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Google Keyword Rankings for : telomerase shortening aging
1
Telomere shortening and ageing - PubMed
https://pubmed.ncbi.nlm.nih.gov/17943234/
Telomere shortening can act as a tumor suppressor. However, as a downside, there is growing evidence indicating that telomere shortening also limits stem cell ...
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https://pubmed.ncbi.nlm.nih.gov/17943234/
Telomere shortening can act as a tumor suppressor. However, as a downside, there is growing evidence indicating that telomere shortening also limits stem cell ...
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2
Telomere Length as a Marker of Biological Age - Frontiers
https://www.frontiersin.org/articles/10.3389/fgene.2020.630186/full
Telomere shortening is a well-known hallmark of both cellular senescence and organismal aging. An accelerated rate of telomere attrition is ...
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https://www.frontiersin.org/articles/10.3389/fgene.2020.630186/full
Telomere shortening is a well-known hallmark of both cellular senescence and organismal aging. An accelerated rate of telomere attrition is ...
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3
Are Telomeres the Key to Aging and Cancer
https://learn.genetics.utah.edu/content/basics/telomeres/
Yet, each time a cell divides, the telomeres get shorter. When they get too short, the cell can no longer divide; it becomes inactive or "senescent" or it dies.
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https://learn.genetics.utah.edu/content/basics/telomeres/
Yet, each time a cell divides, the telomeres get shorter. When they get too short, the cell can no longer divide; it becomes inactive or "senescent" or it dies.
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4
Video: How telomere shortening affects aging - RepeatDx
https://repeatdx.com/video-telomere-shortening-aging/
It is natural that telomeres shorten as we grow and age. However, some people have abnormally short telomeres throughout their life. Some can ...
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https://repeatdx.com/video-telomere-shortening-aging/
It is natural that telomeres shorten as we grow and age. However, some people have abnormally short telomeres throughout their life. Some can ...
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5
Telomere dysfunction in ageing and age-related diseases
https://www.nature.com/articles/s41556-022-00842-x
Ageing organisms accumulate senescent cells that are thought to contribute to body dysfunction. Telomere shortening and damage are ...
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https://www.nature.com/articles/s41556-022-00842-x
Ageing organisms accumulate senescent cells that are thought to contribute to body dysfunction. Telomere shortening and damage are ...
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6
Telomere shortening rate predicts species life span - PNAS
https://www.pnas.org/doi/10.1073/pnas.1902452116
Telomere shortening to a critical length can trigger aging and shorter life spans in mice and humans by a mechanism that involves induction of a persistent ...
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https://www.pnas.org/doi/10.1073/pnas.1902452116
Telomere shortening to a critical length can trigger aging and shorter life spans in mice and humans by a mechanism that involves induction of a persistent ...
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7
You may have more control over aging than you think, say ...
https://www.statnews.com/2017/01/03/aging-control-telomere-effect/
The main message of “The Telomere Effect,” being published Tuesday, is that you have more control over your own aging than you may imagine. You ...
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https://www.statnews.com/2017/01/03/aging-control-telomere-effect/
The main message of “The Telomere Effect,” being published Tuesday, is that you have more control over your own aging than you may imagine. You ...
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8
Telomere Shortening, Aging, and Cancer - News Medical
https://www.news-medical.net/life-sciences/Telomere-Shortening-Aging-and-Cancer.aspx
Telomere Shortening and Aging ... Telomeres affect how our cells age. Once they lose a certain number of bases and become too short, the cell can ...
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https://www.news-medical.net/life-sciences/Telomere-Shortening-Aging-and-Cancer.aspx
Telomere Shortening and Aging ... Telomeres affect how our cells age. Once they lose a certain number of bases and become too short, the cell can ...
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9
Telomeres: The Role of Shortening in Cancer and Aging, How ...
https://www.healthline.com/health/telomeres
Telomeres help protect your chromosomes from damage. In the process, your telomeres shorten, which is associated with aging and disease development. But recent ...
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https://www.healthline.com/health/telomeres
Telomeres help protect your chromosomes from damage. In the process, your telomeres shorten, which is associated with aging and disease development. But recent ...
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10
Telomere Shortening - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/telomere-shortening
Telomere shortening is one of the more widely accepted theories of aging within the scientific community. However, age-induced telomere attrition seems to ...
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https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/telomere-shortening
Telomere shortening is one of the more widely accepted theories of aging within the scientific community. However, age-induced telomere attrition seems to ...
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11
Telomeres and Aging | Physiological Reviews
https://journals.physiology.org/doi/10.1152/physrev.00026.2007
Telomeres play a central role in cell fate and aging by adjusting the cellular response to stress and growth stimulation on the basis of previous cell ...
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https://journals.physiology.org/doi/10.1152/physrev.00026.2007
Telomeres play a central role in cell fate and aging by adjusting the cellular response to stress and growth stimulation on the basis of previous cell ...
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12
Markers of cellular senescence. Telomere shortening as a ...
https://www.aging-us.com/article/100871/text
Telomere theory, a major aging theory, is based on this telomeres shortening mechanism [6, 7, 9] and indicates telomeres as a promising marker of cellular ...
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https://www.aging-us.com/article/100871/text
Telomere theory, a major aging theory, is based on this telomeres shortening mechanism [6, 7, 9] and indicates telomeres as a promising marker of cellular ...
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13
Telomere extension turns back aging clock in cultured human ...
https://med.stanford.edu/news/all-news/2015/01/telomere-extension-turns-back-aging-clock-in-cultured-cells.html
In young humans, telomeres are about 8,000-10,000 nucleotides long. They shorten with each cell division, however, and when they reach a ...
