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1 Onset of Orolingual Angioedema After Treatment of Acute ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842699/
Alteplase is used to treat acute ischemic stroke. However, it has several documented adverse effects, including the development of orolingual angioedema (OA).
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2 ALTEPLASE-ASSOCIATED ANGIOEDEMA - CHEST Journal
https://journal.chestnet.org/article/S0012-3692(21)02230-3/fulltext
INTRODUCTION: Alteplase (recombinant tissue plasminogen activator or tPA) has revolutionized the management of acute ischemic stroke since ...
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3 Angioedema in Stroke Patients With Thrombolysis
https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.025260
Orolingual angioedema after alteplase therapy of acute ischaemic stroke: incidence and risk of prior angiotensin-converting enzyme inhibitor ...
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4 Management of Angioedema Due to Alteplase
https://www.universityhealthsystem.com/-/media/Files/Clinical-Pathways/Management-angioedmema-TPA-052015.ashx
Management of Angioedema Due to Alteplase. Early Diagnosis is Key. Incidence: Estimated 1% to 2% of all alteplase treated stroke.
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5 Angioedema after thrombolysis with tissue plasminogen ...
https://academic.oup.com/omcr/article/2019/1/omy112/5299969
Angioedema secondary to administration of rtPA is thought to be bradykinin ... Hemi-orolingual angioedema and ACE inhibition after alteplase ...
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6 Intravenous thrombolytic therapy for acute ischemic stroke
https://www.uptodate.com/contents/intravenous-thrombolytic-therapy-for-acute-ischemic-stroke-therapeutic-use
Hemi-orolingual angioedema and ACE inhibition after alteplase treatment of stroke. Neurology 2003; 60:1525. Chodirker WB.
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7 Anaphylactoid reactions and angioedema during ... - CMAJ
https://www.cmaj.ca/content/162/9/1281
Anaphylaxis and angioedema during alteplase infusion are likely caused by the activation of the complement and kinin cascades.13 Although ...
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8 Icatibant as a Potential Treatment of Life-Threatening ...
https://www.strokejournal.org/article/S1052-3057(17)30523-2/fulltext
Orolingual angioedema is a life-threatening complication of alteplase treatment for acute ischemic stroke that occurs during alteplase infusion ...
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9 Orolingual angioedema to alteplase. Identify, counsel and ...
https://casereports.bmj.com/content/2016/bcr-2016-216133
Orolingual angioedema (OLA) is a known complication of intravenous alteplase used to treat ischaemic stroke. The incidence may be as high as 5.1%.
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10 Hemi-orolingual angioedema and ACE inhibition ... - Neurology
https://n.neurology.org/content/60/9/1525
Consecutive patients treated with alteplase for stroke from 1996 through 2001 were prospectively followed. After the first case of angioedema, ...
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11 1194: Alteplase (tPA) Induced Angioedema in a Patient with a...
https://journals.lww.com/ccmjournal/Abstract/2013/12001/1194__Alteplase__tPA__Induced_Angioedema_in_a.1146.aspx
Introduction: Alteplase (Activase®) is a recombinant tissue plasminogen activator (tPA) which has been shown to improve outcomes in acute ischemic stroke ...
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12 Icatibant as a Potential Treatment of Life-Threatening ...
https://www.sciencedirect.com/science/article/pii/S1052305717305232
Alteplase-induced angioedema is characteristic of a bradykinin-mediated reaction, with localized laryngeal, mucosal, and upper airway soft tissue swelling, ...
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13 tPA-Associated Angioedema - Emergency Medicine Blog
https://rebelem.com/tpa-associated-angioedema/
This side effect is tPA-associated angioedema. ... Hemi-Orolingual Angioedema and ACE Inhibition After Alteplase Treatment of Stroke.
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14 A Case Report of Unilateral Orolingual Angioedema ... - Cureus
https://www.cureus.com/articles/12486-a-case-report-of-unilateral-orolingual-angioedema-secondary-to-alteplase-administration
Emergency physicians should be aware of adverse drug reactions prior to administering medication. Alteplase, or tissue plasminogen activator ...
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15 Alteplase-Induced Hemi-Orolingual Angioedema
https://www.consultant360.com/photoclinic/alteplase-induced-hemi-orolingual-angioedema
Kim R, Khan Z, Ciminelli M. Alteplase-induced hemi-orolingual angioedema. Consultant. Published online November 10, 2022. doi:10.25270/con.2022/10.000006.
