Master Regulator Of Immune System

Google Keyword Rankings for : master regulator of immune system

1 Immunoregulatory molecules are master regulators ... - PubMed
https://pubmed.ncbi.nlm.nih.gov/22819828/
Different molecules have a key role in the regulation of the immune system, including the receptors PD-1 (Programmed cell Death 1), CTLA-4 ( ...
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2 Dendritic Cells: Master Regulators of the Immune Response
https://aacrjournals.org/cancerimmunolres/article/1/3/145/466591/Dendritic-Cells-Master-Regulators-of-the-Immune
Dendritic cells (DC) are responsible for initiating all antigen-specific immune responses. As such, they are the master regulators of the ...
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3 NKG2D: A Master Regulator of Immune Cell Responsiveness
https://www.frontiersin.org/articles/10.3389/fimmu.2018.00441/full
NKG2D is an activating receptor that is mostly expressed on cells of the cytotoxic arm of the immune system. Ligands of NKG2D are normally ...
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4 STAT3, a Master Regulator of Anti-Tumor Immune Response
https://www.mdpi.com/2072-6694/11/9/1280
Immune cells in the tumor microenvironment regulate cancer growth. Thus cancer progression is dependent on the activation or repression of transcription ...
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5 MYC: Master Regulator of Immune Privilege - Cell Press
https://www.cell.com/trends/immunology/pdf/S1471-4906(17)30013-3.pdf
MYC: Master Regulator of ... Oncogenic MYC Addiction and the Immune System ... by the immune system in a clinically effective manner through the alteration ...
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6 STING: a master regulator in the cancer-immunity cycle
https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-019-1087-y
Current studies show that STING activation facilitates the antitumor immune response in most conditions; however, emerging studies also suggest ...
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7 Powerful Immune “Master Regulator” Is Behind Antibody ...
https://www.technologynetworks.com/immunology/news/powerful-immune-master-regulator-is-behind-antibody-development-336436
The new study, published recently in Nature Immunology, shows how a protein works as a “master regulator” in the immune system. The research is ...
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8 The mucosal immune system: master regulator of bidirectional ...
https://www.nature.com/articles/nrgastro.2016.191
Although adaptive immunity (T cells in particular) participates in this process, there is an emerging role for cells of the innate immune ...
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9 Cyclic AMP | Master Regulator of Innate Immune Cell Function
https://www.atsjournals.org/doi/10.1165/rcmb.2008-0091TR
cAMP is now recognized as a universal regulator of cellular function in organisms including amoebas, plants, and humans (1). Biological ...
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10 Is nuclear sirtuin SIRT6 a master regulator of immune function?
https://journals.physiology.org/doi/10.1152/ajpendo.00483.2020
Emerging evidence suggests that Myc family members play essential roles in regulating the development, differentiation, and activation of immune cells (173).
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11 Toll-like receptor co-receptors as master regulators of the ...
https://www.sciencedirect.com/science/article/pii/S0161589014001205
PRRs govern these processes, regulating the activation of a complex network of transcription factors able to induce the appropriate immune response to a ...
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12 How a master regulator in ovarian cancer can go from helpful ...
https://www.sciencedaily.com/releases/2016/02/160211140436.htm
When it comes to our immune system, dendritic cells serve as a sort of lighthouse for T-cells. These specialized immune cells break down cancer ...
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13 Network-based identification of key master regulators ...
https://academic.oup.com/bib/article/22/6/bbab168/6274817
A cancer immune phenotype characterized by an active T-helper 1 (Th1)/cytotoxic response is associated with responsiveness to immunotherapy and ...
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14 Training the Immune Response: B-cells' Master Regulator
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.0020226
› plosbiology › article › journa...
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15 MicroRNA-155: A Master Regulator of Inflammation
https://www.liebertpub.com/doi/10.1089/jir.2018.0155
Several studies have analyzed which form of mature miR-155 (miR-155-5p or miR-155-3p) is important for immune response and regulation of ...
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16 Study identifies master regulator behind the development of ...
https://www.news-medical.net/news/20210924/Study-identifies-master-regulator-behind-the-development-of-antibody-producing-cells.aspx
The master regulator behind the development of antibody-producing cells has been identified in a study by investigators at Weill Cornell ...