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https://med.stanford.edu/news/all-news/2015/01/telomere-extension-turns-back-aging-clock-in-cultured-cells.html
In young humans, telomeres are about 8,000-10,000 nucleotides long. They shorten with each cell division, however, and when they reach a ...
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14
Telomere Shortening With Aging in Human Liver
https://academic.oup.com/biomedgerontology/article/55/11/B533/563335
Progressive telomere shortening with aging was studied in the normal liver tissue of 94 human subjects aged between 0 and 101 years old to determine the ...
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https://academic.oup.com/biomedgerontology/article/55/11/B533/563335
Progressive telomere shortening with aging was studied in the normal liver tissue of 94 human subjects aged between 0 and 101 years old to determine the ...
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15
The Telomere Theory of Aging - Verywell Health
https://www.verywellhealth.com/telomere-shortening-the-secret-to-aging-2224346
In population-level studies, researchers have found that older people have shorter telomeres.4 Eventually, the cells with shorter telomeres can ...
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https://www.verywellhealth.com/telomere-shortening-the-secret-to-aging-2224346
In population-level studies, researchers have found that older people have shorter telomeres.4 Eventually, the cells with shorter telomeres can ...
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16
Correlation Between Telomere Length and Biomarkers of ...
https://www.liebertpub.com/doi/10.1089/rej.2021.0045
The shortening of telomeres has been shown related to the aging of the organism. It has been shown that telomere shortens with age and in ...
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https://www.liebertpub.com/doi/10.1089/rej.2021.0045
The shortening of telomeres has been shown related to the aging of the organism. It has been shown that telomere shortens with age and in ...
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17
Lifestyle effects on telomeric shortening as a factor associated ...
https://content.iospress.com/articles/nutrition-and-healthy-aging/nha200096
Telomere shortening and its role in aging has gained recognition since the 1990s [15]. Nonetheless, the increase in unhealthy lifestyles and ...
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https://content.iospress.com/articles/nutrition-and-healthy-aging/nha200096
Telomere shortening and its role in aging has gained recognition since the 1990s [15]. Nonetheless, the increase in unhealthy lifestyles and ...
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18
Telomerase deficiency reflects age-associated changes in ...
https://immunityageing.biomedcentral.com/articles/10.1186/s12979-022-00273-0
Our data suggest that telomere shortening could play a key role in the aging of T cell immunity, with clinical implications for immune diseases ...
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https://immunityageing.biomedcentral.com/articles/10.1186/s12979-022-00273-0
Our data suggest that telomere shortening could play a key role in the aging of T cell immunity, with clinical implications for immune diseases ...
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19
Potential of Naturally Derived Compounds in Telomerase and ...
https://www.mdpi.com/1422-0067/22/12/6381
5. Roles of Telomeres in Skin Aging. The primary indicators of aging are telomere attrition, epigenetic and mitochondrial dysfunction, and general DNA damage.
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https://www.mdpi.com/1422-0067/22/12/6381
5. Roles of Telomeres in Skin Aging. The primary indicators of aging are telomere attrition, epigenetic and mitochondrial dysfunction, and general DNA damage.
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20
Role of Telomeres and Telomerase in Aging and Cancer
https://aacrjournals.org/cancerdiscovery/article/6/6/584/5789/Role-of-Telomeres-and-Telomerase-in-Aging-and
All somatic normal human cells display progressive telomere shortening with increased cell divisions. In the absence of a mechanism to maintain telomeres, cells ...
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https://aacrjournals.org/cancerdiscovery/article/6/6/584/5789/Role-of-Telomeres-and-Telomerase-in-Aging-and
All somatic normal human cells display progressive telomere shortening with increased cell divisions. In the absence of a mechanism to maintain telomeres, cells ...
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21
Telomerase and telomeres in aging theory and chronographic ...
https://www.spandidos-publications.com/10.3892/mmr.2020.11274
Telomere shortening is most pronounced during bone marrow resection, as it has been observed that there is an inverse correlation between the ...
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https://www.spandidos-publications.com/10.3892/mmr.2020.11274
Telomere shortening is most pronounced during bone marrow resection, as it has been observed that there is an inverse correlation between the ...
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22
Telomere Length and Cellular Aging - NMN
https://www.nmn.com/news/telomere-length-aging
The age-related telomere shortening phenomenon is highly complex, and biological mechanisms underlying this process are not yet definitively ...
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https://www.nmn.com/news/telomere-length-aging
The age-related telomere shortening phenomenon is highly complex, and biological mechanisms underlying this process are not yet definitively ...
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23
Telomerase and the Aging Heart - Science
https://www.science.org/doi/10.1126/sageke.2003.19.pe11
If successive shortening of telomeres leads to cellular senescence, then the corollary of this hypothesis of cell aging would suggest that maintaining telomere ...
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https://www.science.org/doi/10.1126/sageke.2003.19.pe11
If successive shortening of telomeres leads to cellular senescence, then the corollary of this hypothesis of cell aging would suggest that maintaining telomere ...
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24
Why Do We Age? | Telomere Shortening - NOVOS Labs
https://novoslabs.com/causes-of-aging-telomere-shortening/
Given that during aging telomeres become shorter after each cell division, it was assumed that telomere length could tell you something about your remaining ...
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https://novoslabs.com/causes-of-aging-telomere-shortening/
Given that during aging telomeres become shorter after each cell division, it was assumed that telomere length could tell you something about your remaining ...
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25
5 Strategies to Slow Telomere Shortening - Inside Tracker blog
https://blog.insidetracker.com/strategies-slow-telomere-reduction
Mounting evidence indicates that telomere length declines with age, and their rate of shortening may be indicative of how fast someone ages.
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https://blog.insidetracker.com/strategies-slow-telomere-reduction
Mounting evidence indicates that telomere length declines with age, and their rate of shortening may be indicative of how fast someone ages.
