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1 K/BxN Serum-Transfer Arthritis as a Model for Human ... - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889615/
The K/BxN serum-transfer arthritis (STA) model is a murine model in which the immunological mechanisms occurring in rheumatoid arthritis ...
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2 Serum Transfer Model of Arthritis R Signaling in the K/B × N γ ...
https://www.jimmunol.org/content/jimmunol/169/11/6604.full.pdf
This model is similar to human rheumatoid arthritis (RA)3 in that both are chronic symmetric joint diseases with pannus formation, and destructive bone and ...
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3 "The K/BxN Arthritis Model". In: Current Protocols in Immunology
https://cbdm.hms.harvard.edu/assets/Publications/2008pub/MonachCurrProImm.pdf
K/BxN transgenic mice have been useful for investigating the development of autoimmunity, and the serum transfer model has been particularly valuable in ...
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4 The K/BxN mouse: a model of human inflammatory arthritis
http://www.cell.com/trends/molecular-medicine/abstract/S1471-4914(03)00249-1
Interestingly, whereas K/BxN mice developed chronic arthritis, arthritis induced by transfer of antibody or serum from arthritic K/BxN mice was transient, often ...
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5 (PDF) K/BxN Serum-Transfer Arthritis as a Model for ...
https://www.researchgate.net/publication/303747095_KBxN_Serum-Transfer_Arthritis_as_a_Model_for_Human_Inflammatory_Arthritis
The K/BxN serum-transfer arthritis (STA) model is a murine model in which the immunological mechanisms occurring in rheumatoid arthritis ...
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6 K/BxN Serum Transfer Arthritis as a Model of ... - Springer Link
https://link.springer.com/protocol/10.1007/978-1-61779-561-9_19
K/BxN serum-treated arthritic mice display maximal inflammation on day 6 and resolution of clinical signs by day 18. Figure l shows that the ...
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7 Analgesic effects of soluble epoxide hydrolase inhibitor in K ...
https://www.anesth-pain-med.org/journal/view.php?number=63
The K/BxN serum transfer arthritis mouse model uses antibodies directed to the early, late, and post-inflammatory phases. Unlike the systemic ...
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8 Arthritis Critically Dependent on Innate Immune System ...
https://www.sciencedirect.com/science/article/pii/S1074761302002753
The K/BxN serum-transfer system is highly advantageous for studying the effector mechanisms that link the production of potentially pathogenic Igs and the overt ...
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9 Myeloid Deletion of SIRT1 Aggravates Serum Transfer ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087733
K/BxN serum transfer arthritis was induced in mSIRT1 KO mice and age-matched littermate loxP control mice. Arthritis severity was assessed by ...
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10 Interleukin 17-expressing Innate Synovial Cells Drive K/Bxn ...
https://immunenetwork.org/DOIx.php?id=10.4110/in.2016.16.6.366
In this study, we evaluated whether IL-17 is essential for the effector phase of inflammatory arthritis in the K/BxN serum transfer model.
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11 The Role of FcγR Signaling in the K/B × N Serum Transfer ...
https://journals.aai.org/jimmunol/article/169/11/6604/74559/The-Role-of-Fc-R-Signaling-in-the-K-B-N-Serum
In the K/BxN serum transfer model of arthritis, there is a clinically apparent acute phase, which is modulated by FcγRII and FcγRIII, ...
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12 A novel mouse model that develops spontaneous arthritis and ...
https://ard.bmj.com/content/72/1/89
6,–,8 The arthritis is transferrable to naïve mice through injection of serum containing anti-G6PI antibodies,9 with the resulting inflammatory arthritis in ...
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13 Denervation protects limbs from inflammatory arthritis via an ...
https://www.pnas.org/doi/pdf/10.1073/pnas.1410854111
It proved possible to model hemiplegia-induced protection from arthritis in the K/BxN serum-transfer system: Serum recipi-.
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14 NF-κB–inducing kinase controls lymphocyte and osteoclast ...
https://www.jci.org/articles/view/23763
The serum transfer arthritis model is initiated by preformed antibodies and required only intact neutrophil and complement systems in recipients ...
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15 K/BxN Serum Transfer Arthritis as a Model of Inflammatory ...
https://experiments.springernature.com/articles/10.1007/978-1-61779-561-9_19
Clinical and pathological signs following induction of K/BxN serum transfer arthritis. Characterization of mechanical hypersensitivity in mice subjected to K/ ...
