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Google Keyword Rankings for : mitochondria female infertility
1
The role of mitochondrial activity in female fertility and assisted ...
https://pubmed.ncbi.nlm.nih.gov/29598846/
Mitochondria have been implicated as key factors regulating female reproductive processes. Notable progress has been made in determining the role of ...
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https://pubmed.ncbi.nlm.nih.gov/29598846/
Mitochondria have been implicated as key factors regulating female reproductive processes. Notable progress has been made in determining the role of ...
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2
The impact of mitochondrial function/dysfunction on IVF and ...
https://rbej.biomedcentral.com/articles/10.1186/1477-7827-12-111
Mitochondria play vital roles in oocyte functions and they are critical indicators of oocyte quality which is important for fertilization ...
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https://rbej.biomedcentral.com/articles/10.1186/1477-7827-12-111
Mitochondria play vital roles in oocyte functions and they are critical indicators of oocyte quality which is important for fertilization ...
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3
Mitochondria as a biomarker for IVF outcome in - Reproduction
https://rep.bioscientifica.com/view/journals/rep/157/6/REP-18-0580.xml
Some studies have linked increased levels of mitochondrial DNA to aneuploidy, advanced maternal age and euploid blastocyst with implantation failure, while ...
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https://rep.bioscientifica.com/view/journals/rep/157/6/REP-18-0580.xml
Some studies have linked increased levels of mitochondrial DNA to aneuploidy, advanced maternal age and euploid blastocyst with implantation failure, while ...
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4
Ovarian ageing: the role of mitochondria in oocytes and follicles
https://academic.oup.com/humupd/article/22/6/725/2420603
Mitochondria, which are major factors of oocyte quality, may be directly impacted during ovarian ageing (Table I).
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https://academic.oup.com/humupd/article/22/6/725/2420603
Mitochondria, which are major factors of oocyte quality, may be directly impacted during ovarian ageing (Table I).
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5
Potential of Mitochondrial Genome Editing for Human Fertility ...
https://www.frontiersin.org/articles/10.3389/fgene.2021.673951/full
mtDNA in Female Infertility. Sufficient energy supply is essential for satisfactory oocyte quality, which enables a positive reproductive result. It has long ...
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https://www.frontiersin.org/articles/10.3389/fgene.2021.673951/full
mtDNA in Female Infertility. Sufficient energy supply is essential for satisfactory oocyte quality, which enables a positive reproductive result. It has long ...
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6
The role of mitochondria in the female ... - Wiley Online Library
https://onlinelibrary.wiley.com/doi/full/10.1002/cbin.10947
Importantly, oocyte mitochondria accumulate errors and become dysfunctional with aging, likely leading to infertility in women of advanced age.
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https://onlinelibrary.wiley.com/doi/full/10.1002/cbin.10947
Importantly, oocyte mitochondria accumulate errors and become dysfunctional with aging, likely leading to infertility in women of advanced age.
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7
Is age-related decline in female fertility a mitochondrial ...
https://medcraveonline.com/OGIJ/is-age-related-decline-in-female-fertility-a-mitochondrial-dysfunction.html
As normal mitochondrial function is essential for embryonic development, dysfunction of the oocyte mitochondria may be responsible for the age- ...
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https://medcraveonline.com/OGIJ/is-age-related-decline-in-female-fertility-a-mitochondrial-dysfunction.html
As normal mitochondrial function is essential for embryonic development, dysfunction of the oocyte mitochondria may be responsible for the age- ...
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8
The Role of Mitochondria in Human Fertility and Early Embryo ...
https://www.mdpi.com/2073-4409/11/5/797
Mitochondria are well known as 'the powerhouses of the cell'. Indeed, their major role is cellular energy production driven by both mitochondrial and ...
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https://www.mdpi.com/2073-4409/11/5/797
Mitochondria are well known as 'the powerhouses of the cell'. Indeed, their major role is cellular energy production driven by both mitochondrial and ...
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9
The use of mitochondrial nutrients to improve the outcome of ...
https://www.fertstert.org/article/S0015-0282(09)02484-4/abstract
As women and oocytes age and oocyte mitochondrial energy production ... of this hypothesis in older women undergoing fertility treatments.
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https://www.fertstert.org/article/S0015-0282(09)02484-4/abstract
As women and oocytes age and oocyte mitochondrial energy production ... of this hypothesis in older women undergoing fertility treatments.
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10
Mitochondrial enrichment in infertile patients - SAGE Journals
https://journals.sagepub.com/doi/full/10.1177/26334941211023544
By taking into account the close relation between mitochondrial function/quantity and oocyte/embryo quality, mtDNA has been proposed as a potential biomarker ...
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https://journals.sagepub.com/doi/full/10.1177/26334941211023544
By taking into account the close relation between mitochondrial function/quantity and oocyte/embryo quality, mtDNA has been proposed as a potential biomarker ...
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11
The Role of Mitochondria from Mature Oocyte to ... - Hindawi
https://www.hindawi.com/journals/ogi/2013/183024/
Supplementation of mitochondrial activity in oocytes by transfer of cytoplasm or mitochondria improves fertility in all species tested including humans.
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https://www.hindawi.com/journals/ogi/2013/183024/
Supplementation of mitochondrial activity in oocytes by transfer of cytoplasm or mitochondria improves fertility in all species tested including humans.
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12
Energizing eggs with healthy mitochondria: A dream or a reality?
https://www.ivi-rmainnovation.com/energizing-eggs-with-healthy-mitochondria-dream-or-reality/
Female fertility is one of the first physiological functions adversely affected by aging. One important factor is the mitochondrial ...
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https://www.ivi-rmainnovation.com/energizing-eggs-with-healthy-mitochondria-dream-or-reality/
Female fertility is one of the first physiological functions adversely affected by aging. One important factor is the mitochondrial ...
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13
Fertility In Women Over 35: Nutrients For Your Mitochondria
https://guerguerian-rose.medium.com/fertility-in-women-over-35-nutrients-for-your-mitochondria-a959fdfb68cc?source=---------4----------------------------
Infertility affects many women, particularly over the age of 35. Doctors blame poor egg quality and quantity, and researchers feel that the mitochondria ...
