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1 Insights into beta cell regeneration for diabetes via integration ...
https://www.nature.com/articles/s41467-017-00992-9
Although diabetes results in part from a deficiency of normal pancreatic beta cells, inducing human beta cells to regenerate is difficult.
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2 Pancreatic β Cell Regeneration as a Possible Therapy for ...
https://www.sciencedirect.com/science/article/pii/S1550413117304928
This review focuses on endogenous regeneration, which can follow two pathways: enhanced replication of existing β cells and formation of new β ...
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3 Endogenous Pancreatic β Cell Regeneration: A Potential ...
https://www.frontiersin.org/articles/10.3389/fendo.2019.00101/full
Endogenous pancreatic β cell regeneration is a potential strategy for β cell expansion or neogenesis to treat diabetes.
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4 Current Status of Islet Cell Replacement and Regeneration ...
https://academic.oup.com/jcem/article/95/3/1034/2596567
Context: Β cell mass and function are decreased to varying degrees in both type 1 and type 2 diabetes. In the future, islet cell replacement or regeneration ...
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5 cell regeneration as an effective anti-diabetic therapy
https://www.cell.com/cell-reports/pdf/S2211-1247(22)00647-7.pdf
Here, we discover the b-cell regenerative effects of glucagon receptor ... models of type 2 diabetes mellitus (Gu et al., 2009; Solloway.
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6 Cell Proliferation Is Severely Restricted With Advanced Age
https://diabetes.diabetesjournals.org/content/58/6/1365.full.pdf
Young rodents may not faithfully model the regenerative capacity of -cells in mature adult mice. Diabetes 58:1365–1372, 2009. -Cell mass normally grows well ...
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7 Regenerative Medicine for Diabetes Mellitus - SAGE Journals
https://journals.sagepub.com/doi/10.1177/096368970901805-602
Moreover, the number of pancreatic β-cells is also low in type 2 diabetes, caused by the compounding factors of insulin secretory failure and insulin resistance ...
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8 Oxidative Stress in Pancreatic Beta Cell Regeneration - Hindawi
https://www.hindawi.com/journals/omcl/2017/1930261/
Pancreatic β cell neogenesis and proliferation during the neonatal period are critical for the generation of sufficient pancreatic β cell mass/ ...
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9 Advances in β cell replacement and regeneration strategies ...
https://www.jci.org/articles/view/87439
Manipulating these targets or the pathways they regulate could be a strategy for promoting the expansion of residual β cells in diabetic ...
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10 β cell regeneration and novel strategies for
https://www.spandidos-publications.com/10.3892/br.2022.1555/download
Abstract. The etiology of diabetes is primarily attributed to the lack of functioning β cells, which in‑turn leads to insulin defi‑.
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11 β-cell regeneration and differentiation: how close are we to the ...
https://jme.bioscientifica.com/view/journals/jme/53/3/R119.xml
Keywords: development; diabetes (all); islet cells; insulin; ... 2009). Secondly, procedures for purifying the desired cell types or for selecting against ...
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12 Islet Regeneration: Endogenous and Exogenous Approaches
https://www.mdpi.com/1422-0067/22/7/3306/htm
Both type 1 and type 2 diabetes are characterized by a progressive loss of beta cell mass that contributes to impaired glucose homeostasis.
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13 β-Cell Regeneration Mediated by Human Bone Marrow ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042177
Sustained reversion of diabetes mediated by hBMSCs-VEGF was secondary to endogenous β-cell regeneration and correlated with activation of ...
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14 Reviewing Major Mechanisms of β-Cell Regeneration
https://gmr.scholasticahq.com/article/12643-reviewing-major-mechanisms-of-cell-regeneration-a-prospective-treatment-for-diabetes-mellitus
Regeneration of human pancreatic β cells has the direct ability to treat type 1 and type 2 diabetes mellitus because important ...
