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Google Keyword Rankings for : restless leg syndrome dopamine deficiency
1
Causes of Restless Legs Syndrome (RLS)
https://www.hopkinsmedicine.org/neurology_neurosurgery/centers_clinics/restless-legs-syndrome/what-is-rls/causes.html
Iron deficiency affects other systems in the brain, which potentially could affect the dopamine systems. Recent work done here at Johns Hopkins suggests another ...
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https://www.hopkinsmedicine.org/neurology_neurosurgery/centers_clinics/restless-legs-syndrome/what-is-rls/causes.html
Iron deficiency affects other systems in the brain, which potentially could affect the dopamine systems. Recent work done here at Johns Hopkins suggests another ...
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2
Peripheral Dopamine in Restless Legs Syndrome - PMC - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862810/
Dopamine is needed to produce smooth, purposeful muscle activity and movement. Disruption of these pathways frequently results in involuntary movements.
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862810/
Dopamine is needed to produce smooth, purposeful muscle activity and movement. Disruption of these pathways frequently results in involuntary movements.
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3
Restless legs syndrome - Illnesses & conditions - NHS inform
https://www.nhsinform.scot/illnesses-and-conditions/brain-nerves-and-spinal-cord/restless-legs-syndrome
If nerve cells become damaged, the amount of dopamine in the brain is reduced, which causes muscle spasms and involuntary movements. Dopamine levels naturally ...
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https://www.nhsinform.scot/illnesses-and-conditions/brain-nerves-and-spinal-cord/restless-legs-syndrome
If nerve cells become damaged, the amount of dopamine in the brain is reduced, which causes muscle spasms and involuntary movements. Dopamine levels naturally ...
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4
How credible are the proposed theories of Restless leg ...
https://www.entvoicesnoring.com/articles/2019/11/15/how-credible-are-the-proposed-theories-of-restless-leg-syndrome-pathophysiology-discuss-and-critically-evaluate-the-evidence
Although a baseline hyperdopaminergic state exists, there is a circadian pattern to dopaminergic activity in restless leg syndrome, with a ...
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https://www.entvoicesnoring.com/articles/2019/11/15/how-credible-are-the-proposed-theories-of-restless-leg-syndrome-pathophysiology-discuss-and-critically-evaluate-the-evidence
Although a baseline hyperdopaminergic state exists, there is a circadian pattern to dopaminergic activity in restless leg syndrome, with a ...
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5
Restless legs syndrome and related disorders - Mount Sinai
https://www.mountsinai.org/health-library/report/restless-legs-syndrome-and-related-disorders
Several studies support the theory that an imbalance in neurotransmitters (chemical messengers in the brain), notably dopamine, may play a part in RLS.
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https://www.mountsinai.org/health-library/report/restless-legs-syndrome-and-related-disorders
Several studies support the theory that an imbalance in neurotransmitters (chemical messengers in the brain), notably dopamine, may play a part in RLS.
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6
Restless legs syndrome: An overview of pathophysiology ...
https://www.spandidos-publications.com/10.3892/etm.2021.11108
Administering a low dose of dopamine at night may be an apparent relief for the patient but it goes in a slippery-slope mechanism of increasing ...
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https://www.spandidos-publications.com/10.3892/etm.2021.11108
Administering a low dose of dopamine at night may be an apparent relief for the patient but it goes in a slippery-slope mechanism of increasing ...
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7
Restless Leg Syndrome and Parkinson's Disease | APDA
https://www.apdaparkinson.org/article/restless-leg-syndrome/
Restless Legs Syndrome (RLS) is a neurologic and sleep-related condition characterized by an irresistible urge to move the legs. The symptoms respond to ...
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https://www.apdaparkinson.org/article/restless-leg-syndrome/
Restless Legs Syndrome (RLS) is a neurologic and sleep-related condition characterized by an irresistible urge to move the legs. The symptoms respond to ...
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8
Restless legs syndrome - Pulmonology Advisor
https://www.pulmonologyadvisor.com/home/decision-support-in-medicine/pulmonary-medicine/restless-legs-syndrome/
RLS patients have brain iron deficiency despite a normal systemic iron status, which leads to dopamine dysfunction that produces the RLS ...
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https://www.pulmonologyadvisor.com/home/decision-support-in-medicine/pulmonary-medicine/restless-legs-syndrome/
RLS patients have brain iron deficiency despite a normal systemic iron status, which leads to dopamine dysfunction that produces the RLS ...
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9
Restless Legs Syndrome: From Pathophysiology to Clinical ...
https://www.frontiersin.org/articles/10.3389/fnagi.2017.00171/full
Iron deficiency in end-stage renal disease patients may lead to anemia and affect the dopamine metabolism, contributing to RLS (Nikic et al., ...
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https://www.frontiersin.org/articles/10.3389/fnagi.2017.00171/full
Iron deficiency in end-stage renal disease patients may lead to anemia and affect the dopamine metabolism, contributing to RLS (Nikic et al., ...
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10
Restless Legs Syndrome - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/nursing-and-health-professions/restless-legs-syndrome
RLS has been linked to deficient iron stores and dopaminergic neurotransmission in the brain and is more common in patients with parkinsonism, ...
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https://www.sciencedirect.com/topics/nursing-and-health-professions/restless-legs-syndrome
RLS has been linked to deficient iron stores and dopaminergic neurotransmission in the brain and is more common in patients with parkinsonism, ...
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11
The night time hustle: managing restless legs syndrome in ...
https://bpac.org.nz/bpj/2012/december/restlesslegs.aspx
Dopaminergic dysfunction and iron deficiency are both thought to have a role in restless legs syndrome. ... The syndrome is also strongly associated with ...
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https://bpac.org.nz/bpj/2012/december/restlesslegs.aspx
Dopaminergic dysfunction and iron deficiency are both thought to have a role in restless legs syndrome. ... The syndrome is also strongly associated with ...
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12
Restless legs syndrome - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/restless-legs-syndrome/symptoms-causes/syc-20377168
Often, there's no known cause for RLS . Researchers suspect the condition may be caused by an imbalance of the brain chemical dopamine, which ...