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16 Characterization of the KRN Cell Transfer Model of ...
https://ajp.amjpathol.org/article/S0002-9440(10)60192-7/fulltext
The KRN cell transfer model replicates many features of chronic rheumatoid arthritis in humans in a synchronized manner and lends itself to manipulation of ...
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17 EBioMedicine - The Lancet
https://www.thelancet.com/article/S2352-3964(18)30498-5/pdf
Methods: Arthritis was induced in wild type and myeloid Sirt6 knockout (mS6KO) mice using collagen-induced and K/BxN serum transfer models.
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18 The KRN mouse model of inflammatory arthritis - CORE
https://core.ac.uk/download/pdf/159148025.pdf
robust induction of joint inflammation by serum transfer this new disease model has been and will be a valuable means to address the as-yet-unanswered key ...
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19 4.3. The K/BxN Serum Transfer Arthritis Model and the Experimental ...
https://bio-protocol.org/bio101/r9036335
Arthritis was induced by ip. injection of 300 μL arthritogenic serum on day 0 of the experiment. In prior studies this was confirmed as a dose capable of ...
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20 K/BxN Serum-Transfer Arthritis as a Model for Human Inflammatory ...
https://www.semanticscholar.org/paper/K%2FBxN-Serum-Transfer-Arthritis-as-a-Model-for-Human-Christensen-Haase/e669f21d4dc8a2a3990ac2abc195ea88ec949944
The K/BxN serum-transfer arthritis (STA) model is a murine model in which the immunological mechanisms occurring in rheumatoid arthritis (RA) and other ...
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21 Myeloid IPMK promotes the resolution of serum transfer ...
https://www.tandfonline.com/doi/full/10.1080/19768354.2021.1952305
Using myeloid cell-specific IPMK knockout (KO) mice, arthritis was induced via intraperitoneal K/BxN serum injection, after which disease ...
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22 Th17 in Animal Models of Rheumatoid Arthritis | HTML - MDPI
https://www.mdpi.com/2077-0383/6/7/73/htm
by M Hashimoto · 2017 · Cited by 50 —
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23 The neuropathic phenotype of the K/BxN transgenic mouse ...
https://www.nature.com/articles/s41598-020-72441-5
The adult K/BxN transgenic mouse develops spontaneous autoimmune arthritis with joint remodeling and profound bone loss.
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24 Reduced Locomotor Activity Correlates with Increased ...
https://www.scirp.org/journal/paperinformation.aspx?paperid=43158
The K/BxN serum transfer arthritis in mice shares many immunological and pathological features with human RA. Very few studies are available in mice that ...
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25 K/BxN Serum-Transfer Arthritis as a Model for Human ... - OUCI
https://ouci.dntb.gov.ua/en/works/4wGnvGJ4/
K/BxN Serum-Transfer Arthritis as a Model for Human Inflammatory Arthritis · List of references · Publications that cite this publication.
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26 Gene Expression data from synovium in mouse serum transfer ...
https://www.refine.bio/experiments/GSE71599/gene-expression-data-from-synovium-in-mouse-serum-transfer-arthritis-model-sta-model
To find regulated genes during peak inflammation of rheumatoid arthritis (RA), we have collected synovium from mouse Serum Transfer Arthtitis (STA) model at day ...
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27 Pharmacologic induction of heme oxygenase 1 reduces acute ...
https://www.cochin-poa.com/wp-content/uploads/2017/03/Article-17.pdf
In the K/BxN mouse serum transfer model, which mimics human inflammatory arthritis without lymphocyte influence, HO-1 was up-regulated by intraperitoneal ...
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28 Collagen Antibody Induced Arthritis (CAIA) in Mice - Chondrex
https://www.chondrex.com/documents/Mouse-CAIA.pdf
mouse model for rheumatoid arthritis (RA). ... rapid arthritis model using monoclonal antibodies (mAbs) against ... in Rats. Passive Transfer With Serum and.
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29 G-Protein Receptor Kinases (grKs) Play an Important ...
https://www.jacionline.org/article/S0091-6749(06)03403-8/fulltext
CONCLUSIONS: The grK system is an important regulatory pathway in the K/BxN serum transfer model of inflammatory arthritis, but differs between the grK ...
