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Google Keyword Rankings for : o dealkylation wiki
1
Dealkylation - Wikipedia
https://en.wikipedia.org/?title=Dealkylation&redirect=no
Hydrodealkylation is a chemical reaction that often involves reacting an aromatic hydrocarbon, such as toluene, in the presence of hydrogen gas to form a ...
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https://en.wikipedia.org/?title=Dealkylation&redirect=no
Hydrodealkylation is a chemical reaction that often involves reacting an aromatic hydrocarbon, such as toluene, in the presence of hydrogen gas to form a ...
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2
dealkylation - Wiktionary
https://en.wiktionary.org/wiki/dealkylation
dealkylation (plural dealkylations). (organic chemistry) The removal of alkyl groups from a compound. Related termsEdit.
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https://en.wiktionary.org/wiki/dealkylation
dealkylation (plural dealkylations). (organic chemistry) The removal of alkyl groups from a compound. Related termsEdit.
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3
Dealkylation - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/dealkylation
A single drug may be transformed into several metabolites, depending on the relative rates of various enzyme reactions, the drug concentration in different ...
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https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/dealkylation
A single drug may be transformed into several metabolites, depending on the relative rates of various enzyme reactions, the drug concentration in different ...
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4
Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in ...
https://m.wikidata.org/wiki/Q72207242
Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver ... Statements. instance of ... Wikipedia(0 entries).
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https://m.wikidata.org/wiki/Q72207242
Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver ... Statements. instance of ... Wikipedia(0 entries).
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5
Ester Cleavages via SN2-Type Dealkylation
http://organicreactions.org/index.php?title=Ester_Cleavages_via_SN2-Type_Dealkylation&mobileaction=toggle_view_desktop
Ester Cleavages via SN2-Type Dealkylation. Brought to you by the Organic Reactions Wiki, the online collection of organic reactions.
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http://organicreactions.org/index.php?title=Ester_Cleavages_via_SN2-Type_Dealkylation&mobileaction=toggle_view_desktop
Ester Cleavages via SN2-Type Dealkylation. Brought to you by the Organic Reactions Wiki, the online collection of organic reactions.
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6
File:Oxidation reactions by cytochrome P-450 ... - Wikibooks
https://en.wikibooks.org/wiki/File:Oxidation_reactions_by_cytochrome_P-450_mixed_function_oxidases.png
The Wikibooks community has accepted video game strategy guides on this wiki! ... Middle: O-dealkylation, where oxygen is added across an O-C bond creating ...
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https://en.wikibooks.org/wiki/File:Oxidation_reactions_by_cytochrome_P-450_mixed_function_oxidases.png
The Wikibooks community has accepted video game strategy guides on this wiki! ... Middle: O-dealkylation, where oxygen is added across an O-C bond creating ...
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7
Cyp3a11 - cytochrome P450, family 3, subfamily a - WikiGenes
https://www.wikigenes.org/e/gene/e/13112.html
The reduction of murine hepatic Cyp3a gene expression in tumor-bearing mice ... hepatic microsomal activities for pentoxyresorufin O-dealkylation (PROD) and ...
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https://www.wikigenes.org/e/gene/e/13112.html
The reduction of murine hepatic Cyp3a gene expression in tumor-bearing mice ... hepatic microsomal activities for pentoxyresorufin O-dealkylation (PROD) and ...
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8
Defective Cytochrome P450-Catalysed Drug Metabolism in ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152007
The reduced activity of P450 enzymes may be the result of bile acid ... P450 enzymatic O-dealkylation activity assayed in Npc1+/+, Npc1+/-, ...
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152007
The reduced activity of P450 enzymes may be the result of bile acid ... P450 enzymatic O-dealkylation activity assayed in Npc1+/+, Npc1+/-, ...
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9
Induction, CYP1A2/CYP1A5 - AOP-Wiki
https://aopwiki.org/events/850
↑ Burke, M. D., Thompson, S., Weaver, R. J., Wolf, C. R., and Mayer, R. T. (1994). Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and ...
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https://aopwiki.org/events/850
↑ Burke, M. D., Thompson, S., Weaver, R. J., Wolf, C. R., and Mayer, R. T. (1994). Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and ...
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10
N-Dealkylation of an N-Cyclopropylamine by Horseradish ...
https://pubs.acs.org/doi/10.1021/ja0111479
Cyclopropylamines inactivate cytochrome P450 enzymes which catalyze their oxidative N-dealkylation. A key intermediate in both processes is ...
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https://pubs.acs.org/doi/10.1021/ja0111479
Cyclopropylamines inactivate cytochrome P450 enzymes which catalyze their oxidative N-dealkylation. A key intermediate in both processes is ...
