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Google Keyword Rankings for : rini axitinib hypertension
1
Diastolic Blood Pressure as a Biomarker of Axitinib Efficacy in ...
https://aacrjournals.org/clincancerres/article/17/11/3841/12196/Diastolic-Blood-Pressure-as-a-Biomarker-of
Purpose: To evaluate if diastolic blood pressure (dBP) ≥90 mm Hg during axitinib treatment is a marker of efficacy.
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https://aacrjournals.org/clincancerres/article/17/11/3841/12196/Diastolic-Blood-Pressure-as-a-Biomarker-of
Purpose: To evaluate if diastolic blood pressure (dBP) ≥90 mm Hg during axitinib treatment is a marker of efficacy.
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2
Drug-Induced Hypertension Caused by Multikinase Inhibitors ...
https://www.mdpi.com/1422-0067/20/19/4712/htm
Although axitinib promotes slightly higher hypertension rates compared to sunitinib, the overall discontinuation rate and cardiovascular complications are ...
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https://www.mdpi.com/1422-0067/20/19/4712/htm
Although axitinib promotes slightly higher hypertension rates compared to sunitinib, the overall discontinuation rate and cardiovascular complications are ...
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3
Axitinib dose titration: analyses of ... - Annals of Oncology
https://www.annalsofoncology.org/article/S0923-7534(19)34487-4/fulltext
Mean BP across the population was similar when measured in clinic, at home, or by 24-h ABPM. Weak correlations were observed between axitinib steady-state ...
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https://www.annalsofoncology.org/article/S0923-7534(19)34487-4/fulltext
Mean BP across the population was similar when measured in clinic, at home, or by 24-h ABPM. Weak correlations were observed between axitinib steady-state ...
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4
Hypertension as a Biomarker of Efficacy in Patients With ...
https://academic.oup.com/jnci/article/103/9/763/919510
Hypertension (HTN) is an on-target effect of the vascular endothelial growth factor pathway inhibitor, sunitinib.
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https://academic.oup.com/jnci/article/103/9/763/919510
Hypertension (HTN) is an on-target effect of the vascular endothelial growth factor pathway inhibitor, sunitinib.
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5
Incidence and risk of hypertension with a novel multi‐targeted ...
https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bcp.12149
The use of axitinib was associated with significantly increased risk of all grade (RR 3.00, 95% CI 1.29, 6.97, P = 0.011) and high grade ...
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https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bcp.12149
The use of axitinib was associated with significantly increased risk of all grade (RR 3.00, 95% CI 1.29, 6.97, P = 0.011) and high grade ...
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6
Management of Antiangiogenic Therapy-Induced Hypertension
https://www.ahajournals.org/doi/pdf/10.1161/HYPERTENSIONAHA.112.196774
the incidence of hypertension induced by a single antiangio- ... center trials of axitinib in mRCC, nonsmall cell lung cancer, melanoma, and thyroid cancer, ...
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https://www.ahajournals.org/doi/pdf/10.1161/HYPERTENSIONAHA.112.196774
the incidence of hypertension induced by a single antiangio- ... center trials of axitinib in mRCC, nonsmall cell lung cancer, melanoma, and thyroid cancer, ...
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7
Axitinib dose titration: analyses of exposure, blood pressure ...
https://www.sciencedirect.com/science/article/pii/S0923753419344874
Axitinib, a potent, selective tyrosine kinase inhibitor (TKI) of vascular endothelial growth factor (VEGF) receptors (VEGFR) [1], is approved globally for ...
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https://www.sciencedirect.com/science/article/pii/S0923753419344874
Axitinib, a potent, selective tyrosine kinase inhibitor (TKI) of vascular endothelial growth factor (VEGF) receptors (VEGFR) [1], is approved globally for ...
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8
Evaluating the safety and efficacy of axitinib in the treatment of ...
https://www.dovepress.com/evaluating-the-safety-and-efficacy-of-axitinib-in-the-treatment-of-adv-peer-reviewed-fulltext-article-CMAR
The most common grade 3 toxicities are hypertension (16%), diarrhea (11%), ... The second Phase II study of axitinib presented by Rini et al ...
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https://www.dovepress.com/evaluating-the-safety-and-efficacy-of-axitinib-in-the-treatment-of-adv-peer-reviewed-fulltext-article-CMAR
The most common grade 3 toxicities are hypertension (16%), diarrhea (11%), ... The second Phase II study of axitinib presented by Rini et al ...
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9
Axitinib as Second-Line Treatment for Metastatic Renal Cell ...
https://www.theoncologynurse.com/issue-archive/2013-issues/may-2013-vol-6-no-4/15768-axitinib-as-second-line-treatment-for-metastatic-renal-cell-carcinoma
Rini BI, Schiller JH, Fruehauf JP, et al. Diastolic blood pressure as a biomarker of axitinib efficacy in solid tumors. Clin Cancer Res.
