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1
Immune Response to Mycobacterium tuberculosis: A Narrative ...
https://www.frontiersin.org/articles/10.3389/fped.2019.00350/full
The immune response of T lymphocytes begins at the moment that Mtb spreads inside the lymph nodes but its arousal lays in the early activation ...
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https://www.frontiersin.org/articles/10.3389/fped.2019.00350/full
The immune response of T lymphocytes begins at the moment that Mtb spreads inside the lymph nodes but its arousal lays in the early activation ...
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2
Immune Response to Mycobacterium tuberculosis: A ... - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718705/
The immune response of T lymphocytes begins at the moment that Mtb spreads inside the lymph nodes but its arousal lays in the early activation ...
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718705/
The immune response of T lymphocytes begins at the moment that Mtb spreads inside the lymph nodes but its arousal lays in the early activation ...
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3
Innate immunity in tuberculosis: host defense vs pathogen ...
https://www.nature.com/articles/cmi201788
Most often, bacterial replication is contained, and the inflammatory response subsides, leading to latent TB. Individuals with latent TB have an ...
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https://www.nature.com/articles/cmi201788
Most often, bacterial replication is contained, and the inflammatory response subsides, leading to latent TB. Individuals with latent TB have an ...
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4
Immunology of tuberculosis - UpToDate
https://www.uptodate.com/contents/immunology-of-tuberculosis
Innate immunity — The pathophysiology of innate immune response during first encounter of M. tuberculosis with lung cells remains poorly ...
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https://www.uptodate.com/contents/immunology-of-tuberculosis
Innate immunity — The pathophysiology of innate immune response during first encounter of M. tuberculosis with lung cells remains poorly ...
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5
To fight TB infection, early protection is crucial
https://medicine.wustl.edu/news/early-protection-against-tb-crucial-to-fighting-infection/
In the first days after the tuberculosis (TB) bacteria infect the body, a flurry of immune cells are activated to fight the infection.
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https://medicine.wustl.edu/news/early-protection-against-tb-crucial-to-fighting-infection/
In the first days after the tuberculosis (TB) bacteria infect the body, a flurry of immune cells are activated to fight the infection.
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6
How the tuberculosis bacterium tricks the immune system
https://www.sciencedaily.com/releases/2015/06/150602130414.htm
tuberculosis carries out a subtle assault on our immune defenses. The key is a molecule called cGAS, which is found in the lung's macrophages, ...
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https://www.sciencedaily.com/releases/2015/06/150602130414.htm
tuberculosis carries out a subtle assault on our immune defenses. The key is a molecule called cGAS, which is found in the lung's macrophages, ...
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7
Mycobacterium tuberculosis inhibits human innate immune ...
https://www.pnas.org/doi/10.1073/pnas.1707840114
Mycobacterium tuberculosis is a major human pathogen that is able to survive inside host cells and resist immune clearance. Most particularly, ...
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https://www.pnas.org/doi/10.1073/pnas.1707840114
Mycobacterium tuberculosis is a major human pathogen that is able to survive inside host cells and resist immune clearance. Most particularly, ...
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8
The Host Immune Response to Tuberculosis - ATS Journals
https://www.atsjournals.org/doi/full/10.1164/ajrccm.157.3.9708002
by NW SCHLUGER · 1998 · Cited by 659 —
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https://www.atsjournals.org/doi/full/10.1164/ajrccm.157.3.9708002
by NW SCHLUGER · 1998 · Cited by 659 —
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9
The Immune Response to Mycobacterium tuberculosis ...
https://www.intechopen.com/chapters/43706
Active TB patients, as well as latently infected carriers, do not suffer from a general innate or adaptive immune defect. On the contrary, ex-vivo studies of ...
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https://www.intechopen.com/chapters/43706
Active TB patients, as well as latently infected carriers, do not suffer from a general innate or adaptive immune defect. On the contrary, ex-vivo studies of ...
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10
The Innate Immune Response to Mycobacterium tuberculosis ...
https://www.annualreviews.org/doi/abs/10.1146/annurev-immunol-093019-010426
Infection with Mycobacterium tuberculosis causes >1.5 million deaths worldwide annually. Innate immune cells are the first to encounter M. tuberculosis, ...
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https://www.annualreviews.org/doi/abs/10.1146/annurev-immunol-093019-010426
Infection with Mycobacterium tuberculosis causes >1.5 million deaths worldwide annually. Innate immune cells are the first to encounter M. tuberculosis, ...
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11
Interconnection of Mycobacterium tuberculosis with host ...
https://www.oatext.com/interconnection-of-mycobacterium-tuberculosis-with-host-immune-system.php
Acquired cellular immune response during MTB infection is widely accepted to consist of T-cells (CD4) and mononuclear phagocytes [43]. Granuloma formation is ...
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https://www.oatext.com/interconnection-of-mycobacterium-tuberculosis-with-host-immune-system.php
Acquired cellular immune response during MTB infection is widely accepted to consist of T-cells (CD4) and mononuclear phagocytes [43]. Granuloma formation is ...
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12
The innate immune response in human tuberculosis - 2015
https://onlinelibrary.wiley.com/doi/10.1111/cmi.12480
Mycobacterium tuberculosis (Mtb) infection can be cleared by the innate immune system before the initiation of an adaptive immune response.
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https://onlinelibrary.wiley.com/doi/10.1111/cmi.12480
Mycobacterium tuberculosis (Mtb) infection can be cleared by the innate immune system before the initiation of an adaptive immune response.
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13
Innate Immune Defenses in Human Tuberculosis - Hindawi
https://www.hindawi.com/journals/jir/2015/747543/
Human alveolar macrophages possess an array of receptors to recognize M. tuberculosis (Mtb). In response to Mtb infection, macrophages upregulate effector and ...
