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1 Angioedema (SMQ) - Classes - NCBO BioPortal
https://bioportal.bioontology.org/ontologies/MEDDRA?p=classes&conceptid=20000024
Preferred Name. Angioedema (SMQ). Definitions. Urticaria: o Many possible causes o Characterized by multiple transient wheals, usually with ...
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2 Introductory Guide for Standardised MedDRA Queries (SMQs ...
https://admin.meddra.org/sites/default/files/guidance/file/smq_intguide_20_0_english.pdf
Angioedema (SMQ) has narrow and broad search terms. The detailed notes are documented in section 1.5.2.1. 2.7.4 List of References for Angioedema (SMQ).
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3 Angioedema Caused by Drugs That Prevent the ... - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658484/
For each RASi, the angioedema cases were extracted by application of the standardized MedDRA Query (SMQ) "angioedema (narrow)" [45]. A SMQ is a ...
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4 PT: preferred term. - MDPI
https://mdpi-res.com/d_attachment/jcm/jcm-10-05507/article_deploy/jcm-10-05507-s001.zip?version=1637831081
angioedema (SMQ: 20000024). Narrow scope terms. Broad scope terms code. PT code. PT. 10081035. Acquired C1 inhibitor deficiency. 10003800.
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5 2021 09 15 MedDRA Tools Demonstration: SMQ Analysis Tool
https://www.youtube.com/watch?v=6i3KnBw4Uqo
Sep 16, 2021
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6 Emgality, INN-galcanezumab - European Medicines Agency |
https://www.ema.europa.eu/en/documents/scientific-conclusion/emgality-h-c-psusa-00010733-201903-epar-scientific-conclusions-grounds-variation-terms-marketing_en.pdf
serious, 4 non-serious) qualified under the anaphylactic reaction SMQ, 40 cases qualified under the angioedema SMQ (narrow) and 36 cases described as rash.
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7 Erratum
https://www.tandfonline.com/doi/pdf/10.1517/14740338.2013.849364?needAccess=true
Angioedema (SMQ) narrow. Allergic conditions (HLGT) ... Embolic and thrombotic events, arterial (SMQ) ... Severe cutaneous adverse reactions (SMQ) narrow.
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8 The Utilization of Standardised MedDRA Queries in Marketing ...
https://www.jhsph.edu/research/centers-and-institutes/center-of-excellence-in-regulatory-science-and-innovation/training/Chang_CERSI%20Writing%20Competition_2016.pdf
SMQ Hepatic disorders. (searched in 6 out of 9. (67%) applications). SMQs Anaphylactic reaction, Angioedema,. Central nervous system.
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9 Exploitation of semantic methods to cluster pharmacovigilance ...
https://jbiomedsem.biomedcentral.com/articles/10.1186/2041-1480-5-18
For instance, the Angioedema SMQ contains terms from the Immune system disorders SOC (Systemic allergic reaction, Allergic oedema, ...
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10 1 Appendix 2 MedDRA search criteria for identified risk
https://www.aaojournal.org/cms/10.1016/j.ophtha.2012.07.026/attachment/e4dc144e-d856-4f1c-a7dd-2b0bb1a01ae0/mmc9.pdf
SMQs narrow: “anaphylactic reaction”, “angioedema”, “severe cutaneous ... SMQ: “embolic and thrombotic events, venous” excluding the following.
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11 Pharmacovigilance study of the association between ... - Nature
https://www.nature.com/articles/s41598-022-17366-x
We defined the adverse event by the narrow scope of angioedema (coded SMQ 20000024) with 46 PTs in MedDRA v24.0.
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12 Orencia Safety Signal Workup Review - FDA
https://www.fda.gov/media/142070/download
pediatric case of angioedema with Orencia (abatacept). ... (version 22.0) SMQ Angioedema (narrow) from their Corporate safety database ...
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13 Lessons learnt from Influenza A(H1N1) vaccines benefit-risk ...
https://www.encepp.eu/documents/publications/5_H1N1%20-%20Xavier.pdf
Anaphylactic reaction (narrow SMQ). 329. 54. - anaphylactic shock. 45. 10. - anaphylactoid shock. 1. 0. Angioedema (narrow SMQ).
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14 CIOMS-MedDRA-RedBook-SECURED.pdf
https://cioms.ch/sd7fdh93gewd882ds/78yudej8fddqd6s-red-book/CIOMS-MedDRA-RedBook-SECURED.pdf
the CIOMS SMQ Core Group during the earlier stages, as well as the generous ... changed category from C (Angioedema/Urticaria/Pruritus/Flush) to B (Upper ...
