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1 Professor Irwin McLean - University of Dundee
https://www.dundee.ac.uk/people/irwin-mclean
Irwin McLean was Professor of Genetic Medicine at The University of Dundee ... the importance of skin barrier function in preventing atopic eczema and paved ...
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2 Eczema genetics: current state of knowledge and ... - PubMed
https://pubmed.ncbi.nlm.nih.gov/19209157/
Increased understanding of genetic predisposition in atopy and eczema has directed interest toward key pathogenic ... Sara J Brown , W H Irwin McLean ...
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3 Irwin McLean - Wikipedia
https://en.wikipedia.org/wiki/Irwin_McLean
Irwin McLean ; Scientific career ; Scientific career · Inherited skin diseases · Atopic eczema · Keratinocyte biology; Drug discovery · Gene silencing therapy ...
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4 Irwin McLean - Professor Emeritus in Genetic Medicine
https://uk.linkedin.com/in/irwin-mclean-9837bb11
Irwin McLean PhD DSc FRS FRSE FMedSci MAE FRSB FRSA is a retired biomedical research scientist now working in the voluntary sector and as a creativewriter ...
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5 Filaggrin failure – from ichthyosis vulgaris to atopic eczema ...
https://onlinelibrary.wiley.com/doi/abs/10.1111/bjd.14997
W.H. Irwin McLean. ... Conflicts of interest None delcared. Read the full text. About. Figures ...
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6 Eczema Genetics: Current State of Knowledge and Future Goals
https://www.sciencedirect.com/science/article/pii/S0022202X15342482
Increased understanding of genetic predisposition in atopy and eczema has ... In 2006, a group led by Prof Irwin McLean (University of Dundee) reported that ...
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7 Irwin McLean - Royal Society
https://royalsociety.org/people/irwin-mclean-11934/
Irwin McLean is investigating the genetic basis of inherited skin diseases. His primary interest lies in the gene that encodes filaggrin, a protein that ...
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8 Irwin MCLEAN | PhD, DSc, FRS, FRSE, FMedSci
https://www.researchgate.net/profile/Irwin-Mclean
Irwin MCLEAN, Professor of Human Genetics; Head of Division (Molecular Medicine); Scientific Director (DGEM) | Cited by 31697 | of University of Dundee, ...
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9 ‪Irwin McLean‬ - ‪Google Scholar‬
https://scholar.google.com/citations?user=zdV-AHMAAAAJ&hl=en
Emeritus Professor of Genetic Medicine, University of Dundee - ‪‪Cited by 40220‬‬ - ‪Genetics‬ - ‪Dermatology‬ - ‪Filaggrin‬ - ‪Keratin‬ - ‪Eczema‬
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10 New Findings Back Eczema Gene Link - ScienceDaily
https://www.sciencedaily.com/releases/2006/09/060925080323.htm
In March this year, a group lead by Irwin McLean discovered a major gene (filaggrin) that causes atopic dermatitis (commonly known as ...
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11 Patents by Inventor William Henry Irwin McLean
https://patents.justia.com/inventor/william-henry-irwin-mclean
William Henry Irwin McLean has filed for patents to protect the following ... susceptibility to other diseases including atopic dermatitis (eczema), asthma, ...
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12 Eczema Genetics: Current State of Knowledge and Future Goals
https://librarysearch.hillsdale.edu/discovery/fulldisplay?docid=cdi_openaire_primary_oai_dnet_base_oa_6dba37fd71b8a0b1aa3846c8497de97d&context=PC&vid=01HC_INST:01HC_INST&lang=en&search_scope=MyInst_and_CI&adaptor=Primo%20Central&query=null%2C%2CCase%20studies.%2CAND&facet=citedby%2Cexact%2Ccdi_FETCH-LOGICAL-1564t-869217e7045511ea584392faffbd92102ec97bf5ed72fd18ed006b335ff1e21b3&offset=10
Increased understanding of genetic predisposition in atopy and eczema has directed interest toward key pathogenic ... Brown, Sara J. ; Irwin McLean, W.H..
