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1 Management of skin rash during egfr-targeted ... - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644628/
According to our experience, we developed a therapeutic protocol that recommends the application once or twice a day (depending on the severity of the rash) of ...
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2 Epidermal Growth Factor Receptor Inhibitors and Skin Rash
https://www.uspharmacist.com/article/epidermal-growth-factor-receptor-inhibitors-and-skin-rash
For moderate and severe rashes, the topical treatments used for mild rash plus doxycycline or minocycline are recommended. Severe rash that is ...
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3 Prevention and Treatment of Acneiform Rash in Patients ...
https://www.albertahealthservices.ca/assets/info/hp/cancer/if-hp-cancer-guide-supp003-egfri-rash.pdf
See Table 3 for a summary of key evidence. However, we cannot conclude from these studies that EGFR inhibitor therapy is ineffective if no or only mild rash ...
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4 Treating Skin-Associated Toxicities Related to EGFR Inhibitors
https://www.cancernetwork.com/view/treating-skin-associated-toxicities-related-egfr-inhibitors
It is recommended that patients treated with EGFR inhibitors begin prophylactic rash therapy with doxycycline 100 mg twice a day or minocycline ...
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5 Acneiform eruption secondary to epidermal ... - UpToDate
https://www.uptodate.com/contents/acneiform-eruption-secondary-to-epidermal-growth-factor-receptor-egfr-and-mek-inhibitors
Acneiform eruption is the prototypical cutaneous adverse reaction associated with all epidermal growth factor receptor (EGFR) inhibitors, ...
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6 Acneiform Rash Induced by EGFR Inhibitors - Karger Publishers
https://www.karger.com/Article/Fulltext/371821
Acneiform rash is the most common side effect of epidermal growth factor receptor (EGFR) inhibitors (EGFRis), and it occurs in 50-100% of ...
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7 Reducing Acneiform Rash Induced by EGFR Inhibitors With ...
https://www.frontiersin.org/articles/10.3389/fphar.2022.835166/full
Acneiform rashes usually develop in the first 1–2 weeks after EGFRI therapy. In this study, we found that prophylactic treatment with ...
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8 Prevention and management of acneiform rash associated ...
https://onlinelibrary.wiley.com/doi/full/10.1111/ajco.13740
Epidermal growth factor receptor (EGFR) inhibitors are established therapies for advanced lung, colorectal, and head and neck cancers. They ...
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9 Management Strategies for Cutaneous Toxicity From EGFR ...
https://voice.ons.org/news-and-views/management-strategies-for-cutaneous-toxicity-from-egfr-inhibitors
Skin rash's typical presentation is often described as acne or an acneiform rash with onset typically occurring within the first two weeks of ...
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10 1241-Acneiform rash associated with EGFR inhibitors - eviQ
https://www.eviq.org.au/clinical-resources/side-effect-and-toxicity-management/hair-skin-and-nails/1241-acneiform-rash-associated-with-egfr-inhibitor
Treatment (of established disease) · moisturise the skin with an alcohol-free thick moisturising/emollient cream at least twice a day · avoid sun exposure as rash ...
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11 Prophylactic Treatment of Skin Rash Associated With EGFR ...
https://clinicaltrials.gov/ct2/show/NCT04239846
Prophylactic Treatment of Skin Rash Associated With EGFR Inhibitor Therapy · Is between 20 and 80 years of age, inclusive. · Patients who are within ±3 days of ...
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12 EGFR Inhibitor-induced Acneiform Rash: A Review of Current ...
https://practicaldermatology.com/articles/2013-aug/egfr-inhibitor-induced-acneiform-rash-a-review-of-current-management-strategies
Patients may benefit from medium- to high-potency topical corticosteroids such as alclometasone 0.05% cream daily or fluocinonide 0.05% cream twice daily for ...
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13 Management and grading of EGFR inhibitor-induced ...
https://www.futuremedicine.com/doi/10.2217/fon-2018-0187
by J Beech · 2018 · Cited by 34 —
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14 What is the role of topical creams, skin moisturisers and ...
https://wiki.cancer.org.au/australia/Clinical_question:What_is_the_role_of_topical_creams,_skin_moisturisers_and_maintenance_antibiotics_in_the_treatment_of_rash_from_anti-EGFR_therapy_in_patients_with_lung_cancer%3F
The positive association of rash with treatment responses vexes this issue. Where tumour progression has occurred on treatment the EGFR ...