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https://www.mayoclinic.org/diseases-conditions/restless-legs-syndrome/symptoms-causes/syc-20377168
Often, there's no known cause for RLS . Researchers suspect the condition may be caused by an imbalance of the brain chemical dopamine, which ...
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13
Management of restless legs syndrome and periodic limb ...
https://www.uptodate.com/contents/management-of-restless-legs-syndrome-and-periodic-limb-movement-disorder-in-adults
Dopamine agonists — The non-ergot dopamine agonists, pramipexole, ropinirole, and rotigotine, are effective in the treatment of RLS at low doses ...
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https://www.uptodate.com/contents/management-of-restless-legs-syndrome-and-periodic-limb-movement-disorder-in-adults
Dopamine agonists — The non-ergot dopamine agonists, pramipexole, ropinirole, and rotigotine, are effective in the treatment of RLS at low doses ...
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14
What Causes Restless Legs Syndrome (RLS)? - WebMD
https://www.webmd.com/brain/restless-legs-syndrome/rls-causes
Dopaminergic agents: These drugs, including Sinemet -- a combination of levodopa and carbidopa -- increase the level of dopamine in the brain and may improve ...
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https://www.webmd.com/brain/restless-legs-syndrome/rls-causes
Dopaminergic agents: These drugs, including Sinemet -- a combination of levodopa and carbidopa -- increase the level of dopamine in the brain and may improve ...
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15
Possible Sites of Therapeutic Action in Restless Legs ...
https://www.karger.com/Article/Fulltext/328431
Dopaminergic drugs have shown efficacy as an RLS treatment in numerous large-scale clinical studies [17], and dopamine agonists improve RLS ...
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https://www.karger.com/Article/Fulltext/328431
Dopaminergic drugs have shown efficacy as an RLS treatment in numerous large-scale clinical studies [17], and dopamine agonists improve RLS ...
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16
Dopamine Deficiency: Symptoms, Causes & Treatment
https://my.clevelandclinic.org/health/articles/22588-dopamine-deficiency
Low levels of dopamine have been linked to Parkinson's disease, restless legs syndrome and depression. Low levels of dopamine can make you ...
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https://my.clevelandclinic.org/health/articles/22588-dopamine-deficiency
Low levels of dopamine have been linked to Parkinson's disease, restless legs syndrome and depression. Low levels of dopamine can make you ...
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17
Altered dopaminergic profile in the putamen and substantia ...
https://academic.oup.com/brain/article/132/9/2403/355510
Restless leg syndrome (RLS) is a sensorimotor disorder. Clinical studies have implicated the dopaminergic system in RLS, while others have ...
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https://academic.oup.com/brain/article/132/9/2403/355510
Restless leg syndrome (RLS) is a sensorimotor disorder. Clinical studies have implicated the dopaminergic system in RLS, while others have ...
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18
Restless Legs Syndrome
https://rarediseases.org/rare-diseases/restless-legs-syndrome/
The exact underlying cause of RLS symptoms is unknown. However, many researchers suggest that abnormalities in a certain neurotransmitter (dopamine) in the ...
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https://rarediseases.org/rare-diseases/restless-legs-syndrome/
The exact underlying cause of RLS symptoms is unknown. However, many researchers suggest that abnormalities in a certain neurotransmitter (dopamine) in the ...
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19
Neuroscience for Kids - Restless Legs Syndrome (RLS)
https://faculty.washington.edu/chudler/rls.html
Dopamine deficiency: medications that increase levels of the neurotransmitter dopamine may relieve RLS symptoms. Diagnosis of RLS. There is no blood test or ...
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https://faculty.washington.edu/chudler/rls.html
Dopamine deficiency: medications that increase levels of the neurotransmitter dopamine may relieve RLS symptoms. Diagnosis of RLS. There is no blood test or ...
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20
Restless Legs Syndrome across the Lifespan - MDPI
https://www.mdpi.com/1660-4601/17/10/3658/htm
The dopamine pathophysiology of RLS finds its fundamentals in the discovery of the dramatic response to dopaminergic agents (first levodopa, in the early 1980s, ...
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https://www.mdpi.com/1660-4601/17/10/3658/htm
The dopamine pathophysiology of RLS finds its fundamentals in the discovery of the dramatic response to dopaminergic agents (first levodopa, in the early 1980s, ...
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21
Restless Legs Syndrome - AAFP
https://www.aafp.org/pubs/afp/issues/2008/0715/p235.html
If medications are needed, dopamine agonists are the primary medications for moderate to severe restless legs syndrome.
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https://www.aafp.org/pubs/afp/issues/2008/0715/p235.html
If medications are needed, dopamine agonists are the primary medications for moderate to severe restless legs syndrome.
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22
Imbalance between thyroid hormones and the dopaminergic ...
https://www.scielo.br/j/clin/a/T8HQX8qrm4t7RCwc6tB36kP/?lang=en
Dopamine (DA), when diminished, plays an important role in the pathophysiology of Restless Legs Syndrome (RLS) when decreased DA levels are a primary condition, ...
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https://www.scielo.br/j/clin/a/T8HQX8qrm4t7RCwc6tB36kP/?lang=en
Dopamine (DA), when diminished, plays an important role in the pathophysiology of Restless Legs Syndrome (RLS) when decreased DA levels are a primary condition, ...
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23
Pathophysiology of the Restless Legs Syndrome
https://www.e-jsm.org/journal/view.php?number=30
CNS dopaminergic systems are strongly implicated in RLS that are closely linked to CNS iron homeostasis. Evidences showing the efficacy of dopaminergic drugs, ...
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https://www.e-jsm.org/journal/view.php?number=30
CNS dopaminergic systems are strongly implicated in RLS that are closely linked to CNS iron homeostasis. Evidences showing the efficacy of dopaminergic drugs, ...
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24
Surprising Cause of the Restless Legs Syndrome (RLS)
https://www.healthaid.co.uk/blogs/news/surprising-cause-of-the-restless-legs-syndrome-rls
Deficiency of dopamine is regarded as the most frequent cause of RLS. There is a clear link between RLS and low levels of dopamine in the brain.