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11
Inhibition of Cytochrome P450 1A2-Mediated Metabolism and ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252637/
The publisher's final edited version of this article is available at Drug ... The rate of O-dealkylation of 7ERF by rat liver microsomes was determined as ...
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252637/
The publisher's final edited version of this article is available at Drug ... The rate of O-dealkylation of 7ERF by rat liver microsomes was determined as ...
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12
Codeine and morphine metabolism (Homo sapiens)
https://www.wikipathways.org/index.php/Pathway:WP1604
The principal pathways for the metabolism of codeine occur in the liver, ... CYP2D6, GeneProduct, 1565 (Entrez Gene), O-dealkylation.
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https://www.wikipathways.org/index.php/Pathway:WP1604
The principal pathways for the metabolism of codeine occur in the liver, ... CYP2D6, GeneProduct, 1565 (Entrez Gene), O-dealkylation.
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13
CYP2D6 - wikidoc
https://www.wikidoc.org/index.php/CYP2D6
So, the dose of the drug may have to be adjusted to take into account of the speed at which it is metabolized by CYP2D6. Other drugs may ...
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https://www.wikidoc.org/index.php/CYP2D6
So, the dose of the drug may have to be adjusted to take into account of the speed at which it is metabolized by CYP2D6. Other drugs may ...
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14
lessons-learnt-presence-n-nitrosamine-impurities-sartan ...
https://www.ema.europa.eu/en/documents/report/lessons-learnt-presence-n-nitrosamine-impurities-sartan-medicines_en.pdf
dealkylative processes56. A range of alternative synthetic procedures for N-nitrosamines have been documented. These include.
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https://www.ema.europa.eu/en/documents/report/lessons-learnt-presence-n-nitrosamine-impurities-sartan-medicines_en.pdf
dealkylative processes56. A range of alternative synthetic procedures for N-nitrosamines have been documented. These include.
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15
2x8b - Proteopedia, life in 3D
https://proteopedia.org/wiki/index.php/2x8b
We solved the X-ray structure of aged tabun-hAChE complexed with fasciculin II, and we show that aging proceeds through O-dealkylation, in agreement with ...
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https://proteopedia.org/wiki/index.php/2x8b
We solved the X-ray structure of aged tabun-hAChE complexed with fasciculin II, and we show that aging proceeds through O-dealkylation, in agreement with ...
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16
Oxybenzone - Wikipedia
https://www.secondchoice.life/?_=%2Fwiki%2FOxybenzone%23Mf97lN4jZWkzWcMcaqhFmPDw8bCzKm0Hsg%3D%3D
To form DHB the methoxy functional group undergoes O-dealkylation; to form THB the same ring is hydroxylated. Ring B in oxybenzone is hydroxylated to form ...
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https://www.secondchoice.life/?_=%2Fwiki%2FOxybenzone%23Mf97lN4jZWkzWcMcaqhFmPDw8bCzKm0Hsg%3D%3D
To form DHB the methoxy functional group undergoes O-dealkylation; to form THB the same ring is hydroxylated. Ring B in oxybenzone is hydroxylated to form ...
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17
Metabolic Pathways and Potencies of New Fentanyl Analogs
https://www.frontiersin.org/articles/10.3389/fphar.2019.00238/full
In humans, fentanyl is mainly metabolized in the liver by CYP3A4 into norfentanyl through oxidative N-dealkylation at the piperidine ring by ...
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https://www.frontiersin.org/articles/10.3389/fphar.2019.00238/full
In humans, fentanyl is mainly metabolized in the liver by CYP3A4 into norfentanyl through oxidative N-dealkylation at the piperidine ring by ...
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18
Voriconazole: Uses, Interactions, Mechanism of ... - DrugBank
https://go.drugbank.com/drugs/DB00582
For the treatment of esophageal candidiasis, cadidemia, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and ...
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https://go.drugbank.com/drugs/DB00582
For the treatment of esophageal candidiasis, cadidemia, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and ...
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19
Category:GO:0006307 ! DNA dealkylation involved in DNA ...
https://gowiki.tamu.edu/wiki/index.php/Category:GO:0006307_!_DNA_dealkylation_involved_in_DNA_repair
def: "The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA ...
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https://gowiki.tamu.edu/wiki/index.php/Category:GO:0006307_!_DNA_dealkylation_involved_in_DNA_repair
def: "The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA ...
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20
Nitrosamines as Impurities in Drugs; Health Risk ... - FDA
https://www.fda.gov/media/147331/download
The carcinogenic effect of nitrosodimethylamine in Rats. Naturwissen. 46: 175 ... O. OCH2R1. +. DNA alkylation ... Synthesis (Wikipedia).
