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1 The innate immune system in cystic fibrosis lung disease - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC407907/
Despite the alterations of the innate immune system, the adaptive immune system seems to be intact. Most patients develop antibodies to antigens of P.
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2 Why Are Some Germs Particularly Dangerous for People With ...
https://www.cff.org/managing-cf/why-are-some-germs-particularly-dangerous-people-cf
› managing-cf › why-are-some-ger...
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3 Current Concepts and Controversies in Innate Immunity of ...
https://www.karger.com/Article/Fulltext/446840
Cystic fibrosis (CF) lung disease is characterized by chronic infection and inflammation. The inflammatory response in CF is dominated by the ...
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4 Immune Responses in Cystic Fibrosis | Are They Intrinsically ...
https://www.atsjournals.org/doi/full/10.1165/rcmb.2011-0399rt
Patients with CF have a tendency toward allergic reactions, asthma, dermatitis, and hyperinflammatory immune responses. Although lymphocytes ...
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5 Enhancing Cystic Fibrosis Immune Regulation - Frontiers
https://www.frontiersin.org/articles/10.3389/fphar.2021.573065/full
In cystic fibrosis (CF), sustained infection and exuberant inflammation results in debilitating and often fatal lung disease.
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6 Impaired innate immune cells in cystic fibrosis: Is it really a ...
https://www.cysticfibrosisjournal.com/article/s1569-1993(17)30769-5/fulltext
Because of the interplay between host defense and the airway inflammatory response, investigators have begun to focus on other cells besides the ...
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7 Innate immunity in cystic fibrosis lung disease - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S1569199312001336
Chronic lung disease determines the morbidity and mortality of cystic fibrosis (CF) patients. The pulmonary immune response in CF is characterized by an ...
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8 Cystic Fibrosis - CDC
https://www.cdc.gov/genomics/disease/cystic_fibrosis.htm
Cystic Fibrosis · blocks airways and leads to lung damage; · traps germs and makes infections more likely; and · prevents proteins needed for digestion from ...
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9 Neutrophil extracellular traps and the dysfunctional innate ...
https://journal-inflammation.biomedcentral.com/articles/10.1186/s12950-017-0176-1
Cystic Fibrosis (CF) is a devastating genetic disease characterised primarily by unrelenting lung inflammation and infection resulting in ...
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10 Cystic fibrosis: Additional immune dysfunction discovered
https://www.sciencedaily.com/releases/2014/09/140904084508.htm
Cystic fibrosis (CF) is a frequent genetic disease affecting the lung and the gastrointestinal tract. Scientists have now shown that many of ...
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11 Can we Train the Immune System of Patients With Cystic ...
https://www.archbronconeumol.org/en-can-we-train-immune-system-articulo-S0300289620303975
The importance of exercise in cystic fibrosis (CF) is well known since regular training is able to reduce lung function decline and to improve exercise ...
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12 New Cystic Fibrosis Research Sheds Light on Cause of ...
https://cysticfibrosisnewstoday.com/news/new-cystic-fibrosis-research-sheds-light-on-cause-of-impaired-immune-response-in-adult-patients/
While cells from the immune system play a role in the disease, scientists from the Helmholtz Zentrum München hypothesized that CF patients might ...
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13 Immunomodulation in Cystic Fibrosis - MDPI
https://www.mdpi.com/1422-0067/21/9/3331
Cystic fibrosis (CF) lung disease is characterized by unconventional mechanisms of inflammation, implicating a chronic immune response dominated by innate ...
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14 Incapacitating the immune system in cystic fibrosis - Nature
https://www.nature.com/articles/nm1207-1417
In cystic fibrosis, the immune system bombards bacteria invading the airways, but the effort does not clear the pathogen. Now, Hartl et al.
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15 Immunity, nutrition, cystic fibrosis and COVID-19
https://www.cfnz.org.nz/news-and-events/latest-news/immunity-nutrition-cystic-fibrosis-and-covid-19/
However, people with CF are at increased risk of lung infections post viral infections due to interactions between their immune systems and ...