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https://www.hindawi.com/journals/jir/2015/747543/
Human alveolar macrophages possess an array of receptors to recognize M. tuberculosis (Mtb). In response to Mtb infection, macrophages upregulate effector and ...
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14
Stealth Strategies of Mycobacterium tuberculosis for Immune ...
https://www.mdpi.com/1467-3045/41/1/12/pdf
tb successfully manipulate these responses of the innate and adaptive immune system of host for its persistence is questionable till date? Similar to our ...
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https://www.mdpi.com/1467-3045/41/1/12/pdf
tb successfully manipulate these responses of the innate and adaptive immune system of host for its persistence is questionable till date? Similar to our ...
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15
Pulmonary innate immunity during Mycobacterium ... - YouTube
https://www.youtube.com/watch?v=7HsrxoMQLBM
GLOBAL IMMUNOTALKS
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https://www.youtube.com/watch?v=7HsrxoMQLBM
GLOBAL IMMUNOTALKS
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16
3. Immunity to TB - Immunopaedia
https://www.immunopaedia.org.za/immunology/special-focus-area/3-immunity-to-tb/
Mycobacterium tuberculosis is the causative bacterium of tuberculosis or TB infections. The mycobacterium infects the body and evades parts of the immune ...
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https://www.immunopaedia.org.za/immunology/special-focus-area/3-immunity-to-tb/
Mycobacterium tuberculosis is the causative bacterium of tuberculosis or TB infections. The mycobacterium infects the body and evades parts of the immune ...
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17
New study uncovers the dynamics of adaptive immunity in ...
https://www.drugtargetreview.com/news/103197/new-study-uncovers-the-dynamics-of-adaptive-immunity-in-tuberculosis/
Unlike other infectious diseases that affect the lungs, the immune response to fight tuberculosis (TB) infections develops at least twice as ...
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https://www.drugtargetreview.com/news/103197/new-study-uncovers-the-dynamics-of-adaptive-immunity-in-tuberculosis/
Unlike other infectious diseases that affect the lungs, the immune response to fight tuberculosis (TB) infections develops at least twice as ...
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18
How Tuberculosis Flies Under the Radar of Our Immune System
https://norgenbiotek.com/blog/how-tuberculosis-flies-under-radar-our-immune-system
Mycobacterium tuberculosis (M.tb) invades our body by attacking a subset of white blood cells called macrophages. Macrophages have a central ...
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https://norgenbiotek.com/blog/how-tuberculosis-flies-under-radar-our-immune-system
Mycobacterium tuberculosis (M.tb) invades our body by attacking a subset of white blood cells called macrophages. Macrophages have a central ...
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19
Review Innate immunity in tuberculosis: how the sensing of ...
https://www.sciencedirect.com/science/article/pii/S1286457915001872
The hallmark of TB reactivation is the failure of the host immune response to restrain the bacterial growth, inducing new rounds of macrophage necrotic death ...
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https://www.sciencedirect.com/science/article/pii/S1286457915001872
The hallmark of TB reactivation is the failure of the host immune response to restrain the bacterial growth, inducing new rounds of macrophage necrotic death ...
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20
LTBI: latent tuberculosis infection or lasting immune ...
https://erj.ersjournals.com/content/33/5/956
tuberculosis has earlier been lodged after haematogenous dissemination. Consequently, T-cells encounter an increased antigenic load that precipitates a ...
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https://erj.ersjournals.com/content/33/5/956
tuberculosis has earlier been lodged after haematogenous dissemination. Consequently, T-cells encounter an increased antigenic load that precipitates a ...
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21
Chapter 2 Transmission and Pathogenesis of Tuberculosis
https://www.cdc.gov/tb/education/corecurr/pdf/chapter2.pdf
process of dissemination primes the immune system for a systemic response. Further details about pathogenesis of latent tuberculosis infection (LTBI) and TB ...
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https://www.cdc.gov/tb/education/corecurr/pdf/chapter2.pdf
process of dissemination primes the immune system for a systemic response. Further details about pathogenesis of latent tuberculosis infection (LTBI) and TB ...
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22
Human Pulmonary Tuberculosis: Understanding the Immune ...
https://mdpi-res.com/d_attachment/biomolecules/biomolecules-12-01148/article_deploy/biomolecules-12-01148.pdf?version=1660979504
Response in the Bronchoalveolar System. María Teresa Herrera 1 ... M. tuberculosis Complex and Its Influence on the Immune Response.
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https://mdpi-res.com/d_attachment/biomolecules/biomolecules-12-01148/article_deploy/biomolecules-12-01148.pdf?version=1660979504
Response in the Bronchoalveolar System. María Teresa Herrera 1 ... M. tuberculosis Complex and Its Influence on the Immune Response.
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23
Delayed Adaptive Immune Response to Tuberculosis Points ...
https://www.genengnews.com/topics/translational-medicine/infectious-diseases/delayed-adaptive-immune-response-to-tuberculosis-points-to-vaccination-strategies/
The immune response against tuberculosis (TB) infections develops at least twice as slowly as that triggered by other infectious diseases ...
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https://www.genengnews.com/topics/translational-medicine/infectious-diseases/delayed-adaptive-immune-response-to-tuberculosis-points-to-vaccination-strategies/
The immune response against tuberculosis (TB) infections develops at least twice as slowly as that triggered by other infectious diseases ...
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24
Local Immune Responses in Human Tuberculosis
https://academic.oup.com/jid/article/205/suppl_2/S316/805643
A shift in the local immune response will tip the balance toward suboptimal immunity and impaired control of tuberculosis disease but can also ...
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https://academic.oup.com/jid/article/205/suppl_2/S316/805643
A shift in the local immune response will tip the balance toward suboptimal immunity and impaired control of tuberculosis disease but can also ...