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16 Angioedema after rt-PA infusion led to airway emergency
https://bjan-sba.org/article/10.1016/j.bjane.2021.04.023/pdf/rba-0-AheadOfPrint-60980e5ca95395264609e0f5.pdf
KEYWORDS: Acute ischemic stroke; Angioedema; Fresh frozen plasma; Airway ... inhibition after alteplase treatment of stroke. Neurology.
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17 Stroke Patient Develops Orolingual Angioedema After Taking ...
https://angioedemanews.com/news/stroke-patient-develops-orolingual-angioedema-following-alteplase/
Alteplase, or tissue plasminogen activator (tPA)​, is a thrombolytic drug that works by preventing the formation of blood clots to ensure a ...
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18 Bradykinic angioedema related to alteplase treated successful ...
https://www.atherosclerosis-journal.com/article/S0021-9150(21)01073-X/abstract
Bradykinic angioedema related to alteplase treated successful by frozen fresh plasma ( FFP) : Case report . · Background and Aims: Recombinant tissue plasminogen ...
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19 Orolingual Angioedema After Intravenous Tissue ...
https://jag.journalagent.com/tjn/pdfs/TJN_26_4_346_348%5BA%5D.pdf
Lingual angioedema after alteplase treatment in a patient with acute ischemic stroke. World J Emerg Med. 2015;6:74-76. 4. Rathbun KM.
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20 Gastrointestinal Angioedema as a Side Effect of Alteplase for ...
https://www.jvir.org/article/S1051-0443(20)30343-2/fulltext
This is a case of gastrointestinal angioedema in a patient who received alteplase for acute ischemic stroke. The patient gave written ...
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21 Life–threatening orolingual angioedema during thrombolysis ...
https://link.springer.com/article/10.1007/s00415-005-0789-9
Orolingual angioedema can occur during thrombolysis with alteplase in stroke patients. However, data about its frequency, severity and the ...
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22 Lingual angioedema with macroglossia during the treatment ...
https://www.dovepress.com/lingual-angioedema-with-macroglossia-during-the-treatment-of-acute-isc-peer-reviewed-fulltext-article-IJGM
Abstract: Alteplase (recombinant tissue plasminogen activator) has been used in the treatment of acute ischemic stroke for 10 years. The ...
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23 Hemi Orolingual Angioedema After tPA administration for ...
https://westjem.com/case-report/hemi-orolingual-angioedema-tpa-administration-acute-ischemic-stroke.html
Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med, 2008;359(13):1317-29. group, I.S.T.c., Sanderock P, ...
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24 Bradykinic-Mediated Angioedema Related to Alteplase ...
https://www.itmedicalteam.pl/articles/bradykinicmediated-angioedema-related-to-alteplase-successfully-treated-by-frozen-fresh-plasma-ffp-in-saudi-arabia-a-first-case-re.pdf
Mediated Angioedema Related to Alteplase. Successfully Treated by Frozen Fresh Plasma. (FFP) in Saudi Arabia: A First Case Report.
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25 Orolingual Angioedema with Alteplase Administration for ...
https://www.jem-journal.com/article/S0736-4679(13)00135-2/fulltext
Orolingual Angioedema with Alteplase Administration for Treatment of Acute Ischemic Stroke. Elizabeth M. Gorski, PHARMD, MBA, BCPS.
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26 Isolated Tongue Angioedema after Alteplase Infusion in Acute ...
https://www.ingentaconnect.com/content/ben/cds/2022/00000017/00000001/art00014
Background: Angioedema, like anaphylaxis, has been reported as a rare adverse event of alteplase infusion in acute ischemic stroke.
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27 A SEVERE CASE OF ALTEPLASE-INDUCED ANGIOEDEMA - SHM ...
https://shmabstracts.org/abstract/a-severe-case-of-alteplase-induced-angioedema/
This complication is thought to have no impact on outcome for patients with acute ischemic stroke, but cases of severe angioedema requiring intubation have been ...
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28 Lingual angioedema after alteplase treatment in a patient with ...
https://www.semanticscholar.org/paper/Lingual-angioedema-after-alteplase-treatment-in-a-Bozkurt-Arslan/1d1ba23b34b31452dd4d8d47acc536562538f147
Lingual angioedema may appear as a possible complication in patients who were treated with alteplase and the management of these patients should be very ...