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https://www.theoncologynurse.com/issue-archive/2013-issues/may-2013-vol-6-no-4/15768-axitinib-as-second-line-treatment-for-metastatic-renal-cell-carcinoma
Rini BI, Schiller JH, Fruehauf JP, et al. Diastolic blood pressure as a biomarker of axitinib efficacy in solid tumors. Clin Cancer Res.
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10
(PDF) Hypertension among patients with renal cell carcinoma ...
https://www.researchgate.net/publication/260528110_Hypertension_among_patients_with_renal_cell_carcinoma_receiving_axitinib_or_sorafenib_analysis_from_the_randomized_phase_III_AXIS_trial
Hypertension was more frequently observed during treatment with axitinib than ... Brian I. Rini &David I. Quinn &Michael Baum &Laura S. Wood &Jamal Tarazi &.
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https://www.researchgate.net/publication/260528110_Hypertension_among_patients_with_renal_cell_carcinoma_receiving_axitinib_or_sorafenib_analysis_from_the_randomized_phase_III_AXIS_trial
Hypertension was more frequently observed during treatment with axitinib than ... Brian I. Rini &David I. Quinn &Michael Baum &Laura S. Wood &Jamal Tarazi &.
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11
Dr. Rini Describes Hypertension as a Biomarker - OncLive
https://www.onclive.com/view/dr-rini-describes-hypertension-as-a-biomarker-in-rcc
Dr. Brian I. Rini from the Taussig Cancer Institute Describes Hypertension as ... explains results from the AXIS 1032 phase III trial comparing axitinib to ...
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https://www.onclive.com/view/dr-rini-describes-hypertension-as-a-biomarker-in-rcc
Dr. Brian I. Rini from the Taussig Cancer Institute Describes Hypertension as ... explains results from the AXIS 1032 phase III trial comparing axitinib to ...
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12
Pembrolizumab plus Axitinib versus Sunitinib for Advanced ...
https://www.nejm.org/doi/full/10.1056/NEJMoa1816714
Among patients with previously untreated advanced renal-cell carcinoma, treatment with pembrolizumab plus axitinib resulted in significantly ...
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https://www.nejm.org/doi/full/10.1056/NEJMoa1816714
Among patients with previously untreated advanced renal-cell carcinoma, treatment with pembrolizumab plus axitinib resulted in significantly ...
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13
Medline ® Abstract for Reference 115 of 'Toxicity of ...
https://www.uptodate.com/contents/toxicity-of-molecularly-targeted-antiangiogenic-agents-non-cardiovascular-effects/abstract/115
Axitinib dose increases to 7 mg and then to 10 mg, twice daily, were allowed for those patients without hypertension or adverse reactions above grade 2.
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https://www.uptodate.com/contents/toxicity-of-molecularly-targeted-antiangiogenic-agents-non-cardiovascular-effects/abstract/115
Axitinib dose increases to 7 mg and then to 10 mg, twice daily, were allowed for those patients without hypertension or adverse reactions above grade 2.
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14
[PDF] Hypertension among patients with renal cell carcinoma ...
https://www.semanticscholar.org/paper/Hypertension-among-patients-with-renal-cell-or-from-Rini-Quinn/6be2c5b7572152edc238aa3cd4d3005330acfb9b
Hypertension among patients with renal cell carcinoma receiving axitinib or sorafenib: analysis from the randomized phase III AXIS trial · B. Rini, D. Quinn, +8 ...
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https://www.semanticscholar.org/paper/Hypertension-among-patients-with-renal-cell-or-from-Rini-Quinn/6be2c5b7572152edc238aa3cd4d3005330acfb9b
Hypertension among patients with renal cell carcinoma receiving axitinib or sorafenib: analysis from the randomized phase III AXIS trial · B. Rini, D. Quinn, +8 ...
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15
Hypertension as a prognostic factor in metastatic renal cell ...
https://bmcurol.biomedcentral.com/track/pdf/10.1186/s12894-019-0481-5.pdf
Rini BI, Garrett M, Poland B, Dutcher JP, Rixe O, Wilding G, Stadler WM,. Pithavala YK, Kim S, Tarazi J, et al. Axitinib in metastatic renal cell carcinoma:.
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https://bmcurol.biomedcentral.com/track/pdf/10.1186/s12894-019-0481-5.pdf
Rini BI, Garrett M, Poland B, Dutcher JP, Rixe O, Wilding G, Stadler WM,. Pithavala YK, Kim S, Tarazi J, et al. Axitinib in metastatic renal cell carcinoma:.
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16
INLYTA® (axitinib) - Amazon S3
https://s3.amazonaws.com/pfizerpro.com/assets/brand/inlyta/pdfs/nurse_handbook.pdf
Discontinue INLYTA if hypertension is severe and persistent despite use of ... INLYTA® (axitinib) is indicated for the treatment of advanced renal cell ...