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26
Telomere shortening protects against cancer
https://www.rockefeller.edu/news/29625-telomere-shortening-protects-cancer/
Human telomeres (green) at the ends of chromosomes (blue). As time goes by, the tips of your chromosomes—called telomeres—become shorter. This ...
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https://www.rockefeller.edu/news/29625-telomere-shortening-protects-cancer/
Human telomeres (green) at the ends of chromosomes (blue). As time goes by, the tips of your chromosomes—called telomeres—become shorter. This ...
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27
Lifestyle Changes May Lengthen Telomeres, A Measure of ...
https://www.ucsf.edu/news/2013/09/108886/lifestyle-changes-may-lengthen-telomeres-measure-cell-aging
In recent years, shorter telomeres have become associated with a broad range of aging-related diseases, including many forms of cancer, ...
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https://www.ucsf.edu/news/2013/09/108886/lifestyle-changes-may-lengthen-telomeres-measure-cell-aging
In recent years, shorter telomeres have become associated with a broad range of aging-related diseases, including many forms of cancer, ...
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28
Why We Age: Telomere Attrition | Lifespan.io
https://www.lifespan.io/topic/telomere-attrition/
The Hallmarks of Aging [1] describes telomere attrition (or telomere shortening), which is the gradual loss of the protective caps of our ...
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https://www.lifespan.io/topic/telomere-attrition/
The Hallmarks of Aging [1] describes telomere attrition (or telomere shortening), which is the gradual loss of the protective caps of our ...
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29
Telomere length and aging‐related outcomes in humans
https://onlinelibrary.wiley.com/doi/full/10.1111/acel.13017
Telomeres function to protect chromosome ends against genomic instability. Telomeres shorten with each cell cycle and contribute to replicative ...
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https://onlinelibrary.wiley.com/doi/full/10.1111/acel.13017
Telomeres function to protect chromosome ends against genomic instability. Telomeres shorten with each cell cycle and contribute to replicative ...
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30
Telomere Time—Why We Should Treat Biological Age ...
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2765370
Because these cells and the progenitor cells that give rise to them pass through the cell cycle, the measured length of their telomeres ...
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https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2765370
Because these cells and the progenitor cells that give rise to them pass through the cell cycle, the measured length of their telomeres ...
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31
Telomere length: biological marker of cellular vitality, aging ...
https://www.scielo.br/j/ramb/a/gMXVvdhpzH395myGC9KS5WH/
Telomeres are regions at the ends of chromosomes that play a role in the maintenance and integrity of DNA. With biological aging, telomere shortening occurs, ...
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https://www.scielo.br/j/ramb/a/gMXVvdhpzH395myGC9KS5WH/
Telomeres are regions at the ends of chromosomes that play a role in the maintenance and integrity of DNA. With biological aging, telomere shortening occurs, ...
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32
Telomere - Wikipedia
https://en.wikipedia.org/wiki/Telomere
Telomere · Discovery · Structure and function · Shortening · Lengthening · Sequences · Research on disease risk · Measurement · In wildlife ...
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https://en.wikipedia.org/wiki/Telomere
Telomere · Discovery · Structure and function · Shortening · Lengthening · Sequences · Research on disease risk · Measurement · In wildlife ...
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33
Telomere Length And Aging - Sierra Sciences
https://sierrasci.com/telomeres/
In many cases some tissues will experience increased rates of cell division during a person's life, resulting in accelerated telomere shortening and early ...
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https://sierrasci.com/telomeres/
In many cases some tissues will experience increased rates of cell division during a person's life, resulting in accelerated telomere shortening and early ...
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34
Telomere Shortening: Causes, and Consequences on Aging
http://www.longlonglife.org/en/transhumanism-longevity/aging/telomere-shortening-causes-consequences-on-aging/
Telomere shortening seems to be faster in men than in women. Telomere length being associated with age and with the aging process (see: ...
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http://www.longlonglife.org/en/transhumanism-longevity/aging/telomere-shortening-causes-consequences-on-aging/
Telomere shortening seems to be faster in men than in women. Telomere length being associated with age and with the aging process (see: ...
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35
Eight Tips to Help Maintain Telomere Length
https://aviishaaya.com/blog/eight-tips-to-help-maintain-telomere-length
When telomeres shorten, it tells your cells to regenerate less healthy cells and to produce mutations that can lead to cancer. The symptoms that ...
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https://aviishaaya.com/blog/eight-tips-to-help-maintain-telomere-length
When telomeres shorten, it tells your cells to regenerate less healthy cells and to produce mutations that can lead to cancer. The symptoms that ...
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36
Decline in telomere length by age and effect modification by ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221690
With each somatic cell division, there is a gradual attrition of the telomere, resulting in telomere length shortening with increasing age ...
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221690
With each somatic cell division, there is a gradual attrition of the telomere, resulting in telomere length shortening with increasing age ...
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37
Telomere Shortening in Kidneys with Age
https://jasn.asnjournals.org/content/11/3/444
We found that telomeres in human kidney cortex shorten with age, and that the shortening is faster in cortex than in medulla. These observations ...
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https://jasn.asnjournals.org/content/11/3/444
We found that telomeres in human kidney cortex shorten with age, and that the shortening is faster in cortex than in medulla. These observations ...
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38
Telomere position effect: regulation of gene expression with ...
http://genesdev.cshlp.org/content/28/22/2464.full.pdf
Our results suggest a potential novel mechanism for how telomere shortening could contribute to aging and disease initiation/progression in human cells long ...
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http://genesdev.cshlp.org/content/28/22/2464.full.pdf
Our results suggest a potential novel mechanism for how telomere shortening could contribute to aging and disease initiation/progression in human cells long ...
