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Google Keyword Rankings for : genetic kidney stone disease
1
Hereditary Causes of Kidney Stones and Chronic ... - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138059/
Though it meets the definition of a rare disease, cystinuria (OMIM 220100) is the most common cause of inherited kidney stones addressed in this ...
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138059/
Though it meets the definition of a rare disease, cystinuria (OMIM 220100) is the most common cause of inherited kidney stones addressed in this ...
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2
Kidney stones: MedlinePlus Genetics
https://medlineplus.gov/genetics/condition/kidney-stones/
Causes. Genetic changes can increase the risk of developing kidney stones, often acting in combination with a variety of environmental and ...
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https://medlineplus.gov/genetics/condition/kidney-stones/
Causes. Genetic changes can increase the risk of developing kidney stones, often acting in combination with a variety of environmental and ...
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3
Update on Hereditary Kidney Stone Disease and Introduction ...
https://www.frontiersin.org/articles/10.3389/fped.2018.00047/full
Calcium-based kidney stones account for the vast majority of cases, but their etiology is poorly understood, notably their genetic drivers. As ...
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https://www.frontiersin.org/articles/10.3389/fped.2018.00047/full
Calcium-based kidney stones account for the vast majority of cases, but their etiology is poorly understood, notably their genetic drivers. As ...
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4
When to suspect a genetic disorder in a patient with renal ...
https://academic.oup.com/ndt/article/28/4/811/1855589
Familial cases of renal stones are frequently observed in idiopathic calcium stone disease; in fact, a positive family history of ...
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https://academic.oup.com/ndt/article/28/4/811/1855589
Familial cases of renal stones are frequently observed in idiopathic calcium stone disease; in fact, a positive family history of ...
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5
Progress in Understanding the Genetics of Calcium ... - JASN
https://jasn.asnjournals.org/content/28/3/748
Most stones are calcium-containing, accounting for approximately 75% of all stones. Previous studies, in both twins and families with renal stones, have ...
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https://jasn.asnjournals.org/content/28/3/748
Most stones are calcium-containing, accounting for approximately 75% of all stones. Previous studies, in both twins and families with renal stones, have ...
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6
Kidney stones - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/kidney-stones/symptoms-causes/syc-20355755
Family or personal history. If someone in your family has had kidney stones, you're more likely to develop stones, too. If you've already had ...
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https://www.mayoclinic.org/diseases-conditions/kidney-stones/symptoms-causes/syc-20355755
Family or personal history. If someone in your family has had kidney stones, you're more likely to develop stones, too. If you've already had ...
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7
Dent Disease - National Organization for Rare Disorders
https://rarediseases.org/rare-diseases/dent-disease/
Dent disease is a rare genetic kidney disorder characterized by spillage of small proteins in the urine, increased levels of calcium in the urine, kidney ...
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https://rarediseases.org/rare-diseases/dent-disease/
Dent disease is a rare genetic kidney disorder characterized by spillage of small proteins in the urine, increased levels of calcium in the urine, kidney ...
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8
Genetics of kidney stone disease—Polygenic meets monogenic
https://www.sciencedirect.com/science/article/pii/S1769725520300109
Renal stones are common and are usually secondary to risk factors affecting the solubility of substances in the urinary tract. Primary, that is genetic, causes ...
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https://www.sciencedirect.com/science/article/pii/S1769725520300109
Renal stones are common and are usually secondary to risk factors affecting the solubility of substances in the urinary tract. Primary, that is genetic, causes ...
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9
Are kidney stones genetic? Diagnosis and prevention
https://www.medicalnewstoday.com/articles/are-kidney-stones-genetic
Kidney stones are hard objects that can form in the kidneys or bladder after certain chemicals build up in the body. Kidney stones may be ...
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https://www.medicalnewstoday.com/articles/are-kidney-stones-genetic
Kidney stones are hard objects that can form in the kidneys or bladder after certain chemicals build up in the body. Kidney stones may be ...
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10
The Genetics of Nephrolithiasis - FullText - Karger Publishers
https://www.karger.com/Article/Fulltext/151730
Renal stone formation is multifactorial, with environmental factors interacting with underlying genetic factors. Isolated genetic defects and ...
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https://www.karger.com/Article/Fulltext/151730
Renal stone formation is multifactorial, with environmental factors interacting with underlying genetic factors. Isolated genetic defects and ...
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11
Classical and Modern Genetic Approach to Kidney Stone ...
https://www.kireports.org/article/S2468-0249(19)30028-2/fulltext
Nephrolithiasis is one of the most widespread urinary disorders, and calcium, as calcium-oxalate or -phosphate, is by far the most frequent ...
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https://www.kireports.org/article/S2468-0249(19)30028-2/fulltext
Nephrolithiasis is one of the most widespread urinary disorders, and calcium, as calcium-oxalate or -phosphate, is by far the most frequent ...
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12
The genetics of kidney stone disease and nephrocalcinosis
https://mayoclinic.pure.elsevier.com/en/publications/the-genetics-of-kidney-stone-disease-and-nephrocalcinosis
Kidney stone formation results from an imbalance of inhibitors and promoters of crystallization, and calcium-containing calculi account for over 80% of stones.
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https://mayoclinic.pure.elsevier.com/en/publications/the-genetics-of-kidney-stone-disease-and-nephrocalcinosis
Kidney stone formation results from an imbalance of inhibitors and promoters of crystallization, and calcium-containing calculi account for over 80% of stones.
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13
Monogenic Kidney Stone - Genetic Testing - Full Text View
https://clinicaltrials.gov/ct2/show/NCT03305835
Family history of stones or nephrocalcinosis or unexplained kidney failure · Growth retardation · Metabolic bone disease · Unusual stone ...
