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1 Lower glutamate and GABA levels in auditory cortex ... - Nature
https://www.nature.com/articles/s41598-022-07835-8
Miyakawa and colleagues induced tinnitus in a knockout mouse model through the inhibition of Glutamate decarboxylase 65 (GAD65) expression.
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2 Neurotoxins and Tinnitus – Aspartame, MSG & Solutions
https://www.tinnitusformula.com/library/neurotoxins-and-tinnitus-aspartame-msg-solutions/
Many treatments including Arches Tinnitus Formula™ use ingredients that work as glutamate antagonists, or inhibitors. In this article, we will look at the ...
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3 Glutamate Antagonists, Steroids, and Antioxidants as ...
https://www.tinnitusjournal.com/articles/glutamate-antagonists-steroids-andantioxidants-as-therapeutic-options-forhearing-loss-and-tinnitus-and-the-use-ofan-inner-ear-drug.pdf
This article discusses the use of glutamate antagonists, steroids, and antioxidants for the man- agement of hearing loss and tinnitus. Additionally, the results ...
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4 Tinnitus Correlates with Downregulation of Cortical Glutamate ...
https://www.jneurosci.org/content/39/50/9989
Knocking down GAD65 expression in the AI resulted in tinnitus in normal-hearing FVB mice. Our results suggest that reduced inhibitory neuronal ...
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5 Glutamate receptor antagonists for tinnitus - Imsuwansri, T
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD012391/full
The objectives are as follows: To evaluate the effects and safety of glutamate receptor antagonist medications prescribed for tinnitus.
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6 Effects of two inhibitors of metabolic glutamate receptor 5 on ...
https://www.tandfonline.com/doi/full/10.1080/21655979.2021.1979354
MPEP significantly reduced tinnitus scores and suppressed Homer1 expression in a concentration dependent manner. MCPG had no significant effects on tinnitus ...
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7 Noise Exposure Alters Glutamatergic and GABAergic Synaptic ...
https://www.hindawi.com/journals/np/2021/8833087/
In resistant animals, inhibitory synapse density recovered to preexposure levels, but in animals expressing tinnitus, inhibitory synapse density remained ...
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8 How Do Otic NMDA Antagonists Work? - RxList
https://www.rxlist.com/how_do_otic_nmda_antagonists_work/drug-class.htm
The first otic NMDA antagonist is in clinical trial pending approval for treatment of acute inner ear tinnitus following acute acoustic trauma ...
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9 Treatment of tinnitus using glutamate receptor agonists
https://patents.google.com/patent/WO2017142543A1/en
A method of screening a subject having tinnitus for treatment with a group II mGluR agonist that includes testing the use of residual inhibition to suppress ...
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10 Nootropics for Tinnitus - Balance Brain Chemicals for Healthy ...
https://www.mindlabpro.com/blogs/nootropics/nootropics-tinnitus
Glutamate controls communication between auditory centers in the brain and the inner hair cells of the cochlea. When these hair cells become ...
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11 Involvement of Oxidative Stress, Inflammation, and Glutamate ...
https://clinmedjournals.org/articles/ijnn/international-journal-of-neurology-and-neurotherapy-ijnn-6-083.php?jid=ijnn
This imbalance in neurotransmission can cause hyperactivity in the auditory cortex leading to the perception of phantom sounds (tinnitus). Intense noise causes ...
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12 Gamma-aminobutyric acid and glutamic acid levels ... - Frontiers
https://www.frontiersin.org/articles/10.3389/fnsys.2012.00009/full
To examine the roles of GABA and Glu in tinnitus, high resolution ... as that mediated by the excitatory neurotransmitter glutamate (Glu).
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13 Cochlear NMDA Receptors as a Therapeutic Target of Noise ...
https://www.karger.com/Article/Fulltext/374000
Background: Accumulating evidence suggests that tinnitus may occur despite normal auditory sensitivity, probably linked to partial degeneration ...
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14 treatment of tinnitus using glutamate receptor agonists
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2017142543
› search › detail
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15 Residual inhibition: From the putative mechanisms to potential ...
https://www.sciencedirect.com/science/article/pii/S0378595518304635
This suppression is mediated by metabotropic glutamate receptors (mGluRs). Lastly, drugs targeting mGluRs suppress spontaneous activity in auditory neurons and ...