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39
Relative Telomere Length Is Associated With Age ... - IOVS
https://iovs.arvojournals.org/article.aspx?articleid=2778859
Premature shortening of telomeres is associated with oxidative stress, which is one possible pathway that might contribute to age-related macular degeneration ( ...
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https://iovs.arvojournals.org/article.aspx?articleid=2778859
Premature shortening of telomeres is associated with oxidative stress, which is one possible pathway that might contribute to age-related macular degeneration ( ...
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40
Telomere Attrition as Ageing Biomarker - Anticancer Research
https://ar.iiarjournals.org/content/anticanres/25/4/3011.full.pdf
Telomere shortening is associated with cellular senescence and is implicated in tumorigenesis and cancer. Hence, mean telomere length has emerged as a.
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https://ar.iiarjournals.org/content/anticanres/25/4/3011.full.pdf
Telomere shortening is associated with cellular senescence and is implicated in tumorigenesis and cancer. Hence, mean telomere length has emerged as a.
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41
What are telomeres? - Curious - Australian Academy of Science
https://www.science.org.au/curious/people-medicine/what-are-telomeres
This shortening is thought to be one of several factors that causes cells to age. A cell can no longer divide when telomeres are too ...
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https://www.science.org.au/curious/people-medicine/what-are-telomeres
This shortening is thought to be one of several factors that causes cells to age. A cell can no longer divide when telomeres are too ...
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42
Telomere shortening and ageing - Springer
https://link.springer.com/content/pdf/10.1007/s00391-007-0480-0.pdf
Telomere shortening and ageing. Z Gerontol Geriat 40:314–324 (2007). DOI 10.1007/s00391-007-0480-0. CONTRIBUTION TO THE MAIN TOPIC. Received: 16 July 2007.
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https://link.springer.com/content/pdf/10.1007/s00391-007-0480-0.pdf
Telomere shortening and ageing. Z Gerontol Geriat 40:314–324 (2007). DOI 10.1007/s00391-007-0480-0. CONTRIBUTION TO THE MAIN TOPIC. Received: 16 July 2007.
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43
Exploring Telomere Dynamics in Aging Male Rat Tissues
https://www.karger.com/Article/FullText/511608
Young thymus telomeres increased in length (3 vs. 12 weeks) and then shortened between 12 and 52 weeks (p < 0.001). We also reported disparity in telomere ...
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https://www.karger.com/Article/FullText/511608
Young thymus telomeres increased in length (3 vs. 12 weeks) and then shortened between 12 and 52 weeks (p < 0.001). We also reported disparity in telomere ...
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44
Physical Activity on Telomere Length as a Biomarker for Aging
https://sportsmedicine-open.springeropen.com/articles/10.1186/s40798-022-00503-1
Telomere attrition or shortening is a well-known molecular marker in aging. As such, several studies have focused on whether exercise ...
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https://sportsmedicine-open.springeropen.com/articles/10.1186/s40798-022-00503-1
Telomere attrition or shortening is a well-known molecular marker in aging. As such, several studies have focused on whether exercise ...
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45
DNA damage response at telomeres boosts the transcription ...
https://www.embopress.org/doi/10.15252/embr.202153658
During aging, telomeres progressively shorten and/or accumulate damage in several tissues and organs in different species including humans ( ...
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https://www.embopress.org/doi/10.15252/embr.202153658
During aging, telomeres progressively shorten and/or accumulate damage in several tissues and organs in different species including humans ( ...
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46
Aging-US: DNA- and telomere-damage does not l - EurekAlert!
https://www.eurekalert.org/pub_releases/2021-03/ijl-ada030221.php
While shortening lifespan by 18% in unnatural telomerase- deficient mice, in the same study in natural mice, rapamycin increased lifespan by 39% ...
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https://www.eurekalert.org/pub_releases/2021-03/ijl-ada030221.php
While shortening lifespan by 18% in unnatural telomerase- deficient mice, in the same study in natural mice, rapamycin increased lifespan by 39% ...
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47
Telomere Analysis - Metabolomic
https://www.metabolomicmedicine.com/english/telomere_analysis-na-192.html
Telomere shortening has been discovered to be the primary cause of human aging and aging related diseases such as cancer, autoimmunity and heart disease.
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https://www.metabolomicmedicine.com/english/telomere_analysis-na-192.html
Telomere shortening has been discovered to be the primary cause of human aging and aging related diseases such as cancer, autoimmunity and heart disease.
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48
What is a telomere? - YourGenome
https://www.yourgenome.org/facts/what-is-a-telomere/
Mice models lacking the enzyme telomerase were found to show signs of premature ageing. · However, it is not certain whether telomere shortening ...
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https://www.yourgenome.org/facts/what-is-a-telomere/
Mice models lacking the enzyme telomerase were found to show signs of premature ageing. · However, it is not certain whether telomere shortening ...
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49
Telomere Shortening and Stress - AZoLifeSciences
https://www.azolifesciences.com/article/Telomere-Shortening-and-Stress.aspx
Stress has even been reported to accelerate aging and the onset of age-related diseases. Recent research links both chronic and perceived stress ...
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https://www.azolifesciences.com/article/Telomere-Shortening-and-Stress.aspx
Stress has even been reported to accelerate aging and the onset of age-related diseases. Recent research links both chronic and perceived stress ...
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50
Telomere Shortening and Implications for Cancer and Aging ...
https://blogs.brandeis.edu/dnamechanisms/telomeres/crystal-nevins-2/
In humans, telomere shortening rates have been determined to be 20-60 bade pairs per year, depending on the tissue type. Telomeres have a dynamic structure and ...