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13 Irwin McLean - AD Scientific Index 2023
https://www.adscientificindex.com/scientist.php?id=1332433
Irwin McLean University of Dundee. Irwin McLean. AD Scientific Index 2023 ... Genetics | Dermatology | Filaggrin | Keratin | Eczema |, #1 (20) *, #26 Top 2%
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14 McLean William Henry Irwin - Academy of Europe
https://www.ae-info.org/ae/User/McLean_William_Henry_Irwin
... Keratins; Filaggrin; Atopic eczema; Cytoskeleton/structural molecules; Therapy development/experimental medicine. Honours and Awards.
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15 Professor (William Henry) Irwin McLean
https://acmedsci.ac.uk/fellows/fellows-directory/ordinary-fellows/fellow/Professor-(William-Henry)-Irwin-McLean-0009124
inherited skin disease, atopic eczema, keratinocyte biology, drug discovery, ... Irwin McLean is Professor of Human Genetics at the University of Dundee.
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16 JCI - Old King Coal — molecular mechanisms underlying an ...
https://www.jci.org/articles/30898
W.H. Irwin McLean1 and Alan D. Irvine2,3,4 ... understanding of why topical coal tar is an effective treatment for atopic dermatitis (AD), ...
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17 Filaggrin failure – from ichthyosis vulgaris to atopic eczema ...
https://academic.oup.com/bjd/article-pdf/175/S2/4/45777854/bjd0004.pdf
W.H. Irwin McLean. ... major genetic predisposing factor for atopic dermatitis (eczema) and all ... pathophysiology of eczema and allergy.
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18 The allergy gene: how a mutation in a skin protein revealed a ...
https://facultyopinions.com/prime/reports/m/3/2/
W. H. Irwin McLeanemail. View more. View less ... Atopic eczema is the most common, inflammatory skin condition, affecting 20% of children.
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19 ‪Irwin McLean‬ - ‪Google 学术搜索‬
https://scholar.google.ae/citations?user=zdV-AHMAAAAJ&hl=zh-CN
Emeritus Professor of Genetic Medicine, University of Dundee - ‪‪引用次数:40759 次‬‬ - ‪Genetics‬ - ‪Dermatology‬ - ‪Filaggrin‬ - ‪Keratin‬ - ‪Eczema‬
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20 Organization, structure, and polymorphisms of the human ...
https://pubs.acs.org/doi/10.1021/bi00492a018
... W H Irwin McLean, Alan D. Irvine. Intragenic Copy Number Variation within Filaggrin Contributes to the Risk of Atopic Dermatitis with a ...
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21 One Remarkable Molecule: Filaggrin - University of ... - UMBrella
https://umbrella.lib.umb.edu/discovery/fulldisplay?docid=cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3378480&context=PC&vid=01MA_UMB:01MA_UMB&lang=en&search_scope=MyInst_and_CI&adaptor=Primo%20Central&tab=Everything&query=null%2C%2CNew%20York%20%3A%20McGraw-Hill%20Irwin%2CAND&mode=advanced
... vulgaris—the most common disorder of keratinization—and also a strong genetic risk factor for atopic eczema, ... Brown, Sara J. ; Irwin McLean, W.H..
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22 Dry skin and the fliaggrin gene and Eczema
https://www.eczema.org.au/dry-skin-and-the-fliaggrin-gene-and-eczema/
Dry skin and atopic eczema: the filaggrin story… what does it mean to you? This publication from Professor Irwin McLean's group, shows that lack of the ...
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23 Research grant for eczema drugs
https://news.st-andrews.ac.uk/archive/research-grant-for-eczema-drugs/
Professor Irwin McLean of Dundee University's College of Medicine, Dentistry and Nursing said, “This is a really exciting opportunity to ...
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24 Gene-Environment Interaction in the Onset of Eczema in Infancy
https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0050131
Irwin Mclean, ... Eczema is a skin condition characterized by dry, red, ... Eczema is associated with asthma and allergy, though allergy ...
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25 McLean/Heagerty 1 (2014) - DEBRA UK
https://www.debra.org.uk/preclinical-studies-towards-application-of-sirna-therapy-in-epidermolysis-bullosa-simplex
Investigator: Professor W. H. Irwin McLean, Professor of Human Genetics ... are the major genetic predisposing factor for atopic eczema and ...