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15 TRIAL STATISTICAL ANALYSIS PLAN
https://clinicaltrials.gov/ProvidedDocs/21/NCT04086121/SAP_001.pdf
SMQ. Standardised MedDRA query. SOC. System Organ Class ... Angioedema, Hypersensitivity). Anaphylactic reaction. Narrow SMQ “Anaphylactic ...
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16 Safety and Usage of C1-Inhibitor in Hereditary Angioedema
https://www.jaci-inpractice.org/article/S2213-2198(16)30128-3/pdf
Angioedema: Berinert Registry Data ... documented in studies in patients with hereditary angioedema ... SMQ- Standardized MedDRA Queries.
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17 Severe cutaneous adverse reactions associated with systemic ...
https://onlinelibrary.wiley.com/doi/10.1111/1346-8138.16398
... were defined according to the Standardized MedDRA Query (SMQ). ... DRESS; 4 (16), Angioedema; 11 (13.6), Nausea/vomiting; 21 (5.1).
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18 Safety and Usage of C1-Inhibitor in Hereditary Angioedema
https://www.sciencedirect.com/science/article/pii/S2213219816301283
Plasma-derived, highly purified, pasteurized, nanofiltered C1-inhibitor concentrate. SAEs. Serious adverse events. SMQ. Standardized MedDRA Queries.
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19 Angioedema Information | Mount Sinai - New York
https://www.mountsinai.org/health-library/diseases-conditions/angioedema
Angioneurotic edema; Welts; Allergic reaction - angioedema; Hives - angioedema. Share. Angioedema is swelling that is similar to hives, but the swelling is ...
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20 A Method for Retrieval of Adverse Event Terms in Clinical Trial ...
https://europepmc.org/article/med/27274655
The SMQ Severe cutaneous adverse reactions was used as a probe in a mock AE ... of a JMP data table and labeled appropriately [e.g. Angioedema (SMQ) PTs].
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21 Adverse Event of Special Interest (AESI), Standardized ...
http://onbiostatistics.blogspot.com/2015/02/adverse-event-of-special-interest-aesi.html
... were identified by utilizing the broad Anaphylactic Reaction algorithmic Standardized MedDRA query (SMQ) and the broad Angioedema SMQ, ...
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22 Safety Data Analysis and SMQs - MedDRA
https://admin.ich.org/sites/default/files/inline-files/Safety_Data_Analysis_and_SMQs_JHarrison.pdf
Narrow in Acute renal failure (SMQ). • Broad in Rhabdomyolysis/myopathy (SMQ). 19. © 2009 Northrop Grumman Corporation. ... Angioedema. Blood pressure.
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23 Standardised MedDRA Queries (SMQs): Beyond the Basics
https://www.lexjansen.com/pharmasug/2022/DS/PharmaSUG-2022-DS-112.pdf
One item to note in using the SMQ scope search is that using a “broad” search of terms ... more broad-based or inclusive SMQ. ... ABC-001-001 Angioedema.
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24 smq-and-cq.pdf - DataRich Consulting
https://datarichconsulting.com/assets/smq-and-cq.pdf
› assets › smq-and-cq
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25 Angioedema Caused by Drugs That Prevent the Degradation ...
https://www.researchgate.net/publication/356681423_Angioedema_Caused_by_Drugs_That_Prevent_the_Degradation_of_Vasoactive_Peptides_A_Pharmacovigilance_Database_Study
PDF | Angioedema results from the decreased degradation of vasoactive ... When creating the database for analysis, PT and SMQ were linked.
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26 Hypersensitivity Reactions in Patients With Atopic Dermatitis
https://www.lillymedical.eu/en-gb/answers/olumiant-baricitinib-hypersensitivity-reactions-in-patients-with-atopic-dermatitis-134745
... see Standardized MedDRA Hypersensitivity Query (SMQ) Preferred Terms); angioedema SMQ (broad and narrow; see Standardized MedDRA Angioedema Query (SMQ) ...
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27 Clinical Trial Protocol: DX-2930-03 - AMA Ed Hub
https://edhub.ama-assn.org/data/journals/jama/937658/joi180130supp1_prod.pdf
hereditary angioedema attacks: a randomized clinical trial. ... Summary tables with SOCs and PTs, from the SMQ searches, will be generated.
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28 EMDAC Briefing Document
https://pink.pharmaintelligence.informa.com/-/media/pmbi-old-site/supporting-documents/the-pink-sheet-daily/2015/april/alogliptin_ac_fda_brfg.pdf
Hepatic Disorders SMQ by Preferred Term Reported in ≥2 Subjects in either. Treatment Group . ... Angioedema SMQ Adverse Events .