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29 Improving Post Alteplase Documentation of Neurologic ...
https://oregonstrokenetwork.org/doc/Shatzel_M_OSNPoster2019.pdf
Improving Post Alteplase Documentation of Neurologic Assessments, Blood Pressure,. Orolingual Angioedema, and Bleeding. Margaret Shatzel MSPH, RN, SCRN.
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30 Angioedema Post-tPA: Hemorrhage Is Not the Only Risk Factor
https://cdn.mdedge.com/files/s3fs-public/em049050216.pdf
angioedema or any prior similar episodes. ... able, tPA-induced angioedema was shown ... and angioedema during alteplase treatment of acute ischemic stroke.
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31 Orolingual angioedema following intravenous alteplase ...
https://www.jstage.jst.go.jp/article/jstroke/38/3/38_10373/_article
Orolingual angioedema following intravenous alteplase therapy for stroke patients treated with angiotensin converting enzyme (ACE) inhibitor: Case report.
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32 Full article: Select hyperacute complications of ischemic stroke
https://www.tandfonline.com/doi/full/10.1080/14737175.2018.1521723
Select hyperacute complications of ischemic stroke: cerebral edema, hemorrhagic transformation, and orolingual angioedema secondary to intravenous Alteplase.
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33 Activase® (alteplase) | Treatment for Acute Ischemic Stroke (AIS)
https://www.activase.com/
Angioedema has been observed during and up to 2 hours after Activase infusion in patients treated for acute ischemic stroke and acute myocardial infarction.
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34 Icatibant for the treatment of orolingual angioedema following ...
https://www.ajemjournal.com/article/S0735-6757(18)30209-2/abstract
Barber P.A.; Takahashi J. et al. Anaphylactoid reactions and angioedema during alteplase treatment of acute ischemic stroke. CMAJ. 2000; ...
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35 Alteplase Induced Angioedema: A Case of a Life-threatening ...
https://scholarlyworks.beaumont.org/internal_medicine_confabstract/15/
Orolingual angioedema occurs in one- to five-percent of patients treated with alteplase. When it does occur, it is usually mild and ...
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36 ACTIVASE (alteplase) for injection - Accessdata.fda.gov
https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/103172s5203lbl.pdf
If angioedema develops, discontinue Activase. (5.2). • Acute Myocardial Infarction (AMI) to reduce mortality and incidence of.
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37 PowerPoint Presentation
https://cdn.ymaws.com/www.easternstates.org/resource/resmgr/2018_conference/Management_of_Orolingual_An.pptx
Management of Orolingual Angioedema Post-Alteplase Treatment in Stroke Patients. Oumaima Sahbani, PharmD. PGY1 Pharmacy Resident.
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38 InpharmD™
https://inpharmd.com/is-there-any-data-on-alteplase-causing-angioedema
Is there any data on alteplase causing angioedema? Comment by InpharmD Researcher. Orolingual angioedema (OA) is identified to be a rare but potentially serious ...
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39 Table 1: Management of Orolingual Angioedema Associated ...
https://www.acep.org/globalassets/sites/acep/media/equal-documents/stroke-documents/angioedematable-1.pdf
Table 1: Management of Orolingual Angioedema Associated with IV Alteplase Administration for. Acute Ischemic Stroke (Class IIb; Level of Evidence C-EO)1.
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40 Angioedema - EMCrit Project
https://emcrit.org/ibcc/angioedema/
Without medical therapy, bradykinin-induced angioedema may take days to resolve. Allergy-type therapies (steroid, antihistamine, epinephrine) ...
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41 Facial and oropharyngeal angioedema after tenecteplase ...
https://www.ljmsonline.com/article.asp?issn=2588-9044;year=2020;volume=4;issue=4;spage=201;epage=203;aulast=Alzwi
They are more commonly reported during or after the treatment of acute ischemic stroke with alteplase compared to myocardial infarction (MI).
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42 Lingual angioedema after alteplase treatment in a patient with ...
https://wikidata.org/wiki/Q41390843
Lingual angioedema after alteplase treatment in a patient with acute ischemic stroke. scientific article published on January 2015. Spanish.
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43 Urticaria, angioedema, and type I hypersensitivity reactions ...
https://apjai-journal.org/wp-content/uploads/2019/10/AP-050619-0574.pdf
Methods: This was a retrospective study in which cases of suspected adverse drug reactions from the use of streptoki- nase, alteplase, and tenecteplase were ...
