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Google Keyword Rankings for : dca pulmonary hypertension
1
Dichloroacetate (DCA) for the Treatment of Pulmonary Arterial ...
https://clinicaltrials.gov/ct2/show/NCT01083524
Brief Summary: Hypothesis: The small molecule and metabolic modulator Dichloroacetate (DCA) is safe, tolerated as a potential therapy in ...
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https://clinicaltrials.gov/ct2/show/NCT01083524
Brief Summary: Hypothesis: The small molecule and metabolic modulator Dichloroacetate (DCA) is safe, tolerated as a potential therapy in ...
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2
Dichloroacetate prevents and reverses pulmonary ... - PubMed
https://pubmed.ncbi.nlm.nih.gov/15375007/
We show that dichloroacetate (DCA), a metabolic modulator that increases mitochondrial oxidative phosphorylation, prevents and reverses established ...
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https://pubmed.ncbi.nlm.nih.gov/15375007/
We show that dichloroacetate (DCA), a metabolic modulator that increases mitochondrial oxidative phosphorylation, prevents and reverses established ...
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3
Dichloroacetate Prevents and Reverses Pulmonary ...
https://www.ahajournals.org/doi/10.1161/01.res.0000145360.16770.9f
We show that DCA can both prevent and reverse established pulmonary vascular remodeling in a common model of PAH and thus improve hemodynamics, RVH, and ...
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https://www.ahajournals.org/doi/10.1161/01.res.0000145360.16770.9f
We show that DCA can both prevent and reverse established pulmonary vascular remodeling in a common model of PAH and thus improve hemodynamics, RVH, and ...
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4
Inhibition of pyruvate dehydrogenase kinase improves ...
https://www.science.org/doi/10.1126/scitranslmed.aao4583
PDK inhibition by DCA increases PDH activity and oxygen consumption in isolated perfused/ventilated PAH lungs, consistent with improvement in mitochondrial ...
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https://www.science.org/doi/10.1126/scitranslmed.aao4583
PDK inhibition by DCA increases PDH activity and oxygen consumption in isolated perfused/ventilated PAH lungs, consistent with improvement in mitochondrial ...
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5
Promising mitochondria-targeting drug for PAH - Nature
https://www.nature.com/articles/nrcardio.2017.188
A new study now shows that dichloroacetate (DCA), an inhibitor of the mitochondrial enzyme pyruvate dehydrogenase kinase (PDK), improves ...
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https://www.nature.com/articles/nrcardio.2017.188
A new study now shows that dichloroacetate (DCA), an inhibitor of the mitochondrial enzyme pyruvate dehydrogenase kinase (PDK), improves ...
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6
PAH Patient Study Shows Affordable Generic DCA Could ...
https://pulmonaryhypertensionnews.com/columns/pah-patient-study-shows-affordable-generic-dca-could-help-treatment/
The cost to treat pulmonary arterial hypertension (PAH) is often exceedingly high, costing more than $200,000 annually.
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https://pulmonaryhypertensionnews.com/columns/pah-patient-study-shows-affordable-generic-dca-could-help-treatment/
The cost to treat pulmonary arterial hypertension (PAH) is often exceedingly high, costing more than $200,000 annually.
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7
Dichloroacetate treatment partially regresses established ...
https://onlinelibrary.wiley.com/doi/abs/10.1096/fj.09-131664
... patients with idiopathic pulmonary arterial hypertension (IPAH) and in ... DCA partially reversed PAH in SM22-5- HTT+ mice by decreasing ...
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https://onlinelibrary.wiley.com/doi/abs/10.1096/fj.09-131664
... patients with idiopathic pulmonary arterial hypertension (IPAH) and in ... DCA partially reversed PAH in SM22-5- HTT+ mice by decreasing ...
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8
FDCA ameliorates SU5416/hypoxia-induced PASMC ...
https://www.dovepress.com/fasudil-dichloroacetate-alleviates-su5416hypoxia-induced-pulmonary-art-peer-reviewed-fulltext-article-DDDT
Pulmonary arterial hypertension (PAH), a progressive lung vascular disease with a poor prognosis and limited therapeutic options, is ...
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https://www.dovepress.com/fasudil-dichloroacetate-alleviates-su5416hypoxia-induced-pulmonary-art-peer-reviewed-fulltext-article-DDDT
Pulmonary arterial hypertension (PAH), a progressive lung vascular disease with a poor prognosis and limited therapeutic options, is ...