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https://www.fda.gov/media/147331/download
The carcinogenic effect of nitrosodimethylamine in Rats. Naturwissen. 46: 175 ... O. OCH2R1. +. DNA alkylation ... Synthesis (Wikipedia).
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21
Pharmacology of Antidepressant Medications
https://www.pharmacology2000.com/Central/Antidepressant2/Depression-25.htm
The primary pathway for metabolism is mediated by CYP2D6 via N-methylation to norfluoxetine with a minor pathway involving O-dealkylation to an inactive ...
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https://www.pharmacology2000.com/Central/Antidepressant2/Depression-25.htm
The primary pathway for metabolism is mediated by CYP2D6 via N-methylation to norfluoxetine with a minor pathway involving O-dealkylation to an inactive ...
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22
File:Oxidation reactions by cytochrome ... - Wikimedia Commons
https://commons.wikimedia.org/wiki/File:Oxidation_reactions_by_cytochrome_P-450_mixed_function_oxidases.png
Middle: O-dealkylation, where oxygen is added across an O-C bond creating two alcohols. ... The following other wikis use this file:.
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https://commons.wikimedia.org/wiki/File:Oxidation_reactions_by_cytochrome_P-450_mixed_function_oxidases.png
Middle: O-dealkylation, where oxygen is added across an O-C bond creating two alcohols. ... The following other wikis use this file:.
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23
UBTD1 and KIAA2026 Interaction - Wiki-Pi
https://hagrid.dbmi.pitt.edu/wiki-pi/index.php/pair/view/80019/158358
Wiki-Pi: a web resource for human protein-protein interactions. ... Positive Regulation Of Stem Cell Maintenance · DNA Dealkylation Involved In DNA Repair ...
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https://hagrid.dbmi.pitt.edu/wiki-pi/index.php/pair/view/80019/158358
Wiki-Pi: a web resource for human protein-protein interactions. ... Positive Regulation Of Stem Cell Maintenance · DNA Dealkylation Involved In DNA Repair ...
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24
definition of Dealkylation by The Free Dictionary
https://www.thefreedictionary.com/Dealkylation
To add one or more alkyl groups to (a compound). al′kyl·a′tion (-kə-lā′shən) n. American Heritage® Dictionary ...
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https://www.thefreedictionary.com/Dealkylation
To add one or more alkyl groups to (a compound). al′kyl·a′tion (-kə-lā′shən) n. American Heritage® Dictionary ...
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25
Cytochrome P450 CYP1A1: wider roles in cancer progression ...
https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-9-187
CYP1A1 is one of the main cytochrome P450 enzymes, examined extensively for its ... such as C-, N- and S- oxidation and dealkylation.
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https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-9-187
CYP1A1 is one of the main cytochrome P450 enzymes, examined extensively for its ... such as C-, N- and S- oxidation and dealkylation.
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26
Structure and mechanism of the complex between cytochrome ...
https://www.pnas.org/doi/10.1073/pnas.1010693107
Ritonavir is a HIV protease inhibitor routinely prescribed to HIV patients that also potently inactivates cytochrome P4503A4 (CYP3A4), ...
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https://www.pnas.org/doi/10.1073/pnas.1010693107
Ritonavir is a HIV protease inhibitor routinely prescribed to HIV patients that also potently inactivates cytochrome P4503A4 (CYP3A4), ...
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27
The Role Of The Liver In Drug Metabolism : WFSA - Resources
https://resources.wfsahq.org/atotw/the-role-of-the-liver-in-drug-metabolism/
Phase 1 oxidative reactions catalysed by cytochrome P450 include hydroxylation, epoxidation, dealkylation, deamination and dehalogenation ...
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https://resources.wfsahq.org/atotw/the-role-of-the-liver-in-drug-metabolism/
Phase 1 oxidative reactions catalysed by cytochrome P450 include hydroxylation, epoxidation, dealkylation, deamination and dehalogenation ...
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28
Assay for quantitative determination of CYP1A1 enzyme ...
https://protocols.scienceexchange.com/protocols/assay-for-quantitative-determination-of-cyp1a1-enzyme-activity-using-7-ethoxyresorufin-as-standard-substrate-erod-assay-09844e57-aa7a-4eaf-af7a-a6caa93d42cb
Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver. Biochem Pharmacol 1994;48:923-36. Sousa RL, Marletta MA.