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https://clinicaltrials.gov/ct2/show/NCT03305835
Family history of stones or nephrocalcinosis or unexplained kidney failure · Growth retardation · Metabolic bone disease · Unusual stone ...
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14
Are Kidney Stones Genetic? - Desiderio Avila Jr., MD
https://www.urophoenix.com/2019/01/18/are-kidney-stones-genetic/
This is a condition that causes too much calcium to build up in the urine. Too much calcium in the urine can promote a stone to form in a kidney ...
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https://www.urophoenix.com/2019/01/18/are-kidney-stones-genetic/
This is a condition that causes too much calcium to build up in the urine. Too much calcium in the urine can promote a stone to form in a kidney ...
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15
Genetics of common complex kidney stone disease
https://link.springer.com/article/10.1007/s00240-018-1094-2
Although genetic data have provided insights into the molecular basis of kidney stone disease, much remains to be learned about the ...
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https://link.springer.com/article/10.1007/s00240-018-1094-2
Although genetic data have provided insights into the molecular basis of kidney stone disease, much remains to be learned about the ...
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16
Polymorphisms in CaSR and CLDN14 Genes Associated with ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130790
The Arg990Gly (rs1042636) amino acid change, a rare gain of function variant of CaSR gene is strongly associated with kidney stone disease in ...
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130790
The Arg990Gly (rs1042636) amino acid change, a rare gain of function variant of CaSR gene is strongly associated with kidney stone disease in ...
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17
Molecular genetics of kidney stone disease - ThaiJO
https://li01.tci-thaijo.org/index.php/gst/article/download/16950/22825/59249
Genetic association study; Single nucleotide polymorphisms; Candidate gene. INTRODUCTION. Kidney stone disease (KSD) or nephrolithiasis is a formation of ...
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https://li01.tci-thaijo.org/index.php/gst/article/download/16950/22825/59249
Genetic association study; Single nucleotide polymorphisms; Candidate gene. INTRODUCTION. Kidney stone disease (KSD) or nephrolithiasis is a formation of ...
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18
Genetics of Kidney Stone Disease - YouTube
https://www.youtube.com/watch?v=JDwdhQXkEGo
Jul 16, 2021
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https://www.youtube.com/watch?v=JDwdhQXkEGo
Jul 16, 2021
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19
Kidney Stone Disease: Overview - UF Department of Urology
https://urology.ufl.edu/patient-care/stone-disease/
Cystinuria, a genetic disorder, is a rare (2%) but significant cause of nephrolithiasis. In addition to knowing a patient's stone type, it is important to ...
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https://urology.ufl.edu/patient-care/stone-disease/
Cystinuria, a genetic disorder, is a rare (2%) but significant cause of nephrolithiasis. In addition to knowing a patient's stone type, it is important to ...
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20
Kidney stones | 23andMe
https://www.23andme.com/topics/health-predispositions/kidney-stones
Are kidney stones genetic? ... Genetics does play a role in kidney stones. This means some people will be more likely to develop them based on their genetics.
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https://www.23andme.com/topics/health-predispositions/kidney-stones
Are kidney stones genetic? ... Genetics does play a role in kidney stones. This means some people will be more likely to develop them based on their genetics.
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21
Kidney Stones | Types, Causes, Symptoms, Diagnosis ...
https://www.cincinnatichildrens.org/health/k/kidney-stones
Cystine stones result from a genetic disorder where cystine leaks through the kidneys into the urine. Uric acid stones form when the urine has too much uric ...
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https://www.cincinnatichildrens.org/health/k/kidney-stones
Cystine stones result from a genetic disorder where cystine leaks through the kidneys into the urine. Uric acid stones form when the urine has too much uric ...
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22
The genetics of kidney stone disease and nephrocalcinosis.
https://europepmc.org/article/med/34907378
The advent of high-throughput sequencing techniques has enabled a monogenic cause of kidney stones to be identified in up to 30% of children and 10% of adults ...
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https://europepmc.org/article/med/34907378
The advent of high-throughput sequencing techniques has enabled a monogenic cause of kidney stones to be identified in up to 30% of children and 10% of adults ...
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23
Kidney stone treatment inches toward precision medicine
https://www.urologytimes.com/view/kidney-stone-treatment-inches-toward-precision-medicine
Although the etiology of kidney stone disease is multifactorial, emerging evidence suggests that the prevalence of genetically linked kidney ...
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https://www.urologytimes.com/view/kidney-stone-treatment-inches-toward-precision-medicine
Although the etiology of kidney stone disease is multifactorial, emerging evidence suggests that the prevalence of genetically linked kidney ...
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24
A rational approach to the use of sophisticated genetic ...
https://www.kidney-international.org/article/S0085-2538(17)30660-9/fulltext
The majority of inherited causes of recurrent kidney stones and/or nephrocalcinosis are autosomal recessive in nature and would be expected to ...
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https://www.kidney-international.org/article/S0085-2538(17)30660-9/fulltext
The majority of inherited causes of recurrent kidney stones and/or nephrocalcinosis are autosomal recessive in nature and would be expected to ...
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25
Kidney Stones | Northwestern Medicine
https://www.nm.org/conditions-and-care-areas/urology/kidney-stones
A rare genetic disorder called cystinuria can cause these stones. Cystinuria causes you to release many amino acids in the urine. This leads to kidney ...
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https://www.nm.org/conditions-and-care-areas/urology/kidney-stones
A rare genetic disorder called cystinuria can cause these stones. Cystinuria causes you to release many amino acids in the urine. This leads to kidney ...
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26
Kidney Stone Disease: An Update on Current Concepts
https://www.hindawi.com/journals/au/2018/3068365/
Kidney stone disease is a crystal concretion formed usually within the kidneys. It is an increasing urological disorder of human health, ...