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30 Antiangiogenic Nanotherapy With Methotrexate ... - Medscape
https://www.medscape.com/viewarticle/730179_2
Synergistic effect of fumagillin nanoparticles and methotrexate in inflammatory arthritis. Arthritis was induced by K/BxN serum transfer on day 0.
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31 Roles of mast cells in rheumatoid arthritis
https://www.kjim.org/m/makeCookie.php?url=/m/journal/view.php?number=170259
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory ... In the K/BxN serum transfer RA model, c-Jun N-terminal kinase (JNK) 1 ...
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32 Mouse Models of Rheumatoid Arthritis for Studies on ...
https://www.karger.com/Article/FullText/508239
The serum from K/BxN mice contains anti-G6PI autoantibodies and, thus, can be transferred to a variety of mouse strains, including B- and T-cell ...
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33 Mouse Models of Rheumatoid Arthritis - SAGE Journals
https://journals.sagepub.com/doi/10.1177/0300985815588612
Conceptually similar to CAIA, K/BxN antibody transfer arthritis is another model that makes use of induction with arthritogenic antibodies; however, in this ...
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34 New Studies of Pathogenesis of Rheumatoid Arthritis with ...
https://www.hindawi.com/journals/ad/2021/7385106/
Fortunately, Collagen-Induced Arthritis (CIA) and Collagen Antibody-Induced Arthritis (CAIA) models have been widely used as animal models for studying the ...
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35 1 Pain pathogenesis in rheumatoid arthritis - arXiv
https://arxiv.org/pdf/1903.04987
Capsaicin-sensitive sensory nerves exert complex regulatory functions in the serum-transfer mouse model of autoimmune arthritis. Brain. Behav. Immun. 2015;45:50 ...
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36 Immune-Mediated Arthritis and the HPA Axis - Arbor Assays
https://www.arborassays.com/immune-mediated-arthritis-and-the-hpa-axis/
In the second model, serum from the arthritic K/BxN mice was transferred to normal mice resulting in the induction of arthritis.
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37 NF-κB-inducing kinase controls lymphocyte and osteoclast ...
https://digitalcommons.wustl.edu/cgi/viewcontent.cgi?article=2462&context=open_access_pubs
the role of NIK in murine models of inflammatory arthritis using Nik–/– mice. The serum transfer arthritis model is initiated by preformed antibodies and ...
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38 Adenovirus-mediated delivery of Sema3A alleviates ...
https://www.oncotarget.com/article/19915/text/
Keywords: Sema3A, rheumatoid arthritis, serum-transfer induced mouse model, macrophages. Received: May 18, 2017 Accepted: June 28, ...
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39 Mapping pathogenesis of arthritis through small animal models
https://academic.oup.com/rheumatology/article/51/11/1931/1774507
Models of RA · 23]. · 24]. · 23, · 25], and transient arthritis can be transferred by injecting naive mice with serum IgG from arthritic mice in a ...
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40 Toll-like Receptor 2 Controls Acute Immune Complex–Driven ...
https://www.uab.edu/medicine/rheumatology/images/XL_-_Abdollahi-Roodsaz_et_al_2013.pdf
Serum-transfer arthritis was induced in ... experimental models where T and B cell responses are ... antibody-induced K/BxN serum-transfer arthritis. More-.
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41 Deficiency in IL-1 Receptor Type 2 Aggravates K/BxN Serum ...
https://archive-ouverte.unige.ch/unige:110653
To define the functional role of endogenous IL-1R2 in the K/BxN serum transfer arthritis model and in IL-1β- or LPS-induced systemic ...
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42 The K/BxN mouse model of inflammatory arthritis: theory and ...
https://experts.arizona.edu/en/publications/the-kbxn-mouse-model-of-inflammatory-arthritis-theory-and-practic
Mice expressing the KRN T cell receptor transgene and the MHC class II molecule A(g7) (K/BxN mice) develop severe inflammatory arthritis, and serum from ...
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43 Disease severity in K/BxN serum transfer-induced arthritis is ...
https://d-nb.info/1099346371/34
K/BxN serum transfer-induced model [22,23]. The first study concluded to a pathogenic role of IL-33 based on reduced arthritis severity in ...
