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1 Weight neutrality with the DPP-4 inhibitor, vildagliptin - PubMed
https://pubmed.ncbi.nlm.nih.gov/20730070/
Dipeptidyl peptidase (DPP)-4 inhibitors are generally weight-neutral, although modest weight loss has been observed with the DPP-4 inhibitor ...
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2 Weight Maintenance With Dipeptidyl Peptidase 4 (DPP4 ...
https://clinicaltrials.gov/ct2/show/NCT02941445
In addition, weight loss achieved with liraglutide is often non-sustainable after treatment cessation. Although DPP-4 inhibitors are weight ...
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3 The weight reduction could be achieved on DPP-IV inhibitors ...
https://www.endocrine-abstracts.org/ea/0029/ea0029p744
Usually dipeptidyl peptidase-IV (DPP-IV) inhibitors considered as weight neutral and glucagon-like peptide-1 receptor agonists are associated with weight loss.
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4 Acarbose With Comparable Glucose-Lowering but Superior ...
https://www.frontiersin.org/articles/10.3389/fendo.2020.00288/full
Conclusions: Acarbose and DPP-4is have similar glucose-lowering effects, but the weight-loss effects of acarbose are superior. Therefore, in the ...
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5 DPP-4 Inhibitors and Fat Metabolism in Patients with Type 2 ...
https://www.intechopen.com/books/diabetes-and-its-complications/dpp-4-inhibitors-and-fat-metabolism-in-patients-with-type-2-diabetes
Possible mechanisms partaking in the positive effect on lipid profile from therapy by DPP-4 inhibitor in combination with metformin could be ...
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6 DPP-4 Inhibitors - diaTribe
https://diatribe.org/dpp-4-inhibitors
DPP-4s have a low risk of hypoglycemia (low blood sugar) unless used together with sulfonylureas or insulin. · DPP-4 is an oral drug (a pill) so ...
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7 Decrease of dipeptidyl peptidase 4 activity is associated with ...
https://link.springer.com/article/10.1007/s11695-020-05200-0
To summarize, we described a significant reduction in DPP4 activity following surgically induced weight loss which was associated both with an ...
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8 Impact of Dipeptidyl Peptidase-4 Inhibitors on Glycemic ...
https://www.karger.com/Article/FullText/506863
Studies on the influence of DPP-4 inhibitors on patient weight demonstrated variable results but are generally considered to be neutral. Studies regarding ...
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9 DPP-4 Inhibitors (Gliptins) - Suitability, Benefits & Side Effects
https://www.diabetes.co.uk/diabetes-medication/dpp-4-inhibitors.html
DPP-4 inhibitors may help with weight loss as well as decreasing blood glucose levels, but have been linked with higher rates of pancreatitis. Drugs in this ...
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10 Dipeptidyl peptidase 4 (DPP-4) inhibitors for the treatment of ...
https://www.uptodate.com/contents/dipeptidyl-peptidase-4-dpp-4-inhibitors-for-the-treatment-of-type-2-diabetes-mellitus
Initial therapy in most patients with type 2 diabetes should begin with diet, weight reduction, exercise, and metformin (in the absence of ...
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11 Choosing between GLP-1 Receptor Agonists and DPP-4 ...
https://www.hindawi.com/journals/jnme/2012/381713/
GLP-1 receptor agonists appear to lower blood glucose to a greater extent and promote more weight loss than DPP-4 inhibitors, which are weight neutral. They ...
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12 DPP-4 inhibitors and GLP-1RAs: cardiovascular safety and ...
https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-022-00410-2
While DPP-4 expression is significantly increased in patients with obesity and T2DM, the incretin effect is markedly impaired. Early studies ...
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13 Choosing GLP-1 Receptor Agonists or DPP-4 Inhibitors
https://diabetesjournals.org/clinical/article/30/1/3/35430/Choosing-GLP-1-Receptor-Agonists-or-DPP-4
More specifically, depending on background glucose-lowering therapy, a weight loss of 1–4 kg is generally observed in patients treated with a ...