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15 Clinical signs, pathophysiology and management of skin ...
https://www.sciencedirect.com/science/article/pii/S0923753419549869
A considerable number of patients treated with these EGFR inhibitors, however, develop dermatological side-effects, most frequently an acneiform eruption but ...
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16 Skin Toxicity Evaluation Protocol With Panitumumab (STEPP ...
https://ascopubs.org/doi/10.1200/jco.2008.21.7828
Patients receiving panitumumab-containing therapy were randomly assigned 1:1 to pre-emptive or reactive treatment (after skin toxicity ...
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17 EGFR Inhibitors and Cutaneous Complications - Springer Link
https://link.springer.com/article/10.1007/s40487-017-0050-6
The most common dermatologic adverse events caused by EGFR inhibitors include characteristic papulopustular eruptions, dry and itchy skin, hair ...
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18 A review of the treatment options for skin rash induced by ...
https://www.scienceopen.com/document_file/2ad555e7-6721-408d-88b0-2df8d227c7da/PubMedCentral/2ad555e7-6721-408d-88b0-2df8d227c7da.pdf
Background. Agents targeting the epidermal growth factor receptor (EGFR) are amongst the most extensively used of the targeted agents in the therapy of some ...
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19 Managing EGFR Inhibitor Associated Skin Toxicity - OncLive
https://www.onclive.com/view/managing-egfr-inhibitor-associated-skin-toxicity
Strategies are currently being developed, for the management of acneiform rash to EGFR inhibitors, explains Lacouture. A trial using topical ...
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20 Skin Care During Treatment With Epidermal Growth Factor ...
https://www.mskcc.org/cancer-care/patient-education/skin-care-during-treatment-targeted-therapies
EGFRi are a type of cancer treatments called targeted therapies. Targeted therapies can cause different side effects than normal chemotherapy ...
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21 Chemo Rash & EGFR Rash Treatment - Lindi Skin
https://lindiskin.com/pages/egfr-face-rash
Chemo Rash, which is also known as EGFR Rash, is a common skin-related side effect of certain chemotherapy medications. The dry skin rash is typically ...
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22 Management of EGFR-inhibitor associated rash
https://eurjmedres.biomedcentral.com/articles/10.1186/2047-783X-17-4
Within the first days to weeks of therapy > 90% of patients develop these rashes. In the majority of cases skin lesions initially appear within ...
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23 EGFR Inhibitor–Associated Papulopustular Rash
https://jhoponline.com/jhop-issue-archive/2017-issues/jhop-march-2017-vol-7-no-1/17060-egfr-inhibitor-associated-papulopustular-rash
Papulopustular rash is the most common dermatologic adverse event that may occur with EGFR inhibitors, with an incidence of up to 90%. ... This adverse event may ...
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24 Oncology TV > Symptom Management > Cutaneous Toxicities
https://www.oncology.tv/SymptomManagement/CutaneousToxicities
Other Cutaneous Toxicities · Xerosis (abnormally dry skin) is a common side effect of HER1/EGFR-targeted therapy · Painful fissures may develop on the fingers and ...
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25 Interdisciplinary management of EGFR-inhibitor-induced skin ...
https://www.annalsofoncology.org/article/S0923-7534(19)38597-7/fulltext
It was concluded that EGFR-inhibitor-related dermatologic reactions should always be treated combining basic care of the skin and a specific therapy adapted to ...
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26 SKIN TOXICITY Tips for Managing Side Effects of the Skin
https://fightcolorectalcancer.org/wp-content/uploads/2019/11/SkinToxicity_MiniMag_2019_WEB.pdf
We FIGHT to cure colorectal cancer ... treated with an EGFR-inhibitor will ... Skin rash is different for everyone, and dermatologists often categorize.
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27 The challenge of managing a cetuximab rash - MDedge
https://www.mdedge.com/hematology-oncology/article/190465/patient-survivor-care/challenge-managing-cetuximab-rash
They recommended vitamin K1 (menadione) cream, topical antibiotics, topical intermediate potency steroids, and oral antibiotic therapy for up to 4 weeks for ...
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28 Combined Treatment of Acneiform Rash Involved in ...
https://www.emjreviews.com/dermatology/abstract/combined-treatment-of-acneiform-rash-involved-in-epidermal-growth-factor-receptor-inhibitors-therapy/
Treatment with oral doxycycline at the early stages of Grade I-II acneiform rash led to significant clinical impact by preventing further dermatological ...