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https://www.healthaid.co.uk/blogs/news/surprising-cause-of-the-restless-legs-syndrome-rls
Deficiency of dopamine is regarded as the most frequent cause of RLS. There is a clear link between RLS and low levels of dopamine in the brain.
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25
New Research Identifies Adenosine Role in RLS
http://rlsfoundation.blogspot.com/2018/07/new-research-identifies-adenosine-role.html
It has long been believed that RLS is related to a malfunction in the way the brain uses dopamine. Dopamine is a neurotransmitter (a brain ...
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http://rlsfoundation.blogspot.com/2018/07/new-research-identifies-adenosine-role.html
It has long been believed that RLS is related to a malfunction in the way the brain uses dopamine. Dopamine is a neurotransmitter (a brain ...
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26
Linking restless legs syndrome with Parkinson's disease
https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/2047-9158-1-6
Evidence pointing towards a link includes response to dopaminergic agents in PD and RLS, suggestive of underlying dopamine dysfunction in both ...
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https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/2047-9158-1-6
Evidence pointing towards a link includes response to dopaminergic agents in PD and RLS, suggestive of underlying dopamine dysfunction in both ...
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27
Exploring the Relationship Between Parkinson Disease and ...
https://jamanetwork.com/journals/jamaneurology/fullarticle/781607
RESTLESS LEGS syndrome (RLS) is a common neurological syndrome that is usually either genetic or secondary to other medical conditions, including low iron ...
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https://jamanetwork.com/journals/jamaneurology/fullarticle/781607
RESTLESS LEGS syndrome (RLS) is a common neurological syndrome that is usually either genetic or secondary to other medical conditions, including low iron ...
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28
The Link Between Iron Deficiency and Restless Leg Syndrome
https://veincenterelpaso.com/post/the-link-between-iron-deficiency-and-restless-leg-syndrome
Research shows that RLS symptoms are directly related to how well your brain produces and uses dopamine. When iron levels are low, the brain can ...
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https://veincenterelpaso.com/post/the-link-between-iron-deficiency-and-restless-leg-syndrome
Research shows that RLS symptoms are directly related to how well your brain produces and uses dopamine. When iron levels are low, the brain can ...
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29
What Causes Restless Leg Syndrome (RLS)?
https://www.carolinavein.com/what-causes-restless-leg-syndrome-rls/
Dopamine is a chemical used by brain cells to communicate and produce smooth, purposeful muscle activity and movement. As dopamine levels ...
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https://www.carolinavein.com/what-causes-restless-leg-syndrome-rls/
Dopamine is a chemical used by brain cells to communicate and produce smooth, purposeful muscle activity and movement. As dopamine levels ...
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30
The Management of Restless Legs Syndrome: An Updated ...
https://www.mayoclinicproceedings.org/article/S0025-6196(20)31489-0/fulltext
The choice of an alpha2-delta ligand as first-line therapy for chronic persistent RLS with dopamine agonists as a second-line option is ...
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https://www.mayoclinicproceedings.org/article/S0025-6196(20)31489-0/fulltext
The choice of an alpha2-delta ligand as first-line therapy for chronic persistent RLS with dopamine agonists as a second-line option is ...
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31
Dopamine and Iron in Restless Legs Syndrome - Grantome
https://grantome.com/grant/NIH/R01-NS042857-01A1
Like Parkinson's disease, restless legs syndrome is exquisitely sensitive to dopamine agents and aggravated or precipitated by dopamine antagonists.
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https://grantome.com/grant/NIH/R01-NS042857-01A1
Like Parkinson's disease, restless legs syndrome is exquisitely sensitive to dopamine agents and aggravated or precipitated by dopamine antagonists.
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32
2-Minute Neuroscience: Restless Legs Syndrome - YouTube
https://www.youtube.com/watch?v=D6WmNTQTAfc
Neuroscientifically Challenged
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https://www.youtube.com/watch?v=D6WmNTQTAfc
Neuroscientifically Challenged
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33
Restless Legs Syndrome | Diagnosis & Treatment - UCHealth
https://www.uchealth.org/diseases-conditions/restless-legs-syndrome/
Iron deficiency. Low levels of iron in the blood or brain can lead to lower dopamine levels, which can cause RLS. People with heavy menstrual periods or who ...
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https://www.uchealth.org/diseases-conditions/restless-legs-syndrome/
Iron deficiency. Low levels of iron in the blood or brain can lead to lower dopamine levels, which can cause RLS. People with heavy menstrual periods or who ...
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34
Remedies for Restless Legs Syndrome - Dr Wholeness
https://drwholeness.com/blog/remedies-for-restless-leg-syndrome/
One study actually demonstrated a 4x difference between daytime dopamine and night time dopamine levels in people with restless leg syndrome. In ...
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https://drwholeness.com/blog/remedies-for-restless-leg-syndrome/
One study actually demonstrated a 4x difference between daytime dopamine and night time dopamine levels in people with restless leg syndrome. In ...
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35
Neurochemistry of Idiopathic Restless Legs Syndrome
https://touchneurology.com/movement-disorders/journal-articles/neurochemistry-of-idiopathic-restless-legs-syndrome/
The excellent therapeutic response of RLS to dopaminergic drugs, together with some neuropathological, neuroimaging, biochemical and ...
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https://touchneurology.com/movement-disorders/journal-articles/neurochemistry-of-idiopathic-restless-legs-syndrome/
The excellent therapeutic response of RLS to dopaminergic drugs, together with some neuropathological, neuroimaging, biochemical and ...
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36
Practice Parameters for the Dopaminergic Treatment of ...
https://aasm.org/resources/practiceparameters/pp_dt_rlsplmd.pdf
RESTLESS LEGS SYNDROME (RLS) AND PERIODIC LIMB. MOVEMENT DISORDER (PLMD) HAVE PRIMARILY ... more common in conditions with dopamine deficiency [22] and less.
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https://aasm.org/resources/practiceparameters/pp_dt_rlsplmd.pdf
RESTLESS LEGS SYNDROME (RLS) AND PERIODIC LIMB. MOVEMENT DISORDER (PLMD) HAVE PRIMARILY ... more common in conditions with dopamine deficiency [22] and less.