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14 Body weight-loss effect of DPP4 inhibitors in established ...
https://www.researchgate.net/figure/Body-weight-loss-effect-of-DPP4-inhibitors-in-established-obese-mice-after-4-week_fig5_285595246
› figure › Body-weight-loss-...
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15 10 Diabetes Medications That Cause Weight Gain (or Loss)
https://www.goodrx.com/conditions/diabetes/diabetes-medications-that-can-cause-weight-gain
Dipeptidyl peptidase-4 (DPP-4) inhibitors (or “gliptins”) are a commonly-used group of diabetes medications. They lower blood sugar by helping ...
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16 Dipeptidyl Peptidase IV Inhibitor - ScienceDirect.com
https://www.sciencedirect.com/topics/nursing-and-health-professions/dipeptidyl-peptidase-iv-inhibitor
This class of drugs has a modest effect in reducing HbA1c and no effect on body weight. Early concerns about an increased risk of acute pancreatitis and ...
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17 dpp-4_inhibitors [TUSOM | Pharmwiki] - TMedWeb
https://tmedweb.tulane.edu/pharmwiki/doku.php/dpp-4_inhibitors
The effect produced by DPP-4 inhibitors is dependent on endogenous GLP-1 levels, and produce a modest effect on GLP-1 activity compared to ...
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18 The dipeptidyl peptidase‐4 (DPP‐4) inhibitor teneligliptin ...
https://febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.12498
To clarify the effects of a dipeptidyl peptidase-4 (DPP-4) inhibitor on whole-body energy metabolism, we treated mice fed a high-fat diet ...
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19 Sodium Glucose Cotransporter 2 and Dipeptidyl Peptidase-4 ...
https://www.endocrinepractice.org/article/S1530-891X(20)35785-2/abstract
Recent clinical evidence shows that SGLT2 inhibitor/DPP-4 inhibitor therapy is an effective combination for T2DM treatment, providing glycated hemoglobin (HbA1c) ...
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20 Algorithm Predicts Response to SGLT2, DPP-4 Inhibitors in ...
https://www.medscape.com/viewarticle/963751
They also created additional regression models for the outcomes of discontinuation of the index treatment and weight loss. The study population ...
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21 DPP-IV Inhibitors - The Johns Hopkins Patient Guide to Diabetes
https://hopkinsdiabetesinfo.org/medications-for-type-2-diabetes-dpp-iv-inhibitors/
Patients generally don't gain or lose weight on these medications. When taken alone, DPP-IV inhibitors do not usually cause low blood glucose.
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22 Does Janumet cause weight gain? - Drugs.com
https://www.drugs.com/medical-answers/janumet-weight-gain-3570577/
Metformin · Alpha-glucosidase inhibitors such as acarbose (Precose) and miglitol (Glyset) · Dipeptidyl peptidase-4 (DPP-4) inhibitors, such as ...
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23 GLP-1's and DPP-4 inhibitors
http://www.thediabetesdoc.com/incretins
Semaglutide has been associated with greater weight loss. The weight-loss benefits associated with this class of drugs are typically described as an early sense ...
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24 Characterization of combined linagliptin and Y2R ... - Gubra
https://www.gubra.dk/wp-content/uploads/2021/04/Hansen_2021_Sci-Rep_DIO-mice-linaglipitin-Y2R-agonist-combo.pdf
In contrast to GLP‑1 analogues, DPP‑IV inhibitors are weight‑neutral. ... GLP-1 receptor agonists, DPP-IV inhibitors do not promote weight loss18.
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25 Weight Management for Patients with Type 2 Diabetes
https://www.pceconsortium.org/documents/DIabWeightManagement.pdf
loss (~5% of body weight) in overweight or obese patients with T2D has been shown to improve ... (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT-.
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26 Journal of Applied Medical Sciences
http://www.scienpress.com/journal_focus.asp?Main_Id=71&Sub_id=IV&Issue=1316
Influence of DPP-4 Inhibitors on Weight in Newly Diagnosed Type-2 Diabetic Patients in Egypt ... Background: The prevalence of type-2 diabetes mellitus (T2DM) is ...