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16 The Basics of CF | The Cystic Fibrosis Center at Stanford
https://med.stanford.edu/cfcenter/education/english/BasicsOfCF.html
› cfcenter › education › english
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17 Cystic Fibrosis - NORD (National Organization for Rare ...
https://rarediseases.org/rare-diseases/cystic-fibrosis/
The immune system of individuals with cystic fibrosis responds to an infection by sending white blood cells to attack the infection.
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18 Atypical Activation of the Unfolded Protein Response in Cystic ...
https://www.jimmunol.org/content/189/11/5467
Inflammatory lung disease is the major cause of morbidity and mortality in cystic fibrosis (CF); understanding what produces dysregulated innate immune ...
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19 Alterations in innate immune responses of patients with ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0267986
Cystic fibrosis (CF) is characterized by an excessive inflammatory response and the failure to efficiently resolve lung infections, ...
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20 Immune-System Cells May Promote Chronic Infections in ...
https://www.nationaljewish.org/about/news/press-releases/2005/cf_biofilm
Cells sent to fight infections in the lungs of cystic fibrosis patients actually enhance the development of permanent bacterial infections, ...
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21 Cystic Fibrosis and the Innate Immune System: Therapeutic ...
https://www.eurekaselect.com/article/32613
The hallmarks of CF lung disease are respiratory infection by opportunistic pathogens and a deranged inflammatory response. However, clinical and experimental ...
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22 Dysregulated signalling pathways in innate immune cells with ...
https://link.springer.com/article/10.1007/s00018-020-03540-9
Innate immune cells are generally affected by CFTR mutations in patients with CF, leading to dysregulation of several cellular signalling ...
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23 Cystic fibrosis and innate immunity: how chloride channel ...
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1462-5822.2008.01271.x
Thus, CFTR itself can be regarded as a substantial part of the innate immune system and mutant or missing CFTR has been linked to the initiation ...
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24 Airway inflammation in cystic fibrosis - Thorax BMJ
https://thorax.bmj.com/content/68/12/1157
Inflammation develops in CF airways early in life in response to extracellular infectious stimuli and possibly due to immune dysregulation which includes ...
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25 Cystic fibrosis - Diagnosis and treatment - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/cystic-fibrosis/diagnosis-treatment/drc-20353706
To diagnose cystic fibrosis, doctors typically do a physical exam, ... CF doesn't affect the immune system, but children with CF are more ...
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26 How Cystic Fibrosis Affects Breathing and the Lungs
https://wa.kaiserpermanente.org/kbase/topic.jhtml?docId=hw184872
Cystic fibrosis causes the mucus that coats the breathing tubes to become so thick and sticky that the cilia are unable to sweep the germs and other particles ...
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27 Cystic fibrosis: Symptoms, treatments, causes, and diagnosis
https://www.medicalnewstoday.com/articles/147960
Cystic fibrosis (CF) is a genetic disease that affects the lungs, digestive system, and other organs. It develops when the protein that produces mucus does ...
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28 Lung immunoglobulin A immunity dysregulation in cystic fibrosis
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(20)30350-9/fulltext
In cystic fibrosis (CF), recurrent infections suggest impaired mucosal immunity but whether production of secretory immunoglobulin A (S-IgA) ...
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29 Consequences of cystic fibrosis transmembrane ... - OAText
https://oatext.com/Consequences-of-cystic-fibrosis-transmembrane-regulator-mutations-on-inflammatory-cells.php
Cystic fibrosis patients are susceptible to infections of opportunistic extracellular or intracellular pathogens, the appropriate immune response is different ...
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30 Microbial infection in cystic fibrosis
https://www.immunology.org/public-information/bitesized-immunology/pathogens-disease/microbial-infection-cystic-fibrosis
The defective gene is the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR protein is present on epithelial cells throughout the body. It is ...