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37
Restless Legs Syndrome: How to Fight a Condition That's ...
https://www.muhealth.org/our-stories/restless-legs-syndrome-how-fight-condition-thats-stealing-your-sleep
If iron deficiency is not the cause, there are treatments to lessen the symptoms of restless legs syndrome. Dopamine agonist drugs such as ropinirole and ...
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https://www.muhealth.org/our-stories/restless-legs-syndrome-how-fight-condition-thats-stealing-your-sleep
If iron deficiency is not the cause, there are treatments to lessen the symptoms of restless legs syndrome. Dopamine agonist drugs such as ropinirole and ...
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38
8 Restless Legs Syndrome Triggers | Everyday Health
https://www.everydayhealth.com/sleep-disorders/restless-leg-syndrome/8-restless-legs-syndrome-triggers/
Although it's not known what causes RLS, research suggests it's related to a dysfunction in the brain's basal ganglia, a group of nerve cells ...
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https://www.everydayhealth.com/sleep-disorders/restless-leg-syndrome/8-restless-legs-syndrome-triggers/
Although it's not known what causes RLS, research suggests it's related to a dysfunction in the brain's basal ganglia, a group of nerve cells ...
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39
The 11 Best Treatments for Restless Legs Syndrome
https://www.healthline.com/health/restless-leg-syndrome/treatments
Because of the effects RLS can have on your life, treatment is important. Methods of treatment are varied, as the root cause of RLS isn't truly known. For ...
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https://www.healthline.com/health/restless-leg-syndrome/treatments
Because of the effects RLS can have on your life, treatment is important. Methods of treatment are varied, as the root cause of RLS isn't truly known. For ...
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40
Restless Leg Syndrome - Symptoms and Causes
https://www.pennmedicine.org/for-patients-and-visitors/patient-information/conditions-treated-a-to-z/restless-leg-syndrome
No one knows exactly what causes RLS. It may be due to a problem with the way brain cells use dopamine. Dopamine is a brain chemical that helps with muscle ...
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https://www.pennmedicine.org/for-patients-and-visitors/patient-information/conditions-treated-a-to-z/restless-leg-syndrome
No one knows exactly what causes RLS. It may be due to a problem with the way brain cells use dopamine. Dopamine is a brain chemical that helps with muscle ...
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41
Restless Legs Syndrome: Contemporary Diagnosis and ...
https://link.springer.com/article/10.1007/s13311-021-01019-4
Since dopamine agonists relieve RLS symptoms, it may be reasonably anticipated that brain dopamine levels should be low in RLS patients. However ...
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https://link.springer.com/article/10.1007/s13311-021-01019-4
Since dopamine agonists relieve RLS symptoms, it may be reasonably anticipated that brain dopamine levels should be low in RLS patients. However ...
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42
The Adenosine Hypothesis of Restless Legs Syndrome
https://www.liebertpub.com/doi/10.1089/caff.2019.0001
Counterintuitively, in the frame of a presynaptic hyperdopaminergic state, dopamine agonists, such as pramipexole and ropinirole, are clinically ...
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https://www.liebertpub.com/doi/10.1089/caff.2019.0001
Counterintuitively, in the frame of a presynaptic hyperdopaminergic state, dopamine agonists, such as pramipexole and ropinirole, are clinically ...
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43
Restless legs syndrome: MedlinePlus Medical Encyclopedia
https://medlineplus.gov/ency/article/000807.htm
No one knows exactly what causes RLS. It may be due to a problem with the way brain cells use dopamine. Dopamine is a brain chemical that helps ...
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https://medlineplus.gov/ency/article/000807.htm
No one knows exactly what causes RLS. It may be due to a problem with the way brain cells use dopamine. Dopamine is a brain chemical that helps ...
→ Check Latest Keyword Rankings ←
44
Calming Restless Legs Syndrome | Henry Ford Health
https://www.henryford.com/blog/2019/08/calming-restless-legs-syndrome
“Restless Legs Syndrome is very common due to anemia and the natural aging process of the brain,” he says. “Your brain needs dopamine, ...
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https://www.henryford.com/blog/2019/08/calming-restless-legs-syndrome
“Restless Legs Syndrome is very common due to anemia and the natural aging process of the brain,” he says. “Your brain needs dopamine, ...
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45
Restless legs syndrome - Ekbom - 2009 - Wiley Online Library
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2796.2009.02159.x
Dopamine. According to a commonly held view RLS may be due to dysfunction of dopamine cells in the nigro-striatal areas of the brain.
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https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2796.2009.02159.x
Dopamine. According to a commonly held view RLS may be due to dysfunction of dopamine cells in the nigro-striatal areas of the brain.
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46
Restless Legs Syndrome and Mood Disorders - Psychiatrist.com
https://www.psychiatrist.com/jcp/bipolar/mood-disorders/mood-disorders-restless-legs-syndrome-willis-ekbom/
As previously mentioned, dopaminergic treatment may have beneficial effects on comorbid mood disorders in addition to improving symptoms of RLS.
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https://www.psychiatrist.com/jcp/bipolar/mood-disorders/mood-disorders-restless-legs-syndrome-willis-ekbom/
As previously mentioned, dopaminergic treatment may have beneficial effects on comorbid mood disorders in addition to improving symptoms of RLS.
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47
Restless Legs Syndrome: Current Concepts about Disease ...
https://tremorjournal.org/article/10.5334/tohm.322/
Pathologically, the most consistent finding is striatal iron deficiency in RLS patients. A host of other biological systems are also altered in ...
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https://tremorjournal.org/article/10.5334/tohm.322/
Pathologically, the most consistent finding is striatal iron deficiency in RLS patients. A host of other biological systems are also altered in ...
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48
New Insights into the Neurobiology of Restless Legs Syndrome
https://journals.sagepub.com/doi/10.1177/1073858418791763
The dopaminergic profile in RLS patients includes abnormally high cerebrospinal fluid levels of the dopamine metabolite 3-OMD, interpreted to indicate increased ...