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https://protocols.scienceexchange.com/protocols/assay-for-quantitative-determination-of-cyp1a1-enzyme-activity-using-7-ethoxyresorufin-as-standard-substrate-erod-assay-09844e57-aa7a-4eaf-af7a-a6caa93d42cb
Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver. Biochem Pharmacol 1994;48:923-36. Sousa RL, Marletta MA.
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29
QSAR Toolbox - OECD
https://www.oecd.org/chemicalsafety/risk-assessment/TB4_Application_manual_F1.compressed.pdf
one of the available names (2) within eChemPortal, PubChem, Wikipedia or ... oxidative N- and O-dealkylation, epoxidation, ester and amide hydrolysis,.
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https://www.oecd.org/chemicalsafety/risk-assessment/TB4_Application_manual_F1.compressed.pdf
one of the available names (2) within eChemPortal, PubChem, Wikipedia or ... oxidative N- and O-dealkylation, epoxidation, ester and amide hydrolysis,.
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30
Article Figures & Data - Drug Metabolism & Disposition
https://dmd.aspetjournals.org/content/32/10/1111/tab-figures-data
QUANTITATIVE STRUCTURE-METABOLISM RELATIONSHIP MODELING OF METABOLIC N-DEALKYLATION REACTION RATES. Konstantin V. Balakin, Sean Ekins, ...
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https://dmd.aspetjournals.org/content/32/10/1111/tab-figures-data
QUANTITATIVE STRUCTURE-METABOLISM RELATIONSHIP MODELING OF METABOLIC N-DEALKYLATION REACTION RATES. Konstantin V. Balakin, Sean Ekins, ...
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31
Role of DMPK Platform T h l & K l d Technology & Knowledge ...
https://www.rsc.org/images/andy_harrell_tcm18-239218.pdf
Definition of a Platform Science and Knowledge ... Metasite predicted O-dealkylation as most likely ... Platform: DMPK WIKI, In vitro assays.
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https://www.rsc.org/images/andy_harrell_tcm18-239218.pdf
Definition of a Platform Science and Knowledge ... Metasite predicted O-dealkylation as most likely ... Platform: DMPK WIKI, In vitro assays.
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32
Metoprolol Tartrate 50 mg tablets - (emc)
https://www.medicines.org.uk/emc/product/5345/smpc
Metoprolol Tartrate 50 mg tablets - Summary of Product Characteristics (SmPC) by ... It is extensively metabolised in the liver; O-dealkylation followed by ...
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https://www.medicines.org.uk/emc/product/5345/smpc
Metoprolol Tartrate 50 mg tablets - Summary of Product Characteristics (SmPC) by ... It is extensively metabolised in the liver; O-dealkylation followed by ...
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33
Drug Metabolism - DolceraWiki
http://dolcera.com/wiki/index.php/Drug_Metabolism
1 Introduction; 2 Metabolism Sites; 3 Fate of Metabolized drugs ... Dealkylation: minus the alkyl group: minus 14 u for a methyl group, ...
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http://dolcera.com/wiki/index.php/Drug_Metabolism
1 Introduction; 2 Metabolism Sites; 3 Fate of Metabolized drugs ... Dealkylation: minus the alkyl group: minus 14 u for a methyl group, ...
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34
a textbook of modern toxicology - HNS Spills E-Learning
http://wikimariner.actionmodulers.com/wiki/images/8/80/Modern_Toxicology_4ed.pdf
The definition of a poison, or toxicant, also involves a qualitative ... The O - dealkylation of organophosphorus triesters differs from that of p-.
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http://wikimariner.actionmodulers.com/wiki/images/8/80/Modern_Toxicology_4ed.pdf
The definition of a poison, or toxicant, also involves a qualitative ... The O - dealkylation of organophosphorus triesters differs from that of p-.
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35
CATOFIN®
https://www.clariant.com/en/Solutions/Products/2014/06/16/09/01/Catofin
CATOFIN®. High-Performance Catalyst for Selective Dehydrogenation & Dealkylation of Hydrocarbons to Produce On-Purpose Propylene.
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https://www.clariant.com/en/Solutions/Products/2014/06/16/09/01/Catofin
CATOFIN®. High-Performance Catalyst for Selective Dehydrogenation & Dealkylation of Hydrocarbons to Produce On-Purpose Propylene.
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36
O-dealkylation, S-dealkylation, Oxidation of Double bonds
https://quizlet.com/271316925/o-dealkylation-s-dealkylation-oxidation-of-double-bonds-flash-cards/
Study with Quizlet and memorize flashcards containing terms like O-dealkylation is a common, Metabolism of codeine, If person is a slow metabolizer of ...
