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1 Immunoglobulin E Receptor - an overview - ScienceDirect.com
https://www.sciencedirect.com/topics/medicine-and-dentistry/immunoglobulin-e-receptor
There are two IgE receptors: FcεRI is the high-affinity IgE receptor that is expressed by mast cells and basophils and by dendritic cells and Langerhans cells ...
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2 IgE in Clinical Allergy and Allergy Diagnosis
https://www.worldallergy.org/education-and-programs/education/allergic-disease-resource-center/professionals/ige-in-clinical-allergy-and-allergy-diagnosis
Other cells known to express high-affinity receptors for IgE include basophils, Langerhans cells and activated monocytes. Production of allergen specific ...
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3 The biology of IgE - UpToDate
https://www.uptodate.com/contents/the-biology-of-ige/print
IgE plays a key role in the pathogenesis of allergic diseases, especially mast cell/basophil activation, and in antigen presentation. STRUCTURE.
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4 The Role of Immunoglobulin E in Allergy and Asthma
https://www.atsjournals.org/doi/10.1164/ajrccm.164.supplement_1.2103024
When antigen binds to the IgE variable regions of two adjacent antibodies on a mast cell or basophil, their receptors become physically cross- ...
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5 Immunoglobulin E - Wikipedia
https://en.wikipedia.org/wiki/Immunoglobulin_E
Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) "isotype") that has been found only in mammals. IgE is synthesised by plasma cells.
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6 Cytokinergic IgE Action in Mast Cell Activation - Frontiers
https://www.frontiersin.org/articles/10.3389/fimmu.2012.00229/full
(A) In the classical allergic response, multivalent allergens cross-link IgE-FcεRI complexes on the surface of mast cells to trigger mast cell ...
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7 Anti-IgE therapy for IgE-mediated allergic diseases
https://ctajournal.biomedcentral.com/articles/10.1186/s13601-018-0213-z
Apart from binding FcεRI on mast cells and basophils, IgE can also bind its low-affinity receptor FcεRII, which is expressed by B cells and ...
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8 Rethinking the Role of Immunoglobulin E and Its High-Affinity ...
https://www.karger.com/Article/Fulltext/365633
Immunoglobulin E (IgE) and its high-affinity receptor (FcεRI) are well-known participants in the allergic response.
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9 The role of Immunoglobulin E and immune inflammation
https://link.springer.com/article/10.1007/s11882-005-0045-5
Immunoglobulin E (IgE) plays a critical role in the allergic inflammatory process in diseases such as allergic rhinitis. Cross-linking IgE bound to its ...
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10 Dendritic cell-bound IgE functions to restrain allergic ... - Nature
https://www.nature.com/articles/mi201485
Antigen-mediated cross-linking of Immunoglobulin E (IgE) bound to mast cells/basophils via FcɛRI, the high affinity IgE Fc-receptor, ...
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11 Past, present, and future of anti‐IgE biologics - Guntern - Allergy
https://onlinelibrary.wiley.com/doi/full/10.1111/all.14308
In addition to the free form of IgE, B cells express membrane IgE (mIgE) that is part of the B-cell receptor (BCR) and contains an extracellular ...
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12 The rationale for treating allergic asthma with anti-IgE
https://err.ersjournals.com/content/16/104/61
IgE binds to high-affinity receptors (FcϵRI) on effector cells, such as mast cells and basophils. Allergen binds to IgE and initiates an inflammatory ...
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13 IgE Antibodies: From Structure to Function and Clinical ... - MDPI
https://www.mdpi.com/2073-4468/8/1/19
Immunoglobulin E (IgE) antibodies are well known for their role in mediating allergic reactions, and their powerful effector functions activated through ...
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14 IgE in allergy and asthma today
http://www.alergomed.org/uploads/1/0/0/2/10021998/lectura_prctica_-_ige_2.pdf
in the treatment of asthma and other allergic diseases ... Fc receptor for IgE) and CD23, as well as galectin-3 and several co-receptors for CD23,.
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15 4. IgE, mast cells, basophils, and eosinophils
https://www.jacionline.org/article/S0091-6749(02)91382-5/abstract
If these receptor-bound IgE molecules are aggregated on reexposure to specific allergen, these mast cells and basophils produce mediators that result in the ...