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17 Wnt Signaling as a Master Regulator of Immune Tolerance in ...
https://www.intechopen.com/chapters/64232
Emerging studies have shown that Wnt signaling is a key pathway regulating tolerance versus immunity, and that it is a master regulator of T cell immune ...
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18 IL-10: The Master Regulator of Immunity to Infection
https://journals.aai.org/jimmunol/article/180/9/5771/78405/IL-10-The-Master-Regulator-of-Immunity-to
by KN Couper · 2008 · Cited by 2437 —
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19 Cytokines and transcription factors (the master regulators are ...
https://www.researchgate.net/figure/Cytokines-and-transcription-factors-the-master-regulators-are-underlined_tbl1_223986940
CD4⁺T cells are crucial in achieving a regulated effective immune response to pathogens. Naive CD4⁺T cells are activated after interaction with antigen-MHC ...
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20 C5aR1 is a master regulator in Colorectal Tumorigenesis via ...
https://www.thno.org/v10p8619.htm
The complement system has been recognized as a prominent arsenal of innate immunity and a bridge to adaptive immunity for immune surveillance and homeostasis [7 ...
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21 The MYC oncogene is a master regulator of immune response
https://lymphomahub.com/medical-information/aacr-2017-or-the-myc-oncogene-is-a-master-regulator-of-immune-response-myc-inactivation-presents-a-potential-curative-option-for-lymphoma
AACR 2017 | The MYC oncogene is a master regulator of immune response: MYC inactivation presents a potential curative option for Lymphoma · Original text.
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22 Using Flow Cytometry to Immunophenotype Dendritic Cells
https://fcslaboratory.com/master-regulators-of-the-immune-system/
Dendritic cells (DC) are specialized antigen-presenting cells and key mediators of immunity and tolerance. DC bridge the innate and adaptive immune systems.
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23 A Master Regulator That Helps Power Immune Cells on the ...
https://www.labroots.com/trending/immunology/22470/master-regulator-boosts-energy-immune-cells-attack
When pathogens infect cells, the immune system has to launch a counterattack. Scientists have now learned more about how immune cells boost ...
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24 Master Transcription Regulators and Transcription Factors ...
https://www.ghadvances.org/article/S2772-5723(22)00011-5/fulltext
We further demonstrate that molecules called “master transcriptional regulators” (MTRs) play a critical role in regulating the expression of ...
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25 The MYC oncogene is a global regulator of the immune ...
https://ashpublications.org/blood/article/131/18/2007/36721/The-MYC-oncogene-is-a-global-regulator-of-the
The mechanism by which MYC regulates the immune response was not clear. Recently, multiple groups described that MYC family members regulate the ...
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26 High-mobility group box 1 (HMGB1) as a master regulator of ...
https://link.springer.com/article/10.1007/s00441-010-1033-1
HMGB1 is released upon cell and tissue necrosis and is actively produced by immune cells. Evidence suggests that HMGB1 acts as a key molecule of ...
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27 Dendritic cells: master regulators of the immune response.
https://europepmc.org/article/med/24777676
Dendritic cells (DC) are responsible for initiating all antigen-specific immune responses. As such, they are the master regulators of the immune response ...
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28 HIF-1α: a master regulator of innate host defenses? - JCI
https://www.jci.org/articles/view/25740
In the days following infection, when the human body develops and refines antibodies and prepares to mount an adaptive immune response, ...
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29 Immunity -- master regulator of liver metabol | EurekAlert!
https://www.eurekalert.org/news-releases/690897
They are metabolic powerhouses in the healthy organism, but they also serve as important immune signaling platforms during infections. As such, ...
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30 The Sin3a repressor complex is a master regulator of ... - PNAS
https://www.pnas.org/doi/10.1073/pnas.1206458109
Sin3a is instead required for IFN-stimulated gene (ISGs) transcription and an efficient antiviral response. Our results unveil a critical role for the Sin3a ...
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31 Immune master regulator orchestrates responses to parasite ...
https://www.sanger.ac.uk/news_item/immune-master-regulator-orchestrates-responses-parasite-infection/
› news_item › immune-maste...