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16 Effects of two inhibitors of metabolic glutamate receptor 5 on ...
https://www.researchgate.net/publication/354743369_Effects_of_two_inhibitors_of_metabolic_glutamate_receptor_5_on_expression_of_endogenous_homer_scaffold_protein_1_in_the_auditory_cortex_of_mice_with_tinnitus
MPEP significantly reduced tinnitus scores and suppressed Homer1 expression in a concentration dependent manner. MCPG had no significant effects ...
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17 Tinnitus discovery could lead to new ways to stop the ringing
https://news.berkeley.edu/2011/09/12/tinnitus-discovery-could-lead-to-new-ways-to-stop-the-ringing/
His experiments showed that tinnitus is correlated with lower levels of the inhibitory neurotransmitter GABA (gamma-aminobutyric acid), but not ...
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18 Treatment Effects of Glutamate Antagonist for Tinnitus
http://repository.ajou.ac.kr/handle/201003/5224
There was no difference between the response group and the non-response group in age, sex, site, and tinnitus characteristics. Conclusion: We suggest that ...
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19 Local NMDA Receptor Blockade Attenuates Chronic Tinnitus ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077674
Recently it was shown that glutamatergic blockade in the cerebellar paraflocculus, using an antagonist cocktail was successful in reducing ...
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20 31+ Ways To Combat And Fix Tinnitus (With Mechanisms)
https://mybiohack.com/blog/tinnitus-fix-gaba-glutamate-supplements
For example, glutamate (an excitatory neurotransmitter) may be ... that help tinnitus in animal models are active via tonic inhibition.
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21 [PDF] Glutamate Antagonists, Steroids, and Antioxidants as ...
https://www.semanticscholar.org/paper/Glutamate-Antagonists%2C-Steroids%2C-and-Antioxidants-Seidman/711569fccb72971bb4dfbfd1925862e2a54502a2
Glutamate Antagonists, Steroids, and Antioxidants as Therapeutic Options for Hearing Loss and Tinnitus and the Use of an Inner Ear Drug Delivery System.
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22 What's the buzz? The neuroscience and the treatment of tinnitus
https://journals.physiology.org/doi/full/10.1152/physrev.00029.2020
Residual inhibition can be due to suppression of spontaneous firing in central auditory neurons, and metabotropic glutamate receptors ...
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23 Treatment Effects of Glutamate Antagonist for Tinnitus.
https://www.kjorl.org/m/makeCookie.php?url=/m/journal/view.php?number=2537
... hydrochloride and memantine hydrochloride for tinnitus treatment and to determine their appropriate indication of glutamate antagonist therapy.
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24 The sensorineural hearing loss model of tinnitus | Oxford
https://academic.oup.com/book/4681/chapter/146864700
Shortly after the trauma restoration of the excitatory-inhibitory balance can ... of glutamate, influx of large quantities of Ca2+ ions in the postsynaptic ...
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25 Memantine Attenuates Salicylate-induced Tinnitus Possibly by ...
https://www.en-journal.org/journal/view.html?uid=466
Memantine, a noncompetitive antagonist of the N -methyl- d -aspartate (NMDA) receptor, suppresses the release of excessive levels of glutamate ...
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26 Propofol‐Interrupted Tinnitus Later Suppressed by Amantadine
https://accp1.onlinelibrary.wiley.com/doi/pdf/10.1002/jcph.6
glutamatergic synaptic transmission. Amantadine, another glutamate antagonist, was later prescribed and durably suppressed tinnitus. Systematically.
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27 Neuroprotective Effect of Valproic Acid on Salicylate-Induced ...
https://www.mdpi.com/1422-0067/23/1/23
Effective inhibition of NMDA receptors may be a potential therapeutic strategy for tinnitus [15]. Once the neurons are stressed due to chronic glutamate ...
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28 Excitatory and Inhibitory Neurotransmission in - UConn Health
https://health.uconn.edu/meds5377/wp-content/uploads/sites/151/2017/07/First-Lecture-Salamanca-NTs-of-the-AUD-CANS.pdf
Tinnitus and Aging: Loss of Acoustic Input and ... Transmitters: glutamate, glycine and GABA are ... Glutamate is cleared from the synapse by excitatory.
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29 How do we cure tinnitus? A hunt for answers
https://www.physoc.org/blog/how-do-we-cure-tinnitus-a-hunt-for-answers-a-member-spotlight/
We recently showed that noise exposure, a common cause of hearing loss and tinnitus, oppositely affects glutamate release at the auditory and ...
