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1 Inhibition of MHC Class I Is a Virulence Factor in Herpes ...
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.0010007
Major histocompatibility complex (MHC) class I molecules are a particularly attractive target for immune evasion by viruses, because decreasing ...
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2 A cytosolic herpes simplex virus protein inhibits antigen ...
https://www.cell.com/fulltext/0092-8674(94)90215-1
Herpes simplex virus (HSV) infection of human fibroblasts rapidly renders the cells resistant to lysis by HSV-specific CD8+ cytotoxic T lymphocytes (CTLs), ...
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3 Herpes Simplex Virus Type 1 Targets the MHC Class II ...
https://www.jimmunol.org/content/jimmunol/171/6/3075.full.pdf
T cell help. HSV-1 infection targets the molecular coplayers of MHC class II processing, HLA-DR (DR), HLA-DM (DM), and invariant chain (Ii).
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4 Herpes simplex virus-1 evasion of CD8 + T cell accumulation ...
https://www.jci.org/articles/view/92931
Therefore, the MHC-I antigen presentation pathway appears to be a prime target for attack by many viruses to evade CD8+ T cells. In fact, HSV-1 ...
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5 Inhibition of MHC class I is a virulence factor in herpes simplex ...
https://escholarship.org/uc/item/2s44x0p0
Herpes simplex virus (HSV) has a number of genes devoted to immune evasion. One such gene, ICP47, binds to the transporter associated with antigen ...
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6 Evasion of the Cell-Mediated Immune Response by ... - MDPI
https://www.mdpi.com/1999-4915/12/12/1354/htm
Herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV) ... At least three HSV proteins inhibit the MHC class I antigen presentation ...
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7 Viral immune evasion: Lessons in MHC class I antigen ...
https://www.sciencedirect.com/science/article/abs/pii/S1044532315000184
HSV-1. herpes simplex virus-1. LANA-1. latency-associated nuclear antigen-1. KSHV. Kaposi's sarcoma-associated herpesvirus. MHC I/II.
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8 Molecular Basis for the Recognition of Herpes Simplex Virus ...
https://www.frontiersin.org/articles/10.3389/fimmu.2018.00183/full
Thus, importance of downregulating MHC I for clearance of HSV1 infection by NK cells in vivo remains unresolved and awaits better models to ...
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9 Molecular mechanisms of human herpes viruses inferring with ...
https://jitc.bmj.com/content/8/2/e000841
The human herpes virus (HHV) 1 (herpes simplex virus 1, HSV-1) produces the protein ICP47 that blocks the peptide loading on the MHC class I HC by direct ...
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10 Equine herpesvirus and the major histocompatibility complex ...
https://www.vet.cornell.edu/departments-centers-and-institutes/baker-institute/research/equine-herpesvirus-and-major-histocompatibility-complex-mhc
The goal of this project is to determine the importance of MHC class I molecules as cell-surface receptors for entry of equine herpes virus type 1 (EHV-1) ...
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11 Inhibition of Major Histocompatibility Complex Class I Antigen ...
https://journals.asm.org/doi/10.1128/JVI.72.6.5076-5084.1998
ABSTRACT Herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) express an ... Construction of recombinant HSV-1 able to express murine MHC class I proteins ...
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12 H-2Kb/HSV-1 glycoprotein B (SSIEFARL) MHC Tetramer
https://www.creativebiolabs.net/H-2Kb-HSV-1-gB-498-505-MHC-Tetramer-59394.htm
H-2Kb/HSV-1 glycoprotein B (SSIEFARL) MHC Tetramer. Suitable for use in FCM in Immunology research. Belongs to the Mouse Class I family.
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13 The Active Site of ICP47, a Herpes Simplex Virus–encoded ...
https://rupress.org/jem/article/185/9/1565/25426/The-Active-Site-of-ICP47-a-Herpes-Simplex-Virus
As a consequence, empty major histocompatibility complex (MHC) class I molecules are retained in the endoplasmic reticulum and recognition of HSV-infected cells ...