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https://quizlet.com/271316925/o-dealkylation-s-dealkylation-oxidation-of-double-bonds-flash-cards/
Study with Quizlet and memorize flashcards containing terms like O-dealkylation is a common, Metabolism of codeine, If person is a slow metabolizer of ...
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37
Specific solvent issues with amide reduction
https://reagents.acsgcipr.org/reagent-guides/amide-reduction/list-of-reagents/specific-solvent-issues-with-amide-reduction
Historically, LiAlH4 has often been used in diethyl ether due to its unusually high solubility in ... http://en.wikipedia.org/wiki/Lithium_aluminium_hydride.
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https://reagents.acsgcipr.org/reagent-guides/amide-reduction/list-of-reagents/specific-solvent-issues-with-amide-reduction
Historically, LiAlH4 has often been used in diethyl ether due to its unusually high solubility in ... http://en.wikipedia.org/wiki/Lithium_aluminium_hydride.
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38
dealkylation — Translation in Danish - TechDico
https://www.techdico.com/translation/english-danish/dealkylation.html
Many translation examples sorted by field of work of “dealkylation” – English-Danish dictionary and smart ... general - CCMatrix (Wikipedia + CommonCrawl).
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https://www.techdico.com/translation/english-danish/dealkylation.html
Many translation examples sorted by field of work of “dealkylation” – English-Danish dictionary and smart ... general - CCMatrix (Wikipedia + CommonCrawl).
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39
Property:Has abstract - Bioblast
https://wiki.oroboros.at/index.php?title=Property:Has_abstract&limit=20&offset=1660&from=&until=&filter=
Here we investigate the role of Lsd1 in brown adipose tissue (BAT) and find that ... The O-dealkylation of 7-alkoxyresorufins to the highly fluorescent ...
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https://wiki.oroboros.at/index.php?title=Property:Has_abstract&limit=20&offset=1660&from=&until=&filter=
Here we investigate the role of Lsd1 in brown adipose tissue (BAT) and find that ... The O-dealkylation of 7-alkoxyresorufins to the highly fluorescent ...
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40
P.P.TEMPLATE KOREA - UNECE Wiki
https://wiki.unece.org/download/attachments/27459612/VIAQ-02-08%20-%20%28Korea%29Substances%20to%20be%20measured.pptx?api=v2
Ministry of Land, Infrastructure and Transport ... of polymers; chemical intermediate (benzene dealkylation); component of car exhaust and tobacco smoke.
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https://wiki.unece.org/download/attachments/27459612/VIAQ-02-08%20-%20%28Korea%29Substances%20to%20be%20measured.pptx?api=v2
Ministry of Land, Infrastructure and Transport ... of polymers; chemical intermediate (benzene dealkylation); component of car exhaust and tobacco smoke.
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41
Dirlotapide - ToxBank Gold Compounds and Biological ...
https://wiki.toxbank.net/wiki/Dirlotapide
In humans, dirlotapide gives rise to metabolites, specifically the products of mono and bis N- dealkylation at the terminal amide nitrogen.
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https://wiki.toxbank.net/wiki/Dirlotapide
In humans, dirlotapide gives rise to metabolites, specifically the products of mono and bis N- dealkylation at the terminal amide nitrogen.
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42
Fentanyls continue to replace heroin in the drug arena
https://link.springer.com/article/10.1007/s11419-017-0379-4
Ocfentanil and carfentanil are two potent synthetic opioids that are analogues of fentanyl and are actively involved in the recent fentanyl ...
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https://link.springer.com/article/10.1007/s11419-017-0379-4
Ocfentanil and carfentanil are two potent synthetic opioids that are analogues of fentanyl and are actively involved in the recent fentanyl ...
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43
Edarbyclor (Azilsartan Medoxomil and Chlorthalidone Tablets)
https://www.rxlist.com/edarbyclor-drug.htm
Edarbyclor is a combination of azilsartan medoxomil (ARB; as its potassium ... The major metabolite in plasma is formed by O-dealkylation, referred to as ...
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https://www.rxlist.com/edarbyclor-drug.htm
Edarbyclor is a combination of azilsartan medoxomil (ARB; as its potassium ... The major metabolite in plasma is formed by O-dealkylation, referred to as ...
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44
Compound Discoverer Software | Thermo Fisher Scientific - US
https://www.thermofisher.com/us/en/home/industrial/mass-spectrometry/liquid-chromatography-mass-spectrometry-lc-ms/lc-ms-software/multi-omics-data-analysis/compound-discoverer-software.html
Solve ms data analysis challenges like small molecule identification and characterization with a comprehensive, integrated set of libraries, databases and ...