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44 A First in Class Therapeutic Nanoparticle for Specific ...
https://acrabstracts.org/abstract/a-first-in-class-therapeutic-nanoparticle-for-specific-targeting-of-anti-citrullinated-protein-antibody-ameliorates-serum-transfer-and-collagen-induced-arthritis/
Background/Purpose: Rheumatoid arthritis (RA) is an immune mediated ... effect was confirmed in the serum transfer arthritis model (N=10).
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45 The Effect of Human Placental Extract on Rheumatoid Arthritis ...
https://www.e-arm.org/journal/view.php?number=108
We used (i) KRN C57BL/6 TCR transgenic x NOD mice (KBx/N) serum transfer arthritis and (ii) collagen-induced arthritis (CIA) mice to ...
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46 IL-17-producing T cells can augment - jstor
https://www.jstor.org/stable/40536174
mouse model of inflammatory arthritis, T cells initiate disease by ... CD4+ KRN T Cells Augmented Serum-Transferred Arthritis. We set out.
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47 Myeloid skewing in murine autoimmune arthritis occurs in ...
https://ashpublications.org/blood/article/120/11/2203/30216/Myeloid-skewing-in-murine-autoimmune-arthritis
We induced transient arthritis in wild-type B6 mice using the serum transfer model and determined mRNA expression of several genes in KSL ...
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48 Synoviocyte-targeted therapy synergizes with TNF inhibition in ...
https://www.science.org/doi/10.1126/sciadv.aba4353
Rheumatoid arthritis (RA) is the most common systemic autoimmune disease and is ... arthritis in the K/BxN serum transfer–induced arthritis (STIA) model but ...
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49 NIH Public Access - Cleveland Shoulder Institute
https://clevelandshoulder.com/research-articles/mast-cells-contribute-to-autoimmune-inflammatory-arthritis-via-their-tryptase-heparin-complexes.pdf
B×N mouse serum-transfer arthritis model. While inflammation in this experimental arthritis model was not dependent on protease activated receptor-2, ...
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50 Inflammatory and Post-Inflammatory Nociception in a Model of ...
https://kclpure.kcl.ac.uk/portal/en/theses/inflammatory-and-postinflammatory-nociception-in-a-model-of-arthritis(04479d1b-e95f-427d-9f2d-e88bb7fd6bbf).html
Taken together, the findings of this thesis demonstrate that in the K/BxN serum transfer model of inflammatory arthritis, there are distinct ...
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51 Applicability and implementation of the collagen‑induced ...
https://www.spandidos-publications.com/10.3892/etm.2021.10371
Among these models, the collagen‑induced arthritis (CIA) mouse model is the first choice and the most widely used because it may be generated ...
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52 Characterization of the acute and persistent pain state pres...
https://journals.lww.com/pain/fulltext/2010/11000/characterization_of_the_acute_and_persistent_pain.23.aspx
We characterized the K/BxN serum transfer arthritis model as a model of joint inflammation-induced pain and examined pharmacologic responsiveness and spinal ...
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53 Advances in Immunology - Page 87 - Google Books Result
https://books.google.com/books?id=IGa1DwAAQBAJ&pg=PA87&lpg=PA87&dq=serum+transfer+arthritis+model&source=bl&ots=bjdFPj2-Cl&sig=ACfU3U21XNaGB0_d5O7VFYneEYbNpIn7-Q&hl=en&sa=X&ved=2ahUKEwjOsuPM49j7AhWwMlkFHRnxAaAQ6AF6BQj_ARAD
... of different mononuclear phagocyte subsets during mouse models of arthritis ... protected in the model of K/BxN serum transfer arthritis and even showed ...
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54 FTY720 inhibits development of collagen-induced arthritis
https://www.dovepress.com/fty720-inhibits-the-development-of-collagen-induced-arthritis-in-mice--peer-reviewed-fulltext-article-DDDT
The effects of FTY720 which is positive have been measured in a murine rheumatoid arthritis model. Researchers found that FTY720 could ...
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55 Definition of sudden infant death syndrome - NCI Dictionary of ...
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/sudden-infant-death-syndrome
› cancer-terms › def › sudden-i...