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27 Characterization of combined linagliptin and Y2R ... - Nature
https://www.nature.com/articles/s41598-021-87539-7
We report that linagliptin does not enhance anorectic and weight loss responses to Y2R agonist treatment in DIO mice. DPP-IV inhibitors may ...
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28 What Are My Options? | ADA - American Diabetes Association
https://diabetes.org/healthy-living/medication-treatments/oral-medication/what-are-my-options
DPP-4 inhibitors do not tend to cause weight gain and tend to have a neutral or positive effect on cholesterol levels. Alogliptin (Nesina), linagliptin ...
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29 DPP-4 inhibitors (gliptins) - Diabetes UK
https://www.diabetes.org.uk/guide-to-diabetes/managing-your-diabetes/treating-your-diabetes/tablets-and-medication/dpp-4-inhibitors-gliptins
DPP-4 inhibitors work by blocking the action of DPP-4, an enzyme which destroys the hormone incretin. Incretins help the body produce more insulin only when ...
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30 Effects of Sitagliptin as Monotherapy and Add-On to Metformin ...
https://www.thieme-connect.com/products/ejournals/pdf/10.1055/a-1555-2797.pdf
Weight Loss among Overweight and Obese Patients with Type 2 ... ence of DPP-4 inhibitors on reducing weight and BMI, there are.
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31 Weight Beneficial Treatments for Type 2 Diabetes
https://academic.oup.com/jcem/article/96/11/3337/2834262
Dipeptidyl peptidase-4 (DPP-4) inhibitors and bile acid sequestrants are weight-neutral. Liraglutide and exenatide appear to have similar effects on weight; ...
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32 The new class war: SGLT2 inhibitors versus DPP-4 inhibitors
https://adomeint.org/docs/blog/DPCA-2-3_119-23_wm.pdf
Glucose loss and thus calorie loss in the urine, as a result of an SGLT2 inhibitor, can result in rapid, significant and sustained weight loss (approximately 2– ...
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33 Dipeptidyl peptidase-4 inhibitors for treatment of type 2 ...
https://www.bmj.com/content/344/bmj.e1369
DPP-4 inhibitors had a favourable weight profile compared with sulfonylureas (weighted mean difference −1.92, −2.34 to −1.49) or pioglitazone ...
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34 Efficacy and hypoglycemic risk of sitagliptin in obese/overw...
https://journals.lww.com/md-journal/fulltext/2019/09060/efficacy_and_hypoglycemic_risk_of_sitagliptin_in.54.aspx
3.3.4 Weight loss ... Six studies reported weight loss. There were 1115 participants in the sitagliptin group and 1226 participants in the GLP-1 receptor agonist ...
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35 Dipeptidyl Peptidase-4 Inhibitor Sitagliptin Prevented Weight ...
https://www.liebertpub.com/doi/pdf/10.1089/met.2017.0095
Background: Weight loss is often nonsustainable after liraglutide cessation. The present study is the first insight into the potential prevention of weight ...
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36 Diabetes Drugs Used in Combination (GLP-1 Agonists + DPP ...
https://ahpnetwork.com/wp-content/uploads/2019/03/March-2019-GLP1s-and-DPP4is_Pharmacy-Pearl.pdf
loss (DPP-4 inhibitors are weight-neutral), and have been proven to decrease risk of negative cardiovascular outcomes (liraglutide and semaglutide), therefore.
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37 Use of DPP-4 inhibitors in type 2 diabetes: focus on sitagliptin
https://www.tandfonline.com/doi/full/10.2147/dmsott.s7327
Furthermore, sitagliptin is body weight neutral or induces a slight body weight reduction. Sitagliptin may be used in the early stages of ...
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38 Weight loss differences seen between glucagon-like peptide ...
https://www.japha.org/article/S1544-3191(21)00283-1/abstract
SGLT-2 inhibitors, when used in combination with background diabetes regimens, can lead to more statistically significant weight loss than GLP-1 ...