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16 Autoantibodies against the High-Affinity IgE Receptor as a ...
https://www.nejm.org/doi/full/10.1056/nejm199306033282204
It is known that the binding of antigen (allergen) to antigen-specific IgE on mast cells and basophils causes the cells to degranulate, ...
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17 Role of STAT6 in IgE Receptor/FcεRI-Mediated Late Phase ...
https://www.jimmunol.org/content/168/1/421
These cells are known to play a key role in allergic reactions by their ability to release proinflammatory vasoactive amines (e.g., histamine), arachidonic acid ...
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18 Preferential Signaling and Induction of Allergy-promoting ...
https://rupress.org/jem/article/197/11/1453/39669/Preferential-Signaling-and-Induction-of-Allergy
These findings demonstrate that perturbation of small numbers of IgE receptors on mast cells favors certain signals that contribute to a lymphokine response ...
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19 Role of Seasonal Allergen Exposure and Th-2 Cytokines - PLOS
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0001921
The high affinity IgE receptor, FcεRI, plays a key role in the immunological pathways involved in allergic asthma.
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20 Immunoglobulin E Receptor Signaling and Asthma
https://www.jbc.org/article/S0021-9258(20)78184-6/fulltext
Elevated IgE levels and increased IgE sensitization to allergens are central features of allergic asthma. IgE binds to the high-affinity Fcϵ ...
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21 Allergy and immunoglobulin E – an evolving understanding of ...
https://www.veterinaryirelandjournal.com/small-animal/279-allergy-and-immunoglobulin-e-an-evolving-understanding-of-the-relationship
Most of us were taught that an allergic reaction occurs with the aggregation of high affinity IgE receptors (FcεR1) on mast cells and basophils after ...
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22 HOW ALLERGIES WORK - Desentum
https://www.desentum.fi/how-allergies-work
The IgE antibodies bind to mast cells. The allergen cross-links them. This triggers the mast cells to release powerful chemicals like histamines. 3.
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23 IgE Generation and Mast Cell Activation - SAGE Journals
https://journals.sagepub.com/doi/pdf/10.1177/1721727x1401200103
IgE is an important marker for allergy and plays a central role in the induction of allergic diseases through its binding of the high affinity receptor on mast ...
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24 IgE-Mediated Food Allergies | Biotechnology and Allergenicity
https://passel2.unl.edu/view/lesson/d23fda63fd18/7
IgE-Mediated Food Allergies ... An allergic reaction involves the overactivity of several components of the body's immune system, as a result from exposure to an ...
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25 Does IgE Bind to and Activate Eosinophils from Patients with ...
https://journals.aai.org/jimmunol/article/162/11/6901/69362/Does-IgE-Bind-to-and-Activate-Eosinophils-from
Human eosinophils have been reported to express both the mRNA and protein for the high affinity IgE receptor (FcεRI); it is speculated that this receptor ...
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26 Antihistaminic Treatment, Allergen‐Specific Immunotherapy ...
https://www.intechopen.com/chapters/56386
Allergies mediated by immunoglobulin E (IgE) are the most common immunological hypersensitivity diseases. The prevalence has been continuously increasing in ...
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27 Triggers of IgE class switching and allergy development
https://www.tandfonline.com/doi/full/10.1080/07853890701449354
The immunoglobulin (IgE)‐mediated allergic reaction is one of the fastest and potentially most vigorous reactions mounted by the immune system, ...
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28 Approaches to target IgE antibodies in allergic diseases
https://hal.sorbonne-universite.fr/hal-02022741/document
The high affinity IgE receptor, FcεRI, is expressed on the surface of blood basophils. 132 and tissue resident mast cells; and on other cell ...
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29 Regulation of Trafficking and Signaling of the High Affinity IgE ...
https://mdpi-res.com/d_attachment/ijms/ijms-23-00788/article_deploy/ijms-23-00788.pdf?version=1641973716
candidate for therapeutic strategies in allergy and asthma, if targeting can be realized. Keywords: mast cell; IgE receptor; FcεRIβ; antisense therapy; ...