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9
Dichloroacetate prevents but not reverses the formation of ...
https://www.spandidos-publications.com/10.3892/mmr.2014.2432
23±2.2 mmHg; RV/LV+IVS, 43±3.3 vs. 28±2.2%; P<0.05). The preventive treatment with DCA significantly repressed the elevation of pulmonary ...
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https://www.spandidos-publications.com/10.3892/mmr.2014.2432
23±2.2 mmHg; RV/LV+IVS, 43±3.3 vs. 28±2.2%; P<0.05). The preventive treatment with DCA significantly repressed the elevation of pulmonary ...
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10
DCA-PAH Study - Health Research Authority
https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/dca-pah-study/
We are conducting a study of a new medicine, dichloroacetate (DCA), for pulmonary hypertension. This medicine affects the way in which cells divide and the ...
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https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/dca-pah-study/
We are conducting a study of a new medicine, dichloroacetate (DCA), for pulmonary hypertension. This medicine affects the way in which cells divide and the ...
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11
Strategizing Drug Therapies in Pulmonary Hypertension for ...
https://www.mdpi.com/1424-8247/15/10/1242/pdf
A rarer variant of PH is pulmonary arterial hypertension (PAH), ... A 16 week phase I trial with DCA in PAH patients (n = 20) demonstrated.
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https://www.mdpi.com/1424-8247/15/10/1242/pdf
A rarer variant of PH is pulmonary arterial hypertension (PAH), ... A 16 week phase I trial with DCA in PAH patients (n = 20) demonstrated.
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12
The Metabolic Basis of Pulmonary Arterial Hypertension
https://www.cell.com/cell-metabolism/pdf/S1550-4131(14)00010-2.pdf
Pulmonary arterial hypertension (PAH) is a vascular remodeling ... have increased medial thickening, which is reversed by DCA (bottom).
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https://www.cell.com/cell-metabolism/pdf/S1550-4131(14)00010-2.pdf
Pulmonary arterial hypertension (PAH) is a vascular remodeling ... have increased medial thickening, which is reversed by DCA (bottom).
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13
Metabolism alteration in pulmonary hypertension. DCA ...
https://www.researchgate.net/figure/Metabolism-alteration-in-pulmonary-hypertension-DCA-dichloroacetate-ETC-electron_fig2_341596619
Pulmonary hypertension (PH) is defined as increased mean pulmonary artery pressure (mPAP) above 25 mmHg, measured at rest by right heart catheterization. The ...
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https://www.researchgate.net/figure/Metabolism-alteration-in-pulmonary-hypertension-DCA-dichloroacetate-ETC-electron_fig2_341596619
Pulmonary hypertension (PH) is defined as increased mean pulmonary artery pressure (mPAP) above 25 mmHg, measured at rest by right heart catheterization. The ...
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14
Targeting mitochondria in pulmonary hypertension
https://wms-site.com/mitochondria-in-press-and-media/706-targeting-mitochondria-in-pulmonary-hypertension
In this week's issue of Science Translational Medicine, the investigators showed that the generic drug, Dichloroacetate (DCA), can decrease the blood pressure ...
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https://wms-site.com/mitochondria-in-press-and-media/706-targeting-mitochondria-in-pulmonary-hypertension
In this week's issue of Science Translational Medicine, the investigators showed that the generic drug, Dichloroacetate (DCA), can decrease the blood pressure ...
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15
Emerging therapeutics in pulmonary hypertension
https://journals.physiology.org/doi/10.1152/ajplung.00259.2017
Pulmonary hypertension (PH) is a progressive and often fatal illness presenting with nonspecific symptoms of dyspnea, lower extremity edema, and exercise ...
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https://journals.physiology.org/doi/10.1152/ajplung.00259.2017
Pulmonary hypertension (PH) is a progressive and often fatal illness presenting with nonspecific symptoms of dyspnea, lower extremity edema, and exercise ...
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16
New Therapeutic Targets in Pulmonary Arterial Hypertension
https://www.medscape.com/viewarticle/778724_3
Current therapeutic strategies are mainly designed to induce relaxation of the pulmonary arteries, not to improve vascular remodeling that characterizes PAH ...