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https://www.hindawi.com/journals/au/2018/3068365/
Kidney stone disease is a crystal concretion formed usually within the kidneys. It is an increasing urological disorder of human health, ...
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27
The genetics of kidney stone disease and nephrocalcinosis
https://www.researchgate.net/publication/357031938_The_genetics_of_kidney_stone_disease_and_nephrocalcinosis
... The pathogenesis of kidney stones is more complicated, with more predisposing variables such as dietary, metabolic, pharmacological, and environmental ...
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https://www.researchgate.net/publication/357031938_The_genetics_of_kidney_stone_disease_and_nephrocalcinosis
... The pathogenesis of kidney stones is more complicated, with more predisposing variables such as dietary, metabolic, pharmacological, and environmental ...
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28
Full article: Familiality of kidney stone disease in Iceland
https://www.tandfonline.com/doi/full/10.3109/00365590903151479
Objective. The aetiology of kidney stones is multifactorial, with environmental and genetic factors contributing to the pathogenesis. The aim of this study ...
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https://www.tandfonline.com/doi/full/10.3109/00365590903151479
Objective. The aetiology of kidney stones is multifactorial, with environmental and genetic factors contributing to the pathogenesis. The aim of this study ...
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29
Why some people are more prone to develop kidney stones
https://www.sciencedaily.com/releases/2012/04/120418203524.htm
But genes are partly to blame. A common genetic variation in a gene called claudin-14 recently has been linked to a substantial increase in risk ...
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https://www.sciencedaily.com/releases/2012/04/120418203524.htm
But genes are partly to blame. A common genetic variation in a gene called claudin-14 recently has been linked to a substantial increase in risk ...
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30
Future 'Exceedingly Bright' for Kidney Stone Prevention
https://www.medscape.com/viewarticle/958630
One of the most interesting directions for the medical management of stones lies in genetic investigations, said Preminger. "It is estimated ...
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https://www.medscape.com/viewarticle/958630
One of the most interesting directions for the medical management of stones lies in genetic investigations, said Preminger. "It is estimated ...
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31
A Drosophila genetic model of nephrolithiasis: transcriptional ...
https://bmcurol.biomedcentral.com/articles/10.1186/s12894-017-0292-5
Kidney stone is thought to be related to interaction of genetic factors and environment. In human renal stone disease, there are clear ...
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https://bmcurol.biomedcentral.com/articles/10.1186/s12894-017-0292-5
Kidney stone is thought to be related to interaction of genetic factors and environment. In human renal stone disease, there are clear ...
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32
Kidney stones in adults: Epidemiology and risk factors
https://www.uptodate.com/contents/kidney-stones-in-adults-epidemiology-and-risk-factors
Kidney stone disease (nephrolithiasis) is a common problem in primary care practice.This topic will review the epidemiology of kidney stones ...
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https://www.uptodate.com/contents/kidney-stones-in-adults-epidemiology-and-risk-factors
Kidney stone disease (nephrolithiasis) is a common problem in primary care practice.This topic will review the epidemiology of kidney stones ...
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33
Kidney stone disease - Wikipedia
https://en.wikipedia.org/wiki/Kidney_stone_disease
Most stones form by a combination of genetics and environmental factors. ... Risk factors include high urine calcium levels, obesity, certain foods, some ...
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https://en.wikipedia.org/wiki/Kidney_stone_disease
Most stones form by a combination of genetics and environmental factors. ... Risk factors include high urine calcium levels, obesity, certain foods, some ...
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34
Types of Kidney Stones - NYU Langone Health
https://nyulangone.org/conditions/kidney-stones/types
Cystine stones are caused by a hereditary genetic disorder called cystinuria that can lead to excessive amounts of the amino acid cystine collecting in the ...
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https://nyulangone.org/conditions/kidney-stones/types
Cystine stones are caused by a hereditary genetic disorder called cystinuria that can lead to excessive amounts of the amino acid cystine collecting in the ...
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35
Are Kidney Stones Genetic? - Xcode Life
https://www.xcode.life/genes-and-health/are-kidney-stones-genetic/
Two-thirds of people with calcium-based kidney stones have close relatives with the same condition. Kidney stones are influenced by genes.
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https://www.xcode.life/genes-and-health/are-kidney-stones-genetic/
Two-thirds of people with calcium-based kidney stones have close relatives with the same condition. Kidney stones are influenced by genes.
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36
Hereditary Calcium Oxalate Urolithiasis, Types 1 & 2
https://vetmed.umn.edu/research/labs/canine-genetics-lab/canine-genetic-testing/calcium-oxalate-urolithiasis-type-1
... are two different autosomal recessive genetic disorders that greatly increase the risk for formation of CaOx urinary (bladder or kidney) stones.
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https://vetmed.umn.edu/research/labs/canine-genetics-lab/canine-genetic-testing/calcium-oxalate-urolithiasis-type-1
... are two different autosomal recessive genetic disorders that greatly increase the risk for formation of CaOx urinary (bladder or kidney) stones.
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37
Kidney stone disease - The Journal of Clinical Investigation
https://www.jci.org/articles/view/26662
Dent disease. This X-linked hypercalciuric stone-forming disorder (Table 1) is due to mutations in the gene that codes for the voltage-gated ...
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https://www.jci.org/articles/view/26662
Dent disease. This X-linked hypercalciuric stone-forming disorder (Table 1) is due to mutations in the gene that codes for the voltage-gated ...
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38
Genetic variants of calcium and vitamin D metabolism in ...
https://www.biorxiv.org/content/10.1101/515882v1.full
Kidney stone disease (nephrolithiasis) is a major clinical and economic health burden with a multifactorial etiology and heritability of ~45-60% ...
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https://www.biorxiv.org/content/10.1101/515882v1.full
Kidney stone disease (nephrolithiasis) is a major clinical and economic health burden with a multifactorial etiology and heritability of ~45-60% ...
