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1 Phenytoin-induced bradycardia and hypotension - PMC - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533925/
Bradycardia and hypotension following intravenous (IV) phenytoin are rare ADRs. We report the case of a 62-year-old female with subarachnoid hemorrhage and ...
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2 Dopamine-Phenytoin Interaction: A Cause of Hypotension in ...
https://jamanetwork.com/journals/jamasurgery/fullarticle/583734
In animals rendered hypovolemic and hypotensive by bleeding, intravenous dopamine returned the blood pressure to the prebleeding level. At this point, an ...
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3 Adverse events associated with intravenous phenytoin in ...
https://www.sciencedirect.com/science/article/pii/S1059131102003382
Phenytoin infusion in hypotensive dogs on pressor support caused a significant decrease in systemic vascular resistance (P < 0.0001) and a substantial decrease ...
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4 Phenytoin and Fosphenytoin Toxicity - Emergency Management
https://www.dynamed.com/management/phenytoin-and-fosphenytoin-toxicity-emergency-management
Phenytoin is a commonly used therapeutic agent for treatment and ... common than with IV phenytoin, IV fosphenytoin has been associated with hypotension and ...
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5 PHENYTOIN TOXICITY - Emergency Medicine Journal
http://www.emjournal.net/htdocs/pages/art/45-phtox.html
Phenytoin is a primary anticonvulsant for all types of epilepsy except ... This slower distribution into tissue is further evidence that hypotension and ...
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6 Parenteral Dilantin® (Phenytoin Sodium Injection, USP ...
https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/010151s036lbl.pdf
Dilantin (phenytoin sodium) Injection. FDA Approved Labeling Text dated 10/2011. Page 4 of 14. Adverse cardiovascular reactions include severe hypotension ...
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7 Phenytoin: Generic, Uses, Side Effects, Dosages ... - RxList
https://www.rxlist.com/consumer_phenytoin_dilantin_phenytek/drugs-condition.htm
Phenytoin is used to prevent and control seizures (also called an anticonvulsant or ... Risk of low blood pressure (hypotension) and irregular heartbeats ...
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8 Persistent Bradycardia with the Long-term Use of Phenytoin ...
https://www.cureus.com/articles/10546-persistent-bradycardia-with-the-long-term-use-of-phenytoin-and-oxycodone-first-case-report
Some adverse cardiac manifestations have also been reported, including arrhythmias, hypotension, and respiratory arrest. Oxycodone is an opioid ...
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9 Intracranial Changes Secondary to Prolonged Phenytoin ...
https://journals.sagepub.com/doi/10.1177/197140090601900210
1. Cousins MJ, Brazier D, Cook R: Intracranial hypotension caused by cervical cerebrospinal fluid leak: Treatment with epidural blood patch. Anesth Analg 98: ...
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10 Phenytoin - Wikipedia
https://en.wikipedia.org/wiki/Phenytoin
Phenytoin (PHT), sold under the brand name Dilantin among others, is an anti-seizure ... self harm, liver problems, bone marrow suppression, low blood pressure, ...
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11 Convulsive status epilepticus in adults: Management
https://www.uptodate.com/contents/convulsive-status-epilepticus-in-adults-management
Hypotension may also result from benzodiazepines, barbiturates, ... ○For a patient on phenytoin treatment prior to the onset of GCSE who is ...
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12 Phenytoin Sodium - Starship
https://starship.org.nz/guidelines/phenytoin-sodium
Precautions. Known hypersensitivity to phenytoin. Neonates with jaundice, respiratory failure, hypotension or heart failure. Preterm infants, ...
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13 DOSE-DRIVEN INFUSION TIMES AND CARDIOVASCULAR ...
https://journal.chestnet.org/article/S0012-3692(20)32812-9/pdf
helps to reduce the risk of hypotension. At our institution, a phenytoin loading dose of 1000 mg over 30 minutes (33 mg/min) is.