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https://www.medscape.com/viewarticle/778724_3
Current therapeutic strategies are mainly designed to induce relaxation of the pulmonary arteries, not to improve vascular remodeling that characterizes PAH ...
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17
New hope for pulmonary hypertension thanks to old drug
https://www.ctvnews.ca/health/new-hope-for-pulmonary-hypertension-thanks-to-old-drug-1.3648568
Investigators report that the drug Dichloroacetate (DCA), a generic drug that costs a few cents per dose, can decrease the blood pressure in the ...
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https://www.ctvnews.ca/health/new-hope-for-pulmonary-hypertension-thanks-to-old-drug-1.3648568
Investigators report that the drug Dichloroacetate (DCA), a generic drug that costs a few cents per dose, can decrease the blood pressure in the ...
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18
American Journal of Respiratory and Critical Care Medicine
https://www.atsjournals.org/doi/full/10.1164/rccm.201108-1562OC
Rationale: Pulmonary arterial hypertension (PAH) is a proliferative arteriopathy associated with glucose transporter-1 (Glut1) up-regulation ...
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https://www.atsjournals.org/doi/full/10.1164/rccm.201108-1562OC
Rationale: Pulmonary arterial hypertension (PAH) is a proliferative arteriopathy associated with glucose transporter-1 (Glut1) up-regulation ...
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19
Potential treatment for pulmonary hypertension discovered
https://www.sciencedaily.com/releases/2010/08/100811141106.htm
By using dichloroacetate (DCA) or Trimetazidine (TMZ), mitochondria targeted drugs, the activity of the mitochondria increases which helps ...
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https://www.sciencedaily.com/releases/2010/08/100811141106.htm
By using dichloroacetate (DCA) or Trimetazidine (TMZ), mitochondria targeted drugs, the activity of the mitochondria increases which helps ...
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20
Drug repositioning in pulmonary arterial hypertension
https://journals.sagepub.com/doi/10.1177/2045894019832226
In this open label study, 20 patients with PAH who were stable on PAH-approved therapies were given varied doses of DCA. At the highest dose of DCA administered ...
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https://journals.sagepub.com/doi/10.1177/2045894019832226
In this open label study, 20 patients with PAH who were stable on PAH-approved therapies were given varied doses of DCA. At the highest dose of DCA administered ...
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21
Focus on Early Events: Pathogenesis of Pulmonary Arterial ...
https://www.liebertpub.com/doi/10.1089/ars.2018.7673
Pulmonary arterial hypertension (PAH)/pulmonary hypertension (PH) is a fatal disease characterized by pathologic vascular remodeling, leading to ...
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https://www.liebertpub.com/doi/10.1089/ars.2018.7673
Pulmonary arterial hypertension (PAH)/pulmonary hypertension (PH) is a fatal disease characterized by pathologic vascular remodeling, leading to ...
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22
Old drug gives new hope for pulmonary hypertension patients
https://www.ualberta.ca/folio/2017/11/old-drug-gives-new-hope-for-pulmonary-hypertension-patients.html
In a recent clinical trial, UAlberta medical researchers found that dichloroacetate (DCA)-typically used to treat mitochondrial disease- ...
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https://www.ualberta.ca/folio/2017/11/old-drug-gives-new-hope-for-pulmonary-hypertension-patients.html
In a recent clinical trial, UAlberta medical researchers found that dichloroacetate (DCA)-typically used to treat mitochondrial disease- ...
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23
Molecular pathogenesis of pulmonary arterial hypertension - JCI
https://www.jci.org/articles/view/60658
Pulmonary arterial hypertension (PAH) is diagnosed by an elevation in mean pulmonary arterial (PA) pressure above 25 mmHg at rest or 30 mmHg with exercise.
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https://www.jci.org/articles/view/60658
Pulmonary arterial hypertension (PAH) is diagnosed by an elevation in mean pulmonary arterial (PA) pressure above 25 mmHg at rest or 30 mmHg with exercise.
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24
Epigenetic metabolic reprogramming of right ventricular
https://pureportal.strath.ac.uk/files/103536579/Tian_etal_CR_2020_Epigenetic_metabolic_reprogramming_of_right_ventricular_fibroblasts.pdf
fibroblasts in pulmonary arterial hypertension: A pyruvate ... dichloroacetate (DCA), restores mitochondrial glucose metabolism and inhibits cell.