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39
understanding the clinical genetics of kidney stone disease ...
https://www.endourology.org/images/scholarships/2022/MichaelZhu.pdf
to better understand the most common underlying genetic causes of kidney stone formation using a new kidney disease-focused genetic test, the Natera® ...
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https://www.endourology.org/images/scholarships/2022/MichaelZhu.pdf
to better understand the most common underlying genetic causes of kidney stone formation using a new kidney disease-focused genetic test, the Natera® ...
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40
Inherited kidney diseases - Types and testing
https://www.kidney.org/atoz/content/inherited-kidney-disease
An inherited genetic disease that damages kidneys. Alport syndrome is caused by changes (mutations) in collagen protein genes. Collagen is an ...
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https://www.kidney.org/atoz/content/inherited-kidney-disease
An inherited genetic disease that damages kidneys. Alport syndrome is caused by changes (mutations) in collagen protein genes. Collagen is an ...
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41
Are Kidney Stones Genetic? | Decode your DNA and learn ...
https://nebula.org/blog/are-kidney-stones-genetic/
Are kidney stones hereditary? Although the inheritance pattern is unknown, it has been observed that those with a close relative (such as a parent or sibling) ...
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https://nebula.org/blog/are-kidney-stones-genetic/
Are kidney stones hereditary? Although the inheritance pattern is unknown, it has been observed that those with a close relative (such as a parent or sibling) ...
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42
Kidney Stones - CORE Kidney | UCLA Health
https://www.uclahealth.org/programs/core-kidney/conditions-treated/kidney-stones
It is estimated that 40% of patients with kidney stones are caused by inherited genetics. Listed below are a few rare genetic causes of kidney stones.
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https://www.uclahealth.org/programs/core-kidney/conditions-treated/kidney-stones
It is estimated that 40% of patients with kidney stones are caused by inherited genetics. Listed below are a few rare genetic causes of kidney stones.
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43
Genome‐Wide Analysis of Genes Related to Kidney Stone ...
https://asbmr.onlinelibrary.wiley.com/doi/full/10.1359/jbmr.081245
Urolithiasis is a multifactorial disease involving environmental and genetic factors. Calcium-containing kidney stones, which are >90% of ...
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https://asbmr.onlinelibrary.wiley.com/doi/full/10.1359/jbmr.081245
Urolithiasis is a multifactorial disease involving environmental and genetic factors. Calcium-containing kidney stones, which are >90% of ...
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44
Nephrolithiasis Panel - Blueprint Genetics
https://blueprintgenetics.com/tests/panels/metabolic-disorders/nephrolithiasis-panel/?pdf
Is ideal for patients with nephrolithiasis / hypercalciuria. About Nephrolithiasis. Nephrolithiasis (kidney stone disease), is a frequent disorder with a ...
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https://blueprintgenetics.com/tests/panels/metabolic-disorders/nephrolithiasis-panel/?pdf
Is ideal for patients with nephrolithiasis / hypercalciuria. About Nephrolithiasis. Nephrolithiasis (kidney stone disease), is a frequent disorder with a ...
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45
Genetic variants associated with kidney stones - Nature Portfolio
https://www.natureasia.com/en/life-sci/research/423
Individuals with certain CLDN14 variants can have a slightly increased risk of developing kidney stone disease compared to individuals who do ...
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https://www.natureasia.com/en/life-sci/research/423
Individuals with certain CLDN14 variants can have a slightly increased risk of developing kidney stone disease compared to individuals who do ...
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46
MP05-06 GENETIC ANALYSIS OF KIDNEY STONE DISEASE ...
https://www.auajournals.org/doi/10.1097/JU.0000000000002522.06
May 1, 2022 —
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https://www.auajournals.org/doi/10.1097/JU.0000000000002522.06
May 1, 2022 —
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47
kidney stone disease, V-ATPase models - FlyBase
https://flybase.org/reports/FBhh0001281.html
This report describes genetic models of calcium oxalate kidney stone disease in Drosophila. Mutations in human genes ATP6V1B1 and ATP6V0A4 have been ...
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https://flybase.org/reports/FBhh0001281.html
This report describes genetic models of calcium oxalate kidney stone disease in Drosophila. Mutations in human genes ATP6V1B1 and ATP6V0A4 have been ...
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48
Inherited Kidney Disease: Symptoms, Diagnosis, and Treatment
https://www.upmc.com/services/kidney-disease/conditions/inherited-kidney-disease
The most common hereditary kidney disease is autosomal dominant polycystic kidney disease (ADPKD). People with ADPKD form cysts on their kidneys. The cysts fill ...
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https://www.upmc.com/services/kidney-disease/conditions/inherited-kidney-disease
The most common hereditary kidney disease is autosomal dominant polycystic kidney disease (ADPKD). People with ADPKD form cysts on their kidneys. The cysts fill ...
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49
What Causes Kidney Stones? 12 Possible Causes - WebMD
https://www.webmd.com/kidney-stones/kidney-stone-causes
Certain genetic diseases. One example is medullary sponge kidney, a birth defect that causes cysts to form in the kidneys. Type ...
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https://www.webmd.com/kidney-stones/kidney-stone-causes
Certain genetic diseases. One example is medullary sponge kidney, a birth defect that causes cysts to form in the kidneys. Type ...
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50
Genetics & Kidney Disease
https://unckidneycenter.org/kidneyhealthlibrary/genetics-kidney-disease-1/
Some diseases in the kidneys are caused by problems (mutations) in genes. People have about 25,000-30,000 genes. The genes are made of DNA (deoxyribonucleic ...
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https://unckidneycenter.org/kidneyhealthlibrary/genetics-kidney-disease-1/
Some diseases in the kidneys are caused by problems (mutations) in genes. People have about 25,000-30,000 genes. The genes are made of DNA (deoxyribonucleic ...