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32 Bcl-6 'Master Regulator' Discovery Sheds Light on ...
https://sjogrenssyndromenews.com/news/bcl-6-master-regulator-discovery-sheds-light-on-autoimmune-diseases-such-as-sjogrens/
Researchers have discovered the mechanisms by which Bcl-6 — a protein that is considered a “master regulator” of the immune system ...
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33 Genetic Controller Prepares Immune System for Diverse Threats
https://www.hhmi.org/news/genetic-controller-prepares-immune-system-diverse-threats
Scientists have identified a genetic regulator that controls the reshuffling of gene segments in immune cells. An army of immune cells ...
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34 Researchers Discover Human Immune System Has ...
https://health.ucsd.edu/news/2010/Pages/12-20-innate-immune-system.aspx
A molecule known as nuclear factor kappa B (NF-κB) has been regarded as the “master regulator” of the body's innate immune response, ...
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35 Master transcription regulators and ... - RCSI Repository
https://repository.rcsi.com/articles/journal_contribution/Master_transcription_regulators_and_transcription_factors_regulate_immune-associated_differences_between_patients_of_African_and_European_ancestry_with_colorectal_cancer/19950353
Master transcription regulators and transcription factors regulate immune-associated differences between patients of African and European ...
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36 NKG2D: A Master Regulator of Immune Cell ... - ReadCube
https://www.readcube.com/articles/10.3389/fimmu.2018.00441
NKG2D is an activating receptor that is mostly expressed on cells of the cytotoxic arm of the immune system. Ligands of NKG2D are normally of low abundance, ...
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37 Fur Is the Master Regulator of the Extraintestinal Pathogenic ...
https://journals.asm.org/doi/10.1128/mBio.01460-14
The major change in gene expression induced by serum—active and inactive—involved metabolic genes. In particular, the serum metabolic response ...
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38 p21 is a master regulator of NF-ÎºB-dependent inflammation in ...
https://www.walshmedicalmedia.com/proceedings/p21-is-a-master-regulator-of-nfbdependent-inflammation-in-immune-disease-and-allergic-asthma-10005.html
The first association of p21 with the immune response was its identification as an autoimmunity suppressor, and it was assumed to control T cell proliferation.
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39 Biology and therapeutic potential of interleukin-10
https://rupress.org/jem/article/217/1/e20190418/132577/Biology-and-therapeutic-potential-of-interleukin
The wide range of IL-10–producing and IL-10–responding cells offers the immune system the possibility of regulating the immune response in different situations ...
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40 Foxp3 - Wikipedia
https://en.wikipedia.org/wiki/FOXP3
Regulatory T cells generally turn the immune response down. In cancer, an excess of regulatory T cell activity can prevent the immune system from destroying ...
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41 Transcriptional regulation of plant innate immunity
https://portlandpress.com/essaysbiochem/article/doi/10.1042/EBC20210100/231450/Transcriptional-regulation-of-plant-innate
Transcriptional reprogramming is an integral part of plant immunity. Tight regulation of the immune transcriptome is essential for a proper ...
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42 Studies Reveal an Immune System Regulator
https://www.nytimes.com/2007/04/27/us/27immune.html
The regulatory network may provide new clues to both the working of the body's immune defenses and the generation of a class of cancers known as ...
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43 FoxP3 Program - Sapience Therapeutics, Inc.
https://www.sapiencetherapeutics.com/pipeline/foxp3-program
Forkhead box p3 (FoxP3) is a protein involved in regulation of immune system responses. FoxP3 functions as a master regulator for the development and ...
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44 STING: a master regulator in the cancer-immunity cycle
https://d-nb.info/1205647171/34
In this review, we focus on STING and the cancer immune response and elaborate on the master roles of STING activation in regulating the cancer-immunity cycle.
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45 Microglial Master Regulator Tunes AD Risk Gene Expression ...
https://www.alzforum.org/news/research-news/microglial-master-regulator-tunes-ad-risk-gene-expression-age-onset
Recent genetic findings have highlighted the contributions of the immune system to Alzheimer's disease pathogenesis.
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46 Master regulator genes and their impact on major diseases
https://peerj.com/articles/9952/
Master regulator genes (MRGs) have become a hot topic in recent decades. They not only affect the development of tissue and organ systems ...