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https://www.thermofisher.com/us/en/home/industrial/mass-spectrometry/liquid-chromatography-mass-spectrometry-lc-ms/lc-ms-software/multi-omics-data-analysis/compound-discoverer-software.html
Solve ms data analysis challenges like small molecule identification and characterization with a comprehensive, integrated set of libraries, databases and ...
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45
cmoJ - SubtiWiki
http://subtiwiki.uni-goettingen.de/wiki//index.php/CmoJ
flavin-dependent monooxygenase, required for the conversion of ... Danchin A, Begley TPCysteine Dealkylation in Bacillus subtilis by a Novel ...
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http://subtiwiki.uni-goettingen.de/wiki//index.php/CmoJ
flavin-dependent monooxygenase, required for the conversion of ... Danchin A, Begley TPCysteine Dealkylation in Bacillus subtilis by a Novel ...
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46
William Mitch - Stanford Profiles
https://profiles.stanford.edu/william-mitch
Returning to UC Berkeley in 2000, he received his PhD in Civil and Environmental Engineering in 2003. He moved to Yale as an assistant professor after ...
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https://profiles.stanford.edu/william-mitch
Returning to UC Berkeley in 2000, he received his PhD in Civil and Environmental Engineering in 2003. He moved to Yale as an assistant professor after ...
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47
Friedel-Crafts Alkylation - Organic Chemistry Portal
https://www.organic-chemistry.org/namedreactions/friedel-crafts-alkylation.shtm
This Lewis acid-catalyzed electrophilic aromatic substitution allows the synthesis of alkylated products via the reaction of arenes with alkyl halides or ...
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https://www.organic-chemistry.org/namedreactions/friedel-crafts-alkylation.shtm
This Lewis acid-catalyzed electrophilic aromatic substitution allows the synthesis of alkylated products via the reaction of arenes with alkyl halides or ...
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48
Human Gene CYP2E1 (ENST00000252945.8) from ...
http://genome.cse.ucsc.edu/cgi-bin/hgGene?org=Human&hgg_chrom=none&hgg_type=knownGene&hgg_gene=uc001lnj.1
RefSeq Summary (NM_000773): This gene encodes a member of the cytochrome P450 superfamily ... Note=CYP2E1 entry; URL="http://en.wikipedia.org/wiki/CYP2E1";
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http://genome.cse.ucsc.edu/cgi-bin/hgGene?org=Human&hgg_chrom=none&hgg_type=knownGene&hgg_gene=uc001lnj.1
RefSeq Summary (NM_000773): This gene encodes a member of the cytochrome P450 superfamily ... Note=CYP2E1 entry; URL="http://en.wikipedia.org/wiki/CYP2E1";
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49
Principles of Absorption, Distribution, Metabolism, and Excretion
https://journals.sagepub.com/doi/pdf/10.1177/019262339502300202
A knowledge of the fate of a drug, its disposition (absorption, distribution, metabolism, ... droxylation (metoprolol), and l~-dealkylation (ami-.
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https://journals.sagepub.com/doi/pdf/10.1177/019262339502300202
A knowledge of the fate of a drug, its disposition (absorption, distribution, metabolism, ... droxylation (metoprolol), and l~-dealkylation (ami-.
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50
N-Ethylhexedrone - PsychonautWiki
https://psychonautwiki.org/wiki/N-Ethylhexedrone
N-Ethylhexedrone is a derivative of hexedrone and is part of a diverse ... compound is likely metabolized through N-dealkylation and/or reduction of the ...
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https://psychonautwiki.org/wiki/N-Ethylhexedrone
N-Ethylhexedrone is a derivative of hexedrone and is part of a diverse ... compound is likely metabolized through N-dealkylation and/or reduction of the ...
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51
Biotransformation - WikiLectures
https://www.wikilectures.eu/w/Biotransformation
10 Oxidation of unsaturated bonds; 11 O-Dealkylation; 12 N-Dealkylation; 13 N-Oxidation; 14 S-Oxidation; 15 Oxidative desulfurization ...
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https://www.wikilectures.eu/w/Biotransformation
10 Oxidation of unsaturated bonds; 11 O-Dealkylation; 12 N-Dealkylation; 13 N-Oxidation; 14 S-Oxidation; 15 Oxidative desulfurization ...
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52
Metabolic N-Dealkylation and N-Oxidation | Encyclopedia MDPI
https://encyclopedia.pub/9572
Metabolic reactions that occur at alkylamino moieties may provide insight into the roles of these moieties when they are parts of drug molecules that act at ...
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https://encyclopedia.pub/9572
Metabolic reactions that occur at alkylamino moieties may provide insight into the roles of these moieties when they are parts of drug molecules that act at ...