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51
Kidney Stones: Symptoms, Causes, Diagnosis, Treatment ...
https://my.clevelandclinic.org/health/diseases/15604-kidney-stones
Are kidney stones genetic (hereditary)?. Yes, kidney stones can run in families. What's the urinary tract? How does it work? Your urinary tract ...
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https://my.clevelandclinic.org/health/diseases/15604-kidney-stones
Are kidney stones genetic (hereditary)?. Yes, kidney stones can run in families. What's the urinary tract? How does it work? Your urinary tract ...
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52
Nephrolithiasis and Nephrocalcinosis Panel - GeneDx
https://www.genedx.com/Resources/TIS-Files/TIS-TH01.pdf
DISORDER ALSO KNOWN AS. Kidney Stones; Renal Calculi; Urolithiasis. PANEL GENE LIST (41 GENES). ADCY10, AGXT, ALPL, AP2S1, APRT, ATP6V0A4, ATP6V1B1, BSND, ...
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https://www.genedx.com/Resources/TIS-Files/TIS-TH01.pdf
DISORDER ALSO KNOWN AS. Kidney Stones; Renal Calculi; Urolithiasis. PANEL GENE LIST (41 GENES). ADCY10, AGXT, ALPL, AP2S1, APRT, ATP6V0A4, ATP6V1B1, BSND, ...
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53
Kidney Stones: Medical Mangement Guideline
https://www.auanet.org/guidelines-and-quality/guidelines/kidney-stones-medical-mangement-guideline
Kidney stone disease is a common malady, affecting nearly 1 in 11 individuals in the United States at some point in their lives, and there is evidence that ...
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https://www.auanet.org/guidelines-and-quality/guidelines/kidney-stones-medical-mangement-guideline
Kidney stone disease is a common malady, affecting nearly 1 in 11 individuals in the United States at some point in their lives, and there is evidence that ...
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54
Kidney Stones | Johns Hopkins Medicine
https://www.hopkinsmedicine.org/health/conditions-and-diseases/kidney-stones
Cystine stones: Cystine stones are rare, and they form only in persons with an inherited metabolic disorder that causes high levels of cystine in the urine, a ...
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https://www.hopkinsmedicine.org/health/conditions-and-diseases/kidney-stones
Cystine stones: Cystine stones are rare, and they form only in persons with an inherited metabolic disorder that causes high levels of cystine in the urine, a ...
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55
The fruit fly kidney stone models and their application in drug ...
https://www.cell.com/heliyon/pdf/S2405-8440(22)00520-5.pdf
stones have been successfully established through dietary or genetic approaches in ... Kidney stone disease (Nephrolithiasis) refers to solid objects forma-.
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https://www.cell.com/heliyon/pdf/S2405-8440(22)00520-5.pdf
stones have been successfully established through dietary or genetic approaches in ... Kidney stone disease (Nephrolithiasis) refers to solid objects forma-.
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56
PH1: A Metabolic Kidney Stone Disease | Behind the Stone™
https://www.aboutph1.com/
Primary hyperoxaluria type 1 (PH1) is a rare, progressive inherited disease that can lead to kidney function decline.
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https://www.aboutph1.com/
Primary hyperoxaluria type 1 (PH1) is a rare, progressive inherited disease that can lead to kidney function decline.
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57
Genetics of common complex kidney stone disease - IRIS
https://iris.rais.is/is/publications/genetics-of-common-complex-kidney-stone-disease-insights-from-gen
Kidney stone disease is a common disorder in Western countries that is associated with significant suffering, morbidity, and cost for the healthcare system.
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https://iris.rais.is/is/publications/genetics-of-common-complex-kidney-stone-disease-insights-from-gen
Kidney stone disease is a common disorder in Western countries that is associated with significant suffering, morbidity, and cost for the healthcare system.
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58
Kidney stones Information | Mount Sinai - New York
https://www.mountsinai.org/health-library/report/kidney-stones
Often, the cause of calcium stones is not known and is referred to as idiopathic (of unknown cause) nephrolithiasis. Research suggests that nearly all stones ...
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https://www.mountsinai.org/health-library/report/kidney-stones
Often, the cause of calcium stones is not known and is referred to as idiopathic (of unknown cause) nephrolithiasis. Research suggests that nearly all stones ...
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59
Are Kidney Stones Inherited? - HealthMatch
https://healthmatch.io/kidney-disease/are-kidney-stones-genetic
Kidney stones have many potential causes, but heredity may be a factor. People who have an immediate family member with kidney stones are more ...
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https://healthmatch.io/kidney-disease/are-kidney-stones-genetic
Kidney stones have many potential causes, but heredity may be a factor. People who have an immediate family member with kidney stones are more ...
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60
Genetics of Kidney Stones
https://inkidney.com/genetics-of-kidney-stones/
Kidney stone development is the composite end-result of multiple factors including genetic, dietary and environmental, and can have serious consequences.
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https://inkidney.com/genetics-of-kidney-stones/
Kidney stone development is the composite end-result of multiple factors including genetic, dietary and environmental, and can have serious consequences.
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61
Genetic link to kidney stones identified - Newcastle University
https://www.ncl.ac.uk/press/articles/archive/2014/10/geneticlinktokidneystonesidentified.html
Dr Sayer said: “Previously it was thought that about 1% of kidney stone cases were caused by genetic disease. But this study shows that genetic ...
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https://www.ncl.ac.uk/press/articles/archive/2014/10/geneticlinktokidneystonesidentified.html
Dr Sayer said: “Previously it was thought that about 1% of kidney stone cases were caused by genetic disease. But this study shows that genetic ...