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26 Filaggrin null mutations and childhood atopic eczema: A population ...
https://x.cnki.net/kcms/detail/detail.aspx?dbname=GARJ0010_4&filename=SJES04D6E2AE6335BD6D43FC5279544348E6&dbcode=WWJD&v=w9ipa2Ze6d1phRVkFW4VtpYVPIUzQ8INK%mmd2Fv1GM1qOuu825nf44Ytyg503niGRMGhAZYzOWJBhDJ2N64d0d0KUFNTaKq1kTK%mmd2F
Sara J. BrownCaroline L. ReltonHaihui LiaoYiwei ZhaoAileen SandilandsIan J. WilsonJohn BurnNick J. ReynoldsW. H. Irwin McLeanHeather J. Cordell.
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27 Paper - Filaggrin and eczema
https://www.rcpe.ac.uk/sites/default/files/weller.pdf
ECZEMA. Atopic dermatitis is an itchy skin condition, generally affecting the flexures and starting ... In April 2006, a paper by Irwin McLean's group from.
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28 Find out more about filaggrin | National Eczema Society
https://eczema.org/information-and-advice/our-skin-and-eczema/find-out-more-about-filaggrin/
... until 2006 that its critical role in developing the skin barrier was described by a remarkable geneticist from Dundee, called Professor Irwin McLean.
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29 Comprehensive analysis of the gene encoding filaggrin ...
https://read.qxmd.com/read/17417636/comprehensive-analysis-of-the-gene-encoding-filaggrin-uncovers-prevalent-and-rare-mutations-in-ichthyosis-vulgaris-and-atopic-eczema
... uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema ... Colin N A Palmer, Frances J D Smith, W H Irwin McLean, Alan D Irvine.
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30 Prevalent and Rare Mutations in the Gene Encoding Filaggrin ...
https://www.kidney-international.org/article/S0022-202X(15)34332-3/fulltext
Irwin McLean has filed patents relating to genetic testing and therapy development aimed at the filaggrin gene. ACKNOWLEDGMENTS. We thank the patients and their ...
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31 Current Perspectives Series: Filaggrin in Atopic Dermatitis
http://www.tara.tcd.ie/handle/2262/50585
Grainne M. O Regan, Aileen Sandilands, WH Irwin McLean and Alan D. Irvine, Current Perspectives Series: Filaggrin in Atopic Dermatitis, Journal of Allergy ...
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32 Gene find may bring better eczema help, say scientists | Science
https://www.theguardian.com/science/2007/apr/09/genetics.medicineandhealth
Genetic tests to identify children at risk of eczema and asthma and improve ... but other populations worldwide," said Irwin McLean at the ...
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33 Filaggrin in the frontline: role in skin barrier function and disease
https://journals.biologists.com/jcs/article/122/9/1285/35613/Filaggrin-in-the-frontline-role-in-skin-barrier
W. H. Irwin McLean ... A defective skin barrier is a key feature of the chronic inflammatory skin disease atopic eczema and, in 2006, ...
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34 Chromosome 11q13.5 variant associated with childhood ...
https://cyberleninka.org/article/n/1181355
... Alan D. Irvine, W.H. Irwin McLean, et al. Background Atopic eczema is a common inflammatory skin disease with multifactorial etiology.
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35 Skin: Into the breach - Nature
https://www.nature.com/articles/479S12a
Irvine had been working with geneticist Irwin McLean at ... The orderly layers of healthy skin contrast with the eruptions of eczema.
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36 Medline ® Abstract for Reference 110 of 'Atopic dermatitis ...
https://www.uptodate.com/contents/atopic-dermatitis-eczema-pathogenesis-clinical-manifestations-and-diagnosis/abstract/110
AU: Brough HA, Liu AH, Sicherer S, Makinson K, Douiri A, Brown SJ, Stephens AC, Irwin McLean WH, Turcanu V, Wood RA, Jones SM, Burks W, Dawson P, ...
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37 Null Mutations in the Filaggrin Gene (FLG ... - Labordoc
https://labordoc.ilo.org/discovery/fulldisplay/cdi_elsevier_sciencedirect_doi_10_1038_sj_jid_5700587/41ILO_INST:41ILO_V1
Atopic dermatitis (AD) is a common disease with a complex etiology in childhood and ... Reynolds, Nicholas J. ; Trembath, Richard C. ; Irwin McLean, W.H. ;.