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25
Pitt Researchers Uncover Dynamics of Adaptive Immunity in ...
https://www.upmc.com/media/news/051722-flynn
PITTSBURGH – Unlike other infectious diseases that affect the lungs, the immune response to fight tuberculosis (TB) infections develops at ...
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https://www.upmc.com/media/news/051722-flynn
PITTSBURGH – Unlike other infectious diseases that affect the lungs, the immune response to fight tuberculosis (TB) infections develops at ...
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26
Initiation of the adaptive immune response to Mycobacterium ...
https://rupress.org/jem/article/205/1/105/47087/Initiation-of-the-adaptive-immune-response-to
Protective immunity to tuberculosis depends on CD4+ T lymphocytes in humans and in mice (1, 2), but adaptive immune responses are unable to eradicate ...
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https://rupress.org/jem/article/205/1/105/47087/Initiation-of-the-adaptive-immune-response-to
Protective immunity to tuberculosis depends on CD4+ T lymphocytes in humans and in mice (1, 2), but adaptive immune responses are unable to eradicate ...
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27
Manipulation and exploitation of host immune system by ...
https://www.futuremedicine.com/doi/abs/10.2217/fmb-2022-0026
Mycobacterium tuberculosis (Mtb) can become a long-term infection by evading the host immune response. Coevolution of Mtb with humans has ...
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https://www.futuremedicine.com/doi/abs/10.2217/fmb-2022-0026
Mycobacterium tuberculosis (Mtb) can become a long-term infection by evading the host immune response. Coevolution of Mtb with humans has ...
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28
Cellular and Humoral Immune Responses During ...
https://www.jrheum.org/content/91/17
Mycobacterium tuberculosis (Mtb) infection is a major public health problem. A large body of evidence indicates that the immune system plays ...
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https://www.jrheum.org/content/91/17
Mycobacterium tuberculosis (Mtb) infection is a major public health problem. A large body of evidence indicates that the immune system plays ...
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29
Tuberculosis: Different types of immunity determine the course ...
https://www.dzif.de/en/tuberculosis-different-types-of-immunity-determine-course-of-disease
An international research team has succeeded in characterising different immune responses of tuberculosis patients and identifying groups of ...
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https://www.dzif.de/en/tuberculosis-different-types-of-immunity-determine-course-of-disease
An international research team has succeeded in characterising different immune responses of tuberculosis patients and identifying groups of ...
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30
The Inflammatory Response in Mycobacterium Tuberculosis ...
https://link.springer.com/chapter/10.1007/978-94-015-9702-9_11
Infection with Mycobacterium tuberculosis (MTB) is accompanied by an intense local inflammatory response which may be critical to the pathogenesis of ...
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https://link.springer.com/chapter/10.1007/978-94-015-9702-9_11
Infection with Mycobacterium tuberculosis (MTB) is accompanied by an intense local inflammatory response which may be critical to the pathogenesis of ...
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31
HIV and the tuberculosis “set point”: how HIV impairs alveolar ...
https://retrovirology.biomedcentral.com/articles/10.1186/s12977-020-00540-2
This early immune response is impaired in the context of HIV coinfection, allowing for a higher mycobacterial set point and greater likelihood ...
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https://retrovirology.biomedcentral.com/articles/10.1186/s12977-020-00540-2
This early immune response is impaired in the context of HIV coinfection, allowing for a higher mycobacterial set point and greater likelihood ...
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32
Delayed T cell Response Allows Tuberculosis to Gain ...
https://www.the-scientist.com/news-opinion/delayed-t-cell-response-allows-tuberculosis-to-gain-foothold-in-monkeys-70083
After a host inhales Mtb, previous research has found that the immune system typically responds by deploying cells such as macrophages and T ...
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https://www.the-scientist.com/news-opinion/delayed-t-cell-response-allows-tuberculosis-to-gain-foothold-in-monkeys-70083
After a host inhales Mtb, previous research has found that the immune system typically responds by deploying cells such as macrophages and T ...
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33
Evasion of the immune system by Mycobacterium tuberculosis
https://www.medigraphic.com/cgi-bin/new/resumenI.cgi?IDARTICULO=81000
Objectives: to describe the different molecular mechanisms by which Mycobacterium tuberculosis is able to evade the immune response of the host and ...
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https://www.medigraphic.com/cgi-bin/new/resumenI.cgi?IDARTICULO=81000
Objectives: to describe the different molecular mechanisms by which Mycobacterium tuberculosis is able to evade the immune response of the host and ...
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34
immune responses against mycobacterium tuberculosis ...
https://openarchive.ki.se/xmlui/bitstream/handle/10616/42090/Thesis_Nancy_Montserrat_Alvarez_Corrales.pdf?sequence=4&isAllowed=y
The antigen specific, adaptive immune response execute several effectors functions via the activation of components of the innate immune system[11]. Early lines ...
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https://openarchive.ki.se/xmlui/bitstream/handle/10616/42090/Thesis_Nancy_Montserrat_Alvarez_Corrales.pdf?sequence=4&isAllowed=y
The antigen specific, adaptive immune response execute several effectors functions via the activation of components of the innate immune system[11]. Early lines ...
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35
TB bacterium may suppress immune system to spread disease
https://www.medicalnewstoday.com/articles/317745
“Tuberculosis has co-evolved with humans to become an ultimate pathogen, and we identify a mechanism whereby the bacteria disables the 'brakes' ...
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https://www.medicalnewstoday.com/articles/317745
“Tuberculosis has co-evolved with humans to become an ultimate pathogen, and we identify a mechanism whereby the bacteria disables the 'brakes' ...
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36
Immune correlates of Mycobacterium Tuberculosis patients in ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0262454
The Immune response in TB patients is distinguishable by the HIV status. The study suggests that HIV-negative TB patients unlike PLHIV ...