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https://guerguerian-rose.medium.com/fertility-in-women-over-35-nutrients-for-your-mitochondria-a959fdfb68cc?source=---------4----------------------------
Infertility affects many women, particularly over the age of 35. Doctors blame poor egg quality and quantity, and researchers feel that the mitochondria ...
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14
Female fertility: The role of mitochondrial protease LONP1 in ...
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00065-2/fulltext
In human, the number of mitochondria increases from dozens to more than 100,000 during the oocyte maturation, which determines the quality of ...
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https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00065-2/fulltext
In human, the number of mitochondria increases from dozens to more than 100,000 during the oocyte maturation, which determines the quality of ...
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15
CoQ10-Mitochondrial Energizer in Ageing Oocytes and ...
https://www.jsafog.com/doi/JSAFOG/pdf/10.5005/jp-journals-10006-1429
Female infertility is one of the first physiological functions adversely affected by aging. Fecundity of the female starts declining at age of 32 and decreases ...
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https://www.jsafog.com/doi/JSAFOG/pdf/10.5005/jp-journals-10006-1429
Female infertility is one of the first physiological functions adversely affected by aging. Fecundity of the female starts declining at age of 32 and decreases ...
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16
The Experimental Fertility Treatment Not Allowed in the U.S.
https://time.com/5492640/mitochondrial-replacement-therapy/
The resulting egg, containing the affected woman's DNA and the donor's nonmutated mitochondria, can be fertilized by the father's sperm and ...
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https://time.com/5492640/mitochondrial-replacement-therapy/
The resulting egg, containing the affected woman's DNA and the donor's nonmutated mitochondria, can be fertilized by the father's sperm and ...
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17
Mitofusin 1 is required for female fertility and to maintain ...
https://www.nature.com/articles/s41419-019-1799-3
Mitochondria are dynamic organelles that continually adapt their structure through fusion and fission in response to changes in their ...
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https://www.nature.com/articles/s41419-019-1799-3
Mitochondria are dynamic organelles that continually adapt their structure through fusion and fission in response to changes in their ...
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18
Genetics of Mitochondrial dysfunction and infertility
https://www.research.manchester.ac.uk/portal/files/65057642/Genetics_of_Mitochondrial_dysfunction_and_infertility_.docx
One prominent cause of female infertility is primary ovarian insufficiency (POI), also known as premature ovarian failure, defined as the cessation of the ...
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https://www.research.manchester.ac.uk/portal/files/65057642/Genetics_of_Mitochondrial_dysfunction_and_infertility_.docx
One prominent cause of female infertility is primary ovarian insufficiency (POI), also known as premature ovarian failure, defined as the cessation of the ...
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19
Proponents start push to lift U.S. ban on 'three-parent IVF' - STAT
https://www.statnews.com/2019/04/16/mitochondrial-replacement-three-parent-ivf-ban/
These diseases are inherited from the mother's DNA, so mitochondrial replacement therapy involves taking the nucleus of the mother's egg and ...
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https://www.statnews.com/2019/04/16/mitochondrial-replacement-three-parent-ivf-ban/
These diseases are inherited from the mother's DNA, so mitochondrial replacement therapy involves taking the nucleus of the mother's egg and ...
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20
Female fertility, reproductive ageing, and mitochondrial diseases
https://www.youtube.com/watch?v=66-IvG-dGBI
Aug 6, 2019
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https://www.youtube.com/watch?v=66-IvG-dGBI
Aug 6, 2019
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21
Oocyte mitochondria: role on fertility and disease transmission
https://www.animal-reproduction.org/article/doi/10.21451/1984-3143-AR2018-0069
Oocyte mitochondria are increased in number, smaller, and rounder in appearance than mitochondria in somatic cells. Moreover, mitochondrial numbers and ...
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https://www.animal-reproduction.org/article/doi/10.21451/1984-3143-AR2018-0069
Oocyte mitochondria are increased in number, smaller, and rounder in appearance than mitochondria in somatic cells. Moreover, mitochondrial numbers and ...
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22
Mitochondrial unfolded protein response
https://www.fertstertdialog.com/posts/41586-27277
A number of mouse models with mitochondrial dysfunction result in infertility, further confirming the key role of mitochondria in female ...
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https://www.fertstertdialog.com/posts/41586-27277
A number of mouse models with mitochondrial dysfunction result in infertility, further confirming the key role of mitochondria in female ...
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23
Mitochondrial Replacement in the Clinic | NEJM
https://www.nejm.org/doi/10.1056/NEJMcibr2002015
It is not clear that mitochondrial defects that are seen in the oocytes obtained from older women contribute to a risk of infertility or ...
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https://www.nejm.org/doi/10.1056/NEJMcibr2002015
It is not clear that mitochondrial defects that are seen in the oocytes obtained from older women contribute to a risk of infertility or ...
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24
Mitochondria-related male infertility - PNAS
https://www.pnas.org/doi/10.1073/pnas.0604641103
1). ... Considering that sperm motility depends on mitochondrial respiratory function (7), these findings from human studies predict that the accumulation of ...
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https://www.pnas.org/doi/10.1073/pnas.0604641103
1). ... Considering that sperm motility depends on mitochondrial respiratory function (7), these findings from human studies predict that the accumulation of ...
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25
The role of mitochondria in egg quality and ageing
https://www.dralexpolyakov.com.au/blog/the-role-of-mitochondria-in-egg-quality-and-ageing
Ageing and mitochondrial dysfunction ... The female age is the single biggest factor in determining woman's fertility, due to a decline in the quantity and ...
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https://www.dralexpolyakov.com.au/blog/the-role-of-mitochondria-in-egg-quality-and-ageing
Ageing and mitochondrial dysfunction ... The female age is the single biggest factor in determining woman's fertility, due to a decline in the quantity and ...
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26
Mitochondrial Function and Male Infertility | SpringerLink
https://link.springer.com/chapter/10.1007/978-3-540-48461-5_8
1994). Frank and Hurst (1996) have also hypothesized that a germ-line mutation of the mtDNA with severe effects on males but only mild effects on females might ...