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https://journals.sagepub.com/doi/10.1177/1073858418791763
The dopaminergic profile in RLS patients includes abnormally high cerebrospinal fluid levels of the dopamine metabolite 3-OMD, interpreted to indicate increased ...
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49
Restless legs syndrome - RCP Journals
https://www.rcpjournals.org/content/clinmedicine/16/4/379
The pathophysiology is only partially known and a genetic component together with dopaminergic and brain iron dysregulation plays an important role. Secondary ...
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https://www.rcpjournals.org/content/clinmedicine/16/4/379
The pathophysiology is only partially known and a genetic component together with dopaminergic and brain iron dysregulation plays an important role. Secondary ...
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50
Restless Leg Syndrome | Michigan Medicine
https://www.uofmhealth.org/conditions-treatments/brain-neurological-conditions/restless-leg-syndrome
Iron deficiency (anemia); Kidney failure; Diabetes mellitus; Rheumatoid arthritis; Peripheral neuropathy; Parkinson's disease; Pregnancy. The following may make ...
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https://www.uofmhealth.org/conditions-treatments/brain-neurological-conditions/restless-leg-syndrome
Iron deficiency (anemia); Kidney failure; Diabetes mellitus; Rheumatoid arthritis; Peripheral neuropathy; Parkinson's disease; Pregnancy. The following may make ...
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51
Efficacy of Tyrosine in Restless Legs Syndrome - Full Text View
https://clinicaltrials.gov/ct2/show/NCT01494766
It is well known that dopamine deficiency leads to the manifestations of restless legs syndrome (RLS). Studies have shown dopamine agonists ...
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https://clinicaltrials.gov/ct2/show/NCT01494766
It is well known that dopamine deficiency leads to the manifestations of restless legs syndrome (RLS). Studies have shown dopamine agonists ...
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52
An Updated Algorithm - Restless Legs Syndrome Foundation
https://www.rls.org/21Algorithm
persistent RLS with dopamine agonists as a second-line option is explained. ... saturation <20% may be a more accurate measure of iron deficiency.).
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https://www.rls.org/21Algorithm
persistent RLS with dopamine agonists as a second-line option is explained. ... saturation <20% may be a more accurate measure of iron deficiency.).
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53
Dopamine deficiency: Symptoms, causes, and treatment
https://www.medicalnewstoday.com/articles/320637
Parkinson's disease · restless leg syndrome; neuroleptic malignant syndrome, a rare side effect of antipsychotic medication; hyperprolactinemia, a condition ...
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https://www.medicalnewstoday.com/articles/320637
Parkinson's disease · restless leg syndrome; neuroleptic malignant syndrome, a rare side effect of antipsychotic medication; hyperprolactinemia, a condition ...
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54
Restless Leg Syndrome - FPnotebook
https://fpnotebook.com/mobile/neuro/motor/RstlsLgSyndrm.htm
Restless Leg Syndrome · Dopamine deficiency in Brainstem or spinal cord · Endogenous Opiate deficiency · Small fiber Peripheral Neuropathy.
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https://fpnotebook.com/mobile/neuro/motor/RstlsLgSyndrm.htm
Restless Leg Syndrome · Dopamine deficiency in Brainstem or spinal cord · Endogenous Opiate deficiency · Small fiber Peripheral Neuropathy.
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55
Restless Legs Syndrome - Medscape Reference
https://emedicine.medscape.com/article/1188327-overview
Results of single-photon emission computed tomography (SPECT) have suggested a deficiency of dopamine D2 receptors. Iron homeostasis ...
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https://emedicine.medscape.com/article/1188327-overview
Results of single-photon emission computed tomography (SPECT) have suggested a deficiency of dopamine D2 receptors. Iron homeostasis ...
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56
Restless Legs Syndrome: Symptoms, Causes, and Treatments
https://sleepopolis.com/education/restless-leg-syndrome/
Dopamine dysfunction. There is strong evidence to suggest that RLS may result from an imbalance of dopamine, a brain chemical involved in ...
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https://sleepopolis.com/education/restless-leg-syndrome/
Dopamine dysfunction. There is strong evidence to suggest that RLS may result from an imbalance of dopamine, a brain chemical involved in ...
→ Check Latest Keyword Rankings ←
57
Symptom Persistence after Iron Normalization in Women with ...
https://www.psychiatryinvestigation.org/m/journal/view.php?number=847
Among possible pathophysiology of primary RLS, brain iron deficiency and central dopamine dysfunction have been suggested. Serum ferritin level ...
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https://www.psychiatryinvestigation.org/m/journal/view.php?number=847
Among possible pathophysiology of primary RLS, brain iron deficiency and central dopamine dysfunction have been suggested. Serum ferritin level ...
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58
Restless Legs Syndrome - Baylor College of Medicine
https://www.bcm.edu/healthcare/specialties/neurology/parkinsons-disease-and-movement-disorders/restless-legs-syndrome
A series of other dopamine drugs called agonists (dopamine mimickers) have since been shown to markedly improve RLS symptoms, often more than Sinemet. These ...
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https://www.bcm.edu/healthcare/specialties/neurology/parkinsons-disease-and-movement-disorders/restless-legs-syndrome
A series of other dopamine drugs called agonists (dopamine mimickers) have since been shown to markedly improve RLS symptoms, often more than Sinemet. These ...
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59
Restless Leg Syndrome Medication Treatment Options - Health
https://www.health.com/condition/sleep/medication-for-rls-the-pros-and-cons-of-dopamine-agonists-and-other-treatments
Because RLS seems to be caused by a dopamine shortage in the brain, Requip and Mirapex—taken an hour or two before bed—improve nighttime ...
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https://www.health.com/condition/sleep/medication-for-rls-the-pros-and-cons-of-dopamine-agonists-and-other-treatments
Because RLS seems to be caused by a dopamine shortage in the brain, Requip and Mirapex—taken an hour or two before bed—improve nighttime ...
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60
Controversies and Challenges in Defining the Etiology and ...
https://www.amjmed.com/article/S0002-9343(06)01294-0/abstract
Restless legs syndrome (RLS) can occur as a primary disorder, with no apparent cause other than a possible genetic predisposition, or as a secondary ...