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31 Identification of molecular signatures of cystic fibrosis disease ...
https://journals.physiology.org/doi/full/10.1152/physiolgenomics.00109.2018
Cystic fibrosis (CF) is an inherited multisystem disease characterized by pancreatic insufficiency and progressive deterioration of lung function. CF is ...
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32 Cystic Fibrosis Symptoms & Treatment | Children's Pittsburgh
https://www.chp.edu/our-services/transplant/liver/education/liver-disease-states/cystic-fibrosis
Cystic Fibrosis Treatment · Childhood immunizations. Cystic fibrosis doesn't affect the immune system itself, but children with cystic fibrosis are more likely ...
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33 To Everyone's Surprise, COVID-19 Spared My Lungs
https://cystic-fibrosis.com/living/covid-19-experience
After a lifetime of being beaten down by the slightest of colds due to having cystic fibrosis (CF), I knew that my immune system was now the strongest it ...
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34 Cystic fibrosis: Genetics and pathogenesis - UpToDate
https://www.uptodate.com/contents/cystic-fibrosis-genetics-and-pathogenesis
Cystic fibrosis (CF) is a multisystem disease affecting the lungs, digestive system, sweat glands, and reproductive tract.
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35 Lack of an exaggerated inflammatory response on virus ...
https://erj.ersjournals.com/content/39/2/297
Respiratory virus infections play an important role in cystic fibrosis (CF) exacerbations, but underlying pathophysiological mechanisms are poorly understood.
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36 Neutrophil dysfunction in the pathogenesis of cystic fibrosis
https://ashpublications.org/blood/article/139/17/2622/484179/Neutrophil-dysfunction-in-the-pathogenesis-of
Failure to terminate the inflammatory response and its causes can fuel exuberant inflammation characteristic of many human diseases, including ...
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37 How cystic fibrosis affects the lungs
https://www.cysticfibrosis.org.uk/what-is-cystic-fibrosis/how-does-cystic-fibrosis-affect-the-body/cystic-fibrosis-complications/lungs
› what-is-cystic-fibrosis
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38 Cystic Fibrosis - Medscape Reference
https://emedicine.medscape.com/article/1001602-overview
Cystic fibrosis (CF) is a disease of exocrine gland function that involves multiple organ systems but chiefly results in chronic respiratory ...
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39 Vitamin D for the Immune System in Cystic Fibrosis (DISC): a ...
https://academic.oup.com/ajcn/article/109/3/544/5359447
Patients with cystic fibrosis (CF) have increased risk of vitamin D deficiency owing to fat malabsorption and other factors. Vitamin D ...
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40 Cystic fibrosis faithfully modeled in a human Lung Airway Chip
https://www.eurekalert.org/news-releases/935581
(BOSTON) — The inherited progressive disorder cystic fibrosis (CF) causes severe damage to the lungs, and other tissues in the body by affecting ...
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41 Role of the cystic fibrosis transmembrane ... - PNAS
https://www.pnas.org/doi/10.1073/pnas.97.16.8822
Among the more puzzling failures of the innate immune system are the ones associated with defects in the gene encoding the cystic fibrosis (CF) ...
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42 A Review of The Role of The Microbiome on Immune ...
http://immunoreg.shahed.ac.ir/article_3016.html
CF is an extremely complex disease that results from a gene mutation. Lack of expression of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) has late ...
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43 Cystic Fibrosis: Causes, Diagnosis, and Treatment - Healthline
https://www.healthline.com/health/cystic-fibrosis
Cystic fibrosis (CF) is a serious genetic condition that causes severe damage to the respiratory and digestive systems. This damage often results from a ...
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44 Cystic Fibrosis | HMRI
https://hmri.org.au/research/viruses-infections-immunity-vaccines-asthma/cystic-fibrosis
A baby is born with cystic fibrosis every four days (Source – Better Health Channel). It primarily affects the respiratory system with recurrent infections ...