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https://link.springer.com/chapter/10.1007/978-3-540-48461-5_8
1994). Frank and Hurst (1996) have also hypothesized that a germ-line mutation of the mtDNA with severe effects on males but only mild effects on females might ...
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27
U.S. researcher says he's ready to start pregnancies ... - PBS
https://www.pbs.org/newshour/health/u-s-researcher-says-hes-ready-to-start-pregnancies-with-three-parent-embryos
The women are all carriers of genetic disorders that are passed down through maternal mitochondria, the energy-generating organelles inside ...
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https://www.pbs.org/newshour/health/u-s-researcher-says-hes-ready-to-start-pregnancies-with-three-parent-embryos
The women are all carriers of genetic disorders that are passed down through maternal mitochondria, the energy-generating organelles inside ...
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28
The role of mitochondria in the female germline: Implications ...
https://www.researchgate.net/publication/323018223_The_role_of_mitochondria_in_the_female_germline_Implications_to_fertility_and_inheritance_of_mitochondrial_diseases_Role_of_mitochondria_in_the_female_germline
In addition, mitochondria and their own genomes (mitochondrial DNA – mtDNA) may become damaged with time, which might be one reason why aging ...
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https://www.researchgate.net/publication/323018223_The_role_of_mitochondria_in_the_female_germline_Implications_to_fertility_and_inheritance_of_mitochondrial_diseases_Role_of_mitochondria_in_the_female_germline
In addition, mitochondria and their own genomes (mitochondrial DNA – mtDNA) may become damaged with time, which might be one reason why aging ...
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29
Mitochondrial Manipulation Technology in US Soon? Unlikely
https://www.medscape.com/viewarticle/840479
Lawmakers in the United Kingdom voted recently to allow fertility clinics to use mitochondrial manipulation technology (MMT) to enable women ...
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https://www.medscape.com/viewarticle/840479
Lawmakers in the United Kingdom voted recently to allow fertility clinics to use mitochondrial manipulation technology (MMT) to enable women ...
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30
Mitochondrial Reproductive Options - The Lily Foundation
https://www.thelilyfoundation.org.uk/get-informed/mitochondrial-reproductive-options/
Mitochondrial donation is a novel IVF procedure. It uses eggs from both a healthy donor and a woman with mitochondrial disease. The nuclear DNA is removed from ...
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https://www.thelilyfoundation.org.uk/get-informed/mitochondrial-reproductive-options/
Mitochondrial donation is a novel IVF procedure. It uses eggs from both a healthy donor and a woman with mitochondrial disease. The nuclear DNA is removed from ...
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31
Mitochondrial Replacement Therapy Explained - WINFertility
https://www.winfertility.com/blog/mitochondrial-replacement-therapy-explained/
Mitochondrial replacement therapy (MRT) involves using an egg from an egg donor who doesn't have mutations. The nucleus of the egg is removed ...
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https://www.winfertility.com/blog/mitochondrial-replacement-therapy-explained/
Mitochondrial replacement therapy (MRT) involves using an egg from an egg donor who doesn't have mutations. The nucleus of the egg is removed ...
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32
Altered Levels of Mitochondrial DNA Are Associated ... - PLOS
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005241
The quantity of mtDNA was significantly higher in embryos from older women (P=0.003). Additionally, mtDNA levels were elevated in aneuploid ...
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https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005241
The quantity of mtDNA was significantly higher in embryos from older women (P=0.003). Additionally, mtDNA levels were elevated in aneuploid ...
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33
Three-parent baby | Definition, Process, History, & Facts
https://www.britannica.com/science/three-parent-baby
The various approaches could help women overcome infertility and could prevent the transmission to their offspring of potentially debilitating mitochondrial ...
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https://www.britannica.com/science/three-parent-baby
The various approaches could help women overcome infertility and could prevent the transmission to their offspring of potentially debilitating mitochondrial ...
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34
Germline Nuclear Transfer Technology to Overcome ...
https://www.cambridge.org/core/books/manual-of-intracytoplasmic-sperm-injection-in-human-assisted-reproduction/germline-nuclear-transfer-technology-to-overcome-mitochondrial-diseases-and-female-infertility/E260556436874ED3D499D28F704CF624
... Technology to Overcome Mitochondrial Diseases and Female Infertility ... aim to avoid mtDNA diseases or to overcome certain forms of female infertility.
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https://www.cambridge.org/core/books/manual-of-intracytoplasmic-sperm-injection-in-human-assisted-reproduction/germline-nuclear-transfer-technology-to-overcome-mitochondrial-diseases-and-female-infertility/E260556436874ED3D499D28F704CF624
... Technology to Overcome Mitochondrial Diseases and Female Infertility ... aim to avoid mtDNA diseases or to overcome certain forms of female infertility.
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35
The Role of Mitochondria in Oocyte and Early Embryo Health
https://www.lidsen.com/journals/genetics/genetics-03-01-070
The mitochondria of the oocyte are a prominent source of energy metabolism as well as mitochondrial DNA that will later populate the cells of the offspring.
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https://www.lidsen.com/journals/genetics/genetics-03-01-070
The mitochondria of the oocyte are a prominent source of energy metabolism as well as mitochondrial DNA that will later populate the cells of the offspring.
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36
Female Mouse Infertility Remedied by NMN
https://www.nmn.com/news/nmn-remedies-infertility-in-female-mice-with-mitochondrial-mutations
How this happens is that the accumulation of mitochondrial DNA mutations decreases fertility by impairing the oocyte's balance in the levels of ...
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https://www.nmn.com/news/nmn-remedies-infertility-in-female-mice-with-mitochondrial-mutations
How this happens is that the accumulation of mitochondrial DNA mutations decreases fertility by impairing the oocyte's balance in the levels of ...
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37
Mitochondrial Transfer: The making of three-parent babies
https://sitn.hms.harvard.edu/flash/2018/mitochondrial-transfer-making-three-parent-babies/
A man and woman have sex, the male sperm fertilizes the female egg, ... team that uses mitochondrial transfer to treat infertility.