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62
Channing Kidney Stone Disease Research
https://www.brighamandwomens.org/research/departments/channing-division-of-network-medicine/kidney-stone-disease
Kidney stone disease (nephrolithiasis) affects more than 19 million U.S. adults and tens of millions more worldwide. Although rarely fatal, the morbidity and ...
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https://www.brighamandwomens.org/research/departments/channing-division-of-network-medicine/kidney-stone-disease
Kidney stone disease (nephrolithiasis) affects more than 19 million U.S. adults and tens of millions more worldwide. Although rarely fatal, the morbidity and ...
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63
Kidney stone disease: pathophysiology, investigation and ...
https://www.rcpjournals.org/content/clinmedicine/12/5/467
Kidney stone disease: pathophysiology, investigation and medical treatment · Risk factors. Low fluid intake · Factors contributing to high urine oxalate. Most ...
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https://www.rcpjournals.org/content/clinmedicine/12/5/467
Kidney stone disease: pathophysiology, investigation and medical treatment · Risk factors. Low fluid intake · Factors contributing to high urine oxalate. Most ...
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64
There are four main types of kidney stones
https://www.urologyhealth.org/documents/Product-Store/English/Kidney-Stones-Poster.pdf
Stones in the kidney often do not cause any symptoms. However, when a stone ... Kidney stone disease is one ... genetic kidney disease called cystinuria.
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https://www.urologyhealth.org/documents/Product-Store/English/Kidney-Stones-Poster.pdf
Stones in the kidney often do not cause any symptoms. However, when a stone ... Kidney stone disease is one ... genetic kidney disease called cystinuria.
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65
Classical and Modern Genetic Approach ... - Semantic Scholar
https://www.semanticscholar.org/paper/Classical-and-Modern-Genetic-Approach-to-Kidney-Vezzoli-Arcidiacono/b78d706df71a5dde0d47e1e9bec744153270ccfc
Abstract Significantly higher frequencies of renal calculi were found among the 625 parents and sibs of 106 subjects prone to calcium oxalate ...
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https://www.semanticscholar.org/paper/Classical-and-Modern-Genetic-Approach-to-Kidney-Vezzoli-Arcidiacono/b78d706df71a5dde0d47e1e9bec744153270ccfc
Abstract Significantly higher frequencies of renal calculi were found among the 625 parents and sibs of 106 subjects prone to calcium oxalate ...
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66
Genes may help to explain why kidney stones come back
https://www.kidneyresearchuk.org/2019/11/15/genes-may-help-to-explain-why-kidney-stones-come-back/
We can also observe that kidney stones often run in families - that is, you're more likely to develop kidney stone disease if a direct relative ...
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https://www.kidneyresearchuk.org/2019/11/15/genes-may-help-to-explain-why-kidney-stones-come-back/
We can also observe that kidney stones often run in families - that is, you're more likely to develop kidney stone disease if a direct relative ...
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67
Hereditary Tubulopathy and Nephrolithiasis Panel
https://dnatesting.uchicago.edu/tests/hereditary-tubulopathy-and-nephrolithiasis-panel-0
Kidney stone disease (or nephrolithiasis) is an increasingly prevalent condition with remarkable clinical heterogeneity, with regards to stone composition, ...
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https://dnatesting.uchicago.edu/tests/hereditary-tubulopathy-and-nephrolithiasis-panel-0
Kidney stone disease (or nephrolithiasis) is an increasingly prevalent condition with remarkable clinical heterogeneity, with regards to stone composition, ...
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68
Kidney Stones: Causes, Symptoms and treatment options
https://www.kidneyfund.org/all-about-kidneys/other-kidney-problems/kidney-stones
When there is too much cystine in your urine, kidney stones can form. These stones can get stuck in your kidneys, bladder or anywhere in your ...
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https://www.kidneyfund.org/all-about-kidneys/other-kidney-problems/kidney-stones
When there is too much cystine in your urine, kidney stones can form. These stones can get stuck in your kidneys, bladder or anywhere in your ...
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69
In vivo Drosophilia genetic model for calcium oxalate ...
https://journals.physiology.org/doi/full/10.1152/ajprenal.00074.2012
Up to 75% of human kidney stones are made of calcium oxalate (CaOx). Some of these CaOx stones are associated with rare genetic disorders (primary ...
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https://journals.physiology.org/doi/full/10.1152/ajprenal.00074.2012
Up to 75% of human kidney stones are made of calcium oxalate (CaOx). Some of these CaOx stones are associated with rare genetic disorders (primary ...
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70
Kidney Stones Are Prevalent in Individuals with Pseudoxantho...
https://journals.lww.com/ijdv/fulltext/2020/12000/kidney_stones_are_prevalent_in_individuals_with.2.aspx
Pseudoxanthoma elasticum (PXE) is a rare genetic disorder caused by loss-of-function mutations in the ABCC6 gene. While PXE is characterized by ectopic ...
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https://journals.lww.com/ijdv/fulltext/2020/12000/kidney_stones_are_prevalent_in_individuals_with.2.aspx
Pseudoxanthoma elasticum (PXE) is a rare genetic disorder caused by loss-of-function mutations in the ABCC6 gene. While PXE is characterized by ectopic ...
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71
Alnylam Act® Primary Hyperoxaluria Type 1 - Invitae
https://www.invitae.com/en/sponsored-testing/alnylam-act-hyperoxaluria-type-1
PH1 is a progressive genetic disease that is potentially life-threatening and often presents with calcium oxalate kidney stones.
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https://www.invitae.com/en/sponsored-testing/alnylam-act-hyperoxaluria-type-1
PH1 is a progressive genetic disease that is potentially life-threatening and often presents with calcium oxalate kidney stones.
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72
Kidney stone disease and cardiovascular events: a study on ...
https://tau.amegroups.com/article/view/85916/html
Background: Kidney stone disease (KSD) has been reported to be associated with several cardiovascular diseases. However, the causality between the ...