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29 Correlation between Development of Rash and Efficacy in ...
https://aacrjournals.org/clincancerres/article/13/13/3913/193366/Correlation-between-Development-of-Rash-and
Patients treated with epidermal growth factor receptor (EGFR) inhibitors frequently develop a rash characterized by inflammatory papules and ...
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30 A review of cutaneous toxicities from targeted therapies in the ...
https://jgo.amegroups.com/article/view/1285/html
They presented a treatment algorithm to help manage these patients. Upon initiation of treatment with the EGFR inhibitor they started patients on daily ...
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31 Management of Skin Rash during egfr-Targeted Monoclonal ...
https://www.mdpi.com/1718-7729/16/1/361
This reversible condition requires intervention in approximately one third of patients. A proactive, multidisciplinary approach to management can help to ...
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32 Prophylactic Dermatologic Treatment of Afatinib-Induced Skin ...
https://www.hindawi.com/journals/scientifica/2019/9136249/
Background. Severe skin rash is listed among important side effects of EGFR tyrosine kinase inhibitors. Polydatin (PD), a glycosylated polyphenol, is endowed ...
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33 EGFR Treatment for mCRC & SCCHN | ERBITUX (cetuximab)
https://www.erbitux.com/treatment
Learn about ERBITUX, an EGFR inhibitor for metastatic colorectal cancer and head and neck cancer. ... Acne-like skin rash during EGFR treatment may:.
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34 Clinical Guideline for the Management of Skin Toxicity ...
https://www.nhsscotlandnorth.scot/uploads/tinymce/NCA/SACT%20Guidelines/NOS-STG-006_Skin%20toxicity_version%201.pdf
Note scale different for EGFR inhibitors - please see Table 4. This table describes the grading and management of skin rash. Drug rashes are usually mild,.
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35 Skin Reactions to Targeted Therapy and Immunotherapy
https://www.cancer.net/coping-with-cancer/physical-emotional-and-social-effects-cancer/managing-physical-side-effects/skin-reactions-targeted-therapy-and-immunotherapy
This means rashes and changes to the hair and nails may occur during treatment with these drugs. Most people taking drugs that target EGFR ...
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36 The Cost and Value of Anti–Epidermal Growth Factor ...
https://jamanetwork.com/journals/jamaoncology/fullarticle/2203831
(A similar problem exists with the even smaller, much smaller, randomized phase 2 PEAK trial). ... The skin rash from anti-EGFR therapy is often a ...
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37 Relationship between skin rash and outcome in non-small-cell ...
https://www.lungcancerjournal.info/article/S0169-5002(12)00390-X/abstract
These results are noteworthy, because patients with severe skin rash may be reassured over treatment outcome Skin rash during treatment with anti-EGFR TKIs for ...
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38 Latest News : Side effect of cancer treatment can be safely ...
https://cancer.ucla.edu/Home/Components/News/News/1672
Topical therapy provides protection against skin rash caused by EGFR inhibitors ... UCLA cancer researchers (left to right) Drs. Antoni Ribas and ...
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39 Skin Rash could Predict the Response to EGFR Tyrosine ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055128
skin rash after EGFR-TKI treatment may be an efficient clinical marker for predicting the response of patients with NSCLC to EGFR-TKIs.
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40 Cutaneous Manifestations of EGFR-Inhibitors in African ...
https://jddonline.com/articles/cutaneous-manifestations-of-egfr-inhibitors-in-african-americans-and-treatment-considerations-S1545961620P0894X
However, treatment options for EGFR-inhibitor induced rash may not be generalizable to African Americans whose differences in skin biology and sensitivity ...
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41 Top 6: Need to Know About EGFR Inhibitors Rash Management
https://www.ccalliance.org/blog/patient-support/top-6-need-to-know-about-egfr-inhibitors-rash-management
Preventing side effects is essential, particularly drying of the skin. · Limit sun exposure by wearing long-sleeved shirts and pants, as well as ...
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42 Skin problems and EGFR-tyrosine kinase inhibitor
https://academic.oup.com/jjco/article/46/4/291/2384961
Generally, topical steroid cream or ointment is prescribed for the treatment of EGFR inhibitor-associated skin rash, especially for acneiform ...