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https://sitn.hms.harvard.edu/flash/2018/mitochondrial-transfer-making-three-parent-babies/
A man and woman have sex, the male sperm fertilizes the female egg, ... team that uses mitochondrial transfer to treat infertility.
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38
The Brave New World of Three-Parent I.V.F.
https://www.nytimes.com/2014/06/29/magazine/the-brave-new-world-of-three-parent-ivf.html
A woman's egg holds hundreds of thousands of mtDNA that are distributed randomly into the cells of a developing embryo. Each cell contains ...
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https://www.nytimes.com/2014/06/29/magazine/the-brave-new-world-of-three-parent-ivf.html
A woman's egg holds hundreds of thousands of mtDNA that are distributed randomly into the cells of a developing embryo. Each cell contains ...
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39
Mitochondria in Ovarian Aging and Reproductive Longevity.
https://europepmc.org/article/med/32896666
Mitochondrial dysfunction is one of the hallmarks of aging. Consistently mitochondrial DNA (mtDNA) copy number and function decline with age in ...
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https://europepmc.org/article/med/32896666
Mitochondrial dysfunction is one of the hallmarks of aging. Consistently mitochondrial DNA (mtDNA) copy number and function decline with age in ...
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40
Research Progress on Mitochondrial Replacement Therapies ...
https://austinpublishinggroup.com/thyroid-research/fulltext/thyroids-v5-id1055.php
Importantly, oocyte mitochondria accumulate errors and become dysfunctional with aging, most likely resulting in infertility in women of advanced age. Therefore ...
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https://austinpublishinggroup.com/thyroid-research/fulltext/thyroids-v5-id1055.php
Importantly, oocyte mitochondria accumulate errors and become dysfunctional with aging, most likely resulting in infertility in women of advanced age. Therefore ...
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41
Incompatibility between Nuclear and Mitochondrial Genomes ...
https://www.cell.com/cell-metabolism/pdfExtended/S1550-4131(16)30298-4
ment of F1 offspring with reduced male fertility but unaffected reproductive fitness in females. Further- more, donor PWD mtDNA was faithfully transmitted.
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https://www.cell.com/cell-metabolism/pdfExtended/S1550-4131(16)30298-4
ment of F1 offspring with reduced male fertility but unaffected reproductive fitness in females. Further- more, donor PWD mtDNA was faithfully transmitted.
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42
A Literature Review on Mitochondrial Dysfunction and “Three ...
https://digitalrepository.salemstate.edu/bitstream/handle/20.500.13013/742/auto_convert.pdf?sequence=2&isAllowed=y
Whether it is from a genetic mutation or a change in mitochondrial ... woman will pass that dysfunctional ... female infertility with mtDNA depletion.
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https://digitalrepository.salemstate.edu/bitstream/handle/20.500.13013/742/auto_convert.pdf?sequence=2&isAllowed=y
Whether it is from a genetic mutation or a change in mitochondrial ... woman will pass that dysfunctional ... female infertility with mtDNA depletion.
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43
Three-Parent IVF Now Legal in Two Countries - WebMD
https://www.webmd.com/infertility-and-reproduction/news/20220506/three-parent-ivf-now-legal-in-two-countries
To avoid children inheriting this damaged genetic material, mitochondrial donation, also known as three-parent in vitro fertilization (IVF), ...
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https://www.webmd.com/infertility-and-reproduction/news/20220506/three-parent-ivf-now-legal-in-two-countries
To avoid children inheriting this damaged genetic material, mitochondrial donation, also known as three-parent in vitro fertilization (IVF), ...
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44
The role of mitochondrial activity in female fertility and assisted ...
https://www.semanticscholar.org/paper/The-role-of-mitochondrial-activity-in-female-and-Cecchino-Seli/1bc9b98a1b6ca099a2acf028b764b1656a730122
Semantic Scholar extracted view of "The role of mitochondrial activity in female fertility and assisted reproductive technologies: overview and current ...
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https://www.semanticscholar.org/paper/The-role-of-mitochondrial-activity-in-female-and-Cecchino-Seli/1bc9b98a1b6ca099a2acf028b764b1656a730122
Semantic Scholar extracted view of "The role of mitochondrial activity in female fertility and assisted reproductive technologies: overview and current ...
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45
Autologous mitochondria transport via transzonal filopodia ...
https://www.biorxiv.org/content/10.1101/2021.10.30.466630v1.full.pdf
Mitochondria transfer can rescue oocyte aging-related infertility. However, heterologous ... When the female aged, its UC-MSCs were induced into granulosa.
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https://www.biorxiv.org/content/10.1101/2021.10.30.466630v1.full.pdf
Mitochondria transfer can rescue oocyte aging-related infertility. However, heterologous ... When the female aged, its UC-MSCs were induced into granulosa.
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46
Maternal spindle transfer for mitochondrial disease
https://www.tandfonline.com/doi/pdf/10.1080/14647273.2021.1925168
other types of infertility is whether mitochondrial ... negative outcome is related to female meiosis being a.
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https://www.tandfonline.com/doi/pdf/10.1080/14647273.2021.1925168
other types of infertility is whether mitochondrial ... negative outcome is related to female meiosis being a.
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47
The Regulation of Mitochondrial Replacement Techniques ...
https://www.annualreviews.org/doi/pdf/10.1146/annurev-genom-111119-101815
treat infertility is not allowed in the UK. ... Clinical investigation was limited to women with serious mtDNA diseases where the con-.
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https://www.annualreviews.org/doi/pdf/10.1146/annurev-genom-111119-101815
treat infertility is not allowed in the UK. ... Clinical investigation was limited to women with serious mtDNA diseases where the con-.
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48
“Three-parent IVF” could lead to human genome editing.
https://slate.com/technology/2020/12/mitochondrial-donation-three-parent-ivf.html
Affected women now have the opportunity to give birth, for the first time, to their own biological, mitochondrial disease–free, children. But ...
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https://slate.com/technology/2020/12/mitochondrial-donation-three-parent-ivf.html
Affected women now have the opportunity to give birth, for the first time, to their own biological, mitochondrial disease–free, children. But ...