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38 Emollient enhancement of the skin barrier from birth offers ...
https://ohsu.pure.elsevier.com/en/publications/emollient-enhancement-of-the-skin-barrier-from-birth-offers-effec-2
... barrier from birth offers effective atopic dermatitis prevention ... Kim S. Thomas, Michael J. Cork, W. H.Irwin McLean, Sara J. Brown, ...
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39 Filaggrin loss-of-function mutations and atopic dermatitis as risk ...
https://researchinformation.amsterdamumc.org/en/publications/c1415c4a-59c4-45d0-b1a4-4edd3e9d6e4f
Maaike J. Visser, Maarten M. Verberk, Linda E. Campbell, W. H. Irwin McLean, Florentine Calkoen, Jan G. Bakker, Frank J. H. van Dijk, Jan D. Bos, ...
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40 Filaggrin Plays Critical Role in Skin Barrier Health - MDedge
https://www.mdedge.com/dermatology/article/7171/atopic-dermatitis/filaggrin-plays-critical-role-skin-barrier-health
... for allergic rhinitis and eczema-related asthma, the results of two. ... W.H. Irwin McLean, Ph.D., noted in his René Touraine Lecture at ...
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41 About: Irwin McLean - DBpedia
https://dbpedia.org/page/Irwin_McLean
(William Henry) Irwin McLean (born 1963) FRS FRSE FMedSci is Emeritus ... Dermatology (en); Drug discovery (en); Keratins (en); (en); Atopic eczema (en) ...
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42 Null Mutations in the Filaggrin Gene ... - Tufts JumboSearch
https://tufts.primo.exlibrisgroup.com/discovery/fulldisplay?docid=cdi_proquest_miscellaneous_904481506&context=PC&vid=01TUN_INST:01TUN&lang=en&search_scope=MyInst_and_CI&adaptor=Primo%20Central&tab=Everything&query=null%2C%2CLondon%20%3B%20New%20York%20%3A%20Springer%2CAND&mode=advanced&offset=0
Atopic dermatitis (AD) is a common disease with a complex etiology in childhood and ... Reynolds, Nicholas J. ; Trembath, Richard C. ; Irwin McLean, W.H..
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43 DEBRA UK - Congratulations to Prof. Irwin McLean who has...
https://www.facebook.com/DEBRACharity/posts/congratulations-to-prof-irwin-mclean-who-has-been-awarded-the-prestigious-buchan/10153522617533478/
Irwin McLean is Professor of Human Genetics and Scientific Director of the Centre for Dermatology and Genetic Medicine @DundeeUniversity and he ...
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44 Atopic Dermatitis | Clinical Genomics - AccessMedicine
https://accessmedicine.mhmedical.com/content.aspx?bookid=1094§ionid=61905115
AMA Citation Brown SJ, McLean W. Brown S.J., & McLean W Brown, Sara J., and W. H. Irwin McLean.Atopic Dermatitis. In: Murray MF, Babyatsky MW, Giovanni MA, ...
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45 Ichthyosis vulgaris research update
https://www.ichthyosis.org.uk/ichthyosis-vulgaris-research-update
The research group in Dundee, Scotland, led by Professor Irwin McLean first ... Not all eczema cases have filaggrin gene mutations, but eczema caused by ...
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46 Dry Skin and the Filaggrin Gene
https://www.eczema.org.nz/dry-skin-and-the-filaggrin-gene/
Dry skin and atopic eczema: an update on the filaggrin story… what does it ... since the groundbreaking publication from Professor Irwin McLean's group, ...
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47 New Genetic Mutation Helps Explain Development of Eczema ...
https://www.technologynetworks.com/tn/news/new-genetic-mutation-helps-explain-development-of-eczema-202620
Professor Irwin McLean, Scientific Director of the Centre for Dermatology and Genetic Medicine at the University of Dundee, jointly led the research that ...