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44 Hemi-orolingual angioedema and ACE inhibition after ...
https://ora.ox.ac.uk/objects/uuid:df86dfb7-5692-4838-8027-f29a2108e3c8
Hemi-orolingual angioedema and ACE inhibition after alteplase treatment of stroke. Abstract: One hundred seventy-six consecutive patients treated with IV ...
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45 Anaphylactoid reactions and angioedema during alteplase ...
https://www.researchgate.net/publication/12504897_Anaphylactoid_reactions_and_angioedema_during_alteplase_treatment_of_acute_ischemic_stroke
Among 105 patients given recombinant tissue plasminogen activator (rt-PA, alteplase) intravenously for acute stroke, 2 (1.9%) had lingual angioedema, ...
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46 Anaphylactoid reactions and angioedema during ... - ProQuest
https://search.proquest.com/openview/2d10e5e70e4561c449d438a21f9e96b3/1?pq-origsite=gscholar&cbl=41339
(f.3,4) Angioedema has been reported in association with alteplase treatment of myocardial ischemia(f.5,6) and deep vein thrombosis,(f.7,8) but very rarely in ...
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47 Raising Awareness of Orolingual Angioedema as a ...
https://www.karger.com/Article/Pdf/201558
venous alteplase application, often contralateral to the ischemic lesion. ... angioedema and ACE inhibition after alteplase treatment of stroke.
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48 An Unexpected -- and Potentially Deadly -- tPA Interaction
https://www.medpagetoday.com/casestudies/cardiology/90993
In response to her orolingual angioedema, clinicians stop the alteplase and perform emergency intubation to protect her airway.
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49 Early Acute Ischemic Stroke Management for Pharmacists
https://journals.sagepub.com/doi/abs/10.1177/0018578718791504
Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke (ECASS 3). ... Anaphylactoid reactions and angioedema during alteplase treatment of ...
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50 Analysis of related factors of orolingual angioedema after rt ...
https://www.europeanreview.org/wp/wp-content/uploads/1478-1484.pdf
intravenous application of alteplase (rt-PA) in patients with acute ischemic stroke. The pur- pose of this work is to investigate the related.
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51 A First Case Report and Literature Review | Abstract
https://www.jneuro.com/abstract/bradykinicmediated-angioedema-related-to-alteplase-successfully-treated-by-frozen-fresh-plasma-ffp-in-saudi-arabia-a-first-case-report-and-literature-review-37613.html
Bradykinic-Mediated Angioedema Related to Alteplase Successfully Treated by Frozen Fresh Plasma (FFP) in Saudi Arabia: A First Case Report and Literature ...
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52 Angioedema in the neurointerventional suite
https://www.or.org/bibliography/PDF/1124220263/Sonny-2015.pdf
Engelter et al [5] retrospectively looked at 121 patients who received alteplase for acute ischemic stroke and found 2. (1.7%) patients with angioedema.
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53 Life-threatening complications with tPA – what emergency ...
http://www.emdocs.net/life-threatening-complications-with-tpa-what-emergency-physicians-should-know/
Angioedema is estimated to occur in 1.3 – 5.1% of stroke patients ... Hemi-orolingual angioedema and ACE inhibition after alteplase ...
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54 Anaphylactoid reactions and angioedema during alteplase ...
https://www.nlc-bnc.ca/eppp-archive/100/201/300/cdn_medical_association/cmaj/vol-162/issue-9/1281.htm
Among 105 patients given recombinant tissue plasminogen activator (rt-PA, alteplase) intravenously for acute stroke, 2 (1.9%) had lingual angioedema, which ...
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55 Angioedema Risk Associated With Central Vascular Access ...
https://nursing.ceconnection.com/ovidfiles/00129804-201909000-00006.pdf;jsessionid=DB68118047CB0287BA00253931CA061C
(FDA) in 2001, low-dose alteplase, marketed as. Cathflo Activase (Genentech, San Francisco, CA), is the standard of care for the restoration of throm-.
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56 Orolingual angioedema during thrombolysis in acute ischemic ...
http://wjem.com.cn/EN/article/downloadArticleFile.do?attachType=PDF&id=668
alteplase administration is becoming more common— orolingual angioedema (OA).[4-6] OA is acute swelling of the tongue, lips or face and may be ...