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https://pureportal.strath.ac.uk/files/103536579/Tian_etal_CR_2020_Epigenetic_metabolic_reprogramming_of_right_ventricular_fibroblasts.pdf
fibroblasts in pulmonary arterial hypertension: A pyruvate ... dichloroacetate (DCA), restores mitochondrial glucose metabolism and inhibits cell.
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25
A novel metabolic model for pulmonary hypertension - Frontiers
https://www.frontiersin.org/articles/10.3389/fcvm.2022.957524/full
Pulmonary arterial hypertension, or PAH, is a condition that is characterized by pulmonary artery pressures above 20 mmHg (at rest).
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https://www.frontiersin.org/articles/10.3389/fcvm.2022.957524/full
Pulmonary arterial hypertension, or PAH, is a condition that is characterized by pulmonary artery pressures above 20 mmHg (at rest).
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26
Researchers Find Potential New Treatment for Pulmonary ...
https://rtmagazine.com/disorders-diseases/cardiopulmonary-thoracic/pulmonary-hypertension/researchers-find-potential-new-treatment-for-pulmonary-hypertension/
Pulmonary hypertension is caused by a cancer-like excessive growth of cells in the wall of the lung blood vessels. It causes the lumen, which is the path where ...
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https://rtmagazine.com/disorders-diseases/cardiopulmonary-thoracic/pulmonary-hypertension/researchers-find-potential-new-treatment-for-pulmonary-hypertension/
Pulmonary hypertension is caused by a cancer-like excessive growth of cells in the wall of the lung blood vessels. It causes the lumen, which is the path where ...
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27
A Sham-Controlled Randomized Trial | JACC: Cardiovascular ...
https://www.jacc.org/doi/10.1016/j.jcin.2022.09.013
WHO Group I pulmonary arterial hypertension (PAH) is a progressive, debilitating disease. Previous observational studies have demonstrated ...
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https://www.jacc.org/doi/10.1016/j.jcin.2022.09.013
WHO Group I pulmonary arterial hypertension (PAH) is a progressive, debilitating disease. Previous observational studies have demonstrated ...
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28
Pulmonary artery smooth muscle cells with ... - Research Square
https://www.researchsquare.com/article/rs-1844787/v1.pdf
Pulmonary arterial hypertension (PAH) is life-threatening disease that is ... We then assessed the effects of dichloroacetic acid (DCA), ...
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https://www.researchsquare.com/article/rs-1844787/v1.pdf
Pulmonary arterial hypertension (PAH) is life-threatening disease that is ... We then assessed the effects of dichloroacetic acid (DCA), ...
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29
Inflammatory Basis of Pulmonary Arterial Hypertension
https://pubs.asahq.org/anesthesiology/article/131/4/898/921/Inflammatory-Basis-of-Pulmonary-Arterial
Pulmonary hypertension, defined as a resting mean pulmonary artery pressure greater than or equal to 25 mmHg, results from a myriad of conditions.
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https://pubs.asahq.org/anesthesiology/article/131/4/898/921/Inflammatory-Basis-of-Pulmonary-Arterial
Pulmonary hypertension, defined as a resting mean pulmonary artery pressure greater than or equal to 25 mmHg, results from a myriad of conditions.
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30
Pulmonary Arterial Hypertension: Emerging Principles of ...
https://www.imrpress.com/journal/RCM/23/11/10.31083/j.rcm2311378/htm
Pulmonary hypertension (PH) is a complex and progressive disease involving elevated pressures in the pulmonary arteries due to one or multiple varied etiologies ...
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https://www.imrpress.com/journal/RCM/23/11/10.31083/j.rcm2311378/htm
Pulmonary hypertension (PH) is a complex and progressive disease involving elevated pressures in the pulmonary arteries due to one or multiple varied etiologies ...
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31
Types of Pulmonary Hypertension: The WHO Groups
https://phassociation.org/types-pulmonary-hypertension-groups/
Group 3: Pulmonary Hypertension Due to Lung Disease ... WHO Group 3 includes PH due to chronic lung disease and/or hypoxia (low oxygen levels).
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https://phassociation.org/types-pulmonary-hypertension-groups/
Group 3: Pulmonary Hypertension Due to Lung Disease ... WHO Group 3 includes PH due to chronic lung disease and/or hypoxia (low oxygen levels).