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48 Professor Irwin McLean - Royal Society of Edinburgh
https://rse.org.uk/fellowship/professor-irwin-mclean/
Irwin McLean FRS FRSE FMedSci FRSB FRSA is a retired biomedical scientist. ... the importance of skin barrier function in preventing atopic eczema and paved ...
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49 Filaggrin - the major predisposing gene for atopic disease and ...
https://impact.ref.ac.uk/CaseStudies/CaseStudy.aspx?Id=35837
Atopic eczema and associated conditions — asthma, food allergy and hay ... when the group of Prof Irwin McLean (Professor of Human Genetics and Head of the ...
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50 Body News: Skin Genes - Allure
https://www.allure.com/story/skin-genes
Now scientists have discovered eczema's primary cause: a faulty gene. ... 70 percent also develop eczema, according to Irwin McLean of the ...
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51 REF Impact Case Studies
https://ref2014impact.azurewebsites.net/casestudies2/refservice.svc/GetCaseStudyPDF/35837
Atopic eczema and associated conditions – asthma, food allergy and hay fever ... 2006, when the group of Prof Irwin McLean (Professor of Human Genetics and ...
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52 Scientists Identify Gene Linked to Eczema | Skin Inc.
https://www.skininc.com/science/physiology/news/21889447/scientists-identify-gene-linked-to-eczema
"It was a really tough project, but because we had experience in this type of gene, we managed to crack it where others had failed," Professor Irwin McLean ...
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53 Eczema genetics: current state of knowledge and future goals.
https://www.semanticscholar.org/paper/Eczema-genetics%3A-current-state-of-knowledge-and-Brown-McLean/b536c2541e3e61941740ce7b499586acefe321e7
S. Brown, W. McLean; Published 1 March 2009; Biology · W. McLean; Published 1 March 2009 · Published 1 March 2009; Biology · The Journal of investigative ...
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54 Filaggrin loss-of-function mutations are associated with early onset ...
https://kclpure.kcl.ac.uk/portal/en/publications/filaggrin-lossoffunction-mutations-are-associated-with-early-onset-eczema-eczema-severity-and-transepidermal-water-loss-at-three-months-of-age(d3a83c26-23d0-4de5-b214-6456e69bf546).html
Carsten Flohr, Kirsty England, Suzana Radulovic, W. H. Irwin McLean, Linda E. Campbell, Jonathan Barker, Michael Perkin, Gideon Lack.
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55 Atopic dermatitis patients with filaggrin loss-of ... - CORE
https://core.ac.uk/download/77006235.pdf
Citation for published version (APA):. Roekevisch, E., Leeflang, M. M. G., Schram, M. E., Campbell, L. E., Irwin McLean, W. H., Kezic, S., .
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56 Eczema Symptoms - Latest evidence on supplements, diets ...
https://examine.com/outcomes/eczema-symptoms/
The latest research on Eczema Symptoms Outcomes. ... Alan D Irvine, W H Irwin McLean, Donald Y M LeungFilaggrin mutations associated with skin and allergic ...
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57 Person: Irwin McLean - Irish Examiner
https://www.irishexaminer.com/maintopics/person-irwin-mclean_topic-272258.html
Person: Irwin McLean. ... Irish doctors identify genetic mutation that causes eczema. A study led by two Irish doctors has identified the genetic mutation ...
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58 Eczema gene identified in study led by Irish doctors
https://www.irishtimes.com/news/eczema-gene-identified-in-study-led-by-irish-doctors-1.1030303
... Our Lady's Hospital for Sick Children in Crumlin, Dublin, and Prof Irwin McLean, a geneticist at the University of Dundee in Scotland.
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59 Filaggrin Mutations Associated with Skin and Allergic Diseases
https://www.nejm.org/doi/full/10.1056/nejmra1011040
Alan D. Irvine, M.D.,; W.H. Irwin McLean, Ph.D., D.Sc.,; and Donald Y.M. ... including atopic dermatitis (which affects 42% of all mutation ...
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60 Professor Sara Brown | The University of Edinburgh
https://www.ed.ac.uk/inflammation-research/people/principal-investigators/prof-sara-brown
... the laboratory of Professor Irwin McLean, a leader in the field of Epithelial Genetics and at the forefront of eczema genetic research, ...
