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Google Keyword Rankings for : dependent central antitussives

1 Antitussive Agent - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/antitussive-agent
Antitussives constitute a heterogeneous class of compounds that inhibit cough through either a central or a peripheral mechanism, or a mixture of the two.
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2 Influence of central antitussive drugs on the cough motor pattern
https://journals.physiology.org/doi/10.1152/jappl.1999.86.3.1017
Central antitussive drugs primarily suppress cough by inhibition of ... Significant, dose-dependent decreases in cough number and rectus abdominis EMG ...
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3 Central and peripheral mechanisms of narcotic antitussives
https://coughjournal.biomedcentral.com/articles/10.1186/1745-9974-3-8
Narcotic antitussives such as codeine reveal the antitussive effect primarily via the μ-opioid receptor in the central nervous system (CNS).
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4 Central vs. peripheral sites of action of antitussive agents in ...
https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.23.1_supplement.1011.3
Dextromethorphan (DEX), SKF10047, codeine, DAMGO, mexiletine and baclofen have all been reported to prevent cough, in part, through direct ...
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5 Antitussive Agents | DrugBank Online
https://go.drugbank.com/categories/DBCAT000738
› categories › DBCAT000738
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6 Antitussives - Nursing Pharmacology Study Guide - Nurseslabs
https://nurseslabs.com/antitussives/
Acts directly on the medullary cough center of the brain to depress the cough reflex. · Because they are centrally acting, they are not the drugs ...
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7 Use of antitussive medications in acute cough in young children
https://www.acep.org/globalassets/new-pdfs/preps/use-of-antitussive-medications-in-acute-cough-in-young-children.pdf
1 Department of Emergency Medicine, Sutter Medical Center Sacramento ... dependency.48 Moreover, most OTC antitussives are available as com-.
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8 The Pharmacology of Peripherally Active Antitussive Drugs
https://link.springer.com/chapter/10.1007/978-3-540-79842-2_8
by D Spina · 2009 · Cited by 15 —
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9 Antitussive Cough (DM) Oral: Uses, Side Effects, Interactions ...
https://www.webmd.com/drugs/2/drug-144109/antitussive-cough-dm-oral/details
Dextromethorphan is a cough suppressant that affects a certain part of the brain (cough center), reducing the urge to cough. Decongestants help relieve stuffy ...
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10 The pharmacology of cough.pdf
http://physiology.elte.hu/gyakorlat/cikkek/The%20pharmacology%20of%20cough.pdf
Current antitussive drugs are divided broadly according to their site of action as either central or peripheral, although many antitussives act ...
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11 ANTITUSSIVE HYCODAN® (Hydrocodone Bitartrate and ...
https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/005213s038lbl.pdf
Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) ... Hydrocodone can produce drug dependence of the morphine type and, ...
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12 Current and future drugs for the treatment of chronic cough
https://thorax.bmj.com/content/thoraxjnl/59/5/438.full.pdf
The most effective antitussive agents are opioids ... they also cause physical dependence, respiratory ... most commonly used antitussive in the USA.
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13 Addictive evaluation of cholic acid-verticinone ester, a ... - Nature
https://www.nature.com/articles/aps200943
This study was carried out to investigate the central antitussive mechanism ... Lastly, we determined the opioid dependence of CA-Ver in the ...
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14 Antitussive Activity of Pseudostellaria heterophylla (Miq.) Pax ...
https://www.mdpi.com/1420-3049/16/4/3360
... exhibited a dose-dependent antitussive effect between 100 to 500 mg/kg. ... But, P. Antitussive and central respiratory depressant effects of Stemona ...
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15 Drugs in Respiratory System - PSPK
https://pspk.fkunissula.ac.id/sites/default/files/Drugs%20in%20Respiratory%20System_modul%20respi%20nov%202017.pdf
Dependent Central Antitussives (Opioid). 2. Independent Central Antitussives (Non. Opioid). B. Peripheral Antitussives. Note : codeine, dextromethorphan and ...
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16 Antitussive Drugs—Past, Present, and Future
https://pharmrev.aspetjournals.org/content/pharmrev/66/2/468.full.pdf?related-urls=yes&legid=pharmrev%3B66/2/468
dependent of their sedative effects and effects on minute ventilation (McLeod et al., 1998). ... central antitussive activity of codeine appears resis-.