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43 Associations between skin rash, treatment outcome, and ...
https://www.tandfonline.com/doi/full/10.1080/0284186X.2018.1464664
Nine SNPs in the candidate genes EGFR, EGF, AREG, FCGR2A, FCGR3A, and CCND1 were successfully determined in 294 patients. Clinical endpoints were moderate to ...
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44 Dermatologic Toxicity Occurring During Anti-EGFR ...
https://www.clinical-colorectal-cancer.com/article/S1533-0028(16)30278-X/pdf
with these anti-EGFR antibodies.21,22. Treatment with anti-EGFR agents has been associated with a number of dermatologic toxicities (including skin rash, ...
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45 Reactive Management for Acneiform Rash Grade 1-3
https://oncologypro.esmo.org/oncology-in-practice/palliative-and-supportive-care/egfri-related-skin-toxicity/healthcare-professionals/prophylaxis-and-treatment/reactive-management/acneiform-rash-grade-1-3
Topical antibiotics, such as metronidazole cream, clindamycin or erythromycin, used twice-daily or as needed. ... Metronidazole is preferred (as a 2% preparation ...
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46 Managing Side Effects of Vectibix
https://www.vectibix.com/safety-and-side-effects
Avoid the sun when possible, and wear a hat and sunscreen when you are out in the sun ; Skin Care. Use mild lotions or creams ; OTC topical treatments. Apply over ...
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47 EGFR Inhibitors Rash Management: Prevention Is Key
https://www.youtube.com/watch?v=IbsCL4vRQA4
Colorectal Cancer Alliance
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48 Clinical Management of Cutaneous Toxicity of Anti-EGFR ...
https://journals.sagepub.com/doi/pdf/10.1177/17246008070221s407
Relationship between rash and clinical effect. Skin reactions are considered a significant marker of in vivo EGFR targeting. A cutaneous rash may be taken.
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49 SYMPTOM MANAGEMENT GUIDELINES: ACNEIFORM RASH
http://www.bccancer.bc.ca/nursing-site/Documents/1.%20Acneiform%20Rash.pdf
any patient's care or treatment. ... Rash (acneiform rash on face, scalp or chest): erythema, edema, ... gloves if handling non-intact skin.
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50 Managing EGFR Skin Rash - Oral Chemotherapy Education
https://www.oralchemoedsheets.com/index.php/supplement-library/27-supplemental-available/496-egfrskinrash
A common side effect of EGFR cancer treatment is an acne-like skin rash that can occur mostly on the face, chest, back, arms, and scalp.
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51 Side effect of cancer treatment can be safely reduced with ...
https://www.uclahealth.org/news/side-effect-of-cancer-treatment-can-be-safely-reduced-with-topical-cream
Topical therapy provides protection against skin rash caused by EGFR ... For the past decade, epidermal growth factor receptor (EGFR) ...
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52 Predictive blood plasma biomarkers for EGFR inhibitor ...
https://www.oncotarget.com/article/17060/text/
The rash usually reaches its maximal manifestation two to three weeks after initiation of therapy [10]. Common recommendations for management of ...
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53 Doxycycline for Prevention of Erlotinib-Induced Rash in ...
https://www.practiceupdate.com/content/doxycycline-for-prevention-of-erlotinib-induced-rash-in-patients-with-non-small-cell-lung-cancer-after-failure-of-first-line-chemotherapy/37835
In practice, EGFR inhibitor–induced rash, once it develops, can be treated effectively with oral antibiotics, most commonly doxycycline or ...
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54 Skin Rash Can Be a Useful Marker for Afatinib Efficacy
https://ar.iiarjournals.org/content/38/3/1783
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are standard treatment for patients with EGFR mutation-positive advanced non-small- ...
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55 Increased FDG Uptake in Skin Rashes Caused by EGFR ...
https://journals.lww.com/nuclearmed/Fulltext/9900/Increased_FDG_Uptake_in_Skin_Rashes_Caused_by_EGFR.345.aspx
Most patients treated with epidermal growth factor receptor inhibitors develop cutaneous advance effects. The extent and severity of ...
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56 Definition of acneiform rash - NCI Dictionary of Cancer Terms
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/acneiform-rash
Sometimes, the affected skin becomes infected. Acneiform rash may be caused by an infection or by treatment with certain drugs, including some anticancer ...