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61 Gene discovery gives fresh hope for eczema sufferers
https://www.independent.ie/world-news/europe/gene-discovery-gives-fresh-hope-for-eczema-sufferers-26395097.html
The Dundee team, led by Professor Irwin McLean, found several strong links: * In families affected by ichthyosis vulgaris, a significant ...
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62 The Science of Atopic Dermatitis | LiVDerm
https://www.livderm.org/wp-content/uploads/2021/09/Atopic_Dermatitis_The_Science_of_Atopic_Dermatitis_Fernanda_Schmidt.pdf
Filaggrin. Adapted from Brown S, Irwin McLean WH ... Decreased cathelicidins → viral infections such as eczema herpeticum.
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63 Eczema-prone skin? You probably need to 'feed your filaggrin'
https://www.healthawareness.co.uk/dermatology/eczema-prone-skin-you-probably-need-to-feed-your-filaggrin/
Then a seminal study from a group led by Professor Irwin McLean2 in Dundee, demonstrated that genetic variants of the skin barrier protein, filaggrin, ...
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64 KUNA : New eczema treatments on horizon - 20/03/2006 - كونا
https://www.kuna.net.kw/ArticleDetails.aspx?id=1651925&language=en
Professor Irwin McLean, of Dundee University's human genetics department, said in a statement the elusive gene had been known for about 20 ...
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65 More Mutations Of Gene That Cause Skin Disorders And ...
https://www.medindia.net/news/view_news_main.asp?x=19859
Says Irwin McLean at the College of Medicine, Dentistry and Nursing ... If both genes are faulty, the problems lead to eczema, asthma, and, ...
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66 The Scientist : The Allergy... - Pachyonychia Congenita Project
https://www.pachyonychia.org/wp-content/uploads/2016/12/McLean-W.H.I.-2010f.pdf
By By W. H. Irwin McLean. The Scientist : The Allergy Gene ... for eczema,2 as well as for other common allergies. The hunt.
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67 Gene-environment interaction in the onset of eczema in infancy ...
https://doaj.org/article/85a5d00a24b9495d88ff77505d6db929
Hans Bisgaard,; Angela Simpson,; Colin N A Palmer,; Klaus Bønnelykke,; Irwin McLean,; Somnath Mukhopadhyay,; Christian B Pipper,; Liselotte B Halkjaer, ...
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68 Ten new Genetic Risk Loci for Eczema Discovered | MDC Berlin
https://www.mdc-berlin.de/news/archive/2015/20151020-ten_new_genetic_risk_loci_for_eczema_disco
Among the new candidate genes for eczema, the researchers came upon ... Gerard H Koppelman103, Deborah Jarvis104,105, W H Irwin McLean83, ...
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69 New study may help eczema sufferers - RTE
https://www.rte.ie/news/2006/0320/74255-eczema/
... Consultant Paediatric Dermatologist at Our Lady's Hospital for Sick Children in Crumlin, Dublin, and by Professor Irwin McLean, ...
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70 Press Release from the University of Dundee - Pfizer
https://cdn.pfizer.com/pfizercom/partnering/recent_partnership/Dundee_Pfizer_PressRelease_020515.pdf
program of research within the laboratory of Professor Irwin McLean, Head of Molecular ... bullosa (EB) and more common conditions such as eczema.
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71 Gene hope for eczema sufferers - The Times
https://www.thetimes.co.uk/article/gene-hope-for-eczema-sufferers-m767d6nldcb
THE gene that causes dry skin and predisposes people to eczema and asthma has ... led by Professor Irwin McLean, found several strong links:.
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72 Breakthrough in search for eczema cure - BelfastTelegraph.co.uk
https://m.belfasttelegraph.co.uk/business/news/breakthrough-in-search-for-eczema-cure-28481259.html
The team was led by Professor Irwin McLean who is originally from Ballymoney and is Professor of Human Genetics and Head of the Division of Molecular ...
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73 Molecular Mechanism of Atopic Dermatitis ... - Springer Link
https://link.springer.com/article/10.5487/TR.2018.34.1.007
Sandilands, A., Sutherland, C., Irvine, A.D. and Irwin McLean, W.H. (2009) Filaggrin in the frontline: role in skin barrier function and ...