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47 CDI Lab Discovers Novel Mechanism of Immune 'Memory ...
https://hmh-cdi.org/2022/02/23/cdi-lab-discovers-novel-mechanism-of-immune-memory-with-vaccine-implications/
Taken all together, the master regulator is crucial in the body responding to threats it has seen before, either through infection or via ...
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48 New Insights Into the Control of Inflammation
https://wistar.org/news/press-releases/new-insights-control-inflammation
“Our data suggest EGR1 acts as a master regulator of inflammation in ... white blood cells of the immune system called monocytes can leave ...
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49 Master regulator of liver metabolism ... - Medical Xpress
https://medicalxpress.com/news/2019-11-master-liver-metabolism-infection.html
They are metabolic powerhouses in the healthy organism, but they also serve as important immune signaling platforms during infections. As such, ...
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50 MicroRNAs: master regulators in host–parasitic protist ...
https://royalsocietypublishing.org/doi/10.1098/rsob.210395
Importantly, targets genes of dysregulated miRNAs are involved in immune response-related signalling pathways (i.e. Rap1, MAPK and Hippo ...
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51 2022.02.22.481404v1.full.pdf - bioRxiv
https://www.biorxiv.org/content/10.1101/2022.02.22.481404v1.full.pdf
Keywords: Tumor Immunology, T regulatory Cells, Master Regulator Analysis, ... and tolerogenic (pro-tumor) immune cell function in the.
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52 Transcription factor regulatory network for early lung immune ...
https://www.spandidos-publications.com/10.3892/mmr.2015.3721
TFs involvement in the regulation of immune system processes ... Ezh2 and Klf4 as master regulators of early lung response to tuberculosis.
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53 CD4+T Cells: Differentiation and Functions - Hindawi
https://www.hindawi.com/journals/jir/2012/925135/
CD4+T cells are crucial in achieving a regulated effective immune response to pathogens. Naive CD4+T cells are activated after interaction with antigen-MHC ...
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54 T-bet as a master regulator of mucosal immunity and ...
https://app.dimensions.ai/details/grant/grant.4107113
T-bet as a master regulator of mucosal immunity and inflammatory bowel disease. Funder: Medical Research Council (MRC). Grant number: MR/M003493/1 ...
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55 TFEB is a master regulator of tumor-associated macrophages ...
https://jitc.bmj.com/content/8/1/e000543
Conclusions Our study identifies TFEB as a master regulator of TAMs in breast cancer. TFEB controls TAM gene expression and function through multiple ...
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56 T-bet as a master regulator of mucosal immunity ... - GtR - UKRI
https://gtr.ukri.org/project/D5D8A280-0B95-4234-8C6A-1A9BE8678515
One of these molecules, (T-bet) stands out as a potentially important regulator of gut immune cells. It is abnormally expressed in IBD patients ...
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57 Revisiting the role of the Gcm transcription factor, from master ...
https://www.tandfonline.com/doi/abs/10.1080/19336934.2016.1212793
Gcm was first described as the master gene of the glial fate in Drosophila as it induces the differentiation of neuroblasts into glia in the developing nervous ...
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58 Immune Master Regulator Orchestrates Responses to ...
https://www.infectioncontroltoday.com/view/immune-master-regulator-orchestrates-responses-parasite-infection
Unravelling this signalling mechanism will help scientists understand immune response to other parasites and will shed light on pathways ...
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59 Structure and Mechanism of a Master Regulator of Cell Fate in ...
https://medicine.yale.edu/event/mbandb-seminar-structure-and-mechanism-of-a-master-regulator-of-cell-fate-in-the-immune-system/
MB&B Seminar: "Structure and Mechanism of a Master Regulator of Cell Fate in the Immune System: Sometimes Two Heads are Better than One".
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60 LincRNA-immunity landscape analysis identifies EPIC1 as a ...
https://www.science.org/doi/10.1126/sciadv.abb3555
By further using in vivo and in vitro cancer models, we aimed to identify and mechanistically validate lincRNAs that are master regulators of tumor immune ...
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61 RUI: Control of CIITA Function and Immune System Gene ...
https://www.nsf.gov/awardsearch/showAward?AWD_ID=0212067
Central to inducing this immune response is the activation of the master regulator factor, the class II transactivator (CIITA). CIITA acts in the nucleus of ...