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57 Tips for Managing Treatment-Related Rash and Dry Skin
https://media.cancercare.org/publications/original/8-ccc_rash.pdf
of people with colorectal cancer who were treated with cetuximab, an EGFR inhibitor. This clinical trial showed a strong link between the development of a rash ...
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58 Managing Side Effects From EGFR Inhibitors - CancerConnect
https://news.cancerconnect.com/treatment-care/managing-side-effects-from-egfr-inhibitors
Since the rash tends to be drying, applying a thick, emollient cream to the face and body once or twice a day as soon as the medication is started can be ...
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59 Predictors of Tumor Response to Cetuximab and ...
https://www.actasdermo.org/es-predictors-tumor-response-cetuximab-panitumumab-articulo-S1578219015001547
In total, 81.9% of the patients developed a papulopustular rash. Patients who received the most cycles of treatment with the EGFR inhibitor were at the highest ...
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60 [PDF] Management of skin rash during egfr-targeted ...
https://www.semanticscholar.org/paper/Management-of-skin-rash-during-egfr-targeted-for-Melosky-Burkes/b78dd7b50d61e76b66f6b088c8f0bbb65599321a
The present article focuses on egfr-targeted mAbs for the treatment of gi malignancy, addressing the pathophysiology, clinical presentation, ...
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61 Erlotinib-Induced Skin Rash. Pathogenesis, Clinical ...
https://www.primescholars.com/articles/erlotinibinduced-skin-rash-pathogenesis-clinical-significance-and-management-in-pancreatic-cancer-patients-98183.html
Mouse models suggest that the rash is transient and disappears with prolonged treatment, perhaps as a result of EGFR receptor blockade. Mitra and Simcock [16] ...
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62 Dermatologic toxicity occurring during anti-EGFR monoclonal ...
https://digitalcommons.wustl.edu/cgi/viewcontent.cgi?article=8879&context=open_access_pubs
with these anti-EGFR antibodies.21,22. Treatment with anti-EGFR agents has been associated with a number of dermatologic toxicities (including skin rash, ...
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63 When treatment gets under your skin…
https://archive.cancerworld.net/wp-content/uploads/2017/07/3019_CW18_14_22_grandround.pdf
EGFR inhibitors represent a bright hope for modern cancer therapies. But treatment comes at a price – an acne-like rash and other skin problems that can ...
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64 Managing Dermatologic Toxicities Associated With Targeted ...
https://www.oncnursingnews.com/view/managing-dermatologic-toxicities-associated-with-targeted-therapies
Prophylactic treatment of EGFR-associated rash involves the use of skin moisturizer creams and ointments, avoidance of excessive sun ...
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65 Panitumumab (Vectibix®) | OncoLink
https://www.oncolink.org/cancer-treatment/oncolink-rx/panitumumab-vectibix-r
Nail and Skin Changes · Use a thick, alcohol-free emollient lotion or cream on your skin at least twice a day, including right after bathing. · Avoid sun exposure ...
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66 Skin Toxicity in Cancer Treatment: A Critical Part of Cancer ...
https://www.targetedonc.com/view/skin-toxicity-in-cancer-treatment-a-critical-part-of-cancer-supportive-care
Additionally, patients with non-small cell lung cancer treated with an EGFR inhibitor and developing skin rash show better progression-free and ...
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67 Erlotinib-Induced Skin Rashes May Predict Better Outcomes
https://www.medscape.com/viewarticle/559355
Patients treated with EGFR inhibitors frequently develop skin rashes, which often look like acne and are typically characterized by ...
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68 Prophylactic antibiotics cut risk of anti-EGFR skin rash
https://medicalxpress.com/news/2016-06-prophylactic-antibiotics-anti-egfr-skin-rash.html
(HealthDay)—For patients receiving anti-epidermal growth factor receptor (EGFR) treatment, the risk of developing skin rash is reduced for ...
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69 A Rash of Good News - Cure Today
https://www.curetoday.com/view/a-rash-of-good-news
Although a rash isn't usually a welcomed sight, patients being treated with drugs that target the epidermal growth factor receptor, or EGFR, ...
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70 EGFR Inhibitors: Toxicities and Strategies - Medscape Education
https://www.medscape.org/viewarticle/579711_2
Pharmacologic Management of Rash. Treatment of EGFR inhibitor-induced rash is based on severity (Figure 2). Topical and oral antibiotics (minocycline, ...