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29 MedDRA Data Retrieval and Presentation: Points to Consider
http://mssotools.com/MSSOWeb/PTC/drp_ptc_r33.html
Algorithmic SMQ (SMQ Anaphylactic reaction)*. Category B – Upper airway/Respiratory, Category C – Angioedema/Urticaria, etc. Category D – Cardiovascular/ ...
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30 safety of inhaled glycopyrronium in patients with COPD - CORE
https://core.ac.uk/download/pdf/34655360.pdf
Notes: CCV condition determined based on the following predefined SMQ search criteria: angioedema (narrow scope); Cerebrovascular disorders (narrow); ...
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31 Semantic distance and terminology structuring methods for the ...
https://aclanthology.org/W12-2403.pdf
for the SMQ Angioedema), but also the SMQs may contain non relevant terms or may miss relevant terms (thus, Testicular oedema, ...
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32 How serious are cardiovascular complications following the ...
https://www.aretezoe.com/how-serious-were-the-reported-cases-of-myocarditis-pericarditis-in-12-to-17-year-old-males-associated-with-the-pfizer-biontech-covid19-vaccine
Angioedema (SMQ), 14. Supraventricular tachyarrhythmias (SMQ), 14. Biliary system related investigations, signs and symptoms (SMQ), 13 ...
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33 Safety of inhaled glycopyrronium in patients with COPD
https://www.dovepress.com/safety-of-inhaled-glycopyrronium-in-patients-with-copd-a-comprehensive-peer-reviewed-fulltext-article-COPD
Notes: CCV condition determined based on the following predefined SMQ search criteria: Angioedema (narrow scope); Cerebrovascular disorders ...
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34 Supplementary appendix - The Lancet
https://www.thelancet.com/cms/10.1016/S1474-4422(20)30279-9/attachment/358b6a3a-3fdf-48d0-9a2f-8063cb7e0d3a/mmc1.pdf
Angioedema SMQ. 1 (0·4%). 0 (0%). Urticaria. 1 (0·4%). 0 (0%). Abbreviations: SMQ=standardised MedDRA queries. MedDRA=Medical Dictionary for Regulatory ...
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35 A15-60 - Sacubitril/valsartan - Extract of dossier assessment
https://www.iqwig.de/download/a15-60_sacubitril-valsartan_extract-of-dossier-assessment.pdf
Angioedema. Angioedemai. 4203. 19 (0.45). 4229. 10 (0.24). 1.88 [0.90; 3.89]c, d; p = 0.097e. SMQ angioedema. 4203. 300 (7.14).
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36 CDR Clinical Review Report for Takhzyro - CADTH
https://www.cadth.ca/sites/default/files/cdr/clinical/sr0618-takhzyro-clinical-review-report.pdf
Table 18: Severity of Hereditary Angioedema Attacks (Intention-to-Treat ... the HELP-03 study (based on Standardised MedDRA Query [SMQ]-defined events). The.
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37 PC 56 to 63.pdf - DPBH
https://dpbh.nv.gov/uploadedFiles/dpbhnvgov/content/Boards/BOH/Meetings/2022/PC%2056%20to%2063.pdf
the Anaphylactic reaction SMQ (Narrow and Broad) search strategy, ... shock;Anaphylactoid syndrome of pregnancy;Angioedema;Angiopathic.
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38 Medical Informatics in a United and Healthy Europe: ...
https://books.google.com/books?id=dxfvAgAAQBAJ&pg=PA525&lpg=PA525&dq=angioedema+smq&source=bl&ots=a9wiPcKEW4&sig=ACfU3U3c8bjU3Uwob_Sxwi3qxDdBT7-2dQ&hl=en&sa=X&ved=2ahUKEwi_3q2No9r7AhVMkIkEHS6wBAgQ6AF6BQiwARAD
For example, in the SMQ « angioedema », the term W :OEDEMA_CIRCUMORAL does not exist while it should. b0. There is a taxonomic error in the ontology.
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39 Cumulative clinical experience with MF59-adjuvanted trivalent ...
https://www.ijidonline.com/article/S1201-9712(19)30149-3/pdf
(SMQ) agreed upon with the Food and Drug Administration (FDA). ... per 100,000 doses sold), angioedema (0.07), Guillain–Barré.
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40 Ligelizumab is well tolerated and exhibits a safety profile ...
https://www.urticariaknowledgecenter.novartis.com/PAAM/presentations/2019/PAAM2019_LigelizumabisWellTolerated.pdf
(hives), angioedema, or both for 6 weeks or more in the absence of specific ... HLT, High level term; PT, Preferred term; SMQ, Standardised MedDRA quieries.