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49
Mitochondrial content reflects oocyte variability and ...
https://estudogeral.uc.pt/bitstream/10316/4749/1/file1f2e7cb6af8b44f39729acf59bd71f01.pdf
female factor infertility unfertilized oocytes and between the unexplained ... Key Words: Mitochondria, mitochondrial DNA, oocyte, embryo, ...
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https://estudogeral.uc.pt/bitstream/10316/4749/1/file1f2e7cb6af8b44f39729acf59bd71f01.pdf
female factor infertility unfertilized oocytes and between the unexplained ... Key Words: Mitochondria, mitochondrial DNA, oocyte, embryo, ...
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50
Mitochondria: the panacea to improve oocyte quality?
https://atm.amegroups.com/article/download/33240/pdf
we summarize the potential mechanism of mitochondria in oocyte and embryo development and ... of mitochondrial activity in female fertility and assisted.
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https://atm.amegroups.com/article/download/33240/pdf
we summarize the potential mechanism of mitochondria in oocyte and embryo development and ... of mitochondrial activity in female fertility and assisted.
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51
A mitochondrial DNA hypomorph of cytochrome oxidase ...
https://elifesciences.org/articles/16923
A 'male-harming' mtDNA mutation has been identified in Drosophila and impairs male fertility without impairing other male or female ...
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https://elifesciences.org/articles/16923
A 'male-harming' mtDNA mutation has been identified in Drosophila and impairs male fertility without impairing other male or female ...
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52
Transfer of autologous mitochondria from adipose tissue ...
http://www.aging-us.com/article/101332/text
Elder women suffer from low or loss of fertility because of decreasing oocyte quality as maternal aging. As energy resource, mitochondria play pivotal roles ...
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http://www.aging-us.com/article/101332/text
Elder women suffer from low or loss of fertility because of decreasing oocyte quality as maternal aging. As energy resource, mitochondria play pivotal roles ...
→ Check Latest Keyword Rankings ←
53
3 biological parents, 1 child, and an international controversy
https://www.vox.com/2018/7/24/17596354/mitochondrial-replacement-therapy-three-parent-baby-controversy
The story of mitochondrial replacement therapy shows how ethically ... prevent disease or overcome infertility, they usually get applauded.
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https://www.vox.com/2018/7/24/17596354/mitochondrial-replacement-therapy-three-parent-baby-controversy
The story of mitochondrial replacement therapy shows how ethically ... prevent disease or overcome infertility, they usually get applauded.
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54
Effects of The Mitochondrial Genome on Germ Cell Fertility
https://www.ijfs.ir/article_247959.html
The mitochondrial genome affects infertility in both male and female gametes; in sperm, it mainly releases free radicals. In the oocyte, a mutation in this ...
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https://www.ijfs.ir/article_247959.html
The mitochondrial genome affects infertility in both male and female gametes; in sperm, it mainly releases free radicals. In the oocyte, a mutation in this ...
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55
Effects of The Mitochondrial Genome on Germ Cell Fertility - SID
https://www.sid.ir/FileServer/JE/107320220202
The mitochondrial genome affects infertility in both male and female gametes; in sperm, it mainly releases free radicals. In the oocyte, a mutation in this.
→ Check Latest Keyword Rankings ←
https://www.sid.ir/FileServer/JE/107320220202
The mitochondrial genome affects infertility in both male and female gametes; in sperm, it mainly releases free radicals. In the oocyte, a mutation in this.
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56
Reproductive Medicine Involving Mitochondrial DNA ...
https://www.emjreviews.com/reproductive-health/article/reproductive-medicine-involving-mitochondrial-dna-modification-evolution-legality-and-ethics/
Mitochondrial functions are exerted through evolutionarily-developed interactions between the nucleus and mitochondria. Since 1996, fertility ...
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https://www.emjreviews.com/reproductive-health/article/reproductive-medicine-involving-mitochondrial-dna-modification-evolution-legality-and-ethics/
Mitochondrial functions are exerted through evolutionarily-developed interactions between the nucleus and mitochondria. Since 1996, fertility ...
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57
Mitochondrial donation - Fertilitypedia
https://fertilitypedia.org/edu/therapies/mitochondrial-donation
IVF method during which woman's faulty mitochondria are replaced by donated mitochondria to prevent mitochondrial diseases. Show full description. Therapies.
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https://fertilitypedia.org/edu/therapies/mitochondrial-donation
IVF method during which woman's faulty mitochondria are replaced by donated mitochondria to prevent mitochondrial diseases. Show full description. Therapies.
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58
Age-Related Female Fertility Decline Linked to Mitochondrial ...
https://www.lifespan.io/news/age-related-female-fertility-decline-linked-to-mitochondrial-mutation/
Mutations accumulate in the mitochondrial DNA of egg cells, leading to changes in cellular metabolism, which result in reduced fertility.
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https://www.lifespan.io/news/age-related-female-fertility-decline-linked-to-mitochondrial-mutation/
Mutations accumulate in the mitochondrial DNA of egg cells, leading to changes in cellular metabolism, which result in reduced fertility.
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59
Scientists discovered the mechanism of female infertility ...
http://english.gibh.cas.cn/research2020/keyachievements/202008/t20200818_241801.html
The work found that the oocytes of elder female patients carried more mitochondrial DNA mutations and had lower blastocyst formation rate than ...
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http://english.gibh.cas.cn/research2020/keyachievements/202008/t20200818_241801.html
The work found that the oocytes of elder female patients carried more mitochondrial DNA mutations and had lower blastocyst formation rate than ...
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60
Research breakthrough on male infertility: Small set of genes ...
https://www.sciencedaily.com/releases/2011/05/110513112258.htm
This is because all of the screening of mitochondrial mutations is done in females as a result of their maternal inheritance," Dr Dowling ...
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https://www.sciencedaily.com/releases/2011/05/110513112258.htm
This is because all of the screening of mitochondrial mutations is done in females as a result of their maternal inheritance," Dr Dowling ...
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61
Autologous mitochondrial microinjection
https://d-nb.info/1206991992/34
mutation and deletion have been reported in oocyte mitochondrial DNA (mtDNA) following ... while overcoming age‑related infertility in female germ cells.
