBMB_48_2_Jun_2015/1.pdf
regulate alternative splicing decisions. Keywords: Pre-mRNA, alternative splicing, Bcl-x,. Received: December 10, 2014 Accepted: March 21, 2015.
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http://www.pjbmb.org.pk/images/PJBMBArchive/2015/PJBMB_48_2_Jun_2015/1.pdf
regulate alternative splicing decisions. Keywords: Pre-mRNA, alternative splicing, Bcl-x,. Received: December 10, 2014 Accepted: March 21, 2015.
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51
Bcl-x Products | Bio-Techne
https://www.bio-techne.com/t/bcl-x
Alternative splicing results in two distinct Bcl-x isoforms. Bcl-xL (long) is an anti-apoptotic protein that prevents release of Cytochromec from the ...
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https://www.bio-techne.com/t/bcl-x
Alternative splicing results in two distinct Bcl-x isoforms. Bcl-xL (long) is an anti-apoptotic protein that prevents release of Cytochromec from the ...
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52
Vials: Visualizing Alternative Splicing of Genes - VCG Harvard
https://vcg.seas.harvard.edu/publications/vials-visualizing-alternative-splicing-of-genes
Alternative splicing is a process by which the same DNA sequence is used to assemble different proteins, called protein isoforms. Alternative splicing works ...
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https://vcg.seas.harvard.edu/publications/vials-visualizing-alternative-splicing-of-genes
Alternative splicing is a process by which the same DNA sequence is used to assemble different proteins, called protein isoforms. Alternative splicing works ...
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53
Chasing Alternative Splicing in Cancer Simplified Full length ...
https://www.youtube.com/watch?v=e3sxKQ76Njs
Dec 4, 2017
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https://www.youtube.com/watch?v=e3sxKQ76Njs
Dec 4, 2017
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54
Alternative splicing - YouTube
https://www.youtube.com/watch?v=GT_jmOQH4Zg
Shomu's Biology
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https://www.youtube.com/watch?v=GT_jmOQH4Zg
Shomu's Biology
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55
Experimentally Evaluating Alternative RNA Splicing Variants
https://www.youtube.com/watch?v=dzTQX4w86w0
VCU Libraries
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https://www.youtube.com/watch?v=dzTQX4w86w0
VCU Libraries
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56
Apoptosis & BCL-2 Animation | XVIVO
https://xvivo.com/blog/apoptosis-bcl-2/
Abbvie and Genentech are developing a new medication for the selective inhibition of BCL-2, a key regulator of cellular apoptosis.
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https://xvivo.com/blog/apoptosis-bcl-2/
Abbvie and Genentech are developing a new medication for the selective inhibition of BCL-2, a key regulator of cellular apoptosis.
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57
9. mRNA Splicing and Alternative Splicing - IU Pressbooks
https://iu.pressbooks.pub/iul211smehta/chapter/mrna-splicing-and-alternative-splicing/
Draw splicing diagrams to show alternative splicing patterns. ... consisting of almost 0.1% of the human genome or about 1.5% of the entire X chromosome.
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https://iu.pressbooks.pub/iul211smehta/chapter/mrna-splicing-and-alternative-splicing/
Draw splicing diagrams to show alternative splicing patterns. ... consisting of almost 0.1% of the human genome or about 1.5% of the entire X chromosome.
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58
mRNA Splicing and Alternative Splicing - LabXchange
https://www.labxchange.org/library/items/lb:LabXchange:e7f42b2e:video:1?source=%2Flibrary%2Fbooks%2Flx-book%3A50486a61-d685-4003-981d-2f6a87ec8fb1%3Fsource%3D%2Flibrary%2Fclusters%2Flx-cluster%3AAPBio
› library › items › lx-cluste...
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https://www.labxchange.org/library/items/lb:LabXchange:e7f42b2e:video:1?source=%2Flibrary%2Fbooks%2Flx-book%3A50486a61-d685-4003-981d-2f6a87ec8fb1%3Fsource%3D%2Flibrary%2Fclusters%2Flx-cluster%3AAPBio
› library › items › lx-cluste...