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15 β-cell preservation and regeneration for diabetes treatment
https://www.openaccessjournals.com/articles/bcell-preservation-and-regeneration-for-diabetes-treatment-where-are-we-now.pdf
Diabetes Manage. (2012) 2(3), 213–222. SUMMARY Over the last decade, our knowledge of β-cell biology has expanded with the use of new scientific techniques ...
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16 Advances in β cell replacement and ... - Sander Lab
http://msanderlab.org/wp-content/uploads/2017/07/Benthuysen-2016-review.pdf
Introduction. Diabetes mellitus is a chronic disease affecting an estimated 422 million people worldwide in 2014 (1). Characterized by elevated.
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17 Polycomb protein Ezh2 regulates pancreatic β-cell Ink4a/Arf ...
http://genesdev.cshlp.org/content/23/8/975
Our discovery of Ezh2-dependent β-cell proliferation revealed unique epigenetic mechanisms underlying normal β-cell expansion and β-cell regenerative failure in ...
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18 Insulin-producing β-cells regenerate ectopically from a ... - eLife
https://elifesciences.org/articles/65758
Surprisingly, β-cell regeneration increased markedly in npas4l mutants owing to the ectopic differentiation of β-cells in the mesenchyme, a ...
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19 evidence for β-cell turnover and regeneration from sources of ...
https://journals.physiology.org/doi/full/10.1152/ajpendo.00284.2009
As described previously, this rat model of type 2 diabetes has ER-stress induced β-cell apoptosis that leads to a progressive deficit in β-cell mass and ...
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20 Pancreatic beta cell function persists in many patients with ...
https://link.springer.com/article/10.1007/s00125-009-1342-7
Some native pancreatic beta cell function persists even years after disease onset in most type 1 diabetic patients. However, if prolonged ...
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21 Exocrine pancreas regeneration modifies original ... - Science
https://www.science.org/doi/10.1126/scitranslmed.abg9170
Insulin deficiency in type 1 diabetes results from destruction of pancreatic β cells, and therapeutic strategies focus on trying to restore ...
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22 Human Pancreatic Beta Cell Regeneration for Diabetes
https://www.youtube.com/watch?v=eNDpDwIOqpk
Icahn School of Medicine
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23 Type 2 Diabetes and the Aging Pancreatic Beta Cell
https://www.aging-us.com/full/100350
Here we review how aging affects the proliferative and regenerative capacity of beta cells and how this impacts beta cell mass.
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24 The effects of plant-based diets on pancreatic beta-cell function
https://diabetesonthenet.com/journal-diabetes-nursing/effects-plant-based-diets-pancreatic-beta-cell-function-systematic-review/
A 2009 analysis of the Adventist Health Study-2 revealed that the ... diet promotes Ngn3-driven β-cell regeneration to reverse diabetes.
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25 Evaluation of the Effect of an Advance Diabetes Support ...
https://www.sciencerepository.org/evaluation-of-the-effect-of-an-advance_RGM-2022-1-103
It is supposed that beta cells can regenerate from reproduction of pre-existing beta cells or through neogenesis of stem cells and progenitor cells on the ...
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26 IGFBP1 increases β‐cell regeneration by promoting α
https://www.embopress.org/doi/10.15252/embj.201592903
There is great interest in therapeutically harnessing endogenous regenerative mechanisms to increase the number of β cells in people with diabetes.
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27 Imaging Beta Cell Regeneration and Interactions with Islet ...
https://www.liebertpub.com/doi/10.1089/zeb.2012.0813
After genetic ablation, beta cells are initially dysfunctional or dying, and blood glucose levels increase fourfold. During a 2-week period, ...
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28 Stem Cell-Derived Beta Cells for Treatment of Type 1 Diabetes?
https://www.thelancet.com/article/S2352-3964(14)00020-6/fulltext
Beta cells both produce insulin and sense glucose and calibrate the delivery of appropriate amounts of insulin without causing hypoglycemia or ...