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17 Central regulation of the cough reflex: therapeutic implications.
https://europepmc.org/article/pmc/pmc2695989
Also discussed are new insights into cough and NMDA receptor signaling that may lead to the development of more effective antitussive agents with limited side ...
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18 (PDF) Subsensitivity to the cough depressant effects of opioid and ...
https://www.researchgate.net/publication/347035499_Subsensitivity_to_the_cough_depressant_effects_of_opioid_and_non-opioid_antitussives_in_morphine_dependent_rats_relation_to_central_serotonin_function
... published Subsensitivity to the cough depressant effects of opioid and non-opioid antitussives in morphine dependent rats: relation to central serotonin ...
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19 Coughing in Small Animal Patients - Frontiers
https://www.frontiersin.org/articles/10.3389/fvets.2019.00513/full
Antitussives are specifically indicated when a patient has a non-productive cough or chronic cough that interferes with quality of life. Some ...
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20 LATE-BREAKING ABSTRACT - European Respiratory Journal
https://erj.ersjournals.com/content/46/suppl_59/PA3852
In patients treated with ketoprofen lysine salt and a central acting antitussives the median persistence of cough was 11 days, while in the group treated ...
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21 Comparison of the antitussive effects of codeine phosphate 20 ...
https://www.unboundmedicine.com/medline/citation/527635/Comparison_of_the_antitussive_effects_of_codeine_phosphate_20_mg_dextromethorphan_30_mg_and_noscapine_30_mg_using_citric_acid_induced_cough_in_normal_subjects_
› medline › citation
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22 Codeine: A Relook at the Old Antitussive - JAPI
https://www.japi.org/v2b494/codeine-a-relook-at-the-old-antitussive
Codeine is one of the centrally acting narcotic opioids approved for use as an antitussive, a prodrug that is bioactivated by CYP2D6 into morphine in the liver.
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23 Acute Cough—Does Anything Help? - U.S. Pharmacist
https://www.uspharmacist.com/article/acute-coughdoes-anything-help
Takahama K, Shirasaki T. Central and peripheral mechanisms of narcotic antitussives: codeine-sensitive and -resistant coughs. Cough. 2007;3:8.
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24 (codeine) dosing, indications, interactions, adverse effects ...
https://reference.medscape.com/drug/codeine-343310
Antitussives, Narcotic;; Opioid Analgesics.
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25 Codeine and its Alternates for Pain and Cough Relief*
https://apps.who.int/iris/bitstream/handle/10665/266555/PMC2554504.pdf?sequence=1&isAllowed=y
and antitussive properties of codeine and its potential therapeutic alternates. ... dependence and abuse liability on the other, it would appear that the ...
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26 Peripheral and central mechanisms of cough hypersensitivity
https://jtd.amegroups.com/article/view/43624/html
Experiments in laboratory animals have confirmed that cough can be modulated by inhibiting sensory neuron inputs at either of these brainstem sites, dependent ...
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27 Codeine Sulfate - RxList
https://www.rxlist.com/codeine-sulfate-drug.htm
Codeine Sulfate belongs to a class of drugs called Antitussives; Antitussives, ... Infants born to mothers physically dependent on opioids will also be ...
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28 centrally acting antitussive: Topics by Science.gov
https://www.science.gov/topicpages/c/centrally+acting+antitussive
However, the lack of a central action by levodropropizine remains to be fully ... DM did not significantly influence caspase-3-dependent apoptosis.
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29 Effect of Honey, Dextromethorphan, and No Treatment on ...
https://jamanetwork.com/journals/jamapediatrics/fullarticle/571638
Main Outcome Measures Cough frequency, cough severity, bothersome nature of ... EJ Insulin-dependent diabetes mellitus induced by the antitussive agent ...
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30 Codeine for cough or cold in children Art. 31
https://www.ema.europa.eu/en/documents/referral/codeine-article-31-referral-prac-assessment-report_en-0.pdf
central antitussives or no therapy. No information on adverse drug reactions was presented in this publication. There was a double-blind, ...
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31 Current Research & Reviews - MedCrave
https://medcraveonline.com/MOJCRR/MOJCRR-01-00024
Introduction · Central antitussives–Codeine (Opioid) depresses respiratory center, causes dependence, decreases ciliary activity, increases bronchospasm and ...