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32
Pathological Mechanisms and Potential Therapeutic Targets ...
http://www.aginganddisease.org/EN/10.14336/AD.2020.0111
Pulmonary arterial hypertension (PAH) is a progressive cardiovascular disease characterized by pulmonary vasculature reconstruction and right ventricular ...
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http://www.aginganddisease.org/EN/10.14336/AD.2020.0111
Pulmonary arterial hypertension (PAH) is a progressive cardiovascular disease characterized by pulmonary vasculature reconstruction and right ventricular ...
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33
Pulmonary Arterial Hypertension (PAH) | Encyclopedia MDPI
https://encyclopedia.pub/entry/19398
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by elevated pulmonary arterial pressure due to increased pulmonary vascular ...
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https://encyclopedia.pub/entry/19398
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by elevated pulmonary arterial pressure due to increased pulmonary vascular ...
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34
key role of apoptosis in the pathogenesis and treatment of ...
https://academic.oup.com/ejcts/article/30/3/499/459126
Pulmonary arterial hypertension can be classified into two categories: (1) primary and (2) secondary. Primary pulmonary hypertension (familial and sporadic) is ...
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https://academic.oup.com/ejcts/article/30/3/499/459126
Pulmonary arterial hypertension can be classified into two categories: (1) primary and (2) secondary. Primary pulmonary hypertension (familial and sporadic) is ...
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35
Efficacy Of DCA Treatment In SM22-5-HTT+ Mice - HAL-Inserm
https://www.hal.inserm.fr/inserm-00499630/en/
Voltage-gated potassium (Kv)1.5 is decreased in pulmonary arteries (PAs) of patients with idiopathic pulmonary arterial hypertension (IPAH) and in ...
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https://www.hal.inserm.fr/inserm-00499630/en/
Voltage-gated potassium (Kv)1.5 is decreased in pulmonary arteries (PAs) of patients with idiopathic pulmonary arterial hypertension (IPAH) and in ...
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36
Updates on the Treatment of Pulmonary Hypertension
https://www.ekjm.org/journal/view.php?number=23825
Pulmonary arterial hypertension (PAH) is a rare and severe clinical condition characterized by luminal obliteration of small pulmonary ...
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https://www.ekjm.org/journal/view.php?number=23825
Pulmonary arterial hypertension (PAH) is a rare and severe clinical condition characterized by luminal obliteration of small pulmonary ...
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37
Dichloroacetic acid Completed Phase 1 Trials for Pulmonary ...
https://go.drugbank.com/drugs/DB08809/clinical_trials?conditions=DBCOND0046708&phase=1&purpose=treatment&status=completed
NCT01083524, Dichloroacetate (DCA) for the Treatment of Pulmonary Arterial Hypertension. Dichloroacetic acid (DB08809) · Sodium dichloroacetate (DB16929) ...
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https://go.drugbank.com/drugs/DB08809/clinical_trials?conditions=DBCOND0046708&phase=1&purpose=treatment&status=completed
NCT01083524, Dichloroacetate (DCA) for the Treatment of Pulmonary Arterial Hypertension. Dichloroacetic acid (DB08809) · Sodium dichloroacetate (DB16929) ...
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38
Epigenetic Metabolic Reprogramming of Right Ventricular ...
https://europepmc.org/article/pmc/7274861
Right ventricular (RV) fibrosis in pulmonary arterial hypertension contributes to ... DCA improves RV function and oxidative glucose metabolism in vivo in ...
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https://europepmc.org/article/pmc/7274861
Right ventricular (RV) fibrosis in pulmonary arterial hypertension contributes to ... DCA improves RV function and oxidative glucose metabolism in vivo in ...
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39
Dichloroacetate treatment partially regresses established ...
https://agris.fao.org/agris-search/search.do?recordID=US201301711079
Dichloroacetate treatment partially regresses established pulmonary hypertension in mice with SM22α-targeted overexpression of the serotonin transporter [2009].
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https://agris.fao.org/agris-search/search.do?recordID=US201301711079
Dichloroacetate treatment partially regresses established pulmonary hypertension in mice with SM22α-targeted overexpression of the serotonin transporter [2009].
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40
Pulmonary Arterial Hypertension | SpringerLink
https://link.springer.com/10.1007/978-3-030-21573-6_10057-1
Pulmonary arterial hypertension (PAH) is a life-threatening lung disease clinically defined by a mean pulmonary artery pressure (mPAP) above 20 mmHg at rest ...