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14 Clinical Practice Guidelines : Phenytoin poisoning
https://www.rch.org.au/clinicalguide/guideline_index/Phenytoin_poisoning/
Phenytoin intoxication is usually benign and symptoms are dose-related ... Rapid IV administration: hypotension, bradycardia, arrhythmias.
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15 Dilantin Infatabs (phenytoin) dose, indications ... - PDR.Net
https://www.pdr.net/drug-summary/Dilantin-Infatabs-phenytoin-1814
[46974] [44772] Hypotension may occur, especially after high doses are given at high rates of administration. Although the risk of cardiovascular toxicity ...
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16 intravenous phenytoin - SA Health
https://www.sahealth.sa.gov.au/wps/wcm/connect/public+content/sa+health+internet/resources/policies/intravenous+phenytoin+-+sa+perinatal+practice+guidelines
IV phenytoin is used for emergency treatment for convulsive-status epilepticus. > Phenytoin should be used with caution in patients with hypotension, ...
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17 Phenytoin versus fosphenytoin for second-line treatment of ...
https://www.seizure-journal.com/article/S1059-1311(20)30146-1/fulltext
To avoid severe adverse events of arrythmia and hypotension, infusion rates of both drugs should not exceed the recommended intravenous IV ...
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18 Life-threatening cardiotoxicity due to chronic ... - Neurology India
https://www.neurologyindia.com/article.asp?issn=0028-3886;year=2009;volume=57;issue=2;spage=200;epage=202;aulast=su
Intravenous phenytoin can cause cardiac arrhythmias, hypotension, and cardiovascular collapse even when infused at the recommended rate.
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19 A Junctional Rhythm Caused by Administration of Intravenous ...
https://dergipark.org.tr/tr/download/article-file/664998
Phenytoin is an anticonvulsant drug used for treating many seizure ... Rapid administration of intravenous phenytoin can cause hypotension, bradyar-.
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20 Heart and blood pressure adverse effects of phenytoin
https://atlasofscience.org/heart-and-blood-pressure-adverse-effects-of-phenytoin/
In previous decades, several patients experienced adverse effects of intravenous phenytoin such as severe heart arrhythmias and decrease of ...
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21 Pediatric Emergency Medicine - Page 356 - Google Books Result
https://books.google.com/books?id=wpvux6RS-jsC&pg=PA356&lpg=PA356&dq=phenytoin+hypotension&source=bl&ots=x6TXGk4Hgf&sig=ACfU3U2pkshfdJTSXv3u7veBwj-A2e1GIQ&hl=en&sa=X&ved=2ahUKEwjoqNaTg9_7AhUghIkEHQkPAlQQ6AF6BQjJAhAD
... therapy for the termination of status epilepticus and when benzodiazepines fail.42 Side effects of phenytoin include hypotension, arrhythmias, asystole, ...
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22 cardiovascular risk associated with rapid infusion - Pfizer
https://labeling.pfizer.com/showlabeling.aspx?id=769
DILANTIN® (phenytoin sodium) injection, for intravenous or intramuscular use ... patients because of the risk of severe hypotension and cardiac arrhythmias.
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23 Hypotension: New Insights for the Healthcare Professional: ...
https://books.google.com/books?id=Zxqf0h91S88C&pg=PA33&lpg=PA33&dq=phenytoin+hypotension&source=bl&ots=UjMhh4yBaH&sig=ACfU3U3cgDeR6Ku4eYU3U9ga0Z8Jur1Qlg&hl=en&sa=X&ved=2ahUKEwjoqNaTg9_7AhUghIkEHQkPAlQQ6AF6BQjFAhAD
Use of lidocaine or phenytoin, both Vaughan Williams Class IB antiarrhythmic agents, has been reported as an effective adjunctive therapy in cases of severe ...