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https://blogs.brandeis.edu/dnamechanisms/telomeres/crystal-nevins-2/
In humans, telomere shortening rates have been determined to be 20-60 bade pairs per year, depending on the tissue type. Telomeres have a dynamic structure and ...
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51
Telomere attrition with age in a wild amphibian population
https://royalsocietypublishing.org/doi/10.1098/rsbl.2020.0168
Net telomere shortening with age has been widely documented across taxa [1,5,6], although some studies have failed to find significant ...
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https://royalsocietypublishing.org/doi/10.1098/rsbl.2020.0168
Net telomere shortening with age has been widely documented across taxa [1,5,6], although some studies have failed to find significant ...
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52
Telomere Length Test - How Are Your Cells Aging?
https://cellsciencesystems.com/patients/telomere/
Inflammation is associated with aging and telomere shortening. Telomeres become shorter after each cell division until eventually chromosomal DNA reaches a ...
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https://cellsciencesystems.com/patients/telomere/
Inflammation is associated with aging and telomere shortening. Telomeres become shorter after each cell division until eventually chromosomal DNA reaches a ...
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53
Stress, Aging, and Telomeres - The American Institute of Stress
https://www.stress.org/stress-aging-and-telomeres
This shortening and eventual erosion of telomeres are prevented or reduced by telomerase, an enzyme in cells that preserves their length. Many ...
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https://www.stress.org/stress-aging-and-telomeres
This shortening and eventual erosion of telomeres are prevented or reduced by telomerase, an enzyme in cells that preserves their length. Many ...
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54
Telomere Shortening and Tumor Formation by Mouse Cells ...
https://www.cell.com/abstract/S0092-8674(01)80006-4
First, human telomeres are on average shorter than mouse telomeres. Telomere shortening and telomerase activation might play a role in human tumor growth and ...
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https://www.cell.com/abstract/S0092-8674(01)80006-4
First, human telomeres are on average shorter than mouse telomeres. Telomere shortening and telomerase activation might play a role in human tumor growth and ...
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55
Covid-19, susceptibility to Sars-CoV-2 linked to telomere ...
https://bioinst.com/en/covid-19-susceptibility-to-sars-cov-2-linked-to-telomere-shortening/
In the elderly, critically shortened telomeres are managed by the cell as damaged Dna. So, they trigger a DNA-damage response. Animal models ...
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https://bioinst.com/en/covid-19-susceptibility-to-sars-cov-2-linked-to-telomere-shortening/
In the elderly, critically shortened telomeres are managed by the cell as damaged Dna. So, they trigger a DNA-damage response. Animal models ...
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56
Heart-Breaking Telomeres | Circulation Research
https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.118.312202
Indeed, shorter telomere length has been shown to associate to major depressive disorder, a severe illness which shows signs of premature aging.
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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.118.312202
Indeed, shorter telomere length has been shown to associate to major depressive disorder, a severe illness which shows signs of premature aging.
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57
Anti-aging from Within: The Science of Telomeres
https://www.vitdripcenter.com/post/anti-aging-from-within-the-science-of-telomeres-vitdripcenter
Telomere shortening is involved in all aspects of the aging process on a cellular level. Telomere length represents our biological age as ...
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https://www.vitdripcenter.com/post/anti-aging-from-within-the-science-of-telomeres-vitdripcenter
Telomere shortening is involved in all aspects of the aging process on a cellular level. Telomere length represents our biological age as ...
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58
Previously Unknown Protective Role Uncovered for ...
https://www.genengnews.com/news/previously-unknown-protective-role-uncovered-for-telomerase-in-somatic-cell-aging/
This led the team to consider whether telomerase may play a role in somatic cell senescence and aging. “Based on this observation, we speculate ...
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https://www.genengnews.com/news/previously-unknown-protective-role-uncovered-for-telomerase-in-somatic-cell-aging/
This led the team to consider whether telomerase may play a role in somatic cell senescence and aging. “Based on this observation, we speculate ...
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59
Telomere Shortening Is a Sole Mechanism of Aging in Mammals
https://www.eurekaselect.com/article/49448
We postulate that if oxidative damage was entirely absent, telomeres would, nevertheless, shorten with each mitotic cycle because this is the mechanism of DNA ...
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https://www.eurekaselect.com/article/49448
We postulate that if oxidative damage was entirely absent, telomeres would, nevertheless, shorten with each mitotic cycle because this is the mechanism of DNA ...
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60
How can I protect my telomeres and slow aging? - De Gruyter
https://www.degruyter.com/document/doi/10.1515/tjb-2017-0319/html?lang=en
In humans, telomere length are heterogeneous among different chromosomes, accelerated telomere shortening is associated with early onset of age- ...
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https://www.degruyter.com/document/doi/10.1515/tjb-2017-0319/html?lang=en
In humans, telomere length are heterogeneous among different chromosomes, accelerated telomere shortening is associated with early onset of age- ...
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61
Telomere Length Provides a New Technique for Aging Animals
https://www.jstor.org/stable/4223174
Telomere length shortens with age in cultured cells and mouse and human tissues. We found that lengths of telomere restriction fragments cleaved from blood ...
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https://www.jstor.org/stable/4223174
Telomere length shortens with age in cultured cells and mouse and human tissues. We found that lengths of telomere restriction fragments cleaved from blood ...
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62
Anti-Aging from Within: The Science of Telomeres - Goop
https://goop.com/wellness/health/anti-aging-from-within-the-science-of-telomeres/
Telomeres are the caps at the ends of chromosomes that protect DNA from damage. As we age, they get shorter. When they get too short, the cell can go into ...
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https://goop.com/wellness/health/anti-aging-from-within-the-science-of-telomeres/
Telomeres are the caps at the ends of chromosomes that protect DNA from damage. As we age, they get shorter. When they get too short, the cell can go into ...