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14 Projects | Johnson Lab | OHSU
https://www.ohsu.edu/school-of-medicine/johnson-lab/projects
Our lab focuses on two human herpesviruses: herpes simplex virus (HSV) and human ... of MHC class I or II proteins by viral proteins (Hegde et al.
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15 Bovine Herpesvirus 1 Downregulates the Expression of ...
https://www.liebertpub.com/doi/10.1089/vim.1997.10.21
Bovine Herpesvirus 1 Downregulates the Expression of Bovine MHC Class I Molecules · CHANDRASEKARAN NATARAJ · SUSANNE EIDMANN · MANGALA J. HARIHARAN ...
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16 Autophagy enhances the presentation of endogenous viral ...
https://www.nature.com/articles/ni.1720
Here we showed that although macrophages infected with herpes simplex virus ... the presentation of HSV-1 antigens on MHC class I molecules.
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17 Immunoevasin - Wikipedia
https://en.wikipedia.org/wiki/Immunoevasin
Immunoevasins are proteins expressed by some viruses that enable the virus to evade immune recognition by interfering with MHC I complexes in the infected cell, ... 2.1 Herpes simplex virus (HSV-1 and HSV-2); 2.2 Human cytomegalovirus ...
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18 Novel transcription regulatory sequences and factors of the ...
https://virologyj.biomedcentral.com/articles/10.1186/s12985-020-01365-3
Herpes simplex virus (HSV) can cause encephalitis. ... and this keeps the cell surface MHC-I-antigen expression and allows to enhance ...
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19 Exploiting human herpesvirus immune evasion for therapeutic ...
https://onlinelibrary.wiley.com/doi/pdf/10.1038/icb.2010.129
herpesvirus obstruction of MHC class I-restricted antigen ... families: the α-herpesviruses herpes simplexvirus types 1 and 2 (HSV-.
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20 Herpes simplex virus type 1 encephalitis - UpToDate
https://www.uptodate.com/contents/herpes-simplex-virus-type-1-encephalitis
Herpes simplex virus type 1 (HSV-1) encephalitis is the most common cause ... Major histocompatibility complex (MHC) structure and function ...
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21 "MHC Class I Expression in Murine Fibroblast and ...
https://corescholar.libraries.wright.edu/etd_all/596/
The hypothesis of this study is: HSV-1 infection of murine fibroblasts and keratinocytes inhibits expression of MHC class I molecules during first 24 hours ...
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22 Inhibition of host MHC class I molecule presentation by virus
https://viralzone.expasy.org/819
US2 and US11 of HCMV and mK3 form mouse herpesvirus 68 target human MHC class I molecules for degradation through the ERAD pathway.
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23 Association of Major Histocompatibility Complex Determinants ...
https://academic.oup.com/jid/article/179/5/1077/800658
The clinical spectrum of herpes simplex virus (HSV) infections, ranging from ... Coexpression of HSV peptides in the context of MHC class I and class II ...
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24 Structure of the transporter associated with antigen processing ...
https://elifesciences.org/articles/21829
Herpes simplex virus evades the immune response by inhibiting the TAP ... The same TAP transporter provides peptides for all six MHC-I ...
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25 Receptor Modulation in Viral replication: HIV, HSV, HHV-8 ...
https://link.springer.com/chapter/10.1007/3-540-26764-6_7
HIV, HPV, HSV, and HHV-8 subvert the class I major histocompatibility complex (MHC-I) antigen presentation pathway, thereby evading the cellular immune ...
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26 T Cell Responses to Herpes Simplex Viruses in Humans - jstor
https://www.jstor.org/stable/4456174
measles virus [14, 15], varicella zoster virus (VZV) [16], influenza virus [17], and Mycobacterium species [18, 19]. MHC Restriction and Frequency of.