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24 Table of Medications that Increase Fall Risk
https://www.unmc.edu/patient-safety/_documents/meds-with-fall-risk-brand-generic-table-2013.pdf
Orthostatic hypotension, dizziness, syncope, ... hypotension, dizziness, syncope, bradycardia, ... phenytoin (Dilantin®) pregabalin (Lyrica®).
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25 Phenytoin poisoning | SpringerLink
https://link.springer.com/article/10.1385/NCC:3:2:161
Phenytoin toxicity may result from intentional overdose, ... complications such as arrhythmias and hypotension are rare in cases of phenytoin ingestion, ...
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26 Phenytoin Hospira 50 mg/ml Injection BP - print friendly - (emc)
https://www.medicines.org.uk/emc/product/3794/smpc/print
Hypotension may occur. Severe cardiotoxic reactions and fatalities have been reported with arrhythmias including bradycardia, atrial and ventricular depression, ...
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27 PHENYTOIN (Dilantin) | LHSC
https://www.lhsc.on.ca/critical-care-trauma-centre/phenytoin-dilantin
gingival hyperplasia. Drug Interactions: phenytoin + dopamine = increased hypotension; phenytoin + theophylline = decreased theophylline effect ...
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28 Phenytoin (Injectable) for Adult Patients Guideline
https://www.wacountry.health.wa.gov.au/~/media/WACHS/Documents/About-us/Policies/Specialised-Medication---Phenytoin--Injectable--for-Adult-Patients-Guideline.pdf?thn=0
Specialised Medication – Phenytoin (Injectable) ... Intravenous phenytoin has the potential to cause hypotension, cardiac.
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29 Phenytoin Side Effects: Common, Severe, Long Term
https://www.drugs.com/sfx/phenytoin-side-effects.html
Learn about the potential side effects of phenytoin. ... cardiomegaly, cerebral infarct, postural hypotension, pulmonary embolus, ...
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30 Phenytoin: Uses, Interactions, Mechanism of Action - DrugBank
https://go.drugbank.com/drugs/DB00252
Phenytoin is an anticonvulsant drug used in the prophylaxis and control of ... 50 mg per minute due to the risk of hypotension, bradycardia, and asystole.
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31 The ESC Handbook on Cardiovascular Pharmacotherapy
https://books.google.com/books?id=IrOYDwAAQBAJ&pg=PA864&lpg=PA864&dq=phenytoin+hypotension&source=bl&ots=gHnEFOLAI-&sig=ACfU3U3Ttp5o642gk2xjsc4sMcBA901_Hw&hl=en&sa=X&ved=2ahUKEwjoqNaTg9_7AhUghIkEHQkPAlQQ6AF6BQjMAhAD
Phenytoin: hypotension, bradycardia, intra-cardiac conduction blockade, arrhythmias including VF. • Topiramate: uncommon: bradycardia, palpitations, ...
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32 Management of Status Epilepticus | AAFP
https://www.aafp.org/pubs/afp/issues/2003/0801/p469.html
Adverse effects include respiratory suppression, hypotension, sedation, ... Phenytoin (Dilantin) is one of the most effective drugs for ...
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33 Phenytoin - WikiTox
http://www.wikitox.org/doku.php?id=wikitox:2.1.11.2.1_phenytoin
Phenytoin is an anticonvulsant that results in dose-dependent ataxia and CNS ... Cardiovascular toxicity (hypotension, bradycardia, ...
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34 Levetiracetam versus phenytoin for second-line treatment of ...
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)30724-X/fulltext
One participant who received phenytoin had serious adverse reactions related to study treatment (hypotension considered to be immediately ...
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35 Cardiovascular adverse effects of phenytoin - ResearchGate
https://www.researchgate.net/publication/286413424_Cardiovascular_adverse_effects_of_phenytoin
As the key words, "phenytoin, diphenylhydantoin, epilepsy, seizure, cardiac toxicity, asystole, arrhythmia, respiratory arrest, hypotension, ...