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https://s3.amazonaws.com/pfizerpro.com/assets/brand/inlyta/pdfs/nurse_handbook.pdf
Discontinue INLYTA if hypertension is severe and persistent despite use of ... INLYTA® (axitinib) is indicated for the treatment of advanced renal cell ...
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17
Dr. Rini Describes Hypertension as a Biomarker in RCC
https://www.youtube.com/watch?v=YoaJMonyRec
Jul 22, 2011
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https://www.youtube.com/watch?v=YoaJMonyRec
Jul 22, 2011
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18
Biomarkers: Hypertension Following Anti-angiogenesis Therapy
https://www.hematologyandoncology.net/archives/june-2010/renal-cell-carcinoma-in-focus-biomarkers-hypertension-following-anti-angiogenesis-therapy/
Rini BI, Schiller JH, Fruehauf JP, et al. Association of diastolic blood pressure (dBP) >90 mmHg with overall survival (OS) in patients treated with axitinib ( ...
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https://www.hematologyandoncology.net/archives/june-2010/renal-cell-carcinoma-in-focus-biomarkers-hypertension-following-anti-angiogenesis-therapy/
Rini BI, Schiller JH, Fruehauf JP, et al. Association of diastolic blood pressure (dBP) >90 mmHg with overall survival (OS) in patients treated with axitinib ( ...
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19
Axitinib: A Review of its Safety and Efficacy in the Treatment of ...
https://journals.sagepub.com/doi/10.4137/CMO.S10594
The drug related hypertension was resolved under antihypertensive therapy, ... Rini et al reported data on long-term responders to axitinib.
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https://journals.sagepub.com/doi/10.4137/CMO.S10594
The drug related hypertension was resolved under antihypertensive therapy, ... Rini et al reported data on long-term responders to axitinib.
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20
Axitinib versus sorafenib in advanced renal cell carcinoma
https://www.nature.com/articles/bjc2014244
Patients who received prior cytokines had a higher incidence (⩾5% difference) of grade⩾3 hypertension with second-line axitinib or ...
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https://www.nature.com/articles/bjc2014244
Patients who received prior cytokines had a higher incidence (⩾5% difference) of grade⩾3 hypertension with second-line axitinib or ...
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21
Maximizing clinical outcomes with axitinib therapy ... - MDedge
https://cdn.mdedge.com/files/s3fs-public/issues/articles/CO-11_feb%2046_review%20wood.pdf
effects associated with axitinib, such as hypertension, fatigue, and diarrhea, can negatively ... Dr. Rini has received research funding.
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https://cdn.mdedge.com/files/s3fs-public/issues/articles/CO-11_feb%2046_review%20wood.pdf
effects associated with axitinib, such as hypertension, fatigue, and diarrhea, can negatively ... Dr. Rini has received research funding.
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22
Comparative effectiveness of axitinib ... - Northwestern Scholars
https://www.scholars.northwestern.edu/en/publications/comparative-effectiveness-of-axitinib-versus-sorafenib-in-advance
Brian I. Rini*, Bernard Escudier, Piotr Tomczak, Andrey Kaprin, Cezary Szczylik, ... hypertension, and fatigue in the axitinib arm, and diarrhoea, ...
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https://www.scholars.northwestern.edu/en/publications/comparative-effectiveness-of-axitinib-versus-sorafenib-in-advance
Brian I. Rini*, Bernard Escudier, Piotr Tomczak, Andrey Kaprin, Cezary Szczylik, ... hypertension, and fatigue in the axitinib arm, and diarrhoea, ...
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23
Hypertension and angiotensin system inhibitors in patients ...
https://www.frontierspartnerships.org/articles/10.4081/oncol.2016.298/pdf
Bevacizumab Rini et al.18,19. Placebo + IFN 349 28 0 ... of VEGFR-1, -2 and -3.30 In patients with mRCC on axitinib, HTN had an.
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https://www.frontierspartnerships.org/articles/10.4081/oncol.2016.298/pdf
Bevacizumab Rini et al.18,19. Placebo + IFN 349 28 0 ... of VEGFR-1, -2 and -3.30 In patients with mRCC on axitinib, HTN had an.
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24
Time to Resolution of Axitinib-Related Adverse Events After ...
https://www.clinical-genitourinary-cancer.com/article/S1558-7673(21)00082-3/fulltext
For diarrhea, hypertension, nausea, and palmar-plantar erythrodysesthesia syndrome, median TTRs were longer in the axitinib + IO (4-11 days) ...
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https://www.clinical-genitourinary-cancer.com/article/S1558-7673(21)00082-3/fulltext
For diarrhea, hypertension, nausea, and palmar-plantar erythrodysesthesia syndrome, median TTRs were longer in the axitinib + IO (4-11 days) ...
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25
Axitinib-Induced Hypothyroidism as a Predictor of Long-Term ...
https://www.karger.com/Article/Fulltext/499089
Hypertension is a well-known side effect contributing to the outcome of axitinib and sunitinib treatment [9, 10, 11]. Rini et al.