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0262454
The Immune response in TB patients is distinguishable by the HIV status. The study suggests that HIV-negative TB patients unlike PLHIV ...
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37
Tuberculosis - La Jolla Institute for Immunology
https://www.lji.org/diseases/tuberculosis/
Some people who contract TB mount a successful immune response that clears the infection. In others, however, the disease remains in a latent state—held in ...
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https://www.lji.org/diseases/tuberculosis/
Some people who contract TB mount a successful immune response that clears the infection. In others, however, the disease remains in a latent state—held in ...
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38
VapBC22 toxin-antitoxin system from Mycobacterium ...
https://www.science.org/doi/10.1126/sciadv.aba6944
tuberculosis results in reduced levels of metabolic enzymes and increased levels of ribosomal proteins. Proteomics studies showed reduced expression of ...
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https://www.science.org/doi/10.1126/sciadv.aba6944
tuberculosis results in reduced levels of metabolic enzymes and increased levels of ribosomal proteins. Proteomics studies showed reduced expression of ...
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39
Profiling the immune response to Mycobacterium tuberculosis ...
https://www.tandfonline.com/doi/full/10.1080/21505594.2021.1936432
The pathogenic mechanism and immune response against this pathogen is unknown. Thus, we compared the course of pulmonary TB in BALB/c mice infected with ...
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https://www.tandfonline.com/doi/full/10.1080/21505594.2021.1936432
The pathogenic mechanism and immune response against this pathogen is unknown. Thus, we compared the course of pulmonary TB in BALB/c mice infected with ...
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40
Innate immune responses to Mycobacterium tuberculosis ...
https://www.researchgate.net/publication/347517398_Innate_immune_responses_to_Mycobacterium_tuberculosis_infection_How_extracellular_traps_and_trained_immunity_can_restrict_bacterial_growth
neutrophils and macrophages respond to a mycobacterial infection and can control M. tuberculosis-replication. Neutrophils and macrophages can ...
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https://www.researchgate.net/publication/347517398_Innate_immune_responses_to_Mycobacterium_tuberculosis_infection_How_extracellular_traps_and_trained_immunity_can_restrict_bacterial_growth
neutrophils and macrophages respond to a mycobacterial infection and can control M. tuberculosis-replication. Neutrophils and macrophages can ...
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41
What Happens When the Immune System Does Not Work ...
https://www.chop.edu/centers-programs/vaccine-education-center/human-immune-system/what-happens-when-immune-system-does-not-work-properly
› vaccine-education-center › wha...
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https://www.chop.edu/centers-programs/vaccine-education-center/human-immune-system/what-happens-when-immune-system-does-not-work-properly
› vaccine-education-center › wha...
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42
Immune recognition and innate response in bovine tuberculosis
https://www.visavet.es/en/articles/immune-recognition-innate-response-bovine-tuberculosis.php
tuberculosis complex (not only by M. bovis). Innate response begins after the infection and before the initiation of adaptive immunity. The ...
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https://www.visavet.es/en/articles/immune-recognition-innate-response-bovine-tuberculosis.php
tuberculosis complex (not only by M. bovis). Innate response begins after the infection and before the initiation of adaptive immunity. The ...
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43
Immune factors and immunoregulation in tuberculosis - SciELO
https://www.scielo.br/j/bjmbr/a/q65kjjFFFb5k5QVQc86w9kf/?lang=en
In cases of latent TB, the host mounts a strong immune response, which contains but does not eliminate the infection. Failure of immune resistance mechanisms ...
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https://www.scielo.br/j/bjmbr/a/q65kjjFFFb5k5QVQc86w9kf/?lang=en
In cases of latent TB, the host mounts a strong immune response, which contains but does not eliminate the infection. Failure of immune resistance mechanisms ...
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44
A CD4+ TNF+ monofunctional memory T-cell response to ...
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00207-9/fulltext
The immunologic correlates of risk of Mycobacterium tuberculosis (Mtb) infection after BCG vaccination are unknown.
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https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00207-9/fulltext
The immunologic correlates of risk of Mycobacterium tuberculosis (Mtb) infection after BCG vaccination are unknown.
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45
Dynamics of adaptive immunity in tuberculosis uncovered
https://www.eurekalert.org/news-releases/952800
PITTSBURGH, May 17, 2022 – Unlike other infectious diseases that affect the lungs, the immune response to fight tuberculosis (TB) infections ...
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https://www.eurekalert.org/news-releases/952800
PITTSBURGH, May 17, 2022 – Unlike other infectious diseases that affect the lungs, the immune response to fight tuberculosis (TB) infections ...
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46
Innate immune receptors in development of Mycobacterium ...
https://iimmun.ru/iimm/article/view/1169
Significance of innate mucosal factors in implementing immune response to M. tuberculosis is discussed. In particular, Toll-like receptors, ...
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https://iimmun.ru/iimm/article/view/1169
Significance of innate mucosal factors in implementing immune response to M. tuberculosis is discussed. In particular, Toll-like receptors, ...
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47
Immune evasion and provocation by Mycobacterium ...
https://redetb.org.br/immune-evasion-and-provocation-by-mycobacterium-tuberculosis/
M. tuberculosis is well adapted to establish infection, persist in the face of the host immune response and be transmitted to uninfected individuals.
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https://redetb.org.br/immune-evasion-and-provocation-by-mycobacterium-tuberculosis/
M. tuberculosis is well adapted to establish infection, persist in the face of the host immune response and be transmitted to uninfected individuals.
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48
Tuberculosis - World Health Organization (WHO)
https://www.who.int/health-topics/tuberculosis
People infected with TB bacteria have a 5–10% lifetime risk of falling ill with TB. Those with compromised immune systems, such as people living with HIV, ...
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https://www.who.int/health-topics/tuberculosis
People infected with TB bacteria have a 5–10% lifetime risk of falling ill with TB. Those with compromised immune systems, such as people living with HIV, ...