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30 Any Supplement or Medicine That Can Reduce Tinnitus ...
https://www.tinnitustalk.com/threads/any-supplement-or-medicine-that-can-reduce-tinnitus-caused-by-a-glutamate-storm.13833/
It's all very complex and poorly understood. Glutamate is required for the biosynthesis of GABA... Presumedly, most tinnitus is caused by a ...
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31 New Trends in Tinnitus Management
https://openneurologyjournal.com/VOLUME/5/PAGE/12/FULLTEXT/
Caroverine acts as a glutamate antagonist. Denk et al. [36] reported variable results in patients with tinnitus treated with caroverine. Ehrenberger et al.
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32 Investigation of the NMDA Antagonist Ketamine as a ...
https://clinicaltrials.gov/ct2/show/NCT03336398
Clinical trials are ongoing to test a glutamate NMDA receptor antagonist (called esketamine), which is injected into the inner ear. However, the ...
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33 Aspartame and Monosodium Glutamate—Two Often ...
https://hearinglosshelp.com/blog/aspartame-and-monosodium-glutamate-two-often-overlooked-causes-of-tinnitus/
by Neil Bauman, Ph.D. ... There are many causes of tinnitus. Some are well-known and obvious such as exposing your ears to excessive noise. Others ...
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34 Nitric oxide signalling underlies salicylate-induced increases ...
https://www.biorxiv.org/content/10.1101/2021.05.14.444151.full
The tinnitus-inducing agent salicylate reduces cochlear output but ... D.C. & Oliver, D.L. (2011) Expression of glutamate and inhibitory ...
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35 Tinnitus treatment with acamprosate: a double-blind study
http://otosul.com.br/tinnitus_treat.htm
Glutamate, the main excitatory neurotransmitter amino acid of the auditory ... the inhibitory GABA system, counting on the dual mechanism to treat tinnitus.
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36 Pharmacological Treatments for Tinnitus - KoreaMed Synapse
https://synapse.koreamed.org/articles/1044263
Glutamate is a major excitatory neurotransmitter within the cochlea and central auditory pathways. Disturbances of glutamatergic transmission ...
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37 What's the Buzz? Treatment Strategies in Chronic Subjective ...
https://www.mdedge.com/clinicianreviews/article/175844/otolaryngology/whats-buzz-treatment-strategies-chronic-subjective/page/0/4
Carbamazepine is a glutamate receptor antagonist that suppresses seizure activity. Based on prior research suggesting that spontaneous firing within the ...
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38 TRT vs Standard of Care: Outcomes for tinnitus control
https://www.ncrar.research.va.gov/Conference/Documents/PPT/Bauer.pdf
Goals of drug treatments for tinnitus ... Gabapentin significantly improves new onset tinnitus. (Zapp 2001) ... glutamate antagonist. - GABA agonist.
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39 Memantine Suppresses the Glutamatergic Neurotransmission ...
https://mediatum.ub.tum.de/doc/1218459/1218459.pdf
strong inhibiting effect on NMDA-induced activity but not on AMPA- ... that in tinnitus patients various cochlear dysfunctions like.
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40 Chapter - Determination of GABA, Glutamate and Choline in ...
https://www.eurekaselect.com/chapter/9578
However not everyone exposed to auditory trauma develops tinnitus. ... decreases in GABA (i.e., loss of inhibition) were not found in tinnitus animals.
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41 Tinnitus - The Lancet
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)60142-7/fulltext
Glutamate is the main excitatory neurotransmitter in the auditory system; consequently, various antagonist drugs have been investigated.
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42 Tinnitus - Medscape Reference
https://emedicine.medscape.com/article/856916-overview
Other antidepressants may be useful in treating tinnitus, but judgment in their use is paramount. Selective serotonin reuptake inhibitors ...
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43 ORIGINAL ARTICLE
https://jemds.com/data_pdf/5_sharanjeet.pdf
KEYWORDS: Sensorineural tinnitus, tinnitus matching, acamprosate ... both as a glutamate antagonist and as a GABA agonist reported a relief of tinnitus in ...
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44 Mechanisms of Noise-Induced Tinnitus: Insights from Cellular ...
https://www.cell.com/neuron/pdf/S0896-6273(19)30433-7.pdf
Inhibitory D-stellate neurons project to the contralateral CN ... alterations in vesicular glutamate transporters in the cochlear.