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https://www.karger.com/Article/Fulltext/499089
Hypertension is a well-known side effect contributing to the outcome of axitinib and sunitinib treatment [9, 10, 11]. Rini et al.
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26
Therapeutic effects and associated adverse events of ...
https://www.spandidos-publications.com/10.3892/etm.2015.2427
Previous studies observed that patients suffered hypertension as early as the first day of taking sorafenib (24) and axitinib (25). Rini et ...
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https://www.spandidos-publications.com/10.3892/etm.2015.2427
Previous studies observed that patients suffered hypertension as early as the first day of taking sorafenib (24) and axitinib (25). Rini et ...
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27
Individualized dosing with axitinib: rationale and practical ...
https://www.futuremedicine.com/doi/10.2217/fon-2017-0455
However, Rini et al. demonstrated that increasing the axitinib dose ... Common axitinib-associated AEs, such as diarrhea, hypertension and ...
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https://www.futuremedicine.com/doi/10.2217/fon-2017-0455
However, Rini et al. demonstrated that increasing the axitinib dose ... Common axitinib-associated AEs, such as diarrhea, hypertension and ...
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28
CLINICAL PROTOCOL ADJUVANT AXITINIB TREATMENT ...
https://clinicaltrials.gov/ProvidedDocs/54/NCT01599754/Prot_001.pdf
ADJUVANT AXITINIB TREATMENT OF RENAL CANCER: A RANDOMIZED. DOUBLE-BLIND PHASE 3 STUDY ... Axitinib/Placebo Dose Reduction for Hypertension .
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https://clinicaltrials.gov/ProvidedDocs/54/NCT01599754/Prot_001.pdf
ADJUVANT AXITINIB TREATMENT OF RENAL CANCER: A RANDOMIZED. DOUBLE-BLIND PHASE 3 STUDY ... Axitinib/Placebo Dose Reduction for Hypertension .
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29
Axitinib treatment in patients with cytokine-refractory ...
http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(07)70285-1/abstract
For patients who had persistent or recurrent hypertension after maximum antihypertensive treatment, axitinib dose decrease or interruption, ...
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http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(07)70285-1/abstract
For patients who had persistent or recurrent hypertension after maximum antihypertensive treatment, axitinib dose decrease or interruption, ...
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30
Axitinib Protocol V1.1 - The Clatterbridge Cancer Centre
https://www.clatterbridgecc.nhs.uk/download_file/view/7871/2350
The 'very common' (≥ 1/10) adverse reactions observed following treatment with axitinib are diarrhoea, hypertension, fatigue, decreased ...
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https://www.clatterbridgecc.nhs.uk/download_file/view/7871/2350
The 'very common' (≥ 1/10) adverse reactions observed following treatment with axitinib are diarrhoea, hypertension, fatigue, decreased ...
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31
INLYTA® (axitinib) tablets Fact Sheet | Pfizer
https://cdn.pfizer.com/pfizercom/news/esmo/inlyta_fact_sheet.pdf
outcome and/or blood pressure measurements in patients receiving axitinib with or without dose titration. An additional trial of INLYTA, ...
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https://cdn.pfizer.com/pfizercom/news/esmo/inlyta_fact_sheet.pdf
outcome and/or blood pressure measurements in patients receiving axitinib with or without dose titration. An additional trial of INLYTA, ...
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32
Selenium substituted axitinib reduces axitinib side effects and ...
https://pubs.rsc.org/en/content/articlehtml/2022/ra/d2ra01882a
2C), and the systolic blood pressure of Se-axitinib group was higher than the control group, but lower than axitinib group. Therefore, a weight ...
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https://pubs.rsc.org/en/content/articlehtml/2022/ra/d2ra01882a
2C), and the systolic blood pressure of Se-axitinib group was higher than the control group, but lower than axitinib group. Therefore, a weight ...
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33
What You Need to Know About Axitinib - The ASCO Post
https://ascopost.com/issues/march-15-2012/what-you-need-to-know-about-axitinib/
Severe adverse reactions reported in axitinib patients included hypertensive crisis, arterial and venous thrombotic events, hemorrhage, ...
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https://ascopost.com/issues/march-15-2012/what-you-need-to-know-about-axitinib/
Severe adverse reactions reported in axitinib patients included hypertensive crisis, arterial and venous thrombotic events, hemorrhage, ...
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34
Safety of axitinib and sorafenib monotherapy for patients with ...
https://journal.hep.com.cn/jbr/EN/10.7555/JBR.32.20170080
The overall incidence of high grade hypertension, fatigue, gastrointestinal toxicity and ... Rini BI, Wilding G, Hudes G, Phase II study of axitinib in ...