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63
Study identifies potential drug treatments for telomere diseases
https://news.harvard.edu/gazette/story/2020/04/study-identifies-potential-drug-treatments-for-telomere-diseases/
The compounds identified in the study restore telomeres, protective caps on the tips of our chromosomes that regulate how our cells age.
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https://news.harvard.edu/gazette/story/2020/04/study-identifies-potential-drug-treatments-for-telomere-diseases/
The compounds identified in the study restore telomeres, protective caps on the tips of our chromosomes that regulate how our cells age.
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64
Full article: Telomere length and cardiovascular aging
https://www.tandfonline.com/doi/full/10.3109/07853890.2012.660497
Leukocyte telomere length (LTL) shortening is inhibited by estrogen and endogenous antioxidants. Accelerated telomere attrition is associated with ...
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https://www.tandfonline.com/doi/full/10.3109/07853890.2012.660497
Leukocyte telomere length (LTL) shortening is inhibited by estrogen and endogenous antioxidants. Accelerated telomere attrition is associated with ...
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65
Telomerase treatment prevents lung profibrotic pathologies ...
https://rupress.org/jcb/article/219/10/e202002120/152010/Telomerase-treatment-prevents-lung-profibrotic
Telomere shortening can be compensated through the de novo addition of telomeric repeats onto chromosome ends by telomerase, a reverse ...
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https://rupress.org/jcb/article/219/10/e202002120/152010/Telomerase-treatment-prevents-lung-profibrotic
Telomere shortening can be compensated through the de novo addition of telomeric repeats onto chromosome ends by telomerase, a reverse ...
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66
Telomeres in aging and disease: lessons from zebrafish
https://journals.biologists.com/dmm/article/9/7/737/3792/Telomeres-in-aging-and-disease-lessons-from
Telomere shortening is thought to play a central role in the aging process in humans. The link between telomeres and aging is highlighted by the ...
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https://journals.biologists.com/dmm/article/9/7/737/3792/Telomeres-in-aging-and-disease-lessons-from
Telomere shortening is thought to play a central role in the aging process in humans. The link between telomeres and aging is highlighted by the ...
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67
First-Time Human Study Shows Reversal in Biology of Aging
https://www.prnewswire.com/il/news-releases/first-time-human-study-shows-reversal-in-biology-of-aging--telomere-shortening-and-senescent-cells-accumulation--with-hyperbaric-oxygen-therapy-hbot-301176053.html
The shortening of telomere length, of approximately 20-40 bases per year, which is associated with a variety of serious life-threatening ...
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https://www.prnewswire.com/il/news-releases/first-time-human-study-shows-reversal-in-biology-of-aging--telomere-shortening-and-senescent-cells-accumulation--with-hyperbaric-oxygen-therapy-hbot-301176053.html
The shortening of telomere length, of approximately 20-40 bases per year, which is associated with a variety of serious life-threatening ...
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68
Process of Ageing - the role of telomere - Age Watch
https://www.agewatch.net/ageing-why-and-how/process-of-ageing-the-role-o/
Telomere-shortening is a risk factor for numerous diseases and may be a general biomarker of ageing. There seems to be a clear association between the length of ...
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https://www.agewatch.net/ageing-why-and-how/process-of-ageing-the-role-o/
Telomere-shortening is a risk factor for numerous diseases and may be a general biomarker of ageing. There seems to be a clear association between the length of ...
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69
Anti-Aging Effects of Telomerase on Telomeres
http://www.betterfamilyhealth.org/Anti-aging-Cellular-Rejuvenation.html
Telomere shortening is involved in all aspects of the aging process on a cellular level. It is the main cause of age-related breakdown of your cells. When ...
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http://www.betterfamilyhealth.org/Anti-aging-Cellular-Rejuvenation.html
Telomere shortening is involved in all aspects of the aging process on a cellular level. It is the main cause of age-related breakdown of your cells. When ...
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70
Telomeres and Telomerase in Cellular Aging (Senescence)
https://embryo.asu.edu/pages/telomeres-and-telomerase-cellular-aging-senescence
As cells replicate, telomeres shorten at the end of chromosomes, and this process correlates to senescence or cellular aging.
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https://embryo.asu.edu/pages/telomeres-and-telomerase-cellular-aging-senescence
As cells replicate, telomeres shorten at the end of chromosomes, and this process correlates to senescence or cellular aging.
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71
Do telomere length tests really reveal your biological age?
https://www.newscientist.com/article/mg24933221-000-do-telomere-length-tests-really-reveal-your-biological-age/
If this shortening happens slowly, it suggests that your body is wearing well. Say you are a 60-year-old with telomeres as long as those of an ...
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https://www.newscientist.com/article/mg24933221-000-do-telomere-length-tests-really-reveal-your-biological-age/
If this shortening happens slowly, it suggests that your body is wearing well. Say you are a 60-year-old with telomeres as long as those of an ...
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72
Telomere length dynamics in aging mice
https://ir.lib.uwo.ca/cgi/viewcontent.cgi?article=2051&context=etd
Telomere shortening can be caused by DNA replication errors caused by mutations or malfunction of various proteins such as RecQ protein-like helicases (WRN and ...
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https://ir.lib.uwo.ca/cgi/viewcontent.cgi?article=2051&context=etd
Telomere shortening can be caused by DNA replication errors caused by mutations or malfunction of various proteins such as RecQ protein-like helicases (WRN and ...
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73
JCI - Telomeres and age-related disease
https://www.jci.org/articles/view/66370
Telomere syndromes have defined pathological ranges of telomere shortening. Although short telomere length (TL) has been associated with numerous conditions, in ...