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https://www.amjmed.com/article/S0002-9343(06)01294-0/abstract
Restless legs syndrome (RLS) can occur as a primary disorder, with no apparent cause other than a possible genetic predisposition, or as a secondary ...
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61
Is Vein Disease Causing Restless Leg Syndrome?
https://niveinclinic.com/is-vein-disease-causing-restless-legs-syndrome/
One of these chemicals, dopamine, plays a role in controlling muscle movements in the body. RLS may happen when dopamine levels are imbalanced, ...
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https://niveinclinic.com/is-vein-disease-causing-restless-legs-syndrome/
One of these chemicals, dopamine, plays a role in controlling muscle movements in the body. RLS may happen when dopamine levels are imbalanced, ...
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62
Restless Legs Syndrome - Hormones Matter
http://www.hormonesmatter.com/restless-legs-syndrome/
Levodopa is converted into dopamine in the body, and therefore it was thought that RLS resulted from a deficiency of dopamine, ...
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http://www.hormonesmatter.com/restless-legs-syndrome/
Levodopa is converted into dopamine in the body, and therefore it was thought that RLS resulted from a deficiency of dopamine, ...
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63
Restless Legs Syndrome | FX Medicine
https://www.fxmedicine.com.au/blog-post/restless-legs-syndrome
Treatment strategies for RLS include correcting iron deficiency, supporting dopamine synthesis and improving relaxation and quality of sleep ...
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https://www.fxmedicine.com.au/blog-post/restless-legs-syndrome
Treatment strategies for RLS include correcting iron deficiency, supporting dopamine synthesis and improving relaxation and quality of sleep ...
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64
Restless legs syndrome in Parkinson disease - Nature
https://www.nature.com/articles/s41598-017-10593-7
PD-RLS was common and severer in motor and some non-motor symptoms. Iron deficiency induced by its metabolism dysfunctions in peripheral and ...
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https://www.nature.com/articles/s41598-017-10593-7
PD-RLS was common and severer in motor and some non-motor symptoms. Iron deficiency induced by its metabolism dysfunctions in peripheral and ...
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65
Full article: Restless legs syndrome: differential diagnosis and ...
https://www.tandfonline.com/doi/full/10.2147/cia.s4143
In particular, dopamine dysfunction plays a central role, as suggested by the early observation that dopaminergic drugs are highly effective in ...
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https://www.tandfonline.com/doi/full/10.2147/cia.s4143
In particular, dopamine dysfunction plays a central role, as suggested by the early observation that dopaminergic drugs are highly effective in ...
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66
The Dopamine Connection Between ADHD and RLS
https://restlesslegssyndrome.sleep-disorders.net/living/adhd-dopamine
Dopamine levels and iron levels in the body can play a common role in children and adults who are diagnosed with ADHD and restless legs ...
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https://restlesslegssyndrome.sleep-disorders.net/living/adhd-dopamine
Dopamine levels and iron levels in the body can play a common role in children and adults who are diagnosed with ADHD and restless legs ...
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67
Restless Leg Syndrome: Symptoms and Causes
https://www.mattressadvisor.com/restless-leg-syndrome/
Dopamine is involved in purposeful muscle movements, and some RLS patients experience symptoms as a result of a dopamine deficiency.
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https://www.mattressadvisor.com/restless-leg-syndrome/
Dopamine is involved in purposeful muscle movements, and some RLS patients experience symptoms as a result of a dopamine deficiency.
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68
Restless legs syndrome - RACGP
https://www.racgp.org.au/getattachment/87576673-c695-48f6-a806-065da7e5fcc7/Restless-legs-syndrome.aspx
to pharmacotherapy (eg. dopamine agonists, levodopa, opioids,. Background. Restless legs syndrome (RLS) is a common, but frequently.
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https://www.racgp.org.au/getattachment/87576673-c695-48f6-a806-065da7e5fcc7/Restless-legs-syndrome.aspx
to pharmacotherapy (eg. dopamine agonists, levodopa, opioids,. Background. Restless legs syndrome (RLS) is a common, but frequently.
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69
Dopamine D3 Receptor Specifically Modulates Motor and ...
https://www.jneurosci.org/content/31/1/70
As iron deficiency has been associated with RLS for some patients and there is evidence for decreased spinal dopamine D3-receptor (D3R) ...
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https://www.jneurosci.org/content/31/1/70
As iron deficiency has been associated with RLS for some patients and there is evidence for decreased spinal dopamine D3-receptor (D3R) ...
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70
The ABCs of RLS: Restless Legs Syndrome - tl;dr pharmacy
https://www.tldrpharmacy.com/content/the-abcs-of-rls-restless-legs-syndrome
If symptoms are reduced by at least 50%, then the patient is determined to have RLS. Due to this responsiveness, the dopaminergic pathway has ...
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https://www.tldrpharmacy.com/content/the-abcs-of-rls-restless-legs-syndrome
If symptoms are reduced by at least 50%, then the patient is determined to have RLS. Due to this responsiveness, the dopaminergic pathway has ...
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71
Restless Leg Syndrome - National Nutrition Articles
https://www.nationalnutrition.ca/articles/health-concerns/restless-leg-syndrome/
Many prescription medications are also based on increasing dopamine stores and its production in the brain. As dopamine is a chemical messenger that controls ...
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https://www.nationalnutrition.ca/articles/health-concerns/restless-leg-syndrome/
Many prescription medications are also based on increasing dopamine stores and its production in the brain. As dopamine is a chemical messenger that controls ...
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72
Signs of restless legs syndrome - Ada Health
https://ada.com/conditions/restless-legs-syndrome/
Restless legs syndrome (RLS), also known as Willis-Ekbom disease, is a chronic condition that causes strong, unpleasant feelings in the legs, ...
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https://ada.com/conditions/restless-legs-syndrome/
Restless legs syndrome (RLS), also known as Willis-Ekbom disease, is a chronic condition that causes strong, unpleasant feelings in the legs, ...
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73
Restless Leg Syndrome - Life Extension
https://www.lifeextension.com/protocols/neurological/restless-leg-syndrome
RLS can be classified as primary or secondary; the exact cause of primary RLS is not known, although altered dopamine signaling is thought to play a part, while ...