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30 Effect of Rhus verniciflua Extract on IgE-Antigen-Mediated ...
https://www.hindawi.com/journals/ecam/2019/6497691/
When an allergen crosslinks with IgE, the receptor is phosphorylated by the Src-kinase combined with the β subunit, initiating cell signaling [.
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31 Fetal mast cells mediate postnatal allergic ... - Science
https://www.science.org/doi/10.1126/science.aba0864
IgE crossed the placenta, dependent on the fetal neonatal Fc receptor (FcRN), and sensitized fetal MCs for allergen-specific degranulation. Both passive and ...
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32 Mast Cell Activation Syndrome (MCAS)
https://www.aaaai.org/conditions-treatments/related-conditions/mcas
In allergic reactions, this release occurs when the allergy antibody IgE, which is present on the mast cell surfaces, binds to proteins that cause allergies, ...
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33 The Biology of IgE and the Basis of Allergic Disease
https://www.annualreviews.org/doi/10.1146/annurev.immunol.21.120601.141103
An allergic reaction is initiated when an antigen crosslinks immunoglobulin E (IgE) antibodies bound to their high-affinity Fc receptor (FcεRI) on tissue ...
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34 The Process of an Allergic Reaction
https://cityallergy.com/allergy-university/about-allergies/the-process-of-an-allergic-reaction/
When an allergen (antigen) enters the immune system, the antigen binds to these IgE receptors on the surface of the cells. When the allergic individual is ...
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35 Human IgE monoclonal antibody recognition of mite allergen ...
https://academic.oup.com/pnasnexus/article/1/3/pgac054/6598869
Allergens are usually innocuous molecules but induce IgE antibody production in allergic subjects. Allergen cross-linking of IgE bound to its high affinity ...
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36 The high affinity IgE receptor-IgG1 Fc fusion protein (mKS ...
https://iovs.arvojournals.org/article.aspx?articleid=2767801
Purpose : Inhibition of IgE, a major factor in allergic reactions, is important for the treatment of allergic diseases, and anti-IgE antibodies such as ...
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37 IgE receptor signaling in food allergy pathogenesis.
https://www.semanticscholar.org/paper/IgE-receptor-signaling-in-food-allergy-Oettgen-Burton/1f51493a6948260f7f2e1b649e84f50ca98a2654
Semantic Scholar extracted view of "IgE receptor signaling in food allergy pathogenesis." by H. Oettgen et al.
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38 Structure and dynamics of IgE–receptor interactions
https://allergolyon.fr/wp-content/uploads/2020/08/0.10.2-Structure-and-dynamics-of-IgE%E2%80%93receptor-interactions-Fc%CE%B5RI-and-CD23Fc%CE%B5RII-2015.pdf
of many allergic reactions. Crosslinking of receptor-bound. IgE on mast cells or basophils by multivalent allergen leads to degranulation and the release of ...
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39 A novel mechanism of IgE regulation by IgE-allergen ...
https://www.worldallergyorganizationjournal.org/article/S1939-4551(20)30328-8/fulltext
Type I allergic inflammation is mediated by IgE that triggers inflammatory reactions when it has bound the high-affinity IgE receptor FcεRI present on mast ...
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40 Allergies and the Immune System - iBiology
https://www.ibiology.org/immunology/allergies/
Circulating IgE binds to receptors on the surface of mast cells or basophils. Upon subsequent exposure, the allergen will bind to IgE and trigger the release of ...
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41 Anti-IgE Receptor (FcɛR1α) Autoantibody ELISA Kit - EagleBio
https://eaglebio.com/product/anti-ige-receptor-fc%C9%9Br1%CE%B1-autoantibody-elisa-kit/
The enzymatic activity of the immunocomplex bound to the IgE receptor protein on the wall of the microtiter well is directly proportional to the amount of anti- ...
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42 147140 - Fc FRAGMENT OF IgE, HIGH AFFINITY I ... - OMIM
https://www.omim.org/entry/147140
The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity ...
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43 Humanized IgE/FcεR1 Mouse Model | Inflammation & Allergy
https://www.genoway.com/catalog/immune-targets/inflammation-allergy/human-ige-fcer1.htm
Mast cells were sensitized with human IgE overnight to load hFcεR1 receptors and degranulation was stimulated by cross-linking loaded receptors with anti-hIgE.