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57 Hemi-orolingual angioedema due to IV Alteplase ...
https://pesquisa.bvsalud.org/global-literature-on-novel-coronavirus-2019-ncov/resource/pt/covidwho-1307800
the incidence of angioedema secondary to Alteplase administration increases with the use of ACE-I. In the Covid-19 Pandemic period, it is important to ...
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58 Hemi Orolingual Angioedema after tPA ... - eScholarship.org
https://escholarship.org/content/qt40q9665x/qt40q9665x_noSplash_e7cc06b43bf98ee5818616b2ded63363.pdf
orolingual angioedema during thrombolysis in acute ischemic stroke. They reported two cases (1.7%) of 120 patients treated with alteplase ...
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59 HIGHLIGHTS OF PRESCRIBING INFORMATION These ...
https://www.gene.com/download/pdf/activase_prescribing.pdf
Activase (alteplase) for injection, for intravenous use ... If signs of hypersensitivity occur, e.g. anaphylactoid reaction or angioedema.
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60 ischemic-stroke-intial-24-hours-post-thrombolysis-order-set.pdf
https://physicians.northernhealth.ca/sites/physicians/files/news/documents/2020/ischemic-stroke-intial-24-hours-post-thrombolysis-order-set.pdf
Angioedema has been reported in 1.3% (8/596; 95% CI 0.6 to 2.6%) of patients treated with IV alteplase (t͈PA) therapy for acute stroke.
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61 Lingual angioedema after alteplase treatment in a patient with ...
http://apbs.mersin.edu.tr/files/akose/Publications_002.pdf
He was diagnosed as having acute ischemic stroke, and alteplase infusion was given two ... KEY WORDS: Angioedema; Alteplase; Ischemic stroke.
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62 The Role of the Plasminogen Activation System in Angioedema
https://www.mdpi.com/2077-0383/10/3/518
Different forms of angioedema are linked to uncontrolled activation of coagulation ... angioedema and ACE inhibition after alteplase treatment of stroke.
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63 https://www.nursingcenter.com/ce_articleprint?an=0...
https://www.nursingcenter.com/ce_articleprint?an=01261775-201907000-00004
› ce_articleprint
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64 t-PA angioedema
https://www.aaaai.org/allergist-resources/ask-the-expert/answers/old-ask-the-experts/tpa
"Anaphylactic reactions with urticaria and hypotension and deaths have been reported with the use of TPA/Alteplase (Zarar A et al Am J Emerg ...
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65 Acute Ischemic Stroke - ACCP
https://www.accp.com/docs/bookstore/psap/p2020b1_sample.pdf
Design a patient-specific pharmacotherapeutic regimen to treat adverse events associated with intravenous alteplase, including hemorrhage and angioedema. 2.
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66 Alteplase: Uses, Interactions, Mechanism of Action - DrugBank
https://go.drugbank.com/drugs/DB00009
Alteplase is a recombinant form of human tissue plasminogen ... Alogliptin, The risk or severity of angioedema can be increased when ...
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67 Advances in Urticaria Research and Treatment: 2012 Edition: ...
https://books.google.com/books?id=3wzSUByHwX0C&pg=PA3&lpg=PA3&dq=alteplase+angioedema&source=bl&ots=8e5vDzrpzP&sig=ACfU3U2tM56l1UuYHzT1SpITGUI8jpxD2Q&hl=en&sa=X&ved=2ahUKEwjhrbODoN77AhXTr5UCHVRhBhcQ6AF6BQiwAhAD
Department of Internal Medicine, Landau: Lingual angioedema with macroglossia during the treatment of acute ischemic stroke with alteplase A new study, ...
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68 Hemi-orolingual angioedema and ACE ... - QUT ePrints
https://eprints.qut.edu.au/85222/
Hemi-orolingual angioedema and ACE inhibition after alteplase treatment of stroke. Hill, M. D., Lye, T., Moss, H., Barber, P. A., Demchuk, ...
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69 Related factors with orolingual angioedema after intravenous ...
https://search.ebscohost.com/login.aspx?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=15901874&AN=154457517&h=m0r1DN5oRqMzx8XFgq0BsUHJSReHXqy8GkxzGVwmNX9MICBeIv66AewTUXfnVUCUZpypNbbyfwXcjlWHky2ung%3D%3D&crl=f
alteplase in acute ischemic stroke: results from a single-center ... Orolingual angioedema after intravenous alteplase is a known adverse.