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53
Refractory metals | Cerámica Wiki | Fandom
https://ceramica.fandom.com/wiki/Refractory_metals
It is used as a catalyst in reactions such as alkylation, dealkylation, hydrogenation and oxidation. However its rarity makes it the most expensive of the ...
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https://ceramica.fandom.com/wiki/Refractory_metals
It is used as a catalyst in reactions such as alkylation, dealkylation, hydrogenation and oxidation. However its rarity makes it the most expensive of the ...
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54
Idarubicin hydrochloride 57852-57-0 wiki
https://www.guidechem.com/encyclopedia/idarubicin-hydrochloride-dic25176.html
Idarubicin hydrochloride is a derivative of daunorubicin indicated for acute nonlymphocyticleukemia, acute lymphocytic leukemia, and acute myeloid leukemia.
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https://www.guidechem.com/encyclopedia/idarubicin-hydrochloride-dic25176.html
Idarubicin hydrochloride is a derivative of daunorubicin indicated for acute nonlymphocyticleukemia, acute lymphocytic leukemia, and acute myeloid leukemia.
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55
Axens: Homepage
https://www.axens.net/
Axens provides solutions for the conversion of oil and biomass to cleaner fuels, production & purification of major petrochemical intermediates and gas.
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https://www.axens.net/
Axens provides solutions for the conversion of oil and biomass to cleaner fuels, production & purification of major petrochemical intermediates and gas.
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56
CYP3A4 - Wikipedia
https://www.ca.crh.com/host-https-en.m.wikipedia.org/wiki/CYP3A4
These include hydroxylation, epoxidation of olefins, aromatic oxidation, heteroatom oxidations, N- and O- dealkylation reactions, aldehyde oxidations, ...
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https://www.ca.crh.com/host-https-en.m.wikipedia.org/wiki/CYP3A4
These include hydroxylation, epoxidation of olefins, aromatic oxidation, heteroatom oxidations, N- and O- dealkylation reactions, aldehyde oxidations, ...
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57
Oxidative degradations. (a) Exemplary O-dealkylation shown ...
https://www.researchgate.net/figure/Oxidative-degradations-a-Exemplary-O-dealkylation-shown-for-the-metabolic-degradation_fig1_265789166
(a) Exemplary O-dealkylation shown for the metabolic degradation of phenacetin by CYP1A2. The oxygen activated by the enzyme attacks next to the ether and forms ...
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https://www.researchgate.net/figure/Oxidative-degradations-a-Exemplary-O-dealkylation-shown-for-the-metabolic-degradation_fig1_265789166
(a) Exemplary O-dealkylation shown for the metabolic degradation of phenacetin by CYP1A2. The oxygen activated by the enzyme attacks next to the ether and forms ...
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58
GO:0035510 DNA dealkylation - Human Salivary Proteome Wiki
https://www.salivaryproteome.org/public/index.php/Special:Ontology_Term/GO:0035510
... Accession: GO:0035510; Term Name: DNA dealkylation; Created By: bf; Creation Date: 2010-04-30T02:20:08Z; Definition: The removal of an alkyl group from ...
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https://www.salivaryproteome.org/public/index.php/Special:Ontology_Term/GO:0035510
... Accession: GO:0035510; Term Name: DNA dealkylation; Created By: bf; Creation Date: 2010-04-30T02:20:08Z; Definition: The removal of an alkyl group from ...
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59
Ximelagatran - Wikipedia
https://201708014.azurewebsites.net/index.php?q=oKipp7eAc2SWr3HmtNTZ4JzJqsRgwuHce-fP2bV-udajpL-7qtvM3Q
In 2006, its manufacturer AstraZeneca announced that it would withdraw pending applications for marketing approval after reports of hepatotoxicity (liver ...
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https://201708014.azurewebsites.net/index.php?q=oKipp7eAc2SWr3HmtNTZ4JzJqsRgwuHce-fP2bV-udajpL-7qtvM3Q
In 2006, its manufacturer AstraZeneca announced that it would withdraw pending applications for marketing approval after reports of hepatotoxicity (liver ...
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60
Cytochrome P450 - YouTube
https://www.youtube.com/watch?v=rUSOtkvZx_k
University of Rochester Biochemistry (Bio250)
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https://www.youtube.com/watch?v=rUSOtkvZx_k
University of Rochester Biochemistry (Bio250)
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61
Drug Metabolism
https://www.ias.ac.in/article/fulltext/reso/019/03/0259-0282
dealkylation in various substrates [9,10]. The reaction mechanism of CH hydroxylation is shown in Scheme 3. This involves an initial hydrogen abstraction ...