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32 EP0478778A1 - Antitussive - Google Patents
https://patents.google.com/patent/EP0478778A1/en
Commercially available antitussives which are widely used at present are problematic in that they contain dihydrocodeine which is officially designated as a ...
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33 Endogenous central suppressive mechanisms ... - Monash University
https://research.monash.edu/en/publications/endogenous-central-suppressive-mechanisms-regulating-cough-as-pot
Cough and the accompanying sensation known as the urge-to-cough are complex neurobiological phenomena dependent on sensory and motor neural processing at ...
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34 Antitussives and substance abuse - Semantic Scholar
https://pdfs.semanticscholar.org/75aa/583c63a687ba5ab1ca152885f86ded5c1ffb.pdf
and central catecholamine uptake.27,28 Dextromethorphan also ... addiction to or dependence on other antitussives with high abuse potential.
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35 Bulletin on Narcotics - 1977 Issue 1 - 004 - UNODC
https://www.unodc.org/unodc/en/data-and-analysis/bulletin/bulletin_1977-01-01_1_page005.html
Dependence potential of drotebanol, codeine and thebaine tested in rhesus ... Gross behavioural observation of acute central nervous system ...
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36 5.8 Antitussives – Fundamentals of Nursing Pharmacology
https://opentextbc.ca/nursingpharmacology/chapter/5-8-antitussives/
Dextromethorphan suppresses a cough by depressing the cough center in the medulla oblongata or the cough receptors in the throat, trachea, or lungs, effectively ...
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37 Brain Activity Associated with Placebo Suppression of the ...
https://www.atsjournals.org/doi/10.1164/rccm.201306-1079OC
Rationale: Antitussive therapies are accompanied by a substantial placebo effect, indicating that inhibitory circuits in the brain have a ...
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38 Cough: mechanisms of opioids and the new frontier of chocolate
http://flipper.diff.org/app/items/info/5431
Antitussive treatment using opioids is limited by unacceptable side effects, and there is a great need for more effective remedies.
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39 List of Antitussives - Drugs.com
https://www.drugs.com/drug-class/antitussives.html
› ... › Antitussives
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40 Antitussive Efficacy and Safety Profile of Ethyl Acetate Fraction ...
https://www.hindawi.com/journals/isrn/2013/256934/
by A Wahab · Cited by 11 —
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41 Palliative care: Overview of cough, stridor, and hemoptysis in ...
https://www.uptodate.com/contents/palliative-care-overview-of-cough-stridor-and-hemoptysis-in-adults/print
Interventions depend on the patient's goals of care and include specific ... pharmacologic therapy is cough suppression with antitussives, ...
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42 Antitussive Profile of the NOP Agonist Ro-64-6198 in the ...
https://www.karger.com/Article/Abstract/77448
Although the antitussive action of Ro-64-6198 may be mediated by a central and/or a peripheral site of action, we hypothesize that selective oral NOP agonists ...
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43 delta RECEPTOR - C1351 - Multispan, Inc.
https://multispaninc.com/resources/delta-receptor-c1351/
Dose-dependent stimulation of calcium flux upon treatment with ligand, measured with ... antagonists as a new concept for central acting antitussive drugs.
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44 Antitussives: Introduction, Classifications, MOA ll Easy way ll ...
https://www.youtube.com/watch?v=MqyEO52JSMA
What are Antitussives?Antitussives are medicines that suppress coughing, also known as cough suppressants. Antitussives are thought to work ...
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45 Development of Novel δ Opioid Receptor Inverse Agonists ...
https://pubs.acs.org/doi/10.1021/acschemneuro.9b00368
NTI also exhibited dose-dependent antitussive effects in the cough model induced ... as a New Concept for Central Acting Antitussive Drugs.
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46 Codeine: Time to Say “No” | Pediatrics - AAP Publications
https://publications.aap.org/pediatrics/article/138/4/e20162396/52374/Codeine-Time-to-Say-No
Codeine has been prescribed to pediatric patients for many decades as both an analgesic and an antitussive agent. Codeine is a prodrug with little inherent ...
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47 Codeine - Department Internal medicine
https://www.altmeyers.org/en/internal-medicine/codeine-153906
It has dose-dependent central depressant, analgesic, sedative, sometimes euphoric and above all antitussive effects.