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56 Here's How Inflammation Affects Your Iron Levels
https://blog.insidetracker.com/how-inflammation-affects-your-iron-group
Another interesting scenario is a sharp drop in serum iron and TS with subsequent increases in WBC or hsCRP. Since a spike in hepcidin caused by ...
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57 Immunoglobulin G - Wikipedia
https://en.wikipedia.org/wiki/Immunoglobulin_G
Immunoglobulin G (Ig G) is a type of antibody. Representing approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found ...
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58 Walgreens: Pharmacy, Health & Wellness, Photo & More for You
https://www.walgreens.com/

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59 ACS Nano - ACS Publications - American Chemical Society
https://pubs.acs.org/journal/ancac3
Genetics (1417) · Rodent models (834) · Anatomy (736) · Membranes (714) · Bacteria (260) · Morphology (199) · Antigens (82) · Serum (65) · Hybridization (47) ...
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60 Login | PowerPak
https://www.powerpak.com/login
› login
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61 CLARINS® | Beauty Products, Cosmetics, Makeup, Body Care ...
https://www.clarins.co.uk/

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62 Osteoimmunology: Interactions of the Immune and skeletal ...
https://books.google.com/books?id=B9KVFiJCc9kC&pg=PA87&lpg=PA87&dq=serum+transfer+arthritis+model&source=bl&ots=J7i4PJeO9Y&sig=ACfU3U0Gp9IGAN4nu3l8l142WGMwHePmWw&hl=en&sa=X&ved=2ahUKEwjOsuPM49j7AhWwMlkFHRnxAaAQ6AF6BQj9ARAD
An important step in the etiology of arthritis is the alteration of ... mice still develop inflammation in the K/B×N serum transfer arthritic model, ...
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63 New Insights into Rheumatoid Arthritis, An Issue of ...
https://books.google.com/books?id=S-HkqVBw4IEC&pg=PT193&lpg=PT193&dq=serum+transfer+arthritis+model&source=bl&ots=zCBEm85ZCw&sig=ACfU3U1w0ofKt_D5VdhLUhWL6ebdXQJc3g&hl=en&sa=X&ved=2ahUKEwjOsuPM49j7AhWwMlkFHRnxAaAQ6AF6BQjrARAD
... of 50% reduction in clinical arthritis activity in the K/BxN serum transfer model.2 Cadherin-11 has been explored as a possible therapeutic target using ...
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64 Joint Diseases: Advances in Research and Treatment: 2011 Edition
https://books.google.com/books?id=V04oUPTBcF8C&pg=PA47&lpg=PA47&dq=serum+transfer+arthritis+model&source=bl&ots=LjNEk-h-os&sig=ACfU3U28fKhhlAn9RGdo_8oTk2kDvE4qCA&hl=en&sa=X&ved=2ahUKEwjOsuPM49j7AhWwMlkFHRnxAaAQ6AF6BQjuARAD
In the K/BxN mouse model of inflammatory arthritis, T cells initiate disease by ... into B-cell-deficient hosts enhanced K/BxN serum-transferred arthritis, ...
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65 Pain in Rheumatic Diseases, An Issue of Rheumatic Disease ...
https://books.google.com/books?id=lMcpEAAAQBAJ&pg=PT126&lpg=PT126&dq=serum+transfer+arthritis+model&source=bl&ots=jC8qkaQb7f&sig=ACfU3U3RyJQEAoyC1wiREf5esACnJ0S_aw&hl=en&sa=X&ved=2ahUKEwjOsuPM49j7AhWwMlkFHRnxAaAQ6AF6BQjsARAD
99–101 Preclinical animal models of RA have been used to understand the pain ... The K/BxN passive serum transfer model of polyarthritis is induced by the ...
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66 Journal of the American Medical Association
https://books.google.com/books?id=4vI7AQAAMAAJ&pg=PA1803&lpg=PA1803&dq=serum+transfer+arthritis+model&source=bl&ots=ujimtXS8h9&sig=ACfU3U2LwuG0Zl4mTHDzWFWrGJ503yxpXQ&hl=en&sa=X&ved=2ahUKEwjOsuPM49j7AhWwMlkFHRnxAaAQ6AF6BQj-ARAD
Transfer the child at once to a large tub containing eight inches of water at 108 ... Vaccines in Treatment of Tuberculosis and Nontuberculous Arthritis .
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