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71 Severe acneiform eruption to EGFR inhibitor treated with ...
https://www.jaad.org/article/S0190-9622(17)31394-4/fulltext
› article › fulltext
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72 Prophylactic Antibiotics Cut Risk of Anti-EGFR Skin Rash - MPR
https://www.empr.com/home/news/prophylactic-antibiotics-cut-risk-of-anti-egfr-skin-rash/
HealthDay News — For patients receiving anti-epidermal growth factor receptor (EGFR) treatment, the risk of developing skin rash is reduced ...
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73 Quality of Life in Patients With Severe Skin Reactions
https://www.wjon.org/index.php/wjon/article/download/1381/1060
colorectal carcinoma; Metastases; Skin rash; Psychological reactions. Introduction ... mCRC treatment with EGFR expression and without RAS.
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74 Cetuximab-induced Acneiform Eruption and the Response to ...
https://www.medicaljournals.se/acta/content/html/10.2340/00015555-0330
Grade 2 rash should also be treated with topical antibiotic preparations. Systemic antibiotics, notably oral doxycycline, may be added mainly for anti- ...
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75 Gefitinib and Dermal Reaction: Uncovering the Path of ...
https://austinpublishinggroup.com/clinical-case-reports/fulltext/ajccr-v1-id1024.php
Here, we explored different treatment possibilities for the management of ... They presented with a 1 month history of skin rash rapidly progressing to ...
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76 Isotretinoin Plus Clindamycin Seem Highly Effective Against ...
https://www.jto.org/article/S1556-0864(15)31816-5/fulltext
Erlotinib is useful in advanced non-small cell lung cancer although compliance and efficacy are diminished by skin rash in a high proportion of patients, ...
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77 Skin, Nail, and Hair Changes with EGFR Inhibitors
https://assets.ctfassets.net/4yx69hifndy8/7124.pdf/69d127f67069d368a2e20ee5a32d2817/7124.pdf
The rash should go away within 4 weeks after you stop the EGFR inhibitor. Your doctor may order an antibiotic to help prevent or treat your rash. Acne medicines ...
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78 Safety Evaluations of Topical Vitamin K1 for Epidermal Growth ...
https://www.sciforschenonline.org/journals/drug/article-data/JDRD158/JDRD158.pdf
experience skin rash, pruritus, tenderness and inflammation of hair ... p-EGFR than cetuximab-treated cells with or without VK1 (Figure.
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79 HER1/EGFR inhibitor-associated rash - VIVO
https://vivo.weill.cornell.edu/display/pubid15851793
Suggestions for patients include makeup to camouflage the rash and an emollient to prevent and alleviate skin dryness. The increasing use of ...
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80 Changes in sebum levels and the development of acneiform ...
https://www.dovepress.com/changes-in-sebum-levels-and-the-development-of-acneiform-rash-in-patie-peer-reviewed-fulltext-article-OTT
Patients who developed rash during treatment showed greater differences ... and acneiform rash, a typical skin toxicity of EGFR inhibitors, ...
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81 Cutaneous side effects of EGFR and protein kinase inhibitors
https://dermnetnz.org/topics/egfr-and-protein-kinase-inhibitors
Although effective in the treatment of many cancers, EGFR inhibitors often result in adverse reactions in the skin, which occur in at least half of treated ...
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82 Atypical skin reaction in a patient treated with gefitinib for ...
https://www.spandidos-publications.com/10.3892/etm.2015.2881
The second most frequent systemic adverse effect of EGFR inhibitors is diarrhea, whose development can be associated with skin rash (16). Other ...
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83 EGFR Targeting TKI-Related Skin Toxicities in a Patient with ...
https://mdpi-res.com/d_attachment/curroncol/curroncol-29-00205/article_deploy/curroncol-29-00205-v2.pdf?version=1649220229
Keywords: EGFR inhibitors; TKI; dark skin tone; lung cancer; skin toxicity. 1. Introduction. Challenges in detecting erythema and rash in ...
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84 Managing EGFR inhibitor side effects in lung cancer patients
https://www.oncologynurseadvisor.com/home/departments/ce-courses/managing-egfr-inhibitor-side-effects-in-lung-cancer-patients/2/
Since the rash tends to be drying, ask the patient to apply a thick, emollient cream to the face and body once or twice a day as soon as the ...