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https://journal.hep.com.cn/jbr/EN/10.7555/JBR.32.20170080
The overall incidence of high grade hypertension, fatigue, gastrointestinal toxicity and ... Rini BI, Wilding G, Hudes G, Phase II study of axitinib in ...
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35
Risk Factors for the Comorbidity of Hypertension and Renal ...
https://www.frontiersin.org/articles/10.3389/fcvm.2022.810262/full
Firstly, RCC and HTN may have common risk factors, such as obesity, ... sorafenib, pazopanib, axitinib, tivozanib, and cabozantinib (76).
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https://www.frontiersin.org/articles/10.3389/fcvm.2022.810262/full
Firstly, RCC and HTN may have common risk factors, such as obesity, ... sorafenib, pazopanib, axitinib, tivozanib, and cabozantinib (76).
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36
Axitinib in renal cell carcinoma: now what do we do? - Davis
https://tcr.amegroups.com/article/view/2719/html
Although not directly stated in the paper, this information together with a higher rate of hypertension in the axitinib arm suggests that upward dose titration ...
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https://tcr.amegroups.com/article/view/2719/html
Although not directly stated in the paper, this information together with a higher rate of hypertension in the axitinib arm suggests that upward dose titration ...
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37
axitinib.pdf - Cancer Care Ontario
https://www.cancercareontario.ca/en/system/files_force/axitinib.pdf?download=1
Axitinib is VEGF receptor tyrosine kinase inhibitor. ... The most common side effects for axitinib include diarrhea, hypertension, ... Rini BI et al.
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https://www.cancercareontario.ca/en/system/files_force/axitinib.pdf?download=1
Axitinib is VEGF receptor tyrosine kinase inhibitor. ... The most common side effects for axitinib include diarrhea, hypertension, ... Rini BI et al.
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38
Axitinib Shows Clinical Utility in Heavily Pretreated Kidney...
https://journals.lww.com/oncology-times/Fulltext/2007/11250/Axitinib_Shows_Clinical_Utility_in_Heavily.8.aspx
“There is no question that this is an active drug,” said Brian Rini, MD, ... (15%) had Grade 3 or 4 hypertension, and four (7%) had Grade 3 or 4 diarrhea.
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https://journals.lww.com/oncology-times/Fulltext/2007/11250/Axitinib_Shows_Clinical_Utility_in_Heavily.8.aspx
“There is no question that this is an active drug,” said Brian Rini, MD, ... (15%) had Grade 3 or 4 hypertension, and four (7%) had Grade 3 or 4 diarrhea.
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39
Comparative effectiveness of axitinib versus ... - Read by QxMD
https://read.qxmd.com/read/22056247/comparative-effectiveness-of-axitinib-versus-sorafenib-in-advanced-renal-cell-carcinoma-axis-a-randomised-phase-3-trial
Axitinib dose increases to 7 mg and then to 10 mg, twice daily, were allowed for those patients without hypertension or adverse reactions above grade 2.
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https://read.qxmd.com/read/22056247/comparative-effectiveness-of-axitinib-versus-sorafenib-in-advanced-renal-cell-carcinoma-axis-a-randomised-phase-3-trial
Axitinib dose increases to 7 mg and then to 10 mg, twice daily, were allowed for those patients without hypertension or adverse reactions above grade 2.
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40
Axitinib (renal) - SWAG Cancer Alliance
https://www.swagcanceralliance.nhs.uk/wp-content/uploads/2020/09/Axitinib1.pdf
Blood pressure. Must be controlled before initiating axitinib. Urinalysis (to assess for proteinuria). Baseline. ECG/ECHO if patient has significant cardiac ...
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https://www.swagcanceralliance.nhs.uk/wp-content/uploads/2020/09/Axitinib1.pdf
Blood pressure. Must be controlled before initiating axitinib. Urinalysis (to assess for proteinuria). Baseline. ECG/ECHO if patient has significant cardiac ...
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41
BC Cancer Protocol Summary for the Treatment of Metastatic ...
http://www.bccancer.bc.ca/chemotherapy-protocols-site/Documents/Genitourinary/GUAVPEMAX_Protocol.pdf
Cell Carcinoma Using Pembrolizumab and aXitinib. Protocol Code. GUAVPEMAX ... weeks, are normotensive without anti-hypertensive medications, may have dose.
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http://www.bccancer.bc.ca/chemotherapy-protocols-site/Documents/Genitourinary/GUAVPEMAX_Protocol.pdf
Cell Carcinoma Using Pembrolizumab and aXitinib. Protocol Code. GUAVPEMAX ... weeks, are normotensive without anti-hypertensive medications, may have dose.
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42
Hypertension in malignancy–an underappreciated problem
https://www.oncotarget.com/article/25024/text/
In patients with RCC, treatment with pazopanib and sunitinib resulted in a similar incidence of hypertension (46% vs 41%), however axitinib ...
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https://www.oncotarget.com/article/25024/text/
In patients with RCC, treatment with pazopanib and sunitinib resulted in a similar incidence of hypertension (46% vs 41%), however axitinib ...