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44 IgE | biochemistry - Encyclopedia Britannica
https://www.britannica.com/science/IgE
…known as immunoglobulin E (IgE). This response usually is triggered by a protein in the food that acts as an allergen. Through sensitization to the particular ...
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45 New treatment for allergic response targets mast cells
http://www.inunimai.org/cms/index.php/en/new-treatment-for-allergic-response-targets-mast-cells-en
When you come into contact with an allergen -- ragweed, for example -- immunoglobulin E (IgE) specific to that allergen acts through its receptor on the mast ...
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46 MECHANISMS IN NON-IGE-MEDIATED FOOD ALLERGY ...
https://journals.lww.com/jpgn/Fulltext/2004/06001/Mechanisms_in_Non_Ige_Mediated_Food_Allergy_and.1415.aspx
Mast cell and eosinophil activation is an important component of the non-IgE-mediated response. Degranulation of tissue mast cells can be seen within tissues, ...
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47 Design of a Heterobivalent Ligand to Inhibit IgE Clustering on ...
https://www.cell.com/ccbio/pdf/S1074-5521(11)00239-0.pdf
Mast cells are the major effector cells that mediate allergic responses. Cross-linking of. IgE bound to its high-affinity receptor (FcεRI) on ...
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48 Allergy Models - Allergenic IgE Monoclonal Antibodies/OVA ...
https://www.chondrex.com/animal-models/allergenic-ige-monoclonal-antibodies
The type I hypersensitivity reaction mediated by IgE antibodies is a typical clinical feature of allergic diseases, such as asthma, eczema, hay fever, and ...
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49 Immunology | EvolutionShorts - ScholarBlogs
https://scholarblogs.emory.edu/evolutionshorts/tag/immunology/
Once the allergen enters the body, it will be recognized by and bind to serum immunoglobulin E (IgE) – antibodies found in the lungs, skin, and ...
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50 View of Immunoglobulin E associated systemic conditions
https://pulmonarychronicles.com/index.php/pulmonarychronicles/article/view/573/1233
It also has a role in the process of immune regulation and, therefore, is related to the pathogenesis of allergic diseases. ... IgE exerts these effects by ...
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51 IgE-mediated Hypersensitivity Against Human Sweat Antigen ...
https://www.medicaljournals.se/acta/download/10.1080/000155502320624050/
allergic rhinitis without atopic dermatitis, urticaria or asthma; and 27 healthy volunteers ... which recognizes an epitope on the high af®nity IgE receptor.
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52 Immunoglobulin E (IgE), Serum - Mayo Clinic Laboratories
https://www.mayocliniclabs.com/test-catalog/Overview/8159
Evaluation of patients with suspected diseases associated with elevations in total immunoglobulin E (IgE), including allergic disease, ...
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53 FAQs about Anti-IgE Treatment - National Jewish Health
https://www.nationaljewish.org/conditions/medications/asthma-medications/longterm/faqs-anti-ige-treatment
Pre-made IgE against these allergens attaches to them and tells the rest of the immune cells to initiate an allergic reaction. This may bring on symptoms such ...
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54 IgE and mast cells in allergic disease - Read by QxMD
https://read.qxmd.com/read/22561833/ige-and-mast-cells-in-allergic-disease
Immunoglobulin E (IgE) antibodies and mast cells have been so convincingly linked to the pathophysiology of anaphylaxis and other acute ...
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55 IgE-mediated food allergy and allergic rhinitis - RACGP
https://www.racgp.org.au/afp/2014/october/hot-topics-in-paediatric-immunology-ige-mediated-f
At least 170 foods have been reported to cause IgE-mediated food allergies; however, more than 90% of allergic reactions in children are related to eight items: ...
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56 Linkage of high-affinity IgE receptor gene with bronchial ...
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(95)91863-9/fulltext
Some pedigree studies of atopy have suggested linkage with the high-affinity IgE receptor (Fc∈ Rlβ) gene on chromosome 11q13, ...
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57 How IgE mediates an allergic reaction via interaction with its ...
https://www.researchgate.net/figure/How-IgE-mediates-an-allergic-reaction-via-interaction-with-its-two-receptors-Left_fig7_279302130
How IgE mediates an allergic reaction via interaction with its two receptors. (Left) Interactions of membrane-bound IgE (mIgE, blue) with CD23 (tangerine) ...