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85 Acneiform eruption secondary to epidermal growth ... - medilib
https://www.medilib.ir/uptodate/show/15764
Furthermore, diminished expression of claudin-1, a tight junction protein, is significantly reduced in lesional skin of EGFR inhibitor-treated patients, ...
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86 Management of cutaneous side effects of cetuximab therapy ...
https://www.onko-i.si/fileadmin/onko/datoteke/dokumenti/RadiolOncol_42_4_7.pdf
It has shown activities against multiple malignancies in clinical trials. EGFR-inhibi- tors often cause skin toxicity, most frequently acneiform eruption.
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87 (PDF) A review of the treatment options for skin rash induced ...
https://www.researchgate.net/publication/242017847_A_review_of_the_treatment_options_for_skin_rash_induced_by_EGFR-targeted_therapies_Evidence_from_randomized_clinical_trials_and_a_meta-analysis
Vitamin K cream was also identified as having a potential role in the management EGFR-targeted agent induced rash. This review and meta-analysis ...
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88 Epidermal Growth Factor Receptor (EGFR) Inhibitor-Induced ...
https://www.liebertpub.com/doi/10.1089/jpm.2010.0258
Surprisingly, most patients, with the exception of 2, appear to have manifested evidence of rash improvement—even when unproven or disproved ...
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89 KEYTRUDA® (pembrolizumab)
https://www.keytruda.com/
KEYTRUDA is a prescription medicine used to treat: a kind of skin cancer called melanoma. It may be used when your melanoma has spread or cannot be removed ...
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90 EGFR Rash - Image Recovery Centers
http://imagerecovery.com/glossary/egfr-rash
Is a common skin-related side effect of certain medications, targeted therapy and chemotherapy. The dry skin rash is characterized by mild scaling, pimples, ...
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91 10 Signs You May Have Kidney Disease
https://www.kidney.org/news/ekidney/august14/10_Signs_You_May_Have_Kidney_Disease
You have dry and itchy skin. Healthy kidneys do many important jobs. They remove wastes and extra fluid from your body, help make red blood ...
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92 Scabies: Pictures of Rash & Mites, Symptoms, Treatment
https://www.webmd.com/skin-problems-and-treatments/ss/slideshow-scabies-overview
See scabies skin rashes, symptoms (night itching), treatments, and home care in this WebMD slideshow. Pictures show the itch mite, ...
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93 Carcinomas: New Insights for the Healthcare Professional: ...
https://books.google.com/books?id=LyMQwRGZPpAC&pg=PT490&lpg=PT490&dq=egfr+skin+rash+treatment&source=bl&ots=M_hiUDEuY3&sig=ACfU3U0vlvx-mFObKjkmplKZDuh4tOE9rA&hl=en&sa=X&ved=2ahUKEwi154vU4Nj7AhXNElkFHXNVC0cQ6AF6BQjGAhAD
Main symptoms caused by the skin rash are itching, dryness, and secondary ... who develop skin rash as a result of anti-EGFR therapy tend to live longer.
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94 Practical Clinical Oncology - Page 17 - Google Books Result
https://books.google.com/books?id=C-tiPcfnFKgC&pg=PA17&lpg=PA17&dq=egfr+skin+rash+treatment&source=bl&ots=aEFF9GeclJ&sig=ACfU3U2spZ2vmCt4UdnbcrMuRLDnwm2MuA&hl=en&sa=X&ved=2ahUKEwi154vU4Nj7AhXNElkFHXNVC0cQ6AF6BQjKAhAD
The main toxicities of lapatinib are diarrhoea and skin rash. Management of the skin rash with anti-EGFR agents Drugs that target the EGFR, ...
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95 Chronic kidney disease - Symptoms - NHS
https://www.nhs.uk/conditions/kidney-disease/symptoms/
This stage of CKD is known as kidney failure, end-stage renal disease or established renal failure. It may eventually require treatment with dialysis or a ...
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96 Pembrolizumab - Wikipedia
https://en.wikipedia.org/wiki/Pembrolizumab
Pembrolizumab, sold under the brand name Keytruda, is a humanized antibody used in cancer ... decreased appetite, itchy skin (pruritus), diarrhea, nausea, rash, ...
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97 The New England Journal of Medicine: Research & Review ...
https://www.nejm.org/

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