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https://www.jci.org/articles/view/66370
Telomere syndromes have defined pathological ranges of telomere shortening. Although short telomere length (TL) has been associated with numerous conditions, in ...
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74
Aging: Too Much Telomerase Can Be as Bad as Too Little
https://blogs.scientificamerican.com/guest-blog/aging-too-much-telomerase-can-be-as-bad-as-too-little/
One of the central mechanisms responsible for the aging of cells is the shortening of telomeres. Telomeres are repetitive DNA sequences at ...
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https://blogs.scientificamerican.com/guest-blog/aging-too-much-telomerase-can-be-as-bad-as-too-little/
One of the central mechanisms responsible for the aging of cells is the shortening of telomeres. Telomeres are repetitive DNA sequences at ...
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75
Telomere shortening puts a limit on the number of times a cell ...
https://www.pearson.com/channels/biology/asset/4471850e
Telomerase will speed up the rate of cell division. B. Telomerase stops telomere shortening and slows or stops cellular aging. c) Telomerase shortens ...
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https://www.pearson.com/channels/biology/asset/4471850e
Telomerase will speed up the rate of cell division. B. Telomerase stops telomere shortening and slows or stops cellular aging. c) Telomerase shortens ...
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76
Syndromes Associated with Telomere Shortening | IntechOpen
https://www.intechopen.com/chapters/68983
Short telomeres are associated with early senescence, genomic instability, and apoptosis of cells. Short telomeres can result due to several factors including ...
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https://www.intechopen.com/chapters/68983
Short telomeres are associated with early senescence, genomic instability, and apoptosis of cells. Short telomeres can result due to several factors including ...
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77
A model linking ageing to COVID-19 T-cell lymphopenia and ...
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00162-1/fulltext
Although naïve T cells have some telomerase activity, it is insufficient to prevent their age-dependent telomere shortening, and ageing may thus ...
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https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00162-1/fulltext
Although naïve T cells have some telomerase activity, it is insufficient to prevent their age-dependent telomere shortening, and ageing may thus ...
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78
Theories on Aging - SPH - Boston University
https://sphweb.bumc.bu.edu/otlt/mph-modules/ph/aging/aging3.html
Telomeres are repeated nucleotides sequences on the end of chromosomes that are believed to protect the DNA strands and prevent them from fusing ...
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https://sphweb.bumc.bu.edu/otlt/mph-modules/ph/aging/aging3.html
Telomeres are repeated nucleotides sequences on the end of chromosomes that are believed to protect the DNA strands and prevent them from fusing ...
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79
Telomeres: Definition, Structure, Shortening and Role in Ageing
https://byjus.com/neet/telomeres/
Telomeres play a vital role in the ageing of the cells. With each replication, telomeres become shorter and shorter and when they become too short, the cells ...
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https://byjus.com/neet/telomeres/
Telomeres play a vital role in the ageing of the cells. With each replication, telomeres become shorter and shorter and when they become too short, the cells ...
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80
Telomere and its role in the aging pathways
http://bms.tmu.edu.cn/_upload/article/files/14/1a/e429e95d4542962ca734ea66c3ba/a4a3ccf8-b709-47ed-88ed-6ed79a292e01.pdf
Due to the mechanism of replication, telomeres shorten as cells proliferate, which consequently contributes to cellular senescence and mitochondrial dysfunction ...
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http://bms.tmu.edu.cn/_upload/article/files/14/1a/e429e95d4542962ca734ea66c3ba/a4a3ccf8-b709-47ed-88ed-6ed79a292e01.pdf
Due to the mechanism of replication, telomeres shorten as cells proliferate, which consequently contributes to cellular senescence and mitochondrial dysfunction ...
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81
Telomeres, Hormones and Aging - SpectraCell Laboratories
https://www.spectracell.com/blog/posts/bid-75358-telomeres-hormones-and-aging
Oxidative stress will shorten telomere length and cause aging in cellular tissue. Antioxidant supplements can potentially reduce oxidative stress very ...
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https://www.spectracell.com/blog/posts/bid-75358-telomeres-hormones-and-aging
Oxidative stress will shorten telomere length and cause aging in cellular tissue. Antioxidant supplements can potentially reduce oxidative stress very ...
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82
How telomeres contribute to the cellular mechanisms of aging
https://www.medicalnewstoday.com/articles/study-sheds-light-on-the-cellular-machinery-of-aging
Telomere shortening imposes a limit on the number of times a cell can divide. Sperm and egg cells are exceptions to this rule.
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https://www.medicalnewstoday.com/articles/study-sheds-light-on-the-cellular-machinery-of-aging
Telomere shortening imposes a limit on the number of times a cell can divide. Sperm and egg cells are exceptions to this rule.
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83
Scientists discover an on/off switch for aging cells - Salk Institute
https://www.salk.edu/news-release/scientists-discover-an-onoff-switch-for-aging-cells/
Understanding how this “off” switch can be manipulated–thereby slowing down the telomere shortening process–could lead to treatments for ...
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https://www.salk.edu/news-release/scientists-discover-an-onoff-switch-for-aging-cells/
Understanding how this “off” switch can be manipulated–thereby slowing down the telomere shortening process–could lead to treatments for ...
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84
What Is Telomere Attrition? - The Hallmarks Of Ageing Series
https://www.gowinglife.com/what-is-telomere-attrition-the-hallmarks-of-ageing-series/
Telomere exhaustion is observed in ageing and represents a type of molecular clock that drives the ageing process, progressively reducing the ...
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https://www.gowinglife.com/what-is-telomere-attrition-the-hallmarks-of-ageing-series/
Telomere exhaustion is observed in ageing and represents a type of molecular clock that drives the ageing process, progressively reducing the ...