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58 Original Article: Basic and Translational Allergy Immunology
https://journalallergy.com/Basic-and-Translational
Specific IgE against the house dust mite allergens Der p 5, 20 and 21 influences ... Dual activation of estrogen receptor alpha and glucocorticoid receptor ...
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59 THE HIGH AFFINITY IGE RECEPTOR (FCεRI)
https://journals.physiology.org/doi/prev/20171106-aop/epdf/10.1152/ajplung.00005.2006
2-FcεR NETWORK AND ALLERGIC ASTHMA. 2.1-The high affinity receptor for IgE: FcεRI. 2.2-The Low affinity receptor for IgE:CD23/FcεRII.
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60 알레르기 염증에서의 비만세포 역할과 비만세포 관련 질환
https://aard.or.kr/DOIx.php?id=10.4168/aard.2017.5.5.248
These mediators are released after IgE receptor cross-linking induced by allergens or other stimuli, including anaphylatoxins (C3a and C5a), ...
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61 Estimation of serum immunoglobulin E (IgE) level in allergic ...
https://www.primescholars.com/articles/estimation-of-serum-immunoglobulin-e-ige-level-in-allergic-asthma-andallergic-rhinitis-patients-before-and-after-treatment.pdf
wheezing, cough etc. through H1 receptor. Estimation of Ig E may be an important one in treatments for allergy and asthma.
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62 IgE receptor polymorphism predicts divergent, sex-specific ...
https://www.biorxiv.org/content/10.1101/841825v1.full
We identify a polymorphism in the Immunoglobulin E (IgE) receptor with sexually dimorphic ... particularly allergy (Tomassini et al., 1991).
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63 IgE receptor-activated calcium permeability pathway in rat ...
https://pubs.acs.org/doi/10.1021/bi00396a021
IgE receptor-activated calcium permeability pathway in rat basophilic ... Herbal Formula-3 inhibits food allergy in rats by stabilizing mast ...
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64 Allergens, Food, Common Adult Food IgE
https://ltd.aruplab.com/Tests/Pub/0050486
Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of ...
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65 New technologies and recent advances in the study of T cells ...
https://www.news-medical.net/news/20221128/New-technologies-and-recent-advances-in-the-study-of-T-cells-and-T-cell-epitope-discovery-in-food-allergy-research.aspx
Antigen-specific T-cells are inherently associated with both sensitization and tolerance to food allergens in IgE and non–IgE-mediated forms ...
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66 Urticaria and angioedema - Northwestern Scholars
https://www.scholars.northwestern.edu/en/publications/urticaria-and-angioedema
Furthermore, studies have revealed a circulating IgG antibody directed against the IgE receptor (F CεRIα) or IgE in 40-60% of patients with ...
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67 Study on mechanism of increased allergenicity induced by Ara ...
https://doi.org/10.1016/j.fshw.2022.09.009
As expected, compared with the control group, the BALB/c mice sensitized with raw peanuts cultivate IgE antibodies peanut allergens, and the serum IgE antibody ...
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68 Allergic Response Part 1
http://what-when-how.com/acp-medicine/allergic-response-part-1/
IgE receptors and regulation of igE ... Receptors for IgE (FceR) are expressed on various cells.21 The high-affinity receptor for IgE, FceRI, has two forms that ...
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69 Hives: Allergic Reaction Michigan
https://www.aaacr.com/what-we-treat/hives.html
30 to 50% of patients who have chronic hives lasting more than 6 weeks frequently have an autoimmune disease with antibodies to thyroid proteins or IgE receptor ...
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70 Allakos Announces Publication of AK006 ... - Yahoo Finance
https://www.yahoo.com/now/allakos-announces-publication-ak006-mechanism-120200089.html
... receptors present on immune effector cells involved in allergy, ... including IgE, IL-33, KIT, C5a, and MRGPRX2, resulting in the broad ...