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43
Safety Profile For INLYTA® (axitinib) | 1st-Line
https://inlyta.pfizerpro.com/inlyta-pembrolizumab/safety-profile
Discontinue INLYTA if hypertension is severe and persistent despite use of antihypertensive therapy and dose reduction of INLYTA, and discontinuation should be ...
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https://inlyta.pfizerpro.com/inlyta-pembrolizumab/safety-profile
Discontinue INLYTA if hypertension is severe and persistent despite use of antihypertensive therapy and dose reduction of INLYTA, and discontinuation should be ...
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44
Pembrolizumab plus Axitinib versus Sunitinib for Advanced ...
https://med-fom-urlgsci.sites.olt.ubc.ca/files/2019/04/nejmsimon2.pdf
Rini at Cleveland Clinic Taussig Cancer. Institute, 9500 Euclid Ave., Desk CA60, ... Pembrolizumab plus Axitinib for Renal-Cell Carcinoma.
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https://med-fom-urlgsci.sites.olt.ubc.ca/files/2019/04/nejmsimon2.pdf
Rini at Cleveland Clinic Taussig Cancer. Institute, 9500 Euclid Ave., Desk CA60, ... Pembrolizumab plus Axitinib for Renal-Cell Carcinoma.
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45
Efficacy and Safety of Axitinib as First-Line Therapy in Japanese ...
https://www.scirp.org/html/6-8902174_58366.htm
22. Rini, B.I., Cohen, D.P., Lu, D.R., Chen, I., Hariharan, S., Gore, M.E., Figlin, R.A., Baum, M.S. and Motzer, R.J. (2011) Hypertension as a Biomarker of ...
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https://www.scirp.org/html/6-8902174_58366.htm
22. Rini, B.I., Cohen, D.P., Lu, D.R., Chen, I., Hariharan, S., Gore, M.E., Figlin, R.A., Baum, M.S. and Motzer, R.J. (2011) Hypertension as a Biomarker of ...
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46
Axitinib for renal cell carcinoma - Australian Prescriber
https://www.nps.org.au/australian-prescriber/articles/axitinib-for-renal-cell-carcinoma
High blood pressure is a problem with axitinib and should be controlled with antihypertensives. In persistent cases, the axitinib dose may need ...
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https://www.nps.org.au/australian-prescriber/articles/axitinib-for-renal-cell-carcinoma
High blood pressure is a problem with axitinib and should be controlled with antihypertensives. In persistent cases, the axitinib dose may need ...
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47
KEYNOTE-426 Final Analysis - Clinical Care Options
https://www.clinicaloptions.com/-/media/oncology/conferences/2021/clinical-oncology-2021/gu/cco_clinical_oncology_2021_4500.pptx?rev=df41c6bb54f940d38b9d246ffc212395
Rini. ASCO 2021. Abstr 4500. Slide credit: clinicaloptions.com. Response. (ITT Population). Pembro + Axitinib.
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https://www.clinicaloptions.com/-/media/oncology/conferences/2021/clinical-oncology-2021/gu/cco_clinical_oncology_2021_4500.pptx?rev=df41c6bb54f940d38b9d246ffc212395
Rini. ASCO 2021. Abstr 4500. Slide credit: clinicaloptions.com. Response. (ITT Population). Pembro + Axitinib.
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48
Axitinib plus pembrolizumab in patients with advanced renal ...
https://www.ejcancer.com/article/S0959-8049(20)31419-2/fulltext
Axitinib plus pembrolizumab showed superior overall survival (OS), ... hypertension (53.8%), cough (48.1%) and dysphonia (48.1%).
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https://www.ejcancer.com/article/S0959-8049(20)31419-2/fulltext
Axitinib plus pembrolizumab showed superior overall survival (OS), ... hypertension (53.8%), cough (48.1%) and dysphonia (48.1%).
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49
Rini Compares Upfront Immune-Based Regimens for Renal ...
https://www.targetedonc.com/view/rini-compares-upfront-immune-based-regimens-for-renal-cell-carcinoma
Median follow-ups are obviously different, with ipilimumab/ nivolumab now having 5-year follow-up with the most recent publication, axitinib/ ...
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https://www.targetedonc.com/view/rini-compares-upfront-immune-based-regimens-for-renal-cell-carcinoma
Median follow-ups are obviously different, with ipilimumab/ nivolumab now having 5-year follow-up with the most recent publication, axitinib/ ...
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50
Axitinib: Treatment of Metastatic Renal Cell Cancer
https://www.urology-textbook.com/axitinib.html
Axitinib is an oral potent inhibitor of VEGF receptor tyrosine kinases 1–3, which thus inhibits the intracellular signal transduction of cell growth, ...
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https://www.urology-textbook.com/axitinib.html
Axitinib is an oral potent inhibitor of VEGF receptor tyrosine kinases 1–3, which thus inhibits the intracellular signal transduction of cell growth, ...