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49
How TB infects the body: The Tubercle - TB Online
https://www.tbonline.info/posts/2016/3/31/how-tb-infects-body-tubercle-1/
After the bacillus reaches the alveoli in the lung, it gets picked up by special cells of the immune system, called macrophages. These ...
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https://www.tbonline.info/posts/2016/3/31/how-tb-infects-body-tubercle-1/
After the bacillus reaches the alveoli in the lung, it gets picked up by special cells of the immune system, called macrophages. These ...
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50
Immune Response to Mycobacterium Tuberculosis Infection
https://www.clinicaltrials.gov/ct2/show/NCT00257907
This study will examine how the immune system responds to infection with Mycobacterium tuberculosis bacteria (bacteria that cause tuberculosis) in order to ...
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https://www.clinicaltrials.gov/ct2/show/NCT00257907
This study will examine how the immune system responds to infection with Mycobacterium tuberculosis bacteria (bacteria that cause tuberculosis) in order to ...
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51
Targeting innate immunity for tuberculosis vaccination - JCI
https://www.jci.org/articles/view/128877
Memory B and T cells initiate a rapid and robust immune response upon encounter with Mycobacterium tuberculosis, thus achieving long-lasting ...
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https://www.jci.org/articles/view/128877
Memory B and T cells initiate a rapid and robust immune response upon encounter with Mycobacterium tuberculosis, thus achieving long-lasting ...
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52
Tuberculosis Pathogenesis - Immunology/Microbiology ...
https://www.drawittoknowit.com/course/immunology/glossary/immunology-microbiology/tuberculosis-pathogenesis
Mycobacterium tuberculosis has evolved to highjack the innate immune response and to delay the adaptive immune response.
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https://www.drawittoknowit.com/course/immunology/glossary/immunology-microbiology/tuberculosis-pathogenesis
Mycobacterium tuberculosis has evolved to highjack the innate immune response and to delay the adaptive immune response.
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53
The Human-Tuberculosis Arms Race - Science in the News
https://sitn.hms.harvard.edu/flash/2022/the-human-tuberculosis-arms-race/
As new COVID-19 variants keep emerging, we can observe the evolution of the virus in response to vaccines and human immune systems.
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https://sitn.hms.harvard.edu/flash/2022/the-human-tuberculosis-arms-race/
As new COVID-19 variants keep emerging, we can observe the evolution of the virus in response to vaccines and human immune systems.
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54
New details behind the body's response to tuberculosis could ...
https://ragoninstitute.org/latest-news/new-details-behind-the-bodys-response-to-tuberculosis-could-lead-to-a-more-effective-vaccine/
New research has identified helpful and unhelpful aspects of the immune response that determine whether the body can keep TB infections ...
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https://ragoninstitute.org/latest-news/new-details-behind-the-bodys-response-to-tuberculosis-could-lead-to-a-more-effective-vaccine/
New research has identified helpful and unhelpful aspects of the immune response that determine whether the body can keep TB infections ...
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55
Tuberculosis Is Associated with a Down-Modulatory Lung ...
https://www.jimmunol.org/content/183/1/718
Another study showed that immune responses to liparabinomannan, the M. tuberculosis cell wall component, appeared to be mediated by IL-1 ...
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https://www.jimmunol.org/content/183/1/718
Another study showed that immune responses to liparabinomannan, the M. tuberculosis cell wall component, appeared to be mediated by IL-1 ...
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56
The Curcumin Effects on Immune-Response and Its Potential ...
https://www.jsmcentral.org/ClinicalCytology/jsmccp592925.php
Mycobacterium tuberculosis is commonly entered to the human body via inhalation of infected droplets from smearpositive TB individuals; innate immunity such as ...
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https://www.jsmcentral.org/ClinicalCytology/jsmccp592925.php
Mycobacterium tuberculosis is commonly entered to the human body via inhalation of infected droplets from smearpositive TB individuals; innate immunity such as ...
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57
General Questions About Tuberculosis (TB)
https://www.health.nd.gov/tb/about
Some people develop TB disease soon (within weeks) after becoming infected, before their immune system can fight the TB bacteria. Other people may get sick ...
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https://www.health.nd.gov/tb/about
Some people develop TB disease soon (within weeks) after becoming infected, before their immune system can fight the TB bacteria. Other people may get sick ...
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58
Tuberculosis (TB) - NHS inform
https://www.nhsinform.scot/illnesses-and-conditions/infections-and-poisoning/tuberculosis-tb
Latent TB could develop into an active TB infection at a later date, particularly if your immune system becomes weakened.
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https://www.nhsinform.scot/illnesses-and-conditions/infections-and-poisoning/tuberculosis-tb
Latent TB could develop into an active TB infection at a later date, particularly if your immune system becomes weakened.
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59
Alveolar macrophages up-regulate a non-classical innate ...
https://www.biorxiv.org/content/10.1101/520791v1.full
Alveolar macrophages (AMs) are the first cells to be infected during Mycobacterium tuberculosis (Mtb) infection. Thus the AM response to ...
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https://www.biorxiv.org/content/10.1101/520791v1.full
Alveolar macrophages (AMs) are the first cells to be infected during Mycobacterium tuberculosis (Mtb) infection. Thus the AM response to ...
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60
Cancer drugs might be able to target tuberculosis, study finds
https://med.stanford.edu/news/all-news/2022/03/cancer-drugs-tuberculosis.html
Tuberculosis lesions in the lungs have high levels of proteins that suppress the immune system. Cancer drugs that target these proteins ...
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https://med.stanford.edu/news/all-news/2022/03/cancer-drugs-tuberculosis.html
Tuberculosis lesions in the lungs have high levels of proteins that suppress the immune system. Cancer drugs that target these proteins ...