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48 Treatment of chronic cough - Respirologi
http://www.respirologi.com/?page=download.download_process&id=14
Obat penekan atau penghambat batuk; Central antitussive. Dependent. Opioid. Codeine. Independent. Levorphanol drivat: Dextromethorphan; Amido: Pentoxyverine ...
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49 Cough And Cold Combinations (Oral Route) - Mayo Clinic
https://www.mayoclinic.org/drugs-supplements/cough-and-cold-combinations-oral-route/precautions/drg-20061164?p=1
Non-narcotic antitussives ... Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and ...
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50 Chronicles of Pharmaceutical Science - Scientia Ricerca
https://scientiaricerca.com/srcops/pdf/SRCOPS-01-00025.pdf
Risk of opioid dependence, potential ... cough centre in medulla ... Central antitussive agents can be useful in patients with chronic ...
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51 Central and peripheral mechanisms of narcotic antitussives
https://ouci.dntb.gov.ua/en/works/7nE0qXb9/
Abstract Narcotic antitussives such as codeine reveal the antitussive effect primarily via the μ-opioid receptor in the central nervous system (CNS).
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52 Effects of four antitussives on airway neurogenic inflammation ...
https://kd.nsfc.gov.cn/paperDownload/1000006810510.pdf
Keywords Antitussive 4 Neurogenic inflammation 4 ... nals of C-fibers are also the main source of neuropeptides.
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53 Drugs Used in the Management of Respiratory Diseases - VIN
https://www.vin.com/apputil/content/defaultadv1.aspx?pId=11223&id=3858955&print=1
Intracellular effects depend in part on modifications of intracellular levels ... other antitussive agents might act primarily on the peripheral or central ...
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54 Opioid Complications and Side Effects - :::::Pain Physician:::::
https://www.painphysicianjournal.com/current/pdf?article=OTg1&journal=42
Physical dependence and addiction are clinical concerns that may prevent proper prescribing and in ... mechanism by which central opioid receptors mediate.
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55 Definition > Opiate antitussive - Futura-Sciences
http://www.futura-sciences.us/dico/d/medical-science-opiate-antitussive-50006429/
The opiate antitussives such as codeine, pholcodine, and dextromethorphan act by inhibiting the nerve centres in the brain. They are used for dry coughs ...
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56 Pholcodine - Wikipedia
https://en.wikipedia.org/wiki/Pholcodine
Pholcodine is a drug which is an opioid cough suppressant (antitussive). It helps suppress unproductive coughs and also has a mild sedative effect, ...
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57 A Physiological Model of the Human Cough Reflex
https://usir.salford.ac.uk/14670/1/238774.pdf
branches to the central cough centre located in the medulla. The efferent ... suggests that antitussive activity may be stimulus dependent and may.
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58 Drug Scheduling - DEA.gov
https://www.dea.gov/drug-information/drug-scheduling
... the drug's acceptable medical use and the drug's abuse or dependency potential. ... Schedule V drugs are generally used for antidiarrheal, antitussive, ...
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59 Cough (pediatrics) - WikiLectures
https://www.wikilectures.eu/w/Cough_(pediatrics)
central antitussives: codeine, dihydrocodeine, ethylmorphine and ... suppress the respiratory center and does not lead to drug dependence ...
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60 Cough mixtures: not always for cough - RACGP
https://www.racgp.org.au/getattachment/21803014-a610-4879-bf97-95bd8f8d4609/20040510sim.pdf
codeine phosphate (an opioid with central ... Antihistamines are included in some mixtures ... weeks, and whom he believes to be opioid dependent.
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61 Synthesis and antitussive evaluation of verticinone-cholic acid ...
http://www.chinaphar.com/article/download/5870/6542
Aim: To seek a novel and potent antitussive drug based on Shedan–Chuanbei ... the peripheral (modulated by ATP-sensitive K+ channels) and central mechanisms.
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62 Drugs to suppress cough - Taylor and Francis
https://www.tandfonline.com/doi/abs/10.1517/13543784.14.1.19
The most effective indirect antitussives are opioids such as morphine, codeine or pholcodeine, but they produce side effects such as drowsiness, ...