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36 Dopamine-phenytoin interaction. A cause of hypotension in ...
https://www.semanticscholar.org/paper/Dopamine-phenytoin-interaction.-A-cause-of-in-the-Bivins-Rapp/2c9df235442bbe63412f63035c09c8c5dbd38d81
Analysis of these cases led to a hypothesis that the interaction of dopamine and phenytoin produced the hypotension.
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37 Pharmacotherapy Update | Fosphenytoin (Cerebyx®)
https://www.clevelandclinicmeded.com/medicalpubs/pharmacy/novdec2004/fosphenytoin.htm
Cardiovascular side effects, including hypotension and dysrhythmias, can occur with both fosphenytoin and phenytoin.1 Unlike fosphenytoin, IV phenytoin has ...
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38 Phenytoin (Injection Route) Before Using - Mayo Clinic
https://www.mayoclinic.org/drugs-supplements/phenytoin-injection-route/before-using/drg-20072593
... may require an adjustment in the dose for patients receiving phenytoin injection. ... Heart rhythm problems or; Hypotension (low blood pressure) or ...
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39 Dyskinesia during concomitant usage of phenytoin and ...
https://pmj.bmj.com/content/97/1152/629
Side effects of phenytoin include hypotension, rash, nausea, nystagmus, dizziness, somnolence and ataxia. Rare side effects (<1%) include confusion, psychosis, ...
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40 Phenytoin - WikEM
https://wikem.org/wiki/Phenytoin
6.1 Toxicity symptoms by phenytoin level^; 6.2 Serious; 6.3 Common ... If infused too quickly, can lead to dysrhythmias, hypotension, ...
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41 Incidence and risk factors of hypotension after intravenous ...
https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcpt.12537
several benefits over intravenously administered phenytoin, ... aetiology and type, incidence of hypotension/cardiac arrhythmia and the ...
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42 DBL Phenytoin Injection BP 50 mg/mL Solution for ... - Medsafe
https://www.medsafe.govt.nz/profs/datasheet/d/dblphenytoininj.pdf
Reduction in rate of administration or discontinuation of dosing may be needed. Phenytoin should be used with caution in patients with hypotension and/or severe ...
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43 Intravenous Phenytoin for Status Epilepticus in Adults
http://www.leedsformulary.nhs.uk/docs/phenytoin%20administration%20guide.pdf
Loading dose: Patients who are NOT on phenytoin prior to admission. Loading Dose: ... If bradycardia or hypotension occurs, halve the infusion rate.
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44 Phenytoin toxicity - LITFL.com
https://litfl.com/phenytoin-toxicity/
Phenytoin intoxication can occur either with repeated supra therapeutic ... are only seen with rapid intravenous administration (hypotension, bradycardia, ...
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45 Phenytoin | Drugs - BNF - NICE
https://bnf.nice.org.uk/drugs/phenytoin/
View phenytoin information, including dose, uses, side-effects, pregnancy, ... Heart failure; hypotension; injection solutions alkaline (irritant to ...
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46 Pharmacology: NICU Handbook
https://uihc.org/childrens/educational-resources/pharmacology-nicu-handbook
Duration: 5-10 hours, Sedation, respiratory arrest, hypotension, ... 3Phenytoin, Loading: 15 - 20 mg/kg IV *Maintenance: 5 - 8 mg/kg/d
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47 CEREBYX®Adverse Reactions (fosphenytoin sodium) - US
https://www.pfizermedicalinformation.com/en-us/cerebyx/adverse-reactions
The more important adverse clinical reactions caused by the IV use of CEREBYX or phenytoin are cardiovascular collapse and/or CNS depression. Hypotension ...
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48 Note a Treatment algorithm for pediatric status epilepticus (SE ...
https://www.mainehealth.org/-/media/MaineHealth/PDFs/Clinical-Guidelines-and-Resources/Emergency-Medicine/Emergency-Medicine-Guidelines-and-Protocols/10318-Guideline-Evidence.pdf
Phenytoin group had 6/50 hypotension and 2/50 respiratory depression. No difference in SE control between under 18 vs over 18y/o. j. IV valproic acid bolus of ...