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https://d-nb.info/1206991992/34
mutation and deletion have been reported in oocyte mitochondrial DNA (mtDNA) following ... while overcoming age‑related infertility in female germ cells.
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62
Human Eggs Skip Key Metabolic Reaction
https://www.genengnews.com/topics/translational-medicine/human-eggs-skip-key-metabolic-reaction/
The mitochondria of immature human eggs function differently than those of other cells, according to a new study. Specifically, one of the ...
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https://www.genengnews.com/topics/translational-medicine/human-eggs-skip-key-metabolic-reaction/
The mitochondria of immature human eggs function differently than those of other cells, according to a new study. Specifically, one of the ...
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63
Nuclear regulation of mitochondrial functions during oocyte ...
https://www.techscience.com/biocell/v44n4/41005/pdf
Key words: Mitochondria, Oocyte, Nuclear gene, Pathway, Female fertility. Abstract: Mitochondria are important in eukaryotic cells due to their functions in ...
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https://www.techscience.com/biocell/v44n4/41005/pdf
Key words: Mitochondria, Oocyte, Nuclear gene, Pathway, Female fertility. Abstract: Mitochondria are important in eukaryotic cells due to their functions in ...
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64
3-Person IVF: A Resource Page
https://www.geneticsandsociety.org/internal-content/3-person-ivf-resource-page
The only time PGD may not be an option is if close to 100 percent of a woman's mitochondrial DNA is mutated (homoplasmy.) However in such rare cases, that woman ...
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https://www.geneticsandsociety.org/internal-content/3-person-ivf-resource-page
The only time PGD may not be an option is if close to 100 percent of a woman's mitochondrial DNA is mutated (homoplasmy.) However in such rare cases, that woman ...
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65
The role of mitochondria in premature ovarian failure: A review
https://www.jocms.org/index.php/jcms/article/view/712
It has been reported that almost 20% of women who consult for infertility have signs of premature ovarian ageing. The mitochondrial disorder ...
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https://www.jocms.org/index.php/jcms/article/view/712
It has been reported that almost 20% of women who consult for infertility have signs of premature ovarian ageing. The mitochondrial disorder ...
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66
Exclusive: World's first baby born with new “3 parent” technique
https://www.newscientist.com/article/2107219-exclusive-worlds-first-baby-born-with-new-3-parent-technique/
Genes for the disease reside in DNA in the mitochondria, which provide energy for our cells and carry just 37 genes that are passed down to ...
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https://www.newscientist.com/article/2107219-exclusive-worlds-first-baby-born-with-new-3-parent-technique/
Genes for the disease reside in DNA in the mitochondria, which provide energy for our cells and carry just 37 genes that are passed down to ...
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67
'Three-person' baby boy born in Greece - BBC News
https://www.bbc.com/news/health-47889387
The baby was conceived using an experimental form of IVF that has been ... makeup from the donor woman as mitochondria have their own DNA.
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https://www.bbc.com/news/health-47889387
The baby was conceived using an experimental form of IVF that has been ... makeup from the donor woman as mitochondria have their own DNA.
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68
Modulator IVM and Mitochondrial DNA Testing
https://www.samitivejhospitals.com/article/detail/modulator-ivm-and-mitochondrial-dna-testing-modern-strides-in-fertility-treatments
Modulator IVM and Mitochondrial DNA Testing: Modern Strides in Fertility ... whether or not a woman's endometrium is ready for embryo implantation.
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https://www.samitivejhospitals.com/article/detail/modulator-ivm-and-mitochondrial-dna-testing-modern-strides-in-fertility-treatments
Modulator IVM and Mitochondrial DNA Testing: Modern Strides in Fertility ... whether or not a woman's endometrium is ready for embryo implantation.
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69
Mitochondrial Reproductive Options • Wellcome Trust Centre ...
https://www.newcastle-mitochondria.com/patient-and-public-home-page/mitochondrial-reproductive-options/
Mitochondrial donation is a novel IVF procedure. It uses eggs from both a healthy donor and a woman with mitochondrial disease. The nuclear DNA is removed ...
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https://www.newcastle-mitochondria.com/patient-and-public-home-page/mitochondrial-reproductive-options/
Mitochondrial donation is a novel IVF procedure. It uses eggs from both a healthy donor and a woman with mitochondrial disease. The nuclear DNA is removed ...
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70
Mitochondrial donation - UK Parliament
https://www.parliament.uk/globalassets/documents/commons-committees/science-technology/Mitochondrial%20donation/MITCorrespondence.pdf
infertility and genetic disease, including people wanting an opportunity to ... mitochondrial disease for a few women will put their own ...
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https://www.parliament.uk/globalassets/documents/commons-committees/science-technology/Mitochondrial%20donation/MITCorrespondence.pdf
infertility and genetic disease, including people wanting an opportunity to ... mitochondrial disease for a few women will put their own ...
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71
Mitochondrial DNA mutations and male infertility Review Article
http://www.bioline.org.br/pdf?hg09022
Infertility can arise either because of the male factor or female factor or both. According to the current estimates, 15% of couples.
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http://www.bioline.org.br/pdf?hg09022
Infertility can arise either because of the male factor or female factor or both. According to the current estimates, 15% of couples.
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72
UK doctors select first women to have 'three-person babies'
https://www.theguardian.com/science/2018/feb/01/permission-given-to-create-britains-first-three-person-babies
Mitochondrial donation therapy was pioneered at Newcastle by the neurologist Doug Turnbull to prevent women passing on harmful mitochondrial DNA ...
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https://www.theguardian.com/science/2018/feb/01/permission-given-to-create-britains-first-three-person-babies
Mitochondrial donation therapy was pioneered at Newcastle by the neurologist Doug Turnbull to prevent women passing on harmful mitochondrial DNA ...
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73
Clinical translation of mitochondrial replacement therapy in ...
https://www.facetsjournal.com/doi/10.1139/facets-2020-0062
Rather, it is a form of IVF that involves the manipulation of egg cells to give women affected by mitochondrial diseases the opportunity to ...