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70 Angioedema Secondary to IV Tissue Plasminogen Activator ...
https://go.gale.com/ps/i.do?id=GALE%7CA587143061&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=20906420&p=HRCA&sw=w
Angioedema secondary to tPA administration is a rare side effect with an estimated incidence of 0.02% in patients being treated with alteplase for acute MI ...
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71 Managing Complications of Acute Stroke Therapy
https://emottawablog.com/2022/09/managing-complications-of-acute-stroke-therapy/?utm_source=rss&utm_medium=rss&utm_campaign=managing-complications-of-acute-stroke-therapy
Orolingual Angioedema. The incidence of orolingual angioedema after Alteplase (tPA) administration in acute ischemic stroke is between 1.3-5.1%.
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72 Alteplase Administration for Stroke - Texas Health Resources
http://lmscs.texashealth.org/courses/catalog/Activase(alteplase).pdf
other, For Alteplase/Activase induced Angioedema. 10 mg, SLOW IV PUSH, ONCE AS NEEDED For 1 Doses hypertension, For blood pressure above goal.
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73 Orolingual angioedema treated with Icatibant post ...
https://www.jocn-journal.com/article/S0967-5868(17)31843-X/fulltext
Asymmetric oro-facial angioedema following alteplase for acute ischaemic stroke. Teddy Y. Wu. *. , Diana Y. Wei, Yvette Baker, Brendan Sharkey, ...
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74 Emerging concepts in the diagnosis and treatment of patients ...
https://intjem.biomedcentral.com/articles/10.1186/1865-1380-5-39
Angioedema is a sudden, transient swelling of well-demarcated areas of ... to changes in prostaglandin synthesis [5, 11]—and alteplase [22].
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75 Updates in Stroke - UT Southwestern |
https://cme.utsouthwestern.edu/sites/default/files/course/2022-04/1315_JONES_Updates%20in%20Stroke%202022%20%281%29.pdf
▫Adverse reactions: Bleeding, Angioedema, Anaphylaxis, Fever. Thrombolytic Therapy: Alteplase. 14. Reed M, Kerndt CC, Nicolas D. Alteplase.
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76 Angioedema, An Issue of Immunology and Allergy Clinics of ...
https://books.google.com/books?id=Si4tDwAAQBAJ&pg=PA493&lpg=PA493&dq=alteplase+angioedema&source=bl&ots=GDbeGE7cx1&sig=ACfU3U3aTUypCulUSQkuddsr_H0oVaRUbw&hl=en&sa=X&ved=2ahUKEwjhrbODoN77AhXTr5UCHVRhBhcQ6AF6BQizAhAD
Orolingual angioedema after alteplase therapy of acute ischaemic stroke: incidence and risk of prior angiotensin-converting enzyme inhibitor use.
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77 stroke-drip-and-ship-protocol.pdf - Essentia Health
https://www.essentiahealth.org/app/files/public/253/stroke-drip-and-ship-protocol.pdf
If neuro status decline, STOP alteplase infusion and repeat. Head CT. • Bleeding Risk - monitor and assess frequently. • Angioedema – if present in ...
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78 Is angioedema secondary to IV tPA considered ... - theMednet
https://www.themednet.org/is-angioedema-secondary-to-iv-tpa-considered-an-absolute-contraindication-for-tpa-in-future
In short, no. In general, the only absolute contraindications to alteplase and other forms of tPA are active bleeding or situations that could result in ...
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79 Activase, TPA (alteplase) dosing, indications, interactions ...
https://reference.medscape.com/drug/activase-tpa-alteplase-342287
Medscape - Thrombolysis dosing for Activase, TPA (alteplase), ... e.g. anaphylactoid reaction or angioedema develops, discontinue therapy and promptly ...
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80 Anaphylactoid reactions and angioedema during ... - Yumpu
https://www.yumpu.com/en/document/view/22011102/anaphylactoid-reactions-and-angioedema-during-alteplase-
angioedema during alteplase. treatment of acute ischemic stroke. Research. Recherche. Michael D. Hill, Philip A. Barber, Jennifer Takahashi,.
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81 Revised 08.2019 EMS Interfacility Ground Transport Protocol ...
https://dph.georgia.gov/document/document/ems-interfacility-ground-transport-protocol-patients/download
Total Alteplase infusion time should be 60 minutes ... ***STOP Alteplase if the patient develops the ... **Withhold Epi unless angioedema is causing.