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https://www.ias.ac.in/article/fulltext/reso/019/03/0259-0282
dealkylation in various substrates [9,10]. The reaction mechanism of CH hydroxylation is shown in Scheme 3. This involves an initial hydrogen abstraction ...
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62
HYDRO DEALKYLATION for TOLUENE - DWSIM
https://dwsim.fossee.in/flowsheeting-project/download/project-file/173
The hydrodealkylation of toluene1 (HDA) is a process used to produce BENZENE ,. METHANE and DIPHENYL . Hydrodealkylation is a chemical reaction that often ...
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https://dwsim.fossee.in/flowsheeting-project/download/project-file/173
The hydrodealkylation of toluene1 (HDA) is a process used to produce BENZENE ,. METHANE and DIPHENYL . Hydrodealkylation is a chemical reaction that often ...
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63
Drug-Drug Interactions - Page 281 - Google Books Result
https://books.google.com/books?id=rmCGQ8qAv8AC&pg=PA281&lpg=PA281&dq=o+dealkylation+wiki&source=bl&ots=nZUB3p5aTp&sig=ACfU3U1zRzuOjrkqiMUvyLVlo8I18uH64w&hl=en&sa=X&ved=2ahUKEwi6sL6G9tX7AhWlEVkFHU39BC4Q6AF6BQjmARAD
The final concentration of 8 - methoxypsoralen after the 25 - fold dilution is ... ( phenacetin O - dealkylation ) remains under initial rate conditions .
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https://books.google.com/books?id=rmCGQ8qAv8AC&pg=PA281&lpg=PA281&dq=o+dealkylation+wiki&source=bl&ots=nZUB3p5aTp&sig=ACfU3U1zRzuOjrkqiMUvyLVlo8I18uH64w&hl=en&sa=X&ved=2ahUKEwi6sL6G9tX7AhWlEVkFHU39BC4Q6AF6BQjmARAD
The final concentration of 8 - methoxypsoralen after the 25 - fold dilution is ... ( phenacetin O - dealkylation ) remains under initial rate conditions .
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64
Environmental Health Perspectives: EHP.
https://books.google.com/books?id=bsNf-RG4bo8C&pg=PA171&lpg=PA171&dq=o+dealkylation+wiki&source=bl&ots=TANZT1jB2X&sig=ACfU3U12TC6ICbWaG9iMsb9iBWWu4Fqp-A&hl=en&sa=X&ved=2ahUKEwi6sL6G9tX7AhWlEVkFHU39BC4Q6AF6BQj2ARAD
C - HYDROXYLATION a ) aromatic OH ОН > benzene phenol OH hydroquinone benzoquinone ... H B- Xir WIKI A - - che ཁ –– H R - C -CH2 H P450 RH heme alkylation 6 ...
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https://books.google.com/books?id=bsNf-RG4bo8C&pg=PA171&lpg=PA171&dq=o+dealkylation+wiki&source=bl&ots=TANZT1jB2X&sig=ACfU3U12TC6ICbWaG9iMsb9iBWWu4Fqp-A&hl=en&sa=X&ved=2ahUKEwi6sL6G9tX7AhWlEVkFHU39BC4Q6AF6BQj2ARAD
C - HYDROXYLATION a ) aromatic OH ОН > benzene phenol OH hydroquinone benzoquinone ... H B- Xir WIKI A - - che ཁ –– H R - C -CH2 H P450 RH heme alkylation 6 ...
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65
Sustainable Biofuels: Opportunities and Challenges
https://books.google.com/books?id=9F4BEAAAQBAJ&pg=PA115&lpg=PA115&dq=o+dealkylation+wiki&source=bl&ots=hfGHaJbvna&sig=ACfU3U23Vw9trHT8YwZlXuAm07NV4GYwbQ&hl=en&sa=X&ved=2ahUKEwi6sL6G9tX7AhWlEVkFHU39BC4Q6AF6BQjnARAD
Pt/C removed methoxy moiety to produce 4-propylphenol, ... A limitation of such work was the deactivation of catalyst in the dealkylation reaction.
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https://books.google.com/books?id=9F4BEAAAQBAJ&pg=PA115&lpg=PA115&dq=o+dealkylation+wiki&source=bl&ots=hfGHaJbvna&sig=ACfU3U23Vw9trHT8YwZlXuAm07NV4GYwbQ&hl=en&sa=X&ved=2ahUKEwi6sL6G9tX7AhWlEVkFHU39BC4Q6AF6BQjnARAD
Pt/C removed methoxy moiety to produce 4-propylphenol, ... A limitation of such work was the deactivation of catalyst in the dealkylation reaction.
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