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51
Time to Resolution of Axitinib-Related ... - Physician's Weekly
https://www.physiciansweekly.com/time-to-resolution-of-axitinib-related-adverse-events-after-treatment-interruption-in-patients-with-advanced-renal-cell-carcinoma/
Any grade and grade ≥3 treatment-emergent diarrhea, fatigue, hypertension, nausea, and palmar-plantar erythrodysesthesia syndrome were assessed ...
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https://www.physiciansweekly.com/time-to-resolution-of-axitinib-related-adverse-events-after-treatment-interruption-in-patients-with-advanced-renal-cell-carcinoma/
Any grade and grade ≥3 treatment-emergent diarrhea, fatigue, hypertension, nausea, and palmar-plantar erythrodysesthesia syndrome were assessed ...
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52
cancer - Elsevier e-Prints |
https://es.ereprints.elsevier.cc/sites/es.ereprints.elsevier.cc/files/filefield_paths/fogli_english.pdf
Romano Danesia,⁎, Brian I. Rinic, Manuela Schmidingerd ... with axitinib who develop a diastolic blood pressure ≥90 mmHg were.
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https://es.ereprints.elsevier.cc/sites/es.ereprints.elsevier.cc/files/filefield_paths/fogli_english.pdf
Romano Danesia,⁎, Brian I. Rinic, Manuela Schmidingerd ... with axitinib who develop a diastolic blood pressure ≥90 mmHg were.
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53
Individualization of Dose and Schedule Based On Toxicity for ...
https://content.iospress.com/download/kidney-cancer/kca190077?id=kidney-cancer%2Fkca190077
a summary of available data for axitinib, pazopanib, cabozantinib and sorafenib. SUNITINIB ... come in mRCC patients that developed hypertension,.
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https://content.iospress.com/download/kidney-cancer/kca190077?id=kidney-cancer%2Fkca190077
a summary of available data for axitinib, pazopanib, cabozantinib and sorafenib. SUNITINIB ... come in mRCC patients that developed hypertension,.
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54
KEYNOTE-426: Pembrolizumab and axitinib vs sunitinib in ...
https://ecancer.org/en/video/7689-keynote-426-pembrolizumab-and-axitinib-vs-sunitinib-in-advanced-renal-cell-carcinoma
› video › 7689-keynote-426-pembroli...
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https://ecancer.org/en/video/7689-keynote-426-pembrolizumab-and-axitinib-vs-sunitinib-in-advanced-renal-cell-carcinoma
› video › 7689-keynote-426-pembroli...
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55
Optimizing Patient Adherence to Targeted Therapies in Renal Cell ...
https://www.ons.org/pubs/article/234041/download
Eisen, et al., 2007; Motzer et al., 2007; Rini, Escudier, et al., 2011; ... of incidence, hypertension appears more common with axitinib.
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https://www.ons.org/pubs/article/234041/download
Eisen, et al., 2007; Motzer et al., 2007; Rini, Escudier, et al., 2011; ... of incidence, hypertension appears more common with axitinib.
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56
Original Article Association of axitinib plasma exposure and genetic ...
https://nagoya.repo.nii.ac.jp/record/23418/files/article.pdf
concentration-time curve (AUC) of axitinib and diastolic blood pressure correlate with ... Rini et al. showed that patients who achieved 1- to 2- hour ...
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https://nagoya.repo.nii.ac.jp/record/23418/files/article.pdf
concentration-time curve (AUC) of axitinib and diastolic blood pressure correlate with ... Rini et al. showed that patients who achieved 1- to 2- hour ...
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57
Renal Cell Carcinoma: Molecular Targets and Clinical ...
https://books.google.com/books?id=NYqeBQAAQBAJ&pg=PA232&lpg=PA232&dq=rini+axitinib+hypertension&source=bl&ots=lBETPIRk3f&sig=ACfU3U1hn04OTxh96vf6xkdvtP7Ka-Tjkg&hl=en&sa=X&ved=2ahUKEwjesLeitdb7AhWwmGoFHYh5C3kQ6AF6BQjaARAD
Therefore, axitinib has the strongest clinical data in patients who failed ... Treatment-induced hypertension is the leading toxicity in patients treated ...
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https://books.google.com/books?id=NYqeBQAAQBAJ&pg=PA232&lpg=PA232&dq=rini+axitinib+hypertension&source=bl&ots=lBETPIRk3f&sig=ACfU3U1hn04OTxh96vf6xkdvtP7Ka-Tjkg&hl=en&sa=X&ved=2ahUKEwjesLeitdb7AhWwmGoFHYh5C3kQ6AF6BQjaARAD
Therefore, axitinib has the strongest clinical data in patients who failed ... Treatment-induced hypertension is the leading toxicity in patients treated ...