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https://link.springer.com/10.1007/978-3-030-21573-6_10057-1
Pulmonary arterial hypertension (PAH) is a life-threatening lung disease clinically defined by a mean pulmonary artery pressure (mPAP) above 20 mmHg at rest ...
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41
New Generic Drug Helps Treat Pulmonary Hypertension
https://www.medindia.net/news/new-generic-drug-helps-treat-pulmonary-hypertension-174115-1.htm
'Dichloroacetate (DCA) is the new generic drug that targets the mitochondria to decrease blood pressure in the lungs of Pulmonary Arterial ...
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https://www.medindia.net/news/new-generic-drug-helps-treat-pulmonary-hypertension-174115-1.htm
'Dichloroacetate (DCA) is the new generic drug that targets the mitochondria to decrease blood pressure in the lungs of Pulmonary Arterial ...
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42
Targeting mitochondria in pulmonary hypertension - EurekAlert!
https://www.eurekalert.org/news-releases/557785
They showed that the molecular target of DCA (a mitochondrial enzyme called Pyruvate Dehydrogenase Kinase or PDK) was higher in the lungs of PAH ...
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https://www.eurekalert.org/news-releases/557785
They showed that the molecular target of DCA (a mitochondrial enzyme called Pyruvate Dehydrogenase Kinase or PDK) was higher in the lungs of PAH ...
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43
Fasudil Dichloroacetate Alleviates SU5416/Hypoxia-Induced ...
https://search.proquest.com/openview/7939579abf0727be56cc283ad17451f3/1?pq-origsite=gscholar&cbl=2046454
Pulmonary arterial hypertension (PAH), a progressive lung vascular disease with a poor prognosis and limited therapeutic options, is characterized by ...
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https://search.proquest.com/openview/7939579abf0727be56cc283ad17451f3/1?pq-origsite=gscholar&cbl=2046454
Pulmonary arterial hypertension (PAH), a progressive lung vascular disease with a poor prognosis and limited therapeutic options, is characterized by ...
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44
PFKFB3-mediated endothelial glycolysis promotes pulmonary ...
https://www.pnas.org/doi/10.1073/pnas.1821401116
Pulmonary hypertension (PH) is a severe lung disease characterized by the ... others have shown that dichloroacetate (DCA), an inhibitor of pyruvate ...
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https://www.pnas.org/doi/10.1073/pnas.1821401116
Pulmonary hypertension (PH) is a severe lung disease characterized by the ... others have shown that dichloroacetate (DCA), an inhibitor of pyruvate ...
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45
Potential Interventions Against BMPR2-Related Pulmonary ...
https://meridian.allenpress.com/aph/article/11/1/25/432102/Potential-Interventions-Against-BMPR2-Related
Currently there is no therapy known to prevent, delay, or reverse the pulmonary vasculopathy of pulmonary arterial hypertension (PAH). Perhaps ...
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https://meridian.allenpress.com/aph/article/11/1/25/432102/Potential-Interventions-Against-BMPR2-Related
Currently there is no therapy known to prevent, delay, or reverse the pulmonary vasculopathy of pulmonary arterial hypertension (PAH). Perhaps ...
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46
Molecular mechanisms of right ventricular dysfunction in ...
https://cdt.amegroups.com/article/view/44903/html
Abstract: Pulmonary arterial hypertension (PAH) is a rare, life-threatening condition characterized by dysregulated metabolism, pulmonary vascular remodeling, ...
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https://cdt.amegroups.com/article/view/44903/html
Abstract: Pulmonary arterial hypertension (PAH) is a rare, life-threatening condition characterized by dysregulated metabolism, pulmonary vascular remodeling, ...
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47
Molecular Pathways in Pulmonary Arterial Hypertension - MDPI
https://mdpi-res.com/d_attachment/ijms/ijms-23-10001/article_deploy/ijms-23-10001.pdf?version=1662096016
Pulmonary hypertension (PH) is a chronic condition characterized by a progressive ... DCA is a hypothesized treatment option for PAH.
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https://mdpi-res.com/d_attachment/ijms/ijms-23-10001/article_deploy/ijms-23-10001.pdf?version=1662096016
Pulmonary hypertension (PH) is a chronic condition characterized by a progressive ... DCA is a hypothesized treatment option for PAH.