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29 In vivo generation and regeneration of β cells in zebrafish
https://cellregeneration.springeropen.com/articles/10.1186/s13619-020-00052-6
The pathological feature of diabetes, hyperglycemia, is a result of an inadequate number and/or function of insulin producing β cells.
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30 A single-cell atlas of de novo β-cell regeneration reveals the ...
http://biorxiv.org/cgi/reprint/2021.06.24.449704v1
The transcriptomic analysis of β-cell regeneration reveals that ... the ability of zebrafish to reverse the course of diabetes. Results.
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31 Regeneration of Islet Beta-Cells from Stem Cells and ...
https://austinpublishinggroup.com/stemcell-research-transplantation/fulltext/jscrt-v1-id1001.php
The diabetes population sizes increasing rapidly all over the world. The transplant of insulin-producing β-cells into diabetic patients is considered to be a ...
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32 Beta-cell failure in type 2 diabetes: mechanisms, markers, and ...
https://www.tandfonline.com/doi/full/10.1080/00325481.2020.1771047
A decline in pancreatic beta-cell function has been defined as a key contributing factor to progression of T2D. In fact, a significant proportion of beta-cell ...
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33 Glucagon blockade restores functional β-cell mass in type 1 ...
https://www.pnas.org/content/118/9/e2022142118
Both type 1 and type 2 diabetes are associated with reduced β-cell mass or function, resulting from decreased proliferation and increased ...
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34 DRI Scientists Identify Unique Pancreatic Stem Cells with the ...
https://diabetesresearch.org/dri-scientists-identify-unique-pancreatic-stem-cells-with-the-potential-to-regenerate-beta-cells-that-respond-to-glucose/
DRI Scientists Identify Unique Pancreatic Stem Cells with the Potential to Regenerate Beta Cells that Respond to Glucose · Pancreatic progenitor ...
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35 Regenerative Medicine and Tissue Engineering for the ...
https://www.intechopen.com/books/tissue-engineering-for-tissue-and-organ-regeneration/regenerative-medicine-and-tissue-engineering-for-the-treatment-of-diabetes
Regeneration of beta cells in the original pancreas could be an ideal cure for type 1 diabetic patients. Since the neural relay system can stimulate beta cell ...
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36 β-cell Regenerative Potential of Selected Herbal Extracts in ...
http://www.eurekaselect.com/161386/article
Background: Effective β-cell regeneration is a recognized therapeutic strategy in the treatment of type 1 diabetes mellitus. Regeneration of β-cells could ...
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37 Understanding generation and regeneration of pancreatic β ...
https://journals.biologists.com/dev/article/147/7/dev179051/223051/Understanding-generation-and-regeneration-of
Type 1 diabetes (T1D), which accounts for 5-10% of cases, is caused by insufficient secretion of insulin due to attack of β cells by the immune ...
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38 Advances in [beta] cell replacement and regeneration ... - Gale
https://link.gale.com/apps/doc/A466615787/HRCA?u=googlescholar&sid=googleScholar&xid=33ae7259
Finally, recent studies have revealed novel pharmacologic targets for stimulating [beta] cell replication. Manipulating these targets or the pathways they ...
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39 Effects of High-Density Lipoproteins on Pancreatic β-Cell ...
https://www.ahajournals.org/doi/full/10.1161/ATVBAHA.110.207373
The UK Prospective Diabetes Study found that at the time of disease diagnosis, β-cell secretory function was about 50% of normal and predicted ...
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40 Microfluidic-Based Beta-Cell Functional Analysis Facility
https://surgery.virginia.edu/surgical-research-at-uva/microfluidic-based-beta-cell-functional-analysis-facility/
The overall purpose is to assist the field of diabetes research in moving forward with therapeutic strategies for beta-cell replacement and beta-cell ...
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41 Pancreatic beta-cells - MPG.PuRe
https://pure.mpg.de/rest/items/item_587601/component/file_587600/content
Stem cells. Regeneration. Mouse. Diabetes. a b s t r a c t. The pancreas is composed of two main compartments consisting of endocrine and ...