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59
Alternative splicing ( mechanism and its regulation ) - YouTube
https://www.youtube.com/watch?v=JhP3kHVmicw
Animated biology With arpan
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https://www.youtube.com/watch?v=JhP3kHVmicw
Animated biology With arpan
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60
Epigenetic Regulation and Epigenomics
https://books.google.com/books?id=jzU7wpL0I40C&pg=PA853&lpg=PA853&dq=alternative+splicing+bcl+x&source=bl&ots=C_vGmvYCiK&sig=ACfU3U2MjJeU70EcCx9nul3X2MowlR8nKg&hl=en&sa=X&ved=2ahUKEwjxx4aBjNX7AhXhTaQEHe8PAskQ6AF6BQj-ARAD
Bcl-x gene Bcl-x pre-mRNA 1 Transcription 3 2 Fig.2 Regulation of alternative splicing by antisense RNA drug [15]. The three possible splicing events on the ...
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https://books.google.com/books?id=jzU7wpL0I40C&pg=PA853&lpg=PA853&dq=alternative+splicing+bcl+x&source=bl&ots=C_vGmvYCiK&sig=ACfU3U2MjJeU70EcCx9nul3X2MowlR8nKg&hl=en&sa=X&ved=2ahUKEwjxx4aBjNX7AhXhTaQEHe8PAskQ6AF6BQj-ARAD
Bcl-x gene Bcl-x pre-mRNA 1 Transcription 3 2 Fig.2 Regulation of alternative splicing by antisense RNA drug [15]. The three possible splicing events on the ...
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61
Regulation of Alternative Splicing - Page 237 - Google Books Result
https://books.google.com/books?id=C4zqCAAAQBAJ&pg=PA237&lpg=PA237&dq=alternative+splicing+bcl+x&source=bl&ots=o01HInhiV6&sig=ACfU3U3R9dvQFvqTYvMG3nTq8F5KFkVZYQ&hl=en&sa=X&ved=2ahUKEwjxx4aBjNX7AhXhTaQEHe8PAskQ6AF6BQjzARAD
Ishigaki Y, Li X, Serin G, Maquat LE (2001) Evidence for a pioneer round of mRNA ... Mabon SA, Misteli T (2001) Correction of alternative splicing of tau in ...
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https://books.google.com/books?id=C4zqCAAAQBAJ&pg=PA237&lpg=PA237&dq=alternative+splicing+bcl+x&source=bl&ots=o01HInhiV6&sig=ACfU3U3R9dvQFvqTYvMG3nTq8F5KFkVZYQ&hl=en&sa=X&ved=2ahUKEwjxx4aBjNX7AhXhTaQEHe8PAskQ6AF6BQjzARAD
Ishigaki Y, Li X, Serin G, Maquat LE (2001) Evidence for a pioneer round of mRNA ... Mabon SA, Misteli T (2001) Correction of alternative splicing of tau in ...
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62
Advances in Immunology - Page 163 - Google Books Result
https://books.google.com/books?id=FEw5yLHSelcC&pg=PA163&lpg=PA163&dq=alternative+splicing+bcl+x&source=bl&ots=I8WIW7Ywnf&sig=ACfU3U3XgagU7civP6dbb-slCwStaPsgtg&hl=en&sa=X&ved=2ahUKEwjxx4aBjNX7AhXhTaQEHe8PAskQ6AF6BQj1ARAD
Bcl-2 may act as a survival signal for positive selection of T and B cells (Strasser ... proteins by alternative splicing, Bcl-X. (long) and Bcl-Xs (short).
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https://books.google.com/books?id=FEw5yLHSelcC&pg=PA163&lpg=PA163&dq=alternative+splicing+bcl+x&source=bl&ots=I8WIW7Ywnf&sig=ACfU3U3XgagU7civP6dbb-slCwStaPsgtg&hl=en&sa=X&ved=2ahUKEwjxx4aBjNX7AhXhTaQEHe8PAskQ6AF6BQj1ARAD
Bcl-2 may act as a survival signal for positive selection of T and B cells (Strasser ... proteins by alternative splicing, Bcl-X. (long) and Bcl-Xs (short).