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39 SGLT-2 Inhibitors Vs DPP-4 Inhibitors Vs. GLP1's For Type 2 ...
https://www.diabetesincontrol.com/sglt-2-inhibitors-vs-dpp-4-inhibitors-vs-glp1s-for-type-2-diabetes/
The combination therapy provided a 3.41 kg (7.52 lbs) weight loss over baseline, compared with 1.54 kg (3.40 lbs) on exenatide alone and 2.19 kg ...
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40 DPP4s - MedStar Health InFocus
https://medstarhealthinfocus.org/endocrinology/dpp4s/
When taken alone or in combination with metformin, DPP-4 pills do not cause weight loss or weight gain and have a low risk of low blood sugar or ...
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41 Beneficial Effects of Evogliptin, a Novel Dipeptidyl Peptidase 4 ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144064
After the 4 week treatment, weight loss and blood glucose reductions were consistently observed with multiple DPP4 inhibitors. Moreover, after 2 ...
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42 What are DPP-4 Inhibitors (gliptins)? - Your Diabetes Your Way
https://lsc.mydiabetes.com/resources/internal/what-are-dpp-4-inhibitors-gliptins/
DPP4- inhibitors are usually prescribed when diet and exercise alone have not been enough to control your blood glucose levels.
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43 Dipeptidyl Peptidase 4 (DPP4) as A Novel Adipokine - MDPI
https://www.mdpi.com/2227-9059/10/9/2306/pdf
In mice with diet-induced obesity, Ramalho and collaborators showed that treatment with an antagonist of substance P-receptor (NK1-R) resulted ...
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44 Second steps in managing type 2 diabetes - NPS MedicineWise
https://www.nps.org.au/assets/61d11a91bea9812b-76489905063c-p141-Petersons.pdf
Hypoglycaemia, weight gain. Kidney impairment (dose reduction may be required), severe liver disease, elderly. Dipeptidyl peptidase-4 inhibitors.
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45 DPP-4 inhibitors in the management of type 2 diabetes - ORBi
https://orbi.uliege.be/bitstream/2268/117703/1/DPP4%20inhibitors%20in%20the%20management%20of%20type%202%20diabetesOCR.pdf
Numerous placebo-controlled trials have demonstrated both the efficacy and safety of DPP-4 inhibitors in patients with T2DM treated with diet and exercise (drug ...
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46 Results from the CANTABILE study
https://www.diabetesresearchclinicalpractice.com/article/S0168-8227(21)00396-X/fulltext
SGLT2 inhibitors are more effective for body weight reduction than DPP-4 inhibitors. Abstract. Aims. The aim of this study was to compare the ...
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47 GLP-1 Agonists Superior to DPP-4 Inhibitors for Reducing ...
https://www.endocrinologyadvisor.com/home/type-2-diabetes-advisor/glp-1-agonists-superior-to-dpp-4-inhibitors-for-reducing-hba1c-weight-in-t2d/
Treatment with glucagon-like peptide-1 (GLP-1) agonists is associated with greater reductions in glycated hemoglobin (HbA1c) and body weight ...
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48 What are DPP-4 Inhibitors (gliptins)? | Information Site
https://mydiabetesmyway.scot.nhs.uk/resources/internal/what-are-dpp-4-inhibitors-gliptins/
DPP4- inhibitors are usually prescribed when diet and exercise alone have not been enough to control your blood glucose levels.
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49 weight neutrality with the DPP-4 inhibitor, vildagliptin
https://pdfs.semanticscholar.org/4579/1e3579abcfac0155fc0f787ac179fb998af2.pdf
Abstract: Various factors may confound how diabetes medications affect a patient's weight. Agents that induce hypoglycemia may promote weight gain through ...
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50 Dipeptidyl-peptidase-4 Inhibitors for Treatment of Type 2 ...
https://www.aafp.org/pubs/afp/issues/2009/0301/p372.html
When used as monotherapy or in conjunction with metformin (Glucophage) or thiazolidinediones, the DPP-4 inhibitor sitagliptin (Januvia) ...