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42 Pancreatic Regeneration Models, Mechanisms, and ...
https://www.pancreapedia.org/reviews/pancreatic-regeneration-models-mechanisms-and-inconsistencies
The adult pancreas displays a limited capacity to regenerate, ... (STZ) are used to induce diabetes by chemical ablation of pancreatic β-cells.
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43 Novel Therapy to Preserve Beta Cell Function in New Onset ...
https://clinicaltrials.gov/ct2/show/NCT00837759
Brief Summary: Background: Type 1 diabetes (T1D) occurs when the immune system attacks insulin-producing cells (beta cells) in the pancreas, resulting in ...
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44 Advances in β cell replacement and ... - Europe PMC
https://europepmc.org/article/med/27694741
In the past decade, new approaches have been explored that are aimed at restoring functional β cell mass as a treatment strategy for diabetes.
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45 Pancreatic beta cell protection/regeneration with phytotherapy
https://www.scielo.br/j/bjps/a/FKXz8XsxcW9YcNh3MTrHMZL/?lang=en
Considering the physiopathology of diabetes, preventing beta cell degeneration and stimulating the endogenous regeneration of islets will be essential ...
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46 Beta cell regeneration in human pancreas | Request PDF
https://www.researchgate.net/publication/49711838_Beta_cell_regeneration_in_human_pancreas
The sensu strictiori definition of beta cells implies replacement of lost beta cell mass by new beta cells. In our discussion, however, we will ...
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47 Islet Regeneration - Center for Regenerative Biotherapeutics
https://www.mayo.edu/research/centers-programs/center-regenerative-biotherapeutics/focus-areas/islet-regeneration
Glucose-responsive, insulin-secreting cells in the islets (beta cells) are dysfunctional in both type 1 and type 2 diabetes. In type 1 diabetes, beta cells are ...
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48 A focus on beta cell mass could help prevent type 2 diabetes
https://researchoutreach.org/articles/focus-beta-cell-mass-could-help-prevent-type-2-diabetes/
When insulin production drops too far and glucose levels become too high, then the patient is diagnosed with diabetes, and at this point the ...
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49 beta-cells | The Stem Cellar
https://blog.cirm.ca.gov/tag/beta-cells/
Patients with Type I Diabetes are unable to control blood glucose levels because their immune system attacks insulin-producing beta cells, which are responsible ...
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50 Sangeeta Dhawan, Ph.D. - City of Hope
https://www.cityofhope.org/people/sangeeta-dhawan
Both type 1 and type 2 diabetes result from the loss of beta cells, making beta cell replenishment a very important therapeutic goal. Approaches to this end ...
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51 Beta Cell Regeneration - ASweetLife
https://asweetlife.org/the-regeneration-of-beta-cells/
A new diabetes study co-funded by JDRF has found that alpha cells in the pancreas can regenerate themselves into insulin-producing beta ...
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52 Beta-Cell Regeneration: Definition and Overview - DSM
https://www.diabetesselfmanagement.com/diabetes-resources/definitions/beta-cell-regeneration/
Beta-cell regeneration is a natural process that creates new beta cells, which make and secrete insulin in the pancreas. Diabetes ...
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53 Brennand K, Melton D. Slow and steady is the key to beta-cell ...
https://hscrb.harvard.edu/publication/brennand-k-melton-d-slow-and-steady-is-the-key-to-beta-cell-replication-j-cell-mol-med-2009-mar-133472-87/
The beta-cells of the pancreas are responsible for insulin production and their destruction results in type I diabetes. beta-cell maintenance, growth and ...
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54 Diabetic retinopathy - Wikipedia
https://en.wikipedia.org/wiki/Diabetic_retinopathy
Diabetic retinopathy is a medical condition in which damage occurs to the retina due to diabetes mellitus. It is a leading cause of blindness in developed ...