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48
Investigative Therapies in Pulmonary Arterial Hypertension
https://thoracickey.com/investigative-therapies-in-pulmonary-arterial-hypertension/
Pulmonary arterial hypertension (PAH) remains a serious, life threatening disease of unclear etiology. Despite the rapid development of ...
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https://thoracickey.com/investigative-therapies-in-pulmonary-arterial-hypertension/
Pulmonary arterial hypertension (PAH) remains a serious, life threatening disease of unclear etiology. Despite the rapid development of ...
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49
FOXO1-mediated upregulation of pyruvate dehydrogenase ...
https://www.sigmaaldrich.com/AR/en/tech-docs/paper/302715
... dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of ...
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https://www.sigmaaldrich.com/AR/en/tech-docs/paper/302715
... dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of ...
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50
Pulmonary Hypertension Symptoms, Tests & Treatments
https://www.medstarhealth.org/services/pulmonary-hypertension
Pulmonary hypertension occurs when the pulmonary arteries become narrowed. This makes it more difficult for blood to flow through the arteries, leading to ...
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https://www.medstarhealth.org/services/pulmonary-hypertension
Pulmonary hypertension occurs when the pulmonary arteries become narrowed. This makes it more difficult for blood to flow through the arteries, leading to ...
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51
Pulmonary Arterial Hypertension - NORD (National ...
https://rarediseases.org/videos/pulmonary-arterial-hypertension/
Pulmonary arterial hypertension (PAH) is a rare, progressive disorder characterized by high blood pressure (hypertension) in the arteries of the lungs ...
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https://rarediseases.org/videos/pulmonary-arterial-hypertension/
Pulmonary arterial hypertension (PAH) is a rare, progressive disorder characterized by high blood pressure (hypertension) in the arteries of the lungs ...
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52
An Overview of PH and PAH
https://www.ajmc.com/view/an-overview-of-ph-and-pah
Pulmonary arterial hypertension [PAH] is a subgroup of pulmonary hypertension that's characterized by an elevated mean pulmonary artery pressure ...
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https://www.ajmc.com/view/an-overview-of-ph-and-pah
Pulmonary arterial hypertension [PAH] is a subgroup of pulmonary hypertension that's characterized by an elevated mean pulmonary artery pressure ...
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53
Effects of DHEA in Pulmonary Hypertension (DiPH) - Grantome
https://grantome.com/grant/NIH/R01-HL141268-03
Pulmonary arterial hypertension (PAH) is a pulmonary vasculopathy that remains progressive and life-limiting despite numerous approved vasodilator therapies ...
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https://grantome.com/grant/NIH/R01-HL141268-03
Pulmonary arterial hypertension (PAH) is a pulmonary vasculopathy that remains progressive and life-limiting despite numerous approved vasodilator therapies ...
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54
Targeting Molecular Pathway that Causes Pulmonary Arterial ...
https://health.ucsd.edu/news/releases/Pages/2022-05-06-targeting-molecular-pathway-that-causes-pulmonary-arterial-hypertension.aspx
Pulmonary arterial hypertension (PAH) is a type of high blood pressure in the lungs, in which blood vessels are narrowed, ...
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https://health.ucsd.edu/news/releases/Pages/2022-05-06-targeting-molecular-pathway-that-causes-pulmonary-arterial-hypertension.aspx
Pulmonary arterial hypertension (PAH) is a type of high blood pressure in the lungs, in which blood vessels are narrowed, ...
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55
Pulmonary Arterial Hypertension (PAH) - DynaMed
https://www.dynamed.com/condition/pulmonary-arterial-hypertension-pah
Class I - patients with pulmonary hypertension but without resulting limitation of physical activity; ordinary physical activity does not cause undue dyspnea or ...
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https://www.dynamed.com/condition/pulmonary-arterial-hypertension-pah
Class I - patients with pulmonary hypertension but without resulting limitation of physical activity; ordinary physical activity does not cause undue dyspnea or ...
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56
Pulmonary Arterial Hypertension (PAH) - The Lung Docs
https://www.thelungdocs.com/services/pulmonary-hypertension/
PAH is one type of pulmonary hypertension, which refers to high blood pressure in the lungs. Pulmonary arterial hypertension happens when small arteries in the ...