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49 Fosphenytoin Article - StatPearls
https://www.statpearls.com/ArticleLibrary/viewarticle/21936
Fosphenytoin is a water-soluble prodrug formulation of phenytoin. ... of serious cardiovascular events such as hypotension and arrhythmia.
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50 Guideline for Phenytoin Dose Calculations - GGC Medicines
https://handbook.ggcmedicines.org.uk/guidelines/central-nervous-system/guideline-for-phenytoin-dose-calculations/
Initial loading dose of phenytoin for status epilepticus ... rate monitoring is required during infusion as there is a risk of hypotension and bradycardia.
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51 What is the role of lidocaine or phenytoin in tricyclic ...
https://www.pharmgkb.org/literature/8228241
Deaths from TCA toxicity are typically due to cardiovascular events such as arrhythmias and hypotension. Cardiovascular toxicity may be multifactorial.
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52 IV Keppra in the Emergency Department for Prevention of ...
https://clinicaltrials.gov/ct2/show/NCT00510783
The purpose of this study is to compare these three drugs, phenytoin (Dilantin), ... life threatening cardiac arrhythmias, and severe hypotension.
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53 Medications with Fall Risk Precautions
https://www.hhs.texas.gov/sites/default/files/documents/doing-business-with-hhs/provider-portal/QMP/Medications.pdf
blood pressure), orthostatic hypotension (sudden drop in blood pressure when upright), syncope (fainting), ataxia (gait disturbance), blurred vision, ...
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54 Medications Containing Propylene Glycol and Risk of Anion ...
https://www.ebmconsult.com/articles/medications-containing-propylene-glycol-risk-anion-gap-metabolic-acidosis
Giving phenytoin too fast can cause hypotension and bradydysrhythmias because of the presence of propylene glycol. ICU Sedation:.
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55 Phenytoin as an Alternative Treatment for Preeclampsia
https://www.jognn.org/article/S0884-2175(15)33463-8/pdf
One patient experienced hypotension, but no cardiac ab- normalities were identified when electrocardiograms were administered. Phenytoin levels were assayed ...
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56 Phenytoin/Dilantin - Wheeless' Textbook of Orthopaedics
https://www.wheelessonline.com/orthopaedics-related-topics/phenytoin-dilantin/
Continuous monitoring of ECG and BP is necessary when administering IV Phenytoin loading dose (Beware: Hypotension); - Phenytoin serum levels are affected ...
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57 Guidelines for Use of Phenytoin (Dilantin )
https://www.unitypoint.org/blankchildrens/filesimages/for%20providers/nicu%20medications/phenytoin%20_dilantin_.pdf
Anticonvulsant, seizures refractory to phenobarbital alone. Possible Adverse Reactions. • Nystagmus, hypotension, bradycardia, arrhythmias, lethargy, vomiting, ...
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58 Diltiazem: a medicine used to treat high blood pressure - NHS
https://www.nhs.uk/medicines/diltiazem/
If you have high blood pressure, taking diltiazem helps to prevent future heart disease, ... medicines to treat epilepsy, such as carbamazepine or phenytoin ...
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59 Phenytoin vs Fosphenytoin
https://www.tandfonline.com/doi/pdf/10.1080/08998280.1999.11930167
cardiac monitoring is recommended during administration of in- travenous loading doses. In addition, intravenous phenytoin may cause hypotension if it is ...
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60 PHENYTOIN - Canterbury District Health Board
https://edu.cdhb.health.nz/Hospitals-Services/Health-Professionals/Neonatal-Clinical-Resources/Neonatal-Drug-Information-Sheets/Documents/Phenytoin-236792.pdf
Phenytoin Injection BP (DBL) ... 100 mg/ 2 mL (= 50 mg/mL) of phenytoin sodium in 2 mL ... Hypotension may occur when dopamine and phenytoin used.