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27 KEGG Herpes simplex virus 1 infection - Homo sapiens (human)
https://www.kegg.jp/kegg-bin/show_pathway?hsa05168
N00566 HSV UL36USP to RIG-I-like receptor signaling pathway ... N00581 HSV ICP47 to antigen processing and presentation by MHC class I molecules
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28 Comparing Effects of BK Virus Agnoprotein and Herpes ...
https://www.hindawi.com/journals/jir/2013/626823/
Unlike the HSV-1 ICP47, BKV agnoprotein does not contribute to viral immune ... Virus Agnoprotein and Herpes Simplex-1 ICP47 on MHC-I and MHC-II Expression.
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29 Ubiquitylation of MHC class I by the K3 viral protein signals ...
https://www.embopress.org/doi/10.1093/emboj/21.10.2418
The Kaposi's sarcoma-associated herpes virus gene product K3 (KK3) subverts the MHC class I antigen presentation pathway by downregulating MHC class I from ...
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30 Crystal structures of glycoprotein D of equine ... - bioRxiv
https://www.biorxiv.org/content/10.1101/2022.06.10.495596v1.full
Equine herpesvirus type 1 (EHV-1) and EHV-4 use equine major histocompatibility complex class I (MHC-I) as an entry receptor, however, no ...
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31 Immunity to and Prevention of Herpes Zoster
https://books.google.com/books?id=BEdJhaVF0oUC&pg=PA100&lpg=PA100&dq=herpes+mhc&source=bl&ots=0dsQ2XX5sE&sig=ACfU3U0huT0gcQcfacrqKJB3ZqFy7dHJUg&hl=en&sa=X&ved=2ahUKEwiQhqygq977AhXvHjQIHfJLCoAQ6AF6BAgpEAM
these observations , immunomodulatory mechanisms that limit the initial presentation of VZV peptides by MHC class I or class II pathways are likely to have ...
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32 COVID-19: Attacks Immune Cells and Interferences with ...
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/6108fd830321148575b994b9/original/covid-19-attacks-immune-cells-and-interferences-with-antigen-presentation-through-mhc-like-decoy-system.pdf
Mutations in the MHC-like region of the viral proteins such as S ... About half of the identified genes in cytomegalovirus(23) and beta herpes.
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33 KEGG T01001: 3135
https://www.genome.jp/entry/hsa:3135
nt06166 Human papillomavirus (HPV) nt06167 Human cytomegalovirus (HCMV) nt06168 Herpes simplex virus 1 (HSV-1) nt06229 MHC presentation. Element ...
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34 Downregulation of host cell MHC–I surface ... - IOVS
https://iovs.arvojournals.org/article.aspx?articleid=2407224
Abstract: : Purpose: Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that can reactivate and cause ophthalmic zoster, potentially leading to ...
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35 Immune evasion strategies of the herpesviruses - CORE
https://core.ac.uk/download/pdf/81932968.pdf
the closely related herpes simplex viruses (HSV) types 1 and 2, and human cytomegalovirus ... that ICP47 is the only HSV protein affecting MHC class I.
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36 Vaccine Formulation and Optimization for Human Herpes ...
https://pubs.acs.org/doi/abs/10.1021/acsptsci.0c00139
Molecular dynamics simulation analyses revealed the strong binding of the vaccine with MHC receptors (MHC-1 and MHC-2) and the virus ...
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37 latency and reactivation – viral strategies and host response
https://www.tandfonline.com/doi/full/10.3402/jom.v5i0.22766
The five that cause the most health concerns are: herpes simplex virus ... of viral antigens via the major histocompatibility complex (MHC) of infected ...
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38 Fundamental Immunology
https://lvts.fr/Pages_html/Encyclopedies/FundamentalImmunology/ramiCOMMAND=applyStylesheet(interface.xsl,[email protected])&p_userid=pau.html
Inhibition of antigen presentation through the class I MHC pathway. Virus. Viral product(s) ... Inhibits class I MHC synthesis. HCMV. US6. Inhibits TAP. HSV.
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39 Insight into the Mechanism of Human Herpesvirus 7 U21 ...
https://www.jbc.org/article/S0021-9258(20)46850-4/fulltext
The U21 open reading frame from human herpesvirus-7 encodes a membrane protein that associates with and redirects class I MHC molecules to ...