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45 Effect of Nitrous Oxide as a Treatment for Subjective ...
https://jamanetwork.com/journals/jamaotolaryngology/fullarticle/2688529
Nitrous oxide, a member of the NMDA receptor antagonist class, is a widely ... antagonist, ifenprodil, to abate the development of tinnitus ...
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46 Tinnitus treatment with acamprosate - SciELO
https://www.scielo.br/j/rboto/a/R7m8hLwpXDcNgP8JchwQHGS/?lang=en&format=pdf
Acamprosate acts both on the glutamatergic system. (excitatory) and in the inhibitory GABA system, counting on the dual mechanism to treat tinnitus.
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47 Role of acamprosate in sensorineural tinnitus - ProQuest
https://search.proquest.com/openview/0c88fb6e6cc284414196679c9451cd22/1?pq-origsite=gscholar&cbl=28295
Role of acamprosate in sensorineural tinnitus. Abstract. Acamprosate with dual mechanism of action as glutamate antagonist and GABA agonist can be a ...
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48 Mass Spectrometry Imaging Reveals Effect of Blasts on ...
https://hearinghealthfoundation.org/blogs/mass-spectrometry-imaging-reveals-effect-of-blasts-on-neurotransmitter-levels-in-the-chinchilla-model
This is mainly due to a poor understanding of the pathomechanism (causes) of tinnitus. An imbalance in the excitation and inhibition of ...
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49 Wbp2 is required for normal glutamatergic synapses in the ...
https://www.embopress.org/doi/10.15252/emmm.201505523
Wbp2 is required for normal glutamatergic synapses in the cochlea and is ... or peripheral tinnitus (Puel et al, 1994, 1998; Kujawa & Liberman, 2009).
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50 ajtr0084901.pdf - e-Century Publishing Corporation
https://e-century.us/files/ajtr/10/12/ajtr0084901.pdf
Changes in GABA and glutamate receptors on auditory cortical excitatory neurons in a rat model of salicylate-induced tinnitus.
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51 ear - TINNITUS - Dr. Meenesh Juvekar - ENT Specialist
https://specialist-ent.com/ear-tinnitus/
Mechanism of tinnitus by Glutamate: 1.Glutamate is a potent excitatory and highly neurotoxic on cochlear afferent. It is released at inner hair cell synaptic ...
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52 Auditory Deprivation, Inhibitory Circuits and Plasticity
http://arquivosdeorl.org.br/additional/acervo_eng.asp?id=341
Key words: hearing. neuronal plasticity, neural inhibition, tinnitus, hyperacusis ... Synapsis conducted by glutamate neurotrans¬mitter, for instance, ...
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53 Tinnitus treatment with acamprosate: double-blind study
http://www.bjorl.org/en-tinnitus-treatment-with-acamprosate-double-blind-articulo-S1808869415312660
Glutamate, the main excitatory neurotransmitter amino acid of the auditory ... the inhibitory GABA system, counting on the dual mechanism to treat tinnitus.
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54 Role of Free Radicals, Glutamate Toxicity, Glutathione ...
https://www.thieme-connect.com/products/ejournals/pdf/10.1055/s-0041-1724220.pdf
of tinnitus persisted, intratympanic steroid injection was given. ... dant level, inhibits glutamate release and reduces its toxicity.
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55 Current aspects of hearing loss from occupational and leisure ...
https://www.egms.de/en/journals/cto/2004-3/cto000006.shtml
Hearing loss and tinnitus can also occur separately. ... a glutamate antagonist with a broad spectrum of activity, clearly acts protectively ...
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56 Current view of neurotransmitter changes underlying tinnitus
https://journals.lww.com/nrronline/Fulltext/2015/10030/Current_view_of_neurotransmitter_changes.11.aspx
The idea that tinnitus may result from a decrease in inhibitory neurotransmission is not definitively supported by these results, in that types of cochlear ...
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57 When silencing phantom noises is a matter of science
https://www.eurekalert.org/news-releases/500431
"Dysfunctions in glutamate transporters has been previously associated with seizures and amyotrophic lateral sclerosis and now, tinnitus.".
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58 Noise-induced plasticity of KCNQ2/3 and HCN channels ...
https://elifesciences.org/articles/07242
Mice that successfully avoid developing tinnitus despite exposure to ... enhanced GABAergic tonic inhibition, enhanced glutamatergic ...