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45 Causes - - - Bronchiectasis - NHS
https://www.nhs.uk/conditions/bronchiectasis/causes/
Cystic fibrosis is a genetic disorder, where the lungs become clogged up with mucus. The mucus then provides an ideal environment for a bacterial infection to ...
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46 Cystic Fibrosis (CF): Causes, Symptoms, Diagnosis & Treatment
https://my.clevelandclinic.org/health/diseases/9358-cystic-fibrosis
Cystic fibrosis (CF) is a genetic (inherited) disease that causes sticky, thick mucus to build up in organs, including the lungs and the ...
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47 Lung Disease: Pneumonia, Cystic Fibrosis, & Pulmonary ...
https://www.houstonmethodist.org/pulmonology/lung-disease/
› pulmonology › lu...
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48 Cystic Fibrosis | Johns Hopkins Medicine
https://www.hopkinsmedicine.org/health/conditions-and-diseases/cystic-fibrosis
Cystic fibrosis (CF) is an inherited life-threatening disease that affects many organs. It causes changes in the electrolyte transport system causing cells to ...
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49 Succinate links mitochondria to deadly bacteria in cystic fibrosis
https://atm.amegroups.com/article/view/33629/html
Cystic fibrosis (CF) is a life shortening–autosomal recessive disease caused by ... The fact that succinate-fed bacteria suppress the host immune system, ...
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50 Model Systems to Study the Chronic, Polymicrobial Infections ...
https://journals.asm.org/doi/10.1128/mBio.01763-21
... sponsored by the Dartmouth Cystic Fibrosis Center (DartCF), ... the host (including the immune response), or the host-microbe(s) ...
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51 COVID-19 Antibody Responses in Cystic Fibrosis (CAR-CF)
https://clinicaltrials.gov/ct2/show/NCT05217784
... [ Time Frame: anticipated 5-10 year ] Storage of samples for future analysis on the impact of COVID-19 immune response in people with cystic fibrosis.
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52 CYSTIC FIBROSIS INFECTION PREVENTION AND ...
https://www.cysticfibrosis.ca/uploads/FAQ_Infection%20Prevention%20and%20Control%20Guidelines_FINAL.pdf
rid of, due to their compromised immune system. Lung infection flare-ups are a leading cause of illness and death in people with CF.
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53 A bacterium that tricks the immune system into nurturing it
https://www.economist.com/science-and-technology/a-bacterium-that-tricks-the-immune-system-into-nurturing-it/21809237
That finding alone is interesting, because it helps explain why cystic-fibrosis patients with bacterial infections often develop copious ...
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54 COVID-19 may infect people with cystic fibrosis differently
https://www.drugdiscoverynews.com/does-covid-19-infect-people-with-cystic-fibrosis-differently-15349
Cystic fibrosis (CF), a condition marked by the overproduction of thick and sticky mucus in the lungs, has a more complicated relationship.
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55 Snapshot of the cystic fibrosis (CF) immune system and ...
https://www.researchgate.net/figure/Snapshot-of-the-cystic-fibrosis-CF-immune-system-and-processes-affected-by-mutant_fig1_221689681
› figure › Snapshot-of-the-c...
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56 Role of Neutrophils in Cystic Fibrosis Lung Disease
https://www.intechopen.com/chapters/54594
The hallmark of the CF lung disease is a neutrophil‐dominated inflammatory response; however, the link between CFTR mutations and the complex ...
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57 Drugs to suppress the immune system after lung ... - Cochrane
https://www.cochrane.org/CD009421/CF_drugs-suppress-immune-system-after-lung-transplantation-people-cystic-fibrosis
Lung transplantation is an available and realistic treatment option for people with cystic fibrosis whose lungs are severely damaged. However, ...