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85
Aging and Telomere Length Quantification by qPCR
https://sciencellonline.com/blog/aging-and-telomere-length-quantification-by-qpcr/
Although telomerase acts to elongate telomeres to counteract this loss, over time telomere length still decreases. There is increasing evidence ...
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https://sciencellonline.com/blog/aging-and-telomere-length-quantification-by-qpcr/
Although telomerase acts to elongate telomeres to counteract this loss, over time telomere length still decreases. There is increasing evidence ...
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86
Higher dietary selenium intakes linked to younger 'biological ...
https://www.nutraingredients-usa.com/Article/2022/06/27/higher-dietary-selenium-intakes-linked-to-younger-biological-age-telomere-study
Telomeres. The aging and lifespan of normal, healthy cells are linked to the so-called telomerase shortening mechanism, which limits cells to a ...
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https://www.nutraingredients-usa.com/Article/2022/06/27/higher-dietary-selenium-intakes-linked-to-younger-biological-age-telomere-study
Telomeres. The aging and lifespan of normal, healthy cells are linked to the so-called telomerase shortening mechanism, which limits cells to a ...
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87
Effect of Physical Activity/Smoking/Sleep on Telomere Length
https://encyclopedia.pub/entry/17869
Telomere shortening is one of the most frequently studied mechanisms in the aging process. Telomere attrition reflects the cumulative load of oxidative, ...
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https://encyclopedia.pub/entry/17869
Telomere shortening is one of the most frequently studied mechanisms in the aging process. Telomere attrition reflects the cumulative load of oxidative, ...
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88
Telomeres and Aging: How to Keep Clients Younger Longer
https://www.skininc.com/science/physiology/article/21884238/telomeres-and-aging-how-to-keep-clients-younger-longer
When addressing skin aging with telomere length, inflammation is the key component that speeds up cell division more than is needed. Too much ...
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https://www.skininc.com/science/physiology/article/21884238/telomeres-and-aging-how-to-keep-clients-younger-longer
When addressing skin aging with telomere length, inflammation is the key component that speeds up cell division more than is needed. Too much ...
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89
A potential new treatment for premature aging diseases keeps ...
https://massivesci.com/articles/telomere-telomerase-rna-drug-premature-aging-stem-cell/
The ends of our DNA, called telomeres, get shorter as we age. Our cells lose a bit of telomere every time they divide. This shortening is a ...
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https://massivesci.com/articles/telomere-telomerase-rna-drug-premature-aging-stem-cell/
The ends of our DNA, called telomeres, get shorter as we age. Our cells lose a bit of telomere every time they divide. This shortening is a ...
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90
Why is Telomere Length Important in Aging?
https://www.longevitybynature.biz/why-is-telomere-length-important-in-aging/
The shorter the body's telomeres become, the greater the likelihood of aging-related disease. Telomere length works together with other factors such as ...
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https://www.longevitybynature.biz/why-is-telomere-length-important-in-aging/
The shorter the body's telomeres become, the greater the likelihood of aging-related disease. Telomere length works together with other factors such as ...
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91
Estimation of Human Age According to Telomere Shortening in...
https://journals.lww.com/amjforensicmedicine/fulltext/2009/09000/estimation_of_human_age_according_to_telomere.8.aspx
Changes with age in telomere lengths were assessed by Southern blotting. The results shown that telomeres shorten in human PBLs in an age-dependent manner ...
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https://journals.lww.com/amjforensicmedicine/fulltext/2009/09000/estimation_of_human_age_according_to_telomere.8.aspx
Changes with age in telomere lengths were assessed by Southern blotting. The results shown that telomeres shorten in human PBLs in an age-dependent manner ...
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92
Shortening of leucocyte telomere length is independently ...
https://drc.bmj.com/content/10/4/e002706
Leucocyte telomere length (LTL) is linked with aging and associated diseases, such as obesity, type 2 diabetes, and cardiovascular disease. WHAT THIS STUDY ADDS.
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https://drc.bmj.com/content/10/4/e002706
Leucocyte telomere length (LTL) is linked with aging and associated diseases, such as obesity, type 2 diabetes, and cardiovascular disease. WHAT THIS STUDY ADDS.
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93
EVIDENCE FOR BIOLOGICAL AGE ACCELERATION AND ...
https://www.medrxiv.org/content/10.1101/2021.04.23.21255973v1
A significant telomere shortening parallels this finding in the post-COVID19 cohort compared to COVID19-free subjects (post-COVID19 TL: 3,03 ...
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https://www.medrxiv.org/content/10.1101/2021.04.23.21255973v1
A significant telomere shortening parallels this finding in the post-COVID19 cohort compared to COVID19-free subjects (post-COVID19 TL: 3,03 ...
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94
Are Tiny Telomeres the Key to Aging? - WebMD
https://www.webmd.com/special-reports/anti-aging-science/20170419/telomere-aging-link
Telomeres wear down and get shorter over your lifetime, harming their ability to protect chromosomes. When this happens, new cells don't replace ...
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https://www.webmd.com/special-reports/anti-aging-science/20170419/telomere-aging-link
Telomeres wear down and get shorter over your lifetime, harming their ability to protect chromosomes. When this happens, new cells don't replace ...
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95
The Long and Short of Telomere Length and Diabetes
https://diabetesjournals.org/diabetes/article/63/1/65/17786/The-Long-and-Short-of-Telomere-Length-and-Diabetes
While telomeres are shorter in older age (5), the rate of telomere shortening varies among individuals (6). The association of shorter ...
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https://diabetesjournals.org/diabetes/article/63/1/65/17786/The-Long-and-Short-of-Telomere-Length-and-Diabetes
While telomeres are shorter in older age (5), the rate of telomere shortening varies among individuals (6). The association of shorter ...
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