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82 Regional Stroke Protocol - St. Luke's
https://www.slhduluth.com/documents/Duluth-Regional-Stroke_4.21.pdf
Bleeding Risk - monitor and assess frequently. • Angioedema – if present in tongue/oropharynx, STOP alteplase infusion. See Medication Considerations.
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83 Textbook of Neuroanesthesia and Neurocritical Care: Volume ...
https://books.google.com/books?id=1waWDwAAQBAJ&pg=PA119&lpg=PA119&dq=alteplase+angioedema&source=bl&ots=1L4t3kyxqm&sig=ACfU3U2hK0_iC6K2MYvrwyHD2lBHLxd3dg&hl=en&sa=X&ved=2ahUKEwjhrbODoN77AhXTr5UCHVRhBhcQ6AF6BQi7AhAD
Alteplase is not without side effects and complications. Most dangerous of them are intracranial hemorrhage and angioedema with following airway obstruction ...
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84 Bradykinin: Inflammatory Product of the Coagulation System
https://d-nb.info/1098606736/34
in hereditary angioedema (HAE) and the central role that the ... (2015) Lingual angioedema after alteplase treatment in a patient.
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85 Side Effects of Drugs Annual - Page 355 - Google Books Result
https://books.google.com/books?id=dXXhDwAAQBAJ&pg=PA355&lpg=PA355&dq=alteplase+angioedema&source=bl&ots=vbdWWMrmrJ&sig=ACfU3U2-zYc0XWZeCjn58MaZPUL4JtPBEg&hl=en&sa=X&ved=2ahUKEwjhrbODoN77AhXTr5UCHVRhBhcQ6AF6BQjBAhAD
This case demonstrated a rare adverse effect of orolingual angioedema with alteplase administration, which may have additive effects from losartan due to ...
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86 Cumulated Index Medicus - Page 2609 - Google Books Result
https://books.google.com/books?id=PFVW-mIQuzkC&pg=PA2609&lpg=PA2609&dq=alteplase+angioedema&source=bl&ots=bs_MabQKhn&sig=ACfU3U0pybfZmCSc0us1X5axo4b3m1IhhQ&hl=en&sa=X&ved=2ahUKEwjhrbODoN77AhXTr5UCHVRhBhcQ6AF6BQi6AhAD
Penile angioedema possibly related to lisinopril ( letter ) Asphyxiation by ... angiomyolipoma in Anaphylactoid reactions and angioedema during alteplase ...
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87 Meyler's Side Effects of Drugs: The International ...
https://books.google.com/books?id=NOKoBAAAQBAJ&pg=RA4-PA919&lpg=RA4-PA919&dq=alteplase+angioedema&source=bl&ots=v50dEND5L8&sig=ACfU3U0BF2uvjwei6IJlzoFwvb1guTPrtQ&hl=en&sa=X&ved=2ahUKEwjhrbODoN77AhXTr5UCHVRhBhcQ6AF6BQjAAhAD
There have been three reports of anaphylactoid reactions, mostly orolingual angioedema, after therapy of acute ischemic stroke with alteplase.
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88 Learn More About Target: Stroke | American Heart Association
https://www.heart.org/en/professional/quality-improvement/target-stroke/learn-more-about-target-stroke
Alteplase, the current standard of care for stroke, ... trials focused on ischemic stroke have directly compared alteplase and tenecteplase, ...
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89 Alteplase reconstitution and administration - YouTube
https://www.youtube.com/watch?v=GwpUJ-X_GFQ
Oct 10, 2018
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90 Human medicine European public assessment report (EPAR)
https://www.ema.europa.eu/en/medicines
› medicines
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91 Actilyse® Cathflo® administration videos - Boehringer Ingelheim
https://pro.boehringer-ingelheim.com/uk/resources/catheter-related-thrombotic-occlusion-healthcare-professional-resource/actilyse-cathflo-administration-videos
Learn more about the administration process for ACTILYSE Cathflo (alteplase). Intended for UK healthcare professionals only.
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92 Alteplase (tPA, Activase) Nursing Considerations
https://nursing.com/lesson/drug-alteplase-tpa-activase
Generic Name. Alteplase. Trade Name. tPA, Activase. Indication. MI, acute ischemic stroke, occluded central lines. Action. Converts plasminogen to plasmin ...
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