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58 Cystic Fibrosis Most Common Infections and Prevention
https://www.cvsspecialty.com/resource-center/cystic-fibrosis/cystic-fibrosis-and-preventing-infections.html
› resource-center › cystic...
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59 Treating and Managing Cystic Fibrosis
https://www.lung.org/lung-health-diseases/lung-disease-lookup/cystic-fibrosis/treating-and-managing
Your physician should also be alerted immediately to any complications so that they can provide supplemental medication to help the immune system fight off ...
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60 Cystic Fibrosis - Learn Genetics Utah
https://learn.genetics.utah.edu/content/genetics/cysticfibrosis
For example, there are other genes that affect how the lungs or the pancreas work. Many genes influence how well the immune system responds to infection. Still ...
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61 Cystic Fibrosis - Symptoms, Causes & Natural treatments
https://advancedfunctionalmedicine.com.au/cystic-fibrosis-symptoms-causes-natural-treatment/
Cystic fibrosis is a multi-system autosomal-recessive genetic disorder that affects the lungs, pancreas, liver and intestine.
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62 The innate immune system in cystic fibrosis lung disease - Wikidata
https://www.wikidata.org/wiki/Q40848578
The innate immune system in cystic fibrosis lung disease. scientific article. In more languages. Spanish. No label defined. artículo científico publicado en ...
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63 Pulmonology and Cystic Fibrosis Treatment
https://www.rwjbh.org/rwjbarnabas-health-medical-group/our-specialties/adult-pulmonology-cystic-fibrosis/
Nutrition counseling to create a diet that improves lung function, boosts the immune system, and lowers mucus levels. Pulmonary rehab to learn new breathing ...
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64 Abnormalities in the Pulmonary Innate Immune System in ...
http://citeseerx.ist.psu.edu/viewdoc/download;jsessionid=D43163E4DCFD469B9FF83CB92F2F508F?doi=10.1.1.328.7318&rep=rep1&type=pdf
Pulmonary infection is the dominant clinical feature of cystic fibrosis. (CF), but the basis for this susceptibility remains incompletely un- derstood.
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65 Cystic fibrosis drug trialled to fight inflammation caused by ...
https://www.crick.ac.uk/news/2020-07-10_cystic-fibrosis-drug-trialled-to-fight-inflammation-caused-by-covid-19
Researchers believe the immune system in COVID-19 patients is over-active and an abundance of NETs could be causing excess inflammation ...
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66 Cystic fibrosis transmembrane conductance regulator (CFTR ...
https://www.oncotarget.com/article/27037/text/
In the CD intestine, the ingestion of gluten proteins including gliadin results into an adaptive immune response against gliadin-derived ...
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67 Cystic Fibrosis Impact on Cellular Function - Carroll Collected
https://collected.jcu.edu/cgi/viewcontent.cgi?article=1050&context=honorspapers
Since the CFTR protein alters function of immune cells, an abnormal immune response could cause CF patients to become more immunocompromised (29). Neutrophils ...
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68 Nutrition and immunity in cystic fibrosis
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/520151B94BFD9B6E029874470D18BE01/S0029665177000159a.pdf/nutrition-and-immunity-in-cystic-fibrosis.pdf
The precise defect in cystic fibrosis is still unknown despite vast ... child's immune system. ... suggested that the IgA system may be defective in CF.
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69 Cystic fibrosis - Wikipedia
https://en.wikipedia.org/wiki/Cystic_fibrosis
Cystic fibrosis (CF) is a rare genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine.
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70 Innate immunity in cystic fibrosis lung disease - Air University
https://aul.primo.exlibrisgroup.com/discovery/fulldisplay?docid=cdi_openaire_primary_oai_dnet_dedup_wf_001_ef82c4a2bec8b9d0f9f649689a931d64&context=PC&vid=01AUL_INST:AUL&lang=en&search_scope=MyInst_and_CI&adaptor=Primo%20Central&query=creator%2Cexact%2C%20Zhou-Suckow%2C%20Zhe%20&facet=citing%2Cexact%2Ccdi_FETCH-LOGICAL-c544t-c6bdf8aa30fbafea589b3b17305864a8956301bb46ac64101c06fed8e00a00443&offset=40
Abstract Chronic lung disease determines the morbidity and mortality of cystic fibrosis (CF) patients. The pulmonary immune response in CF is characterized ...