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61
Role of neutrophils in tuberculosis: A bird's eye view
https://journals.sagepub.com/doi/full/10.1177/1753425919881176
Neutrophilia in TB has been shown to be independently associated with increased risk of mortality. ... Neutrophils which remain crucial immune responders during ...
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https://journals.sagepub.com/doi/full/10.1177/1753425919881176
Neutrophilia in TB has been shown to be independently associated with increased risk of mortality. ... Neutrophils which remain crucial immune responders during ...
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62
How does our immune system respond to different stages of ...
https://researchmatters.in/news/how-does-our-immune-system-respond-different-stages-tuberculosis
Tuberculosis (TB), caused by the notorious bacteria Mycobacterium tuberculosis, is a deadly disease that kills millions each year across the ...
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https://researchmatters.in/news/how-does-our-immune-system-respond-different-stages-tuberculosis
Tuberculosis (TB), caused by the notorious bacteria Mycobacterium tuberculosis, is a deadly disease that kills millions each year across the ...
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63
Host immune responses to mycobacterial antigens and their ...
https://ecevr.org/Synapse/Data/PDFData/9995CEVR/cevr-3-155.pdf
A schematic diagram of host immune system against infection of Mycobacterium tuberculosis (Mtb). Mtb is inhaled by aerosols and transmitted to the lungs, where ...
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https://ecevr.org/Synapse/Data/PDFData/9995CEVR/cevr-3-155.pdf
A schematic diagram of host immune system against infection of Mycobacterium tuberculosis (Mtb). Mtb is inhaled by aerosols and transmitted to the lungs, where ...
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64
Multidimensional analysis of immune response identified ...
https://www.medrxiv.org/content/10.1101/2021.01.27.21250605v1.full
The risk of tuberculosis (TB) disease is higher in individuals with recent Mycobacterium tuberculosis (M.tb) infection compared to individuals ...
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https://www.medrxiv.org/content/10.1101/2021.01.27.21250605v1.full
The risk of tuberculosis (TB) disease is higher in individuals with recent Mycobacterium tuberculosis (M.tb) infection compared to individuals ...
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65
Tuberculosis virulence factor identified, may be target for new ...
https://www.purdue.edu/newsroom/releases/2016/Q4/tuberculosis-virulence-factor-identified,-may-be-target-for-new-drug.html
Scientists have discovered the mechanism that hijacks the immune system's response to tuberculosis, revealing an important new drug target ...
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https://www.purdue.edu/newsroom/releases/2016/Q4/tuberculosis-virulence-factor-identified,-may-be-target-for-new-drug.html
Scientists have discovered the mechanism that hijacks the immune system's response to tuberculosis, revealing an important new drug target ...
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66
Blocking the spread of HIV or favouring the spread ... - IrsiCaixa
https://www.irsicaixa.es/en/news/blocking-spread-hiv-or-favouring-spread-tuberculosis-bacteria-flip-side-siglec-1-proteins
HIV infects the immune system's cells, specifically CD4+ T cells. ... other cells of the immune system, so the immune response against Mtb ...
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https://www.irsicaixa.es/en/news/blocking-spread-hiv-or-favouring-spread-tuberculosis-bacteria-flip-side-siglec-1-proteins
HIV infects the immune system's cells, specifically CD4+ T cells. ... other cells of the immune system, so the immune response against Mtb ...
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67
Killer disease: How the body reacts to tuberculosis - MSF UK
https://msf.org.uk/video/killer-disease-how-body-reacts-tuberculosis
Médecins Sans Frontières/Doctors Without Borders
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https://msf.org.uk/video/killer-disease-how-body-reacts-tuberculosis
Médecins Sans Frontières/Doctors Without Borders
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68
Researchers Identify Immune Response to Tuberculosis ...
https://www.newswise.com/articles/researchers-identify-immune-response-to-tuberculosis-infection
T cells with innate immunity, including the gamma delta T cells, function as the immune system's "first line of defense" against foreign ...
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https://www.newswise.com/articles/researchers-identify-immune-response-to-tuberculosis-infection
T cells with innate immunity, including the gamma delta T cells, function as the immune system's "first line of defense" against foreign ...
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69
Changed immune and miRNA response in RAW264.7 cells ...
https://www.spandidos-publications.com/10.3892/ijmm.2018.3471
Cell wall deficient (CWD) forms of Mycobacterium tuberculosis (Mtb) confers a marked resistance to immune system of the host.
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https://www.spandidos-publications.com/10.3892/ijmm.2018.3471
Cell wall deficient (CWD) forms of Mycobacterium tuberculosis (Mtb) confers a marked resistance to immune system of the host.
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70
The immune response in tuberculosis. | Semantic Scholar
https://www.semanticscholar.org/paper/The-immune-response-in-tuberculosis.-O%E2%80%99Garra-Redford/572fa47296aa93c936511f8b0ff7e571aa20ae86
Immune Responses Involved in Mycobacterium Tuberculosis Infection · Granulomatous Response to Mycobacterium tuberculosis Infection · Systems ...
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https://www.semanticscholar.org/paper/The-immune-response-in-tuberculosis.-O%E2%80%99Garra-Redford/572fa47296aa93c936511f8b0ff7e571aa20ae86
Immune Responses Involved in Mycobacterium Tuberculosis Infection · Granulomatous Response to Mycobacterium tuberculosis Infection · Systems ...
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71
The fight against TB shifts to fixing the immune system, not ...
https://theconversation.com/the-fight-against-tb-shifts-to-fixing-the-immune-system-not-only-bacteria-56695
Tissue destruction can be the result of an overwhelming inflammation that destroys important cells in the immune system where the infection ...
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https://theconversation.com/the-fight-against-tb-shifts-to-fixing-the-immune-system-not-only-bacteria-56695
Tissue destruction can be the result of an overwhelming inflammation that destroys important cells in the immune system where the infection ...