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61 Phenytoin (PIM 416) - INCHEM
https://inchem.org/documents/pims/pharm/pim416.htm
Note on incompatibility: The mixing of phenytoin sodium with other drugs or its ... The risk of hypotension and arrythmia is minimal when intravenous ...
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62 Phenytoin Toxicology - TMedWeb
https://tmedweb.tulane.edu/pharmwiki/doku.php/phenytoin_toxicology
lethargy & confusion. hypotension. seizures. coma. Chronic side effects: gingival hyperplasia. hirsutism (excessive hairiness).
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63 Life-threatening cardiotoxicity due to chronic oral phenytoin ...
http://www.bioline.org.br/pdf?ni09057
Intravenous phenytoin can cause cardiac arrhythmias, hypotension, and cardiovascular collapse even when infused at the recommended rate.
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64 Phenytoin - NeoMED consensus group
https://www.anmfonline.org/wp-content/uploads/2021/06/phenytoin-22032021-5.0.pdf
Therapeutic Drug Concentration Monitoring: Note phenytoin elimination half-life is variable and ... If patient is hypotensive prior to starting phenytoin, ...
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65 Phenytoin (injection) - wikidoc
https://www.wikidoc.org/index.php/Phenytoin_(injection)
Phenytoin (injection) is an antiepileptic that is FDA approved for ... and patients with hypotension and severe myocardial insufficiency.
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66 Levetiracetam Compared With Phenytoin Or Fosphenytoin In ...
https://www.thennt.com/nnt/levetiracetam-compared-phenytoin-fosphenytoin-benzodiazepine-refractory-pediatric-status-epilepticus/
Major safety outcomes included hypotension, intubation, arrhythmia, and death. Seven relevant RCTs (n=1,575) were identified and their data ...
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67 Chapter 126. Phenytoin | Poisoning & Drug Overdose, 6e
https://accessmedicine.mhmedical.com/content.aspx?bookid=391§ionid=42069940
Death from isolated oral phenytoin overdose is extremely rare. Rapid intravenous injection, usually at rates exceeding 50 mg/min, can cause profound hypotension ...
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68 Phenytoin (Dilantin, Phenytek) - Davis Drug Guide
https://www.drugguide.com/ddo/view/Davis-Drug-Guide/109077/all/phenytoin
Adverse Reactions/Side Effects · Most listed are for chronic use of phenytoin · CV: CARDIAC ARREST, hypotension (↑ with iv phenytoin), bradycardia, tachycardia.
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69 Phenytoin - Uses, Side Effects, Substitutes, Composition And ...
https://www.lybrate.com/medicine/phenytoin
Phenytoin is used for Generalized Tonic-Clonic Seizure, Seizures etc. ... Phenytoin is used cautiously in hypotension (I.V. form contains ...
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70 Emergency management of the paediatric patient with ...
https://cps.ca/en/documents/position/emergency-management-of-the-paediatric-patient-with-convulsive-status-epilepticus
Side effects of both phenytoin and fosphenytoin include cardiac arrhythmias, bradycardia, and hypotension, such that continuous BP and ...
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71 Cerebellar Atrophy Following Long Term Phenytoin Overdose
https://www.e-bnr.org/DOIx.php?id=10.12786/bn.2011.4.1.69
Phenytoin is a commonly used antiepileptic drug, and its narrow ... Hypotension, cardiac arrhythmias, central nervous system depression are known side ...
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72 PHENYTOIN
https://www.bhs.org.au/bhsapps/govdoc/gdhtml/GDDRG0037-26601-53615.pdf
Phenytoin is an anti-convulsant medications used in the management of neonatal seizures. ... IV dosing can cause hypotension, arrhythmias, bradycardia, ...
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73 April 2013 Safe Use of an Old Drug
https://www.patientsafetysolutions.com/docs/April_2013_Safe_Use_of_an_Old_Drug.htm
Admittedly, the type of patient receiving IV phenytoin for arrhythmias was probably more vulnerable to the cardiac side effects but we commonly saw hypotension ...