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51 Elsevier Drug Class Overview | Dipeptidyl-peptidase-4 (DPP-4 ...
https://elsevier.health/en-US/preview/dipeptidyl-peptidase-4-dpp-4-inhibitors
DPP-4 inhibitors reduce postprandial glucose with minimal risk of hypoglycemia and gastrointestinal adverse effects; they are also weight ...
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52 Weight Loss Pharmacotherapy of Obese Non-Diabetic and ...
https://www.omicsonline.org/open-access/weight-loss-pharmacotherapy-of-obese-nondiabetic-and-type-2-diabetic-patients-2165-7904-1000277.php?aid=61281
Another group of oral anti-diabetic agents DPP-4 inhibitors (sitagliptin, vildagliptin, saxagliptin and alogliptin) generally has a neutral effect on weight.
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53 Diabetes treatment: Medications for type 2 diabetes
https://www.mayoclinic.org/diseases-conditions/type-2-diabetes/in-depth/diabetes-treatment/art-20051004
Blood sugar levels drop too low; Weight gain; Skin rash; Nausea or vomiting if you drink alcohol. Dipeptidyl-peptidase 4 (DPP-4) inhibitors. Medications.
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54 DPP-4 Inhibitors: What Is Their Place in Therapy?
https://www.uspharmacist.com/article/dpp-4-inhibitors-what-is-their-place-in-therapy
Though DPP-4 inhibitors do not promote weight loss, they are weight neutral and can prevent further weight gain. Other therapies that target ...
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55 What are DPP-4 Inhibitors (gliptins)? | Wigan | Tameside NHS
https://diabetesmyway.nhs.uk/resources/internal/what-are-dpp-4-inhibitors-gliptins/
DPP4- inhibitors are usually prescribed when diet and exercise alone have not been enough to control your blood glucose levels.
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56 Effects of SGLT2 inhibitors on weight loss in patients with type ...
https://www.europeanreview.org/wp/wp-content/uploads/199-211-Effects-of-SGLT2-inhibitors-on-weight-loss-in-patients-with-type-2-diabetes-mellitus.pdf
porter type 2) inhibitors are a new class of drugs ... diabetes and the induction of weight loss in pa- tients with such condition, ... DPP-4 inhibitor.
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57 Mice lacking dipeptidyl peptidase IV are protected ... - PNAS
https://www.pnas.org/doi/10.1073/pnas.0631828100
Together, these observations suggest that chronic deletion of DP-IV gene has significant impact on body weight control and energy homeostasis, providing ...
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58 Combination therapy with once-weekly glucagon like peptide ...
https://www.pharmacypractice.org/index.php/pp/article/view/1588
Conclusions: Concomitant use of once-weekly GLP-1 RAs and DPP-4 inhibitors provides only modest improvement in glycemic control with minimal weight loss ...
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59 FDA warns that DPP-4 inhibitors for type 2 diabetes may ...
https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-warns-dpp-4-inhibitors-type-2-diabetes-may-cause-severe-joint-pain
DPP-4 inhibitors are used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. When untreated, type 2 diabetes can ...
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60 Glyxambi Approved, Combo Provides Actions of SGLT2, DPP ...
https://www.ajmc.com/view/glyxambi-approved-combo-provides-actions-of-sglt2-dpp-4-inhibitors-for-patients-with-t2dm
DPP-4 inhibitors increase hormones to encourage the pancreas to produce more insulin, and by stimulating the liver to produce less glucose.
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61 DPP-4 inhibitors versus SGLT-2 inhibitors; cons and pro
https://www.imedpub.com/articles/dpp4-inhibitors-versus-sglt2-inhibitors-cons-and-pro.php?aid=19763
These agents may be associated with significant side effects such as hypoglycemia (sulfonylureas, insulin), weight gain (sulfonylureas, ...