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71 Allakos Announces Publication of AK006 Mechanism of Action
https://www.globenewswire.com/news-release/2022/11/29/2563877/0/en/Allakos-Announces-Publication-of-AK006-Mechanism-of-Action-Manuscript-in-Communications-Biology.html
... receptors present on immune effector cells involved in allergy, ... including IgE, IL-33, KIT, C5a, and MRGPRX2, resulting in the broad ...
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72 New Trends in Allergy II - Page 32 - Google Books Result
https://books.google.com/books?id=jRb2CAAAQBAJ&pg=PA32&lpg=PA32&dq=ige+receptor+allergy&source=bl&ots=m8pLYhyFAY&sig=ACfU3U02CUttzz8hgTH_x52aB4nYZnyxrQ&hl=en&sa=X&ved=2ahUKEwjKu6ibtdn7AhWoIzQIHU89C2oQ6AF6BQjdAhAD
J Biol Chem 259:1212 Kulczycki A Jr (1981) Role of IgE and IgE receptors in bronchial asthma. J Allergy Clin Immunol 68:5 Ishizaka T, Ishizaka K, Conrad DH, ...
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73 Allergy and Allergen Immunotherapy: New Mechanisms and ...
https://books.google.com/books?id=iSZdDgAAQBAJ&pg=PA472&lpg=PA472&dq=ige+receptor+allergy&source=bl&ots=frIDSzxm6M&sig=ACfU3U2kk-4yjFkD6l7IPawXfXiZ98JSbg&hl=en&sa=X&ved=2ahUKEwjKu6ibtdn7AhWoIzQIHU89C2oQ6AF6BQjfAhAD
The primary role is played by IgE in type I hypersensitivity reactions, where it binds to high-affinity IgE receptors (FcεRI) on mast cells and basophils.
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74 Allakos (ALLK) Announces Publication of AK006 Mechanism ...
https://www.streetinsider.com/Corporate+News/Allakos+%28ALLK%29+Announces+Publication+of+AK006+Mechanism+of+Action+Manuscript+in+Communications+Biology/20906016.html
... receptors present on immune effector cells involved in allergy, ... including IgE, IL-33, KIT, C5a, and MRGPRX2, resulting in the broad ...
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75 Type I Hypersensitivity: Overview Video - Medscape
https://www.medscape.com/viewarticle/942238
Type I hypersensitivity reactions are immediate and mediated by immunoglobulin (IgE) antibodies. The antigen—such as allergens like pollen ...
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76 Allakos Announces Publication of AK006 Mechanism ... - KTSM
https://www.ktsm.com/business/press-releases/globenewswire/8704540/allakos-announces-publication-of-ak006-mechanism-of-action-manuscript-in-communications-biology
Siglec-6 is an inhibitory receptor selectively expressed on mast cells. ... receptors present on immune effector cells involved in allergy, ...
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77 Allakos Announces Publication of AK006 ... - El Paso Inc.
https://www.elpasoinc.com/allakos-announces-publication-of-ak006-mechanism-of-action-manuscript-in-communications-biology/article_07d62f82-1654-5548-ac7e-67d666ef8fe0.html
... receptors present on immune effector cells involved in allergy, ... AK006 targets Siglec-6, an inhibitory receptor expressed selectively ...
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78 Tezepelumab for Severe Uncontrolled Asthma | JAA
https://www.dovepress.com/tezepelumab-for-patients-with-severe-uncontrolled-asthma-a-systematic--peer-reviewed-fulltext-article-JAA
Inhibiting TSLP, CCR3, IL-5, PGD2, IL-4, IL-13, IL-9 and/or IgE may be effective in the management of allergic eosinophilic asthma. Tezepelumab ...
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79 Asthme Bronchique Gina 2013
https://immunooncology.bms.com/fulldisplay?ID=91644&FileName=Asthme%20Bronchique%20Gina%202013.pdf
Allergy Frontiers:Clinical Manifestations. Aerosols in Medicine ... “Neuropeptide S receptor ... recognition of IgE profiles.
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80 Diagnostics Lab Test A-Z List | Medical Tests - Dr Lal PathLabs
https://www.lalpathlabs.com/tests-list.aspx
A ; ACETYLCHOLINE RECEPTOR (ACHR) MODULATING ANTIBODY · ANTI-ds DNA ANTIBODY, EIA · ALLERGY: ONION (Pyaaz) ; ACETYLCHOLINESTERASE, AMNIOTIC FLUID · ANTI ...