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63 Antitussives Nursing Considerations - NurseStudy.Net
https://nursestudy.net/antitussives-nursing-considerations/
It acts on the cough center of the brain, located in the medulla oblongata of the brainstem, which in turn weakens the cough reflex and elevates the coughing ...
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64 Is opiate action in cough due to sedation? - SAGE Journals
https://journals.sagepub.com/doi/pdf/10.1177/2040622314543220
If sedation was the main antitussive mechanism of these agents, then those reporting sedation would be also those with the greatest antitussive response. There ...
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65 Antitussive Effects of FP01 Lozenges in Subjects With Cough Due to ...
https://www.cochranelibrary.com/content?templateType=related&urlTitle=/central/doi/10.1002/central/CN-01503418&doi=10.1002/central/CN-01503418&p_p_id=scolariscontentdisplay_WAR_scolariscontentdisplay&_scolariscontentdisplay_WAR_scolariscontentdisplay_action=related-content&p_p_lifecycle=0&p_p_mode=view&type=central&contentLanguage=
Effects of Su-Huang Antitussive Capsule on Cough Variant Asthma ... https://clinicaltrials.gov/show/NCT03738917, 2018 | added to CENTRAL: 28 February 2019 ...
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66 Antitussive activity of Adhatoda schimperiana (Hochst.) Nees ...
http://www.ijpsr.info/docs/IJPSR20-11-11-009.pdf
dependent increase in the latent period of cough (P < 0.05), and reduction ... sensory nerve fibers that are broadly divided into three main.
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67 Endogenous central suppressive mechanisms ... - UQ eSpace
https://espace.library.uq.edu.au/view/UQ:352881
Cough and the accompanying sensation known as the urge-to-cough are complex neurobiological phenomena dependent on sensory and motor neural processing at ...
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68 Clinical characteristics and drug utilisation patterns in patients ...
https://www.researchsquare.com/article/rs-1391241/v1.pdf
Keywords: Cough, chronic cough, central antitussives, cough-variant asthma, atopic cough, allergic rhinitis, nasal in ammation, asthma, GERD.
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69 How Does Omalizumab Affect Antitussive Use in Patients With ...
https://www.pulmonologyadvisor.com/home/meetings/ats-2022/omalizumab-and-antitussives-in-allergic-asthma/
Antitussives included over-the-counter or prescription medications that were narcotics or non-narcotics primarily indicated for cough symptom ...
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70 Cough.pdf - Canadian Thoracic Society
https://cts-sct.ca/wp-content/uploads/2018/03/Cough.pdf
Cough secondary to tobacco dependence is often considered normal for smokers. ... Treatment of the cause – smoking cessation – non-specific antitussives if ...
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71 InpharmD™
https://inpharmd.com/inquiries/647d7f7783bc88792ee4941972ff95af4f993d3e30b5b8c93f0d4482031ae2d1
... associated risks with opioid use including dependence, abuse, and central ... recommended codeine along with other opioid-derived antitussives based on ...
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72 Effect of Guaifenesin on Cough Reflex Sensitivity
https://lilimag.net/wp-content/uploads/2021/05/guaifenesin-pdf.pdf
Possible mechanisms include a central antitussive effect, or a peripheral effect by increased ... induce cough in a reproducible and dose-dependent.
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73 Prof. Dr. Esin AKI-YALÇIN
https://acikders.ankara.edu.tr/mod/resource/view.php?id=84678
Antitussives; they reduce the intensity and frequency by suppressing the ... Central effect: Inhibition of cough center ... dependence and toxic effects.
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74 Antitussive effects of the peripherally restricted GABAB ... - Gale
https://link.gale.com/apps/doc/A534306750/HRCA?u=googlescholar&sid=googleScholar&xid=9e748e98
Like 3-APPiA, lesogaberan is inactivated centrally by GAT-dependent transport [25]. ... Influence of central antitussive drugs on the cough motor pattern.
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75 Treatment of Cough
https://www.msc-mu.com/file_download?id=3344
Central Antitussives. Block medullary cough center; These are opioid agents, such as codeine & methadone that are very effective & part of their antitussive ...
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76 Anti Tussives, Mucolytics and Mucokinetics - howMed
http://howmed.net/pharmacology/anti-tussives-mucolytics-and-mucokinetics/
Dextromethorphan: · A synthetic compound · The d-isomer has selective antitussive action (raises threshold for cough & depresses cough center in ...