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59 Decreasing dorsal cochlear nucleus activity ameliorates noise ...
https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-022-01288-1
... decreased inhibition of startle, indicating tinnitus but without ... due to down-regulation of vesicular glutamate transport 1 (VGlut1; ...
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60 Axonal sprouting in the dorsal cochlear nucleus affects gap ...
https://www.spandidos-publications.com/10.3892/ijmm.2019.4316
Tinnitus is the perception of sound in the absence of an external source (1 ... the levels of vesicular glutamate transporter 1 (VGLUT1), ...
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61 Biomarkers in glaucoma and tinnitus suggest low nitric oxide ...
https://iovs.arvojournals.org/article.aspx?articleid=2766827
Conclusions : Low ARG and high ORN suggest a decrease in NO bioavailability in all patients. The high GLU in all patients and relatively high GLN in tinnitus ...
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62 Effectiveness of Ginkgo biloba in treating tinnitus: double blind ...
https://www.bmj.com/content/322/7278/73/rapid-responses
Dr. Temmel reminds us of trials with the glutamate antagonist caroverine performed at his clinic in 1997 (1). In the single-blinded
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63 Cochlear NMDA receptor blockade prevents salicylate ...
http://www.b-ent.be/Content/files/sayilar/77/2007-3-S7-019-Puel.pdf
inhibitor). Since NMDA antagonists also blocked mefenamate-induced tinnitus, we suggest that salicylate-induced tin- nitus is mediated by cochlear NMDA ...
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64 Neuronal hyperactivity: tinnitus and distress - Grantome
https://grantome.com/grant/NIH/R01-DC016918-02
We discovered that the mechanism of residual inhibition is likely explained by sound-evoked suppression of spontaneous firing in central auditory neurons, and ...
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65 Tinnitus Update - :: JCN :: Journal of Clinical Neurology
https://thejcn.com/DOIx.php?id=10.3988/jcn.2021.17.1.1
4) The socalled inhibitory gating mechanism blocks the tinnitus ... the administration of high-dose acamprosate, glutamate antagonist, ...
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66 OTO-313 Program Review - Investor Relations | Otonomy Inc
https://investors.otonomy.com/static-files/e6b38d5c-4095-4db8-a5b1-d68552ac0439
Rationale for NMDA Receptor Antagonist to Treat Tinnitus ... glutamate to activate NMDA receptors on ... Inhibition of over-excited SGNs.
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67 Role of acamprosate in sensorineural tinnitus Sharma DK ...
https://www.ijp-online.com/article.asp?issn=0253-7613;year=2012;volume=44;issue=1;spage=93;epage=96;aulast=Sharma
Acamprosate with dual mechanism of action as glutamate antagonist and GABA agonist can be a potential target to decrease the severity of ...
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68 Impact of Acamprosate on Chronic Tinnitus: A Randomized ...
https://www.metroatlantaotolaryngology.org/journal/sept21/Acamprosate&Tinnitus.pdf
of the excitatory and inhibitory neurotransmitters.2 ... such as glutamate.2-4 Various therapeutic strategies have been applied so far, but at present, ...
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69 Tinnitus Correlates with Downregulation of ... - CityU Scholars
https://scholars.cityu.edu.hk/en/publications/publication(f4735dd7-6488-4c4e-9261-80107ddbfcc2).html
Furthermore, knockdown of glutamate decarboxylase 65 (GAD65) expression in auditory cortex by RNA interference gave rise to tinnitus in normal- ...
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70 AudioGuard - Naveh Pharma Ltd.
https://www.navehpharma.com/products/magnesium-based-line/audioguard
AudioGuard - Helps in prevention of hear loss and tinnitus. ... Magnesium also protects the nerves in the inner ear and is a powerful glutamate inhibitor.
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71 Neurotransmitter Modulation Relates with Tinnitus ... - CORE
https://core.ac.uk/download/pdf/82335481.pdf
Glutamate is one of the most important excitatory ... In the inner ear, glutamate is released ... between decreased inhibitory activity and tinnitus.
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72 The Role of Inflammation in Tinnitus | Encyclopedia MDPI
https://encyclopedia.pub/entry/20167
TNF-α and IL-1β influence NMDA and GABA receptors, leading to an increased excitatory and decreased inhibitory neurotransmission. These changes can lead to ...