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71 Immunology | European Cystic Fibrosis Society (ECFS)
https://www.ecfs.eu/research-article-themes/immunology
Immune response after COVID-19 vaccination in cystic fibrosis patients · Reduced levels of nitric oxide in cystic fibrosis airways may be caused by interleukin-1 ...
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72 Cystic Fibrosis in the Intestine and the Influence on Digestion
https://www.immunologyresearchjournal.com/articles/cystic-fibrosis-in-the-intestine-and-the-influence-on-digestion.html
The immune response may also be influenced by CFTR through its expression in lymphocytes and natural killer (NK) cells55,56. Moreover, ...
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73 Cystic fibrosis and preventing infections - Coram
https://www.coramhc.com/patients/cystic-fibrosis-and-preventing-infections
That's because CF leads to thick, sticky mucus buildup in your airways. The mucus traps germs and makes it easier for them to grow. As your body's immune system ...
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74 Immune Cells Play Role in Cystic Fibrosis Lung Damage
https://www.disabled-world.com/health/respiratory/cystic-fibrosis/immune-cells-role.php
Immune cells play surprising role in cystic fibrosis lung damage, Stanford/Packard study shows. Immune cells once thought to be innocent ...
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75 Are patients with lung cystic fibrosis at increased risk of severe ...
https://www.mp.pl/paim/issue/article/15630
Furthermore, patients with CF are at increased risk of severe infection with other viruses affecting the respiratory system. Influenza viruses, ...
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76 Cystic Fibrosis and Its Management Through Established and ...
https://www.annualreviews.org/doi/10.1146/annurev-genom-090314-050024
In addition, recent studies have reported CFTR expression and defects in other organs and tissues, including the central nervous system, leukocytes, smooth ...
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77 Cystic Fibrosis and Nutrition (for Parents) - Nemours KidsHealth
https://kidshealth.org/en/parents/cf-nutrition.html
Cystic fibrosis (CF) is a genetic disorder that affects the body's epithelial cells. These cells are found in many places, including the sweat glands, ...
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78 Different CFTR modulator combinations downregulate ... - eLife
https://elifesciences.org/articles/54556
Cystic fibrosis (CF) is characterised by repeated pulmonary infections and disordered innate immune-driven inflammation. · The NLRP3-inflammasome ...
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79 Cystic fibrosis | Lima Memorial Health System
https://www.limamemorial.org/health-library/Complementary%20and%20Alternative%20Medicine/33/000045
Cystic fibrosis (CF) is a chronic, progressive, and frequently fatal genetic disease of the glands that produce or secrete sweat and mucus.
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80 Cystic Fibrosis Lung Disease: An Overview - Respiratory Care
https://rc.rcjournal.com/content/65/2/233
Cystic fibrosis (CF), a single-gene disease with autosomal recessive inheritance, is caused by a mutation (chemical change) in the CF gene aptly ...
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81 Connective tissue and autoimmune diseases
https://www.blf.org.uk/support-for-you/pulmonary-fibrosis/autoimmune
What is pulmonary fibrosis caused by connective tissue and autoimmune diseases? ... For reasons we don't fully understand, sometimes the immune system turns ...
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82 Definition of cystic fibrosis - NCI Dictionary of Cancer Terms
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/cystic-fibrosis
› cancer-terms › def › cystic-fi...
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83 Why is cystic fibrosis so hard to treat? - Chemistry World
https://www.chemistryworld.com/features/why-is-cystic-fibrosis-so-hard-to-treat/4012206.article
Pseudomonas is an opportunistic pathogen that only infects people with weakened immune systems. There are multiple mechanistic pathways ...