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41 Long-term safety of rituximab in rheumatoid arthritis
https://ard.bmj.com/content/72/9/1496
... malignant or unspecified tumours standard MedDRA query (SMQ)), were medically ... or anaphylactoid reactions, drug hypersensitivity and angioedema.
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42 Response to Heparin Contamination Helped Protect Public ...
https://www.gao.gov/assets/a311883.html
Scope/category: SMQ Broad Skin PTs; Anaphylactic reaction SMQ+ and non-SMQ preferred terms: Preferred term: Allergic oedema, angioedema, erythema, ...
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43 Analyses of Ocular Adverse Reactions Associated With ...
https://ar.iiarjournals.org/content/42/9/4439
The eight OARs were as follows: periorbital and eyelid disorders (SMQ 2000179), ... Angioedema caused by drugs that prevent the degradation of vasoactive ...
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44 Adjuvant T-DM1 versus trastuzumab in patients with residual ...
https://www.annalsofoncology.org/article/S0923-7534(21)01168-6/pdf
Thrombocytopenia: SMQ (narrow) 'hematopoietic thrombocytopenia'. ... IRR/hypersensitivity (type 1): SMQs of anaphylaxis and angioedema, ...
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45 Angioedema - Allergy & Immunology - UCLA Health
https://www.uclahealth.org/medical-services/allergy/disorders-treated/angioedema
Angioedema is swelling of the skin and underlying tissue. It is most noticeable around the eyes, lips, hands, and feet, though it may affect other areas ...
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46 Standardized MedDRA Queries Distribution - JMP
https://www.jmp.com/support/downloads/JMPC80_documentation/Content/JMPCUserGuide/OP_C_EV_0014.htm
The bars display the frequency or percentage by treatment of subjects that meet the criteria for each SMQ. For non-hierarchical SMQs, the results of individual ...
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47 Angioedema - Knowledge @ AMBOSS
https://www.amboss.com/us/knowledge/Angioedema/
Angioedema is a self-limited, localized swelling of the dermis, subcutaneous tissues, and/or submucosal tissues caused by fluid leakage into ...
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48 Evaluation and Management of Angioedema in the ...
https://westjem.com/articles/evaluation-and-management-of-angioedema-in-the-emergency-department.html
Histamine-mediated angioedema should be treated with epinephrine ... Angioedema accounts for 80,000 to 112,000 emergency department (ED) ...
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49 Angioedema - Wikipedia
https://en.wikipedia.org/wiki/Angioedema
Angioedema is an area of swelling (edema) of the lower layer of skin and tissue just under the skin or mucous membranes. The swelling may occur in the face, ...
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50 Angioedema - wikidoc
https://www.wikidoc.org/index.php/Angioedema
Angioedema can be classified into the following types: Allergic angioedema, bradykinin mediated angioedema, drug induced angioedema, hereditary ...
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51 Clinical Practice Guideline: Initial Evaluation and ...
https://www.aaem.org/resources/statements/position/clinical-practice-guideline-initial-evaluation-and-management-of-patients-presenting-with-acute-urticaria-or-angioedema
Key words consisted of urticaria, angioedema, angio-neurotic edema, antihistamines, corticosteroids, nasopharyngolaryngoscopy, angiotensin converting enzyme ...
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52 Food and Drug Administration (FDA): Response to Heparin ...
https://books.google.com/books?id=LRiJCVMx6ngC&pg=PA48&lpg=PA48&dq=angioedema+smq&source=bl&ots=gdNDY9zB7u&sig=ACfU3U0dX34RUcwwoqpeMzQ64w5YC4v9lg&hl=en&sa=X&ved=2ahUKEwi_3q2No9r7AhVMkIkEHS6wBAgQ6AF6BQivARAD
... SMQ+ and non-SMQ preferred terms Scope/category Preferred term SMQ narrow ... wheezing SMQ Broad Allergic oedema, angioedema, erythema, eye oedema, ...
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53 Recent Advances in Management of Heart Failure, An Issue of ...
https://books.google.com/books?id=2tpwDwAAQBAJ&pg=PA490&lpg=PA490&dq=angioedema+smq&source=bl&ots=FS2qBJAT5u&sig=ACfU3U12OQhw207akhGJvPjL9FbiE94Cmw&hl=en&sa=X&ved=2ahUKEwi_3q2No9r7AhVMkIkEHS6wBAgQ6AF6BQiuARAD
Table 4 Dementia Dementia/Cognition-Related Adverse Events (MedRA) SMQ ... ARNI should not be administered to patients with a history of angioedema.
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