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https://www.lifeextension.com/protocols/neurological/restless-leg-syndrome
RLS can be classified as primary or secondary; the exact cause of primary RLS is not known, although altered dopamine signaling is thought to play a part, while ...
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74
Understanding Restless Legs Syndrome | Franciscan Health
https://www.franciscanhealth.org/community/blog/restless-leg-syndrome
“There is no known, definitive cause for restless legs syndrome, though researchers believe it may be linked to dopamine imbalances in the ...
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https://www.franciscanhealth.org/community/blog/restless-leg-syndrome
“There is no known, definitive cause for restless legs syndrome, though researchers believe it may be linked to dopamine imbalances in the ...
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75
Hidden Causes of Restless Legs Syndrome | Amy Myers MD
https://www.amymyersmd.com/article/causes-restless-legs-syndrome/
Dopamine Imbalance · Kidney Disease · Iron Deficiency · Diabetes · Rheumatoid Arthritis · Pregnancy · Diet.
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https://www.amymyersmd.com/article/causes-restless-legs-syndrome/
Dopamine Imbalance · Kidney Disease · Iron Deficiency · Diabetes · Rheumatoid Arthritis · Pregnancy · Diet.
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76
Restless legs syndrome - Wikipedia
https://en.wikipedia.org/wiki/Restless_legs_syndrome
Restless legs syndrome (RLS), also known as Willis-Ekbom disease (WED), is generally a long-term disorder that causes a strong urge to move one's legs.
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https://en.wikipedia.org/wiki/Restless_legs_syndrome
Restless legs syndrome (RLS), also known as Willis-Ekbom disease (WED), is generally a long-term disorder that causes a strong urge to move one's legs.
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77
Restless Legs Syndrome - MDPI
https://mdpi-res.com/d_attachment/brainsci/brainsci-12-00118/article_deploy/brainsci-12-00118.pdf?version=1642332928
circadian disorders; dopamine; iron; sensory gating. 1. Introduction. Restless legs syndrome (RLS) is a common neurological disorder ...
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https://mdpi-res.com/d_attachment/brainsci/brainsci-12-00118/article_deploy/brainsci-12-00118.pdf?version=1642332928
circadian disorders; dopamine; iron; sensory gating. 1. Introduction. Restless legs syndrome (RLS) is a common neurological disorder ...
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78
Understanding and Relieving Restless Legs Syndrome
https://www.uspharmacist.com/article/understanding-and-relieving-restless-legs-syndrome
Dopamine is necessary for the successful use of muscles to produce purposeful movement. As in Parkinson's disease, the brain's ability to use ...
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https://www.uspharmacist.com/article/understanding-and-relieving-restless-legs-syndrome
Dopamine is necessary for the successful use of muscles to produce purposeful movement. As in Parkinson's disease, the brain's ability to use ...
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79
Restless legs syndrome - Australian Prescriber
https://www.nps.org.au/australian-prescriber/articles/restless-legs-syndrome-1
Restless legs syndrome is a common but under-recognised disorder. For patients with mild symptoms, no drug treatment may be necessary. For patients with severe ...
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https://www.nps.org.au/australian-prescriber/articles/restless-legs-syndrome-1
Restless legs syndrome is a common but under-recognised disorder. For patients with mild symptoms, no drug treatment may be necessary. For patients with severe ...
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80
The Treatment and Management of Restless Legs Syndrome
https://www.medscape.org/viewarticle/522010_6
Dopamine Agonists. The most commonly prescribed dopamine agonists for RLS are pramipexole and ropinirole. Both are nonergots, and have been determined to be ...
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https://www.medscape.org/viewarticle/522010_6
Dopamine Agonists. The most commonly prescribed dopamine agonists for RLS are pramipexole and ropinirole. Both are nonergots, and have been determined to be ...
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81
The Real Causes of Restless Legs Syndrome - Dave Asprey
https://daveasprey.com/restless-leg-syndrome-natural-remedies-10-04-19/
It's not entirely clear what causes RLS, but genes do play a role. Iron deficiency in the brain, lack of sleep, and dopamine shortage may also be to blame.
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https://daveasprey.com/restless-leg-syndrome-natural-remedies-10-04-19/
It's not entirely clear what causes RLS, but genes do play a role. Iron deficiency in the brain, lack of sleep, and dopamine shortage may also be to blame.
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82
Restless legs syndrome - Sparrow Health System
https://www.sparrow.org/departments-conditions/conditions/restless-legs-syndrome
Often, there's no known cause for RLS . Researchers suspect the condition may be caused by an imbalance of the brain chemical dopamine, ...
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https://www.sparrow.org/departments-conditions/conditions/restless-legs-syndrome
Often, there's no known cause for RLS . Researchers suspect the condition may be caused by an imbalance of the brain chemical dopamine, ...
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83
Restless Legs Syndrome - 4 Less-Known Causes
https://chriskresser.com/4-little-known-causes-of-restless-legs-syndrome/
Pinpointing the cause of RLS has been an active research topic for years, but the condition is still not fully understood. The symptoms have been convincingly ...
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https://chriskresser.com/4-little-known-causes-of-restless-legs-syndrome/
Pinpointing the cause of RLS has been an active research topic for years, but the condition is still not fully understood. The symptoms have been convincingly ...
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84
Restless leg syndrome - NHS 111 Wales
https://111.wales.nhs.uk/encyclopaedia/r/article/restlesslegsyndrome/
Dopamine agonists may be recommended if you're experiencing frequent symptoms of restless legs syndrome. They work by increasing dopamine levels ...
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https://111.wales.nhs.uk/encyclopaedia/r/article/restlesslegsyndrome/
Dopamine agonists may be recommended if you're experiencing frequent symptoms of restless legs syndrome. They work by increasing dopamine levels ...
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85
Restless Legs Syndrome: Symptoms and Treatment
https://www.livescience.com/34791-restless-legs-syndrome-symptoms-treatment.html
In many cases, the cause of RLS is unknown. However, research points to three factors: iron deficiency, lower dopamine production and heredity, ...