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72
The Tuberculosis Pathogen Is Captured Infecting a Cell
https://www.labroots.com/trending/microbiology/18370/tuberculosis-pathogen-captured-infecting-cell
Tuberculosis is caused by a bacterium, and it can infect immune cells called macrophages in the lungs that would normally attack pathogenic ...
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https://www.labroots.com/trending/microbiology/18370/tuberculosis-pathogen-captured-infecting-cell
Tuberculosis is caused by a bacterium, and it can infect immune cells called macrophages in the lungs that would normally attack pathogenic ...
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73
The immunology underlying tuberculosis - HSTalks
https://hstalks.com/t/4928/the-immunology-underlying-tuberculosis/
Then to drill down on our understanding currently of the innate immune response and the adaptive immune response to TB.
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https://hstalks.com/t/4928/the-immunology-underlying-tuberculosis/
Then to drill down on our understanding currently of the innate immune response and the adaptive immune response to TB.
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74
Mycobacterium tuberculosis (Tuberculosis) - Osmosis
https://www.osmosis.org/learn/Mycobacterium_tuberculosis_(Tuberculosis)
If and when a person's immune system becomes compromised, like with AIDS or with aging, the Ghon focus can become reactivated, and the infection can spread to ...
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https://www.osmosis.org/learn/Mycobacterium_tuberculosis_(Tuberculosis)
If and when a person's immune system becomes compromised, like with AIDS or with aging, the Ghon focus can become reactivated, and the infection can spread to ...
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75
Tuberculosis (TB) - WebMD
https://www.webmd.com/lung/understanding-tuberculosis-basics
You could be more likely to get TB if: ... A healthy immune system fights the TB bacteria. But you might not be able to fend off active TB disease ...
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https://www.webmd.com/lung/understanding-tuberculosis-basics
You could be more likely to get TB if: ... A healthy immune system fights the TB bacteria. But you might not be able to fend off active TB disease ...
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76
Tuberculosis | Info Centre
https://www.helmholtz-hzi.de/en/info-centre/topics/germs-and-diseases/tuberculosis/
Here you can find out more about the scientific results of the HZI in the research topics ”Bacterial and Viral Pathogens”, “Immune Response and Interventions” ...
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https://www.helmholtz-hzi.de/en/info-centre/topics/germs-and-diseases/tuberculosis/
Here you can find out more about the scientific results of the HZI in the research topics ”Bacterial and Viral Pathogens”, “Immune Response and Interventions” ...
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77
Inflammation: What Is It, Causes, Symptoms & Treatment
https://my.clevelandclinic.org/health/symptoms/21660-inflammation
Inflammation occurs when your immune system sends out cells to fight ... These cells begin an inflammatory response to trap bacteria and ...
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https://my.clevelandclinic.org/health/symptoms/21660-inflammation
Inflammation occurs when your immune system sends out cells to fight ... These cells begin an inflammatory response to trap bacteria and ...
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78
Tuberculosis - Wikipedia
https://en.wikipedia.org/wiki/Tuberculosis
Prognosis · Progression from TB infection to overt TB disease occurs when the bacilli overcome the immune system defenses and begin to multiply. In primary TB ...
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https://en.wikipedia.org/wiki/Tuberculosis
Prognosis · Progression from TB infection to overt TB disease occurs when the bacilli overcome the immune system defenses and begin to multiply. In primary TB ...
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79
Learn About Tuberculosis | American Lung Association
https://www.lung.org/lung-health-diseases/lung-disease-lookup/tuberculosis/learn-about-tuberculosis
Healthy individuals may contract latent TB, but the disease may not become active until months or years later, at a time when the immune system becomes weak ...
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https://www.lung.org/lung-health-diseases/lung-disease-lookup/tuberculosis/learn-about-tuberculosis
Healthy individuals may contract latent TB, but the disease may not become active until months or years later, at a time when the immune system becomes weak ...
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80
Anna Coussens Studies Immune Response to Infection
https://findinggeniuspodcast.libsyn.com/tackling-the-tuberculosis-pandemic-anna-coussens-studies-immune-response-to-infection
She helps listeners understand why Mycobacterium tuberculosis is still the cause of so much illness, explaining the interplay of immunity and ...
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https://findinggeniuspodcast.libsyn.com/tackling-the-tuberculosis-pandemic-anna-coussens-studies-immune-response-to-infection
She helps listeners understand why Mycobacterium tuberculosis is still the cause of so much illness, explaining the interplay of immunity and ...
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81
Mycobacterium tuberculosis-infected human macrophages ...
https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-148-10-3161?crawler=true
... alveolar macrophages, there is spread of bacilli to regional lymph nodes in the lungs and subsequent presentation of antigens to the host immune system.
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https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-148-10-3161?crawler=true
... alveolar macrophages, there is spread of bacilli to regional lymph nodes in the lungs and subsequent presentation of antigens to the host immune system.
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82
How Important are Host-Specific Genes to Immune responses?
https://www.azolifesciences.com/article/How-Important-are-Host-Specific-Genes-to-Immune-responses.aspx
Tuberculosis (TB) ... Although a strong genetic locus that shows a link between TB susceptibility and genetic polymorphisms is still to be ...
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https://www.azolifesciences.com/article/How-Important-are-Host-Specific-Genes-to-Immune-responses.aspx
Tuberculosis (TB) ... Although a strong genetic locus that shows a link between TB susceptibility and genetic polymorphisms is still to be ...
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83
Innate immunity in bovine tuberculosis - Brunel University
https://www.brunel.ac.uk/research/projects/innate-immunity-in-bovine-tuberculosis
... of bovine tuberculosis infection and how this interaction at the host-pathogen interface contributes to the adaptive immune response ...