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https://www.thelungdocs.com/services/pulmonary-hypertension/
PAH is one type of pulmonary hypertension, which refers to high blood pressure in the lungs. Pulmonary arterial hypertension happens when small arteries in the ...
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57
Pulmonary Hypertension Demystified - YouTube
https://www.youtube.com/watch?v=WvFjLb-voWk
Icahn School of Medicine
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https://www.youtube.com/watch?v=WvFjLb-voWk
Icahn School of Medicine
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58
Pulmonary Hypertension: The Present and Future
https://books.google.com/books?id=YBwco7qgj-4C&pg=PA41&lpg=PA41&dq=dca+pulmonary+hypertension&source=bl&ots=89dfdA3L6n&sig=ACfU3U09jP-8JOiP8AIDzPIUQ_VxmT0Lgg&hl=en&sa=X&ved=2ahUKEwiS3rD339X7AhXxFFkFHdlhBW8Q6AF6BQjiARAD
Dichloroacetate reverses pulmonary arterial hypertension ( PAH ) . ( A ) , ( B ) Dichloroacetate ( DCA ) reverses elevated pulmonary artery pressure and ...
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https://books.google.com/books?id=YBwco7qgj-4C&pg=PA41&lpg=PA41&dq=dca+pulmonary+hypertension&source=bl&ots=89dfdA3L6n&sig=ACfU3U09jP-8JOiP8AIDzPIUQ_VxmT0Lgg&hl=en&sa=X&ved=2ahUKEwiS3rD339X7AhXxFFkFHdlhBW8Q6AF6BQjiARAD
Dichloroacetate reverses pulmonary arterial hypertension ( PAH ) . ( A ) , ( B ) Dichloroacetate ( DCA ) reverses elevated pulmonary artery pressure and ...
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59
Pulmonary Hypertension - Page 41 - Google Books Result
https://books.google.com/books?id=OlQrAwAAQBAJ&pg=PA41&lpg=PA41&dq=dca+pulmonary+hypertension&source=bl&ots=2ikdOabbps&sig=ACfU3U1zF8naCyc-KOhfGftDA7OUuxij0Q&hl=en&sa=X&ved=2ahUKEwiS3rD339X7AhXxFFkFHdlhBW8Q6AF6BQjhARAD
Dichloroacetate reverses pulmonary arterial hypertension (PAH). (A), (B) Dichloroacetate (DCA) reverses elevated pulmonary artery pressure and pulmonary ...
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https://books.google.com/books?id=OlQrAwAAQBAJ&pg=PA41&lpg=PA41&dq=dca+pulmonary+hypertension&source=bl&ots=2ikdOabbps&sig=ACfU3U1zF8naCyc-KOhfGftDA7OUuxij0Q&hl=en&sa=X&ved=2ahUKEwiS3rD339X7AhXxFFkFHdlhBW8Q6AF6BQjhARAD
Dichloroacetate reverses pulmonary arterial hypertension (PAH). (A), (B) Dichloroacetate (DCA) reverses elevated pulmonary artery pressure and pulmonary ...
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60
Pulmonary Hypertension: Basic Science to Clinical Medicine
https://books.google.com/books?id=D73fCgAAQBAJ&pg=PA141&lpg=PA141&dq=dca+pulmonary+hypertension&source=bl&ots=QU_FBSYIkv&sig=ACfU3U3fVP1wrYjrUXZFf8EFRTUjwguFiQ&hl=en&sa=X&ved=2ahUKEwiS3rD339X7AhXxFFkFHdlhBW8Q6AF6BQjZARAD
Much work remains to determine which types of pulmonary hypertension are driven or ... Dichloroacetate (DCA), a pharmacologic inhibitor of PDK used for many ...
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https://books.google.com/books?id=D73fCgAAQBAJ&pg=PA141&lpg=PA141&dq=dca+pulmonary+hypertension&source=bl&ots=QU_FBSYIkv&sig=ACfU3U3fVP1wrYjrUXZFf8EFRTUjwguFiQ&hl=en&sa=X&ved=2ahUKEwiS3rD339X7AhXxFFkFHdlhBW8Q6AF6BQjZARAD
Much work remains to determine which types of pulmonary hypertension are driven or ... Dichloroacetate (DCA), a pharmacologic inhibitor of PDK used for many ...
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