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62 Dendritic Vaccines - Robust Cell Count & Viability Assessments
https://chemometec.com/resources/industry/dendritic-vaccines/
Dendritic cells (DCs) can stimulate antigen-specific T cell responses and are the most potent antigen-presenting cell (APC) of the human immune system, ...
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63 Learning and memory … and the immune system
http://learnmem.cshlp.org/content/20/10/601.full
The nervous system can therefore be viewed as the master regulator of homeostasis. In this role, however, it does not act alone. The immune system, through its ...
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64 Research | IFM Therapeutics
https://www.ifmthera.com/research/
Furthermore, since adaptive immune system pathways are powerful and common to most ... response and the master regulator of subsequent immune activity.
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65 Identification of Master Regulator Genes in Human Periodontitis
http://journals.sagepub.com/doi/10.1177/0022034516653588
Our analyses identified 41 consensus master regulator genes (MRs), ... Pathways related to immune system signaling and development were the ones most ...
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66 Masterswitch discovered in body's immune system
https://www.manchester.ac.uk/discover/news/masterswitch-discovered-in-bodys-immune-system/
The 10-year-study found that microRNA-142 controls Regulatory T cells, which modulate the immune system and prevent autoimmune disease. It is, ...
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67 IL-23: The Master Regulator Behind Plaque Psoriasis - WIRED
https://www.wired.com/wiredinsider/2019/10/il-23-vs-plaque-psoriasis/
Imagine if your immune system was a symphony orchestra lead by a conductor. The conductor's job is to direct the groups of instruments to play together in ...
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68 Revisiting the role of the Gcm transcription factor, from master ...
https://hal.archives-ouvertes.fr/hal-03376912
Master genes are known to induce the differentiation of a multipotent cell into a specific cell type. These molecules are often transcription factors that ...
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69 IRF-7 is the master regulator of type-I interferon-dependent ...
https://go.gale.com/ps/i.do?id=GALE%7CA185471459&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=00280836&p=HRCA&sw=w
Thus, all elements of IFN responses, whether the systemic production of IFN in innate immunity or the local action of IFN from plasmacytoid dendritic cells in ...
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70 Structure of immune-regulating ubiquitin ligase solved
https://www.sbpdiscovery.org/news/beaker-blog/structure-of-immune-regulating-ubiquitin-ligase-solved
“NF-kB is the master regulator of inflammation inside cells, and its activation is believed to promote cancer development by inhibiting cell ...
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71 Cytokines Regulating Immune System - Sino Biological
https://www.sinobiological.com/research/cytokines/cytokines-regulating-immune-system
The master regulator transcription factor is GATA3, which can be upregulated via IL-4 action and STAT-6. IL-4 is sufficient, but is not the only necessary ...
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72 Regulating the regulators of the immune system - Penn Today
https://penntoday.upenn.edu/news/regulating-regulators-immune-system
The findings reveal a complexity to how the body “regulates the regulators” of the immune system, says Hunter. “Once you have those Tregs to ...
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73 Immune regulation - YouTube
https://www.youtube.com/watch?v=qjkxVRBTVY0
HIV-NAT Thailand
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74 Drug triggers immune cells to attack prostate cancer
https://medicine.wustl.edu/news/drug-triggers-immune-cells-to-attack-prostate-cancer/
Many genes have several roles in the body, and ACK1's roles in expression of the androgen receptor and in reigning in the immune system make it ...
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75 Immune Cell Activiation & Proliferation - Sartorius
https://www.sartorius.com/en/applications/life-science-research/cell-analysis/live-cell-assays/cell-movement-morphology/immune-cell-activation-proliferation
These dynamic changes in cell number and cell-cell interactions are fundamental to regulating the effect and extent of the immune response.
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76 15 Foods That Boost the Immune System - Healthline
https://www.healthline.com/health/food-nutrition/foods-that-boost-the-immune-system
Sunflower seeds are full of nutrients, including phosphorous, magnesium, and vitamins B-6 and E. Vitamin E is important in regulating and ...
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77 TransCode Therapeutics Announces eIND ... - Yahoo Finance
https://www.yahoo.com/now/transcode-therapeutics-announces-eind-submission-120000095.html
... microRNA-10b, described as the master regulator of metastasis in a number ... to drive an immune response in the tumor microenvironment; ...