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https://www.brunel.ac.uk/research/projects/innate-immunity-in-bovine-tuberculosis
... of bovine tuberculosis infection and how this interaction at the host-pathogen interface contributes to the adaptive immune response ...
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84
Tuberculosis Contenido - MSF Medical Guidelines
https://medicalguidelines.msf.org/sites/default/files/pdf/guideline-1063-es-2022-12-02.pdf
factor that results in a weakened immune system, damaged lungs and the intensity and duration of exposure. Host immune response factors:.
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https://medicalguidelines.msf.org/sites/default/files/pdf/guideline-1063-es-2022-12-02.pdf
factor that results in a weakened immune system, damaged lungs and the intensity and duration of exposure. Host immune response factors:.
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85
Positive T-SPOT blood test brings result of latent tuberculosis
https://www.dailyindependent.com/positive-t-spot-blood-test-brings-result-of-latent-tuberculosis/article_3fcc1048-71db-11ed-b364-0f6f8d6ff945.html
Latent infection means the tuberculosis bacteria are still alive inside you, but kept in check by your immune system.
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https://www.dailyindependent.com/positive-t-spot-blood-test-brings-result-of-latent-tuberculosis/article_3fcc1048-71db-11ed-b364-0f6f8d6ff945.html
Latent infection means the tuberculosis bacteria are still alive inside you, but kept in check by your immune system.
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86
How do vaccines work? | European Commission
https://ec.europa.eu/info/live-work-travel-eu/coronavirus-response/safe-covid-19-vaccines-europeans/how-do-vaccines-work_en
The person's immune system recognises that this unique protein should not be in the body and responds by producing natural defences against infection by COVID- ...
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https://ec.europa.eu/info/live-work-travel-eu/coronavirus-response/safe-covid-19-vaccines-europeans/how-do-vaccines-work_en
The person's immune system recognises that this unique protein should not be in the body and responds by producing natural defences against infection by COVID- ...
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87
HIV/AIDS - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/hiv-aids/symptoms-causes/syc-20373524
By damaging your immune system, HIV interferes with your body's ability to fight infection and disease. Advertisement. Mayo Clinic does not ...
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https://www.mayoclinic.org/diseases-conditions/hiv-aids/symptoms-causes/syc-20373524
By damaging your immune system, HIV interferes with your body's ability to fight infection and disease. Advertisement. Mayo Clinic does not ...
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88
HIV and AIDS: Symptoms, Causes, Treatments, and More
https://www.healthline.com/health/hiv-aids
At that point, the immune system is too weak to successfully respond against other diseases, infections, and conditions. Untreated, life expectancy with end ...
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https://www.healthline.com/health/hiv-aids
At that point, the immune system is too weak to successfully respond against other diseases, infections, and conditions. Untreated, life expectancy with end ...
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89
KEGG PATHWAY Database
https://www.genome.jp/kegg/pathway.html
Organismal Systems 6. Human Diseases ... R - reaction module ... 04672: Intestinal immune network for IgA production; 04062 N: Chemokine signaling pathway.
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https://www.genome.jp/kegg/pathway.html
Organismal Systems 6. Human Diseases ... R - reaction module ... 04672: Intestinal immune network for IgA production; 04062 N: Chemokine signaling pathway.
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90
Definition of prostate-specific antigen - National Cancer Institute
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/prostate-specific-antigen
› cancer-terms › def › prostate-...
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https://www.cancer.gov/publications/dictionaries/cancer-terms/def/prostate-specific-antigen
› cancer-terms › def › prostate-...
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91
HIV and AIDS - Basic facts - UNAIDS
https://www.unaids.org/en/frequently-asked-questions-about-hiv-and-aids
HIV is a retrovirus that infects cells of the human immune system (mainly ... severe bacterial infections and pulmonary tuberculosis) or IV (includes ...
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https://www.unaids.org/en/frequently-asked-questions-about-hiv-and-aids
HIV is a retrovirus that infects cells of the human immune system (mainly ... severe bacterial infections and pulmonary tuberculosis) or IV (includes ...
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92
Risk for Infection Care Plan and Nursing Diagnosis - Nurseslabs
https://nurseslabs.com/risk-for-infection/
The human immune system is crucial for survival in a world full of ... anergic or unable to muster a cellular immune response to pathogens, ...
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https://nurseslabs.com/risk-for-infection/
The human immune system is crucial for survival in a world full of ... anergic or unable to muster a cellular immune response to pathogens, ...
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93
Immunization Reactions - Seattle Children's
https://www.seattlechildrens.org/conditions/a-z/immunization-reactions/
Self Care at Home. Normal immunization reaction (mild redness and swelling, fever) ... Reason: fever speeds up your body's immune system.
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https://www.seattlechildrens.org/conditions/a-z/immunization-reactions/
Self Care at Home. Normal immunization reaction (mild redness and swelling, fever) ... Reason: fever speeds up your body's immune system.
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94
What Happens When Antibiotics Stop Working?
https://www.jnj.com/innovation/what-happens-when-antibiotics-stop-working
Despite an existing tuberculosis (TB) vaccine, drug-resistant ... “If your immune system is compromised, perhaps by a disease like cancer or ...
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https://www.jnj.com/innovation/what-happens-when-antibiotics-stop-working
Despite an existing tuberculosis (TB) vaccine, drug-resistant ... “If your immune system is compromised, perhaps by a disease like cancer or ...
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95
COVID-19 Vaccine Information
https://www.auglaizehealth.org/covid-19-information/vaccine-information
Over time, the immune system's response against COVID-19 can lessen, which may not provide adequate protection against the disease. By getting a booster vaccine ...
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https://www.auglaizehealth.org/covid-19-information/vaccine-information
Over time, the immune system's response against COVID-19 can lessen, which may not provide adequate protection against the disease. By getting a booster vaccine ...
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