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https://tau.amegroups.com/article/view/85916/html
Background: Kidney stone disease (KSD) has been reported to be associated with several cardiovascular diseases. However, the causality between the ...
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73
Kidney stones - Causes - NHS
https://www.nhs.uk/conditions/kidney-stones/causes/
Types of kidney stones · calcium stones, the most common type of stone · struvite stones, usually caused by an infection, like a urine infection · uric acid stones ...
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https://www.nhs.uk/conditions/kidney-stones/causes/
Types of kidney stones · calcium stones, the most common type of stone · struvite stones, usually caused by an infection, like a urine infection · uric acid stones ...
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74
Special Issue : Genetics and Epigenetics of Kidney Diseases
https://www.mdpi.com/journal/biomedicines/special_issues/Epigenetics_Kidney
Besides monogenic inherited diseases, there are some genetic variations (e.g., APOL1 genes) that are linked to increased risk of developing kidney diseases ( ...
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https://www.mdpi.com/journal/biomedicines/special_issues/Epigenetics_Kidney
Besides monogenic inherited diseases, there are some genetic variations (e.g., APOL1 genes) that are linked to increased risk of developing kidney diseases ( ...
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75
Nephrolithiasis (Kidney Stones) - Ada Health
https://ada.com/conditions/nephrolithiasis/
Cystine stones are rare and may be caused by genetic factors that cause the body to reabsorb cystine, ornithine, lysine and arginine from the ...
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https://ada.com/conditions/nephrolithiasis/
Cystine stones are rare and may be caused by genetic factors that cause the body to reabsorb cystine, ornithine, lysine and arginine from the ...
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76
Kidney Stones: What's Your Risk? - Hawaii Pacific Health
https://www.hawaiipacifichealth.org/healthier-hawaii/be-healthy/kidney-stones-what-s-your-risk/
A genetic predisposition to kidney stones. Recurrent infections in the urine. Metabolic abnormalities that alter the electrolytes in the ...
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https://www.hawaiipacifichealth.org/healthier-hawaii/be-healthy/kidney-stones-what-s-your-risk/
A genetic predisposition to kidney stones. Recurrent infections in the urine. Metabolic abnormalities that alter the electrolytes in the ...
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77
Kidney Stone Disease
https://www.aymedilac.com/en-us/9-kidney-stone-disease.html
Although there are many factors that play a role in the formation of a stone in a person, the precise reason is not fully known. Genetic susceptibility is one ...
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https://www.aymedilac.com/en-us/9-kidney-stone-disease.html
Although there are many factors that play a role in the formation of a stone in a person, the precise reason is not fully known. Genetic susceptibility is one ...
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78
Childhood Kidney Stones: Their Surprising Connection to ...
https://pediatricsnationwide.org/2016/10/18/childhood-kidney-stones-their-surprising-connection-to-future-disease/
Once thought to be an adult condition, urinary stone disease is increasingly found in children – and may be related to the development of ...
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https://pediatricsnationwide.org/2016/10/18/childhood-kidney-stones-their-surprising-connection-to-future-disease/
Once thought to be an adult condition, urinary stone disease is increasingly found in children – and may be related to the development of ...
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79
Nephrolithiasis - Kidney Stone Disease | Choose the Right Test
https://arupconsult.com/content/nephrolithiasis
Kidney stones (renal calculi) present with hematuria, flank pain, or back pain, which can occur in other conditions, including infection and obstruction of ...
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https://arupconsult.com/content/nephrolithiasis
Kidney stones (renal calculi) present with hematuria, flank pain, or back pain, which can occur in other conditions, including infection and obstruction of ...
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80
Kidney Stones | Boston Children's Hospital
https://www.childrenshospital.org/conditions/kidney-stones
Some rare stone diseases can result from inborn metabolic problems, which means that the child has a genetic condition that causes their body to make these ...
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https://www.childrenshospital.org/conditions/kidney-stones
Some rare stone diseases can result from inborn metabolic problems, which means that the child has a genetic condition that causes their body to make these ...
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81
Genetic Kidney Disorders | Henry Ford Health - Detroit, MI
https://www.henryford.com/services/kidney/genetic-kidney-disorders
Your genetic makeup makes you susceptible to kidney disorders and other diseases like heart disease and cancer. Some kidney disorders are passed down from ...
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https://www.henryford.com/services/kidney/genetic-kidney-disorders
Your genetic makeup makes you susceptible to kidney disorders and other diseases like heart disease and cancer. Some kidney disorders are passed down from ...
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82
Family History Influences Kidney Stone Risk
https://www.renalandurologynews.com/home/conference-highlights/aua-2021/how-heredity-influences-kidney-stone-formers-onset-severity/
“There is an association between mitochondrial dysfunction and kidney stone disease,” Dr Unno explained. “Maternal inheritance of abnormal ...
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https://www.renalandurologynews.com/home/conference-highlights/aua-2021/how-heredity-influences-kidney-stone-formers-onset-severity/
“There is an association between mitochondrial dysfunction and kidney stone disease,” Dr Unno explained. “Maternal inheritance of abnormal ...
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83
A Retrospective Study of Kidney Stone Recurrence in Adults
https://www.jocmr.org/index.php/JOCMR/article/view/3753/25892842
Nephrolithiasis or kidney stone disease (KSD) is a common disorder estimated to affect approximately 10-12% of men and 5-6% of women in Western countries [1, 2] ...
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https://www.jocmr.org/index.php/JOCMR/article/view/3753/25892842
Nephrolithiasis or kidney stone disease (KSD) is a common disorder estimated to affect approximately 10-12% of men and 5-6% of women in Western countries [1, 2] ...