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73 L-Glutamine - Nootropics Expert
https://nootropicsexpert.com/l-glutamine/
Neurotransmitters. L-glutamine is a precursor to the excitatory amino acid and neurotransmitter glutamate and aspartate. And the inhibitory ...
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74 Neurotransmitter Modulation Relates with Tinnitus Signal ...
https://m.cafe.daum.net/panicbird/S3Cq/482?listURI=%2Fpanicbird%2FS3Cq
Recent studies have found that neurotransmitters or modulators, such as glutamate, γ-aminobutyric acid(GABA), serotonin, dynorphin, dopamine, ...
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75 Hearing Research - School of Behavioral and Brain Sciences
https://bbs.utdallas.edu/agingmemorylab/pdf/Kapolowicz&Thompson.2016.pdf
acute cochlear trauma, a common cause of tinnitus in humans and previously ... verting glutamate into the inhibitory neurotransmitter GABA,.
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76 Lower glutamate and GABA levels in auditory cortex of tinnitus ...
https://search.ebscohost.com/login.aspx?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=20452322&AN=155685045&h=hatQJ6BgKtOinAR4RwpoGHnEO6hNGxsU2oIpZqhjkQ2Q2Bu4RFD5Xh17PZdiO8mKn1eaPbh%2FzC0qcyFqOPjQUg%3D%3D&crl=f
inhibitory neurotransmitters in tinnitus. Two‑dimensional J‑resolved spectroscopy (2D‑JPRESS) was applied to disentangle Glutamate (Glu) from Glutamine and ...
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77 US20060063802A1 - Methods for the treatment of tinnitus ...
https://www.google.com/patents/US20060063802
In these methods, a pharmaceutical composition comprising an NMDA receptor antagonist is administered to an individual in need of such treatment by ...
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78 Hearing Research - Union College
https://minerva.union.edu/romeros/Cacace_et_al_2018.pdf
Glutamate is down-regulated and tinnitus loudness-levels decreased ... is thought to modulate cortical excitability via inhibitory mecha-.
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79 How magnesium may help prevent tinnitus | Life - News24
https://www.news24.com/health24/medical/hearing-management/tinnitus/how-magnesium-may-help-prevent-tinnitus-20160505
Tinnitus is caused by the “unregulated production of glutamate at sound frequencies for which there is no external stimulation”. Read: Which ...
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80 이명에 대한 Glutamate 길항제의 치료효과 - 한국학술지인용색인
https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART000855888
Treatment Effects of Glutamate Antagonist for Tinnitus - Tinnitus· Glutamate antagonists· Therapeutics.
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81 NMDA receptor antagonist - Wikipedia
https://en.wikipedia.org/wiki/NMDA_receptor_antagonist
› wiki › NMDA_receptor_anta...
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82 Glutamate Blockers for Vertigo - Dizziness-and-balance.com
https://dizziness-and-balance.com/treatment/drug/glutamate.html
Memantine is an uncompetitive antagonist at glutamatergic NMDA receptors, inhibiting influx of calcium ions. Since glutamate is an excitatory ...
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83 How to Increase GABA and Balance Glutamate
https://www.verywellhealth.com/treating-gaba-and-glutamate-dysregulation-716040
Theanine: This precursor of glutamate appears to lower glutamate activity in the brain by blocking receptors while also boosting GABA levels.
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84 GLAST deficiency in mice exacerbates gap detection deficits ...
https://psycnet.apa.org/record/2016-48520-001
Gap detection or gap pre-pulse inhibition of the acoustic startle (GPIAS) ... The glutamate aspartate transporter (GLAST) is expressed in ...
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85 Effects of two inhibitors of metabolic glutamate receptor 5 on ...
https://m.x-mol.com/paper/1440769683335475200?adv
Effects of two inhibitors of metabolic glutamate receptor 5 on expression of endogenous homer scaffold protein 1 in the auditory cortex of mice with tinnitus.
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86 Glutamate: What It Is & Function - Cleveland Clinic
https://my.clevelandclinic.org/health/articles/22839-glutamate
Glutamate is also needed for making another neurotransmitter in your brain called gamma-aminobutyric acid (GABA). GABA is known as the “calming” ...