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40 Causes of Lupus
https://www.hopkinslupus.org/lupus-info/lupus/
The strength of the association of MHC II genes with lupus varies by ... herpes zoster virus (the virus that causes shingles), and cytomegalovirus have also ...
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41 1RJY: Mhc Class I Natural Mutant H-2Kbm8 Heavy Chain ...
https://www.rcsb.org/structure/1RJY
This polymorphism determines resistance to lethal herpes simplex virus (HSV-1) infection by modulating T cell responses to the immunodominant glycoprotein B(498 ...
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42 mHC class I immune evasion strategies of herpes viruses
https://www.researchgate.net/figure/mHC-class-I-immune-evasion-strategies-of-herpes-viruses_tbl4_49676095
Download Table | mHC class I immune evasion strategies of herpes viruses from publication: Herpesvirus vaccines: Challenges and future prospects | Human ...
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43 Manipulation of the MHC Class II Antigen Presentation Pathway
https://research.birmingham.ac.uk/files/7110824/viruses_04_01335.pdf
by J Zuo · Cited by 38 —
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44 Herpes Simplex Viruses - Google Books Result
https://books.google.com/books?id=I-5HDwAAQBAJ&pg=PT73&lpg=PT73&dq=herpes+mhc&source=bl&ots=F6cVNPFEgw&sig=ACfU3U0ftUXeIAU_JqPZx8CZ_fTtlxVBMA&hl=en&sa=X&ved=2ahUKEwiQhqygq977AhXvHjQIHfJLCoAQ6AF6BAgoEAM
HSV evades cytotoxic T-lymphocyte recognition by interfering with the Major Histocompatibility Complex class I antigen presentation pathway. MHC class I is ...
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45 Conquering the Host: Determinants of Pathogenesis Learned ...
https://www.annualreviews.org/doi/10.1146/annurev-virology-011921-082615
The MHV68 genome (3) is colinear with Kaposi sarcoma herpesvirus (KSHV, HHV-8) and ... (b) MHC II−/− mice that are CD4+ T cell deficient succumb within 4 ...
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46 MHC-II gene and its association with disease ... - ProQuest
https://search.proquest.com/openview/c589b749cc0cfce556afb75384c54b0e/1?pq-origsite=gscholar&cbl=2046424
Koi herpes virus (KHV) disease is one of the main problems in common carp (Cyprinus carpió) culture in Indonesia. In teleost fish, Major Histocompatibility ...
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47 Analysis of ALS-related proteins during herpes simplex virus-2 ...
https://d-nb.info/1225170370/34
Regarding that, “MHC-II hot-spots” would be. HSV-2 attempts of reactivation in infected neurons de- tected by microglia. These attempts are not unusual in. HSV ...
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48 THE EFFECT OF CRUDE PROTEIN HALIMEDA SP. ON ...
https://jfmr.ub.ac.id/index.php/jfmr/article/view/14
ON CYPRINUS CARPIO INFECTED KOI HERPES VIRUS ON EXPRESSION OF ... is the crude protein of Halimeda sp. able to activate the MHC class I and ...
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49 Herpes Simplex Virus (HSV), Culture From Neonates, Varies
https://mhc.testcatalog.org/show/VHSV
An aid in the diagnosis of congenital herpes simplex virus (HSV) infection in patients younger than 35 days old through the recovery of HSV using viral ...
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50 MHC-II gene and its association with disease ... - CAB Direct
https://www.cabdirect.org/cabdirect/abstract/20193004666
Koi herpes virus (KHV) disease is one of the main problems in common carp (Cyprinus carpio) culture in Indonesia. In teleost fish, Major Histocompatibility ...
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51 how to fully cure for hsv in homeopathy - naokomarketing.me
https://naokomarketing.me/how-to-fully-cure-for-hsv-in-homeopathy.html
हर्पीज का इलाज, herpes zoster homeopathic treatment, by dr pradeep pandey, mhc (Martand Homeopathic Clinic),#homeopathictreatment ...