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63
Molecular Mechanisms in Cancer - Page 17 - Google Books Result
https://books.google.com/books?id=n8CFEAAAQBAJ&pg=PA17&lpg=PA17&dq=alternative+splicing+bcl+x&source=bl&ots=zvnVQDxoTV&sig=ACfU3U0mAaqm2caJqOCXnsybL5j48GfMBQ&hl=en&sa=X&ved=2ahUKEwjxx4aBjNX7AhXhTaQEHe8PAskQ6AF6BQj0ARAD
... in cancers are affected by alternative splicing (Figure 16). ... U2AF65 and regulate the alternative splicing of the AR and BCL-x genes, respectively.
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https://books.google.com/books?id=n8CFEAAAQBAJ&pg=PA17&lpg=PA17&dq=alternative+splicing+bcl+x&source=bl&ots=zvnVQDxoTV&sig=ACfU3U0mAaqm2caJqOCXnsybL5j48GfMBQ&hl=en&sa=X&ved=2ahUKEwjxx4aBjNX7AhXhTaQEHe8PAskQ6AF6BQj0ARAD
... in cancers are affected by alternative splicing (Figure 16). ... U2AF65 and regulate the alternative splicing of the AR and BCL-x genes, respectively.
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64
Post-transcriptional Regulation through Long Non-coding RNAs ...
https://books.google.com/books?id=qUY-EAAAQBAJ&pg=PA86&lpg=PA86&dq=alternative+splicing+bcl+x&source=bl&ots=A62TF4-Vjr&sig=ACfU3U3OB977eRzmiFOCjghgIe-CIR_IFg&hl=en&sa=X&ved=2ahUKEwjxx4aBjNX7AhXhTaQEHe8PAskQ6AF6BQj2ARAD
Ladd, A.N. CUG-BP, Elav-like family (CELF)-mediated alternative splicing ... Bordi, M.; Di Biasio, V.; Sette, C. Regulation of BCL-X splicing reveals a role ...
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https://books.google.com/books?id=qUY-EAAAQBAJ&pg=PA86&lpg=PA86&dq=alternative+splicing+bcl+x&source=bl&ots=A62TF4-Vjr&sig=ACfU3U3OB977eRzmiFOCjghgIe-CIR_IFg&hl=en&sa=X&ved=2ahUKEwjxx4aBjNX7AhXhTaQEHe8PAskQ6AF6BQj2ARAD
Ladd, A.N. CUG-BP, Elav-like family (CELF)-mediated alternative splicing ... Bordi, M.; Di Biasio, V.; Sette, C. Regulation of BCL-X splicing reveals a role ...
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65
Immunopharmacology Reviews Volume 2
https://books.google.com/books?id=ZyPnBwAAQBAJ&pg=PA403&lpg=PA403&dq=alternative+splicing+bcl+x&source=bl&ots=AgK5opCuo9&sig=ACfU3U38_4IE9YUJRM0flc1jpCORYBIBMQ&hl=en&sa=X&ved=2ahUKEwjxx4aBjNX7AhXhTaQEHe8PAskQ6AF6BQjyARAD
rescued by bcl-2, whereas ciliary neurotropic factor (CNTF)-dependent ciliary neurons were not ... Alternative splicing results in two distinct bcl-X mRNAs.
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https://books.google.com/books?id=ZyPnBwAAQBAJ&pg=PA403&lpg=PA403&dq=alternative+splicing+bcl+x&source=bl&ots=AgK5opCuo9&sig=ACfU3U38_4IE9YUJRM0flc1jpCORYBIBMQ&hl=en&sa=X&ved=2ahUKEwjxx4aBjNX7AhXhTaQEHe8PAskQ6AF6BQjyARAD
rescued by bcl-2, whereas ciliary neurotropic factor (CNTF)-dependent ciliary neurons were not ... Alternative splicing results in two distinct bcl-X mRNAs.
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