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62 DPP4 deletion in adipose tissue improves hepatic insulin ...
https://journals.physiology.org/doi/10.1152/ajpendo.00323.2019
Analogously, the experimental DPP4 inhibitor MK0626 improved diet-induced hepatic insulin resistance by enhancing insulin suppression of hepatic ...
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63 Newer Diabetes Medications and Combinations (GLP-1 ...
https://www.orpdl.org/durm/meetings/meetingdocs/2016_09_29/archives/2016_09_29_DiabetesDERPSummaryReport.pdf
differences in weight changes favored metformin over DPP-4 inhibitors. ... Weight loss was similar with dual therapy and SGLT2 inhibitor monotherapy based ...
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64 DPP4 in Cardiometabolic Disease | Circulation Research
https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.116.305665
DPP4 inhibitors are modestly effective in reducing HbA1c (glycated ... Although diet and lifestyle approaches are fundamental to the ...
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65 Commissioning Support DPP-4 inhibitors ('Gliptins'):
https://ccg.centreformedicinesoptimisation.co.uk/download/5abe9a2973f41a72fca42b6b9b1e55a2
NICE guidance (CG87) states that treatment with DPP-4 inhibitor therapy ... Weight-loss targets of ≥ 3% of initial body weight after 6 months are ...
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66 Effectiveness and Safety of Adding Basal Insulin Glargine in ...
https://www.e-dmj.org/journal/view.php?number=642
The combination add-on therapy of insulin glargine, on metformin and DPP-4 inhibitors with or without SU was safe and efficient in reducing ...
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67 SGLT2 Inhibitor and DPP4 Inhibitor Co-Administration In Type ...
https://www.rroij.com/open-access/sglt2-inhibitor-and-dpp4-inhibitor-coadministration-in-type-2diabetes-are-we-near-the-promised-land-.php?aid=69647
2. Weight loss attributable to the SGLT2 inhibitors is approximately in the range of 1-5 kgs [46-53] which is initially due to osmotic diuresis [54] and later ...
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68 List of DPP-4 Inhibitors: Uses, most common brands ... - NiceRx
https://www.nicerx.com/classes/dpp-4-inhibitors/
DPP-4 inhibitors are FDA-approved as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes, which is a risk factor for ...
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69 Cardiovascular Outcomes Trials New Antidiabetic Drug
https://www.cfrjournal.com/articles/cardiovascular-outcomes-trials-antidiabetic-drug
DPP-4 inhibitors showed neutral effects on cardiovascular outcomes, but may increase the incidence of heart failure.
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70 GLP-1 Agonists + DPP-4 Inhibitors
https://content.highmarkprc.com/Files/Region/navinet/EducationManuals/PopHealth/pop-health-toolkit-diabetes-mellitus.pdf
Baptist Gallwitz, Clinical Use of DPP-4 Inhibitors, Frontiers in Endocrinology, 10.3389/fendo.2019.00389, 10, ... REDUCTION, ARE ASSOCIATED WITH WEIGHT LOSS.
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71 SGLT2 inhibitor provides greater weight loss benefits than ...
https://specialty.mims.com/topic/sglt2-inhibitor-provides-greater-weight-loss-benefits-than-metformin--gliptins
SGLT2 inhibitors also increased the number of patients achieving ≥5-percent weight loss, with their effect on weight reduction correlated with ...
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72 Incretin Mimetics and DPP-IV Inhibitors
https://www.jabfm.org/content/jabfp/19/6/612.full.pdf
Dipeptidyl peptidase-IV (DPP-IV) inhibitors suppress the degradation of many ... above ideal target weight.14 In contrast, weight loss.
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73 Development of a treatment selection algorithm for SGLT2 and ...
https://www.thelancet.com/journals/landig/article/PIIS2589-7500(22)00174-1/fulltext
SGLT2 and DPP-4 inhibitors are recommended glucose-lowering treatment options for people with ... although SGLT2 inhibitors are associated with weight loss.