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84 Lung Transplantation and Extracorporeal Photopheresis as ...
https://www.jhltonline.org/article/S1053-2498(22)00311-4/fulltext
Lung Transplantation and Extracorporeal Photopheresis as Induction Therapy in Cystic Fibrosis Patients: Immune System Profile Changes.
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85 Infection and Immunity | Cystic Fibrosis Research Center
https://www.cfrc.pitt.edu/cores/infection-and-immunity
Respiratory failure due to acute and chronic infections and aberrant inflammatory responses, is the primary cause of death in patients with Cystic Fibrosis ...
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86 The immunology and infection of the cystic fibrosis lung.
https://researchrepository.wvu.edu/etd/8787/
... between the CF host immune response and the pathophysiology of cystic fibrosis before and after bacterial infection with Pseudomonas aeruginosa.
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87 What to Know About Cystic Fibrosis and COVID-19
https://www.verywellhealth.com/cystic-fibrosis-and-coronavirus-covid-19-5118063
1 It causes sticky mucus to build up in the lungs and digestive system. As CF affects the lungs, you may be concerned about what it may mean for ...
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88 Cytokine IFN-γ Helps Clear Lethal Bacteria In Cystic Fibrosis
https://rtmagazine.com/disorders-diseases/chronic-pulmonary-disorders/cystic-fibrosis/cytokine-helps-clear-lethal-bacteria-in-cystic-fibrosis/
Produced by the IFNG gene in humans, IFN-? is a cytokine active in the immune system. Studies have suggested that the molecule stimulates autophagy, a natural ...
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89 Airway inflammation in cystic fibrosis
https://www.ers-education.org/lr/show-media/?id=305941
Cystic fibrosis (CF) is a multisystem disorder with significantly shortened life expectancy. The major cause of mortality and morbidity is lung disease.
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90 New drug shows potential to treat cystic fibrosis patients - RCSI
https://www.rcsi.com/impact/details/2022/03/new-drug-shows-potential-to-treat-cystic-fibrosis-patients
› impact › details › 2022/03 › ne...
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91 Cystic fibrosis: deciphering the complexity - CORE
https://core.ac.uk/download/pdf/82492570.pdf
pathogens without triggering a substantial innate immune response [8]. In the lungs of CF patients, this film is thinner than under normal conditions and ...
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92 UM Research Reveals How Bacteria Defeat Drugs That Fight ...
https://www.umt.edu/news/2021/02/022521bact.php
Cystic fibrosis is a life-threatening disease that causes persistent lung infections and limits a person's ability to breathe over time. A ...
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93 Emerging gene therapies for cystic fibrosis
https://www.tandfonline.com/doi/abs/10.1080/17476348.2019.1634547?journalCode=ierx20
Introduction: Cystic fibrosis (CF) remains a life-threatening genetic disease, ... approaches to subvert the humoral immune system and increase gene ...
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94 Immune Dysfunction in Cystic Fibrosis | ZSR Library
https://wakespace.lib.wfu.edu/handle/10339/90699
abstract: Cystic Fibrosis (CF) is one of the most widespread ... infection and production of a disproportionate inflammatory response to microbial stimuli.
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95 Chest infection | NHS inform
https://www.nhsinform.scot/illnesses-and-conditions/infections-and-poisoning/chest-infection
... cystic fibrosis or chronic obstructive pulmonary disease (COPD); people with a weakened immune system – this could be due to a recent ...
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96 Repeat Dosing of AAV2.5T to Ferret Lungs Elicits an Antibody ...
https://www.cell.com/molecular-therapy-family/methods/fulltext/S2329-0501(20)30193-5
Thus, age-dependent immune system maturation and isotype switching may ... Cystic fibrosis (CF) is an autosomal recessive disease caused by ...
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