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https://www.facetsjournal.com/doi/10.1139/facets-2020-0062
Rather, it is a form of IVF that involves the manipulation of egg cells to give women affected by mitochondrial diseases the opportunity to ...
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74
Ovarian ageing may be associated with mitochondrial ...
https://ivi-fertility.com/blog/ovarian-ageing-mitochondrial-dysfunction/
Ovarian ageing is becoming an increasingly common cause of infertility. What role have mitochondria in the loss of fertility related to age?
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https://ivi-fertility.com/blog/ovarian-ageing-mitochondrial-dysfunction/
Ovarian ageing is becoming an increasingly common cause of infertility. What role have mitochondria in the loss of fertility related to age?
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75
Germline Energetics, Aging, and Female Infertility - AAPEC
http://www.aapec.org/images/BibliotecaVirtual/1.3.1.cell_metab_2013_17_6_838-850.pdf
discussions of how female fertility and ovarian life span might be modulated in mammals. ... resveratrol, which boosts mitochondrial function and extends.
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http://www.aapec.org/images/BibliotecaVirtual/1.3.1.cell_metab_2013_17_6_838-850.pdf
discussions of how female fertility and ovarian life span might be modulated in mammals. ... resveratrol, which boosts mitochondrial function and extends.
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76
Lesbian motherhood and mitochondrial replacement techniques
https://jme.bmj.com/content/44/12/835
Prior to the advent of MRTs, women at risk of transmitting an mtDNA ... and possibly by other non-mtDNA infertile couples, should be factored in when ...
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https://jme.bmj.com/content/44/12/835
Prior to the advent of MRTs, women at risk of transmitting an mtDNA ... and possibly by other non-mtDNA infertile couples, should be factored in when ...
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77
Mitochondrial donation treatment - HFEA
https://www.hfea.gov.uk/treatments/embryo-testing-and-treatments-for-disease/mitochondrial-donation-treatment/
A woman who donates their eggs and/or embryos for use in other women's mitochondrial donation treatment will not be the genetic parent of the resulting ...
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https://www.hfea.gov.uk/treatments/embryo-testing-and-treatments-for-disease/mitochondrial-donation-treatment/
A woman who donates their eggs and/or embryos for use in other women's mitochondrial donation treatment will not be the genetic parent of the resulting ...
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78
Genetics of mitochondrial dysfunction and infertility
https://librarysearch.bcu.ac.uk/discovery/fulldisplay?docid=cdi_proquest_miscellaneous_1868317289&context=PC&vid=44BCU_INST:44BCU_INST&lang=en&search_scope=MyInst_and_CI&adaptor=Primo%20Central&tab=Everything&query=null%2C%2CMitochondrial%20encephalomyopathies%3A%20an%20update%2CAND&mode=advanced
Increasingly, mitochondria are being recognized as having an important role in fertility. Indeed in assisted reproductive technologies mitochondrial ...
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https://librarysearch.bcu.ac.uk/discovery/fulldisplay?docid=cdi_proquest_miscellaneous_1868317289&context=PC&vid=44BCU_INST:44BCU_INST&lang=en&search_scope=MyInst_and_CI&adaptor=Primo%20Central&tab=Everything&query=null%2C%2CMitochondrial%20encephalomyopathies%3A%20an%20update%2CAND&mode=advanced
Increasingly, mitochondria are being recognized as having an important role in fertility. Indeed in assisted reproductive technologies mitochondrial ...
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79
Controversial 'three-person' IVF used for baby boy born ... - CNN
https://www.cnn.com/2019/04/11/health/birth-experimental-ivf-greece-scln-intl
This new advancement in in vitro fertilization, which was developed by doctors in the UK, allows the donation of mitochondria, which provides ...
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https://www.cnn.com/2019/04/11/health/birth-experimental-ivf-greece-scln-intl
This new advancement in in vitro fertilization, which was developed by doctors in the UK, allows the donation of mitochondria, which provides ...
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80
Female reproductive life span is extended by targeted removal ...
https://www.science.org/doi/10.1126/sciadv.abn4564
We find that obesity causes ovarian fibrosis similar to that of reproductive aging, and reveal that mitochondrial damage in stromal cells is the ...
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https://www.science.org/doi/10.1126/sciadv.abn4564
We find that obesity causes ovarian fibrosis similar to that of reproductive aging, and reveal that mitochondrial damage in stromal cells is the ...
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81
Infertile couple have baby using mitochondrial donation
https://www.fertilitycrete.gr/news-publications/infertile-couple-have-baby-using-mitochondrial-donation/
› news-publications › infert...
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https://www.fertilitycrete.gr/news-publications/infertile-couple-have-baby-using-mitochondrial-donation/
› news-publications › infert...
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82
Mitochondrial dysfunction in oocytes of obese mothers ...
https://journals.biologists.com/dev/article/142/4/681/47138/Mitochondrial-dysfunction-in-oocytes-of-obese
Impaired fertility also commonly occurs with obesity; for instance, overweight women often require assisted reproductive technologies, ...
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https://journals.biologists.com/dev/article/142/4/681/47138/Mitochondrial-dysfunction-in-oocytes-of-obese
Impaired fertility also commonly occurs with obesity; for instance, overweight women often require assisted reproductive technologies, ...
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83
What is the IVF technique called mitochondrial donation, and ...
https://www.abc.net.au/news/science/2022-03-28/three-parent-babies-mitochondrial-donation-ivf-genetic-disease/100934276
Mitochondrial donation is an IVF technique that replaces a woman's defective mitochondria with those from another woman's egg to help her ...
→ Check Latest Keyword Rankings ←
https://www.abc.net.au/news/science/2022-03-28/three-parent-babies-mitochondrial-donation-ivf-genetic-disease/100934276
Mitochondrial donation is an IVF technique that replaces a woman's defective mitochondria with those from another woman's egg to help her ...
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84
A groundbreaking way to stop mitochondrial disease - TEDMED
https://www.tedmed.com/talks/show?id=689133
Fertility expert Mary Herbert and her team are preventing the transmission of mitochondrial DNA disease using nuclear transplantation.
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https://www.tedmed.com/talks/show?id=689133
Fertility expert Mary Herbert and her team are preventing the transmission of mitochondrial DNA disease using nuclear transplantation.