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74 Friction from paper and cardboard causing occupational ...
https://ouci.dntb.gov.ua/en/works/loy1MK17/
... Mancuso, Occupational dermatitis in shoemakers, Contact Dermatitis, № 34, с. 17 https://doi.org/10.1111/j.1600-0536.1996.tb02105.x; Irwin McLean, ...
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75 An update on the genetics of atopic dermatitis
https://search.lib.buffalo.edu/discovery/fulldisplay?docid=cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2874322&context=PC&vid=01SUNY_BUF:everything&lang=en&search_scope=UBSUNY&adaptor=Primo%20Central&tab=EverythingUBSUNY&query=null%2C%2C86%20pages%20%3B%2028%20cm%2CAND&mode=advanced
A genetic basis for atopic dermatitis (AD) has long been recognized. ... W H Irwin Mclean Journal of cell science.2009, Vol. 122(9), p. 1285-94.
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76 Chromosome 11q13.5 variant associated with childhood ...
https://www.lenus.ie/handle/10147/207388?show=full
Chromosome 11q13.5 variant associated with childhood eczema: an effect supplementary to filaggrin mutations. ... dc.contributor.author, McLean, W H Irwin.
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77 BBC NEWS | UK | Scotland | New eczema treatments on horizon
http://news.bbc.co.uk/2/hi/uk_news/scotland/tayside_and_central/4817512.stm
Professor Irwin McLean, of Dundee University's human genetics department, said the elusive gene had been known about for 20 years or more but ...
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78 Exome Sequencing and Rare Variant Analysis Reveals ...
https://oar.a-star.edu.sg/communities-collections/articles/14715
... in Bangladeshi Families with Atopic Eczema and Additional Risk Genes ... Hansjorg Baurecht, Stephan Weidinger, W. H. Irwin McLean, ...
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79 filaggrin loss-of-function mutations enhanced by neonatal cat ...
https://www.escholar.manchester.ac.uk/uk-ac-man-scw:246987
Gene-environment interaction in the onset of eczema in infancy: ... Bønnelykke, Klaus; McLean, Irwin; Mukhopadhyay, Somnath; Pipper, ...
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80 Molecular Mechanism of Atopic Dermatitis Induction Following ...
https://www.koreascience.or.kr/article/JAKO201809951100338.view?orgId=anpor&hide=breadcrumb,journalinfo
Molecular Mechanism of Atopic Dermatitis Induction Following Sensitization ... Brown, S.J. and Irwin McLean, W.H. (2012) One remarkable molecule: Filaggrin.
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81 Gene Discovery Gives Hope to Allergy Sufferers | Achoo! Blog
https://www.achooallergy.com/blog/filaggrin/
... response and appears to link asthma, hay fever, eczema, and peanu. ... Professor Irwin McLean, leader of the research team, explains, ...
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82 In vivo model systems to develop filaggrin as a drug target in ...
https://gtr.ukri.org/projects?ref=G0700314
We recently discovered that loss-of-function mutations in the filaggrin gene cause atopic dermatitis (eczema) and a host of other associated ...
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83 Avada Variants extracted from full text publications (R501X)
https://www.genome.ucsc.edu/cgi-bin/hgc?hgsid=1146697277_MXWmzZJmhfUFgz0PtthStOaIVj0s&db=hg19&c=chr1&l=152065557&r=152504439&o=152285860&t=152285861&g=avada&i=R501X
Title, Novel FLG null mutations in Korean patients with atopic dermatitis and comparison ... Authors, Irvine, Alan D; McLean, W H Irwin; Leung, Donald Y M.
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84 Getting under the skin of eczema
https://www.nationalchildrensresearchcentre.ie/our_impact/getting-skin-eczema/
Together with his colleague, Professor Irwin McLean (University of Dundee), he discovered the strongest genetic risk factor for eczema identified to date ...
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85 Loss-of-function variants in the filaggrin gene are a significant ...
https://research.rug.nl/en/publications/loss-of-function-variants-in-the-filaggrin-gene-are-a-significant
The association of filaggrin mutations with peanut allergy remains significant (P = .0008) after controlling for coexistent atopic dermatitis. Conclusion: ...