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https://www.livescience.com/34791-restless-legs-syndrome-symptoms-treatment.html
In many cases, the cause of RLS is unknown. However, research points to three factors: iron deficiency, lower dopamine production and heredity, ...
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86
Restless Legs Syndrome: Clinical Implications for Psychiatrists
https://www.psychiatrictimes.com/view/restless-legs-syndrome-clinical-implications-psychiatrists
Iron's ability to modulate dopamine neurotransmission further informs clinical observations that RLS symptoms are reduced or resolved with the ...
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https://www.psychiatrictimes.com/view/restless-legs-syndrome-clinical-implications-psychiatrists
Iron's ability to modulate dopamine neurotransmission further informs clinical observations that RLS symptoms are reduced or resolved with the ...
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87
The protein profile of restless leg syndrome - ScienceDaily
https://www.sciencedaily.com/releases/2013/06/130606223248.htm
It is not completely clear what causes RLS, also known as Willis Ekbom disease (WED), but in some people it is associated with iron deficiency ...
→ Check Latest Keyword Rankings ←
https://www.sciencedaily.com/releases/2013/06/130606223248.htm
It is not completely clear what causes RLS, also known as Willis Ekbom disease (WED), but in some people it is associated with iron deficiency ...
→ Check Latest Keyword Rankings ←
88
Restless legs syndrome - Knowledge @ AMBOSS
https://www.amboss.com/us/knowledge/Restless_legs_syndrome/
The pathophysiology of RLS remains unclear. Studies suggest that abnormal dopamine pathways in the brain and impaired iron homeostasis (leading ...
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https://www.amboss.com/us/knowledge/Restless_legs_syndrome/
The pathophysiology of RLS remains unclear. Studies suggest that abnormal dopamine pathways in the brain and impaired iron homeostasis (leading ...
→ Check Latest Keyword Rankings ←
89
Clinical Trial on Restless Legs Syndrome (RLS): L-Tyrosine
https://ichgcp.net/clinical-trials-registry/NCT01494766
It is well known that dopamine deficiency leads to the manifestations of restless legs syndrome (RLS). Studies have shown dopamine agonists and L-dopa to be ...
→ Check Latest Keyword Rankings ←
https://ichgcp.net/clinical-trials-registry/NCT01494766
It is well known that dopamine deficiency leads to the manifestations of restless legs syndrome (RLS). Studies have shown dopamine agonists and L-dopa to be ...
→ Check Latest Keyword Rankings ←
90
Restless Legs Syndrome as the Initial Presentation of Multiple ...
https://www.hindawi.com/journals/crim/2013/290719/
It is associated with several pathological or physiological conditions. Iron metabolism and dysfunctions of the dopaminergic system are the most important ...
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https://www.hindawi.com/journals/crim/2013/290719/
It is associated with several pathological or physiological conditions. Iron metabolism and dysfunctions of the dopaminergic system are the most important ...
→ Check Latest Keyword Rankings ←
91
Do I Have Restless Legs Syndrome?
https://www.thensf.org/do-i-have-restless-legs-syndrome/
This part of the brain relies on a chemical called dopamine to signal to the muscles that it's time to act. In normal circumstances, dopamine ...
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https://www.thensf.org/do-i-have-restless-legs-syndrome/
This part of the brain relies on a chemical called dopamine to signal to the muscles that it's time to act. In normal circumstances, dopamine ...
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92
What Causes Restless Legs Syndrome and What Are the ...
https://www.veinhealthclinics.com/blog/what-causes-restless-legs-syndrome-and-what-are-the-treatment-options/
These areas are activated by a neurotransmitter called dopamine, which is essential for producing purposeful and smooth muscle movements. Any ...
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https://www.veinhealthclinics.com/blog/what-causes-restless-legs-syndrome-and-what-are-the-treatment-options/
These areas are activated by a neurotransmitter called dopamine, which is essential for producing purposeful and smooth muscle movements. Any ...
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93
What is Restless-leg Syndrome? - SuperPharmacy
https://www.superpharmacy.com.au/blog/restless-leg-syndrome
Dopamine deficiency or excess ... Dopamine is a feel-good hormone that helps a part of the brain called the basal ganglia to function at its best.
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https://www.superpharmacy.com.au/blog/restless-leg-syndrome
Dopamine deficiency or excess ... Dopamine is a feel-good hormone that helps a part of the brain called the basal ganglia to function at its best.
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94
Restless Legs Syndrome | McGovern Medical School
https://med.uth.edu/neurosciences/conditions-and-treatments/sleep-disorders/restless-legs-syndrome/
About 10 percent of Americans have experienced RLS symptoms. Researchers believe that an imbalance of dopamine, a chemical in the brain that sends messages to ...
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https://med.uth.edu/neurosciences/conditions-and-treatments/sleep-disorders/restless-legs-syndrome/
About 10 percent of Americans have experienced RLS symptoms. Researchers believe that an imbalance of dopamine, a chemical in the brain that sends messages to ...
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95
Restless legs syndrome: Treatment overview - Allen Press
https://meridian.allenpress.com/mhc/article/2/2/37/36883/Restless-legs-syndrome-Treatment-overview
RLS has been linked to iron deficiency in the body, particularly within dopamine containing neurons. ... Magnetic resonance imaging, studies of ...
→ Check Latest Keyword Rankings ←
https://meridian.allenpress.com/mhc/article/2/2/37/36883/Restless-legs-syndrome-Treatment-overview
RLS has been linked to iron deficiency in the body, particularly within dopamine containing neurons. ... Magnetic resonance imaging, studies of ...
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96
Restless Leg Syndrome (RLS) - Houston Methodist
https://www.houstonmethodist.org/neurology/movement-functional-disorders/restless-legs-syndrome/
Researchers suspect that RLS may be caused by an imbalance in dopamine, a brain chemical that used to control muscle movement, but the cause is not known at ...
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https://www.houstonmethodist.org/neurology/movement-functional-disorders/restless-legs-syndrome/
Researchers suspect that RLS may be caused by an imbalance in dopamine, a brain chemical that used to control muscle movement, but the cause is not known at ...
→ Check Latest Keyword Rankings ←
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