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74 DPP-4/SGLT2 inhibitor combined therapy for type 2 diabetes
https://wileymicrositebuilder.com/trends/wp-content/uploads/sites/23/2017/11/DPP4-SGLT2-lsw.pdf
comparable with that of the DPP-4 inhibitors, and dapagliflozin, ... cannot be maintained with diet, lifestyle change and metformin,. DPP-4/SGLT2 inhibitor ...
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75 New Diabetes Medications - OHSU
https://www.ohsu.edu/sites/default/files/2020-03/CPD%20IM20-Thu-10-Hettinger.pdf
BACKGROUND: Saxagliptin and alogliptin are part of the class of dipeptidyl peptidase-4 (DPP-4) inhibitor drugs, which are used with diet and exercise to ...
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76 Therapeutic Class Overview
https://www.medicaid.nv.gov/Downloads/provider/Dipeptidyl_2019-09.pdf
The DPP-4 inhibitors or gliptins (alogliptin, linagliptin, saxagliptin, sitagliptin) are indicated as adjuncts to diet and.
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77 Dipeptidyl peptidase-4 (DPP-4) inhibitors for type 2 diabetes ...
https://www.cochrane.org/CD006739/ENDOC_dipeptidyl-peptidase-4-dpp-4-inhibitors-for-type-2-diabetes-mellitus
Weight gain was not observed after sitagliptin and vildagliptin therapy. Overall, sitagliptin and vildagliptin were well tolerated, no severe ...
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78 Glucose-lowering medicines for type 2 diabetes - RACGP
https://www.racgp.org.au/afp/2015/may/glucose-lowering-medicines-for-type-2-diabetes
Glucagon-like peptide 1 agonists and sodium-glucose co-transporter 2 inhibitors provide some assistance in weight loss as well as improving blood glucose con- ...
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79 Anti-diabetic Treatment in Obese Patients with Type 2 ...
https://www.touchendocrinology.com/diabetes/journal-articles/anti-diabetic-treatment-in-obese-patients-with-type-2-diabetes-effects-of-medication-on-body-weight-2/
42 In a comparison with insulin glargine, both treatments reduced HbA1c by 1.1%, and exenatide produced a 2.3 kg weight loss compared with a ...
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80 Januvia side effects and how to avoid them - SingleCare
https://www.singlecare.com/blog/januvia-side-effects/
Januvia should be used along with diet and exercise. Sitagliptin belongs to a family of drugs called dipeptidyl peptidase-4 inhibitors ...
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81 Effect of Noninsulin Antidiabetic Drugs Added to Metformin ...
https://jamanetwork.com/journals/jama/fullarticle/185654
Thiazolidinediones likely promote weight gain by increasing fluid retention. ... Glucagon-like peptide-1 analogs, AGIs, and DPP-4 inhibitors ...
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82 A Clinical Overview of DPP-4 Inhibitors for Type 2 Diabetes
https://journalce.powerpak.com/ce/a-clinical-overview-of-dpp
This lack of effect on weight constitutes an advantage of DPP-4 inhibitors over older oral anti-hyperglycemic medications that typically cause a ...
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83 Key Considerations in use of SGLT2 Inhibitors and GLP-1RAs ...
https://www.acc.org/CVDinDMClinicianTool
pathway on novel therapies for cardiovascular risk reduction in patients with type 2 ... o Weight loss ... Discontinue DPP-4 inhibitor before starting.
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84 DPP-4 Inhibitors (Gliptins) Drugs List - Canadian Insulin
https://canadianinsulin.com/articles/can-expect-taking-dpp-4-inhibitors/
Along with a healthy diet and exercise plan, DPP-4 drugs can be taken on their own or as part of a combination pill to regulate blood sugar.
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85 Will You Need Medication For Weight Loss If You Have ...
https://www.healthcentral.com/article/will-you-need-medication-for-weight-loss-if-you-have-diabetes
“The GLP-1 receptor agonists and the SGLT2 inhibitors do result in weight loss,” Ray said. These two drug classes are recommended in the ...