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78 Biosciences Faculty Database
https://biosciences.stanford.edu/faculty/biosciences-faculty-database/
› faculty › biosciences-f...
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79 TransCode Therapeutics Announces eIND ... - BioSpace
https://www.biospace.com/article/releases/transcode-therapeutics-announces-eind-submission-to-us-fda-for-planned-first-in-human-clinical-trial-in-patients-with-advanced-solid-tumors/
... microRNA-10b, described as the master regulator of metastasis in a ... an immune response in the tumor microenvironment; TTX-CRISPR, ...
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80 Pyroptosis and Cervical Cancer | Encyclopedia MDPI
https://encyclopedia.pub/entry/37226
Of which, IL-1β is a key effector molecule in initiating host innate immune response and has a strong immune stimulatory activity. Abnormal ...
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81 Florida Department of Health
https://www.floridahealth.gov/
Medical Exemption from COVID-19 Vaccination · Religious Exemption from COVID-19 Vaccination · Exemption from COVID-19 Vaccination Based on COVID-19 Immunity ...
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82 Infection and Immunity - Utrecht University
https://www.uu.nl/en/masters/infection-and-immunity
This Master's programme covers a variety of topics such as fundamental and clinical immunology, vaccines, immunotherapy, mechanisms of infectious diseases, ...
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83 Mushroom magic: why the latest health fad might be on to ...
https://www.theguardian.com/society/2019/jan/16/mud-wtr-mushroom-water-coffee-health-benefits
We took a look at the science behind the claims of immune support, ... in reishi mushrooms may strengthen the immune system to fight cancer.
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84 Superfund Law's Exemptions Elusive as EPA Pushes PFAS ...
https://news.bloomberglaw.com/environment-and-energy/superfund-laws-exemptions-elusive-as-epa-pushes-pfas-actions
EPA's regulation “would put every [water] utility in the country at ... Cancer, heart problems, weakened immune systems, and other health ...
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85 CDI Laboratory Identifies Critical Regulators Controlling T-Cell ...
https://www.hackensackmeridianhealth.org/en/News/2022/08/11/CDI-Laboratory-Identifies-Critical-Regulators-Controlling-TCell-Homeostasis
... and Innovation (CDI) could hold the key to better modulating the human immune system to fight cancer and produce vaccines of the future.
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86 Viome Life Sciences debuts Full Body Intelligence Test
https://www.nutraingredients.com/Article/2022/07/26/viome-life-sciences-debuts-full-body-intelligence-test
“You can think of these as the master regulators of various important functions ... inflammation response, immune system health, gut health, ...
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87 Masturbation: The positive and negative effects on the brain
https://www.medicalnewstoday.com/articles/masturbation-effects-on-brain
... responses to reproduction, stress management, and emotional regulation. ... of prolactin and endocannabinoids, which help regulate the immune system.
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88 Revealing druggable cryptic pockets in the Nsp1 of SARS ...
https://elifesciences.org/articles/81167
... of the translation-mediated innate immune response in host cells, ... biological function as both are involved in the regulation of the ...
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89 transcode therapeuti - MarketScreener
https://www.marketscreener.com/quote/stock/TRANSCODE-THERAPEUTICS-I-122045496/news/TransCode-Therapeutics-Announces-eIND-Submission-to-US-FDA-for-Planned-First-in-Human-Clinical-Trial-42441763/
... microRNA-10b, described as the master regulator of metastasis in a number ... to drive an immune response in the tumor microenvironment; ...
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90 Quercetin: Benefits, Side Effects, and Sources - Health
https://www.health.com/quercetin-health-benefits-6825553
Studies regarding quercetin and immune function have had mixed results, ... improvements in both hormone and insulin regulation.18.
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91 FL HealthSource • Health Care Resources for Consumers ...
https://flhealthsource.gov/
Veterans Application for Licensure Online Response System. Learn more » · DataPortal. Public Data Portal. Access downloadable files on the MQA Health Care ...
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92 Restoring myocardial infarction-induced long-term memory ...
https://www.thelancet.com/pdfs/journals/ebiom/PIIS2352-3964(22)00566-7.pdf
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