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74 Phenytoin and Fosphenytoin | Basicmedical Key
https://basicmedicalkey.com/phenytoin-and-fosphenytoin/
Phenytoin is available in multiple dosage forms including an ... with phenytoin is depicted in Table 15-2.4,5 Hypotension is listed as a ...
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75 NHS Tayside Phenytoin Prescribing and Monitoring Guideline ...
https://www.nhstaysideadtc.scot.nhs.uk/approved/guidance/Phenytoin%20Prescribing%20and%20Monitoring%20Guidline.pdf
Phenytoin is an antiepileptic agent which is an effective, second line treatment for ... Hypotension, Prolonged QT interval and arrhythmias (rapid IV admin).
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76 Treating the symptom or treating the disease in neonatal ...
https://ijponline.biomedcentral.com/articles/10.1186/s13052-021-01027-2
Serious hypotensive episodes were reported in 39 (12%) patients treated. ... All 12 newborns treated with intravenous phenytoin and/or ...
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77 Phenytoin 2018
https://www.seslhd.health.nsw.gov.au/sites/default/files/groups/Royal_Hospital_for_Women/Neonatal/Neomed/neo17phenyabb.pdf
phenytoin may cause hypotension and may produce additive cardiac depressant effects. Adverse Reactions Administration-related reactions: Extravasation ...
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78 foianini - What is the role of lidocaine or phenytoin in tricyclic ...
http://degreesofclarity.com/emsbasics/library/foianini%20-%20What%20is%20the%20role%20of%20lidocaine%20or%20phenytoin%20in%20tricyclic%20%20%20antidepressant-induced%20cardiotoxicity.pdf
Clinical Toxicology vol. 48 no. 4 2010. Lidocaine and phenytoin in TCA cardiotoxicity. 327 and hypotension. Sodium bicarbonate has also been shown to.
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79 Orthostatic Hypotension Shared Care Agreement
https://westessexccg.nhs.uk/your-health/medicines-optimisation-and-pharmacy/shared-care-medicines/259-orthostatic-hypotension-shared-care-agreement/file
Orthostatic (or postural) hypotension is defined as a sustained reduction of systolic blood pressure of at ... carbamazepine, phenytoin,.
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80 Dopamine PDF - Teton County, WY
https://www.tetoncountywy.gov/DocumentCenter/View/2565/17-110-Dopamine-PDF
Dopamine is commonly used in the treatment of hypotension associated with cardiogenic and ... When administered with phenytoin, hypotension, bradycardia,.
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81 Status Epilepticus - EMCrit Project
https://emcrit.org/ibcc/sz/
Hypotension. Phenobarbital is metabolized by CYP2C9 and 2C19, which may lead to drug-drug interactions. Phenytoin may reduce phenobarbital ...
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82 Dilantin Toxicity - Family Practice Notebook
https://fpnotebook.com/mobile/neuro/pharm/DlntnTxcty.htm
This page includes the following topics and synonyms: Dilantin Toxicity, ... Manage Hypotension · Gastric Decontamination; Treat complete Heart Block.
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83 The 7 Common Paxlovid Drug Interactions - GoodRx
https://www.goodrx.com/paxlovid/drug-interactions
Common examples are medications that treat high cholesterol, high blood pressure, and migraines. ... Phenytoin (Dilantin, Phenytek).
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84 PhenyTOIN - BCEHS Handbook
https://handbook.bcehs.ca/drug-monographs/phenytoin/
Cardiovascular: Cardiac arrhythmia, cardiac conduction disturbance (depression), circulatory shock, hypotension, ventricular fibrillation; Central nervous ...
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85 PHENYTOIN injectable - MSF Medical Guidelines
https://medicalguidelines.msf.org/en/viewport/EssDr/english/phenytoin-injectable-32409524.html
Contra-indications, adverse effects, precautions · hypotension, bradycardia, conduction disorders, depression of the central nervous system when administered too ...