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55 sign in to your account - UW System Admissions Application
https://apply.wisconsin.edu/sign-in
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56 Insulin-Producing Beta-Cell Regeneration Driven by ...
https://www.genengnews.com/news/insulin-producing-beta-cell-regeneration-driven-by-circadian-clock-controls-diabetes-in-mice/
Diabetes is characterized by partial destruction of the pancreatic islet β-cells that produce insulin, and regenerating these cells ...
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57 Forms - NJ Courts
https://www.njcourts.gov/self-help/forms
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58 Application for Health Coverage - WV Chip
https://chip.wv.gov/SiteCollectionDocuments/Health%20Insurance-Single%20Streamlined%20Application.pdf
(You can still apply for health insurance even if you don't file a federal income tax return.) NO. If no, skip to question c. b. C. YES ...
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59 the State of Delaware Health and Social Services (DHSS)
https://www.dhss.delaware.gov/dhss/dss/files/form100e.pdf
If you are applying for medical assistance and file taxes, we need to know about everyone on your tax return. Race: B = Black/African American. W=White.
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60 Application for Health Coverage & Help Paying Costs - NJ.gov
https://www.nj.gov/corrections/pdf/OTS/FRARA/NJFamilyCare/NJ%20FAmily%20Care%20Application.pdf
b. Will you claim any dependents on your tax return? Yes No. If yes, list name(s) of dependents: c. Will you be claimed as a dependent on someone's tax ...
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https://graduate.wou.edu/

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https://www.dowjones.com/professional/factiva/
Advanced Analytics & Data Mining. Generate deeper insights, improve sentiment analysis, uncover hidden relationships, accurately forecast and enrich data ...
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64 How to Increase Your Red Blood Cell Count - Healthline
https://www.healthline.com/health/how-to-increase-red-blood-cells
Iron. Iron is essential for the production of RBCs. · Folic acid. Getting enough B vitamins in your diet may also be beneficial. · Vitamin B12. Foods high in ...
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65 Illinois State Police Home Page
https://isp.illinois.gov/

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66 Subscriber Agreement Electronic (NYSE)-TDA 1122
https://www.tdameritrade.com/retail-en_us/resources/pdf/TDA5056.pdf
MARKET DATA DEFINITION – For all purposes of this Agreement, "Market ... admitted to dealings on the New York Stock Exchange ("NYSE*"), (b) such bond and ...
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67 Regulation of cell and gene therapy products in Japan | RAPS
https://www.raps.org/news-and-articles/news-articles/2021/8/regulation-of-cell-and-gene-therapy-products-in-ja
The society cited the use of adipose-derived mesenchymal stem cells for the treatment of diabetes as a practice that could undermine confidence in regenerative ...
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68 Welcome to the Jefferson Libraries
https://library.jefferson.edu/

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69 Path2College 529 Plan
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70 The New York Times - Breaking News, US News, World News ...
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71 Office of the Registrar: Academic Calendar - JMU
https://www.jmu.edu/registrar/academic-calendar.shtml
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73 Administrative law | Attorney-General's Department
https://www.ag.gov.au/legal-system/administrative-law
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78 Bullying and the peer group: A review
https://njbullying.org/documents/bullyingandpeergrroup.pdf
Available online 6 September 2009. Keywords: Bullying. Victimization. Participant roles. Peer group. Classroom context. It is often stated that bullying is ...
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79 ShopUW+ Essentials – UW System Purchasing and Payables ...
https://shopuwplus.wisc.edu/

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80 Honda Owners Site | Tips, Tools & Benefits for Honda Owners
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82 Online Cybersecurity Degree – Bachelor's Degrees | WGU
https://www.wgu.edu/online-it-degrees/cybersecurity-information-assurance-bachelors-program.html
This means you can finish as many courses as you're able in a term at no additional cost. WHAT ABOUT TRANSFER CREDITS? Secure Systems Analysis & ...
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88 Commercial Vehicles ׀ Vans, Pick-ups & Trucks ׀ Fiat ...