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58
Cardio-Oncology: Principles, Prevention and Management
https://books.google.com/books?id=xwnpCgAAQBAJ&pg=PA76&lpg=PA76&dq=rini+axitinib+hypertension&source=bl&ots=GGbbU7xx9n&sig=ACfU3U1lp7qhTUfrXH562rxqLlb7iUrMGg&hl=en&sa=X&ved=2ahUKEwjesLeitdb7AhWwmGoFHYh5C3kQ6AF6BQjbARAD
Axitinib is associated with a significant increase in cases of hypertension, as demonstrated by a recent meta-analysis of Abdel-Rahman where the subgroup of ...
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https://books.google.com/books?id=xwnpCgAAQBAJ&pg=PA76&lpg=PA76&dq=rini+axitinib+hypertension&source=bl&ots=GGbbU7xx9n&sig=ACfU3U1lp7qhTUfrXH562rxqLlb7iUrMGg&hl=en&sa=X&ved=2ahUKEwjesLeitdb7AhWwmGoFHYh5C3kQ6AF6BQjbARAD
Axitinib is associated with a significant increase in cases of hypertension, as demonstrated by a recent meta-analysis of Abdel-Rahman where the subgroup of ...
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59
Journal of the National Cancer Institute: JNCI.
https://books.google.com/books?id=2BVYr4uSQOYC&pg=PA1558&lpg=PA1558&dq=rini+axitinib+hypertension&source=bl&ots=vmUnp0QtLz&sig=ACfU3U20rDbZ6UHShIazEwzE4l0XbJ-8IQ&hl=en&sa=X&ved=2ahUKEwjesLeitdb7AhWwmGoFHYh5C3kQ6AF6BQjgARAD
IC ) ; Pfizer spective analysis of hypertension ( HTN ) lication regarding ... most mechanism of treatment - induced HTN Correspondence to : Brian I. Rini ...
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https://books.google.com/books?id=2BVYr4uSQOYC&pg=PA1558&lpg=PA1558&dq=rini+axitinib+hypertension&source=bl&ots=vmUnp0QtLz&sig=ACfU3U20rDbZ6UHShIazEwzE4l0XbJ-8IQ&hl=en&sa=X&ved=2ahUKEwjesLeitdb7AhWwmGoFHYh5C3kQ6AF6BQjgARAD
IC ) ; Pfizer spective analysis of hypertension ( HTN ) lication regarding ... most mechanism of treatment - induced HTN Correspondence to : Brian I. Rini ...
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60
2014 Oncology Nursing Drug Handbook
https://books.google.com/books?id=sM2FAgAAQBAJ&pg=PA495&lpg=PA495&dq=rini+axitinib+hypertension&source=bl&ots=e5FhA4IY7z&sig=ACfU3U3CMCYOdSMHgHI0rrooOY3dwkcUmw&hl=en&sa=X&ved=2ahUKEwjesLeitdb7AhWwmGoFHYh5C3kQ6AF6BQjhARAD
... with a delayed deterioration in quality oflife (Rini et al, 2011; ... IN CIRCULATION related to HYPERTENSION Defining Characteristics: Axitinib ...
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https://books.google.com/books?id=sM2FAgAAQBAJ&pg=PA495&lpg=PA495&dq=rini+axitinib+hypertension&source=bl&ots=e5FhA4IY7z&sig=ACfU3U3CMCYOdSMHgHI0rrooOY3dwkcUmw&hl=en&sa=X&ved=2ahUKEwjesLeitdb7AhWwmGoFHYh5C3kQ6AF6BQjhARAD
... with a delayed deterioration in quality oflife (Rini et al, 2011; ... IN CIRCULATION related to HYPERTENSION Defining Characteristics: Axitinib ...
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61
2013 Oncology Nursing Drug Handbook
https://books.google.com/books?id=kNXAsXnelfsC&pg=PA528&lpg=PA528&dq=rini+axitinib+hypertension&source=bl&ots=NVIMsQkBwn&sig=ACfU3U3FcPIsyFK1Ri9wXEa9SwQ8KinXSg&hl=en&sa=X&ved=2ahUKEwjesLeitdb7AhWwmGoFHYh5C3kQ6AF6BQjWARAD
Mild to severe hypertension may also be present. MRI is necessary to confirm a diagnosis of RPLS. Discontinue axitinib in patients who are developing RPLS ...
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https://books.google.com/books?id=kNXAsXnelfsC&pg=PA528&lpg=PA528&dq=rini+axitinib+hypertension&source=bl&ots=NVIMsQkBwn&sig=ACfU3U3FcPIsyFK1Ri9wXEa9SwQ8KinXSg&hl=en&sa=X&ved=2ahUKEwjesLeitdb7AhWwmGoFHYh5C3kQ6AF6BQjWARAD
Mild to severe hypertension may also be present. MRI is necessary to confirm a diagnosis of RPLS. Discontinue axitinib in patients who are developing RPLS ...
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