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86 Generalized Convulsive Status Epilepticus in Adults: Initial ...
https://www.uspharmacist.com/article/generalized-convulsive-status-epilepticus-in-adults-initial-pharmacologic-management
Because of the increased incidence of hypotension in the elderly population, it is recommended that phenytoin be infused no faster than 25 mg ...
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87 Fosphenytoin - Surgicalcriticalcare.net
http://www.surgicalcriticalcare.net/Guidelines/fosphenytoin.pdf
likely to occur when large doses of undiluted phenytoin are given through a small-bore catheter in a peripheral vein. Hypotension and arrhythmias are ...
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88 FULL TEXT -Cardiac arrest after intravenous infusion of ...
https://www.ijcasereportsandimages.com/archive/2018-articles/2018100013Z01100879KI-inoue/100013Z01100879KI-full-text.php
Phenytoin, used to treat status epilepticus, is associated with cardiovascular toxicity including arrhythmia and hypotension. Recently, the phenytoin ...
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89 Phenytoin – Loading Dose Guide (Adults) - Dorset Formulary
http://www.dorsetformulary.nhs.uk/docs/bnf04/RBCH%20PHT%20Phenytoin%20Loading%20dose%20guidelines.pdf
If a patient is already taking regular phenytoin (Epanutin) reliably they may not ... administration may result in hypotension, CNS depression, arrhythmias, ...
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90 Dilantin (Phenytoin) for Pain Management in Multiple Sclerosis
https://multiplesclerosisnewstoday.com/dilantin-phenytoin-for-pain-management-in-msdilantin-phenytoin-for-pain-management-in-ms/
... life-threatening risks) regarding cardiovascular risk if phenytoin is given by injection, with an existing a risk of arrhythmias, or severe hypotension.
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91 Diltiazem (Cardizem, Cartia XT) | Davis's Drug Guide
https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Drug-Guide/51221/all/dilTIAZem
hypotension may occur when used with fentanyl, other antihypertensives, ... ivabradine, or phenytoin may result in bradycardia, conduction defects, or HF; ...
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92 Phenytoin IV protocol.pdf - Cree Health
https://www.creehealth.org/sites/default/files/Phenytoin%20IV%20protocol.pdf
Procedure for the IV administration of Phenytoin. Sodium (Dilantin) at a high ... Fast administration can provoke severe hypotension and depression of CNS.
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93 Paxlovid for the treatment of COVID-19 - EMEA/H/A-5(3)/1513
https://www.ema.europa.eu/en/documents/referral/paxlovid-pf-07321332-ritonavir-covid-19-article-53-procedure-conditions-use-conditions-distribution_en.pdf
hypotension (see section 5.4). Analgesics. Pethidine, piroxicam, propoxyphene ... alfuzosin may lead to severe hypotension ... Phenytoin may decrease serum.
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94 Phenytoin-induced Stevens-Johnson syndrome with myocarditis
https://www.dovepress.com/phenytoin-induced-stevens-johnson-syndrome-with-myocarditis-a-rare-cas-peer-reviewed-fulltext-article-IMCRJ
Diffuse myocardial involvement causes hypotension and thromboembolic events. Cardiac Magnetic Resonance Imaging and cardiac biomarker ...
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95 PHENYTOIN SODIUM INJECTION, USP - FDA.report
https://fda.report/DailyMed/ab923d09-747d-4527-9bdf-2c807a5775d2
... of the risk of severe hypotension and cardiac arrhythmias. Careful cardiac monitoring is needed during and after administering intravenous Phenytoin.
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96 Case Study Answers and Discussion: Clinically Important ...
https://www.phrmafoundation.org/case-study-answers-and-discussion-clinically-important-drug-interactions/
Therefore, phenytoin may increase in EFV metabolism and causes a decrease in ... Discuss the complex drug interactions that contributed to hypotension in ...
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