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85
Mitochondrial DNA in Fresh versus Frozen Embryo Culture ...
https://www.dovepress.com/mitochondrial-dna-in-fresh-versus-frozen-embryo-culture-media-of-polyc-peer-reviewed-fulltext-article-PGPM
To summarize, the mtDNA/gDNA ratio in embryo culture media of PCOS women undergoing IVF is significantly higher with pregnancy. Thus, it ...
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https://www.dovepress.com/mitochondrial-dna-in-fresh-versus-frozen-embryo-culture-media-of-polyc-peer-reviewed-fulltext-article-PGPM
To summarize, the mtDNA/gDNA ratio in embryo culture media of PCOS women undergoing IVF is significantly higher with pregnancy. Thus, it ...
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86
The role of mitochondria in women infertility - سیویلیکا
https://civilica.com/doc/736649/certificate/print/
Mitochondria affect all aspects of mammalian reproduction. They are key factors for optimal oocyte maturation, egg fertilization and embryonic development.
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https://civilica.com/doc/736649/certificate/print/
Mitochondria affect all aspects of mammalian reproduction. They are key factors for optimal oocyte maturation, egg fertilization and embryonic development.
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87
Mitochondrial DNA
https://www.genome.gov/genetics-glossary/Mitochondrial-DNA
Mitochondrial DNA is the circular chromosome found inside the cellular organelles called mitochondria. Located in the cytoplasm, ...
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https://www.genome.gov/genetics-glossary/Mitochondrial-DNA
Mitochondrial DNA is the circular chromosome found inside the cellular organelles called mitochondria. Located in the cytoplasm, ...
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88
Mitochondria in reproduction and fertility - HSTalks
https://hstalks.com/t/3817/mitochondria-in-reproduction-and-fertility-mitocho/
› mitochondria-in-reproduction-and...
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https://hstalks.com/t/3817/mitochondria-in-reproduction-and-fertility-mitocho/
› mitochondria-in-reproduction-and...
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89
mitochondrial disease | ICaMB – Inside Cells and Molecules ...
https://blogs.ncl.ac.uk/icamblog/tag/mitochondrial-disease/
Almost 2,500 women in the UK have mutations in some or all of their mtDNA that can cause disease. Defects of this mitochondrial genome, ...
→ Check Latest Keyword Rankings ←
https://blogs.ncl.ac.uk/icamblog/tag/mitochondrial-disease/
Almost 2,500 women in the UK have mutations in some or all of their mtDNA that can cause disease. Defects of this mitochondrial genome, ...
→ Check Latest Keyword Rankings ←
90
Mitochondria: Participation to infertility as source of energy ...
https://agris.fao.org/agris-search/search.do?recordID=US201800352818
This is reflected in the low numbers of mtDNA observed in degenerate oocytes obtained through super ovulation protocols during assisted reproductive technology ...
→ Check Latest Keyword Rankings ←
https://agris.fao.org/agris-search/search.do?recordID=US201800352818
This is reflected in the low numbers of mtDNA observed in degenerate oocytes obtained through super ovulation protocols during assisted reproductive technology ...
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91
Pre fertilization DNA transfer to avoid mitochondrial disease ...
https://medicaldialogues.in/mdtv/obstetrics-gynaecology/videos/pre-fertilization-dna-transfer-to-avoid-mitochondrial-disease-inheritance-appears-safe-97630
Transferring the nuclear genome from one egg into the cytoplasm of a donor egg is a strategy to enable women carrying mutations in their ...
→ Check Latest Keyword Rankings ←
https://medicaldialogues.in/mdtv/obstetrics-gynaecology/videos/pre-fertilization-dna-transfer-to-avoid-mitochondrial-disease-inheritance-appears-safe-97630
Transferring the nuclear genome from one egg into the cytoplasm of a donor egg is a strategy to enable women carrying mutations in their ...
→ Check Latest Keyword Rankings ←
92
Female Infertility: Core Principles and Clinical Management
https://books.google.com/books?id=292RDwAAQBAJ&pg=PA139&lpg=PA139&dq=mitochondria+female+infertility&source=bl&ots=JGZKgWJjB_&sig=ACfU3U3ildeJPeBeQBIe5JKuGfQHwN4DQA&hl=en&sa=X&ved=2ahUKEwjor4CEhtv7AhUnsaQKHQRUCyoQ6AF6BQjVAhAD
139 Mitochondrial donation MIIoocytes Enucleation Cytoplast Transfer Fertilization of reconstituted MII oocyte Karyoplast Mitochondria with pathogenic mtDNA ...
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https://books.google.com/books?id=292RDwAAQBAJ&pg=PA139&lpg=PA139&dq=mitochondria+female+infertility&source=bl&ots=JGZKgWJjB_&sig=ACfU3U3ildeJPeBeQBIe5JKuGfQHwN4DQA&hl=en&sa=X&ved=2ahUKEwjor4CEhtv7AhUnsaQKHQRUCyoQ6AF6BQjVAhAD
139 Mitochondrial donation MIIoocytes Enucleation Cytoplast Transfer Fertilization of reconstituted MII oocyte Karyoplast Mitochondria with pathogenic mtDNA ...
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93
9 Benefits of Coenzyme Q10 (CoQ10) - Healthline
https://www.healthline.com/nutrition/coenzyme-q10
The mitochondria are in charge of producing energy. ... Female fertility decreases with age due to a decline in the number and quality of ...
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https://www.healthline.com/nutrition/coenzyme-q10
The mitochondria are in charge of producing energy. ... Female fertility decreases with age due to a decline in the number and quality of ...
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94
Mitochondrial donation
https://www.health.gov.au/our-work/mitochondrial-donation
Mitochondrial donation is an IVF-based assisted reproductive technology. It has the potential to prevent mitochondrial disease in babies ...
→ Check Latest Keyword Rankings ←
https://www.health.gov.au/our-work/mitochondrial-donation
Mitochondrial donation is an IVF-based assisted reproductive technology. It has the potential to prevent mitochondrial disease in babies ...
→ Check Latest Keyword Rankings ←
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