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81 2022-11-29 | NDAQ:ALLK | Press Release | Allakos Inc.
https://stockhouse.com/news/press-releases/2022/11/29/allakos-announces-publication-of-ak006-mechanism-of-action-manuscript-in
Siglec-6 is an inhibitory receptor selectively expressed on mast cells. ... receptors present on immune effector cells involved in allergy, ...
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82 Patient Dashboard | Sonora Quest Laboratories
https://www.sonoraquest.com/patient/?page=my-bills
... Aldosterone ALK Mutation (Gene Rearrangement) Allergy Blood Testing ALP ... Viral Load HLA Testing HLA-B27 Home Tests Homocysteine HPV hs-CRP HTLV IgE, ...
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83 Allakos Announces Publication - GuruFocus.com
https://www.gurufocus.com/news/1900728/allakos-announces-publication-of-ak006-mechanism-of-action-manuscript-in-communications-biology
Siglec-6 is an inhibitory receptor selectively expressed on mast cells. ... including IgE, IL-33, KIT, C5a, and MRGPRX2, resulting in the ...
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84 Allakos Announces Publication of AK006 Mechanism of Action ...
https://www.benzinga.com/pressreleases/22/11/g29884641/allakos-announces-publication-of-ak006-mechanism-of-action-manuscript-in-communications-biology
... targets the mast cell inhibitory receptor Siglec-6 –– AK006 shows ... receptors present on immune effector cells involved in allergy, ...
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85 IgE in allergy and asthma today - Document - Gale OneFile
https://link.gale.com/apps/doc/A190463139/HRCA?u=googlescholar&sid=googleScholar&xid=a4d4eefc
The activity of IgE is associated with a network of proteins; prominent among these are its two principal receptors, FC[epsilon]RI (high-affinity Fc receptor ...
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86 MedicalResearch.com |
https://medicalresearch.com/tag/medical-research/
Upon IgE binding an allergen, mast cells produce tons of histamine which can cause symptoms like itching. So we speculated that perhaps because patients with ...
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87 Middleton's Allergy E-Book: Principles and Practice
https://books.google.com/books?id=qefTAAAAQBAJ&pg=PA254&lpg=PA254&dq=ige+receptor+allergy&source=bl&ots=8XDpoLPivl&sig=ACfU3U3bvGyRHMLpe3r2DGDrJY2PYj9qXw&hl=en&sa=X&ved=2ahUKEwjKu6ibtdn7AhWoIzQIHU89C2oQ6AF6BQjbAhAD
This is an important aspect to consider in light of anti-IgE therapy for the treatment of allergic disease. With just an estimated 200 IgE-receptor ...
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88 IgE and Anti-IgE Therapy in Asthma and Allergic Disease
https://books.google.com/books?id=SdfKBQAAQBAJ&pg=PA33&lpg=PA33&dq=ige+receptor+allergy&source=bl&ots=K4VrPpGAjG&sig=ACfU3U2NOoxMW1rG2iW_DSRE__CMSReJFQ&hl=en&sa=X&ved=2ahUKEwjKu6ibtdn7AhWoIzQIHU89C2oQ6AF6BQjeAhAD
Hakimi J, Seals C, Kondas JA, Pettine L, Danho W, Kochan J. The α subunit of the human IgE receptor (FcERI) is sufficient for high affinity IgE binding.
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89 R718 Mouse Anti-Human Basophils (2D7) - BD Biosciences
https://www.bdbiosciences.com/en-ie/products/reagents/flow-cytometry-reagents/research-reagents/single-color-antibodies-ruo/r718-mouse-anti-human-basophils-2d7.568381
Basophils express high levels of FceRI, a high affinity receptor for IgE. ... allergic diseases, including anaphylaxis, asthma, and atopic dermatitis.
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90 Tanggal Pendaftaran Calon Mahasiswa Unlam
https://log.mienvio.mx/trackid?context=99617&FileName=Tanggal%20Pendaftaran%20Calon%20Mahasiswa%20Unlam.pdf
molecular understanding of immunodeficiency CCR5 co-receptor for HIV therapeutic benefit of monoclonal anti-IgE in allergy the.
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