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77 Upper Respiratory Tract Infection-Associated Acute Cough ...
https://www.liebertpub.com/doi/10.1089/ped.2019.1135
Both swallowing and coughing are motor actions that depend upon sensory ... Peripheral and central antitussive agents could be useful in ...
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78 Expectorant and antitussives - SlideShare
https://www.slideshare.net/SnehalChakorkar/expectorant-and-antitussives
It depresses cough but has no narcotic, analgesic or dependence inducing properties. It is nearly equipotent antitussive as codeine, especially useful in ...
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79 Developing antitussives: The ideal clinical trial
https://hal.archives-ouvertes.fr/hal-00516731/document
should be the main clinical problem. In the past, antitussive drugs have often been tested in patients with COPD and asthma or healthy ...
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80 DXM Addiction, Effects, and Rehab Treatment
https://americanaddictioncenters.org/dextromethorphan-dxm/abuse
Dextromethorphan, commonly referred to as DXM, is a cough suppressant found in more than 120 over-the-counter cold medications.1,2 Typically ...
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81 The German Project of Heroin Assisted Treatment of Opiate ...
https://clinicaltrials.gov/ct2/show/NCT00268814
Current main diagnosis of opiate dependency according to the ICD-10 criteria; Current daily and predominantly intravenous heroin consumption or continuing ...
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82 Opioid Activation of Toll-Like Receptor 4 Contributes to Drug ...
https://www.jneurosci.org/content/jneuro/32/33/11187.full.pdf
the TLR4-dependent central neuroexcit- atory immune signaling, which has been demonstrated to oppose opioid analgesia, should lead to an acute potentiation ...
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83 総説 1= Synaptic transmission in the nucleus tractus solitarius ...
https://www.slib.agu.ac.jp/gakukaisi/pdf/y10_01.pdf
It has been presumed that central antitussives exert their action by inhibiting the so-called 'cough ... terminal via activation of voltage-dependent Ca2+.
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84 Antitussive effects of the peripherally restricted ... - Springer Medizin
https://www.springermedizin.de/antitussive-effects-of-the-peripherally-restricted-gabab-recepto/9623304
GABA and analogs of GABA are subject to uptake in the central nervous system by the ... Like 3-APPiA, lesogaberan is inactivated centrally by GAT-dependent ...
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85 Antitussives drugs cough - Medical encyclopedia
http://medicalency.com/protivokashlevye-sredstva.htm
Antitussives have a weak analgesic properties. The ability to produce drug dependency are considerably smaller than those of narcotic analgesics.
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86 Anaphylaxis caused by tipepidine hibenzate, a central antitussive ...
https://docksci.com/anaphylaxis-caused-by-tipepidine-hibenzate-a-central-antitussive-drug_5a58f311d64ab277310a5eeb.html
Tipepidine hibenzate, a central antitussive drug, is widely used in the management of cough and is generally safe and we...
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87 Narcotic antitussives - definition of narcotic antitussives by The Free ...
https://www.thefreedictionary.com/narcotic+antitussives
1. A substance that affects the central nervous system and is often addictive: drug, hallucinogen, opiate. Informal: dope. 2. Something that induces sleep or ...
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88 5.8 Antitussives – Nursing Pharmacology
https://wtcs.pressbooks.pub/pharmacology/chapter/5-8-antitussives/
Dextromethorphan is an example of an antitussive (see Figure 5.10). ... Dextromethorphan suppresses a cough by depressing the cough center in the medulla ...
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89 Coughing Up White Mucus: Causes and Treatment - Healthline
https://www.healthline.com/health/coughing-up-white-mucus
antitussives such as dextromethorphan (Triaminic Cold and Cough, Robitussin Cough). Consult with your doctor — especially if your symptoms ...
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90 Tecumseh engine repair - Savemi Costruzioni
https://savemicostruzioni.it/tecumseh-engine-repair.html
Series 8 comes with both mounted as well as main idle circuit. ... from tongue-tied or observed antitussives in a tecumseh engines repair manual, ...
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91 E6 white pill
https://associazionedynamica.it/e6-white-pill.html
Does not cause dependence and is readily available at a low cost. ... Hydrocodone bitartrate is an opioid analgesic and antitussive and ...
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