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52 troy university std rate - Desentupidora Khalu
https://desentupidorakhalu.com.br/44resr/viewtopic.php?page=troy-university-std-rate
Herpes is a viral infection cause by the Herpes simplex virus, ... started on natural alternative PARKINSONS DISEASE treatment from M.H.C. In 1806 President ...
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53 reversing hsv2
https://giantsofeden.it/reversing-hsv2.html
Current antiviral medications to treat herpes include the followingThe HSV 2 ... partially reverses the MHC class I Herpes simplex virus type 1 (HSV-1) is a ...
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54 CATCH Miami to open at the James Royal Palm this January
https://www.miamiherald.com/miami-com/restaurants/article225676230.html
› article225676230
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55 Herpes Group (Cytomegalovirus, Herpes simplex, Varicella ...
https://www.meddean.luc.edu/lumen/meded/orfpath/herpes.htm
HERPES GROUP. CYTOMEGALOVIRUS (CMV) HEPATITIS. The infection with this virus is very common but, in healthy people does not produce disease.
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56 Merck to Present Data From Its Hematology Portfolio and ...
https://www.businesswire.com/news/home/20221201005292/en/Merck-to-Present-Data-From-Its-Hematology-Portfolio-and-Promising-Pipeline-at-the-64th-American-Society-of-Hematology-ASH-Annual-Meeting
... major histocompatibility complex (MHC) class II molecules. ... pneumonitis, pyrexia, dyspnea, GVHD, and herpes zoster.
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57 dr molemen herbal medicine reviews
https://romentinesecerano.it/dr-molemen-herbal-medicine-reviews.html
Emergency department presentations due to herpes zoster have also ... my Genital and Herpes Oral Treatment with Natural Dr Molemen's healing medicine, ...
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59 The Lancet - Volume 1 - Page xix - Google Books Result
https://books.google.com/books?id=zLY1AQAAMAAJ&pg=PR19&lpg=PR19&dq=herpes+mhc&source=bl&ots=EMNi-_b5wd&sig=ACfU3U1inFvV5Kx_VCjl_mp6PzAo4C6-jA&hl=en&sa=X&ved=2ahUKEwiQhqygq977AhXvHjQIHfJLCoAQ6AF6BAgnEAM
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60 Chemist and Druggist: The Newsweekly for Pharmacy
https://books.google.com/books?id=TxeIX7FU1G4C&pg=RA12-PR6&lpg=RA12-PR6&dq=herpes+mhc&source=bl&ots=2RIfNMTrCu&sig=ACfU3U1ltG3e_kRw2ljZS03RFB3Nz7xcGg&hl=en&sa=X&ved=2ahUKEwiQhqygq977AhXvHjQIHfJLCoAQ6AF6BAgqEAM
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62 Sammlung klinischer Vorträge: Innere Medizin
https://books.google.com/books?id=JVM5AQAAMAAJ&pg=PA632&lpg=PA632&dq=herpes+mhc&source=bl&ots=KhVELhBwL0&sig=ACfU3U2d-x4mlS8b4oYumCrYNhLhTsDXVA&hl=en&sa=X&ved=2ahUKEwiQhqygq977AhXvHjQIHfJLCoAQ6AF6BAgmEAM
M. H. C. , 31 Jahr alt . 24. ... Schanker 6 monatliche Merkurbehandlung keine Sekundärerscheinungen später Herpes , alle 3 Monate einmal , an der Penishaut ...
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63 Sammlung klinischer Vorträge ... . Innere Medizin: Band ...
https://books.google.com/books?id=4L00AQAAMAAJ&pg=PA632&lpg=PA632&dq=herpes+mhc&source=bl&ots=KwPFy4Z2BO&sig=ACfU3U1wsVucx3QaQLE5RCnawsxzF773jA&hl=en&sa=X&ved=2ahUKEwiQhqygq977AhXvHjQIHfJLCoAQ6AF6BAglEAM
M. H. C. , 31 Jahr alt . 24. ... Schanker 6 monatliche Merkurbehandlung keine Sekundärerscheinungen später Herpes , alle 3 Monate einmal , an der Penishaut ...
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