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86 Alan D. Irvine and W. H. Irwin McLean - Pobierz pdf z Docer.pl
https://docer.pl/doc/s00eexe
These results have greatly increased our understanding of the pathogenesis of atopic eczema, and they place filaggrin and, ultimately, skin ...
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87 Management of atopic eczema should be patient centred
https://www.guidelinesinpractice.co.uk/management-of-atopic-eczema-should-be-patient-centred/336027.article
Sandilands A, Sutherland C, Irvine A, Irwin McLean W. Filaggrin in the frontline: role in skin barrier function and disease.
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88 Molecular mechanisms in atopic eczema - why do they maZer in the ...
https://www.dspap.dk/wp-content/uploads/2020/04/DSPAP_Jan2017_SaraBrown_clinical-images-removed.pdf
Atopic eczema (& differenTal diagnoses). • Molecular mechanisms ... Atopic eczema (atopic dermaTTs) ... Irwin McLean. McLean lab. Department of. Dermatology.
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89 Eczema Producing Gene Discovered - RxPG News
http://www.rxpgnews.com/research/dermatology/article_3751.shtml
The first study, led by geneticists Professor Irwin McLean and Dr Frances Smith in Dundee and their dermatology colleague, Dr Alan Irvine, ...
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90 Eczema - McLean Dermatology & Skincare Center
https://www.mcleanskin.com/concerns/eczema/
Eczema. Over the years, McLean Dermatology providers have worked with many patients who were struggling with eczema (also known as dermatitis).
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91 Join the wait list for our breakthrough new body balm – Nursem ...
https://www.nursem.co.uk/pages/dry-skin-gene-join-wait-list
So we created our Ultra Caring body balm, an intensive formula designed specifically for those with dry, sensitive and eczema prone skin. Sign up to be the ...
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92 General 1 — irwinmclean.com
https://www.irwinmclean.com/science
Filaggrin is important in atopic dermatitis (eczema), allergy and allergic asthma. ... Irwin McLean BSc (Hons) PhD DSc FRS FRSE FMedSci MAE FRSB FRSA.
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93 Treatment of Dry Skin Syndrome: The Art and Science of ...
https://books.google.com/books?id=7oqH5_u-Xo0C&pg=PA55&lpg=PA55&dq=irwin+mclean+eczema&source=bl&ots=10AkWgQ-_3&sig=ACfU3U3EFsaSYidVYV2_VkDfMP0T6hqvpw&hl=en&sa=X&ved=2ahUKEwi8joj4zNj7AhXZGVkFHaW7AiQQ6AF6BQi1AhAD
... Sandilands A, McLean WH, Irvine AD (2008) Filaggrin in atopic dermatitis. ... Campbell Linda E, Cordell Heather J, Irvine Alan D, Irwin McLean WH, ...
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94 Skin Barrier Function - Page 45 - Google Books Result
https://books.google.com/books?id=n2ueCwAAQBAJ&pg=PA45&lpg=PA45&dq=irwin+mclean+eczema&source=bl&ots=-jTZyQFm10&sig=ACfU3U1Aiqmx4TWND-Q8hYA-UcWuKqzlyA&hl=en&sa=X&ved=2ahUKEwi8joj4zNj7AhXZGVkFHaW7AiQQ6AF6BQi0AhAD
... Verberk MM: Individual susceptibility to occupational contact dermatitis. Ind Health 2009;47: 469–478. Visser MJ, Verberk MM, Campbell LE, Irwin McLean ...
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95 Food Allergy: Molecular Basis and Clinical Practice
https://books.google.com/books?id=pFzMCQAAQBAJ&pg=PA47&lpg=PA47&dq=irwin+mclean+eczema&source=bl&ots=s1b9YHu0b5&sig=ACfU3U1F0H_R0tyQYELQrQfF3sQapV7HDw&hl=en&sa=X&ved=2ahUKEwi8joj4zNj7AhXZGVkFHaW7AiQQ6AF6BQi2AhAD
... diseases – per-'eczema'tous sensitiza- tion drives the allergy march. ... Campbell LE, Maccallum SF, Irwin McLean WH, Lack G: Atopic dermatitis and ...
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