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89 Transplantation, Bioengineering, and Regeneration of the ...
https://books.google.com/books?id=cG-9DwAAQBAJ&pg=PA209&lpg=PA209&dq=diabetes+beta+cell+regeneration+explained+2009&source=bl&ots=cRmTWlqIc6&sig=ACfU3U0AR8aHYh180cS1Sq-eTi1C2SouCg&hl=en&sa=X&ved=2ahUKEwj-xP-z8db7AhXU7GEKHYK9AyoQ6AF6BQjYAhAD
Adaptive beta-cell proliferation is severely restricted with advanced age. Diabetes. 2009;58(6):1365–1372. 22. Gunasekaran U, Gannon M. Type 2 diabetes and ...
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90 The Zebrafish: Cellular and Developmental Biology, Part A
https://books.google.com/books?id=rgD7ABqAt2MC&pg=PA278&lpg=PA278&dq=diabetes+beta+cell+regeneration+explained+2009&source=bl&ots=LKqztc-6v9&sig=ACfU3U08kLwtfHPOkOVNI3f_z3Y27ulUqw&hl=en&sa=X&ved=2ahUKEwj-xP-z8db7AhXU7GEKHYK9AyoQ6AF6BQjIAhAD
Kinkel, M. D., and Prince, V. E. (2009). On the diabetic menu: Zebrafish as a model for pancreas development and function. Bioessays 31, 139–152.
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91 International Textbook of Diabetes Mellitus
https://books.google.com/books?id=O4AxBwAAQBAJ&pg=PA158&lpg=PA158&dq=diabetes+beta+cell+regeneration+explained+2009&source=bl&ots=Y3DcyNvDOE&sig=ACfU3U3-KG78BZauYdhrJj86MMzHmDDiiQ&hl=en&sa=X&ved=2ahUKEwj-xP-z8db7AhXU7GEKHYK9AyoQ6AF6BQjMAhAD
Thorens B: Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1. PNAS 1992;89:8641–8645.
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92 Frontiers in Skeletal Muscle Wasting, Regeneration and Stem ...
https://books.google.com/books?id=mI1ADgAAQBAJ&pg=PA238&lpg=PA238&dq=diabetes+beta+cell+regeneration+explained+2009&source=bl&ots=YcVGHnX51N&sig=ACfU3U38rRXr7rNi94R9nDJArWgdO4Uj3g&hl=en&sa=X&ved=2ahUKEwj-xP-z8db7AhXU7GEKHYK9AyoQ6AF6BQjKAhAD
Diabetes 53, 25–31. doi:10.2337/diabetes.53.1.25 Allen, D. L., Cleary, A. S., ... role in the development of insulin resistance and beta-cell dysfunction.
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93 Principles of Regenerative Medicine - Google Books Result
https://books.google.com/books?id=Wd_wNMFBDxQC&pg=PT440&lpg=PT440&dq=diabetes+beta+cell+regeneration+explained+2009&source=bl&ots=m5TNBIy8I9&sig=ACfU3U1EfonRyKawY5uHJmmCefoRsSRbjA&hl=en&sa=X&ved=2ahUKEwj-xP-z8db7AhXU7GEKHYK9AyoQ6AF6BQjJAhAD
The effect of medical therapy and islet cell transplantation on diabetic nephropathy: ... (2009). Islet autotransplantation after distal pancreatectomy for ...
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94 Diabetes: Damages and Treatments - Page 64 - Google Books Result
https://books.google.com/books?id=HrqZDwAAQBAJ&pg=PA64&lpg=PA64&dq=diabetes+beta+cell+regeneration+explained+2009&source=bl&ots=TmwYtgt7ri&sig=ACfU3U3Ru3ckdjDfffmiLj4bfykVc6YMSQ&hl=en&sa=X&ved=2ahUKEwj-xP-z8db7AhXU7GEKHYK9AyoQ6AF6BQjWAhAD
The success of recent clinical trials for allogeneic islet ... is showing that the beta-cell replacement therapy for the treatment of patients with diabetes ...
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