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84
Inherited Kidney Conditions | Michigan Medicine
https://www.uofmhealth.org/conditions-treatments/kidney/inherited-kidney-conditions
Evaluation of Inherited Kidney Diseases · Autosomal Dominant Polycystic Kidney Disease (ADPKD): The most common inherited kidney illness, ADPKD causes cysts to ...
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https://www.uofmhealth.org/conditions-treatments/kidney/inherited-kidney-conditions
Evaluation of Inherited Kidney Diseases · Autosomal Dominant Polycystic Kidney Disease (ADPKD): The most common inherited kidney illness, ADPKD causes cysts to ...
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85
Progress in Understanding the Genetics of Calcium ...
https://read.qxmd.com/read/27932479/progress-in-understanding-the-genetics-of-calcium-containing-nephrolithiasis
Renal stone disease is a frequent condition, causing a huge burden on health care systems globally. Calcium-based calculi account for around 75% of renal ...
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https://read.qxmd.com/read/27932479/progress-in-understanding-the-genetics-of-calcium-containing-nephrolithiasis
Renal stone disease is a frequent condition, causing a huge burden on health care systems globally. Calcium-based calculi account for around 75% of renal ...
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86
What causes kidney stones (and what to do) - Harvard Health
https://www.health.harvard.edu/blog/what-causes-kidney-stones-and-what-to-do-2019051716656
Cystinuria is a genetic condition. It results in high levels of cystine (an amino acid) in the urine, which then forms into kidney stones. Most ...
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https://www.health.harvard.edu/blog/what-causes-kidney-stones-and-what-to-do-2019051716656
Cystinuria is a genetic condition. It results in high levels of cystine (an amino acid) in the urine, which then forms into kidney stones. Most ...
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87
Kidney Stone: Symptoms, Causes, Treatment, and More
https://www.healthline.com/health/kidney-stones
Kidney stones, or renal calculi, are solid masses made of crystals. Kidney stones usually originate in your kidneys. However, they can develop anywhere along ...
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https://www.healthline.com/health/kidney-stones
Kidney stones, or renal calculi, are solid masses made of crystals. Kidney stones usually originate in your kidneys. However, they can develop anywhere along ...
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88
Kidney Stones | Children's Hospital of Philadelphia
https://www.chop.edu/conditions-diseases/kidney-stones
Renal stone disease accounts for 7-10 out of every 1,000 hospital admissions. Diet, genetics and lifestyle can all contribute to kidney stones. Several risk ...
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https://www.chop.edu/conditions-diseases/kidney-stones
Renal stone disease accounts for 7-10 out of every 1,000 hospital admissions. Diet, genetics and lifestyle can all contribute to kidney stones. Several risk ...
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89
Kidney stones - Osmosis
https://www.osmosis.org/learn/Kidney_stones
For the calcium oxalate stones, hyperoxaluria is a risk factor as well, and it can be due to a genetic defect that increases oxalate excretion, a defect in ...
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https://www.osmosis.org/learn/Kidney_stones
For the calcium oxalate stones, hyperoxaluria is a risk factor as well, and it can be due to a genetic defect that increases oxalate excretion, a defect in ...
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90
FDA Approves the First Drug to Treat an Rare Genetic ...
https://www.medindia.net/news/fda-approves-the-first-drug-to-treat-an-rare-genetic-disorder-which-causes-kidney-stones-198638-1.htm
PH1 causes recurrent kidney stones and loss of kidney function. Primary hyperoxalurias (PH) are caused due to over production of oxalates.
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https://www.medindia.net/news/fda-approves-the-first-drug-to-treat-an-rare-genetic-disorder-which-causes-kidney-stones-198638-1.htm
PH1 causes recurrent kidney stones and loss of kidney function. Primary hyperoxalurias (PH) are caused due to over production of oxalates.
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91
The Risk Factors and Symptoms for Kidney Stones
https://www.piedmont.org/living-better/what-is-a-kidney-stone
Kidney stones can be hereditary or they can be caused by other factors, such as: Being an adult. Being a male. Chronic diarrhea · Dehydration. Diet high in ...
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https://www.piedmont.org/living-better/what-is-a-kidney-stone
Kidney stones can be hereditary or they can be caused by other factors, such as: Being an adult. Being a male. Chronic diarrhea · Dehydration. Diet high in ...
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92
How Genetic Testing for Chronic Kidney Disease Improves ...
https://clpmag.com/diagnostic-technologies/molecular-diagnostics/sequencing-systems/how-genetic-testing-for-chronic-kidney-disease-improves-transplant-success/
More than 600 genes are known to be associated with monogenic chronic kidney disease and kidney failure, and it's usually very difficult to ...
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https://clpmag.com/diagnostic-technologies/molecular-diagnostics/sequencing-systems/how-genetic-testing-for-chronic-kidney-disease-improves-transplant-success/
More than 600 genes are known to be associated with monogenic chronic kidney disease and kidney failure, and it's usually very difficult to ...
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93
StoneDisease.org | Mission Pharmacal Company
https://www.stonedisease.org/
Understanding Kidney Stone Disease. Welcome. Stone disease is a painful and common condition that affects more than 5% of all adults in the US.1 It's ...
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https://www.stonedisease.org/
Understanding Kidney Stone Disease. Welcome. Stone disease is a painful and common condition that affects more than 5% of all adults in the US.1 It's ...
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94
Kidney Stones in Children - News Medical
https://www.news-medical.net/health/Kidney-Stones-in-Children.aspx
When the urine of a child has more uric acid, uric acid stones are formed. Some inherited disorders and certain medical conditions can increase the ...
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https://www.news-medical.net/health/Kidney-Stones-in-Children.aspx
When the urine of a child has more uric acid, uric acid stones are formed. Some inherited disorders and certain medical conditions can increase the ...
→ Check Latest Keyword Rankings ←
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