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87 Medications That Can Cause Ear Ringing (Tinnitus) - GoodRx
https://www.goodrx.com/drugs/side-effects/these-11-prescriptions-may-cause-ringing-in-the-ears
Tinnitus, or ringing in the ears, is a side effect of many ... Angiotensin-converting enzyme (ACE) inhibitors are medications used to lower ...
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88 Tinnitus, causes, prevention, diagnosis, treatment & prognosis
https://healthjade.net/tinnitus/
Learn about tinnitus or ringing in ears. ... alters the balance between inhibition and excitation, and thus raises spontaneous neural activity in the ...
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89 Tinnitus cure 2025 - Kils
https://kils.it/tinnitus-cure-2025.html
Fax +49 941 941 2025 Tinnitus is a prevalent disorder that has no cure ... of the NMDA antagonist ketamine as a treatment for tinnitus Site PI: Folmer, DoD, ...
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90 How to heal gaba receptors reddit
https://ancvilladagri.it/how-to-heal-gaba-receptors-reddit.html
GABA is the brain's main inhibitory molecule – the “off” signal for neurons. ... One kind, synaptic GABA receptors, works in tandem with glutamate receptors ...
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91 Tinnitus: A Multidisciplinary Approach - Page 154 - Google Books Result
https://books.google.com/books?id=Ek3caYCiGfMC&pg=PA154&lpg=PA154&dq=glutamate+inhibitors+tinnitus&source=bl&ots=6wZYMb6GAe&sig=ACfU3U3Hn651nY1W2ExtDPP1qZIMPi3Bpg&hl=en&sa=X&ved=2ahUKEwiMiLrpmNn7AhUaqlYBHY41CR8Q6AF6BQjWAhAD
Zapp ( 2001 ) reported a single patient whose tinnitus improved while ... A small open trial of flupirtine, which is a glutamate antagonist but also active ...
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92 Tinnitus STOP!: The Complete Guide On Ringing In The Ears, ...
https://books.google.com/books?id=IHQsBwAAQBAJ&pg=PT28&lpg=PT28&dq=glutamate+inhibitors+tinnitus&source=bl&ots=RpCn5ftjvk&sig=ACfU3U2X3QgDCXslXl5r34lcfF4tEBVJHA&hl=en&sa=X&ved=2ahUKEwiMiLrpmNn7AhUaqlYBHY41CR8Q6AF6BQjXAhAD
The Complete Guide On Ringing In The Ears, Natural Tinnitus Remedies, ... condition is the neuroprotective agent known as glutamate antagonist Caroverine.
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93 Tinnitus: Pathophysiology and Treatment
https://books.google.com/books?id=XydUtbVHtdEC&pg=PA11&lpg=PA11&dq=glutamate+inhibitors+tinnitus&source=bl&ots=Qn3PJd_sK3&sig=ACfU3U3E15CHJ6W8sedP7iupUl_zM62NHQ&hl=en&sa=X&ved=2ahUKEwiMiLrpmNn7AhUaqlYBHY41CR8Q6AF6BQjLAhAD
The N-methyl-D-aspartic acid (NMDA) (glutamate) receptor is most likely also ... However, attempts to use NMDA receptor inhibitors (such as the MK801 ...
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94 The Behavioral Neuroscience of Tinnitus
https://books.google.com/books?id=bPk_EAAAQBAJ&pg=PA58&lpg=PA58&dq=glutamate+inhibitors+tinnitus&source=bl&ots=yd7HpDjK2M&sig=ACfU3U0XMzg-Tbj-5ED2gIDSnHa4FaK2yw&hl=en&sa=X&ved=2ahUKEwiMiLrpmNn7AhUaqlYBHY41CR8Q6AF6BQjMAhAD
increased glutamatergic neurotransmission in the acoustic trauma-induced ... in salicylate-induced tinnitus by testing another cyclooxygenase inhibitor, ...
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95 Neuronal Networks in Brain Function, CNS Disorders, and ...
https://books.google.com/books?id=AHUpAgAAQBAJ&pg=PA264&lpg=PA264&dq=glutamate+inhibitors+tinnitus&source=bl&ots=UHxmDzVkHd&sig=ACfU3U0615oCXDxU-mWYLR98MhK6h-W74Q&hl=en&sa=X&ved=2ahUKEwiMiLrpmNn7AhUaqlYBHY41CR8Q6AF6BQjPAhAD
In addition to loss of inhibition, tinnitus may also be mediated by an increase in ... The potential role of the excitatory glutamate system has been ...
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