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86 Weight Reduction Clinical Trial Data - TRIJARDY® XR Tablets
https://www.trijardyxrhcp.com/weight-reduction-data
FOR ADULTS WITH TYPE 2 DIABETES, ALONG WITH DIET AND EXERCISE ... DPP-4i=dipeptidyl peptidase-4 inhibitor; SGLT2i=sodium glucose co-transporter-2 inhibitor; ...
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87 DPP-4 inhibition resembles exercise in preventing type 2 ...
https://journals.sagepub.com/doi/10.1177/0300060520934635
Glucose homeostasis maintenance by DPP-4 inhibitors is at least partially ... DPP-4 inhibition prevented diet-induced hepatic steatosis.
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88 Diabetes Myth Buster: DPP4 Inhibitors vs GLP-1 Agonists
https://www.hmpgloballearningnetwork.com/site/pln/blogs/pln/susan-cornell-pharmd-cde-fapha-faade/november-26-2013/diabetes-myth-buster-dpp4-inhibitors
Weight loss is often observed in patients taking GLP-1 agonists; an adverse drug effect, especially beneficial for overweight or obese T2D ...
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89 Will new treatments lead to novel weight loss drugs?
https://www.sbpdiscovery.org/news/beaker-blog/diabetes-story-will-new-treatments-lead-to-novel-weight-loss-drugs
› news › beaker-blog › d...
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90 Treatment of type 2 diabetes, lifestyle, GLP1 agonists and ...
https://www.wjgnet.com/1948-9358/full/v5/i5/636.htm
As a second line treatment DPP-4 inhibitors achieved a smaller decline in HbA1c than the other hypoglycaemic drugs. There was however, no ...
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91 Drugs for diabetes: part 5 DPP-4 inhibitors
https://bjcardio.co.uk/2011/06/drugs-for-diabetes-part-5-dpp-4-inhibitors/
In clinical practice they are associated with significant reductions in HbA1c, no weight gain and a low risk of hypoglycaemia. Initial cardiovascular safety ...
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92 Treatment of diabetes with DPP4 inhibitors
https://diabeteson.com/treatment-diabetes-dpp4-inhibitors/
When treated with DPP4 inhibitors alone, it is observed that HbA1c falls on average by 5-10 mmol/mol. These drugs are often combined with other ...
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93 Long-Term Weight Loss With Metformin or Lifestyle ...
https://www.acpjournals.org/doi/10.7326/M18-1605
The DPP and the DPPOS make up the largest and longest clinical trial of metformin for prevention of T2D. In the DPP, weight loss explained 64% ...
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94 List of Common Diabetes Medications - Healthline
https://www.healthline.com/health/diabetes/medications-list
DPP-4 inhibitors are used to help reduce blood sugar without causing hypoglycemia. ... to a diet and exercise plan to help promote better glycemic control.
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95 Dipeptidyl peptidase-4 (DPP-4) inhibitors: Nursing ... - Osmosis
https://www.osmosis.org/learn/Oral_antidiabetic_medications_-_Dipeptidyl_peptidase-4_(DPP-4)_inhibitors:_Nursing_Pharmacology
As a result, DPP4 inhibitors increase the levels of incretin, which in turn increases insulin secretion and decreases glucagon secretion. The end result is a ...
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96 Diabetes: Types, Risk Factors, Symptoms, Tests, Treatments ...
https://my.clevelandclinic.org/health/diseases/7104-diabetes-mellitus-an-overview
Work with your healthcare team to develop a weight-loss plan. ... DPP-4 inhibitors (also called dipeptidyl peptidase-4 inhibitors): These ...
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97 Overweight people lost 35 to 52 pounds on newly approved ...
https://www.cnn.com/2022/06/06/health/weight-loss-drug-diabetes-wellness/index.html
Participants who got a placebo lost between 2.4% and 3.1% of their body weight, on average. In comparison, studies on people with diabetes who ...
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98 Questions and Answers About Choosing Antihyperglycemic ...
https://dxlink.ca/CJDX/2018/May/T2DM_Add-on_Therapy.php
The DPP-4 inhibitor class has demonstrated in several different studies that the expected reduction in A1C is not markedly different for older or younger adults ...
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